17,889 results match your criteria Herpes Zoster

Cost-effectiveness of varicella and herpes zoster vaccination in Sweden: An economic evaluation using a dynamic transmission model.

PLoS One 2021 13;16(5):e0251644. Epub 2021 May 13.

Department of Public Health Analysis and Data Management, Public Health Agency of Sweden, Solna, Sweden.

Objectives: Comprehensive cost-effectiveness analyses of introducing varicella and/or herpes zoster vaccination in the Swedish national vaccination programme.

Design: Cost-effectiveness analyses based on epidemiological results from a specifically developed transmission model.

Setting: National vaccination programme in Sweden, over an 85- or 20-year time horizon depending on the vaccination strategy. Read More

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Surveillance of Vaccination Coverage Among Adult Populations -United States, 2018.

MMWR Surveill Summ 2021 May 14;70(3):1-26. Epub 2021 May 14.

Problem/condition: Adults are at risk for illness, hospitalization, disability and, in some cases, death from vaccine-preventable diseases, particularly influenza and pneumococcal disease. CDC recommends vaccinations for adults on the basis of age, health conditions, prior vaccinations, and other considerations. Updated vaccination recommendations from CDC are published annually in the U. Read More

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P2X7 receptor antagonist BBG inhibits endoplasmic reticulum stress and pyroptosis to alleviate postherpetic neuralgia.

Mol Cell Biochem 2021 May 12. Epub 2021 May 12.

Department of Dermatology, The First Affiliated Hospital of USTC, 17 Lujiang Road, Hefei, 230001, Anhui Province, China.

Postherpetic neuralgia (PHN) is the most common complication of acute herpes zoster. The treatment of PHN remains a challenge for clinical pain management. The present study investigated the P2X7 receptor antagonist brilliant blue G (BBG) whether inhibits endoplasmic reticulum stress and pyroptosis (a necrotic form of cell death) and alleviates PHN. Read More

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Promoting Healthy Ageing in South Africa Through Vaccination of the Elderly.

Front Public Health 2021 26;9:635266. Epub 2021 Apr 26.

South African Vaccination and Immunisation Centre, Sefako Makgatho Health Sciences University, Pretoria, South Africa.

The World Health Organization estimates that globally, the proportion of people aged ≥60 years will more than double by the year 2050, with the majority of elderly people living in low- and middle-income countries such as South Africa. Population ageing is an impending public health concern, potentially negatively impacting on South Africa's economy and health system if the government does not adequately prepare for this change. Globally, many potential solutions to ensure healthy ageing are being discussed and implemented, including adopting a "life-course" approach to vaccination which includes vaccination of the elderly, since they are at considerable risk of severe morbidity and mortality from vaccine-preventable diseases. Read More

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Erosive pustular dermatosis after herpes zoster.

Health Sci Rep 2021 Jun 5;4(2):e277. Epub 2021 May 5.

Department of Pathology, Medical Faculty Maltepe University Istanbul Turkey.

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Bilateral Limbal Stem Cell Alterations in Patients With Unilateral Herpes Simplex Keratitis and Herpes Zoster Ophthalmicus as Shown by In Vivo Confocal Microscopy.

Invest Ophthalmol Vis Sci 2021 May;62(6):12

Eye Hospital, The First Affiliated Hospital of Harbin Medical University, No.143, Yiman Street, Harbin City, Nangang District, Heilongjiang Province, China.

Purpose: The purpose of this study was to investigate the limbal changes in the palisades of Vogt (POV) in patients with herpes simplex keratitis (HSK) and herpes zoster ophthalmicus (HZO) with the application of in vivo confocal microscopy (IVCM).

Methods: We enrolled 35 eyes of 35 consecutive patients with HSK and 4 patients with HZO in this observational study. Thirty-five participants were also recruited from a healthy population as the control group. Read More

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Adult preventive vaccines with other synergistic lifestyle options: is it time to add these ancillary benefits to the overall AS management checklist?

Mark A Moyad

World J Urol 2021 May 7. Epub 2021 May 7.

Department of Urology, University of Michigan Medical Center, Ann Arbor, MI, 48109-5330, USA.

Purpose: To review the potential ancillary cardiovascular and other health impacts of compliance with general adult vaccination series in the prostate cancer active surveillance (AS) population. No previous review has been published in regard to this specific topic.

Methods: Literature review of PubMed data up to December 2020 RESULTS: Compliance rates for adult vaccination are in the approximate anemic range of 25-50% with occasional higher rates of specific vaccines in the elderly population including annual influenza and pneumococcal prevention. Read More

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Uncommon presentation and complications of herpes zoster infection involving the cervical, vagus and accessory nerves which caused a delay in diagnosis and treatment.

BMJ Case Rep 2021 May 7;14(5). Epub 2021 May 7.

Department of Community Health and Family Medicine, University of Florida Physicians Family Practice Medical Group, Gainesville, Florida, USA

A 70-year-old man with a history of invasive anal squamous cell carcinoma treated with excision and chemoradiation presented to the emergency department with right-sided neck pain and submandibular lymphadenopathy. CT imaging of the head and neck was unrevealing. The patient eventually developed cranial nerves X and XI dysfunction, manifesting as severe vocal cord paralysis (dysphonia), dysphagia, asymmetric palate elevation/deviation and trapezius muscle atrophy, in addition to scalene muscle atrophy. Read More

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Validation of Coding Algorithms for the Identification of Herpes Zoster among Children.

Pharmacoepidemiol Drug Saf 2021 May 7. Epub 2021 May 7.

Department of Medicine, Division of Rheumatology, Perelman School of Medicine at the University of Pennsylvania.

Purpose: To examine the validity of International Classification of Diseases, 10th Revision, (ICD-10) code-based algorithms for herpes zoster (HZ) in the electronic medical record (EMR) of a large, integrated pediatric healthcare network and to examine baseline demographics and chronic comorbidities associated with HZ in a representative pediatric population.

Methods: We reviewed the electronic charts of all patients with a single ICD-10 for HZ (B02.xx) as their primary or secondary diagnosis in the EMR of the Children's Hospital of Philadelphia (CHOP) healthcare network from January 2010 - March 2019. Read More

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Burden of Herpes Zoster in Adult Patients with Underlying Conditions: Analysis of German Claims Data, 2007-2018.

Dermatol Ther (Heidelb) 2021 May 6. Epub 2021 May 6.

Department for Health Economics and Health Care Management, Bielefeld University, Universitätsstrasse 25, 33615, Bielefeld, Germany.

Introduction: Several chronic underlying conditions (UCs) are known to be risk factors for developing herpes zoster (HZ) and to increase the severity of HZ and its risk of recurrence. The aim of this study was to investigate the incidence and recurrence of HZ in adult patients with one or multiple UCs.

Methods: A retrospective cohort study based on claims data representing 13% of the statutory health insurance population from 2007 to 2018 in Germany was performed. Read More

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Segmental Zoster Paresis of Lower Thoracic Segment Presenting as Pseudohernia-A Report of Three Cases.

Indian Dermatol Online J 2021 Mar-Apr;12(2):324-326. Epub 2021 Feb 22.

Department of Dermatology, Venereology and Leprosy, JSS Medical College, JSS Academy of Higher Education and Research, Mysuru, Karnataka, India.

Segmental zoster paresis is characterized by focal motor weakness affecting the myotome corresponding to the dermatomal distribution of the rash. Clinically, it presents as pseudohernia when it involves abdominal wall muscles. We report three cases of segmental zoster paresis presenting as pseudohernia of abdominal wall. Read More

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February 2021

Avoidable Acute Care Use for Vaccine-Preventable Illnesses among Medicaid Beneficiaries with Lupus.

Arthritis Care Res (Hoboken) 2021 May 4. Epub 2021 May 4.

Division of Rheumatology, Inflammation and Immunity, Department of Medicine, Brigham and Women's Hospital, Boston, MA.

Objective: Nearly 25% of SLE patients are hospitalized yearly, often for outcomes that may have been avoided if patients had received sustained outpatient care. We examined acute care use for vaccine-preventable illnesses to determine sociodemographic contributors and modifiable predictors.

Methods: Using U. Read More

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Molecular Detection of Human Herpes Viruses in Suspected Measles Serum Samples from Senegal, 2014 to 2017.

Am J Trop Med Hyg 2021 May 3. Epub 2021 May 3.

1Institut Pasteur de Dakar, Unité de Virologie Médicale, Dakar, Sénégal.

Herpesviruses are known to cause a diversity of clinical syndromes, ranging from minor cutaneous lesions to life-threatening illnesses, especially in immunocompromised hosts. Here, we investigate retrospectively the contribution of five human herpesviruses, including herpes simplex virus Cytomegalovirus (CMV), the Epstein-Barr virus (EBV), human herpesvirus 6, and varicella zoster virus (VZV) in serum samples collected from measles suspected patients with at least fever and rash. Sera specimens were first tested for serological evidence of measles and rubella virus infection by ELISA, and DNA extracted from an aliquot of each clinical specimen for molecular detection of human herpes viruses by RT-qPCR. Read More

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Vessel wall MR imaging of central nervous system vasculitis: a systematic review.

Neuroradiology 2021 May 3. Epub 2021 May 3.

Department of Radiology, Hospital of the University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA, 19104, USA.

Purpose: Beyond vessel wall enhancement, little is understood about vessel wall MR imaging (VW-MRI) features of vasculitis affecting the central nervous system (CNS). We reviewed vessel wall MR imaging patterns of inflammatory versus infectious vasculitis and also compared imaging patterns for intracranial versus extracranial arteries of the head and neck.

Methods: Studies reporting vasculitis of the CNS/head and neck and included MR imaging descriptions of vessel wall features were identified by searching PubMed, Scopus, Cochrane, Web of Science, and EMBASE up to June 10, 2020. Read More

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reactivation after SARS-Cov2 BNT162b2 mRNA vaccination: Report of five cases.

JAAD Case Rep 2021 Apr 24. Epub 2021 Apr 24.

Department of Dermatology. Instituto de Investigación Sanitaria la Princesa (IIS-IP). Hospital Universitario de La Princesa.

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A Case of Herpes Zoster Granulomatous Dermatitis: Report of Wolf's Isotopic Response.

Ann Dermatol 2021 Apr 8;33(2):186-189. Epub 2021 Mar 8.

Department of Dermatology, Hallym University Sacred Heart Hospital, Anyang, Korea.

Wolf's isotopic response refers to the occurrence of a novel skin disease at the site of a preceding treated or untreated skin disease. Although the most common preceding skin disease was found to be herpes zoster (HZ), HZ-related dermatological phenomena are not well known in the literature. We report a case of HZ granulomatous dermatitis in a 77-year-old female with a previous history of hypertension, diabetes mellitus, chronic kidney disease, and HZ. Read More

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Diagnosis of cytomegalovirus corneal endotheliitis using surgically removed Descemet's membrane and endothelium despite negative results with aqueous humor PCR: a case report.

BMC Ophthalmol 2021 May 1;21(1):194. Epub 2021 May 1.

Department of Ophthalmology, University of Tokyo Graduate School of Medicine, 7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan.

Background: Cytomegalovirus (CMV) has been known to cause unilateral corneal endotheliitis with keratic precipitates and localized corneal edema, iridocyclitis, and secondary glaucoma. CMV endotheliitis is diagnosed based on clinical manifestations and viral examination using qualitative polymerase chain reaction (PCR) of the aqueous humor.

Case Presentation: An 80-year-old woman was referred to our department for bullous keratopathy. Read More

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Traditional uses, phytochemistry, pharmacology and toxicology of the genus Gynura (Compositae): A comprehensive review.

J Ethnopharmacol 2021 Apr 28:114145. Epub 2021 Apr 28.

Institute of Botany, Jiangsu Province and Chinese Academy of Sciences, Nanjing, 210014, China; Co-Innovation Center for Sustainable Forestry in Southern China, Forestry College, Nanjing Forestry University, Nanjing, 210037, China.

Ethnopharmacological Relevance: Gynura cass., belonging to the tribe Senecoineae of the family Compositae, contains more than 40 accepted species as annual or perennial herbs, mainly distributed in Asia, Africa and Australia. Among them, 11 species are distributed in China. Read More

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Evidence Map of Cupping Therapy.

J Clin Med 2021 Apr 17;10(8). Epub 2021 Apr 17.

Clinical Research Division, Korea Institute of Oriental Medicine, Daejeon 34054, Korea.

This study aimed to describe and assess the current evidence in systematic reviews on cupping therapy for various conditions. We searched PubMed, EMBASE, Cochrane Database of Systematic Reviews, China National Knowledge Infrastructure, and six Korean databases for systematic reviews of trials on cupping treatments for any condition published prior to March 2021. We used a bubble plot to graphically display the clinical topics, the number of articles, the number of participants in the total population, confidence, and effectiveness. Read More

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Herpes Zoster in an Immunocompetent Child without a History of Varicella.

Pediatr Rep 2021 Apr 1;13(2):162-167. Epub 2021 Apr 1.

Department of Pediatrics, Chung Shan Medical University Hospital, Taichung City 402, Taiwan.

Herpes zoster is a relatively rare infectious disease in the pediatric population, as compared with adults, which is due to the reactivation of latent Varicella-Zoster virus. We report a 7-year-old child without any history of varicella, who first experienced skin pain and later presented skin lesions in dermatomal distribution. Finally, the patient was diagnosed with herpes zoster. Read More

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Humoral Immunity to Varicella Zoster Virus in Patients with Systemic Lupus Erythematosus and Rheumatoid Arthritis Compared to Healthy Controls.

Vaccines (Basel) 2021 Apr 1;9(4). Epub 2021 Apr 1.

Rheumatology Unit, Clinic for Endocrinology, Nephrology and Rheumatology, Department of Internal Medicine, Neurology and Dermatology, University of Leipzig, Liebigstr. 20, 04103 Leipzig, Germany.

Background: The prevalence of herpes zoster (HZ) is high in patients with rheumatic diseases. Systemic lupus erythematosus (SLE) doubles the risk for developing HZ. However, little is known about natural humoral immunity against varicella zoster virus (VZV) in patients with SLE. Read More

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A rare cause of chronic wounds - trigeminal trophic syndrome due to Wallenberg syndrome.

Clin Exp Dermatol 2021 Apr 29. Epub 2021 Apr 29.

Department of Radiology, Ruhr-University Bochum, Bochum, Germany.

Rashid and Khachemoune previously published a comprehensive review article on trigeminal trophic syndrome (TTS) that represents a rare neurotrophic ulceration in the trigeminal area occurring as a complication of alcohol injections into the Gasserian ganglion for trigeminal neuralgia therapy or other conditions, including neoplasms, syringobulbia, and infections (herpes zoster, leprosy, lues etc.). We here report a female patient with progressive TTS due to Wallenberg syndrome. Read More

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Herpes zoster emergence following mRNA COVID-19 vaccine.

J Med Virol 2021 Apr 29. Epub 2021 Apr 29.

Dermatology Department, American University of Beirut Medical Center, Beirut, Lebanon.

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Upadacitinib in Patients with Psoriatic Arthritis and Inadequate Response to Biologics: 56-Week Data from the Randomized Controlled Phase 3 SELECT-PsA 2 Study.

Rheumatol Ther 2021 Apr 28. Epub 2021 Apr 28.

Rheumatology, Royal National Hospital for Rheumatic Diseases, Royal United Hospitals Foundation Trust, Bath, UK.

Introduction: Upadacitinib is a Janus kinase inhibitor under investigation in patients with psoriatic arthritis (PsA). This study assessed the 56-week efficacy and safety of upadacitinib in patients with PsA and an inadequate response or intolerance to biologic therapy.

Methods: In the phase 3 SELECT-PsA 2 study, patients were randomized to 56 weeks of blinded treatment with oral upadacitinib 15 or 30 mg once daily, or placebo switched to upadacitinib 15 or 30 mg once daily at week 24. Read More

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Tofacitinib for the treatment of ankylosing spondylitis: a phase III, randomised, double-blind, placebo-controlled study.

Ann Rheum Dis 2021 Apr 27. Epub 2021 Apr 27.

Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands.

Objective: To assess the efficacy/safety of tofacitinib in adult patients with active ankylosing spondylitis (AS).

Methods: This phase III, randomised, double-blind, placebo-controlled study enrolled patients aged ≥18 years diagnosed with active AS, meeting the modified New York criteria, with centrally read radiographs, and an inadequate response or intolerance to ≥2 non-steroidal anti-inflammatory drugs. Patients were randomised 1:1 to receive tofacitinib 5 mg two times per day or placebo for 16 weeks. Read More

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Severe infection including disseminated herpes zoster triggered by subclinical Cushing's disease: a case report.

BMC Endocr Disord 2021 Apr 27;21(1):84. Epub 2021 Apr 27.

Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine, Graduate School of Medicine, Hokkaido University, Sapporo, Japan.

Background: Subclinical Cushing's disease (SCD) is defined by corticotroph adenoma-induced mild hypercortisolism without typical physical features of Cushing's disease. Infection is an important complication associated with mortality in Cushing's disease, while no reports on infection in SCD are available. To make clinicians aware of the risk of infection in SCD, we report a case of SCD with disseminated herpes zoster (DHZ) with the mortal outcome. Read More

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Ein sonnenliebendes Varizella-Zoster-Virus.

MMW Fortschr Med 2021 04;163(8):28

Facharzt für Innere Medizin, München, Deutschland.

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Preferences for herpes zoster vaccination among adults aged 50 years and older in the United States: results from a discrete choice experiment.

Expert Rev Vaccines 2021 Apr 27. Epub 2021 Apr 27.

RTI Health Solutions, Research Triangle Park, NC, United States.

BackgroundMost adults, and disproportionately fewer African-Americans, have not received herpes zoster (HZ) vaccination despite current recommendations. This study (GSK study identifiers: 208677/HO-17-18066) assessed HZ vaccination preferences among adults aged ≥ 50 years.Research design and methodsIn this discrete choice experiment, respondents chose among a "no vaccine" option and two HZ vaccine profiles, characterized by seven attributes, in a series of choice questions. Read More

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The Risk of Infections Associated With JAK Inhibitors in Rheumatoid Arthritis: A Systematic Review and Network Meta-analysis.

J Clin Rheumatol 2021 Apr 24. Epub 2021 Apr 24.

From the Faculty of Pharmacy, University of Coimbra UFC-Coimbra Regional Pharmacovigilance Unit, CHAD-Centre for Health Technology Assessment and Drug Research, AIBILI-Association for Innovation and Biomedical Research on Light and Image, Coimbra, Portugal.

Background/objective: The Janus kinases (JAKs) are cytoplasmic tyrosine kinases associated with membrane cytokine receptors that mediate signaling of multiple cytokines and growth factors, contributing to the pathogenesis of multiple autoimmune disorders. The JAK inhibitors are a new class of targeted therapies with proven efficacy in treating rheumatoid arthritis but are associated with an increased risk of infections. This study is aimed at comparing the relative safety of the different JAK inhibitors with regard to the risk of serious infections in patients with rheumatoid arthritis. Read More

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Ti.: "High" vagus nerve lesions in varicella Zoster infection.

eNeurologicalSci 2021 Jun 3;23:100337. Epub 2021 Apr 3.

Rudolfinerhaus Privatklinik, Billrothstraße 78, A-1190 Vienna, Vienna and Dept. Dermatology, Krankenhaus Hietzing, Billrothstraße 78, A 1130 Vienna, Austria.

"High" vagus nerve lesions are rare and refer to the region of the nerve from the jugular foramen through the branching of the auricular (Arnold's branch) and the pharyngeal branch. Rapid onset of vagus nerve palsy is observed predominantly in trauma, and rarely in inflammation. An insidious onset points to a neoplastic cause. Read More

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