3,783 results match your criteria Hidradenitis Suppurativa


Unmet Medical Needs in Chronic, Non-communicable Inflammatory Skin Diseases.

Front Med (Lausanne) 2022 9;9:875492. Epub 2022 Jun 9.

Department of Dermatology, University of Lübeck, Lübeck, Germany.

An estimated 20-25% of the population is affected by chronic, non-communicable inflammatory skin diseases. Chronic skin inflammation has many causes. Among the most frequent chronic inflammatory skin diseases are atopic dermatitis, psoriasis, urticaria, lichen planus, and hidradenitis suppurativa, driven by a complex interplay of genetics and environmental factors. Read More

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[Translated article] RF - Usefulness of Zinc Gluconate and Other Nondrug Treatments for Managing Hidradenitis Suppurativa.

Actas Dermosifiliogr 2022 Jun 26;113(6):T627-T631. Epub 2022 Apr 26.

Departamento de Dermatología, Hospital Clínic de Barcelona, Universitat de Barcelona, Barcelona, Spain. Electronic address:

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Immuno-Pathogenesis of Chronic Inflammatory Skin Diseases: Novel Molecular Targets and Biomarkers.

Life (Basel) 2022 Jun 15;12(6). Epub 2022 Jun 15.

Department of Medicine, Surgery and Dentistry, "Scuola Medica Salernitana", University of Salerno, 84081 Baronissi, SA, Italy.

Chronic inflammation has a crucial pathogenetic role in many diseases, including cutaneous chronic inflammatory disorders, such as psoriasis, atopic dermatitis, hidradenitis suppurativa, and chronic urticaria [... Read More

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Biologics and Small Molecule Inhibitors for Treating Hidradenitis Suppurativa: A Systematic Review and Meta-Analysis.

Biomedicines 2022 Jun 2;10(6). Epub 2022 Jun 2.

Department of Dermatology, Chang Gung Memorial Hospital, Linkou Main Branch, No. 5, Fuxing Street Guishan District, Taoyuan City 333423, Taiwan.

Background: The treatment guidelines for hidradenitis suppurativa (HS) vary among different countries, and several biologics and small molecule inhibitors have been tested for treating moderate-to-severe HS over the past few years. However, treatment guidelines for HS vary among different countries.

Methods: A systematic review and meta-analysis was performed to exam the efficacy and serious adverse events (SAEs) of biologics and small-molecule inhibitors in treating moderate-to-severe HS. Read More

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Infliximab treatment before and after surgery in severe hidradenitis suppurativa: A retrospective study of 10 patients.

Ann Dermatol Venereol 2022 Jun 20. Epub 2022 Jun 20.

Dermatology Department, Hôpital Saint-Louis, AP-HP, and Université de Paris, 75010 Paris, France. Electronic address:

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Biologic Use in Hidradenitis Suppurativa: Patient Perspectives and Barriers.

J Dermatolog Treat 2022 Jun 23:1-4. Epub 2022 Jun 23.

University of Arkansas for Medical Sciences, Department of Dermatology, Little Rock, AR, USA.

Introduction: Hidradenitis suppurativa (HS) is an inflammatory dermatosis for which the treatment paradigm is rapidly expanding. We aimed to identify HS patient perspectives and barriers on biologics.

Methods: An anonymous survey was distributed between 10/2021 to 1/2022 through HS support groups. Read More

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[Chilean clinical guideline for the management of hidradenitis suppurativa - executive summary].

Rev Med Chil 2021 Nov;149(11):1620-1635

Servicio de Dermatología, Hospital de Linares, Linares, Chile.

Hidradenitis suppurativa is a chronic inflammatory disease of the hair follicle characterized by recurrent painful and inflamed lesions, predominantly affecting intertriginous regions. Due to its physical sequelae and impact on quality of life, we should be familiarized with this disease to make an appropriate diagnosis and implement an early treatment. This executive summary of the clinical guideline, elaborated by the hidradenitis suppurativa workgroup of the Chilean Society of Dermatology and Venereology (SOCHIDERM), reviews its definition, epidemiology, pathophysiology, risk factors, comorbidities, psycho-emotional impact, clinical presentation, diagnosis, classifications, ultrasonographic evaluation, and its medical and surgical treatments. Read More

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November 2021

How to Define Mild to Severe Hidradenitis Suppurativa? A Simple New Tool Based on Latent Class Analysis of EPIVER Data Study.

Clin Cosmet Investig Dermatol 2022 16;15:1091-1103. Epub 2022 Jun 16.

ResoVerneuil, Ville, France.

Purpose: Hidradenitis suppurativa (HS) is an inflammatory skin disease characterized by recurrent or chronic painful and suppurating lesions in the apocrine gland-bearing regions. The lack of knowledge about HS and its extremely heterogeneous clinical presentation, in terms of both lesion appearance and sites of involvement, frequently delay its diagnosis for several years. Objectives: in this study, using the latent class analysis, it was demonstrated that severity of HS could be evaluated not only with clinical or surgical characteristics but also with gender specificities. Read More

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RF - Usefulness of Zinc Gluconate and Other Nondrug Treatments for Managing Hidradenitis Suppurativa.

Actas Dermosifiliogr 2022 Jun 16;113(6):627-631. Epub 2021 Nov 16.

Departamento de Dermatología, Hospital Clínic de Barcelona, Universitat de Barcelona, Barcelona, España. Electronic address:

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Menopause, skin and common dermatosis: part 2.

Clin Exp Dermatol 2022 Jun 21. Epub 2022 Jun 21.

Department of Dermatology, University Hospitals Sussex NHS Foundation Trust, Brighton, UK.

Menopause, and the associated hypo-oestrogen state, has implications on the structure and function of the skin. We performed a literature review to investigate the impact of the menopause on common dermatosis. There is evidence that oestrogen is implicated in transepidermal water loss and dermal collagen. Read More

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Management of patients with hidradenitis suppurativa during COVID-19 vaccination: An experience from Southern Italy.

Clin Exp Dermatol 2022 Jun 21. Epub 2022 Jun 21.

Dermatology Unit, Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy.

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Interviewing Women with Hidradenitis Suppurativa-Thematic and Content Analysis.

Adv Skin Wound Care 2022 Jul;35(7):381-384

Shani Fisher, MA, RN, is Chief Nurse in the Dermatology and Venereology Department, Emek Medical Center, Afula, Israel, and the Department of Nursing, Steyer School of Health Professions, Sackler School of Medicine, Tel Aviv University, Israel. Michael Ziv, MD, is Head of Department, Dermatology and Venereology Department, Emek Medical Center. The authors have disclosed no financial relationships related to this article. Submitted July 21, 2021; accepted in revised form August 11, 2021.

Objective: Hidradenitis suppurativa (HS) is a chronic autoinflammatory skin disease with a higher prevalence in women. The disease results in a low quality of life as well as physical and psychological comorbidities. The authors sought to determine the effects of HS on women's self-perception and life experiences. Read More

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Case Report: Comorbid Hyper-IgD Syndrome and Hidradenitis Suppurativa - A New Syndromic Form of HS? A Report of Two Cases.

Front Immunol 2022 26;13:883811. Epub 2022 May 26.

ResoVerneuil, Paris, France.

Hidradenitis Suppurativa (HS) is a chronic suppurative disease of the pilosebaceous unit. The current model of HS pathophysiology describes the condition as the product of hyperkeratinisation and inflammation at the hair follicular unit. Environmental factors (such as smoking and obesity), gender, genetic predisposition, and skin dysbiosis are considered the main pathogenic drivers of the disease. Read More

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Occurrence of inflammatory bowel disease in patients with chronic inflammatory skin diseases: a cohort study.

Br J Dermatol 2022 Jun 19. Epub 2022 Jun 19.

Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.

Background: Several studies linked various chronic inflammatory skin diseases (CISDs) with inflammatory bowel disease (IBD) in a range of data sources with mixed conclusions.

Objective: We compared the incidence of IBD-ulcerative colitis (UC) and Crohn's disease (CD)- in patients with a CISD versus similar persons without a CISD.

Methods: In this cohort study using nationwide, longitudinal, commercial insurance claims data from the US, we identified adults and children who were seen by a dermatologist between 2004-2020, and diagnosed with either psoriasis, atopic dermatitis, alopecia areata, vitiligo, or hidradenitis suppurativa. Read More

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Systematic review of photodynamic therapy for the treatment of hidradenitis suppurativa.

Photodermatol Photoimmunol Photomed 2022 Jun 17. Epub 2022 Jun 17.

Department of Dermatology, University of Minnesota,Minnesota, Minneapolis, MN, U.S.A.

Objective: To perform a systematic review of available literature regarding the use of 5-aminolevulinic acid (ALA) and ALA derivative photodynamic therapy (PDT) in the treatment of hidradenitis suppurativa (HS) and provide recommendations on its use.

Methods: A systematic review was performed of all published studies up to September 1, 2019 from nine databases, including pubmed, that evaluated PDT in the treatment of HS. For each study, quality of evidence and risk of bias was evaluated. Read More

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Microbial Isolates and Association with Disease Severity and Quality of Life in Individuals with Hidradenitis Suppurativa: An Observational Study.

Skin Appendage Disord 2022 May 17;8(3):211-220. Epub 2022 Mar 17.

Directorate of Infection, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom.

Introduction: Hidradenitis suppurativa (HS) is a chronic inflammatory disease characterized by recurrent nodules, abscesses, and sinus tracts, resulting in scarring. Patients suffer significantly impacted quality of life (QoL), manifested by anxiety and depression. We describe microbial isolates identified from active sites in adults with HS, and explore associations between organisms isolated, disease severity, and QoL. Read More

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A Case of Pemphigus Vulgaris and Hidradenitis Suppurativa: May Systemic Steroids Be Considered in the Standard Management of Hidradenitis Suppurativa?

Skin Appendage Disord 2022 May 26;8(3):265-268. Epub 2022 Jan 26.

Department of Clinical Medicine and Surgery, Section of Dermatology, University Hospital Federico II of Naples, Naples, Italy.

Introduction: Recent studies have demonstrated a correlation between pemphigus and hidradenitis suppurativa (HS).

Case Presentation: Here, we report the case of a 58-year-old man affected by HS for about 30 years who was found to have lesions attributable to pemphigus during a checkup.

Discussion/conclusion: There are few data in the literature on the use of systemic corticosteroids for the two diseases, and our article wants to be a food for thought on the management and treatment of these diseases. Read More

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Neutrophilic Dermatoses in a Clinical Practice of Wound Care Professionals.

Adv Skin Wound Care 2022 Jun;35(6):1-8

Tatiana Lapa, MD, MScCH, is Master's Student, Dalla Lana School of Public Health, University of Toronto, Clinical Practicum Placement, Toronto Regional Wound Healing Clinic, International Interprofessional Wound Care Course, Toronto, Ontario, Canada. R. Gary Sibbald, MD, DSc (Hons), MEd, BSc, FRCPC (Med Derm), MACP, FAAD, MAPWCA, is Professor, Division of Dermatology, Department of Medicine, and Dalla Lana School of Public Health, University of Toronto, and Women's College Hospital, Toronto. Patricia M. Coutts, RN, is Wound Care & Clinical Trials Coordinator, Toronto Regional Wound Healing Clinic and Faculty, International Interprofessional Wound Care Course. Xiu Chang Zhao, MD, CCFP, is Family Physician, Trillium Health Partners, Mississauga, Ontario. The authors have disclosed no financial relationships related to this article. Submitted June 7, 2021; accepted in revised form July 26, 2021.

Abstract: Diagnosing and treating neutrophilic dermatoses (NDs) in clinical practice can be challenging because of various presentations and stubborn treatment responses. Establishing a diagnosis is necessary, though, because many NDs are associated with underlying conditions, including malignancy. In this article, the authors provide information about Sweet syndrome, pyoderma gangrenosum, and other NDs and describe their clinical presentation, pathophysiology, diagnostic criteria, and associated conditions. Read More

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A Case of Overlapping Clinical Features of Idiopathic Granulomatous Mastitis, Hidradenitis Suppurativa, and Pyoderma Gangrenosum Successfully Treated with Adalimumab.

Case Rep Dermatol 2022 May-Aug;14(2):98-106. Epub 2022 May 3.

Department of Dermatovenerology, University Medical Centre Maribor, Maribor, Slovenia.

A 36-year-old woman with a 6-month history of painful unilateral mammary nodules and abscesses was initially treated by gynecologists under the diagnosis of idiopathic granulomatous mastitis (IGM). IGM is an entity that has not been described in classical dermatological textbooks and is considered a rare inflammatory breast disease assumingly associated with trauma, infection, or autoimmune system manifestations. In this patient, the lesions were refractory to conventional treatment of IGM comprising of surgical incisions, systemic antibiotics, dexamethasone, and methotrexate. Read More

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Acne Fulminans Induced by Lymecycline in a Patient with Hidradenitis Suppurativa: A Case Report.

Case Rep Dermatol 2022 May-Aug;14(2):112-116. Epub 2022 May 9.

Section of Dermatology, Department of Health Sciences, University of Genoa, IRCCS, Genoa, Italy.

Acne fulminans (AF) is a rare and severe form of inflammatory acne that typically occurs in male adolescents with acne vulgaris and is characterized by the sudden onset of painful, bleeding, and ulcerated lesions. It has been described very rarely in association with hidradenitis suppurativa (HS). Its onset may be induced by drugs, particularly isotretinoin. Read More

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Patients with Hidradenitis Suppurativa Suffer from Low Health-Related Quality of Life as Measured by the Generic 15D Instrument.

Skin Appendage Disord 2022 May 27;8(3):221-227. Epub 2021 Dec 27.

Department of Dermatology and Medical Research Center Oulu, Oulu University Hospital, PEDEGO Research Unit, University of Oulu, Oulu, Finland.

Introduction: Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease associated with various comorbidities and diminished quality of life (QoL). Among dermatological conditions, HS is reported to most severely diminish QoL. This study aimed to analyse the health-related QoL (HRQoL) of patients with HS in more detail by using generic to disease-specific HRQoL questionnaires. Read More

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Clostridium difficile infection risk in hidradenitis suppurativa patients.

Br J Dermatol 2022 Jun 14. Epub 2022 Jun 14.

Department of Dermatology, University of North Carolina at Chapel Hill, NC, USA.

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Potential use of microwave technology in dermatology.

J Dermatolog Treat 2022 Jun 20:1-11. Epub 2022 Jun 20.

Mediprobe Research Inc, London, Ontario, Canada.

Background: Microwaves are used in medicine for diagnostics, and treatment of cancer. Recently, novel microwave devices (Swift, Emblation Ltd, UK and miraDry, Miramar Labs Inc., CA) have been cleared by the FDA and Health Canada for various dermatological conditions. Read More

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Tacrolimus ointment may improve the effectiveness of Adalimumab in patients affected by hidradenitis suppurativa: a novel promising treatment.

Clin Exp Dermatol 2022 Jun 14. Epub 2022 Jun 14.

Section of Dermatology, Department of Clinical Medicine and Surgery, University of Naples Federico II, Italy.

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Systemic immune inflammation index is a marker of cardiovascular risk and not just disease severity in hidradenitis suppurativa.

J Eur Acad Dermatol Venereol 2022 Jun 13. Epub 2022 Jun 13.

Department of Dermatology, St. Vincent's University Hospital, Dublin, Ireland.

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