6,143 results match your criteria Hookworm


Prevalence, infection intensity and associated factors of soil transmitted helminths among primary school children in Gurage zone, South Central Ethiopia: a cross-sectional study design.

BMC Res Notes 2019 Apr 16;12(1):231. Epub 2019 Apr 16.

Department of Medical Laboratory Science, College of Medicine and Health Sciences, Wolkite University, P.O. Box 07, Wolkite, Ethiopia.

Objective: The aim of this study was to determine the prevalence of soil transmitted helminthes among primary school children. School based cross-sectional study design was employed. A total of six hundred study subjects were selected by a multistage sampling method. Read More

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http://dx.doi.org/10.1186/s13104-019-4254-8DOI Listing

Parasitism Elicits a Stress Response That Allocates Resources for Immune Function in South American Fur Seals (Arctocephalus australis).

Physiol Biochem Zool 2019 May/Jun;92(3):326-338

Parasites can cause chronic stress in some animal species, and this type of stress response has been associated with adverse consequences for the host. In order to know whether parasitism elicited a stress response associated with decreased host fitness, hookworm (Uncinaria sp.) infection was studied in a colony of South American fur seals (Arctocephalus australis) in which hookworms infect nearly all pups born in a reproductive season. Read More

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http://dx.doi.org/10.1086/702960DOI Listing

Should monkeys wash their hands and feet: A pilot-study on sources of zoonotic parasite exposure.

One Health 2019 Jun 16;7:100088. Epub 2019 Mar 16.

One Health Center for Zoonoses and Tropical Veterinary Medicine, Ross University School of Veterinary Medicine, P.O. Box 334, Basseterre, St.Kitts and Nevis.

Human exposure to zoonotic parasites via contaminated soil is a much studied area. Less research has been performed on exposure via contact with animals and surfaces such as picnic tables with which infected animals might be in contact. On St. Read More

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http://dx.doi.org/10.1016/j.onehlt.2019.100088DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434333PMC

Effect of integrated control intervention on soil-transmitted helminth infections in Jiangxi province in southeast China.

Acta Trop 2019 Apr 2;194:148-154. Epub 2019 Apr 2.

Jiangxi Provincial Institute of Parasitic Diseases, Nanchang 330096, China. Electronic address:

Soil transmitted helminths (STHs) burden was enormous in China several decades ago, however, rigorous control efforts have been successful with appreciable reduction in diseases burden. Here, we assessed provincial-level data derived from cross sectional surveys, executed in 1989, 2002 and 2014, on the prevalence of STHs among populations in Jiangxi province, China. This study, also, reported STHs integrated control intervention aimed at reducing STHs transmission and worm burden among population at county-level. Read More

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http://dx.doi.org/10.1016/j.actatropica.2019.04.001DOI Listing
April 2019
1 Read

Prevalence and clinical outcomes of Plasmodium falciparum and intestinal parasitic infections among children in Kiryandongo refugee camp, mid-Western Uganda: a cross sectional study.

BMC Infect Dis 2019 Apr 1;19(1):295. Epub 2019 Apr 1.

Department of Biology, Faculty of Science and Education, Busitema University, Tororo, Uganda.

Background: The prevalence of Plasmodium falciparum and Intestinal Parasitic Infections (IPIs) - with the corresponding pathogenesis among children remain uncertain. This study aimed at determining the prevalence and the outcomes (including anaemia) of the respective infections and co-infections. Anaemia is a condition in which the number of red blood cells transporting oxygen to the various body parts is not sufficient to meet the needs of the body. Read More

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http://dx.doi.org/10.1186/s12879-019-3939-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444856PMC
April 2019
1 Read

Efficacy and safety of ivermectin and albendazole co-administration in school-aged children and adults infected with Trichuris trichiura: study protocol for a multi-country randomized controlled double-blind trial.

BMC Infect Dis 2019 Mar 18;19(1):262. Epub 2019 Mar 18.

Swiss Tropical and Public Health Institute, Basel, Switzerland.

Background: Soil-transmitted helminthiasis affects almost 2 billion people worldwide in tropical climates. Preventive chemotherapy, using the benzimidazoles (albendazole and mebendazole) is the current main recommended control strategy. Nevertheless, there is limited efficacy of these drugs against hookworm infection and, to a greater extent, against trichuriasis. Read More

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http://dx.doi.org/10.1186/s12879-019-3882-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421712PMC
March 2019
1 Read
2.613 Impact Factor

Epidemiology of soil transmitted helminth and Strongyloides stercoralis infections in remote rural villages of Ranomafana National Park, Madagascar.

Pathog Glob Health 2019 Mar 17:1-7. Epub 2019 Mar 17.

e Global Health Institute , Stony Brook University , Stony Brook , NY , USA.

Soil-transmitted helminth (STH) infections carry the highest number of disability adjusted life years among all neglected tropical diseases, disproportionately affecting low-income countries such as Madagascar.  This study describes the epidemiology of STH and S. stercoralis infections in twelve remote villages surrounding Ranomafana National Park (RNP), Ifanadiana, Madagascar. Read More

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http://dx.doi.org/10.1080/20477724.2019.1589927DOI Listing
March 2019
1 Read

Drug Combinations Against Soil-Transmitted Helminth Infections.

Adv Parasitol 2019 7;103:91-115. Epub 2018 Sep 7.

Swiss Tropical and Public Health Institute, Basel, Switzerland; University of Basel, Basel, Switzerland.

The soil-transmitted helminths (STHs), Ascaris lumbricoides, hookworm and Trichuris trichiura are common in areas with warm and moist climates with little access to adequate water, sanitation, and hygiene affecting the poorest populations. The current control strategy of the World Health Organization is preventive chemotherapy (PC), i.e. Read More

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http://dx.doi.org/10.1016/bs.apar.2018.08.002DOI Listing
September 2018
1 Read

Combination Anthelmintic Treatment for Persistent Ova Shedding in Greyhounds.

J Am Anim Hosp Assoc 2019 May/Jun;55(3):160-166. Epub 2019 Mar 14.

From the Department of Veterinary Preventive Medicine (L.B.H., A.M.), and Department of Veterinary Clinical Sciences (L.M.M., A.R., E.V.), College of Veterinary Medicine, The Ohio State University, Columbus, Ohio.

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http://jaaha.org/doi/10.5326/JAAHA-MS-6904
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http://dx.doi.org/10.5326/JAAHA-MS-6904DOI Listing
March 2019
4 Reads

The Effectiveness of Triple Dose Albendazole in Treating Soil Transmitted Helminths Infection.

J Parasitol Res 2019 4;2019:6438497. Epub 2019 Feb 4.

Department of Microbiology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia.

Soil transmitted helminths (STH) infection is a major health problem in tropical countries such as Indonesia. Albendazole is an effective and widely used anthelmintic agent to treat STH; however, it is not effective towards and its effectiveness varies between populations. Hence, we conducted a study to determine the effectiveness of triple dose albendazole in children of Perobatang village, Southwest Sumba, Indonesia. Read More

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http://dx.doi.org/10.1155/2019/6438497DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378773PMC
February 2019
1 Read

Resolving "worm wars": An extended comparison review of findings from key economics and epidemiological studies.

PLoS Negl Trop Dis 2019 03 7;13(3):e0006940. Epub 2019 Mar 7.

Center for Health and Biosciences, James A Baker III Institute for Public Policy, Rice University, Houston, Texas, United States of America.

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http://dx.doi.org/10.1371/journal.pntd.0006940DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405048PMC
March 2019
7 Reads

Establishment of a Tm-shift Method for Detection of Cat-Derived Hookworms.

Korean J Parasitol 2019 Feb 26;57(1):9-15. Epub 2019 Feb 26.

Guangdong Provincial Zoonosis Prevention and Control Key Laboratory, College of Veterinary Medicine, South China Agricultural University, Guangzhou 510542, P. R. China.

Melting temperature shift (Tm-shift) is a new detection method that analyze the melting curve on real-time PCR thermocycler using SYBR Green I fluorescent dye. To establish a Tm-shift method for the detection of Ancylostoma ceylanicum and A. tubaeforme in cats, specific primers, with GC tail of unequal length attached to their 5 ́ end, were designed based on 2 SNP loci (ITS101 and ITS296) of the internal transcribed spacer 1 (ITS1) sequences. Read More

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http://dx.doi.org/10.3347/kjp.2019.57.1.9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409220PMC
February 2019
2 Reads

Hookworm-related cutaneous larva migrans of the penis successfully treated with topical ivermectin.

Pediatr Dermatol 2019 Mar 3. Epub 2019 Mar 3.

Department of Pathophysiology and Transplantation, Università degli Studi di Milano, I.R.C.C.S. Foundation, Cà Granda Ospedale Maggiore Policlinico, Milan, Italy.

Hookworm-related cutaneous larva migrans is an infestation of the skin caused by nematodes. Involvement of genitals is extremely rare. We report the case of a child with this infestation on the penis who cleared rapidly with topical ivermectin. Read More

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http://dx.doi.org/10.1111/pde.13789DOI Listing
March 2019
6 Reads

Parasitic infections during pregnancy need not affect infant antibody responses to early vaccination against Streptococcus pneumoniae, diphtheria, or Haemophilus influenzae type B.

PLoS Negl Trop Dis 2019 02 28;13(2):e0007172. Epub 2019 Feb 28.

Division of Infectious Diseases, Department of Pediatrics, Lucille Packard Children's Hospital at Stanford School of Medicine, Stanford, California, United States of America.

Background: Globally, vaccine-preventable diseases remain a significant cause of early childhood mortality despite concerted efforts to improve vaccine coverage. One reason for impaired protection may be the influence of prenatal exposure to parasitic antigens on the developing immune system. Prior research had shown a decrease in infant vaccine response after in utero parasite exposure among a maternal cohort without aggressive preventive treatment. Read More

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http://dx.plos.org/10.1371/journal.pntd.0007172
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http://dx.doi.org/10.1371/journal.pntd.0007172DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413956PMC
February 2019
10 Reads

Household socio-economic position and individual infectious disease risk in rural Kenya.

Sci Rep 2019 Feb 27;9(1):2972. Epub 2019 Feb 27.

International Livestock Research Institute, Old Naivasha Road, PO BOX 30709, 00100, Nairobi, Kenya.

The importance of household socio-economic position (SEP) in shaping individual infectious disease risk is increasingly recognised, particularly in low income settings. However, few studies have measured the extent to which this association is consistent for the range of pathogens that are typically endemic among the rural poor in the tropics. This cross-sectional study assessed the relationship between SEP and human infection within a single community in western Kenya using a set of pathogens with diverse transmission routes. Read More

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http://www.nature.com/articles/s41598-019-39375-z
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http://dx.doi.org/10.1038/s41598-019-39375-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393457PMC
February 2019
5 Reads

Molecular identification of zoonotic hookworms in dogs from four counties of Kenya.

J Helminthol 2019 Feb 28:1-8. Epub 2019 Feb 28.

Parasitology Unit,University of Hohenheim,Stuttgart,Germany.

All canine hookworms are known to be zoonotic, causing infections ranging from transient skin irritations to prolonged 'creeping eruptions', eosinophilic enteritis and even patent intestinal infections. There is little information on canine hookworm species and their public health significance in sub-Saharan Africa. This study determined the prevalence and species of hookworms in dogs from different climatic zones of Kenya. Read More

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http://dx.doi.org/10.1017/S0022149X1900018XDOI Listing
February 2019

Intestinal helminth infections in HIV-infected patients in Savannakhet after establishment of an HIV registration network in Lao People's Democratic Republic.

Trop Med Health 2019 11;47:14. Epub 2019 Feb 11.

1Laboratory of Hematoimmunology, Graduate School of Health Sciences, University of the Ryukyus, Nishihara, Okinawa Japan.

Background: In Lao People's Democratic Republic (PDR), which borders China, Vietnam, Cambodia, Thailand, and Myanmar, the number of HIV-infected patients has increased in recent years. HIV-infected patients diagnosed in Lao PDR are enrolled in a registration network and receive antiretroviral therapy (ART) covered by governmental financial support. Based on the registration network, we investigated intestinal helminth infections and coinfection with HTLV-1 in HIV-infected patients treated with an early intervention using ART in Lao PDR. Read More

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http://dx.doi.org/10.1186/s41182-019-0142-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371529PMC
February 2019

Molecular identification of hookworm isolates from stray dogs, humans and selected wildlife from South Africa.

J Helminthol 2019 Feb 21:1-9. Epub 2019 Feb 21.

School of Life Sciences,College of Agriculture, Engineering and Science,University of KwaZulu-Natal,Westville Campus,Durban 4001,South Africa.

There is a paucity of information on hookworm species in humans, domestic animals and wildlife in southern Africa. Our study aimed to identify hookworm species from stray dogs, humans, and selected wildlife from South Africa. A total of 356 faecal samples were screened for the presence of hookworm-like eggs and subsequently coproculture from the positive samples was carried out to obtain larvae. Read More

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http://dx.doi.org/10.1017/S0022149X19000130DOI Listing
February 2019

Good manufacturing practices of minimally processed vegetables reduce contamination with pathogenic microorganisms.

Rev Inst Med Trop Sao Paulo 2019 Feb 14;61:e14. Epub 2019 Feb 14.

Universidade de Brasília, Faculdade de Medicina, Laboratório de Parasitologia Médica e Biologia de Vetores, Brasília, Distrito Federal, Brazil.

Consumption of ready-to-eat (RTE) vegetables is quick, easy and healthy, especially when eaten without cooking. However, they might be a source of foodborne pathogenic microorganisms. The objective of this study was to evaluate the microbiological and parasitological contamination of fresh RTE vegetables produced in agroindustries in the Federal District of Brazil (FD), and to correlate contamination with good manufacturing practices (GMP). Read More

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http://dx.doi.org/10.1590/S1678-9946201961014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376928PMC
February 2019
3 Reads

Isolation and characterization of a naturally occurring multidrug-resistant strain of the canine hookworm, Ancylostoma caninum.

Int J Parasitol 2019 Apr 14;49(5):397-406. Epub 2019 Feb 14.

Department of Microbiology, Immunology, and Tropical Medicine, Ross Hall, 2300 I St. NW, The George Washington University, Washington, DC 20052, USA. Electronic address:

Soil-transmitted nematodes infect over a billion people and place several billion more at risk of infection. Hookworm disease is the most significant of these soil-transmitted nematodes, with over 500 million people infected. Hookworm infection can result in debilitating and sometimes fatal iron-deficiency anemia, which is particularly devastating in children and pregnant women. Read More

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http://dx.doi.org/10.1016/j.ijpara.2018.12.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456372PMC
April 2019
2 Reads

Soil-transmitted helminth reinfection four and six months after mass drug administration: results from the delta region of Myanmar.

PLoS Negl Trop Dis 2019 02 15;13(2):e0006591. Epub 2019 Feb 15.

Department of Infectious Disease Epidemiology, School of Public Health, Faculty of Medicine, Imperial College London, London, United Kingdom.

Background: Mass drug administration (MDA), targeted at school-aged children (SAC) is the method recommended by the World Health Organization for the control of morbidity induced by soil-transmitted helminth (STH) infection in endemic countries. However, MDA does not prevent reinfection between treatment rounds and research suggests that only treating SAC will not be sufficient to bring prevalence to low levels and possibly interrupt transmission of STH. In countries with endemic infection, such as Myanmar, the coverage, who is targeted, and rates of reinfection will determine how effective MDA is in suppressing transmission in the long-term. Read More

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http://dx.doi.org/10.1371/journal.pntd.0006591DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395004PMC
February 2019

Ovicidal and larvicidal effects of extracts from leaves of Andrographis paniculata (Burm. f.) Wall.ex Nees against field isolates of human hookworm (Ancylostoma duodenale).

J Ethnopharmacol 2019 May 11;235:489-500. Epub 2019 Feb 11.

Department of Biological Science, Adamawa State University, P.M.B. 25, Mubi, Nigeria. Electronic address:

Ethnopharmacological Relevance: The whole plant of Andrographis paniculata (Burm. f.) Wall. Read More

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http://dx.doi.org/10.1016/j.jep.2019.02.021DOI Listing
May 2019
15 Reads
2.998 Impact Factor

Pharmacokinetics of Albendazole, Albendazole Sulfoxide, and Albendazole Sulfone Determined from Plasma, Blood, Dried-Blood Spots, and Mitra Samples of Hookworm-Infected Adolescents.

Antimicrob Agents Chemother 2019 Apr 27;63(4). Epub 2019 Mar 27.

Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland

Albendazole is an effective anthelmintic intensively used for decades. However, profound pharmacokinetic (PK) characterization is missing in children, the population mostly affected by helminth infections. Blood microsampling would facilitate PK studies in pediatric populations but has not been applied to quantify albendazole's disposition. Read More

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http://dx.doi.org/10.1128/AAC.02489-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437472PMC
April 2019
11 Reads

Genetic Markers of Benzimidazole Resistance among Human Hookworms () in Kintampo North Municipality, Ghana.

Am J Trop Med Hyg 2019 Feb;100(2):351-356

Yale Partnerships for Global Health, Department of Pediatrics, Yale School of Medicine, New Haven, Connecticut.

Hookworm infection causes anemia, malnutrition, and growth delay, especially in children living in sub-Saharan Africa. The World Health Organization recommends periodic mass drug administration (MDA) of anthelminthics to school-age children (SAC) as a means of reducing morbidity. Recently, questions have been raised about the effectiveness of MDA as a global control strategy for hookworms and other soil-transmitted helminths (STHs). Read More

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http://dx.doi.org/10.4269/ajtmh.18-0727DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367626PMC
February 2019
2.699 Impact Factor

Albendazole resistance induced in Ancylostoma ceylanicum is not due to single-nucleotide polymorphisms (SNPs) at codons 167, 198, or 200 of the beta-tubulin gene, indicating another resistance mechanism.

Parasitol Res 2019 Mar 29;118(3):837-849. Epub 2019 Jan 29.

Departamento de Parasitologia, L4 237, Laboratório de Parasitologia Molecular, Universidade Federal de Minas Gerais, Instituto de Ciências Biológicas, Avenida Presidente Antônio Carlos, 6627, Pampulha, CEP 31270-901, Belo Horizonte, Minas Gerais, Brazil.

Mass drug administration has been implicated as the major cause of drug resistance in nematodes of ruminants. Single-nucleotide polymorphisms (SNPs) at codons 167, 198, and 200 of the beta-tubulin isotype 1 gene are associated with albendazole resistance mechanisms. Although drug resistance is suspected to occur in nematodes of the same order, at present, there is no evidence of a strong correlation between these canonical SNPs and albendazole resistance in hookworms. Read More

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http://link.springer.com/10.1007/s00436-019-06218-9
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http://dx.doi.org/10.1007/s00436-019-06218-9DOI Listing
March 2019
1 Read

Epidemiology of Hookworm Infection in the School-age Children: A Comparative Cross-sectional Study.

Iran J Parasitol 2018 Oct-Dec;13(4):560-566

Dept. of Epidemiology and Biostatistics, University of Bahir Dar, Bahir Dar, Ethiopia.

Background: Globally more than 740 million peoples are infected with hookworm. In sub-Saharan Africa, approximately 200 million people have been infected with hookworm, 90 million of them were children. The objective of this study was to identify the prevalence and determinant factors of hookworm infection in urban and rural school-age children's. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348213PMC
January 2019
1 Read
0.872 Impact Factor

China's shifting neglected parasitic infections in an era of economic reform, urbanization, disease control, and the Belt and Road Initiative.

PLoS Negl Trop Dis 2019 01 24;13(1):e0006946. Epub 2019 Jan 24.

Departments of Pediatrics and Molecular Virology and Microbiology, National School of Tropical Medicine, Baylor College of Medicine, Houston, Texas, United States of America.

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http://dx.doi.org/10.1371/journal.pntd.0006946DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345419PMC
January 2019
19 Reads

Gene structure and expression patterns of Acdaf-1, a TGF-β type I receptor in Ancylostoma caninum.

Parasitol Res 2019 Mar 22;118(3):817-828. Epub 2019 Jan 22.

State Key Laboratory of Cellular Stress Biology, School of Life Science, Xiamen University, Xiamen, 361005, Fujian, People's Republic of China.

The components of the transforming growth factor β (TGF-β) signaling pathway in parasitic nematodes remain unknown. In this research, a type I receptor for TGF-β was isolated from the hookworm Ancylostoma caninum. The new gene was designated as Acdaf-1, a Caenorhabditis elegans daf-1 homolog. Read More

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http://dx.doi.org/10.1007/s00436-018-6142-xDOI Listing

Hookworm-Derived Metabolites Suppress Pathology in a Mouse Model of Colitis and Inhibit Secretion of Key Inflammatory Cytokines in Primary Human Leukocytes.

Infect Immun 2019 Apr 25;87(4). Epub 2019 Mar 25.

Centre for Biodiscovery and Molecular Development of Therapeutics, Australian Institute of Tropical Health and Medicine, James Cook University, Cairns, Australia

Iatrogenic hookworm therapy shows promise for treating disorders that result from a dysregulated immune system, including inflammatory bowel disease (IBD). Using a murine model of trinitrobenzenesulfonic acid-induced colitis and human peripheral blood mononuclear cells, we demonstrated that low-molecular-weight metabolites derived from both somatic extracts (LMWM-SE) and excretory-secretory products (LMWM-ESP) of the hookworm, , display anti-inflammatory properties. Administration to mice of LMWM-ESP as well as sequentially extracted fractions of LMWM-SE using both methanol (SE-MeOH) and hexane-dichloromethane-acetonitrile (SE-HDA) resulted in significant protection against T cell-mediated immunopathology, clinical signs of colitis, and impaired histological colon architecture. Read More

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http://dx.doi.org/10.1128/IAI.00851-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434117PMC
April 2019
11 Reads
3.731 Impact Factor

Analysis of Schistosomiasis and soil-transmitted helminths mixed infections among pupils in Enugu State, Nigeria: Implications for control.

Infect Dis Health 2019 Jan 12. Epub 2019 Jan 12.

Department of Parasitology and Entomology, Faculty of Biosciences, Nnamdi Azikiwe University, P.M.B 5025, Awka, Anambra State, Nigeria. Electronic address:

Background: Schistosomiasis and Soil-transmitted helminthiasis cause considerable morbidity and mortality in developing countries, especially among children. To this end it, a cross-sectional survey to determine the pattern of Schistosomiasis and Soil-transmitted helminthiasis co-infection was undertaken among primary school pupils in Oduma Community in Enugu State, Nigeria.

Methods: Fresh urine and stool samples were collected from pupils. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S24680451183016
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http://dx.doi.org/10.1016/j.idh.2018.12.003DOI Listing
January 2019
8 Reads

Substrate type and age are risk factors for gastrointestinal parasitism in greyhound kennels.

Vet Parasitol 2019 Jan 7;265:7-14. Epub 2018 Dec 7.

School of Veterinary and Life Sciences, Murdoch University, South Street, Perth 6150 Australia; Andersons Moores Veterinary Specialists, The Granary, Bunstead Barns, Poles Ln, Hursley, UK.

The control of parasitic infections is particularly challenging in environments that are conducive to the maintenance of parasite lifecycles, such as the greyhound kennel, where the long-term breeding and rearing of dogs is common. The prevalence of gastrointestinal (GI) parasites within the Australian greyhound population has never previously been assessed, which seriously constrains the implementation of effective control measures. The aims of this study were to determine the prevalence and risk factors for GI parasites in Australian greyhounds, identify parasites which may be detrimental to the health and performance of dogs, and evaluate the likelihood of zoonotic transmission to kennel staff. Read More

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http://dx.doi.org/10.1016/j.vetpar.2018.11.013DOI Listing
January 2019
2 Reads

Intestinal hookworm infestation causing chronic anaemia.

BMJ Case Rep 2019 Jan 10;12(1). Epub 2019 Jan 10.

Digestive and Interventional Endoscopy Unit, Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda, Milano, Italy.

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http://casereports.bmj.com/lookup/doi/10.1136/bcr-2018-22812
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http://dx.doi.org/10.1136/bcr-2018-228120DOI Listing
January 2019
9 Reads

Overview of Deep Learning in Gastrointestinal Endoscopy.

Gut Liver 2019 Jan 11. Epub 2019 Jan 11.

Department of Internal Medicine, Kyung Hee University School of Medicine, Seoul, Korea.

Artificial intelligence is likely to perform several roles currently performed by humans, and the adoption of artificial intelligence-based medicine in gastroenterology practice is expected in the near future. Medical image-based diagnoses, such as pathology, radiology, and endoscopy, are expected to be the first in the medical field to be affected by artificial intelligence. A convolutional neural network, a kind of deep-learning method with multilayer perceptrons designed to use minimal preprocessing, was recently reported as being highly beneficial in the field of endoscopy, including esophagogastroduodenoscopy, colonoscopy, and capsule endoscopy. Read More

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http://www.gutnliver.org/journal/view.html?doi=10.5009/gnl18
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http://dx.doi.org/10.5009/gnl18384DOI Listing
January 2019
21 Reads

Antagonistic effects of Plasmodium-helminth co-infections on malaria pathology in different population groups in Côte d'Ivoire.

PLoS Negl Trop Dis 2019 01 10;13(1):e0007086. Epub 2019 Jan 10.

Swiss Tropical and Public Health Institute, Basel, Switzerland.

Introduction: Plasmodium spp. and helminths are co-endemic in many parts of the tropics; hence, co-infection is a common phenomenon. Interactions between Plasmodium and helminth infections may alter the host's immune response and susceptibility and thus impact on morbidity. Read More

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http://dx.doi.org/10.1371/journal.pntd.0007086DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343929PMC
January 2019
6 Reads

Prevalence of parasitic contamination of raw vegetables in Nakhon Si Thammarat province, southern Thailand.

BMC Public Health 2019 Jan 8;19(1):34. Epub 2019 Jan 8.

Department of Tropical Pathology, Faculty of Tropical Medicine, Mahidol University, Bangkok, 10400, Thailand.

Background: Soil-transmitted helminth (STH) infections are major public health problems in poor and developing countries that require fecal contamination of the environment for transmission. The consumption of raw vegetables without proper washing is one of the main routes of intestinal parasite acquisition. Therefore, this study was designed to detect the prevalence of intestinal parasitic contamination in commonly consumed raw vegetables sold in three central open-air markets in Nakhon Si Thammarat province, southern Thailand. Read More

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http://dx.doi.org/10.1186/s12889-018-6358-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323832PMC
January 2019
3 Reads

Human Hookworm Infection Enhances Mycobacterial Growth Inhibition and Associates With Reduced Risk of Tuberculosis Infection.

Front Immunol 2018 14;9:2893. Epub 2018 Dec 14.

Nuffield Department of Medicine, The Jenner Institute, University of Oxford, Oxford, United Kingdom.

Soil-transmitted helminths and frequently coincide geographically and it is hypothesized that gastrointestinal helminth infection may exacerbate tuberculosis (TB) disease by suppression of Th1 and Th17 responses. However, few studies have focused on latent TB infection (LTBI), which predominates globally. We performed a large observational study of healthy adults migrating from Nepal to the UK ( = 645). Read More

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http://dx.doi.org/10.3389/fimmu.2018.02893DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302045PMC
December 2018
3 Reads

Intestinal parasitic infestations and anemia among urban female school children in Kancheepuram district, Tamil Nadu.

J Family Med Prim Care 2018 Nov-Dec;7(6):1395-1400

Department of Community Medicine, Sree Balaji Medical College and Hospital, Bharath Institute of Higher Education and Research, Chrompet, Chennai, Tamil Nadu, India.

Introduction: In India, intestinal parasitic infection and anemia remain the most important cause of morbidity especially among the adolescent school children due to lack of awareness of personal hygiene practices, leading to intestinal parasite infections which could in turn lead to anemia.

Aim: This study was conducted with the aim to find out the prevalence of intestinal parasitic infection and anemia among adolescent female school children in an urban area of Tamil Nadu.

Materials And Method: This descriptive cross-sectional study was done among adolescent female school children in Anakaputhur area of Kancheepuram district. Read More

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http://www.jfmpc.com/text.asp?2018/7/6/1395/246524
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http://dx.doi.org/10.4103/jfmpc.jfmpc_89_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293916PMC
January 2019
8 Reads

Helminth infections of wild European gray wolves (Canis lupus Linnaeus, 1758) in Lower Saxony, Germany, and comparison to captive wolves.

Parasitol Res 2019 Feb 4;118(2):701-706. Epub 2019 Jan 4.

Institute for Parasitology, Centre for Infection Medicine, University of Veterinary Medicine Hannover, Bünteweg 17, 30159, Hannover, Germany.

This study aimed to investigate the endoparasite fauna of wild European gray wolves, which are currently recolonizing Germany. In total, 69 fecal samples of wild wolves were collected in Lower Saxony, Germany, from 2013 to 2015, analyzed by the sedimentation-flotation and McMaster techniques and compared to previous results on captive European Gray wolves living in zoological gardens in Germany. In addition to coproscopy, taeniid-positive samples from wild as well as captive wolves were differentiated by amplification and sequencing of small subunit ribosomal RNA (SSU rRNA) and NADH dehydrogenase 1 (nad1) gene fragments. Read More

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http://dx.doi.org/10.1007/s00436-018-6181-3DOI Listing
February 2019
1 Read

Health, financial, and education gains of investing in preventive chemotherapy for schistosomiasis, soil-transmitted helminthiases, and lymphatic filariasis in Madagascar: A modeling study.

PLoS Negl Trop Dis 2018 12 27;12(12):e0007002. Epub 2018 Dec 27.

Department of Global Health and Population, Harvard T.H. Chan School of Public Health, Boston MA, United States of America.

Background: Neglected tropical diseases (NTDs) account for a large disease burden in sub-Saharan Africa. While the general cost-effectiveness of NTD interventions to improve health outcomes has been assessed, few studies have also accounted for the financial and education gains of investing in NTD control.

Methods: We built on extended cost-effectiveness analysis (ECEA) methods to assess the health gains (e. Read More

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http://dx.plos.org/10.1371/journal.pntd.0007002
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http://dx.doi.org/10.1371/journal.pntd.0007002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307713PMC
December 2018
15 Reads

Deworming in non-pregnant adolescent girls and adult women: a systematic review and meta-analysis.

Syst Rev 2018 12 20;7(1):239. Epub 2018 Dec 20.

Bruyère Research Institute, Bruyère, 310 - 85 Primrose Avenue E, Ottawa, ON, K1R 7G5, Canada.

Background: The impact of deworming on parasite load, nutritional status and other health outcomes of non-pregnant adolescent girls and adult women is uncertain.

Methods: MEDLINE, EMBASE, CINAHL, the Cochrane Central Register of Controlled Trials, the WHO International Clinical Trials Registry Platform, the Cochrane Database of Systematic Reviews and Food and Technology Abstracts databases were searched until 24 September 2018. Studies were included if they were randomised controlled trials (RCTs), controlled before and after studies or interrupted time studies comparing deworming with no intervention or placebo in non-pregnant adolescent girls and women 10 to 49 years old. Read More

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https://systematicreviewsjournal.biomedcentral.com/articles/
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http://dx.doi.org/10.1186/s13643-018-0859-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300900PMC
December 2018
9 Reads

[Investigation on intestinal nematode infections and their risk factors in Shanpo Sub-district, Jiangxia District, Wuhan City].

Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi 2018 May;30(5):567-570

Department of Human Parasitology, School of Basic Medical Sciences, Wuhan University, Wuhan 430071, China.

Objective: To investigate the infection status of intestinal nematodes and their risk factors in rural residents of Jiangxia District, Wuhan City, so as to provide the reference for the establishment of targeted prevention and control measures.

Methods: According to the requirements of cross-sectional study of the national human key parasitic diseases, the residents in Shanpo Sub-district, Jiangxia District were randomly selected as the objects for the investigation of the infection status of , hookworm and . A questionnaire survey was performed simultaneously. Read More

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http://dx.doi.org/10.16250/j.32.1374.2017159DOI Listing
May 2018
13 Reads

Inflammatory and regulatory CCL and CXCL chemokine and cytokine cellular responses in patients with patent Mansonella perstans filariasis.

Clin Exp Immunol 2019 Apr 13;196(1):111-122. Epub 2019 Jan 13.

National Institute of Hygiene, Onchocerciasis Reference Laboratory, Sokodé, Togo.

Mansonella perstans (Mp) filariasis is present in large populations in sub-Saharan Africa, and to what extent patent Mp infection modulates the expression of immunity in patients, notably their cellular cytokine and chemokine response profile, remains not well known. We studied the spontaneous and inducible cellular production of chemokines (C-X-C motif) ligand 9 (CXCL9) [monokine induced by interferon (IFN)-γ (MIG)], CXCL-10 [inducible protein (IP)-10], chemokine (C-C motif) ligand 24 (CCL24) (eotaxin-2), CCL22 [macrophage-derived chemokine (MDC)], CCL13 [monocyte chemotactic protein-4 (MCP-4)], CCL18 [pulmonary and activation-regulated chemokine (PARC)], CCL17 [thymus- and activation-regulated chemokine (TARC)] and interleukin (IL)-27 in mansonelliasis patients (Mp-PAT) and mansonelliasis-free controls (CTRL). Freshly isolated peripheral mononuclear blood cells (PBMC) were stimulated with helminth, protozoan and bacterial antigens and mitogen [phytohaemagglutinin (PHA)]. Read More

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http://dx.doi.org/10.1111/cei.13251DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422653PMC
April 2019
3 Reads

The burden and epidemiology of polyparasitism among rural communities in Kano State, Nigeria.

Trans R Soc Trop Med Hyg 2019 Apr;113(4):169-182

Department of Parasitology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.

Background: Parasitic infections constitute a major public health problem worldwide, particularly among underprivileged communities in developing countries including Nigeria. The present study aimed to determine the epidemiology of polyparasitism (multiple parasitic infections) among rural communities in Kano State, North Central Nigeria.

Methods: A total of 551 individuals were screened for the presence of intestinal, urogenital and blood parasites by using different diagnostic techniques. Read More

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http://dx.doi.org/10.1093/trstmh/try128DOI Listing
April 2019
1 Read
1.931 Impact Factor

Prevalence and correlates of anemia among adolescents in Nepal: Findings from a nationally representative cross-sectional survey.

PLoS One 2018 14;13(12):e0208878. Epub 2018 Dec 14.

Department of Paediatrics, the University of Melbourne, Melbourne, Australia.

Anemia is regarded as major public health problem among adolescents in Low and Middle-Income Countries (LMICs) but there is limited primary data in many countries, including Nepal. This study investigated the prevalence and correlates of anemia in a nationally representative sample of adolescents within the 2014 National Adolescent Nutrition Survey in Nepal. A total of 3780 adolescents aged 10 to 19 years were selected from a cross-sectional survey through multi-stage cluster sampling. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0208878PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294609PMC
December 2018
2 Reads

Prevalence of intestinal parasites and the absence of soil-transmitted helminths in Añatuya, Santiago del Estero, Argentina.

Parasit Vectors 2018 Dec 14;11(1):638. Epub 2018 Dec 14.

Fundación Mundo Sano, Paraguay, 1535, Buenos Aires, Argentina.

Background: Intestinal parasites (IP) have been reported in point studies from different provinces of Argentina. The presence of soil-transmitted helminths (STH) was detected in many of these studies, including varied prevalences of all five species of STH in the north were the climate is more appropriate for transmission. Nonetheless, Argentina lacks a comprehensive prevalence map of STH. Read More

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http://dx.doi.org/10.1186/s13071-018-3232-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295026PMC
December 2018

A comparison of helminth infections as assessed through coprological analysis and adult worm burdens in a wild host.

Int J Parasitol Parasites Wildl 2018 Dec 14;7(3):439-444. Epub 2018 Nov 14.

Department of Zoology, School of Natural Sciences, Trinity College Dublin, Ireland.

Coprological analysis is the most widely used diagnostic tool for helminth infection in both domestic and wild mammals. Evaluation of the efficacy of this technique is rare, due to the lack of availability of adult worm burden. Where information is available the majority of studies are in small ruminants and seldom in a wild host. Read More

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http://dx.doi.org/10.1016/j.ijppaw.2018.11.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261086PMC
December 2018

Fortification of Carica papaya fruit seeds to school meal snacks may aid Africa mass deworming programs: a preliminary survey.

BMC Complement Altern Med 2018 Dec 7;18(1):327. Epub 2018 Dec 7.

The Graduate School, Kenya Medical Research Institute, Mbagathi Road, Nairobi, P.O. BOX 54840, Kenya.

Background: Soil transmitted helminths (STHs) are among the world's neglected tropical diseases. Morbidity due to STHs is greatest in school-age children who typically have the highest burden of infection. In 2001, WHO passed a resolution for the use of large-scale mass drug administration (MDA) to deworm vulnerable children through school based programs. Read More

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https://bmccomplementalternmed.biomedcentral.com/articles/10
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http://dx.doi.org/10.1186/s12906-018-2379-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286506PMC
December 2018
7 Reads

Mitochondrial DNA reveals species composition and phylogenetic relationships of hookworms in northeastern Brazil.

Infect Genet Evol 2019 Mar 30;68:105-112. Epub 2018 Nov 30.

Laboratory of Epidemiology and Molecular Systematics, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil; Oswaldo Cruz Foundation, Teresina, Piauí, Brazil. Electronic address:

Hookworm infection persists focally in rural communities in Brazil. In this study, we analyze the mitochondrial nucleotide sequences obtained from hookworms infecting humans in order to characterize species composition and assess their genetic diversity and phylogenetic relationships. Field expeditions and cross-sectional surveys were carried out in three Brazilian municipalities from 2013 to 2017: Nossa Senhora de Nazaré (n = 605) and Teresina (n = 297), in the state of Piauí, and Russas (n = 213) in the State of Ceará. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S15671348183071
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http://dx.doi.org/10.1016/j.meegid.2018.11.018DOI Listing
March 2019
18 Reads

Efficacy and safety of ascending dosages of tribendimidine against hookworm infections in children: a randomized controlled trial.

Clin Infect Dis 2018 Nov 29. Epub 2018 Nov 29.

Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland.

Background: The global strategy to control soil-transmitted helminthiasis is mainly focused on preventive chemotherapy based on albendazole and mebendazole. We assessed the efficacy and safety of ascending tribendimidine doses against hookworm infections in African school-aged children, key information to be able to include tribendimidine in preventive deworming campaigns.

Methods: We performed a single blind randomized controlled trial in Côte d'Ivoire between June and August 2017. Read More

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http://dx.doi.org/10.1093/cid/ciy999DOI Listing
November 2018

Efficacy and safety of a new topical formulation of selamectin plus sarolaner in the treatment and control of natural infections of Ancylostoma tubaeforme and Toxocara cati in cats presented as veterinary patients in the United States.

Vet Parasitol 2018 Nov 11. Epub 2018 Nov 11.

Zoetis, Veterinary Medicine Research and Development, 333 Portage Street, Kalamazoo, MI, 49007, USA.

A new topical formulation of selamectin plus sarolaner (Revolution Plus/Stronghold Plus, Zoetis) was evaluated in the treatment and control of naturally occurring infections of Ancylostoma tubaeforme and Toxocara cati in cats presented as veterinary patients in the United States. Three thousand three hundred three (3303) cats were screened in 25 veterinary practices in 15 states and 153 hookworm-positive cats (A. tubaeforme and/or A. Read More

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http://dx.doi.org/10.1016/j.vetpar.2018.10.012DOI Listing
November 2018
3 Reads