952 results match your criteria Hipertension y Riesgo Cardiovascular[Journal]


Pulmonary endarterectomy. Initial report in a cardiology hospital

Rev Med Inst Mex Seguro Soc 2019 Jan 28;56(5):478-485. Epub 2019 Jan 28.

Instituto Mexicano del Seguro Social, Hospital de Cardiología, Departamento de Hipertensión Pulmonar y Función Ventricular Derecha. Ciudad de México, México

Background: Currently the options for treatment of chronic thromboembolic pulmonary hypertension can be pulmonary endarterectomy, pulmonary angioplasty and pharmacological treatment.

Objective: To show the feasibility of performing pulmonary endarterectomy in a cardiology hospital.

Methods: From December 2013 to June 2014 a serie of consecutive cases was studied according to the guidelines of the Fifth World Symposium of Pulmonary Hypertension. Read More

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January 2019

Primary aldosteronism: Aldosterone/renin ratio cut-off points.

Endocrinol Diabetes Nutr 2019 Feb 5. Epub 2019 Feb 5.

Servicio de Endocrinología, Hospital José María Ramos Mejía, Ciudad de Buenos Aires, Argentina.

Introduction: Primary aldosteronism (PA) is the most common cause of endocrine hypertension, with a prevalence rate of 6-12% in hypertensive patients. Aldosterone/renin ratio (ARR) is the screening test of choice for PA. Because of the variable cut-off points of ARR, reference values related to the populations and methods considered are recommended. Read More

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http://dx.doi.org/10.1016/j.endinu.2018.11.008DOI Listing
February 2019

[Prevalence and clinical features of non-alcoholic steatohepatitis in a hypertensive population].

Hipertens Riesgo Vasc 2019 Jan 14. Epub 2019 Jan 14.

Teoría de la Señal y las Comunicaciones y Sistemas Telemáticos y Computación, Universidad Rey Juan Carlos, Móstoles, Madrid, España.

Objective: Non-alcoholic fatty liver is a chronic liver disease in which fat is deposited in the liver, causing an inflammation called non-alcoholic steatohepatitis (NASH), and fibrosis. NASH is associated with metabolic syndrome (MS) and other cardiovascular risk factors. The aim of this study was to analyse the epidemiological features of NASH within a hypertensive population, with a high prevalence of MS, and to determine the features related to NASH. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S18891837183009
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http://dx.doi.org/10.1016/j.hipert.2018.10.001DOI Listing
January 2019
6 Reads

Prevalencia de factores de riesgo cardiovascular en escolares de un área rural y de una urbana en Colombia.

Biomedica 2018 Dec 1;38(4):545-554. Epub 2018 Dec 1.

Fundación Cardioinfantil - Instituto de Cardiología, Bogotá, D.C., Colombia.

Introducción. Los factores de riesgo cardiovascular tienen su origen en la infancia. En diversos estudios, se han registrado diferencias en la prevalencia de tales factores entre las áreas rurales y las urbanas, probablemente asociadas con los estilos de vida. Read More

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http://dx.doi.org/10.7705/biomedica.v38i4.4223DOI Listing
December 2018
1 Read

Blood pressure measurement and left ventricular mass: The difficult search for the best fit.

Authors:
E Rodilla

Hipertens Riesgo Vasc 2019 Jan - Mar;36(1):1-4. Epub 2019 Jan 3.

Unidad de Hipertensión y Riesgo Vascular, Servicio de Medicina Interna, Hospital Universitario de Sagunto, Universidad Cardenal Herrera-CEU, CEU Universities, Puerto de Sagunto, Valencia, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.hipert.2018.12.002DOI Listing
January 2019

MASked-unconTrolled hypERtension management based on office BP or on ambulatory blood pressure measurement (MASTER) Study: a randomised controlled trial protocol.

BMJ Open 2018 Dec 19;8(12):e021038. Epub 2018 Dec 19.

Fu Wai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical Colleges, Beijing, China.

Introduction: Masked uncontrolled hypertension (MUCH) carries an increased risk of cardiovascular (CV) complications and can be identified through combined use of office (O) and ambulatory (A) blood pressure (BP) monitoring (M) in treated patients. However, it is still debated whether the information carried by ABPM should be considered for MUCH management. Aim of the MASked-unconTrolled hypERtension management based on OBP or on ambulatory blood pressure measurement (MASTER) Study is to assess the impact on outcome of MUCH management based on OBPM or ABPM. Read More

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http://dx.doi.org/10.1136/bmjopen-2017-021038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303603PMC
December 2018
12 Reads
2.063 Impact Factor

The importance of patient perspectives in pulmonary hypertension.

Eur Respir J 2019 Jan 24;53(1). Epub 2019 Jan 24.

Pulmonary Hypertension Association, Silver Spring, MD, USA.

The assessment of objective measurement of cardiopulmonary status has helped us achieve better clinical outcomes for patients and develop new therapies through to the point of market access; however, patient surveys indicate that more can be done to improve holistic care and patient engagement. In this multidisciplinary review, we examine how clinical teams can acknowledge and embrace the individual patient's perspective, and thus improve the care for individual patients suffering from pulmonary hypertension by cultivating the importance and relevance of health-related quality of life in direct clinical care. At the individual level, patients should be provided with access to accredited specialist centres which provide a multidisciplinary approach where there is a culture focused on narrative medicine, quality of life, shared decision making and timely access to palliative care, and where there is participation in education. Read More

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http://dx.doi.org/10.1183/13993003.01919-2018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351339PMC
January 2019
7.636 Impact Factor

Comparative evaluation of dexmedetomidine and labetalol for attenuating hemodynamic stress responses during laparoscopic cholecystectomy in borderline hypertensive patients.

Rev Esp Anestesiol Reanim 2018 Dec 10. Epub 2018 Dec 10.

Department of Obstetrics and Gynecology, Himalayan Institute of Medical Sciences, Dehradun, Uttarakhand, India.

Objective: Various pharmacological agents have been tried to attenuate the pressor response in laparoscopic cholecystectomy patients. We have compared single pre-induction intravenous injection of dexmedetomidine with labetalol for attenuation of haemodynamic stress response.

Methods: A total of 160 patients were considered for this prospective, randomized, double blind clinical study done in a single tertiary care institution. Read More

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http://dx.doi.org/10.1016/j.redar.2018.11.004DOI Listing
December 2018
2 Reads

[Impacto de los nuevos criterios para diagnóstico y tratamiento de la hipertensión arterial sistémica sugeridos por la American College of Cardiology/American Heart Association].

Gac Med Mex 2018 ;154(6):633-637

Instituto Mexicano del Seguro Social, Programa "A todo Corazón-Código Infarto", Ciudad de México, México.

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http://dx.doi.org/10.24875/GMM.18004690DOI Listing
January 2018

Variability of arterial and peripheral venous blood gases parameters in subjects with stable obstructive pulmonary disease

Rev Med Inst Mex Seguro Soc 2018 11 30;56(4):342-346. Epub 2018 Nov 30.

Instituto Mexicano del Seguro Social, Hospital de Cardiología, Departamento de Hipertensión Pulmonar y Corazón Derecho. Ciudad de México, México

Background: Peripheral venous blood gases may be useful in subjects with exacerbation of chronic obstructive pulmonary disease to evaluate their gas exchange.

Objective: To describe the variability of parameters of arterial and peripheral venous blood gases in subjects with stable obstructive pulmonary disease.

Methods: Cross-sectional design, consecutive subjects were studied in a blinded manner, while arterial and peripheral venous blood was obtained for analysis. Read More

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November 2018
2 Reads

Association between renal dysfunction and metalloproteinase (MMP)-9 activity in hypertensive patients.

Nefrologia 2018 Nov 30. Epub 2018 Nov 30.

Laboratorio Traslacional Cardiorrenal, Instituto de Investigación i+12, Hospital Universitario 12 de Octubre, Madrid, España; Unidad de Hipertensión, Servicio de Nefrología, Hospital Universitario 12 de Octubre, Madrid, España. Electronic address:

Background And Objective: Matrix metalloproteinases (MMPs) are involved in deleterious tissue remodeling associated with target organ damage in renal disease. The aim of this study was to study the association between renal dysfunction and activity of the inflammatory metalloproteinase MMP-9 in hypertensive patients with mild-moderate chronic kidney disease (CKD).

Material And Methods: Plasmatic active MMP-9, total MMP-9, tissue inhibitor of MMP-9 (TIMP-1), MMP-9/TIMP-1 ratio and MMP-9-TIMP-1 interaction were analyzed in 37 hypertensive patients distributed by estimated glomerular filtration rate (eGFR) in 3 groups:>90, 90-60 y 60-30mL/min/1. Read More

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http://dx.doi.org/10.1016/j.nefro.2018.08.009DOI Listing
November 2018
1 Read

Intracranial hypertension caused by superior sagittal sinus stenosis secondary to a depressed skull fracture: Case report and review of the literature.

Neurocirugia (Astur) 2018 Nov 15. Epub 2018 Nov 15.

Department of Neurosurgery, Complejo Hospitalario de Navarra, Pamplona (Navarra), Spain.

Depressed fractures that occur on the superior sagittal sinus (SSS) cause stenosis or thrombosis of the sinus in 11.5% of cases. Despite this, the appearance of signs and symptoms derived from high intracranial pressure is an infrequent event. Read More

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http://dx.doi.org/10.1016/j.neucir.2018.10.002DOI Listing
November 2018
1 Read

Predictors of postpartum diabetes mellitus in patients with gestational diabetes.

Endocrinol Diabetes Nutr 2019 Feb 15;66(2):83-89. Epub 2018 Nov 15.

Servicio de Endocrinología y Nutrición, Hospital Universitario Gregorio Marañón, Madrid, España.

Introduction: Gestational diabetes (GD) is related to development of diabetes mellitus (DM) after delivery. The predictive factors in this association are not yet well defined. Objetive: to study the predictive factors of dysglucosis in the postpartum period in a sample of patients with GD. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S25300164183023
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http://dx.doi.org/10.1016/j.endinu.2018.08.013DOI Listing
February 2019
13 Reads

Specific hypertension smartphone app to improve medication adherence in hypertension: a cluster-randomized trial.

Curr Med Res Opin 2018 Nov 15:1-15. Epub 2018 Nov 15.

f Unidad de Hipertension, Intern Medicine, San Carlos Hospital, Medicine University , UCM Madrid , Spain.

Intro: Digital interventions, such as smartphone applications (APP), are becoming an increasingly common way to support medication adherence and self-management in chronic illness.

Aim: To evaluate the effectiveness of the intervention in pharmacological therapeutic adherence of the mild-moderate arterial hypertension (AHT), through an APP installed in the mobile phone, as well as the degree of control reached by the patient with this tool.

Methods: Prospective, randomized controlled trial, full-study and multicenter study. Read More

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http://dx.doi.org/10.1080/03007995.2018.1549026DOI Listing
November 2018
13 Reads

Finerenone Attenuates Endothelial Dysfunction and Albuminuria in a Chronic Kidney Disease Model by a Reduction in Oxidative Stress.

Front Pharmacol 2018 9;9:1131. Epub 2018 Oct 9.

Instituto Pluridisciplinar and Facultad de Farmacia, Universidad Complutense de Madrid, Madrid, Spain.

Albuminuria is an early marker of renovascular damage associated to an increase in oxidative stress. The Munich Wistar Frömter (MWF) rat is a model of chronic kidney disease (CKD), which exhibits endothelial dysfunction associated to low nitric oxide availability. We hypothesize that the new highly selective, non-steroidal mineralocorticoid receptor (MR) antagonist, finerenone, reverses both endothelial dysfunction and microalbuminuria. Read More

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https://www.frontiersin.org/article/10.3389/fphar.2018.01131
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http://dx.doi.org/10.3389/fphar.2018.01131DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189469PMC
October 2018
4 Reads

Comparing Office, Central, Home and Ambulatory Blood Pressure in Predicting Left Ventricular Mass.

Hipertens Riesgo Vasc 2019 Jan - Mar;36(1):5-13. Epub 2018 Oct 19.

Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.

The blood pressure measurement method that more accurately predicts a left ventricular mass is controversial, and the evidence suggesting superiority of central over brachial measurements is contradictory. The aim of this study was to compare the relationship between the different clinic and out-of-clinic blood pressure measurements methods with left ventricular mass in patients who attended a specialised hypertension centre for a central blood pressure measurement. An analysis was performed on the correlations between left ventricular mass and central and brachial blood pressure measurements made in the clinic, and home, as well as 24-h systolic blood pressure measurements. Read More

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http://dx.doi.org/10.1016/j.hipert.2018.09.001DOI Listing
October 2018

[Arterial Hypertension register in private clinics in Venezuela: RHAVEN Study].

Hipertens Riesgo Vasc 2018 Oct 17. Epub 2018 Oct 17.

Cardiología, Policlínica Metropolitana, Caracas, Distrito Capital, Venezuela.

Introduction: In Venezuela, no large studies have been conducted to determine the level of control of hypertension (HT).

Objective: The primary objective was to know the prevalence of controlled HT among hypertensive patients treated pharmacologically.

Materials And Methods: A cross-section study was conducted on patients 18years and older. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S18891837183009
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http://dx.doi.org/10.1016/j.hipert.2018.08.001DOI Listing
October 2018
5 Reads

Adherence to an Energy-restricted Mediterranean Diet Score and Prevalence of Cardiovascular Risk Factors in the PREDIMED-Plus: A Cross-sectional Study.

Rev Esp Cardiol (Engl Ed) 2018 Oct 1. Epub 2018 Oct 1.

Centro de Investigación Biomédica en Red de la Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III (ISCIII), Madrid, Spain; Departamento de Medicina Preventiva y Salud Pública, Universidad de Navarra, Instituto de Investigación Sanitaria de Navarra (IdiSNA), Pamplona, Spain.

Introduction And Objectives: The cardiovascular benefits of the Mediterranean diet have usually been assessed under assumptions of ad libitum total energy intake (ie, no energy restriction). In the recently launched PREDIMED-Plus, we conducted exploratory analyses to study the baseline associations between adherence to an energy-restricted Mediterranean diet (MedDiet) and the prevalence of cardiovascular risk factors (CVRF).

Methods: Cross-sectional assessment of all PREDIMED-Plus participants (6874 older adults with overweight/obesity and metabolic syndrome) at baseline. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S18855857183036
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http://dx.doi.org/10.1016/j.rec.2018.08.010DOI Listing
October 2018
10 Reads

Sobrediagnóstico y sobretratamiento en el ámbito cardiovascular: factores de riesgo, no enfermedades.

Aten Primaria 2018 Nov 28;50 Suppl 2:20-29. Epub 2018 Sep 28.

Grupo de Trabajo de Medicina Basada en la Evidencia de la Sociedad Murciana de Medicina Familiar y Comunitaria. Grupo de Trabajo de MBE de la SMUMFyC.

Cardiovascular risk factors, specifically arterial hypertension, hyperlipidemia and diabetes, represent a very important part in relation to the emerging problem of overdiagnosis and overtreatment in primary health care. The reasons that support this threat are diverse. Given its high prevalence and the fact that the intervention on them is not going to be reflected directly in the state of health, it is added that the diagnostic criteria and indications for pharmacological treatment are not based on solid evidence. Read More

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http://dx.doi.org/10.1016/j.aprim.2018.08.005DOI Listing
November 2018

Blood pressure control and impact on cardiovascular events in patients with type 2 diabetes mellitus: A critical analysis of the literature.

Clin Investig Arterioscler 2019 Jan - Feb;31(1):31-47. Epub 2018 Sep 28.

Grupo de estudio de enfermedades metabólicas, Facultad Ciencias de la Salud, Departamento de Medicina Interna, Universidad del Cauca, Popayán, Cauca, Colombia.

High blood pressure in individuals with type2 diabetes mellitus increases the risk of cardiovascular events. The international management guidelines recommend starting pharmacological treatment with blood pressure values >140/90mmHg. However, there is no optimal cut-off point from which cardiovascular events can be reduced without causing adverse events. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S02149168183010
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http://dx.doi.org/10.1016/j.arteri.2018.07.001DOI Listing
September 2018
5 Reads

Phaco-non-penetrating deep sclerectomy in ocular hypertension secondary to dexamethasone intravitreal implant.

Arch Soc Esp Oftalmol 2018 Dec 25;93(12):580-585. Epub 2018 Sep 25.

Departamento de Oftalmología, Instituto Ramón y Cajal de Investigación Sanitaria, Hospital Ramón y Cajal, Madrid, España.

Purpose: To evaluate the characteristics and progression of patients treated with a 0.7mg dexamethasone intravitreal implant (Ozurdex) and required glaucoma filtering surgery (phaco-non-penetrating deep sclerectomy) to control ocular hypertension (OHT).

Methods: A retrospective observational study including patients treated with Ozurdex in a tertiary-care university hospital from May 2011 to April 2016. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03656691183022
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http://dx.doi.org/10.1016/j.oftal.2018.06.011DOI Listing
December 2018
2 Reads

Lack of Correlation of Carotid Intima-Media Index and Peripheral Artery Disease.

High Blood Press Cardiovasc Prev 2018 Dec 24;25(4):379-383. Epub 2018 Sep 24.

Servicio de Cirugía Vascular, Unidad de Hipertensión Arterial, Hospital Infanta Cristina, Carretera de Portugal s/n., 06070, Badajoz, Spain.

Introduction: Increased carotid intima-media thickness (IMT) measurement is usually seen as a surrogate marker of peripheral artery disease (PAD) but there is scarce cumulated evidence to support this view.

Aim: To evaluate prevalence of increased IMT among patients with symptomatic PAD as well as the frequency of some cardiovascular risk factors in these patients.

Methods: They were recruited 230 patients with diagnosis of medium peripheral artery disease in the Vascular Surgery Service outpatient's office. Read More

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http://dx.doi.org/10.1007/s40292-018-0282-zDOI Listing
December 2018
1 Read

[Hypertensive urgencies: Description of clinical characteristics, management, variables associated with re-entry and short-term prognosis].

Hipertens Riesgo Vasc 2018 Sep 20. Epub 2018 Sep 20.

Servicio de Medicina Interna, Hospital Clínico Universitario Lozano Blesa, Zaragoza, España; Unidad de Hipertensión, Hospital Clínico Universitario Lozano Blesa, Zaragoza, España.

Objectives: To describe the characteristics of hypertensive urgencies at the emergency department, as well as the variables associated with early re-admission (<7 days) and re-admission at one month (<30 days).

Methods: We conducted a descriptive, retrospective study of all patients who were admitted to the emergency department of a third level hospital during 2013. Subsequently, a case-control analysis was performed to analyze the group of patients with readmission. Read More

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http://dx.doi.org/10.1016/j.hipert.2018.07.003DOI Listing
September 2018
20 Reads

[Asociación de la composición corporal total con la fuerza del tronco, el dolor y la discapacidad en pacientes con espondiloartrosis lumbar].

Cir Cir 2018 ;86(5):388-391

Subdirección de Medicina de Rehabilitación. Instituto Nacional de Rehabilitación Luis Guillermo Ibarra Ibarra, Ciudad de México, México.

Introducción: Las alteraciones en la composición corporal total podrían influir sobre la fuerza, el dolor y la discapacidad en pacientes con espondiloartrosis lumbar.

Objetivo: Analizar la asociación de la composición corporal total con la fuerza muscular del tronco, el dolor y la discapacidad en pacientes con espondiloartrosis lumbar.

Método: Estudio piloto en mayores de 50 años con dolor crónico de espalda baja y espondiloartrosis lumbar. Read More

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http://dx.doi.org/10.24875/CIRU.18000006DOI Listing
January 2018
2 Reads

J-shaped curve for cardiovascular mortality: systolic or diastolic blood pressure?

J Nephrol 2018 Sep 17. Epub 2018 Sep 17.

Clinica Medica, Università Milano-Bicocca, Milan, Italy.

Aggressive reduction of blood pressure (BP) may increase cardiovascular events (the J-curve phenomenon) in certain populations. There is a high number of available studies of antihypertensive treatment that provide strong evidence for J-shaped relationships between both diastolic and systolic BP and main cardiovascular outcomes. Nonetheless, most available studies were observational, and randomized trials might not have or lost their statistical power in post-hoc analysis. Read More

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http://dx.doi.org/10.1007/s40620-018-0535-xDOI Listing
September 2018

[Examining hypertension in children and adolescents: Clinical implications of the differences between the European and American Guidelines].

An Pediatr (Barc) 2018 Oct 13;89(4):255.e1-255.e5. Epub 2018 Sep 13.

Servicio de Pediatría, Consorcio Hospital General Universitario de Valencia, Valencia, España; CIBER Fisiopatología Obesidad y Nutrición (CB06/03), Instituto de Salud Carlos III, Madrid, España; INCLIVA, Instituto de Investigación, Valencia, España. Electronic address:

Over the past 2 years, new guidelines for hypertension in children and adults have been published. The first, developed by the European Hypertension Society Working Group on Hypertension in Children and Adolescents, recognised the need for an update of the of the 2009 European Guidelines of in order to incorporate the new information acquired over the last few years. Subsequently, an update of the American guidelines (the most recent of which was in 2004), has been published. Read More

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http://dx.doi.org/10.1016/j.anpedi.2018.08.004DOI Listing
October 2018

Evaluation of the effect of relaxation therapy in patients with arterial hypertension.

Enferm Clin 2018 Aug 9. Epub 2018 Aug 9.

Departamento de Enfermería, Fisioterapia y Medicina, Universidad de Almería, Almería, España.

Objectives: To evaluate whether the application of a relaxation therapy reduces the blood pressure in hypertensive patients and whether there is improvement in several parameters which can influence blood pressure such as anxiety, quality of life and sleep.

Methods: A quasi-experimental study (measures before-after) was performed in 25 Primary Care patients with hypertension poorly controlled by pharmacological treatment. The intervention consisted of relaxation therapy composed of 3techniques: passive relaxation of Schwartz-Haynes, diaphragmatic breathing and imaginary visualization. Read More

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http://dx.doi.org/10.1016/j.enfcli.2018.07.005DOI Listing

[Antecedentes maternos prenatales y riesgo de complicaciones neonatales en productos de término de bajo peso para edad gestacional].

Bol Med Hosp Infant Mex 2018 ;75(4):237-243

Hospital Español de México. Ciudad de México, México.

Introducción: El bajo peso neonatal (< 2.5 kg o < percentil 10) se atribuye a causas constitucionales (pequeño para la edad gestacional [PEG]) o a la restricción en el crecimiento intrauterino (RCIU), con riesgos posnatales diferentes. En ausencia de una valoración fetal-placentaria prenatal adecuada, resulta difícil establecerlo. Read More

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http://dx.doi.org/10.24875/BMHIM.M18000032DOI Listing
January 2018

[Diagnostic approach of pheochromocytomas and paragangliomas].

Hipertens Riesgo Vasc 2019 Jan - Mar;36(1):34-43. Epub 2018 Aug 2.

CEDIE, Hospital de Niños Ricardo Gutiérrez, Ciudad Autónoma de Buenos Aires, Argentina.

Pheochromocytomas and paragangliomas are rare neuroendocrine tumours associated with high morbidity and mortality. Recognizing the clinical presentation is the first step for diagnosis. Biochemical studies may determine an excess of catecholamines and their metabolites. Read More

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http://dx.doi.org/10.1016/j.hipert.2018.06.003DOI Listing

[Epidemiología y desenlaces de la lesión renal aguda en Latinoamérica].

Gac Med Mex 2018 ;154(Supp 1):S6-S14

Universidad de la República, Montevideo, Uruguay.

La lesión renal aguda (LRA) o injuria renal aguda, como se describe en Sudamérica, está sobreestimada por estudios epidemiológicos de países de alto nivel económico. En Latinoamérica (LA) existe un vacío de información sobre la epidemiología de la LRA. Se realizó una búsqueda de artículos publicados en LA referentes a la LRA y se hallaron 61 estudios, que representan a 10,670 pacientes latinoamericanos, en los cuales se distingue entre población adulta y pediátrica, LRA adquirida en la comunidad (LRA-AC) y adquirida en el hospital (LRA-AH), y se describen sus etiologías y desenlaces. Read More

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http://dx.doi.org/10.24875/GMM.M18000067DOI Listing
January 2018

Changes in the choroid plexuses and brain barriers associated with high blood pressure and ageing.

Neurologia 2018 Jul 27. Epub 2018 Jul 27.

Departamento de Anatomía, Facultad de Medicina, Universidad de La Laguna, La Laguna, Tenerife, España; Instituto de Investigación y Ciencias de Puerto de Rosario, Puerto del Rosario, Fuerteventura, España. Electronic address:

Introduction: The choroid plexuses, blood vessels, and brain barriers are closely related both in terms of morphology and function. Hypertension causes changes in cerebral blood flow and in small vessels and capillaries of the brain. This review studies the effects of high blood pressure (HBP) on the choroid plexuses and brain barriers. Read More

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http://dx.doi.org/10.1016/j.nrl.2018.06.001DOI Listing

Consensus document of the Spanish Society of Arteriosclerosis (SEA) for the prevention and treatment of cardiovascular disease in type 2 diabetes mellitus.

Clin Investig Arterioscler 2018 Jul;30 Suppl 1:1-19

Hospital Clínico-Universitat de València, INCLIVA Research Institute, CIBER de Diabetes y Enfermedades Metabólicas (CIBERDEM), ISCIII, Valencia, España.

A consensus document of the Diabetes working group of the Spanish Society of Arteriosclerosis (SEA) is presented, based on the latest studies and conceptual changes that have appeared. It presents the cardiovascular risk in type 2 diabetes mellitus (T2DM) and the action guidelines for the prevention and treatment of cardiovascular disease (CVD) associated with T2DM. The importance of lipid control, based on the objective of LDL-C and non-HDL-C when there is hypertriglyceridemia, and the blood pressure control in the prevention and treatment of CVD is evaluated. Read More

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http://dx.doi.org/10.1016/j.arteri.2018.06.006DOI Listing
July 2018
2 Reads

[Recommendations on the treatment of hypertension in the secondary prevention of ischemic stroke].

Hipertens Riesgo Vasc 2018 Oct - Dec;35(4):e11-e18. Epub 2018 Jul 2.

Área Atención Integrada Riesgo Vascular, Servicio de Medicina Interna, Hospital Moisés Broggi-Consorci Sanitari Integral, Universidad de Barcelona , Barcelona, España.

Stroke continues to be one of the leading causes of death and disability in the world. One of the main problems with a patient who has survived from a stroke is the possibility of developing a new vascular episode again. Hypertension is the modifiable vascular risk factor with the greatest impact for both primary prevention and stroke recurrence. Read More

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http://dx.doi.org/10.1016/j.hipert.2018.05.003DOI Listing
July 2018
1 Read

[Tools to improve efficiency in the clinical management of hypertensive patients].

Hipertens Riesgo Vasc 2018 Jul 20. Epub 2018 Jul 20.

Weber, Economía y Salud, Majadahonda, España. Electronic address:

Objective: To create a tool to evaluate the efficiency of the clinical management of hypertensive patients in Primary Care.

Material And Methods: A web-based questionnaire was designed for Primary Care centres to self-evaluate the management of hypertension in five specific areas: information systems, diagnostic and analytical tests, organisational aspects, use of resources, and continuous training programmes for patients and healthcare professionals. A committee of experts previously defined these questions and their ideal responses or "control", based on the scientific literature or, if there were no published references, by consensus of the committee. Read More

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http://dx.doi.org/10.1016/j.hipert.2018.06.002DOI Listing
July 2018
5 Reads

Impact of the application of the JNC 8 and KDIGO-2013 guidelines on hypertension and lipid control in a Nephrology outpatient clinic.

Nefrologia 2018 Jul - Aug;38(4):379-385

Hospital General Universitario Gregorio Marañón, Madrid, España.

Objective: Observational retrospective study with consecutive patients with CKD to assess the degree of accomplishment of the therapeutic objectives in hypertension and dyslipidaemia recommended by JNC 8 and KDIGO-2013 CKD guidelines the impact of their implementation compared with previous guidelines.

Results: 618 patients were included, mean age 67±15 years, 61.33% male. Read More

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http://dx.doi.org/10.1016/j.nefro.2017.10.003DOI Listing
November 2015
5 Reads

Impaired Mitophagy and Protein Acetylation Levels in Fibroblasts from Parkinson's Disease Patients.

Mol Neurobiol 2018 Jul 21. Epub 2018 Jul 21.

Departamento de Bioquímica y Biología Molecular y Genética. Facultad de Enfermería y Terapia Ocupacional, Universidad de Extremadura, Avda. de la Universidad s/n, 10003, Cáceres, Spain.

Parkinson's disease (PD) is a chronic and progressive neurodegenerative disorder. While most PD cases are idiopathic, the known genetic causes of PD are useful to understand common disease mechanisms. Recent data suggests that autophagy is regulated by protein acetylation mediated by histone acetyltransferase (HAT) and histone deacetylase (HDAC) activities. Read More

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http://dx.doi.org/10.1007/s12035-018-1206-6DOI Listing
July 2018
16 Reads

Physical activity levels are low in patients with pulmonary hypertension.

Ann Transl Med 2018 Jun;6(11):205

Pulmonary Hypertension Unit, Hospital Universitario 12 de Octubre, Madrid, Spain.

Background: Pulmonary hypertension (PH) leads to exercise capacity impairment, but limited data are available on the objective evaluation of physical activity (PA) levels in these patients.

Methods: We assessed PA levels using triaxial accelerometry in Spanish PH patients (n=75, 48±14 years, 65% female) and gender/age matched controls (n=107), and examined potential associations of meeting minimum international recommendations [moderate-vigorous PA (MVPA) ≥150 min/week] with survival predictors.

Results: With the exception of vigorous PA (with very low values in both groups), all accelerometry data showed significant differences between patients and controls, with lower PA levels and proportion of individuals meeting minimum PA guidelines, but higher inactivity time, in the former. Read More

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http://dx.doi.org/10.21037/atm.2018.05.37DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035982PMC
June 2018
3 Reads

The value of ABPM and subclinical target organ damage parameters in diagnosis of resistant hypertension.

Nefrologia 2019 Jan - Feb;39(1):67-72. Epub 2018 Jul 9.

Departamento de Enfermería, Fisioterapia y Medicina, Universidad de Almería, Almería, España.

Introduction: We aimed to assess the effectiveness of ambulatory blood pressure monitoring (ABPM) and subclinical target organ damage parameters for diagnosis of resistant hypertension (RH).

Methods: We assessed demographic and anthropometric variables, the incidence of cardiovascular events and subclinical target organ damage (n=112). We also studied the relationship between these variables and the ABPM results. Read More

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http://dx.doi.org/10.1016/j.nefro.2018.03.007DOI Listing
July 2018
2 Reads

Depression and Anxiety in Patients With Pulmonary Hypertension: The Role of Life Satisfaction and Optimism.

Psychosomatics 2018 Nov 12;59(6):575-583. Epub 2018 Apr 12.

Department of Biological and Health Psychology, Autonomous University of Madrid, Madrid, Spain.

Background: Pulmonary hypertension is a highly disabling condition characterized by a progressive increase in pulmonary arterial pressure. Even though pulmonary hypertension may cause great emotional distress, research examining the determinants of patients' emotional well-being has been scarce and has mostly focused on the role of disease-related factors.

Objectives: This study examined whether patients' emotional well-being may be effected by their life circumstances. Read More

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http://dx.doi.org/10.1016/j.psym.2018.04.002DOI Listing
November 2018
5 Reads

Chronic kidney disease in Spain: Prevalence and impact of accumulation of cardiovascular risk factors.

Nefrologia 2018 Nov - Dec;38(6):606-615. Epub 2018 Jun 18.

Departamento de Medicina Preventiva y Salud Pública, Facultad de Medicina, Universidad Autónoma de Madrid / IdiPAZ-CIBER in Epidemiology and Public Health (CIBERESP), Madrid, España. Electronic address:

Background: Chronic kidney disease (CKD) is a public health problem worldwide. We aimed to estimate the CKD prevalence in Spain and to examine the impact of the accumulation of cardiovascular risk factors (CVRF).

Material And Methods: We performed a nationwide, population-based survey evaluating 11,505 individuals representative of the Spanish adult population. Read More

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http://dx.doi.org/10.1016/j.nefro.2018.04.004DOI Listing
June 2018
14 Reads

[Mortality study from the Spanish Registry of ABPM. An appeal for the transition of ABPM to clinical practice].

Hipertens Riesgo Vasc 2018 Jun 13. Epub 2018 Jun 13.

Departamento de Medicina Preventiva y Salud Pública, Universidad Autónoma de Madrid/IdiPAZ y CIBER de Epidemiología y Salud Pública (CIBERESP), Madrid, España; Unidad de Hipertensión y Laboratorio de Hipertensión e Investigación Traslacional Cardiorrenal, Instituto de Investigación i+12, Hospital Universitario 12 de Octubre y CIBER de Enfermedad Cardiovascular (CIBERCV), Madrid, España; Escuela de Estudios Doctorales e Investigación, Universidad Europea de Madrid, Madrid, España.

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http://dx.doi.org/10.1016/j.hipert.2018.05.002DOI Listing

Posterior Reversible Leukoencephalopathy Syndrome: Case Series and Review of the Literature.

Reumatol Clin 2018 May 30. Epub 2018 May 30.

Servicio de Reumatología, Hospital Privado Universitario de Córdoba, Córdoba, Argentina.

Objective: To describe clinical manifestations, antecedents, comorbidities and associated treatments, imaging findings, and follow-up in patients with posterior reversible encephalopathy syndrome.

Methods: A retrospective, descriptive analysis of admitted patients was performed between June 2009 and May 2014 in a third-level care hospital. We evaluated age, sex, comorbidities, symptoms, values of blood pressure at admission, renal function, medication and time elapsed until the disappearance of symptoms. Read More

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http://dx.doi.org/10.1016/j.reuma.2018.04.006DOI Listing
May 2018
3 Reads

Balloon Pulmonary Angioplasty for Inoperable Patients With Chronic Thromboembolic Pulmonary Hypertension. Observational Study in a Referral Unit.

Rev Esp Cardiol (Engl Ed) 2018 May 29. Epub 2018 May 29.

Servicio de Cardiología, Hospital Universitario 12 de Octubre, Universidad Complutense de Madrid, Madrid, Spain; Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBERCV), Madrid, Spain.

Introduction And Objectives: Balloon pulmonary angioplasty (BPA) for inoperable chronic thromboembolic pulmonary hypertension (CTEPH) is becoming widely accepted. Procedural refinement has reduced complications. Our primary objective was to analyze the results and complications of the first national BPA program. Read More

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http://dx.doi.org/10.1016/j.rec.2018.02.020DOI Listing
May 2018
16 Reads

Mobile Health Solutions for Hypertensive Disorders in Pregnancy: Scoping Literature Review.

JMIR Mhealth Uhealth 2018 May 30;6(5):e130. Epub 2018 May 30.

Instituto de Biomedicina de Sevilla (IBiS), Laboratorio de Hipertensión Arterial e Hipercolesterolemia, Servicio Andaluz de Salud / Consejo Superior de Investigaciones Científicas / Universidad de Sevilla, Seville, Spain.

Background: Hypertensive disorders are the most common complications during pregnancy, occurring in 5% to 11% of pregnancies; gestational hypertension and preeclampsia are the leading causes of perinatal and maternal morbidity and mortality, especially in low- and middle-income countries (LMIC) where maternal and perinatal mortality ratios are still high. Pregnant women with hypertensive disorders could greatly benefit from mobile health (mHealth) solutions as a novel way to identify and control early symptoms, as shown in an increasing number of publications in the field. Such digital health solutions may overcome access limiting factors and the lack of skilled medical professionals and finances commonly presented in resource-poor environments. Read More

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http://dx.doi.org/10.2196/mhealth.9671DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6000483PMC
May 2018
1 Read

Letter by Hernandez-Gonzalez et al Regarding Article, "Phenotypic Characterization of Mutation Carriers in a Large Cohort of Patients Diagnosed Clinically With Pulmonary Arterial Hypertension".

Circulation 2018 May;137(22):2411-2412

Centro de Referencia Nacional de Hipertensión Pulmonar Compleja, Hospital Universitario Doce de Octubre, Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares, Madrid, Spain (P.E.-S.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.118.033641DOI Listing
May 2018
1 Read

Rationale and Methodology of the SARAH Trial: Long-Term Cardiovascular Outcomes in Patients With Resistant Hypertension and Obstructive Sleep Apnea.

Arch Bronconeumol 2018 Oct 23;54(10):518-523. Epub 2018 May 23.

Hospital Universitari Arnau de Vilanova and Santa Maria, Group of Translational Research in Respiratory Medicine, IRBLleida, Lleida, Cataluña, Spain; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Madrid, Spain. Electronic address:

Introduction: Patients with resistant hypertension (RH) have a high risk of developing cardiovascular events; therefore, new therapeutic approaches to better control blood pressure may be useful in improving cardiovascular outcomes. The prevalence of obstructive sleep apnea (OSA) is very high among patients with RH. Continuous positive airway pressure (CPAP) has been shown to be an effective treatment for reducing blood pressure in patients with RH. Read More

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http://dx.doi.org/10.1016/j.arbres.2018.03.002DOI Listing
October 2018
4 Reads

[Prevalence of obesity and arterial hypertension and their relationship with age and gender in the city of Resistencia, Argentina, in the years 2008-2014].

Hipertens Riesgo Vasc 2019 Jan - Mar;36(1):14-20. Epub 2018 May 17.

Laboratorio, Hospital Dr. Julio C. Perrando, Ministerio de Salud Pública, Provincia del Chaco, Resistencia (Chaco), Argentina; Fundación Renal del Nordeste Argentino, Resistencia (Chaco), Argentina.

Introduction: Obesity (OB) is a global pandemic, which is associated with arterial hypertension (AH). The differences in this relationship according to gender and age remain unclear. The objectives of this study were to establish the prevalence of OB and AH in an adult population, and to determine the risk of AH associated with OB in relationship to gender and age. Read More

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http://dx.doi.org/10.1016/j.hipert.2018.04.003DOI Listing
May 2018
1 Read

Cardiovascular risk factors: Is the metabolic syndrome related to aging? Epidemiology in a Portuguese population.

Diabetes Metab Syndr 2018 Nov 31;12(6):885-891. Epub 2018 May 31.

Departamento de Anatomía, Facultad de Medicina, Universidad de Extremadura, Spain.

Aims: The primary objective of our study is to determine the prevalence of the metabolic syndrome in the population. The secondary objective is to determine the prevalence of cardiovascular risk factors, anthropometric alterations and the prevalence of target organ damage and their relationship with aging.

Material And Methods: The sample for the study was obtained by means of a consecutive population-based demonstration in 803 adults over 18 years of age belonging to the labor force of the company Grupo Delta SA. Read More

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http://dx.doi.org/10.1016/j.dsx.2018.05.010DOI Listing
November 2018

Diabetes mellitus and cardiovascular risk: Update of the recommendations of the Diabetes and Cardiovascular Disease working group of the Spanish Diabetes Society (SED, 2018).

Clin Investig Arterioscler 2018 May - Jun;30(3):137-153. Epub 2018 May 10.

Hospital Universitario San Cecilio, Granada, España.

This document is an update to the clinical practice recommendations for the management of cardiovascular risk factors in diabetes mellitus. The consensus is made by members of the Cardiovascular Risk Group of the Spanish Diabetes Society. We have proposed and updated interventions on lifestyle, pharmacological treatment indicated to achieve therapeutic objectives according to the levels of HbA1c, degree of obesity, hypertension, hyperlipidemia, heart failure, platelet antiagregation, renal insufficiency, and diabetes in the elderly, as well as new biomarkers of interest in the evaluation of cardiovascular risk in individuals with diabetes mellitus. Read More

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http://dx.doi.org/10.1016/j.arteri.2018.03.002DOI Listing
October 2018
4 Reads

[Small vessel cerebrovascular disease].

Hipertens Riesgo Vasc 2018 Oct - Dec;35(4):185-194. Epub 2018 May 9.

Servicio de Neurología, Parc Sanitari Sant Joan de Deu, Sant Boi de Llobregat, España.

Small vessel vascular disease is a spectrum of different conditions that includes lacunar infarction, alteration of deep white matter, or microbleeds. Hypertension is the main risk factor, although the atherothrombotic lesion may be present, particularly in large-sized lacunar infarctions along with other vascular risk factors. MRI findings are characteristic and the lesions authentic biomarkers that allow differentiating the value of risk factors and defining their prognostic value. Read More

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http://dx.doi.org/10.1016/j.hipert.2018.04.002DOI Listing