3,040 results match your criteria Hookworms


Intestinal parasites and lungworms in stray, shelter and privately owned cats of Switzerland.

Parasitol Int 2018 Dec 12. Epub 2018 Dec 12.

University of Zurich, Vetsuisse Faculty, Institute of Parasitology, Winterthurerstrasse 266a, 8057 Zurich, Switzerland. Electronic address:

Endoparasitic infections represent relevant causes of respiratory and gastrointestinal diseases in cats. The aim of the study was to investigate the occurrence of endoparasites in Swiss cats in order to evaluate the risk of onset of parasitic diseases and potential correlated zoonoses. Therefore 664 faecal samples from privately owned (n = 299), shelter (n = 197) and stray (n = 168) cats were investigated by sedimentation-flotation and 468 samples additionally by the Baermann technique. Read More

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December 2018
1 Read

Mitochondrial DNA reveals species composition and phylogenetic relationships of hookworms in northeastern Brazil.

Infect Genet Evol 2018 Nov 30. Epub 2018 Nov 30.

Laboratory of Epidemiology and Molecular Systematics, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil; Oswaldo Cruz Foundation, Teresina, Piauí, Brazil. Electronic address:

Hookworm infection persists focally in rural communities in Brazil. In this study, we analyze the mitochondrial nucleotide sequences obtained from hookworms infecting humans in order to characterize species composition and assess their genetic diversity and phylogenetic relationships. Field expeditions and cross-sectional surveys were carried out in three Brazilian municipalities from 2013 to 2017: Nossa Senhora de Nazaré (n = 605) and Teresina (n = 297), in the state of Piauí, and Russas (n = 213) in the State of Ceará. Read More

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November 2018
3 Reads

A randomized, blinded, controlled, multi-centered field study assessing the treatment of gastrointestinal nematode infections in cats with fluralaner plus moxidectin spot-on solution (Bravecto® Plus).

Parasit Vectors 2018 Nov 19;11(1):589. Epub 2018 Nov 19.

MSD Animal Health Innovation GmbH, Zur Propstei, 55270, Schwabenheim, Germany.

Background: A spot-on formulation containing fluralaner (280 mg/ml) plus moxidectin (14 mg/ml) (Bravecto® Plus) was developed for the treatment of nematode infections as well as providing 12 weeks of protection against insect and acarine parasites in cats. The effectiveness and safety of this product against feline gastrointestinal nematodes was assessed in naturally-infested, client-owned cats under field conditions in Albania, Bulgaria, Germany and Hungary.

Methods: To be eligible for enrollment in this investigator-blinded study cats had to be at least 10 weeks-old, weigh at least 1. Read More

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November 2018
1 Read

Morphometrical and molecular evidence suggests cryptic diversity among hookworms (Nematoda: Uncinaria) that parasitize pinnipeds from the south-eastern Pacific coasts.

J Helminthol 2018 Nov 15:1-9. Epub 2018 Nov 15.

Departamento de Ciencias Biológicas,Facultad de Ciencias,Universidad Santo Tomás,Los Carrera 753,Osorno,Chile.

Hookworms of the genus Uncinaria parasitize pinniped pups in various locations worldwide. Four species have been described, two of which parasitize pinniped pups in the southern hemisphere: Uncinaria hamiltoni parasitizes Otaria flavescens and Arctocephalus australis from the South American coast, and Uncinaria sanguinis parasitizes Neophoca cinerea from the Australian coast. However, their geographical ranges and host specificity are unknown. Read More

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November 2018

Kato-Katz thick smears as a DNA source of soil-transmitted helminths.

J Helminthol 2018 Nov 15:1-4. Epub 2018 Nov 15.

Laboratório de Epidemiologia e Sistemática Molecular,Instituto Oswaldo Cruz,Fundação Oswaldo Cruz,Pavilhão Leônidas Deane,sala 308,Avenida Brasil, 4365, Manguinhos, Rio de Janeiro,Brazil.

Despite the reduction in the prevalence of soil-transmitted helminthiases in many regions of the world, morbidity rates remain high in some rural regions. The Kato-Katz technique is a simple, inexpensive and field-applicable tool commonly used for the diagnosis and worm-burden characterization of these infections. Molecular studies have revolutionized our understanding of the epidemiology and evolutionary genetics of parasites. Read More

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November 2018
9 Reads

Baseline Mapping of Schistosomiasis and Soil Transmitted Helminthiasis in the Northern and Eastern Health Regions of Gabon, Central Africa: Recommendations for Preventive Chemotherapy.

Trop Med Infect Dis 2018 Nov 11;3(4). Epub 2018 Nov 11.

Control Program of Parasitic Diseases, Libreville BP 2434, Gabon.

In order to follow the Preventive Chemotherapy (PC) for the transmission control as recommended by WHO, Gabon initiated in 2014 the mapping of Schistosomiasis and Soil Transmitted Helminthiasis (STH). Here, we report the results of the Northern and Eastern health regions, representing a third of the land area and 12% of its total population. All nine departments of the two regions were surveyed and from each, five schools were examined with 50 schoolchildren per school. Read More

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November 2018
2 Reads

Prevalence of Gastrointestinal Parasitic Infections and Assessment of Deworming Program among Cattle and Buffaloes in Gampaha District, Sri Lanka.

Biomed Res Int 2018 9;2018:3048373. Epub 2018 Oct 9.

Department of Biosystems Engineering, Faculty of Agriculture and Plantation Management, Wayamba University, Makandura, Sri Lanka.

Gastrointestinal (GI) parasitic infection is a serious issue in cattle management. The effects of GI parasites may vary with age, sex of cattle, nutritional condition, and severity of infection. Prevalence of GI parasites among cattle population in Gampaha District has not been studied and there is no published study available. Read More

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October 2018
7 Reads

Immune-mediated hookworm clearance and survival of a marine mammal decrease with warmer ocean temperatures.

Elife 2018 11 6;7. Epub 2018 Nov 6.

Department of Pathology, College of Veterinary Medicine, University of Georgia, Athens, United States.

Increases in ocean temperature are associated with changes in the distribution of fish stocks, and the foraging regimes and maternal attendance patterns of marine mammals. However, it is not well understood how these changes affect offspring health and survival. The maternal attendance patterns and immunity of South American fur seals were assessed in a rookery where hookworm disease is the main cause of pup mortality. Read More

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November 2018
7 Reads

Terror in the dirt: Sensory determinants of host seeking in soil-transmitted mammalian-parasitic nematodes.

Int J Parasitol Drugs Drug Resist 2018 Dec 26;8(3):496-510. Epub 2018 Oct 26.

Department of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, CA, 90095, USA. Electronic address:

Infection with gastrointestinal parasitic nematodes is a major cause of chronic morbidity and economic burden around the world, particularly in low-resource settings. Some parasitic nematode species, including the human-parasitic threadworm Strongyloides stercoralis and human-parasitic hookworms in the genera Ancylostoma and Necator, feature a soil-dwelling infective larval stage that seeks out hosts for infection using a variety of host-emitted sensory cues. Here, we review our current understanding of the behavioral responses of soil-dwelling infective larvae to host-emitted sensory cues, and the molecular and cellular mechanisms that mediate these responses. Read More

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December 2018
4 Reads

Helminth and respiratory mite lesions in Pinnipeds from Punta San Juan, Peru.

Acta Parasitol 2018 Dec;63(4):839-844

Instituto de Patología Animal, Facultad de Ciencias Veterinarias, Universidad Austral de Chile, Isla Teja s/n, 5090000, Valdivia, Chile.

The tissues and parasites collected from Peruvian fur seals (Arctocephalus australis) and South American sea lions (Otaria byronia) found dead at Punta San Juan, Peru were examined. The respiratory mite, Orthohalarachne attenuata infected 3 out of 32 examined fur seals and 3 out of 8 examined sea lions, however caused moderate to severe lymphohistiocytic pharyngitis only in fur seals. Hookworms, Uncinaria sp, infected 6 of the 32 examined fur seals causing variable degrees of hemorrhagic and eosinophilic enteritis. Read More

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December 2018
1 Read

[Current status of human hookworm infection in Jiangxi Province in 2014].

Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi 2018 Jun;30(4):446-448

Jiangxi Provincial Institute of Parasitic Diseases, Nanchang 330096, China.

Objective: To understand the status of human hookworm ( or ) infection in Jiangxi Province.

Methods: A stratified cluster random sampling was conducted based on the geographical location and economic condition in 2014. Kato-Katz's thick smear method was used for stool examinations, and filter paper cultivation was conducted for distinguishing the species of hookworms. Read More

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June 2018
2 Reads

Standardization and application of a modified RFLP-PCR methodology for analysis of polymorphisms linked to treatment resistance in Ancylostoma braziliense.

Parasit Vectors 2018 Oct 9;11(1):540. Epub 2018 Oct 9.

Departamento de Parasitologia, L4 237, Laboratório de Parasitologia Molecular, Universidade Federal de Minas Gerais, Instituto de Ciências Biológicas, Avenida Presidente Antônio Carlos, 6627, Pampulha, Belo Horizonte, Minas Gerais, CEP 31270-901, Brazil.

Background: Single nucleotide polymorphisms (SNPs) in codons 167, 198 and 200 of the beta-tubulin isotype 1 gene are associated with benzimidazoles resistance in many helminths. Codon 167 mutation has never been described in hookworms; however, polymorphisms in codons 198 and 200 have been described for Ancylostoma caninum and Necator americanus. These mutations have never been investigated in Ancylostoma braziliense; therefore, it is not known if they are present in this species and whether they are correlated with treatment resistance. Read More

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October 2018
2 Reads

A community-based surveillance of gastrointestinal helminthiasis among pregnant women in Ibadan, South West Nigeria.

Niger J Clin Pract 2018 Oct;21(10):1368-1373

Department of Paediatrics, Obstetrics and Gynaecology and Medical Microbiology, College of Medicine, University of Ibadan and University College Hospital, Ibadan, Nigeria.

Background: : Intestinal helminthiasis is a major public health problem in Africa. Helminthic infection in pregnant women causes loss of appetite, poor nutrient absorption, gastrointestinal impairment, iron deficiency, and iron deficiency anemia resulting in low birth weights and preterm births. The main aim of this study is to assess the prevalence of helminthic infections in pregnant women in rural and peri-urban communities of Ibadan. Read More

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October 2018
2 Reads

infection in human and nonhuman primates in selected areas of Oromia Regional State, Ethiopia.

J Vector Borne Dis 2018 Apr-Jun;55(2):116-121

Aklilu Lemma Institute of Pathobiology, Addis Ababa University, Ethiopia.

Background & Objectives: The transmission of schistosomiasis, caused by trematodes of the genus Schistosoma, relies on freshwater snails that act as an intermediate host while human and other mammalian act as the definitive hosts. Many non-human primates (NHPs) such as Chlorocebus aethiops (vervet) and Papio anubis (baboon) are reported to be infected with Schistosoma mansoni in Ethiopia, but the role they play in parasite maintenance and transmission is still not clear. The objective of this study was, therefore, to determine the prevalence of S. Read More

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December 2018
7 Reads

The Unique Life Cycle of Strongyloides stercoralis and Implications for Public Health Action.

Trop Med Infect Dis 2018 May 25;3(2). Epub 2018 May 25.

School of Health, Medical and Applied Sciences, Central Queensland University, Rockhampton, QLD 4700, Australia.

has one of the most complex life cycles of the human-infecting nematodes. A common misconception in medical and public health professions is that in its biology is akin to other intestinal nematodes, such as the hookworms. Despite original evidence provided by medical and veterinary research about this unique helminth, many assumptions have entered the scientific literature. Read More

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May 2018
3 Reads

A Survey of Intestinal Parasites of Domestic Dogs in Central Queensland.

Trop Med Infect Dis 2017 Nov 21;2(4). Epub 2017 Nov 21.

School of Health, Medical and Applied Sciences, Central Queensland University, North Rockhampton, QSD 4702, Australia.

Australia has a very high rate of dog ownership, which in some circumstances may lead to exposure to zoonotic parasitic diseases from those companion animals. Domestic dog faecal samples ( = 300) were collected from public spaces and private property in the greater Rockhampton (Central Queensland) region and tested for intestinal helminths and protozoa by direct microscopy, two flotation methods and a modified acid-fast stain for cryptosporidia. Intestinal parasites detected included hookworms (25%), complex (9%), (3%), (3%), (1%) and (1%), spp. Read More

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November 2017
3 Reads

Contamination of selected recreational areas in Lublin Province, Eastern Poland, by eggs of Toxocara spp., Ancylostoma spp. and Trichuris spp.

Ann Agric Environ Med 2018 Sep 8;25(3):460-463. Epub 2018 Aug 8.

Department of Biological Threats of Health and Parasitology, Institute of Rural Health, Lublin, Poland.

Introduction: While using recreational areas, people take with them accompanying animals (dogs, cats). These animals are the main source and reservoir of dangerous zoonoses, including parasitoses caused by genera of nematodes, also called roundworms, Toxocara spp., Trichuris spp. Read More

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September 2018
4 Reads

Development and Evaluation of a Multiplex Quantitative Real-Time Polymerase Chain Reaction for Hookworm Species in Human Stool.

Am J Trop Med Hyg 2018 Nov;99(5):1186-1193

Faculty of Veterinary and Agricultural Sciences, University of Melbourne, Parkville, Australia.

Hookworm disease caused by , , and affects half a billion people worldwide. The prevalence and intensity of infection of individual hookworm species are vital for assessing morbidity and generating targeted intervention programs for their control. The present study aims to evaluate a multiplex real-time quantitative PCR (qPCR) assay to determine the prevalence and egg intensity of all three hookworm species and compare this with standard microscopy and published genus-based conventional and real-time multiplex qPCRs. Read More

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November 2018
2 Reads

PCR-RFLP screening of polymorphisms associated with benzimidazole resistance in Necator americanus and Ascaris lumbricoides from different geographical regions in Brazil.

PLoS Negl Trop Dis 2018 09 17;12(9):e0006766. Epub 2018 Sep 17.

Departament of Parasitology, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.

Ascaris lumbricoides and Necator americanus are soil-transmitted parasites with global geographic distribution, and they represent some of the most common and neglected infections in the world. Periodic treatment with mass drug administration (MDA) in endemic areas is the recommended action put forth by the World Health Organization. However, MDA can cause the selection of subpopulations that possess the genetic ability to overcome the mechanism of drug action. Read More

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September 2018
1 Read

Prevalence of intestinal parasitic infections and associated risk factors for hookworm infections among primary schoolchildren in rural areas of Nakhon Si Thammarat, southern Thailand.

BMC Public Health 2018 Sep 14;18(1):1118. Epub 2018 Sep 14.

Nopphitam Hospital, Nakhon Si Thammarat, Thailand.

Background: Soil-transmitted helminth (STH) infections are among the most common type of infections worldwide and are widely distributed in tropical areas. In rural areas of southern Thailand where most land is used for agriculture, children are at risk of acquiring parasites, especially STHs. Assessing the current situation regarding parasitic infection in these areas is a prerequisite for developing appropriate control measures. Read More

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September 2018
7 Reads

Comparison of individual and pooled diagnostic examination strategies during the national mapping of soil-transmitted helminths and Schistosoma mansoni in Ethiopia.

PLoS Negl Trop Dis 2018 09 10;12(9):e0006723. Epub 2018 Sep 10.

Department of Virology, Parasitology and Immunology, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium.

Background: Laboratory-based studies have highlighted that pooling stool and urine samples can reduce costs and diagnostic burden without a negative impact on the ability to estimate the intensity of soil-transmitted helminth (STH, Ascaris lumbricoides, Trichuris trichiura and hookworms) and schistosome infections (Schistosoma mansoni and S. haematobium). In this study, we compare individual and pooled stool examination strategies in a programmatic setting. Read More

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September 2018
1 Read

Prevalence of intestinal parasites, with emphasis on the molecular epidemiology of Giardia duodenalis and Blastocystis sp., in the Paranaguá Bay, Brazil: a community survey.

Parasit Vectors 2018 Aug 30;11(1):490. Epub 2018 Aug 30.

Parasitology Reference and Research Laboratory, National Centre for Microbiology, Ctra. Majadahonda-Pozuelo Km 2, 28220 Majadahonda, Madrid, Spain.

Background: Intestinal protozoan parasites are major contributors to the global burden of gastrointestinal disease causing significant socioeconomic consequences. Children living in resource-poor settings with restricted access to water and sanitary services are particularly at risk of these infections.

Methods: A prospective, community-based, cross-sectional survey was conducted in Paraná (southern Brazil) between May 2015 and May 2016. Read More

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August 2018
10 Reads

Burden of intestinal helminths and associated factors three years after initiation of mass drug administration in Arbaminch Zuria district, Southern Ethiopia.

BMC Infect Dis 2018 Aug 29;18(1):435. Epub 2018 Aug 29.

Department of Public Health, College of Medicine and Health Sciences, Arba Minch University, Arba Minch, Ethiopia.

Background: Epidemiological information on the burden of various parasitic infections and associated factors in different localities is indispensable to develop appropriate control and prevention measures as well as to monitor and evaluate existing programs. Hence the aim of the present study was to assess the prevalence and associated factors of intestinal helminths among school age children in Arbaminch Zuria district, Southern Ethiopia.

Methods: A community based cross-sectional study was conducted by recruiting 391 primary school age children. Read More

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August 2018
6 Reads
2.610 Impact Factor

Prevalence of Atopy following Mass Drug Administration with Albendazole: A Study in School Children on Flores Island, Indonesia.

Int Arch Allergy Immunol 2018;177(3):192-198. Epub 2018 Aug 21.

Department of Parasitology, Leiden University Medical Center, Leiden, the Netherlands.

Background: In many rural areas of tropical countries such as Indonesia, the prevalence of soil-transmitted helminths (STH) infections remains high. At the same time, the burden of allergic disorders in such rural areas is reported to be low and inversely associated with helminth infections. To reduce the morbidity and transmission of helminth infections, the world health organization recommends preventive treatment of school children by providing mass drug administration (MDA) with albendazole. Read More

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December 2018
3 Reads

Intestinal parasitism and nutritional status among indigenous children from the Argentinian Atlantic Forest: Determinants of enteroparasites infections in minority populations.

Acta Trop 2018 Nov 17;187:248-256. Epub 2018 Aug 17.

Department of Environmental and Global Health, University of Florida, Gainesville, FL 32610, USA; Emerging Pathogens Institute, University of Florida, Gainesville, FL 32610, USA.

Objective: Intestinal parasitoses, especially in the less favored populations of tropical and subtropical areas, are a scourge of high impact in public health. We conducted a cross-sectional survey to investigate the prevalence of helminths and protozoa pathogens, malnutrition, and their determinants in children from indigenous Mbyá Guaraní villages of Iguazú, in the subtropical Atlantic Forest of Argentina.

Methods: Parasitological assessment was performed using a combination of flotation, sedimentation, and centrifugation techniques, as well as temporal and permanent stains. Read More

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November 2018
8 Reads

Domiciliary Cockroaches as Carriers of Human Intestinal Parasites in Lagos Metropolis, Southwest Nigeria: Implications for Public Health.

J Arthropod Borne Dis 2018 Jun 13;12(2):141-151. Epub 2018 Jun 13.

Department of Zoology, University of Lagos, Akoka, Lagos, Nigeria.

Background: Domiciliary cockroaches are obnoxious pests of significant medical importance. We investigated the prevalence of human intestinal parasites in cockroaches and its attendant public health importance.

Methods: Overall, 749 cockroaches (, 509, , 240) caught by trapping from 120 households comprising 3 different housing types in Somolu, Lagos metropolis, southwest Nigeria, in 2015 were screened for human intestinal parasites using standard parasitological techniques. Read More

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June 2018
1 Read

MaxEnt modeling of soil-transmitted helminth infection distributions in Thailand.

Parasitol Res 2018 Nov 17;117(11):3507-3517. Epub 2018 Aug 17.

Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, 40002, Thailand.

Infections due to soil-transmitted helminths (STHs), i.e. Ascaris lumbricoides, Trichuris trichiura, hookworms, and Strongyloides stercoralis, are widely distributed in tropical and subtropical areas in which approximately 1. Read More

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November 2018
4 Reads

Host- and Helminth-Derived Endocannabinoids That Have Effects on Host Immunity Are Generated during Infection.

Infect Immun 2018 Nov 25;86(11). Epub 2018 Oct 25.

Division of Biomedical Sciences, University of California, Riverside, Riverside, California, USA

Helminths have coevolved with their hosts, resulting in the development of specialized host immune mechanisms and parasite-specific regulatory products. Identification of new pathways that regulate helminth infection could provide a better understanding of host-helminth interaction and may identify new therapeutic targets for helminth infection. Here we identify the endocannabinoid system as a new mechanism that influences host immunity to helminths. Read More

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November 2018

Soil-transmitted helminth infections, anemia and undernutrition among schoolchildren in Yirgacheffee, South Ethiopia.

BMC Res Notes 2018 Aug 13;11(1):585. Epub 2018 Aug 13.

Department of Microbial, Cellular and Molecular Biology, College of Natural Sciences, Addis Ababa University, PO Box 1176, Addis Ababa, Ethiopia.

Objective: Current data on soil-transmitted helminth infections, anemia and malnutrition that are largely neglected is vital to the control and management of them in a specific setting. This study was, therefore, aimed at determining the status of the three health concerns in one of the high-risk groups, schoolchildren, in South Ethiopia.

Results: Among the 443 sampled schoolchildren, 54% were infected with soil-transmitted helminths (STHs) and 15. Read More

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August 2018
1 Read

Dynamic changes in human-gut microbiome in relation to a placebo-controlled anthelminthic trial in Indonesia.

PLoS Negl Trop Dis 2018 08 9;12(8):e0006620. Epub 2018 Aug 9.

Department of Parasitology, Leiden University Medical Centre, Leiden, The Netherlands.

Background: Microbiome studies suggest the presence of an interaction between the human gut microbiome and soil-transmitted helminth. Upon deworming, a complex interaction between the anthelminthic drug, helminths and microbiome composition might occur. To dissect this, we analyse the changes that take place in the gut bacteria profiles in samples from a double blind placebo controlled trial conducted in an area endemic for soil transmitted helminths in Indonesia. Read More

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August 2018
5 Reads

The life history strategy of a fur seal hookworm in relation to pathogenicity and host health status.

Int J Parasitol Parasites Wildl 2018 Dec 7;7(3):251-260. Epub 2018 Jul 7.

Department of Pathology, College of Veterinary Medicine, University of Georgia, 501 DW Brooks Dr, Athens, GA, 30602, USA.

The strategies that parasites use to exploit their hosts can lead to adverse effects on human and animal populations. Here, we describe the life cycle, epidemiology, and consequences of hookworm () disease in South American fur seals (), and propose that hookworm adaptation to fur seal life history traits has led to maximizing transmission at high levels of parasite-induced anemia and mortality. Fur seal pups acquire hookworms during their first days of life through their mothers' colostrum and most adult hookworms are expelled from the pups' intestine 30-65 days later. Read More

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December 2018
7 Reads

Prevalence of intestinal helminths of red foxes (Vulpes vulpes) in central Europe (Poland): a significant zoonotic threat.

Parasit Vectors 2018 Jul 28;11(1):436. Epub 2018 Jul 28.

National Veterinary Research Institute, al. Partyzantow 57, 24-100, Pulawy, Poland.

Background: The red fox (Vulpes vulpes) is widely distributed in the world; in central Europe, it is the most numerous wild species of the family Canidae. It can play the role of a definitive host for many intestinal parasites, including zoonotic helminths. Poland, with its geographical location (central Europe), is an interesting area for parasitological investigations of this species. Read More

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July 2018
3 Reads

Thermosensation: Human Parasitic Nematodes Use Heat to Hunt Hosts.

Curr Biol 2018 Jul;28(14):R795-R798

Department of Biology and National Center for Behavioral Genomics, Brandeis University, Waltham, MA 02454, USA. Electronic address:

Temperature is a critical host-emitted cue for many parasitic species. A recent study shows that skin-penetrating human parasitic hookworms and threadworms exhibit adaptive host-seeking behaviors that are based on their temperature experience, opening up possibilities for new intervention strategies. Read More

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July 2018
1 Read

Gastrointestinal helminths in farmers and their ruminant livestock from the Coastal Savannah zone of Ghana.

Parasitol Res 2018 Oct 21;117(10):3183-3194. Epub 2018 Jul 21.

School of Veterinary and Life Sciences, Murdoch University, 90 South Street, Murdoch, Western Australia, Australia.

To identify the gastrointestinal helminths of veterinary, zoonotic and public health importance in farmers and their ruminant livestock in Ghana, faecal samples were collected from 95 farmers and their livestock (cattle = 328, sheep = 285 and goats = 217) and examined by microscopy and/or molecular techniques. Overall, 21 farmers tested positive for at least one gastrointestinal helminth, 80.9% of which were single infections and 19. Read More

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October 2018
4 Reads
2.330 Impact Factor

Epidemiology and morbidity of hookworm-related cutaneous larva migrans (HrCLM): Results of a cohort study over a period of six months in a resource-poor community in Manaus, Brazil.

PLoS Negl Trop Dis 2018 07 19;12(7):e0006662. Epub 2018 Jul 19.

Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Microbiology and Infection Immunology, Berlin, Germany.

Background: Hookworm-related cutaneous larva migrans (HrCLM) is a neglected parasitic skin disease, widespread in resource-poor communities in tropical and subtropical countries. Incidence and risk factors have never been investigated in a cohort study.

Methodology/principal Findings: To understand the seasonal epidemiology of HrCLM, an open cohort of 476 children in a resource-poor community in Manaus, Brazil was examined for HrCLM monthly over a period of 6 months. Read More

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July 2018
2 Reads

[Differentiating the morphology of infective larvae between two human hookworms].

Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi 2018 Jun;30(3):359-360

Jiangsu Institute of Parasitic Diseases, Wuxi 214064, China.

The morphological differentiation of the infective larvae between human and is of great significance for the epidemiological survey of hookworm diseases and human parasitology teaching. Understanding of features of the oral spear and transverse lines on the tunica vaginalis is able to accurately differentiate the infective larvae between these two human hookworms. Read More

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Diaphanocephalus galeatus (Nematoda: Diaphanocephalidae), a poorly known parasite of lizards: redescription, first genetic characterization and a revision of its congeners from Brazil.

J Helminthol 2018 Jul 16:1-7. Epub 2018 Jul 16.

Programa de Pós-Graduação em Biologia Animal,Instituto de Biociências, Universidade Federal de Mato Grosso do Sul,Av. Costa e Silva s/n°,CEP 79070-900,Campo Grande, MS,Brazil.

Diaphanocephalus galeatus collected from the small intestine of the lizard Dracaena paraguayensis in the Pantanal wetlands, State of Mato Grosso do Sul, Brazil, is redescribed. Genetic characterization and observations using scanning electron microscopy (SEM) were performed for the first time. The vouchers of D. Read More

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Hookworms Make Us Human: The Microbiome, Eco-immunology, and a Probiotic Turn in Western Health Care.

Authors:
Jamie Lorimer

Med Anthropol Q 2018 Jul 13. Epub 2018 Jul 13.

School of Geography and the Environment, University of Oxford.

Historians of science have identified an ecological turn underway in immunology, driven by the mapping of the human microbiome and wider environmentalist anxieties. A figure is emerging of the human as a holobiont, composed of microbes and threatened by both microbial excess and microbial absence. Antimicrobial approaches to germ warfare are being supplemented by probiotic approaches to restoring microbial life. Read More

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Prevalence and distribution of soil-transmitted helminth infections in Nigerian children: a systematic review and meta-analysis.

Infect Dis Poverty 2018 Jul 9;7(1):69. Epub 2018 Jul 9.

Department of Veterinary Public Health and Preventive Medicine, University of Jos, PMB 2084, Jos, Nigeria.

Background: Soil transmitted helminth (STH) infections still remain a notable health problem in resource-limited countries due to difficulties in the implementation of control measures. In Nigeria for instance, despite several community-based and provincial reports, national data on prevalence, burdens and risk zones (RZs) for STH infections are lacking.

Methods: The present study employed the recommendations of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) to determine the prevalence, distribution and RZs for STH infections among Nigerian children through a meta-analysis of data published between 1980 and 2015. Read More

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July 2018
13 Reads

Focal persistence of soil-transmitted helminthiases in impoverished areas in the State of Piaui, Northeastern Brazil.

Rev Inst Med Trop Sao Paulo 2018 28;60:e24. Epub 2018 Jun 28.

Laboratório de Epidemiologia e Sistemática Molecular, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, Rio de Janeiro, Brazil.

This study aims to describe the prevalence, distribution, and factors associated with soil-transmitted helminthiases (STHs) in rural localities in Piaui, Brazil. Two cross-sectional surveys (n=605 subjects; 172 families) were carried out in order to obtain socio-demographic, anthropometric, spatial and parasitological data. Parasites were evaluated using Kato-Katz and centrifugal sedimentation techniques. Read More

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July 2018
7 Reads

-Shift Detection of Dog-Derived and .

Biomed Res Int 2018 13;2018:7617094. Epub 2018 May 13.

Guangdong Provincial Zoonosis Prevention and Control Key Laboratory, College of Veterinary Medicine, South China Agricultural University, Guangzhou 510542, China.

To develop a -shift method for detection of dog-derived and three sets of primers were designed based on three SNPs (ITS71, ITS197, and ITS296) of their internal transcribed spacer 1 (ITS1) sequences. The detection effect of the -shift was assessed through the stability, sensitivity, accuracy test, and clinical detection. The results showed that these three sets of primers could distinguish accurately between and . Read More

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October 2018
1 Read

In vivo and in vitro studies of Cry5B and nicotinic acetylcholine receptor agonist anthelmintics reveal a powerful and unique combination therapy against intestinal nematode parasites.

PLoS Negl Trop Dis 2018 05 18;12(5):e0006506. Epub 2018 May 18.

Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA, United States of America.

Background: The soil-transmitted nematodes (STNs) or helminths (hookworms, whipworms, large roundworms) infect the intestines of ~1.5 billion of the poorest peoples and are leading causes of morbidity worldwide. Only one class of anthelmintic or anti-nematode drugs, the benzimidazoles, is currently used in mass drug administrations, which is a dangerous situation. Read More

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May 2018
2 Reads

Bacillus thuringiensis Cry5B protein as a new pan-hookworm cure.

Int J Parasitol Drugs Drug Resist 2018 08 4;8(2):287-294. Epub 2018 May 4.

Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA. Electronic address:

Hookworms are intestinal nematode parasites that infect nearly half a billion people and are globally one of the most important contributors to iron-deficiency anemia. These parasites have significant impacts in developing children, pregnant women and working adults. Of all the soil-transmitted helminths or nematodes (STNs), hookworms are by far the most important, with disease burdens conservatively estimated at four million DALYs (Disability-Adjusted Life Years) and with productivity losses of up to US$139 billion annually. Read More

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August 2018
19 Reads

[Surveillance of soil-borne nematodiasis in population in Hefei City, 2012-2015].

Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi 2018 Feb;30(2):208-210

Heifei Institute of Endemic Diseases, Anhui Province, Hefei 238000, China.

Objective: To analyze the surveillance results of soil-borne nematodiasis in Hefei City from 2012 to 2015, so as to provide the evidence formulating the Hefei "Thirteen-five" parasitic disease prevention strategy.

Methods: The population in monitoring points in Changfeng County, Lujiang City and Chaohu County were investigated for , and hookworm infections with Kato-Katz technique every year from 2012 to 2015, and the children aged less than 6 years were checked for infection by using the cellophane tape method.

Results: A total of 12 496 people were investigated from 2012 to 2015, the number of infections was 84, and among them, the number of hookworm infection was the most (70 cases) and the number of was the least (3 cases). Read More

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February 2018
2 Reads

[Survey and analysis of major human parasitic diseases in Chongqing City].

Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi 2018 Mar;30(2):194-199

Chongqing Center for Disease Control and Prevention, Chongqing 400042, China.

Objective: To investigate the epidemic of major human parasitic diseases in Chongqing City, so as to provide a reference for developing prevention and control strategies.

Methods: According to the unified methods formulated by the national investigation scheme and stratified cluster random sampling, 36 rural pilots and 50 urban pilots were selected in Chongqing City. The number of the objects investigated in individual pilot was defined over 250. Read More

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March 2018
2 Reads

Hookworm Secreted Extracellular Vesicles Interact With Host Cells and Prevent Inducible Colitis in Mice.

Front Immunol 2018 30;9:850. Epub 2018 Apr 30.

Centre for Biodiscovery and Molecular Development of Therapeutics, Australian Institute of Tropical Health and Medicine, James Cook University, Cairns, QLD, Australia.

Gastrointestinal (GI) parasites, hookworms in particular, have evolved to cause minimal harm to their hosts, allowing them to establish chronic infections. This is mediated by creating an immunoregulatory environment. Indeed, hookworms are such potent suppressors of inflammation that they have been used in clinical trials to treat inflammatory bowel diseases (IBD) and celiac disease. Read More

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April 2018
7 Reads

Prevalence of Strongyloides stercoralis infection and other soil-transmitted helminths by cross-sectional survey in a rural community in Gisagara District, Southern Province, Rwanda.

Trans R Soc Trop Med Hyg 2018 Mar;112(3):97-102

Department of Internal Medicine, School of Medicine and Pharmacy, College of Medicine and Health Sciences, University of Rwanda, Huye, Rwanda.

Background: Strongyloides stercoralis is one of the most neglected tropical diseases. Sparse, dated central African and Rwandan data on seroprevalence are available to guide public health efforts and clinical care.

Methods: In February 2016 we conducted a community-based cross-sectional study among 539 asymptomatic participants in a rural area in the Gisagara District, Southern Province, Rwanda. Read More

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March 2018
3 Reads

Efficacy and safety of co-administered ivermectin plus albendazole for treating soil-transmitted helminths: A systematic review, meta-analysis and individual patient data analysis.

PLoS Negl Trop Dis 2018 04 27;12(4):e0006458. Epub 2018 Apr 27.

Swiss Tropical and Public Health Institute, Basel, Switzerland.

Background: The soil-transmitted helminths (STH), Ascaris lumbricoides, Trichuris trichiura and hookworms, infect 1.5 billion people worldwide and cause an estimated burden of 3.3 million disability-adjusted life years (DALYs). Read More

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April 2018
2 Reads

Gastrointestinal helminths of gray wolves (Canis lupus lupus) from Sweden.

Parasitol Res 2018 Jun 25;117(6):1891-1898. Epub 2018 Apr 25.

Section for Organismal Biology, Department of Plant and Environmental Sciences, Faculty of Science, University of Copenhagen, Thorvaldsensvej 40, DK-1871, Frederiksberg C, Denmark.

As the Scandinavian wolf population is limited in size, it is only rarely subject to systematic studies on its disease biology, especially gastrointestinal parasites. Therefore, this study aims to describe the prevalence of gastrointestinal helminths of gray wolves hunted on a limited license as a part of a wildlife management program. Helminths of 20 wolves were examined post mortem by macroscopy and coprology. Read More

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June 2018
2 Reads