2,105 results match your criteria Hidradenitis Suppurativa


[Gynecological aspects of hidradenitis suppurativa].

Orv Hetil 2019 Feb;160(8):291-299

Bőr-, Nemikórtani és Bőronkológiai Klinika, Semmelweis Egyetem, Általános Orvostudományi Kar Budapest, Mária u. 41., 1085.

Hidradenitis suppurativa is a chronic inflammatory disease of the hair follicles, usually presenting after puberty on the apocrine gland-bearing areas of the body. It usually flares up periodically and can lead to a severe condition affecting the 20-40-year-old childbearing age group. HS occurs more commonly in women. Read More

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http://dx.doi.org/10.1556/650.2019.31319DOI Listing
February 2019

Response to "Korean gender differences in hidradenitis suppurativa: nature or nurture?"

J Eur Acad Dermatol Venereol 2019 Feb 14. Epub 2019 Feb 14.

Department of Dermatology, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Suwon, Korea.

We thank R. Happle for his invaluable comments on our recent article regarding the prevalence of hidradenitis suppurativa (HS) in Korea. We agree with the opinion that the low prevalence of HS in Korean women may be due to the low number of female smokers in Korea. Read More

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http://dx.doi.org/10.1111/jdv.15500DOI Listing
February 2019

Korean gender differences in hidradenitis suppuratva: nature or nurture?

Authors:
R Happle

J Eur Acad Dermatol Venereol 2019 Feb 14. Epub 2019 Feb 14.

Department of Dermatology, Medical Center - University of Freiburg, Germany.

In a recent population-based study on hidradenitis suppurativa (HS) in Korea, Lee et al. found that the female to male ratio was 1:1.6. Read More

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http://dx.doi.org/10.1111/jdv.15507DOI Listing
February 2019

Understanding the long diagnostic delay for hidradenitis suppurativa: a national survey among French general practitioners.

Eur J Dermatol 2019 Feb 11. Epub 2019 Feb 11.

CHRU Tours, Department of Dermatology, 37044 Tours,, Universities of Tours and Nantes, SPHERE-INSERM 1246.

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http://dx.doi.org/10.1684/ejd.2018.3478DOI Listing
February 2019
1 Read

Secukinumab and hidradenitis suppurativa: Friends or foes?

JAAD Case Rep 2019 Feb 30;5(2):184-187. Epub 2019 Jan 30.

Departments of Clinical Medicine and Surgery, Section of Dermatology, University of Naples Federico II, Naples, Italy.

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http://dx.doi.org/10.1016/j.jdcr.2018.12.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357542PMC
February 2019
3 Reads

Overall and Subgroup Prevalence of Pyoderma Gangrenosum Among Patients with Hidradenitis Suppurativa: a population based analysis in the United States.

J Am Acad Dermatol 2019 Feb 6. Epub 2019 Feb 6.

Department of Dermatology, Donald and Barbara Zucker School of Medicine at Hofstra Northwell. New Hyde Park, NY, USA. Electronic address:

Background: Hidradenitis suppurativa (HS) and pyoderma gangrenosum (PG) are reported to coexist, although prevalence of PG among HS patients has not been systematically evaluated.

Objective: To evaluate PG prevalence among HS patients.

Methods: Cross-sectional analysis of adults with PG among HS and non-HS patients using electronic health records data from a population-based sample of 55 million patients. Read More

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http://dx.doi.org/10.1016/j.jaad.2019.02.004DOI Listing
February 2019
1 Read

A case report of severe recurrent varicella in an ankylosing spondylitis patient treated with adalimumab - a new side effect after 15 years of usage.

BMC Infect Dis 2019 Feb 7;19(1):127. Epub 2019 Feb 7.

University Hospital for Infectious Diseases "Dr. Fran Mihaljević", Mirogojska 8, 10000, Zagreb, Croatia.

Background: Tumor necrosis factor-α (TNF-α) antagonists, most of which are monoclonal antibodies, became a widespread treatment for autoimmune diseases such as rheumatoid arthritis, ankylosing spondylitis, inflammatory bowel diseases, psoriasis, psoriatic arthritis, hidradenitis suppurativa and uveitis. Their use is based on the blockage of TNF-α, which plays an important role in granulomas formation, development of phagosomes, activation and differentiation of macrophages, immune response against viral pathogens. The multiple adverse effects of TNF-α inhibition have been identified, including a two-to four-fold increased risk of active tuberculosis and other granulomatous conditions and an increased occurrence of some other serious bacterial, fungal and certain viral infections. Read More

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https://bmcinfectdis.biomedcentral.com/articles/10.1186/s128
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http://dx.doi.org/10.1186/s12879-019-3768-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367735PMC
February 2019
2 Reads

Hidradenitis suppurativa and diabetes mellitus: updated systematic review and adjusted meta-analysis.

Clin Exp Dermatol 2019 Feb 7. Epub 2019 Feb 7.

Department of Dermatology, Royal North Shore Hospital, St Leonards, Sydney, Australia.

Background: Hidradenitis suppurativa (HS) is a debilitating and distressing chronic inflammatory skin disease. There is also evolving evidence supporting the association between HS and cardiovascular risk factors, including smoking, obesity, hyperlipidaemia and metabolic syndrome. Notably, these are clinical features and risk factors that are closely associated with type 2 diabetes mellitus (DM). Read More

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http://doi.wiley.com/10.1111/ced.13922
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http://dx.doi.org/10.1111/ced.13922DOI Listing
February 2019
2 Reads

Preoperative Ultrasound for Evaluation of Hidradenitis Suppurativa.

Dermatol Surg 2019 Feb;45(2):294-296

Department of Dermatology, Henry Ford Hospital System, Detroit, Michigan.

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http://dx.doi.org/10.1097/DSS.0000000000001696DOI Listing
February 2019

Interrater agreement and reliability of outcome measurement instruments and staging systems used in hidradenitis suppurativa.

Br J Dermatol 2019 Feb 6. Epub 2019 Feb 6.

Department of Dermatology, Zealand University Hospital, Roskilde, Health Sciences Faculty, University of Copenhagen, Denmark.

Background: Monitoring disease activity over time is a prerequisite for clinical practice and research. Valid and reliable outcome measurements instruments (OMIs) and staging systems provide researchers and clinicians with benchmark tools to assess the primary and secondary outcomes of interventional trials and to guide treatment selection properly.

Objectives: To investigate interrater reliability and agreement in instruments currently used in Hidradenitis Suppurativa (HS) with HS-experienced dermatologists being the rater population of interest. Read More

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http://dx.doi.org/10.1111/bjd.17716DOI Listing
February 2019

Could Isotretinoin flare Hidradentis suppurativa? A Case Series.

Clin Exp Dermatol 2019 Feb 5. Epub 2019 Feb 5.

Department of Dermatology, Tallaght University Hospital, Tallaght, Dublin 24, Ireland.

We report eight cases of patients with severe acne who were treated with Isotretinoin and developed painful nodules in their axillae and groin consistent with Hidradenitis Suppurativa (HS). The pathogenesis of HS is still not completely understood; recent research from a study in 2011 of biopsies from HS lesions showed a reduction or absence of sebaceous glands compared to normal skin in HS patients and the author suggested this contributes to the pathogenesis of the disease Interestingly the main effect of Isotretinoin is to decrease the size and action of sebaceous glands; so hypothetically, as Isotretinoin acts by reducing the sebaceous glands further it could potentially aggravate the condition. Our experience has instilled caution in our prescribing of Isotretinoin; patients are questioned about symptoms of HS prior to and during treatment, particularly patients with acne conglobata. Read More

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http://dx.doi.org/10.1111/ced.13944DOI Listing
February 2019

Biologics for hidradenitis suppurativa: an update.

Immunotherapy 2019 Jan;11(1):45-59

Department of Dermatology, Venereology & Allergology, Medical University, Wroclaw, Poland.

Hidradenitis suppurativa (HS) is a chronic, inflammatory dermatosis characterized by an occurrence of nodules, abscesses, sinus tracks and scarring. Its pathogenesis is multifactorial and still not fully understood, therefore, current systemic therapies still remain a serious challenge. Increased levels of several proinflammatory cytokines have been reported in patients suffering from HS, therefore biologics appear as a new approach to therapy for this condition. Read More

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https://www.futuremedicine.com/doi/10.2217/imt-2018-0090
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http://dx.doi.org/10.2217/imt-2018-0090DOI Listing
January 2019
4 Reads

Association Between Hidradenitis Suppurativa and Lymphoma.

JAMA Dermatol 2019 Jan 30. Epub 2019 Jan 30.

Department of Dermatology, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, New Hyde Park, New York.

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http://dx.doi.org/10.1001/jamadermatol.2018.5230DOI Listing
January 2019

Two cases of Hidradenitis suppurativa and botulinum toxin type a therapy: A novel approach for a pathology that is still difficult to manage.

Dermatol Ther 2019 Jan 28:e12841. Epub 2019 Jan 28.

Dermatology Unit, Department of Clinical and Molecular Sciences, Polytechnic Marche University, Ancona, Italy.

Hidradenitis suppurativa is a chronic skin disease with an intense inflammatory activation. It typically affects the intertriginous areas with cysts, fistulae, and scarring extremely painful. Patients suffer from severe psychological impact. Read More

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http://dx.doi.org/10.1111/dth.12841DOI Listing
January 2019

Inter-Relater Reliability of Phenotypes, and Exploratory Genotype- Phenotype Analysis in Inherited Hidradenitis Suppurativa.

Br J Dermatol 2019 Jan 28. Epub 2019 Jan 28.

Laboratory for Investigative Dermatology, The Rockefeller University, New York, NY.

Background: Genotype-phenotype correlation is a statistical relationship that measures correlation between the presence of a physical trait with a group of similar mutations but is dependent upon reliable phenotyping. It can provide information regarding disease pathogenesis, future disease progression, severity or activity. Such indicators would be valuable in Hidradenitis Suppurativa. Read More

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http://dx.doi.org/10.1111/bjd.17695DOI Listing
January 2019

Investigation of the Skin Microbiome: Swabs vs Biopsies.

Br J Dermatol 2019 Jan 28. Epub 2019 Jan 28.

Imperial College, London, United Kingdom.

Background: Human skin is populated by diverse bacteria and there is increasing evidence that resident bacteria play a key role initiating immune responses in cutaneous diseases such as atopic dermatitis, psoriasis and hidradenitis suppurativa. Bacteria are present at all layers of the skin but many studies have relied on swabs to profile the skin microbiota. As the pathogenesis of many skin conditions is dermal, we wished to compare the microbiota obtained in swabs (surface) and biopsies (dermis). Read More

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http://dx.doi.org/10.1111/bjd.17691DOI Listing
January 2019

Infiltrative squamous cell carcinoma in hidradenitis suppurativa: A case report for early surgical intervention.

Int J Surg Case Rep 2019 Jan 19;55:50-53. Epub 2019 Jan 19.

Department of Surgery, University of Rochester School of Medicine and Dentistry, Rochester, NY, 14642-0001, USA.

Introduction: Hidradenitis suppurativa (HS) is a chronic inflammatory disease of the skin that has potential for malignant transformation into squamous cell carcinoma (SCC). The pathogenesis of HS is poorly understood but thought to be from follicular keratinization, occlusion, and rupture of the pilosebaceous unit, followed by an infiltration of inflammatory cells into the dermis. Treatment is challenging due to a lack of effective medical therapies. Read More

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http://dx.doi.org/10.1016/j.ijscr.2019.01.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351348PMC
January 2019
2 Reads

The Refined Hurley Patient Questionnaire: An Accurate Self-assessment Instrument for Deriving the Correct Refined Hurley Stage in Hidradenitis Suppurativa.

Acta Derm Venereol 2019 01 23. Epub 2019 Jan 23.

Department of Dermatology, University Medical Center Groningen, NL-9700 RB Groningen, The Netherlands.

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http://dx.doi.org/10.2340/00015555-3126DOI Listing
January 2019

Successful treatment of stage III hidradenitis suppurativa with botulinum toxin A.

BMJ Case Rep 2019 Jan 20;12(1). Epub 2019 Jan 20.

Physical Medicine and Rehabilitation, Penn State Health Milton S Hershey Medical Center, Hershey, Pennsylvania, USA.

A 41-year-old obese Native American woman presented with hidradenitis suppurativa (HS) after failing all available treatment options. Her HS was more pronounced in the axillary and groin regions (Hurley stage III) and was a major source of her pain and a barrier for home exercise and aquatic therapy. She received a botulinum toxin A injection every 3 months (four times thus far), which has significantly helped alleviate her pain and curb the progress of her HS by resolving abscesses and healing draining sinuses. Read More

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http://dx.doi.org/10.1136/bcr-2018-226064DOI Listing
January 2019
1 Read

Hidradenitis Suppurativa is Associated with Higher Heart Rate but Not Atrial Fibrillation: A Comparative Cross-sectional Study of 462 Individuals with Hidradenitis Suppurativa in Denmark.

Acta Dermatovenerol Croat 2018 Dec;26(4):289-296

Iben Marie Miller, MD, Department of Dermatology, Roskilde Hospital, Køgevej 7-13, 4000 Roskilde, Denmark;

Hidradenitis suppurativa (HS) is a chronic inflammatory dermatological disease with inflammatory mechanisms overlapping those of psoriasis, and both diseases have been associated with cardiovascular risk factors i.e. smoking and metabolic syndrome. Read More

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December 2018
4 Reads

Combination Therapies for Hidradenitis Suppurativa: A Retrospective Chart Review of 31 Patients.

J Cutan Med Surg 2019 Jan 18:1203475418823529. Epub 2019 Jan 18.

2 Division of Dermatology, Faculty of Medicine, University of Ottawa and The Ottawa Hospital, ON, Canada.

Background:: Although a variety of medical and surgical interventions exist for the treatment of hidradenitis suppurativa (HS), it remains a challenging disease to manage because of its variable presentation and unpredictable clinical course. Apart from the combination of clindamycin and rifampin, the success of other combination therapies is largely unknown.

Objectives:: The goal of our study was to examine the clinical utility of various combination therapies for the treatment of HS. Read More

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http://dx.doi.org/10.1177/1203475418823529DOI Listing
January 2019
5 Reads

Bacterial biofilm is associated with higher levels of regulatory T-cells in unaffected hidradenitis suppurativa skin.

Exp Dermatol 2019 Jan 18. Epub 2019 Jan 18.

Departments of Dermatology University Hospital Zealand, Roskilde.

Background: The role of bacterial biofilm in hidradenitis suppurativa (HS) is highly debated. Less biofilm is found in clinically unaffected axillary perilesional skin of HS patients compared with healthy controls.

Objective: To study the correlation between biofilm and the phenotypical characterization of the pre-clinical inflammatory infiltrate. Read More

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http://dx.doi.org/10.1111/exd.13885DOI Listing
January 2019
1 Read

Altered NOX expression does not seem to account for epidermal NLRP3 inflammasome activation in Hidradenitis Suppurativa.

Br J Dermatol 2019 Jan 18. Epub 2019 Jan 18.

Department of Dermatology, Venereology and Allergology, University Hospital Würzburg, Germany.

Hidradenitis Suppurativa (HS)/ acne inversa is defined as a chronic, inflammatory, recurrent, debilitating skin disease of the hair follicle that usually presents after puberty with painful, deep-seated, inflamed lesions in the apocrine gland-bearing areas of the body, most commonly the axillae, inguinal and anogenital regions (Dessau definition). It is associated with systemic comorbidities and influenced by genetic predisposition while triggering of the disease occurs by environmental factors. Consecutively, innate immune events appear to play a role. Read More

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http://doi.wiley.com/10.1111/bjd.17647
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http://dx.doi.org/10.1111/bjd.17647DOI Listing
January 2019
5 Reads

The anti-inflammatory potency of biologics targeting TNF-α, IL-17A, IL-12/23 and CD20 in hidradenitis suppurativa: an ex vivo study.

Br J Dermatol 2019 Jan 18. Epub 2019 Jan 18.

Department of Dermatology, Erasmus University Medical Center, Rotterdam, The Netherlands.

Background: Biologics targeting inflammatory mediators are able to clinically improve hidradenitis suppurativa (HS). However, their clinical efficacy shows great inter-patient variability in daily practice.

Objective: To investigate the anti-inflammatory potency of a selection of currently available biologics for the treatment of HS in an ex vivo skin culture system using lesional HS biopsies. Read More

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http://dx.doi.org/10.1111/bjd.17641DOI Listing
January 2019
2 Reads

Nicastrin haploinsufficiency alters expression of type I interferon-stimulated genes: the relationship to familial hidradenitis suppurativa.

Clin Exp Dermatol 2019 Jan 17. Epub 2019 Jan 17.

Department of Medicine, Division of Rheumatology, Washington University, St Louis, MO, USA.

Background: Hidradenitis suppurativa (HS), also called acne inversa, is a chronic skin disease. The symptoms can be severe, and include intensely painful nodules and abscesses in apocrine-gland rich inverse skin, such as the buttocks, under the arms and in the groin. Autosomal dominant forms of HS exist, but are rare. Read More

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http://doi.wiley.com/10.1111/ced.13906
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http://dx.doi.org/10.1111/ced.13906DOI Listing
January 2019
4 Reads

Long-Wave Medical Infrared Thermography: A Clinical Biomarker of Inflammation in Hidradenitis Suppurativa/Acne Inversa.

Dermatology 2019 Jan 16:1-6. Epub 2019 Jan 16.

Departments of Dermatology, Venereology, Allergology and Immunology, Dessau Medical Center, Brandenburg Medical School Theodor Fontane, Dessau, Germany.

Background: A more reliable classification of skin inflammation and severity of active disease results from ultrasound sonography and the new hidradenitis suppurativa/acne inversa (HS) classification system IHS4. However, an objective assessment of skin inflammation in a continuous mode is still the ultimate goal. Long-wave medical infrared thermography (MIT) may offer a blood flow and temperature differential assessment in inflammatory conditions. Read More

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https://www.karger.com/Article/FullText/495982
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http://dx.doi.org/10.1159/000495982DOI Listing
January 2019
5 Reads

Hidradenitis suppurativa - known and unknown disease.

Reumatologia 2018 23;56(6):337-339. Epub 2018 Dec 23.

Department of Dermatology, Medical Centre for Postgraduate Education, Central Hospital of Ministry of Internal Affairs, Warsaw, Poland.

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http://dx.doi.org/10.5114/reum.2018.80709DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330680PMC
December 2018

Long-Term Outcome of Adalimumab in a Young Girl with Hidradenitis Suppurativa.

Skin Appendage Disord 2018 Nov 11;5(1):38-41. Epub 2018 Apr 11.

Department of Dermatology, University of Pisa, Pisa, Italy.

Hidradenitis suppurativa (HS) is a chronic, burdensome inflammatory skin disorder mainly affecting adults with an infrequent onset during childhood or adolescence. Guidelines regarding the therapeutic drugs in pediatric HS patients are lacking. We describe the case of a 16-year-old girl affected by HS with a massive impact of the disease on her daily activities. Read More

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http://dx.doi.org/10.1159/000487365DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323380PMC
November 2018

Ixekizumab in hidradenitis suppurativa: a case report in a psoriatic patient.

G Ital Dermatol Venereol 2019 Jan 9. Epub 2019 Jan 9.

Dermatology Unit, Department of Surgical, Medical, Dental and Morphological Sciences with Interest Transplant, Oncological and Regenerative Medicine, University of Modena and Reggio Emilia, Modena, Italy.

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https://www.minervamedica.it/index2.php?show=R23Y9999N00A190
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http://dx.doi.org/10.23736/S0392-0488.18.06135-7DOI Listing
January 2019
10 Reads

HIDRAdisk: validation of an innovative visual tool to assess the burden of hidradenitis suppurativa.

J Eur Acad Dermatol Venereol 2019 Jan 11. Epub 2019 Jan 11.

Dipartimento di Medicina Clinica e Specialistica, U.O. di Dermatologia, A.O.U. di Ferrara, Ferrara, Italy.

Background: Hidradenitis suppurativa (HS) is a chronic, relapsing, inflammatory skin disease characterized by painful inflamed nodules, recurrent abscesses, and fistulas located in apocrine gland-bearing body sites. The negative impact of HS on patient's quality of life (QoL) has been reported to be greater than other dermatologic conditions as psoriasis and atopic eczema, and its improvement is an important goal in disease management. Nowadays there are no specific validated QoL instruments available for HS and generic dermatologic questionnaires are used. Read More

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http://doi.wiley.com/10.1111/jdv.15425
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http://dx.doi.org/10.1111/jdv.15425DOI Listing
January 2019
13 Reads

An assessment of the relative impact of hidradenitis suppurativa, psoriasis, and obesity on quality of life.

Int J Womens Dermatol 2018 Dec 11;4(4):198-202. Epub 2018 Oct 11.

Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts.

Background: Hidradenitis suppurativa (HS) and psoriasis are inflammatory skin diseases associated with obesity. Each disease is likely to impact the quality of life of patients, but the relative impact of each disease is unknown.

Objectives: This study aimed to determine whether skin disease or obesity is more distressing to obese patients who have either psoriasis or HS. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S23526475183003
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http://dx.doi.org/10.1016/j.ijwd.2018.08.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322354PMC
December 2018
4 Reads

Metabolic syndrome in dermatology: Treatment and Management for Dermatologists.

Dermatol Ther 2019 Jan 8:e12812. Epub 2019 Jan 8.

Department of Dermatology and Venerology, Cerrahpaşa Medical Faculty, İstanbul University-Cerrahpaşa, İstanbul, Turkey.

Metabolic syndrome, a commonly observed pathology and a global health issue, is closely related to the skin and thus dermatologists. The skin contributes to the development of metabolic syndrome and it is an end organ for it. Metabolic dysfunction is related to many skin disorders, some of which with high association and some of which with lower association. Read More

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http://doi.wiley.com/10.1111/dth.12812
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http://dx.doi.org/10.1111/dth.12812DOI Listing
January 2019
2 Reads

Hidradenitis Suppurativa: A Systematic Review Integrating Inflammatory Pathways Into a Cohesive Pathogenic Model.

Front Immunol 2018 14;9:2965. Epub 2018 Dec 14.

Department of Dermatology, Erasmus University Medical Center, Rotterdam, Netherlands.

The pathogenesis of hidradenitis suppurativa (HS) is not fully understood. This systematic review examined the latest evidence for molecular inflammatory pathways involved in HS as a chronic inflammatory skin disease. A systematic literature search was performed in PubMed/Medline and EMBASE from January 2013 through September 2017, according to the preferred reporting items for systematic reviews and meta-analyses (PRISMA). Read More

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https://www.frontiersin.org/article/10.3389/fimmu.2018.02965
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http://dx.doi.org/10.3389/fimmu.2018.02965DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302105PMC
December 2018
11 Reads

High-frequency ultrasound in hidradenitis suppurativa as rationale for permanent hair laser removal.

Skin Res Technol 2019 Jan 4. Epub 2019 Jan 4.

Dipartimento di Fisiopatologia Medico-Chirurgica e dei Trapianti, Unità Operativa di Dermatologia, Università degli Studi di Milano, IRCCS Fondazione Ca' Granda, Ospedale Maggiore Policlinico, Milano, Italy.

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http://dx.doi.org/10.1111/srt.12671DOI Listing
January 2019
1 Read

Squamous Cell Carcinoma in Perineal, Perianal, and Gluteal Hidradenitis Suppurativa: Experience in 12 Patients.

Dermatol Surg 2018 Dec 24. Epub 2018 Dec 24.

Departments of Dermatology.

Background: Few reports describe squamous cell carcinoma (SCC) arising in hidradenitis suppurativa (HS).

Objective: The 2 objectives were (1) to describe the clinical characteristics, pathologic findings, and postoperative outcomes of SCC in HS and (2) to assess whether human papillomavirus (HPV) is involved in the pathogenesis.

Materials And Methods: Cases of SCC in HS were identified through institutional medical records (1976-2013) and the Rochester Epidemiology Project. Read More

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http://dx.doi.org/10.1097/DSS.0000000000001713DOI Listing
December 2018
2 Reads

Clindamycin alone may be enough. Is it time to abandon rifampicin for hidradenitis suppurativa? Reply from the authors.

Br J Dermatol 2019 Jan 3. Epub 2019 Jan 3.

Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Dermatology, Venerology und Allergy, Division of Evidence-Based Medicine (dEBM)Department of Dermatology, Charité, Berlin.

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http://dx.doi.org/10.1111/bjd.17600DOI Listing
January 2019
1 Read

Clindamycin alone may be enough. Is it time to abandon rifampicin for hidradenitis suppurativa?

Br J Dermatol 2019 Jan 3. Epub 2019 Jan 3.

Dermatology Department, Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy.

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http://dx.doi.org/10.1111/bjd.17597DOI Listing
January 2019
7 Reads

Role of Nutrition and Adherence to the Mediterranean Diet in the Multidisciplinary Approach of Hidradenitis Suppurativa: Evaluation of Nutritional Status and Its Association with Severity of Disease.

Nutrients 2018 Dec 28;11(1). Epub 2018 Dec 28.

Dipartimento di Medicina Clinica e Chirurgia, Unit of Endocrinology, Federico II University Medical School of Naples, Via Sergio Pansini 5, 80131 Naples, Italy.

Hidradenitis suppurativa (HS) is a chronic, inflammatory and debilitating skin disorder. The exacerbating factors of HS include nutrition and adiposity. We aimed to investigate the relationships between body composition and the adherence to the Mediterranean diet (MD) with the severity of HS in a sample of naive-treatment patients with HS. Read More

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http://dx.doi.org/10.3390/nu11010057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356593PMC
December 2018

"Invasive Proliferative Gelatinous Mass" of Hidradenitis Suppurativa contains distinct inflammatory components.

Br J Dermatol 2018 Dec 30. Epub 2018 Dec 30.

Department of Dermatology, The Pennsylvania State University College of Medicine, Hershey, PA.

As defined by the European Dermatology Forum, Hidradenitis Suppurativa (HS) is a chronic, inflammatory skin disease of the hair follicle in the axillae, inguinal and anogenital regions (Fig 1a, top). For severe cases, surgical management of lesions by "deroofing" is helpful. As first described by William Danby, sinus tracts contain an "invasive proliferative gelatinous mass (IPGM)" attached to the sinus tract epithelium[1]. Read More

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http://dx.doi.org/10.1111/bjd.17541DOI Listing
December 2018

Substantially reduced life expectancy in patients with hidradenitis suppurativa: a Finnish nationwide registry study.

Br J Dermatol 2018 Dec 30. Epub 2018 Dec 30.

PEDEGO Research Unit, University of Oulu, Department of Dermatology and Medical Research Center Oulu, Oulu University Hospital, Oulu, Finland.

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http://dx.doi.org/10.1111/bjd.17578DOI Listing
December 2018

Sex-related differences of clinical features in hidradenitis suppurativa: analysis of an Italian-based cohort.

Clin Exp Dermatol 2018 Dec 28. Epub 2018 Dec 28.

Dermatological Unit, Department of Clinical and Molecular Sciences, Polytechnic Marche University, Ancona, Italy.

The clinical characteristics associated with hidradenitis suppurativa (HS) severity are poorly understood. In this study, 124 patients with HS from 6 Italian dermatology centres participated in this study. Disease severity was assessed using the Hidradenitis Suppurativa Physician's Global Assessment score (HS-PGA) and Hurley score. Read More

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http://dx.doi.org/10.1111/ced.13861DOI Listing
December 2018
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Hidradenitis suppurativa.

Authors:
Sunny Baker

JAAPA 2019 Jan;32(1):47-48

Sunny Baker practices emergency medicine at Texas Tech University Medical Center in El Paso, Tex. The author has disclosed no potential conflicts of interest, financial or otherwise.

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http://dx.doi.org/10.1097/01.JAA.0000550296.68348.31DOI Listing
January 2019

Three cases of bacterial osteomyelitis associated with hidradenitis suppurativa.

Br J Dermatol 2018 Dec 26. Epub 2018 Dec 26.

Department of Dermatology, Centre Hospitalier Universitaire de Bordeaux, F-33000, Bordeaux, France.

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http://dx.doi.org/10.1111/bjd.17593DOI Listing
December 2018

Chitinase-3-like Protein 1 (YKL-40) Is Expressed in Lesional Skin in Hidradenitis Suppurativa.

In Vivo 2019 Jan-Feb;33(1):141-143

Department of Dermatology, Venereology and Allergology, Wrocław Medical University, Wrocław, Poland

Background/aim: Hidradenitis suppurativa (HS) is a chronic disease. Recently, we suggested, chitinase-3-like protein 1 (YKL-40) as a new biomarker for HS since its serum levels were found to be elevated in patients. The objective of this study was to examine YKL-40 tissue expression in HS. Read More

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http://dx.doi.org/10.21873/invivo.11450DOI Listing
September 2018
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Navigating Targeted Therapeutics in Dermatology: Biologics and Small Molecules

J Drugs Dermatol 2018 Dec;17(12):1330-1332

Dermatology is entering an exciting era with new, targeted immune-modulating medications for treating a variety of dermatologic conditions including psoriasis, atopic dermatitis (AD), and hidradenitis suppurativa. Previously, mainstay treatments consisted of topical corticosteroids or broad systemic immunosuppressants. Recently, our understanding of cytokine signaling cascades has grown, presenting new opportunities to target skewed immune responses. Read More

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December 2018
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Inter- and Intrarater Reliability of the Hurley Staging for Hidradenitis Suppurativa.

Br J Dermatol 2018 Dec 26. Epub 2018 Dec 26.

Department of Plastic, Reconstructive and Hand Surgery, Amsterdam University Medical Center, University of Amsterdam.

Background: Hidradenitis suppurativa (HS) is a chronic, inflammatory and recurrent skin disease. Different staging instruments have been suggested, but none has achieved universal acceptance. Despite the fact that the Hurley staging is one of the most widely applied HS disease severity staging instruments, it has not been validated. Read More

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http://dx.doi.org/10.1111/bjd.17588DOI Listing
December 2018

MRI evaluation of anal and perianal diseases.

Diagn Interv Radiol 2019 Jan;25(1):21-27

Department of Radiology, Hacettepe University School of Medicine, Ankara, Turkey.

Anal and perianal region is a commonly affected area in the course of several inflammatory, infectious, and neoplastic diseases. Several imaging modalities may be used in imaging evaluation of this area and magnetic resonance imaging (MRI) emerges as the imaging modality of choice due to its superb soft tissue resolution. MRI is not only useful for initial detection of anal/perianal pathologies but also in the follow-up of these disorders. Read More

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http://dx.doi.org/10.5152/dir.2018.17499DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339630PMC
January 2019
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Improving Health Literacy and Treatment Understanding of Hidradenitis Suppurativa using Group Educational Interventions.

J Dermatolog Treat 2018 Dec 22:1-16. Epub 2018 Dec 22.

a Department of Dermatology , Tufts Medical Center , Boston MA.

Background: Hidradenitis suppurativa (HS) is a chronic immune mediated skin disorder characterized by inflamed, painful abscesses most commonly located in the intertriginous regions that may lead to significant scarring and social stigma. It is unclear how much patients with HS understand about their disease.

Objective: We sought to evaluate baseline knowledge of patients who have HS, as well as to evaluate if an educational intervention of a teaching session about the disease will help increase patient's knowledge of their ailment and treatment options. Read More

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http://dx.doi.org/10.1080/09546634.2018.1562536DOI Listing
December 2018
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