945 results match your criteria Hipertension y Riesgo Cardiovascular[Journal]


The importance of patient perspectives in pulmonary hypertension.

Eur Respir J 2018 Dec 13. Epub 2018 Dec 13.

Pulmonary Hypertension Association, Silver Spring, MD, USA.

The assessment of objective measurement of cardiopulmonary status has helped us achieve better clinical outcomes for patients and develop new therapies through to the point of market access; however, patient surveys indicate that more can be done to improve holistic care and patient engagement. In this multidisciplinary review, we examine how clinical teams can acknowledge and embrace the individual patient's perspective, and thus improve the care for individual patients suffering from pulmonary hypertension by cultivating the importance and relevance of health-related quality of life in direct clinical care. At the individual level, patients should be provided with access to accredited specialist centres which provide a multidisciplinary approach where there is a culture focused on narrative medicine, quality of life, shared decision making and timely access to palliative care, and where there is participation in education. Read More

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December 2018

Comparative evaluation of dexmedetomidine and labetalol for attenuating hemodynamic stress responses during laparoscopic cholecystectomy in borderline hypertensive patients.

Rev Esp Anestesiol Reanim 2018 Dec 10. Epub 2018 Dec 10.

Department of Obstetrics and Gynecology, Himalayan Institute of Medical Sciences, Dehradun, Uttarakhand, India.

Objective: Various pharmacological agents have been tried to attenuate the pressor response in laparoscopic cholecystectomy patients. We have compared single pre-induction intravenous injection of dexmedetomidine with labetalol for attenuation of haemodynamic stress response.

Methods: A total of 160 patients were considered for this prospective, randomized, double blind clinical study done in a single tertiary care institution. Read More

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December 2018

Variability of arterial and peripheral venous blood gases parameters in subjects with stable obstructive pulmonary disease

Rev Med Inst Mex Seguro Soc 2018 11 30;56(4):342-346. Epub 2018 Nov 30.

Instituto Mexicano del Seguro Social, Hospital de Cardiología, Departamento de Hipertensión Pulmonar y Corazón Derecho. Ciudad de México, México

Background: Peripheral venous blood gases may be useful in subjects with exacerbation of chronic obstructive pulmonary disease to evaluate their gas exchange.

Objective: To describe the variability of parameters of arterial and peripheral venous blood gases in subjects with stable obstructive pulmonary disease.

Methods: Cross-sectional design, consecutive subjects were studied in a blinded manner, while arterial and peripheral venous blood was obtained for analysis. Read More

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November 2018
1 Read

Association between renal dysfunction and metalloproteinase (MMP)-9 activity in hypertensive patients.

Nefrologia 2018 Nov 30. Epub 2018 Nov 30.

Laboratorio Traslacional Cardiorrenal, Instituto de Investigación i+12, Hospital Universitario 12 de Octubre, Madrid, España; Unidad de Hipertensión, Servicio de Nefrología, Hospital Universitario 12 de Octubre, Madrid, España. Electronic address:

Background And Objective: Matrix metalloproteinases (MMPs) are involved in deleterious tissue remodeling associated with target organ damage in renal disease. The aim of this study was to study the association between renal dysfunction and activity of the inflammatory metalloproteinase MMP-9 in hypertensive patients with mild-moderate chronic kidney disease (CKD).

Material And Methods: Plasmatic active MMP-9, total MMP-9, tissue inhibitor of MMP-9 (TIMP-1), MMP-9/TIMP-1 ratio and MMP-9-TIMP-1 interaction were analyzed in 37 hypertensive patients distributed by estimated glomerular filtration rate (eGFR) in 3 groups:>90, 90-60 y 60-30mL/min/1. Read More

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November 2018

Intracranial hypertension caused by superior sagittal sinus stenosis secondary to a depressed skull fracture: Case report and review of the literature.

Neurocirugia (Astur) 2018 Nov 15. Epub 2018 Nov 15.

Department of Neurosurgery, Complejo Hospitalario de Navarra, Pamplona (Navarra), Spain.

Depressed fractures that occur on the superior sagittal sinus (SSS) cause stenosis or thrombosis of the sinus in 11.5% of cases. Despite this, the appearance of signs and symptoms derived from high intracranial pressure is an infrequent event. Read More

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November 2018
1 Read

Predictors of postpartum diabetes mellitus in patients with gestational diabetes.

Endocrinol Diabetes Nutr 2018 Nov 15. Epub 2018 Nov 15.

Servicio de Endocrinología y Nutrición, Hospital Universitario Gregorio Marañón, Madrid, España.

Introduction: Gestational diabetes (GD) is related to development of diabetes mellitus (DM) after delivery. The predictive factors in this association are not yet well defined. Objetive: to study the predictive factors of dysglucosis in the postpartum period in a sample of patients with GD. Read More

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November 2018
5 Reads

Specific hypertension smartphone app to improve medication adherence in hypertension: a cluster-randomized trial.

Curr Med Res Opin 2018 Nov 15:1-15. Epub 2018 Nov 15.

f Unidad de Hipertension, Intern Medicine, San Carlos Hospital, Medicine University , UCM Madrid , Spain.

Intro: Digital interventions, such as smartphone applications (APP), are becoming an increasingly common way to support medication adherence and self-management in chronic illness.

Aim: To evaluate the effectiveness of the intervention in pharmacological therapeutic adherence of the mild-moderate arterial hypertension (AHT), through an APP installed in the mobile phone, as well as the degree of control reached by the patient with this tool.

Methods: Prospective, randomized controlled trial, full-study and multicenter study. Read More

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November 2018
4 Reads

Finerenone Attenuates Endothelial Dysfunction and Albuminuria in a Chronic Kidney Disease Model by a Reduction in Oxidative Stress.

Front Pharmacol 2018 9;9:1131. Epub 2018 Oct 9.

Instituto Pluridisciplinar and Facultad de Farmacia, Universidad Complutense de Madrid, Madrid, Spain.

Albuminuria is an early marker of renovascular damage associated to an increase in oxidative stress. The Munich Wistar Frömter (MWF) rat is a model of chronic kidney disease (CKD), which exhibits endothelial dysfunction associated to low nitric oxide availability. We hypothesize that the new highly selective, non-steroidal mineralocorticoid receptor (MR) antagonist, finerenone, reverses both endothelial dysfunction and microalbuminuria. Read More

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October 2018
2 Reads

Comparing Office, Central, Home and Ambulatory Blood Pressure in Predicting Left Ventricular Mass.

Hipertens Riesgo Vasc 2018 Oct 18. Epub 2018 Oct 18.

Hospital Italiano de Buenos Aires, Argentina.

The blood pressure measurement method that more accurately predicts a left ventricular mass is controversial, and the evidence suggesting superiority of central over brachial measurements is contradictory. The aim of this study was to compare the relationship between the different clinic and out-of-clinic blood pressure measurements methods with left ventricular mass in patients who attended a specialised hypertension centre for a central blood pressure measurement. An analysis was performed on the correlations between left ventricular mass and central and brachial blood pressure measurements made in the clinic, and home, as well as 24-h systolic blood pressure measurements. Read More

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October 2018

[Arterial Hypertension register in private clinics in Venezuela: RHAVEN Study].

Hipertens Riesgo Vasc 2018 Oct 17. Epub 2018 Oct 17.

Cardiología, Policlínica Metropolitana, Caracas, Distrito Capital, Venezuela.

Introduction: In Venezuela, no large studies have been conducted to determine the level of control of hypertension (HT).

Objective: The primary objective was to know the prevalence of controlled HT among hypertensive patients treated pharmacologically.

Materials And Methods: A cross-section study was conducted on patients 18years and older. Read More

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October 2018
5 Reads

Adherence to an Energy-restricted Mediterranean Diet Score and Prevalence of Cardiovascular Risk Factors in the PREDIMED-Plus: A Cross-sectional Study.

Rev Esp Cardiol (Engl Ed) 2018 Oct 1. Epub 2018 Oct 1.

Centro de Investigación Biomédica en Red de la Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III (ISCIII), Madrid, Spain; Departamento de Medicina Preventiva y Salud Pública, Universidad de Navarra, Instituto de Investigación Sanitaria de Navarra (IdiSNA), Pamplona, Spain.

Introduction And Objectives: The cardiovascular benefits of the Mediterranean diet have usually been assessed under assumptions of ad libitum total energy intake (ie, no energy restriction). In the recently launched PREDIMED-Plus, we conducted exploratory analyses to study the baseline associations between adherence to an energy-restricted Mediterranean diet (MedDiet) and the prevalence of cardiovascular risk factors (CVRF).

Methods: Cross-sectional assessment of all PREDIMED-Plus participants (6874 older adults with overweight/obesity and metabolic syndrome) at baseline. Read More

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October 2018
4 Reads

Blood pressure control and impact on cardiovascular events in patients with type 2 diabetes mellitus: A critical analysis of the literature.

Clin Investig Arterioscler 2018 Sep 28. Epub 2018 Sep 28.

Grupo de estudio de enfermedades metabólicas, Facultad Ciencias de la Salud, Departamento de Medicina Interna, Universidad del Cauca, Popayán, Cauca, Colombia.

High blood pressure in individuals with type2 diabetes mellitus increases the risk of cardiovascular events. The international management guidelines recommend starting pharmacological treatment with blood pressure values >140/90mmHg. However, there is no optimal cut-off point from which cardiovascular events can be reduced without causing adverse events. Read More

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September 2018
5 Reads

Phaco-non-penetrating deep sclerectomy in ocular hypertension secondary to dexamethasone intravitreal implant.

Arch Soc Esp Oftalmol 2018 Dec 25;93(12):580-585. Epub 2018 Sep 25.

Departamento de Oftalmología, Instituto Ramón y Cajal de Investigación Sanitaria, Hospital Ramón y Cajal, Madrid, España.

Purpose: To evaluate the characteristics and progression of patients treated with a 0.7mg dexamethasone intravitreal implant (Ozurdex) and required glaucoma filtering surgery (phaco-non-penetrating deep sclerectomy) to control ocular hypertension (OHT).

Methods: A retrospective observational study including patients treated with Ozurdex in a tertiary-care university hospital from May 2011 to April 2016. Read More

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December 2018
2 Reads

Lack of Correlation of Carotid Intima-Media Index and Peripheral Artery Disease.

High Blood Press Cardiovasc Prev 2018 Dec 24;25(4):379-383. Epub 2018 Sep 24.

Servicio de Cirugía Vascular, Unidad de Hipertensión Arterial, Hospital Infanta Cristina, Carretera de Portugal s/n., 06070, Badajoz, Spain.

Introduction: Increased carotid intima-media thickness (IMT) measurement is usually seen as a surrogate marker of peripheral artery disease (PAD) but there is scarce cumulated evidence to support this view.

Aim: To evaluate prevalence of increased IMT among patients with symptomatic PAD as well as the frequency of some cardiovascular risk factors in these patients.

Methods: They were recruited 230 patients with diagnosis of medium peripheral artery disease in the Vascular Surgery Service outpatient's office. Read More

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December 2018

[Hypertensive urgencies: Description of clinical characteristics, management, variables associated with re-entry and short-term prognosis].

Hipertens Riesgo Vasc 2018 Sep 20. Epub 2018 Sep 20.

Servicio de Medicina Interna, Hospital Clínico Universitario Lozano Blesa, Zaragoza, España; Unidad de Hipertensión, Hospital Clínico Universitario Lozano Blesa, Zaragoza, España.

Objectives: To describe the characteristics of hypertensive urgencies at the emergency department, as well as the variables associated with early re-admission (<7 days) and re-admission at one month (<30 days).

Methods: We conducted a descriptive, retrospective study of all patients who were admitted to the emergency department of a third level hospital during 2013. Subsequently, a case-control analysis was performed to analyze the group of patients with readmission. Read More

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September 2018
12 Reads

[Asociación de la composición corporal total con la fuerza del tronco, el dolor y la discapacidad en pacientes con espondiloartrosis lumbar].

Cir Cir 2018 ;86(5):388-391

Subdirección de Medicina de Rehabilitación. Instituto Nacional de Rehabilitación Luis Guillermo Ibarra Ibarra, Ciudad de México, México.

Introducción: Las alteraciones en la composición corporal total podrían influir sobre la fuerza, el dolor y la discapacidad en pacientes con espondiloartrosis lumbar.

Objetivo: Analizar la asociación de la composición corporal total con la fuerza muscular del tronco, el dolor y la discapacidad en pacientes con espondiloartrosis lumbar.

Método: Estudio piloto en mayores de 50 años con dolor crónico de espalda baja y espondiloartrosis lumbar. Read More

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January 2018
1 Read

J-shaped curve for cardiovascular mortality: systolic or diastolic blood pressure?

J Nephrol 2018 Sep 17. Epub 2018 Sep 17.

Clinica Medica, Università Milano-Bicocca, Milan, Italy.

Aggressive reduction of blood pressure (BP) may increase cardiovascular events (the J-curve phenomenon) in certain populations. There is a high number of available studies of antihypertensive treatment that provide strong evidence for J-shaped relationships between both diastolic and systolic BP and main cardiovascular outcomes. Nonetheless, most available studies were observational, and randomized trials might not have or lost their statistical power in post-hoc analysis. Read More

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September 2018

[Examining hypertension in children and adolescents: Clinical implications of the differences between the European and American Guidelines].

An Pediatr (Barc) 2018 Oct 13;89(4):255.e1-255.e5. Epub 2018 Sep 13.

Servicio de Pediatría, Consorcio Hospital General Universitario de Valencia, Valencia, España; CIBER Fisiopatología Obesidad y Nutrición (CB06/03), Instituto de Salud Carlos III, Madrid, España; INCLIVA, Instituto de Investigación, Valencia, España. Electronic address:

Over the past 2 years, new guidelines for hypertension in children and adults have been published. The first, developed by the European Hypertension Society Working Group on Hypertension in Children and Adolescents, recognised the need for an update of the of the 2009 European Guidelines of in order to incorporate the new information acquired over the last few years. Subsequently, an update of the American guidelines (the most recent of which was in 2004), has been published. Read More

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October 2018

Evaluation of the effect of relaxation therapy in patients with arterial hypertension.

Enferm Clin 2018 Aug 9. Epub 2018 Aug 9.

Departamento de Enfermería, Fisioterapia y Medicina, Universidad de Almería, Almería, España.

Objectives: To evaluate whether the application of a relaxation therapy reduces the blood pressure in hypertensive patients and whether there is improvement in several parameters which can influence blood pressure such as anxiety, quality of life and sleep.

Methods: A quasi-experimental study (measures before-after) was performed in 25 Primary Care patients with hypertension poorly controlled by pharmacological treatment. The intervention consisted of relaxation therapy composed of 3techniques: passive relaxation of Schwartz-Haynes, diaphragmatic breathing and imaginary visualization. Read More

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[Antecedentes maternos prenatales y riesgo de complicaciones neonatales en productos de término de bajo peso para edad gestacional].

Bol Med Hosp Infant Mex 2018 ;75(4):237-243

Hospital Español de México. Ciudad de México, México.

Introducción: El bajo peso neonatal (< 2.5 kg o < percentil 10) se atribuye a causas constitucionales (pequeño para la edad gestacional [PEG]) o a la restricción en el crecimiento intrauterino (RCIU), con riesgos posnatales diferentes. En ausencia de una valoración fetal-placentaria prenatal adecuada, resulta difícil establecerlo. Read More

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January 2018

[Diagnostic approach of pheochromocytomas and paragangliomas].

Hipertens Riesgo Vasc 2018 Aug 2. Epub 2018 Aug 2.

CEDIE, Hospital de Niños Ricardo Gutiérrez, Ciudad Autónoma de Buenos Aires, Argentina.

Pheochromocytomas and paragangliomas are rare neuroendocrine tumours associated with high morbidity and mortality. Recognizing the clinical presentation is the first step for diagnosis. Biochemical studies may determine an excess of catecholamines and their metabolites. Read More

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[Epidemiología y desenlaces de la lesión renal aguda en Latinoamérica].

Gac Med Mex 2018 ;154(Supp 1):S6-S14

Universidad de la República, Montevideo, Uruguay.

La lesión renal aguda (LRA) o injuria renal aguda, como se describe en Sudamérica, está sobreestimada por estudios epidemiológicos de países de alto nivel económico. En Latinoamérica (LA) existe un vacío de información sobre la epidemiología de la LRA. Se realizó una búsqueda de artículos publicados en LA referentes a la LRA y se hallaron 61 estudios, que representan a 10,670 pacientes latinoamericanos, en los cuales se distingue entre población adulta y pediátrica, LRA adquirida en la comunidad (LRA-AC) y adquirida en el hospital (LRA-AH), y se describen sus etiologías y desenlaces. Read More

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January 2018

Changes in the choroid plexuses and brain barriers associated with high blood pressure and ageing.

Neurologia 2018 Jul 27. Epub 2018 Jul 27.

Departamento de Anatomía, Facultad de Medicina, Universidad de La Laguna, La Laguna, Tenerife, España; Instituto de Investigación y Ciencias de Puerto de Rosario, Puerto del Rosario, Fuerteventura, España. Electronic address:

Introduction: The choroid plexuses, blood vessels, and brain barriers are closely related both in terms of morphology and function. Hypertension causes changes in cerebral blood flow and in small vessels and capillaries of the brain. This review studies the effects of high blood pressure (HBP) on the choroid plexuses and brain barriers. Read More

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Consensus document of the Spanish Society of Arteriosclerosis (SEA) for the prevention and treatment of cardiovascular disease in type 2 diabetes mellitus.

Clin Investig Arterioscler 2018 Jul;30 Suppl 1:1-19

Hospital Clínico-Universitat de València, INCLIVA Research Institute, CIBER de Diabetes y Enfermedades Metabólicas (CIBERDEM), ISCIII, Valencia, España.

A consensus document of the Diabetes working group of the Spanish Society of Arteriosclerosis (SEA) is presented, based on the latest studies and conceptual changes that have appeared. It presents the cardiovascular risk in type 2 diabetes mellitus (T2DM) and the action guidelines for the prevention and treatment of cardiovascular disease (CVD) associated with T2DM. The importance of lipid control, based on the objective of LDL-C and non-HDL-C when there is hypertriglyceridemia, and the blood pressure control in the prevention and treatment of CVD is evaluated. Read More

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July 2018
2 Reads

[Recommendations on the treatment of hypertension in the secondary prevention of ischemic stroke].

Hipertens Riesgo Vasc 2018 Oct - Dec;35(4):e11-e18. Epub 2018 Jul 2.

Área Atención Integrada Riesgo Vascular, Servicio de Medicina Interna, Hospital Moisés Broggi-Consorci Sanitari Integral, Universidad de Barcelona , Barcelona, España.

Stroke continues to be one of the leading causes of death and disability in the world. One of the main problems with a patient who has survived from a stroke is the possibility of developing a new vascular episode again. Hypertension is the modifiable vascular risk factor with the greatest impact for both primary prevention and stroke recurrence. Read More

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July 2018
1 Read

[Tools to improve efficiency in the clinical management of hypertensive patients].

Hipertens Riesgo Vasc 2018 Jul 20. Epub 2018 Jul 20.

Weber, Economía y Salud, Majadahonda, España. Electronic address:

Objective: To create a tool to evaluate the efficiency of the clinical management of hypertensive patients in Primary Care.

Material And Methods: A web-based questionnaire was designed for Primary Care centres to self-evaluate the management of hypertension in five specific areas: information systems, diagnostic and analytical tests, organisational aspects, use of resources, and continuous training programmes for patients and healthcare professionals. A committee of experts previously defined these questions and their ideal responses or "control", based on the scientific literature or, if there were no published references, by consensus of the committee. Read More

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July 2018
5 Reads

Impact of the application of the JNC 8 and KDIGO-2013 guidelines on hypertension and lipid control in a Nephrology outpatient clinic.

Nefrologia 2018 Jul - Aug;38(4):379-385

Hospital General Universitario Gregorio Marañón, Madrid, España.

Objective: Observational retrospective study with consecutive patients with CKD to assess the degree of accomplishment of the therapeutic objectives in hypertension and dyslipidaemia recommended by JNC 8 and KDIGO-2013 CKD guidelines the impact of their implementation compared with previous guidelines.

Results: 618 patients were included, mean age 67±15 years, 61.33% male. Read More

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November 2015
4 Reads

Impaired Mitophagy and Protein Acetylation Levels in Fibroblasts from Parkinson's Disease Patients.

Mol Neurobiol 2018 Jul 21. Epub 2018 Jul 21.

Departamento de Bioquímica y Biología Molecular y Genética. Facultad de Enfermería y Terapia Ocupacional, Universidad de Extremadura, Avda. de la Universidad s/n, 10003, Cáceres, Spain.

Parkinson's disease (PD) is a chronic and progressive neurodegenerative disorder. While most PD cases are idiopathic, the known genetic causes of PD are useful to understand common disease mechanisms. Recent data suggests that autophagy is regulated by protein acetylation mediated by histone acetyltransferase (HAT) and histone deacetylase (HDAC) activities. Read More

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July 2018
14 Reads

Physical activity levels are low in patients with pulmonary hypertension.

Ann Transl Med 2018 Jun;6(11):205

Pulmonary Hypertension Unit, Hospital Universitario 12 de Octubre, Madrid, Spain.

Background: Pulmonary hypertension (PH) leads to exercise capacity impairment, but limited data are available on the objective evaluation of physical activity (PA) levels in these patients.

Methods: We assessed PA levels using triaxial accelerometry in Spanish PH patients (n=75, 48±14 years, 65% female) and gender/age matched controls (n=107), and examined potential associations of meeting minimum international recommendations [moderate-vigorous PA (MVPA) ≥150 min/week] with survival predictors.

Results: With the exception of vigorous PA (with very low values in both groups), all accelerometry data showed significant differences between patients and controls, with lower PA levels and proportion of individuals meeting minimum PA guidelines, but higher inactivity time, in the former. Read More

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June 2018
1 Read

The value of ABPM and subclinical target organ damage parameters in diagnosis of resistant hypertension.

Nefrologia 2018 Jul 9. Epub 2018 Jul 9.

Departamento de Enfermería, Fisioterapia y Medicina, Universidad de Almería, Almería, España.

Introduction: We aimed to assess the effectiveness of ambulatory blood pressure monitoring (ABPM) and subclinical target organ damage parameters for diagnosis of resistant hypertension (RH).

Methods: We assessed demographic and anthropometric variables, the incidence of cardiovascular events and subclinical target organ damage (n=112). We also studied the relationship between these variables and the ABPM results. Read More

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July 2018
2 Reads

Depression and Anxiety in Patients With Pulmonary Hypertension: The Role of Life Satisfaction and Optimism.

Psychosomatics 2018 Apr 12. Epub 2018 Apr 12.

Department of Biological and Health Psychology, Autonomous University of Madrid, Madrid, Spain.

Background: Pulmonary hypertension is a highly disabling condition characterized by a progressive increase in pulmonary arterial pressure. Even though pulmonary hypertension may cause great emotional distress, research examining the determinants of patients' emotional well-being has been scarce and has mostly focused on the role of disease-related factors.

Objectives: This study examined whether patients' emotional well-being may be effected by their life circumstances. Read More

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April 2018
5 Reads

Chronic kidney disease in Spain: Prevalence and impact of accumulation of cardiovascular risk factors.

Nefrologia 2018 Nov - Dec;38(6):606-615. Epub 2018 Jun 18.

Departamento de Medicina Preventiva y Salud Pública, Facultad de Medicina, Universidad Autónoma de Madrid / IdiPAZ-CIBER in Epidemiology and Public Health (CIBERESP), Madrid, España. Electronic address:

Background: Chronic kidney disease (CKD) is a public health problem worldwide. We aimed to estimate the CKD prevalence in Spain and to examine the impact of the accumulation of cardiovascular risk factors (CVRF).

Material And Methods: We performed a nationwide, population-based survey evaluating 11,505 individuals representative of the Spanish adult population. Read More

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June 2018
11 Reads

[Mortality study from the Spanish Registry of ABPM. An appeal for the transition of ABPM to clinical practice].

Hipertens Riesgo Vasc 2018 Jun 13. Epub 2018 Jun 13.

Departamento de Medicina Preventiva y Salud Pública, Universidad Autónoma de Madrid/IdiPAZ y CIBER de Epidemiología y Salud Pública (CIBERESP), Madrid, España; Unidad de Hipertensión y Laboratorio de Hipertensión e Investigación Traslacional Cardiorrenal, Instituto de Investigación i+12, Hospital Universitario 12 de Octubre y CIBER de Enfermedad Cardiovascular (CIBERCV), Madrid, España; Escuela de Estudios Doctorales e Investigación, Universidad Europea de Madrid, Madrid, España.

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Posterior Reversible Leukoencephalopathy Syndrome: Case Series and Review of the Literature.

Reumatol Clin 2018 May 30. Epub 2018 May 30.

Servicio de Reumatología, Hospital Privado Universitario de Córdoba, Córdoba, Argentina.

Objective: To describe clinical manifestations, antecedents, comorbidities and associated treatments, imaging findings, and follow-up in patients with posterior reversible encephalopathy syndrome.

Methods: A retrospective, descriptive analysis of admitted patients was performed between June 2009 and May 2014 in a third-level care hospital. We evaluated age, sex, comorbidities, symptoms, values of blood pressure at admission, renal function, medication and time elapsed until the disappearance of symptoms. Read More

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May 2018
1 Read

Balloon Pulmonary Angioplasty for Inoperable Patients With Chronic Thromboembolic Pulmonary Hypertension. Observational Study in a Referral Unit.

Rev Esp Cardiol (Engl Ed) 2018 May 29. Epub 2018 May 29.

Servicio de Cardiología, Hospital Universitario 12 de Octubre, Universidad Complutense de Madrid, Madrid, Spain; Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBERCV), Madrid, Spain.

Introduction And Objectives: Balloon pulmonary angioplasty (BPA) for inoperable chronic thromboembolic pulmonary hypertension (CTEPH) is becoming widely accepted. Procedural refinement has reduced complications. Our primary objective was to analyze the results and complications of the first national BPA program. Read More

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May 2018
9 Reads

Mobile Health Solutions for Hypertensive Disorders in Pregnancy: Scoping Literature Review.

JMIR Mhealth Uhealth 2018 May 30;6(5):e130. Epub 2018 May 30.

Instituto de Biomedicina de Sevilla (IBiS), Laboratorio de Hipertensión Arterial e Hipercolesterolemia, Servicio Andaluz de Salud / Consejo Superior de Investigaciones Científicas / Universidad de Sevilla, Seville, Spain.

Background: Hypertensive disorders are the most common complications during pregnancy, occurring in 5% to 11% of pregnancies; gestational hypertension and preeclampsia are the leading causes of perinatal and maternal morbidity and mortality, especially in low- and middle-income countries (LMIC) where maternal and perinatal mortality ratios are still high. Pregnant women with hypertensive disorders could greatly benefit from mobile health (mHealth) solutions as a novel way to identify and control early symptoms, as shown in an increasing number of publications in the field. Such digital health solutions may overcome access limiting factors and the lack of skilled medical professionals and finances commonly presented in resource-poor environments. Read More

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May 2018
1 Read

Letter by Hernandez-Gonzalez et al Regarding Article, "Phenotypic Characterization of Mutation Carriers in a Large Cohort of Patients Diagnosed Clinically With Pulmonary Arterial Hypertension".

Circulation 2018 May;137(22):2411-2412

Centro de Referencia Nacional de Hipertensión Pulmonar Compleja, Hospital Universitario Doce de Octubre, Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares, Madrid, Spain (P.E.-S.).

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Rationale and Methodology of the SARAH Trial: Long-Term Cardiovascular Outcomes in Patients With Resistant Hypertension and Obstructive Sleep Apnea.

Arch Bronconeumol 2018 Oct 23;54(10):518-523. Epub 2018 May 23.

Hospital Universitari Arnau de Vilanova and Santa Maria, Group of Translational Research in Respiratory Medicine, IRBLleida, Lleida, Cataluña, Spain; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Madrid, Spain. Electronic address:

Introduction: Patients with resistant hypertension (RH) have a high risk of developing cardiovascular events; therefore, new therapeutic approaches to better control blood pressure may be useful in improving cardiovascular outcomes. The prevalence of obstructive sleep apnea (OSA) is very high among patients with RH. Continuous positive airway pressure (CPAP) has been shown to be an effective treatment for reducing blood pressure in patients with RH. Read More

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October 2018
3 Reads

[Prevalence of obesity and arterial hypertension and their relationship with age and gender in the city of Resistencia, Argentina, in the years 2008-2014].

Hipertens Riesgo Vasc 2018 May 17. Epub 2018 May 17.

Laboratorio, Hospital Dr. Julio C. Perrando, Ministerio de Salud Pública, Provincia del Chaco, Resistencia (Chaco), Argentina; Fundación Renal del Nordeste Argentino, Resistencia (Chaco), Argentina.

Introduction: Obesity (OB) is a global pandemic, which is associated with arterial hypertension (AH). The differences in this relationship according to gender and age remain unclear. The objectives of this study were to establish the prevalence of OB and AH in an adult population, and to determine the risk of AH associated with OB in relationship to gender and age. Read More

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Cardiovascular risk factors: Is the metabolic syndrome related to aging? Epidemiology in a Portuguese population.

Diabetes Metab Syndr 2018 Nov 31;12(6):885-891. Epub 2018 May 31.

Departamento de Anatomía, Facultad de Medicina, Universidad de Extremadura, Spain.

Aims: The primary objective of our study is to determine the prevalence of the metabolic syndrome in the population. The secondary objective is to determine the prevalence of cardiovascular risk factors, anthropometric alterations and the prevalence of target organ damage and their relationship with aging.

Material And Methods: The sample for the study was obtained by means of a consecutive population-based demonstration in 803 adults over 18 years of age belonging to the labor force of the company Grupo Delta SA. Read More

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November 2018

Diabetes mellitus and cardiovascular risk: Update of the recommendations of the Diabetes and Cardiovascular Disease working group of the Spanish Diabetes Society (SED, 2018).

Clin Investig Arterioscler 2018 May - Jun;30(3):137-153. Epub 2018 May 10.

Hospital Universitario San Cecilio, Granada, España.

This document is an update to the clinical practice recommendations for the management of cardiovascular risk factors in diabetes mellitus. The consensus is made by members of the Cardiovascular Risk Group of the Spanish Diabetes Society. We have proposed and updated interventions on lifestyle, pharmacological treatment indicated to achieve therapeutic objectives according to the levels of HbA1c, degree of obesity, hypertension, hyperlipidemia, heart failure, platelet antiagregation, renal insufficiency, and diabetes in the elderly, as well as new biomarkers of interest in the evaluation of cardiovascular risk in individuals with diabetes mellitus. Read More

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October 2018
2 Reads

[Small vessel cerebrovascular disease].

Hipertens Riesgo Vasc 2018 Oct - Dec;35(4):185-194. Epub 2018 May 9.

Servicio de Neurología, Parc Sanitari Sant Joan de Deu, Sant Boi de Llobregat, España.

Small vessel vascular disease is a spectrum of different conditions that includes lacunar infarction, alteration of deep white matter, or microbleeds. Hypertension is the main risk factor, although the atherothrombotic lesion may be present, particularly in large-sized lacunar infarctions along with other vascular risk factors. MRI findings are characteristic and the lesions authentic biomarkers that allow differentiating the value of risk factors and defining their prognostic value. Read More

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[Air pollution, cardiovascular risk and hypertension].

Hipertens Riesgo Vasc 2018 Oct - Dec;35(4):177-184. Epub 2018 Apr 24.

Plaça Catalunya Primary Care Health Centre. Grup HTA de la Societat Catalana de Medicina de Família, Barcelona, España.

Air pollution is a worrying factor and has an impact on public health. Multiple studies relate exposure to air pollutants with an increase in cardiovascular events, cardiovascular mortality and mortality for all causes. A relationship has also been demonstrated between increased pollution and high blood pressure, as well as a higher prevalence of hypertension. Read More

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[Spanish Society of Hypertension position statement on the 2017 ACC/AHA hypertension guidelines].

Hipertens Riesgo Vasc 2018 Apr 24. Epub 2018 Apr 24.

Instituto de Investigación i+12, Hospital Universitario 12 de Octubre, Madrid, España; Unidad de Hipertensión, Servicio de Nefrología, Hospital Universitario 12 de Octubre, Madrid, España.

The American College of Cardiology (ACC) and the American Heart Association (AHA) have recently published their guidelines for the prevention, detection, evaluation, and management of hypertension in adults. The most controversial issue is the classification threshold at 130/80mmHg, which will allow a large number of patients to be diagnosed as hypertensive who were previously considered normotensive. Blood pressure (BP) is considered normal (<120mmHg systolic and <80mmHg diastolic), elevated (120-129 and <80mmHg), stage 1 (130-139 or 80-89mmHg), and stage 2 (≥140 or ≥90mmHg). Read More

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April 2018
3 Reads

[Pulmonary arterial hypertension associated with human immunodeficiency virus: thirty years after its description].

Arch Cardiol Mex 2018 Apr 11. Epub 2018 Apr 11.

Jefatura de Áreas Críticas, Instituto Nacional de Enfermedades Respiratorias, Ciudad de México, México. Electronic address:

The development of pulmonary arterial hypertension associated with human immunodeficiency virus reduces the probability of survival in the patient affected compared to those without cardiopulmonary disease. The pathophysiology is uncertain. There are several lines of research to associate the different proteins of the virus in the endothelial lesion. Read More

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Interventional Therapies in Pulmonary Hypertension.

Authors:
Julio Sandoval

Rev Esp Cardiol (Engl Ed) 2018 Jul 13;71(7):565-574. Epub 2018 Mar 13.

Departamento de Investigación Clínica, Instituto Nacional de Cardiología Ignacio Chávez, Mexico City, Mexico. Electronic address:

Despite advances in drug therapy, pulmonary hypertension-particularly arterial hypertension (PAH)-remains a fatal disease. Untreatable right heart failure (RHF) from PAH eventually ensues and remains a significant cause of death in these patients. Lowering pulmonary input impedance with different PAH-specific drugs is the obvious therapeutic target in RHF due to chronically increased afterload. Read More

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July 2018
1 Read

Pulmonary arterial hypertension associated to systemic erythematosus lupus: molecular characterization of 3 cases.

Med Clin (Barc) 2018 Aug 8;151(3):111-115. Epub 2018 Mar 8.

Departamento de Bioquímica, Genética e Inmunología, Facultad de Biología, Universidad de Vigo, Vigo, España; Instituto de Investigación Biomédica de Ourense-Pontevedra-Vigo (IIS Galicia Sur), Pontevedra, España. Electronic address:

Background And Objective: Pulmonary arterial hypertension associated with systemic lupus erythematosus (PAH-SLE) is a rare disease with a low incidence rate. In this study, PAH related genes and genetic modifiers were characterised molecularly in patients with PAH-SLE.

Patients And Methods: Three patients diagnosed with PAH-SLE and 100 control individuals were analysed after signing an informed consent. Read More

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August 2018
3 Reads

Rate and factors influencing the conversion of abstracts presented at the argentinian congress of hypertension meetings to indexed full peer-reviewed publications.

Hipertens Riesgo Vasc 2018 Mar 1. Epub 2018 Mar 1.

Argentinian Society of Hypertension, Argentina.

Introduction: Publication rates vary significantly among different scientific meetings, with many abstracts never being published as peer-reviewed articles. This issue has never been investigated in the Hypertension field in Argentina. Our purpose was to determine the proportion of abstracts presented at the Argentinian Congress of Hypertension meetings that were published as full articles in peer-reviewed indexed journals, the time lag to publication and the factors associated with successful publication. Read More

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Multicomponent exercise decreases blood pressure, heart rate and double product in normotensive and hypertensive older patients with high blood pressure.

Arch Cardiol Mex 2018 Feb 26. Epub 2018 Feb 26.

Department of Adapted Physical Activity (DEAFA), School of Physical Education, University of Campinas, Av. Érico Veríssimo, 701. Cidade Universitária "Zeferino Vaz", Barão Geraldo, Campinas, SP, Brazil.

Objective: The present study aimed to investigate the effects of a 6-month multicomponent exercise program on blood pressure, heart rate, and double product of uncontrolled and controlled normotensive and hypertensive older patients.

Methods: The study included 183 subjects, 97 normotensives, of which 53 were controlled normotensives (CNS), and 44 uncontrolled normotensives (UNS), as well as 86 hypertensives, of which 43 were controlled hypertensives (CHS), and 43 uncontrolled hypertensives (UHS). Volunteers were recruited and blood pressure and heart rate measurements were made before and after a 6-month multicomponent exercise program. Read More

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February 2018
2 Reads