1,554 results match your criteria Herpes Zoster Ophthalmicus


Efficacy, effectiveness, and safety of herpes zoster vaccines in adults aged 50 and older: systematic review and network meta-analysis.

BMJ 2018 Oct 25;363:k4029. Epub 2018 Oct 25.

Department of Medicine, University of Toronto, Toronto, ON, Canada.

Objective: To compare the efficacy, effectiveness, and safety of the herpes zoster live attenuated vaccine with the herpes zoster adjuvant recombinant subunit vaccine or placebo for adults aged 50 and older.

Design: Systematic review with bayesian meta-analysis and network meta-analysis.

Data Sources: Medline, Embase, and Cochrane Library (inception to January 2017), grey literature, and reference lists of included studies. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201212PMC
October 2018
10 Reads

More than meets the eye: Varicella zoster virus-related orbital apex syndrome.

Indian J Ophthalmol 2018 Nov;66(11):1647-1649

Department of Internal Medicine, Singapore General Hospital; Department of Ophthalmology, Duke-NUS Medical School, Singapore.

A 67-year-old male patient with poorly controlled type-2 diabetes mellitus developed an orbital apex syndrome and anterior cavernous syndrome secondary to herpetic zoster ophthalmicus (HZO), despite being on oral acyclovir. Urgent treatment with intravenous acyclovir led to improvement of the orbital and ocular inflammation but had no effect on the complete ophthalmoplegia and profound visual loss. At the 9-month follow-up visit, the patient had complete unilateral ophthalmoplegia and monocular blindness due to optic atrophy. Read More

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http://dx.doi.org/10.4103/ijo.IJO_592_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213683PMC
November 2018
1 Read

Ein nicht heilender Herpes zoster ophthalmicus.

J Dtsch Dermatol Ges 2018 Oct;16(10):1274-1277

Dermatologische Abteilung Krankenhaus Hietzing, Wien.

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http://dx.doi.org/10.1111/ddg.13641_gDOI Listing
October 2018
1 Read

Isolated optic neuritis with a concurrent abnormal trigeminal nucleus on imaging: case report of a rare complication of herpes zoster ophthalmicus.

BMC Neurol 2018 Oct 4;18(1):165. Epub 2018 Oct 4.

Department of Ophthalmology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, 270 Rama VI Road, Bangkok, 10400, Thailand.

Background: Herpes zoster ophthalmicus (HZO) is an inflammation related to reactivation of the latent varicella zoster virus (VZV), involving the ophthalmic branch of the trigeminal nerve. Optic neuritis (ON), a rare ocular complication following HZO, has been reported in 1.9% of HZO-affected eyes. Read More

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https://bmcneurol.biomedcentral.com/articles/10.1186/s12883-
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http://dx.doi.org/10.1186/s12883-018-1168-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171195PMC
October 2018
4 Reads

Herpes Zoster: Epidemiological Links With Stroke and Myocardial Infarction.

J Infect Dis 2018 Sep;218(suppl_2):S102-S106

Faculty of Epidemiology and Population Health, London School of Hygiene Tropical Medicine, UK.

Routine data from electronic health records (EHRs) provide insights into links between herpes zoster (HZ) and cardiovascular complications such as stroke or myocardial infarction (MI) in different populations worldwide. Evidence from large EHR studies using both self-controlled case series and traditional cohort designs suggests that there is a transient increase in the risk of stroke after HZ, which gradually resolves over 6-12 months. In these studies, herpes zoster ophthalmicus was associated with a higher risk of stroke than HZ at other sites. Read More

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http://dx.doi.org/10.1093/infdis/jiy385DOI Listing
September 2018
6 Reads

Increased risk of neovascular age-related macular degeneration in patients with herpes zoster ophthalmicus: a retrospective cohort study.

Acta Ophthalmol 2018 Sep 14. Epub 2018 Sep 14.

Sleep Research Center, Taipei Medical University Hospital, Taipei, Taiwan.

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http://dx.doi.org/10.1111/aos.13924DOI Listing
September 2018
1 Read

Morphea «En Coup De Sabre» at the Site of Healed Herpes Zoster Ophthalmicus.

Actas Dermosifiliogr 2018 Sep 7. Epub 2018 Sep 7.

Departamento of Dermatología, Facultad de Medicina Jawaharlal Nehru (JNMC), Universidad Aligarh Muslim (AMU), Aligarh, India.

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https://linkinghub.elsevier.com/retrieve/pii/S00017310183035
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http://dx.doi.org/10.1016/j.ad.2018.03.022DOI Listing
September 2018
5 Reads

Neurological and Ophthalmological Manifestations of Varicella Zoster Virus.

J Neuroophthalmol 2018 Sep 1. Epub 2018 Sep 1.

Department of Neurological Sciences (SK, LNJ), University of Nebraska Medical Center, Omaha, Nebraska; Stanley M Truhlsen Eye Institute (SK), University of Nebraska Medical Center, Omaha, Nebraska; and Department of Neurology (JRB), Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

Background: Approximately 1 million new cases of herpes zoster (HZ) occur in the United States annually, including 10%-20% with herpes zoster ophthalmicus (HZO). Postherpetic neuralgia, a debilitating pain syndrome occurs in 30% HZ, whereas 50% HZO develop ophthalmic complications. Diplopia from cranial nerve palsy occurs in less than 30% HZO, whereas optic neuropathy is seen in less than 1% HZO. Read More

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http://dx.doi.org/10.1097/WNO.0000000000000721DOI Listing
September 2018
7 Reads

Non-healing herpes zoster ophthalmicus.

J Dtsch Dermatol Ges 2018 Oct 31;16(10):1274-1275. Epub 2018 Aug 31.

Department of Dermatology, Hietzing Hospital, Vienna, Austria.

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http://doi.wiley.com/10.1111/ddg.13641
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http://dx.doi.org/10.1111/ddg.13641DOI Listing
October 2018
5 Reads

Current Practice Patterns and Opinions on the Management of Recent-Onset or Chronic Herpes Zoster Ophthalmicus of Zoster Eye Disease Study Investigators.

Cornea 2019 Jan;38(1):13-17

Department of Ophthalmology, New York University School of Medicine, New York, NY.

Purpose: To determine practices and opinions among study investigators in the Zoster Eye Disease Study (ZEDS) regarding suppressive valacyclovir treatment for recent-onset and chronic herpes zoster ophthalmicus (HZO).

Methods: An Internet-based survey was distributed to 170 ZEDS study investigators with questions regarding treatment practices for stromal keratitis in HZO and opinions regarding the efficacy of prolonged antiviral prophylaxis.

Results: The response rate was 72. Read More

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http://dx.doi.org/10.1097/ICO.0000000000001732DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279559PMC
January 2019
16 Reads

Correlating CD4 count with mucocutaneous manifestations in HIV-positive patients: A prospective study.

Indian J Sex Transm Dis AIDS 2017 Jul-Dec;38(2):128-135

Department of Community Medicine, Government Villupuram Medical College and Hospital, Villupuram, Tamil Nadu, India.

Background: Mucocutaneous findings may be the presenting symptoms in HIV-afflicted individuals. A multitude of mucocutaneous diseases also occurs during the course of the ailment, with some conditions being classed as disease defining. They include infectious diseases and noninfective inflammatory and neoplastic dermatoses. Read More

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http://dx.doi.org/10.4103/ijstd.IJSTD_130_15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085934PMC
August 2018
7 Reads

[Herpes zoster ophthalmicus in an immunosuppressed patient].

Aten Primaria 2018 Aug 7. Epub 2018 Aug 7.

Servicio de Medicina Interna, Hospital Universitario San Agustín, Avilés, Asturias, España.

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http://dx.doi.org/10.1016/j.aprim.2018.06.005DOI Listing
August 2018
1 Read

Review for Disease of the Year: Treatment of Viral Anterior Uveitis: A Perspective.

Ocul Immunol Inflamm 2018 10;26(7):1135-1142. Epub 2018 Aug 10.

a Clinic for Vitreoretinal Diseases , Swiss Eye Institute and Berner Augenklinik am Lindenhofspital , Bern , Switzerland.

Purpose: To define a clinically tailored therapeutic strategy for the treatment of viral anterior uveitis (VAU).

Methods: A PubMed search spanning the past 5 years was conducted using the MesH-terms "viral anterior uveitis" and "therapy."

Results: The herpes simplex virus (HSV), the varicella zoster virus (VZV), and the cytomegalovirus (CMV) are the predominant pathogens in VAU. Read More

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http://dx.doi.org/10.1080/09273948.2018.1498109DOI Listing
December 2018
3 Reads

[Ophthalmic zoster: an uncommon dermatosis in infants].

Pan Afr Med J 2018 15;29:153. Epub 2018 Mar 15.

Service des Urgences Médicales Pédiatriques Hôpital d'Enfants, Rabat, Maroc.

We here report the case of a 9-month infant, born to a mother with a history of varicella in the third trimester of pregnancy but with no history of atopy, admitted to the emergency room with painful, pruritic rash in the right hemiface that had been ongoing for 4 days. During physical examination, the infant appeared to be in pain, with multiple cluster of grouped vesicles on erythematous skin in the right hemiforehead, in the right side of the nose and in the right cheek associated with edema of the upper and lower eyelids, with difficulty opening eyes and purulent conjunctival secretions. The infant was afebrile and in a good general condition. Read More

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http://dx.doi.org/10.11604/pamj.2018.29.153.13216DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057568PMC
August 2018
8 Reads

Hutchinson's sign as a predictor of ocular impairment in herpes zoster ophthalmicus.

Rev Clin Esp 2018 Jul 17. Epub 2018 Jul 17.

Servicio de Medicina Interna, Hospital Universitario de Fuenlabrada, Universidad Rey Juan Carlos, Fuenlabrada, Madrid, España.

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http://dx.doi.org/10.1016/j.rce.2018.06.007DOI Listing

Herpes zoster ophthalmicus caught in the (Tr)act!

Emerg Radiol 2018 Jul 10. Epub 2018 Jul 10.

Department of Radiology, Northport VA Medical Center, 79 Middleville Road, Northport, NY, USA.

To emphasize the utility of contrast enhanced MRI for identifying the extent of disease in herpes zoster ophthalmicus with intracranial extension to help determine proper management. We present a rare case of herpes zoster ophthalmicus (HZ/HZO) with intracranial extension and MRI demonstration of involvement of the trigeminal nerve, the trigeminal nucleus, and the spinal trigeminal nucleus and tract. Herpes zoster is caused by reactivation of varicella zoster virus. Read More

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http://dx.doi.org/10.1007/s10140-018-1622-yDOI Listing
July 2018
3 Reads

Effectiveness of real-time PCR for diagnosis and prognosis of varicella-zoster virus keratitis.

Jpn J Ophthalmol 2018 Jul 11;62(4):425-431. Epub 2018 Jun 11.

Division of Ophthalmology and Visual Science, Faculty of Medicine, Tottori University, 36-1 Nishi-cho, Yonago Tottori, 683-8504, Japan.

Purpose: To determine the efficacy of real-time PCR for the diagnosis and prognosis of varicella-zoster virus (VZV) keratitis.

Study Design: Retrospective case series.

Methods: Patients: 545 consecutive patients with keratitis were examined to quantify copy numbers of VZV DNA by real-time PCR. Read More

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http://link.springer.com/10.1007/s10384-018-0604-7
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http://dx.doi.org/10.1007/s10384-018-0604-7DOI Listing
July 2018
19 Reads

Using natural language processing for identification of herpes zoster ophthalmicus cases to support population-based study.

Clin Exp Ophthalmol 2018 Jun 19. Epub 2018 Jun 19.

Department of Research and Evaluation, Kaiser Permanente Southern California, Pasadena, California, USA.

Importance: Diagnosis codes are inadequate for accurately identifying herpes zoster (HZ) ophthalmicus (HZO). There is significant lack of population-based studies on HZO due to the high expense of manual review of medical records.

Background: To assess whether HZO can be identified from the clinical notes using natural language processing (NLP). Read More

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http://dx.doi.org/10.1111/ceo.13340DOI Listing
June 2018
7 Reads

[Herpes zoster ophthalmicus].

Aten Primaria 2018 Jun 12. Epub 2018 Jun 12.

Médico de Familia, Centro de Salud La Paz, Badajoz, España.

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http://dx.doi.org/10.1016/j.aprim.2018.04.002DOI Listing

Herpes zoster ophthalmicus.

CMAJ 2018 May;190(21):E656

Department of Ophthalmology & Visual Sciences, University of Alberta, Edmonton, Alta.

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http://www.cmaj.ca/lookup/doi/10.1503/cmaj.180063
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http://dx.doi.org/10.1503/cmaj.180063DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5973887PMC
May 2018
4 Reads

Herpes zoster ophthalmicus: acute keratitis.

Authors:
Jennifer Y Li

Curr Opin Ophthalmol 2018 Jul;29(4):328-333

University of California, Davis, UC Davis Eye Center Sacramento, California, USA.

Purpose Of Review: Herpes zoster is a common condition, and involvement of the trigeminal nerve results in herpes zoster ophthalmicus (HZO). Acute keratitis is one of the most common of these ocular complications associated with HZO. The findings associated with and the management of acute zoster keratitis will be reviewed. Read More

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http://dx.doi.org/10.1097/ICU.0000000000000491DOI Listing
July 2018
1 Read

A Pediatric Case of Relapsing-Remitting Multiple Sclerosis Onset following Varicella Zoster Ophthalmicus with Optic Neuritis.

Case Rep Pediatr 2018 26;2018:6931206. Epub 2018 Mar 26.

Department of Pediatrics, Shinshu University School of Medicine, Matsumoto, Japan.

Some epidemiological studies have implied a pathogenetic association between varicella zoster virus (VZV) and multiple sclerosis (MS); this, however, remains controversial. The present report describes a case involving an immunocompetent 10-year-old girl who developed relapsing-remitting MS following the prolonged reactivation of VZV inside the first branch of the trigeminal nerve, exhibiting herpes zoster ophthalmicus with severe optic neuritis. Symptoms related to herpes zoster ophthalmicus and MS appeared consecutively in the 10-week period after the appearance of vesicles. Read More

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http://dx.doi.org/10.1155/2018/6931206DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5892297PMC
March 2018
3 Reads

High resolution vessel wall MRI and vasculopathy related to herpes zoster ophthalmicus.

Clin Imaging 2018 Jul - Aug;50:336-339. Epub 2018 May 3.

Department of Radiology, Massachusetts General Hospital, Boston, MA, USA.

Varicella zoster virus is a common viral infection with over 50% of patients over the age of 80 years infected with the virus. Following reactivation, some patients succumb to complications of VZV reactivation with neurologic and optic pathway pathology such as VZV vasculopathy resulting in transient ischemic attacks, strokes, aneurysms, as well as optic neuritis. We show that high resolution vessel wall magnetic resonance imaging can aid in the diagnosis of this condition with circumferential wall thickening and enhancement of the infected vessels. Read More

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http://dx.doi.org/10.1016/j.clinimag.2018.05.002DOI Listing
October 2018
2 Reads

An older woman with herpes zoster ophthalmicus complicated by orbital apex syndrome.

Age Ageing 2018 Sep;47(5):760

Department of Radiology, Geneva University Hospitals, Thonex, Switzerland.

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http://dx.doi.org/10.1093/ageing/afy073DOI Listing
September 2018
3 Reads

Heightened risk of ischemic stroke after recent herpes zoster ophthalmicus.

Authors:
Charles Grose

J Med Virol 2018 Aug 10;90(8):1283-1284. Epub 2018 May 10.

Virology Laboratory, Children's Hospital, University of Iowa, Iowa City, Iowa.

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http://dx.doi.org/10.1002/jmv.25201DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013390PMC

Management of chronic complications associated with herpes zoster ophthalmicus.

Curr Opin Ophthalmol 2018 Jul;29(4):334-339

Department of Ophthalmology and Visual Sciences, University of Maryland School of Medicine, Baltimore, Maryland, USA.

Purpose Of Review: Herpes zoster ophthalmicus (HZO) has the potential to cause significant visual morbidity and functional disability in patients with recalcitrant disease, keratitis, and postherpetic neuralgia. This article will review the current methods of prevention and treatment of anterior segment-related chronic complications of HZO.

Recent Findings: HZO-related anterior segment ocular complications can range to include conjunctivitis, keratitis, and uveitis that can all be difficult to manage. Read More

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http://dx.doi.org/10.1097/ICU.0000000000000492DOI Listing

Current vaccines for the prevention of herpes zoster.

Curr Opin Ophthalmol 2018 Jul;29(4):355-359

University of Miami Miller School of Medicine/ Bascom Palmer Eye Institute.

Purpose Of Review: To summarize the recent advances in the prevention of herpes zoster. The recent Food and Drug Administration (FDA) approval of an adjuvanted subunit vaccine may have a significant impact on the prevention of herpes zoster ophthalmicus.

Recent Findings: There are currently two commercially available vaccines for the prevention of herpes zoster: a live-attenuated vaccine and a new recombinant subunit vaccine. Read More

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http://dx.doi.org/10.1097/ICU.0000000000000480DOI Listing

The Skin and the Eye - Herpes Zoster Ophthalmicus in a Healthy 18-month-old Toddler.

Folia Med (Plovdiv) 2018 Mar;60(1):170-174

Department of Ophthalmology, Faculty of Medicine, Medical University of Plovdiv, Plovdiv, Bulgaria.

Herpes zoster, caused by reactivation of varicella-zoster virus, is uncommon in infancy. Even more uncommon is herpes zoster ophthalmicus, defined as herpes zoster of the ophthalmic branch of the fifth cranial nerve. Among healthy children, primary varicella-zoster virus infection during gestation as a result of maternal varicella or the first year of life is the major risk factor for development of herpes zoster in a relatively young age. Read More

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http://dx.doi.org/10.1515/folmed-2017-0064DOI Listing
March 2018
6 Reads

Herpes Zoster Ophthalmicus With Orbital Findings Preceding Skin Rash.

Ophthalmic Plast Reconstr Surg 2018 Jul/Aug;34(4):e113-e115

Department of Ophthalmology, Medical College of Wisconsin, Milwaukee, Wisconsin, U.S.A.

The authors describe 2 patients who presented with orbital findings and later developed vesicular lesions that were positive for varicella zoster virus and consistent with Herpes Zoster ophthalmicus. One case is the first to involve dacryoadenitis and orbital myositis preceding disseminated Herpes Zoster. In the other case, a patient developed zoster orbital syndrome leading to elevated intraocular pressure, loss of vision, and afferent pupillary defect. Read More

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http://dx.doi.org/10.1097/IOP.0000000000001112DOI Listing

Treatment of herpes zoster ophthalmicus: a systematic review and Canadian cost-comparison.

Can J Ophthalmol 2018 04 10;53(2):117-123. Epub 2017 Oct 10.

Schulich School of Medicine & Dentistry, Western University, London, Ont; Ivey Eye Institute, St. Joseph's Health Care London, London, Ont.. Electronic address:

Objective: A systematic review and cost comparison were conducted to determine the optimal treatment of active herpes zoster ophthalmicus (HZO) in immunocompetent adults.

Design: A literature search of MEDLINE, EMBASE, CINAHL, Cochrane Library, BIOSIS Previews and Web of Science, ClinicalTrials.gov, International Clinical Trials Registry Platform, Networked Digital Library of Theses and Dissertations, and Canadian Health Research Collection was performed. Read More

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http://dx.doi.org/10.1016/j.jcjo.2017.08.005DOI Listing
April 2018
1 Read

Varicella-zoster virus necrotising retinitis, retinal vasculitis and panuveitis following uncomplicated chickenpox in an immunocompetent child.

BMJ Case Rep 2018 Apr 5;2018. Epub 2018 Apr 5.

Manchester Royal Eye Hospital, Manchester, UK.

A 4-year-old girl presented with acute left visual loss 4 weeks after uneventful chickenpox. She was found to have left necrotising retinitis and profound retinal vasculitis and vitritis. Aqueous humour was PCR positive for varicella-zoster virus. Read More

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http://dx.doi.org/10.1136/bcr-2017-223823DOI Listing
April 2018
3 Reads

Risk of Anterior Segment Complications Associated With the Live Herpes Zoster Vaccine: Evidence From a Health-Claim Database.

Cornea 2018 Aug;37(8):952-956

Department of Ophthalmology and Visual Sciences, The University of British Columbia, Vancouver, Canada.

Purpose: To determine the risk of developing anterior segment complications after receiving the live herpes zoster virus vaccine.

Methods: This retrospective cohort study included a random sample of 9 million patients registered in a health-claim database in the United States between 2006 and 2016. Herpes zoster-related anterior segment diseases were identified by International Classification of Diseases ninth or tenth edition codes (an event). Read More

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http://Insights.ovid.com/crossref?an=00003226-201808000-0000
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http://dx.doi.org/10.1097/ICO.0000000000001595DOI Listing
August 2018
13 Reads

Corneal Innervation and Sensation: The Eye and Beyond.

Yale J Biol Med 2018 03 28;91(1):13-21. Epub 2018 Mar 28.

Department of Ophthalmology and Visual Science, Yale School of Medicine, New Haven, CT.

The cornea is one of the most densely innervated and sensitive tissues in the body. In addition to their important sensory functions, corneal nerves induce reflex tear production, blinking, and the release of trophic factors - all of which combined help to maintain the structural and functional integrity of the surface of the eye. Consequently, damage to corneal nerves as a result of disease, surgery, or trauma can lead to diminished corneal sensitivity, epithelial defects, and possible blindness. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5872636PMC
March 2018
14 Reads

Progressive outer retinal necrosis after rituximab and cyclophosphamide therapy.

Indian J Ophthalmol 2018 04;66(4):591-593

Advanced Eye Centre, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

We report a case of progressive outer retinal necrosis (PORN) in a patient of microscopic polyangitis (MPA), being treated with immunosuppressive drugs such as cyclophosphamide and rituximab. Her aqueous tap was positive for Varicella Zoster virus and she was treated with oral and intravitreal antivirals, along with discontinuation of one of the immunosuppressive agents, i.e. Read More

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http://dx.doi.org/10.4103/ijo.IJO_811_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5892074PMC
April 2018
9 Reads
0.930 Impact Factor

Orbital Apex Syndrome Secondary to Herpes Zoster Ophthalmicus.

Turk J Ophthalmol 2018 Feb 23;48(1):42-46. Epub 2018 Feb 23.

Dokuz Eylul University Faculty of Medicine, Department of Radiology, İzmir, Turkey.

Orbital apex syndrome is a rare complication of herpes zoster ophthalmicus. A patient being followed in our clinic for herpes zoster ophthalmicus developed orbital apex syndrome in the second week of treatment. Clinical diagnosis was supported by magnetic resonance imaging. Read More

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http://dx.doi.org/10.4274/tjo.02256DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854859PMC
February 2018
11 Reads

Herpes zoster ophthalmicus evolving into headache characterised as hemicrania continua.

BMJ Case Rep 2018 Mar 23;2018. Epub 2018 Mar 23.

Department of Neurolgy, Smt BK Shah Medical Institute and Research Centre, Vadodara, India.

Postherpetic neuralgia (PHN) is the most common chronic complication of herpes zoster infection. However, a few patients may develop different types of pain after herpetic lesions. We are reporting two patients who developed postherpetic hemicrania continua (HC). Read More

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http://dx.doi.org/10.1136/bcr-2018-224235DOI Listing
March 2018
18 Reads

Small Vessel Vasculitis in Herpes Zoster-Discussion of Current Aspects of Varicella Zoster Virus Vasculopathy.

Am J Dermatopathol 2018 Aug;40(8):602-604

Department of Dermatology, Saarland University Medical Center, Homburg/Saar, Germany.

Varicella zoster virus (VZV) vasculopathy was initially described as herpes zoster ophthalmicus with contralateral hemiplegia in 1896. VZV is able to infect endothelial cells directly, leading to a thickened intima and vascular remodeling due to inflammation. Therefore, a spectrum of vasculopathies is induced, ranging from a discrete capillaritis-to-granulomatous vasculitis and obliterative angiitis. Read More

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http://dx.doi.org/10.1097/DAD.0000000000001134DOI Listing
August 2018
4 Reads

Management of herpes zoster (shingles) during pregnancy.

J Obstet Gynaecol 2018 Mar 22:1-8. Epub 2018 Mar 22.

a Medical College of Georgia , Augusta University , Augusta , GA , USA.

An infection with the varicella-zoster virus (VZV) causes both varicella and herpes zoster (HZ). Although rare, the development of HZ does occur during pregnancy. Maternal HZ does not result in increased foetal mortality, and the passage of VZV to the foetus rarely occurs. Read More

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https://www.tandfonline.com/doi/full/10.1080/01443615.2018.1
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http://dx.doi.org/10.1080/01443615.2018.1446419DOI Listing
March 2018
10 Reads

Case Series: Herpes Zoster Ophthalmicus with Acute Orbital Inflammation.

Optom Vis Sci 2018 Apr;95(4):405-410

Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea.

Significance: Herpes zoster ophthalmicus (HZO) has variable initial manifestations, and acute orbital inflammation may be the first sign without apparent zoster rash. This case series is significant for presenting diverse clinical features and treatment options of HZO with acute orbital inflammation.

Purpose: To report a case series of patients diagnosed as HZO with acute orbital inflammation including two cases with unique presentations. Read More

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http://dx.doi.org/10.1097/OPX.0000000000001204DOI Listing
April 2018
14 Reads

Herpes zoster ophthalmicus: Pre-eruption phase sine herpete.

Am J Ophthalmol Case Rep 2018 Jun 8;10:201-202. Epub 2018 Mar 8.

Department of Ophthalmology, Baylor College of Medicine, Houston, TX, United States.

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http://dx.doi.org/10.1016/j.ajoc.2018.03.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854874PMC
June 2018
1 Read

Immunopathology of Virus-Induced Anterior Uveitis.

Ocul Immunol Inflamm 2018 15;26(3):338-346. Epub 2018 Mar 15.

g Department of Viroscience , Erasmus MC , Rotterdam , The Netherlands.

Herpes simplex virus, varicella zoster virus, human cytomegalovirus, and rubella virus are the most common causes of virus-induced anterior uveitis. They can present in a variety of entities not only with typical but also overlapping clinical characteristics. These viral infections are commonly associated with ocular infiltration of T cells and B/plasma cells, and expression of cytokines and chemokines typical of a proinflammatory immune response. Read More

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http://dx.doi.org/10.1080/09273948.2018.1439069DOI Listing

ACUTE RETINAL NECROSIS AND CONTRALATERAL CUTANEOUS ERUPTION AFTER THE SHINGLES VACCINE.

Retin Cases Brief Rep 2018 Mar 8. Epub 2018 Mar 8.

Department of Ophthalmology, New York Medical College.

Purpose: To the best of our knowledge, we present a rare case report describing an occurrence of acute retinal necrosis in an otherwise healthy individual who received the shingles vaccine.

Methods: Observational case report.

Patient: A 63-year-old healthy and immunocompetent white man presented with change of vision in the left eye after blunt trauma. Read More

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http://dx.doi.org/10.1097/ICB.0000000000000729DOI Listing
March 2018
1 Read

[Cerebral infarction related to varicella zoster virus vasculopathy].

Rinsho Shinkeigaku 2018 Mar 28;58(3):182-187. Epub 2018 Mar 28.

Department of Neurology, Graduate School of Medical Sciences, Kumamoto University.

A 14-year-old girl developed transient disturbance of consciousness, dysarthria, and clumsiness of the right upper limb 4 months after herpes zoster ophthalmicus. Brain MRI showed acute cerebral infarction in the left middle cerebral artery (MCA) territory. CT angiography demonstrated mild stenosis in the top of the left internal carotid artery and the proximal side of the MCA. Read More

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http://dx.doi.org/10.5692/clinicalneurol.cn-001117DOI Listing
March 2018
1 Read

Herpes zoster ophthalmicus with associated vasculopathy causing stroke.

Dermatol Online J 2017 Jul 15;23(7). Epub 2017 Jul 15.

University Of Cincinnati, Department of Dermatology, Cincinnati, Ohio.

Varicella zoster virus (VZV) is an exclusively human, double-stranded DNA virus. Primary infection causes varicella (chickenpox); later the virus becomes dormant in the dorsal root, cranial nerve, and autonomic ganglia along the entire span of the nervous system, retaining the capacity to reactivate and cause a variety of dermal and neurological complications. Recently there has been increasing recognition, both clinically and epidemiologically, of the relationship between VZV and subsequent strokes. Read More

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July 2017
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Rapid Detection and Identification of Uveitis Pathogens by Qualitative Multiplex Real-Time PCR.

Invest Ophthalmol Vis Sci 2018 01;59(1):582-589

Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts, United States.

Purpose: Infectious uveitis is a serious sight-threatening infection commonly caused by herpesviruses and Toxoplasma gondii. Etiologic diagnosis based on the clinical evaluation is often challenging. We developed and validated a multiplex real-time PCR assay coupled with high-resolution melting (HRM) for rapid detection and identification of herpes simplex viruses 1 and 2 (HSV-1 and HSV-2), varicella-zoster virus (VZV), cytomegalovirus (CMV), and T. Read More

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http://dx.doi.org/10.1167/iovs.17-22597DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788046PMC
January 2018
3 Reads

Identification of Herpes Zoster-Associated Temporal Arteritis Among Cases of Giant Cell Arteritis.

Am J Ophthalmol 2018 03 30;187:51-60. Epub 2017 Dec 30.

Division of Neuro-Ophthalmology, Department of Ophthalmology and Visual Sciences, University of Iowa, Iowa City, Iowa.

Purpose: To examine whether herpes zoster antigen (also called varicella-zoster virus antigen) was detectable in temporal artery biopsies taken from individuals with giant cell arteritis (GCA).

Design: Retrospective comparative case series.

Methods: Sections of formalin-fixed paraffin-embedded temporal arteries were examined first by hematoxylin-eosin (H&E) staining to establish the diagnosis of GCA. Read More

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http://dx.doi.org/10.1016/j.ajo.2017.12.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866091PMC
March 2018
11 Reads

Treatment of Progressive Herpes Zoster-Induced Vasculopathy with Surgical Revascularization: Effects on Cerebral Hemodynamics.

World Neurosurg 2018 Mar 20;111:132-138. Epub 2017 Dec 20.

Department of Neurological Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA.

Background: Herpes zoster ophthalmicus (HZO) is caused by reactivation of the herpes simplex virus in the trigeminal nerve. HZO-initiated cerebral vasculopathy is well characterized; however, there are no documented cases that report the efficacy of surgical revascularization for improving cerebral hemodynamics following progressive HZO-induced vasculopathy. We present a case in which quantitative anatomic and hemodynamic imaging were performed longitudinally before and after surgical revascularization in a patient with HZO and vasculopathic changes. Read More

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http://dx.doi.org/10.1016/j.wneu.2017.12.087DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5835181PMC
March 2018
8 Reads

Herpes Zoster Optic Neuropathy.

J Neuroophthalmol 2018 Jun;38(2):179-189

Boston University School of Medicine (ARK), Boston, Massachusetts; Department of Ophthalmology (EMM, KCG), University of Cincinnati, Cincinnati Eye Institute, Cincinnati, Ohio; Neuro-Ophthalmology Service (MLM), Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania; and Department of Ophthalmology (JS, LBK), University of Alabama School of Medicine, Birmingham, Alabama.

Background: Herpes zoster optic neuropathy (HZON) is a rare manifestation of herpes zoster ophthalmicus (HZO). The aim of our study was to better characterize the clinical features, therapeutic choices, and visual outcomes in HZON.

Methods: A retrospective chart review was performed at multiple academic eye centers with the inclusion criteria of all eyes presenting with optic neuropathy within 1 month of cutaneous zoster of the ipsilateral trigeminal dermatome. Read More

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http://dx.doi.org/10.1097/WNO.0000000000000607DOI Listing
June 2018
4 Reads

Increased risk of dementia following herpes zoster ophthalmicus.

PLoS One 2017 22;12(11):e0188490. Epub 2017 Nov 22.

School of Health Care Administration, Taipei Medical University, Taipei, Taiwan.

This retrospective cohort study aimed to examine the relationship between herpes zoster ophthalmicus (HZO) and the subsequent risk of dementia using a population-based database. We retrieved the study sample from the Taiwan Longitudinal Health Insurance Database 2005. The study group included 846 patients with HZO, and the comparison group included 2538 patients without HZO. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0188490PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5699837PMC
December 2017
3 Reads

[Orbital apex syndrome secondary to herpes zoster ophthalmicus].

J Fr Ophtalmol 2017 Dec 25;40(10):e385-e388. Epub 2017 Oct 25.

Service d'ophtalmologie, hôpital Bretonneau, centre hospitalier universitaire de Tours, 2, boulevard Tonnellé, 37044 Tours cedex 9, France; Faculté de médecine de Tours, 10, boulevard Tonnellé, BP 3223, 37032 Tours cedex 1, France.

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http://dx.doi.org/10.1016/j.jfo.2016.09.025DOI Listing
December 2017
1 Read