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    What is hidradenitis suppurativa?
    Can Fam Physician 2017 Feb;63(2):114-120
    Lecturer in the Division of Dermatology at the University of Toronto.
    Objective: To provide family physicians with an understanding of the epidemiology, clinical features, diagnosis, and management of hidradenitis suppurativa (HS).

    Sources Of Information: A PubMed literature search was performed using the MeSH term hidradenitis suppurativa.

    Main Message: Hidradenitis suppurativa is a chronic, recurrent, and debilitating skin condition. Read More

    Prodromal symptoms in hidradenitis suppurativa.
    Clin Exp Dermatol 2017 Feb 14. Epub 2017 Feb 14.
    Department of Dermatology, Zealand University Hospital, Health Sciences Faculty, University of Copenhagen, Roskilde, Denmark.
    Background: Hidradenitis suppurativa (HS) is a chronic, inflammatory skin disease, which presents as recurrent nodules and sinus tracts (tunnels) with subsequent scarring, predominantly involving the intertriginous regions. Although prodromal symptoms (i.e. Read More

    Familial Mediterranean fever patients with hidradenitis suppurativa.
    Int J Dermatol 2017 Feb 14. Epub 2017 Feb 14.
    Department of Dermatology and Allergology, Ludwig-Maximilians University, Munich, Germany.
    Background: Hidradenitis suppurativa (HS) has recently been described as a component of two autoinflammatory syndromes: PASH (pyoderma gangrenosum, acne, and HS) and PAPASH (pyoderma gangrenosum, acne, pyogenic arthritis, and HS). These associations together with others such as inflammatory bowel diseases suggest that defects in autoinflammatory pathways may play a role in the pathogenesis of HS.

    Objectives: To describe clinical and genetic characteristics of two unrelated patients with HS and familial Mediterranean fever (FMF). Read More

    Hidradenitis suppurativa, neutrophilic dermatoses and diverticular disease in a young African-American patient.
    BMJ Case Rep 2017 Feb 10;2017. Epub 2017 Feb 10.
    Department of Dermatology, St Louis University, St Louis, Missouri, USA.
    Hidradenitis suppurativa (HS) is a chronic skin disorder of the terminal follicular epithelium of apocrine sweat glands, manifesting as painful and exudative papules, pustules, cysts or nodules. This inflammatory condition often presents with other systemic and cutaneous disorders. We present the case of an African-American man with HS who was also diagnosed with neutrophilic dermatoses and diverticular disease. Read More

    'At last we are delivering a gold standard service'.
    Nurs Stand 2017 Feb;31(24):24-26
    Dermatology consultant nurse Karina Jackson leads a team of nurses treating patients with severe psoriasis, severe eczema and hidradenitis suppurativa, a chronic skin condition that causes abscesses and scarring. Although the physical symptoms of these conditions can be distressing, it is their psychological impact that Ms Jackson describes as heartbreaking. Read More

    Adalimumab for Treating Moderate-to-Severe Hidradenitis Suppurativa: An Evidence Review Group Perspective of a NICE Single Technology Appraisal.
    Pharmacoeconomics 2017 Feb 7. Epub 2017 Feb 7.
    Nottingham NHS Treatment Centre, Nottingham, UK.
    As part of its single technology appraisal (STA) process, the UK National Institute for Health and Care Excellence (NICE) invited the manufacturer of adalimumab (AbbVie) to submit evidence on the clinical effectiveness and cost effectiveness of adalimumab for the treatment of moderate-to-severe hidradenitis suppurativa (HS). The appraisal assessed adalimumab as monotherapy in adult patients with an inadequate response to conventional systemic HS therapy. The School of Health and Related Research Technology Appraisal Group was commissioned to act as the independent Evidence Review Group (ERG). Read More

    Framingham risk assessment in Hidradenitis Suppurativa.
    Br J Dermatol 2017 Feb 6. Epub 2017 Feb 6.
    Department of Dermatology and the Dermatology Research Group, Education and Research Centre, St. Vincent's University Hospital, Elm Park, Dublin 4, Ireland.
    Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease with a known association with obesity [1]. Evidence of an association between metabolic syndrome and HS has been reported [2]. The Framingham Risk Score (FRS) [3] is a gender-specific algorithm used to estimate an individual's 10-year cardiovascular risk. Read More

    Boils at Frictional Locations in a Patient with Hidradenitis Suppurativa.
    Acta Dermatovenerol Croat 2016 Dec;24(4):303-304
    Jurr Boer, MD, PhD, Department of Dermatology Deventer Hospital, Nico Bolkesteinlaan 75, 7416 SE Deventer, The Netherlands;
    Dear Editor, Hidradenitis suppurativa (HS) is a chronic, recurrent, inflammatory skin disease. The primary clinical presentation are painful inflamed nodules or boils of inverse areas, i.e. Read More

    The Role of Androgens and Estrogens in Hidradenitis Suppurativa - A Systematic Review.
    Acta Dermatovenerol Croat 2016 Dec;24(4):239-249
    Peter Theut Riis, MD, Department of Dermatology University Hospital Zealand, Køgevej 7-13, 4000 Roskilde, Denmark;
    Hidradenitis suppurativa (HS) is an inflammatory skin disease. Several observations imply that sex hormones may play a role in its pathogenesis. HS is more common in women, and the disease severity appears to vary in intensity according to the menstrual cycle. Read More

    Surgery combined with photodynamic therapy for the treatment of Hidradenitis Suppurativa: a report of 7 cases.
    Photodiagnosis Photodyn Ther 2017 Jan 21. Epub 2017 Jan 21.
    Jiangsu Key Laboratory of Molecular Biology for Skin Diseases and STIs, Institute of Dermatology, Chinese Academy of Medical Science & Peking Union Medical College, Nanjing, China. Electronic address:
    Hidradenitis Suppurativa (HS) is a chronic inflammatory skin disease in the area of the apocrine sweat glands. The treatment of HS is relatively difficult. Therefore, surgery combined with PDT was applied to treat 7 cases of patients in this study, and treatment efficacy was observed. Read More

    Improvement of overlapping hidradenitis suppurativa and ankylosing spondylitis after the introduction of adalimumab.
    Reumatologia 2016 30;54(6):321-325. Epub 2016 Dec 30.
    Division of Clinical Immunology and Rheumatology, Department of Internal Medicine, University of Zagreb, School of Medicine, University Hospital Center Zagreb, Zagreb, Croatia.
    Hidradenitis suppurativa is a chronic inflammatory disorder characterized by occlusion of the follicular pilosebaceous units of the skin. The treatment options are sometimes very limited and unpleasant odor and abundant drainage complicate the disease. Ankylosing spondylitis is a form of seronegative spondyloarthritis with predominantly axial but also peripheral joint involvement. Read More

    Negative pressure wound therapy, staged excision and definitive closure with split-thickness skin graft for axillary hidradenitis suppurativa: a retrospective study.
    J Wound Care 2017 Jan;26(Sup1):S36-S42
    Louisiana State University Health Sciences Center (LSUHSC) Department of General/Burn Surgery.
    Objective: Bilateral axillary hidradenitis is a chronic, suppurative, and scarring disease that is most effectively treated by complete excision of all hair-bearing tissues. We assessed our staged procedure for excision and placement of a split-thickness skin graft for bilateral axillary hidradenitis in terms of costs, outcomes, and timing of excision.

    Method: An IRB approved retrospective case analysis was performed on patients that underwent bilateral axillary hidradenitis skin excision with eventual placement of split-thickness skin grafting using the current LSUHSC/University Health hidradenitis surgical treatment protocol. Read More

    Successful surgical treatment for squamous cell carcinoma arising from hidradenitis suppurativa: A case report and literature review.
    Medicine (Baltimore) 2017 Jan;96(3):e5857
    aDivision of Plastic and Reconstructive Surgery, Peking Union Medical College Hospital, Beijing, P.R. China bDepartment of Medicine, the University of Melbourne, Parkville, Victoria, Australia cDepartment of Pathology, Peking Union Medical College Hospital, Beijing, P.R. China.
    Rationale: Hidradenitis suppurativa (HS) is a disabling inflammatory disease mainly affecting apocrine glands. Marjolin ulcer (MU) is a term used to describe a rare type of squamous cell carcinoma (SCC) arising within sites of chronic wounds or preexisting scars. Chronic HS may result in a rare type of SCC, MU, which has a poor prognosis due to its high metastatic rate. Read More

    Disorders characterized by predominant or exclusive dermal inflammation.
    Semin Diagn Pathol 2016 Dec 14. Epub 2016 Dec 14.
    Section of Dermatopathology, Division of Surgical Pathology & Cytopathology, University of Virginia Medical Center, Room 3020 University of Virginia Hospital, 1215 Lee Street, Charlottesville, VA 22908-0214, USA. Electronic address:
    Some cutaneous inflammatory disorders are typified by a predominant or exclusive localization in the dermis. They can be further subdivided by the principal cell types into lymphocytic, neutrophilic, and eosinophilic infiltrates, and mixtures of them are also seen in a proportion of cases. This review considers such conditions. Read More

    Prevalence and risk of inflammatory bowel disease in patients with hidradenitis suppurativa.
    J Invest Dermatol 2017 Jan 12. Epub 2017 Jan 12.
    Eli Lilly and Company, Indianapolis, Indiana, United States.
    Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease. In small studies, inflammatory bowel disease (IBD) has been associated with increased prevalence of HS, but data on the concurrence of IBD in patients with HS is limited. We therefore investigated the prevalence and risk of IBD in patients with HS compared with the general population. Read More

    Epidemiology of hidradenitis suppurativa and inflammatory bowel disease: are these two disease associated?
    Actas Dermosifiliogr 2016 Sep;107 Suppl 2:8-12
    Servicio de Gastroenterología, Hospital General Universitario Gregorio Marañón, Madrid, España.
    Hidradenitis suppurativa and inflammatory bowel disease are chronic inflammatory diseases mainly affecting young people. Their aetiology is complex and multifactorial and numerous case series have shown that the two diseases can manifest concurrently, although the strength of this association varies widely among distinct reports. An additional problem is the difficulty of distinguishing between cutaneous Crohn disease and hidradenitis. Read More

    Epidemiological, clinical and therapeutic aspects in special situations: hidradenitis suppurativa in paediatric patients.
    Actas Dermosifiliogr 2016 Sep;107 Suppl 2:51-60
    Sección de Dermatología Pediátrica, Hospital Universitario La Paz, Madrid, España. Electronic address:
    Hidradenitis suppurativa usually develops in the third decade of life and is infrequent in children and adolescents. This article reviews the scant epidemiological clinical and therapeutic data that are available for this age group. From the epidemiological point of view, reports have been more numerous in children, which has been related to hormone alterations and with a possibly higher genetic load than when this disease develops in adults. Read More

    Clinical experience of the use of adalimumab in the management of hidradenitis suppurativa. Comparison of response rates with Crohn disease.
    Actas Dermosifiliogr 2016 Sep;107 Suppl 2:43-50
    Servicio de Dermatología, Hospital de Manises, Valencia, España. Electronic address:
    The recent approval of adalimumab as the first treatment to be approved for the management of hidradenitis suppurativa has represented a before and after in the control of this chronic inflammatory disease. Given the inflammatory burden of this cutaneous disease, in the last few years hidradenitis suppurativa has been compared with inflammatory bowel disease, particularly with Crohn disease, to the point of considering hidradenitis suppurativa as "Crohn disease of the skin". These two chronic inflammatory diseases show sufficient similarities to consider whether treatment response based on the inflammatory load could also be similar. Read More

    Management of patients with hidradenitis suppurativa.
    Actas Dermosifiliogr 2016 Sep;107 Suppl 2:32-42
    Servicio de Gastroenterología, Hospital General Universitario Gregorio Marañón, Madrid, España.
    Hidradenitis suppurativa (HS) is a chronic inflammatory disease with a high prevalence in the population. Treatment options are both medical and surgical. Medical treatment is based on the use of antibiotics, retinoids, and anti-inflammatory drugs, in which anti-TNFα agents (infliximab y adalimumab) play a central role in the treatment of moderate-to-severe HS and enjoy the highest level of scientific support. Read More

    Hidradenitis suppurativa and perianal Crohn disease: differential diagnosis.
    Actas Dermosifiliogr 2016 Sep;107 Suppl 2:27-31
    Unidad de Enfermedad Inflamatoria Intestinal, Servicio de Gastroenterología y Hepatología, Hospital Universitario Puerta de Hierro, Majadahonda, Madrid, España.
    The first description of perianal fistulas and complications in Crohn disease was made 75 years ago by Penner and Crohn. Published studies have subsequently confirmed that perianal fistulas are the most common manifestations of fistulising Crohn disease. Hidradenitis suppurativa was described in 1854 by a French surgeon, Aristide Verneuil. Read More

    Clinical features of hidradenitis suppurativa and Crohn disease: what do these two entities have in common?
    Actas Dermosifiliogr 2016 Sep;107 Suppl 2:21-26
    Unidad de Enfermedad Inflamatoria Intestinal, Servicio de Gastroenterología y Hepatología, Hospital Universitario Puerta de Hierro, Majadahonda, Madrid, España. Electronic address:
    Hidradenitis suppurativa (HS) and Crohn disease (CD) are chronic, recurrent inflammatory diseases. They share certain clinical characteristics and flares are common in both. Both entities are usually diagnosed between the second and third decades of life and share risk factors such as smoking and overweight. Read More

    Therapeutic approach to Crohn disease: possible parallels with hidradenitis suppurativa.
    Actas Dermosifiliogr 2016 Sep;107 Suppl 2:2-7
    Unidad EII, Servicio de Aparato Digestivo, Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM), Hospital General Universitario Gregorio Marañón, Madrid, España. Electronic address:
    The current controversy in the setting of dermatology surrounding the treatment of inflammatory diseases, and specifically hidradenitis suppurativa, bears strong similarities with the debate concerning inflammatory bowel disease (IBD) that took place several years ago. That debate led to new perspectives on this disease and, in particular, its treatment after the development of biological agents. Read More

    Pathogenesis: common pathways between hidradenitis suppurativa and Crohn disease.
    Actas Dermosifiliogr 2016 Sep;107 Suppl 2:13-20
    Servicio de Aparato Digestivo, Hospital General Universitario Gregorio Marañón-IiSGM, Madrid, España; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Barcelona, España; Departamento de Medicina, Facultad de Medicina, Universidad Complutense de Madrid, Madrid, España.
    Both hidradenitis suppurativa and Crohn disease are considered chronic inflammatory diseases due to immune dysregulation. The high prevalence of Crohn disease patients diagnosed with hidradenitis suppurativa suggests the existence of common pathogenic links. The present literature review analyses the similarities and differences in the pathogenesis of the two diseases, in the search for new research and knowledge targets. Read More

    Factors Contributing to Depression and Chronic Pain in Patients with Hidradenitis Suppurativa: Results from a Single-Center Retrospective Review.
    Dermatology 2017 Jan 10. Epub 2017 Jan 10.
    Center for Clinical Studies, Webster, TX, USA.
    Background: Hidradenitis suppurativa (HS) is a debilitating chronic disease that leads to inflammation and abscess formation in the involved skin, along with a malodorous discharge. Pain is a considerable aspect of HS and significantly impacts quality of life. In addition, HS is significantly associated with depression. Read More

    Epidermal psoriasiform hyperplasia, an unrecognized sign of folliculitis decalvans: A histological study of 26 patients.
    J Cutan Pathol 2017 Jan 9. Epub 2017 Jan 9.
    Hôpital Saint-Louis, Centre Sabouraud, Paris, France.
    Background: Follicular hyperkeratosis along with hyperplasia of the follicular and interfollicular epithelia are major histopathological characteristics of hidradenitis suppurativa (HS). The presence of an occasional thickening of lesional skin in some folliculitis decalvans (FD) patients and histological similarities between FD and HS led us to look for epidermal hyperplasia and follicular hyperkeratosis in FD patients.

    Patients And Method: We performed a retrospective histological analysis of 26 patients with FD. Read More

    Population Pharmacokinetics and Immunogenicity of Adalimumab in Adult Patients with Moderate-to-Severe Hidradenitis Suppurativa.
    Clin Pharmacokinet 2017 Jan 9. Epub 2017 Jan 9.
    AbbVie Inc., Clinical Pharmacology and Pharmacometrics, Department R4PK, Building AP31-3, 1 North Waukegan Road, North Chicago, IL, 60064, USA.
    Introduction: Hidradenitis suppurativa (HS) is a serious, debilitating, chronic inflammatory skin disease. Adalimumab is a fully human, immunoglobulin G1 monoclonal antibody specific for tumor necrosis factor-alpha recently approved for use in patients with HS. The aim of this study is to describe the population pharmacokinetics and immunogenicity of adalimumab in adult patients with HS. Read More

    Evaluating the Use of Hematological Parameters in Staging Hidradenitis Suppurativa.
    Wounds 2016 Dec 29. Epub 2016 Dec 29.
    Eskişehir Osmangazi University, Medical School, Eskişehir, Turkey.
    Introduction: Recently, it has been shown that hematological parameters may be used as markers of inflammatory response. In this study, the authors aimed to identify the potential roles of the neutrophil-lymphocyte ratio (NLR) and other hematological markers in the evaluation of hidradenitis suppurativa (HS), a chronic, recurrent inflammatory disease.

    Materials And Methods: A total of 35 patients, diagnosed with HS between January 1, 2012 and December 31, 2014, were categorized into 3 groups according to the Hurley staging system. Read More

    Hidradenitis suppurativa treated with tetracycline in combination with colchicine: a prospective series of 20 patients.
    Int J Dermatol 2017 Mar 4;56(3):346-350. Epub 2017 Jan 4.
    Department of Dermatology and Venereology, Andreas Sygros Skin Hospital, Athens, Greece.
    Background: Hidradenitis suppurativa (HS) is a chronic inflammatory skin disorder of the follicular epithelium.

    Objectives: The objective of the present study was to evaluate the effectiveness of the combination of tetracycline with colchicine in the treatment of HS.

    Methods: Twenty patients (10 women and 10 men) with HS were included in an open, prospective, pilot study. Read More

    Quality of Life and Psychosocial Implications in Patients with Hidradenitis Suppurativa.
    Dermatology 2017 Jan 5. Epub 2017 Jan 5.
    Department of Dermatology and Venereology, Andreas Sygros Hospital, Athens, Greece.
    Background: Hidradenitis suppurativa (HS) is a long-term skin disorder associated with high levels of psychological distress and significant life impact.

    Objective: To evaluate the quality of life, depression, anxiety, loneliness, and self-esteem in patients with HS.

    Methods: Ninety-four patients with HS were enrolled in the study. Read More

    Increased interleukin (IL)-17 serum levels in patients with hidradenitis suppurativa: Implications for treatment with anti-IL-17 agents.
    J Am Acad Dermatol 2016 Dec 29. Epub 2016 Dec 29.
    Department of Dermatology, Venereology, and Allergology, Wroclaw Medical University, Wrocław, Poland.
    Background: Biologics seem to offer a promising nonsurgical approach in hidradenitis suppurativa (HS), especially in disease with highly pronounced inflammation. Recent studies revealed increased expression of a broad range of cytokines in lesional HS skin, including interleukin (IL)-17.

    Objective: This study was undertaken to determine IL-17 serum levels in this group of patients. Read More

    Management of hidradenitis suppurativa in pregnancy.
    J Am Acad Dermatol 2016 Dec 29. Epub 2016 Dec 29.
    Department of Dermatology, Johns Hopkins University, Baltimore, Maryland. Electronic address:
    Hidradenitis suppurativa is a debilitating inflammatory skin disease with a chronic course and often disappointing response to treatment. Though a minority of persons (20%) reports symptom remission during pregnancy, the vast majority experiences no relief (72%), and few experience clinical deterioration (8%). Disease flares are also observed post-partum. Read More

    Treatment of hidradenitis suppurativa with intralesional photodynamic therapy with 5-aminolevulinic acid and 630nm laser beam.
    J Dermatol Sci 2017 Mar 19;85(3):241-246. Epub 2016 Dec 19.
    Department of Dermatology, Complejo Asistencial Universitario de León, Spain.
    Background: Hidradenitis suppurativa (HS) is a chronic relapsing inflammatory skin disease with multiple treatment options that have been used with mixed results.

    Objectives: To evaluate the effectiveness, safety and tolerability of intralesional photodynamic therapy (I-PDT) in the management of HS. Also, to assess the effect of this technique on the different areas treated. Read More

    The Burden of Common Skin Diseases Assessed with the EQ5D: a European Multi-centre Study in 13 Countries.
    Br J Dermatol 2016 Dec 29. Epub 2016 Dec 29.
    Department of Dermatology, Oslo University Hospital and Institute of Clinical Medicine University of Oslo, Norway.
    Background: Generic instruments measuring health related quality of life (HRQoL), like EQ5D, enable comparison of skin diseases with healthy populations and non-dermatological medical conditions, as well as calculation of utility data.

    Objectives: The aims were to measure HRQoL in patients with common skin diseases and healthy controls across Europe using the EQ5D.

    Methods: This multi-center observational cross-sectional study was conducted in 13 European countries. Read More

    Expression of miRNA-155, miRNA-223, miRNA-31, miRNA-21, miRNA-125b, and miRNA-146a in the Inflammatory Pathway of Hidradenitis Suppurativa.
    Inflammation 2016 Dec 28. Epub 2016 Dec 28.
    Dermatologic Surgery Department, Department of Dermatology, Venereology and Allergology, Ruhr-University Bochum, Gudrunstr. 56, 44791, Bochum, Germany.
    Hidradenitis suppurativa (HS) has been associated with marked inflammatory perturbation. The mechanisms regulating the inflammatory network remain elusive. microRNAs (miRNAs) have been described as gene regulators of inflammation. Read More

    Metastatic Squamous Cell Carcinoma of the Pleura: A Rare Complication of Hidradenitis Suppurativa.
    Am J Case Rep 2016 Dec 28;17:989-992. Epub 2016 Dec 28.
    Division of Pulmonary, Critical Care and Sleep Medicine, University of Tennessee Health Sciences Center, Memphis, TN, USA.
    BACKGROUND Squamous cell carcinoma (SCC), also known as Marjolin ulcer, is a rare complication of hidradenitis suppurativa (HS). Metastatic SCC from HS typically involves the axial skeleton or abdominopelvic viscera. Metastatic disease to the lungs is a rare phenomenon with only three reported cases of lung parenchyma. Read More

    Patient Satisfaction and Quality of Life Following Surgery for Hidradenitis Suppurativa.
    Dermatol Surg 2017 Jan;43(1):125-133
    *Mayo Medical School, Mayo Clinic College of Medicine, Rochester, Minnesota;†Department of Dermatology, Mayo Clinic, Rochester, Minnesota;‡Division of Colon and Rectal Surgery, Mayo Clinic, Rochester, Minnesota;§Division of Plastic and Reconstructive Surgery, Mayo Clinic, Rochester, Minnesota.
    Background: Hidradenitis suppurativa (HS) is a progressive, recurrent inflammatory disorder.

    Objective: To assess long-term satisfaction and postoperative perceptions among patients who underwent surgical management of HS.

    Materials And Methods: A questionnaire was mailed to 499 HS surgical patients to assess surgical outcome, satisfaction, and quality of life. Read More

    Autoinflammatory Disease Damage Index (ADDI): a possible newborn also in hidradenitis suppurativa daily practice.
    Ann Rheum Dis 2016 Dec 23. Epub 2016 Dec 23.
    Dipartimento di Fisiopatologia Medico-Chirurgica e dei Trapianti, Universita' degli Studi di Milano, Unita' Operativa di Dermatologia, IRCCS Fondazione Ca' Granda, Ospedale Maggiore Policlinico, Milano, Italy.

    Diagnosing liver fibrosis; a narrative review of current literature for dermatologists.
    Br J Dermatol 2016 Dec 20. Epub 2016 Dec 20.
    St John's Institute of Dermatology, Guys and St Thomas' NHS Foundation Trust.
    Chronic liver disease is a growing problem worldwide due to obesity, alcohol-related liver disease and viral hepatitis. Liver fibrosis is generally asymptomatic and patients may not present until they have advanced cirrhosis, when the scope for reversibility is limited. Identification of asymptomatic individuals at an early stage, is fundamental to reversing the rising toll of liver-related morbidity and mortality. Read More

    SAPHO syndrome in childhood. A case report.
    Reumatol Clin 2016 Dec 16. Epub 2016 Dec 16.
    Unidad de Gestión Clínica de Pediatría, Hospital Universitario San Cecilio, Granada, España.
    The acronym of SAPHO syndrome (synovitis, acne, pustulosis, hyperostosis and osteitis) combines a cluster of cutaneous and musculoskeletal manifestations, such as hyperostosis of bones of the anterior chest wall associated with acne fulminans and hidradenitis suppurativa. There are no validated diagnostic criteria in children. Nonsteroidal anti-inflammatory drugs are not always sufficient, and the use of corticosteroids, disease-modifying agents, tumor necrosis factor-α inhibitors or bisphosphonates may be necessary. Read More

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