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Colorectal Dis 2019 Apr 24. Epub 2019 Apr 24.

Royal Devon & Exeter Foundation Trust, Barrack Road, Exeter, Devon, EX2 5DW.

Aim: A variety of tissue flaps have been described for the closure of perineal wounds following abdominoperineal excision of the rectum (APE) or exenteration for locally advanced/ recurrent rectal cancer and salvage surgery for anal cancer. The aim of this study was to demonstrate the utility of the bilateral pedicled gracilis muscle flaps (BPGMF) as a reconstruction option in these patients. This is of particular benefit when using a laparoscopic approach for the abdominal component of the operation, avoiding disruption of the abdominal wall and risk of herniation with other reconstruction options e. Read More

Cochrane Database Syst Rev 2019 Apr 24;4:CD009487. Epub 2019 Apr 24.

Department of Surgery, University Medical Centre Mannheim, University of Heidelberg, Theodor-Kutzer-Ufer 1-3, Mannheim, Baden-Württemberg, Germany, 68167.

Background: A parastomal hernia is defined as an incisional hernia related to a stoma, and belongs to the most common stoma-related complications. Many factors, which are considered to influence the incidence of parastomal herniation, have been investigated. However, it remains unclear whether the enterostomy should be placed through, or lateral to the rectus abdominis muscle, in order to prevent parastomal herniation and other important stoma complications. Read More

Cureus 2019 Feb 13;11(2):e4066. Epub 2019 Feb 13.

Gastroenterology and Hepatology, Saint Barnabas Hospital, Bronx, USA.

Hepatic herniation through an abdominal incisional hernia is a rare phenomenon that has been seldom reported in the medical literature. When present, this may cause patients significant distress and is associated with complications such as hepatic encephalopathy and Budd-Chiari syndrome. Most cases can be managed conservatively through observation, but many cases require surgical intervention to preserve hepatic function. Read More

BMJ Case Rep 2019 Apr 23;12(4). Epub 2019 Apr 23.

The Cambridge Colorectal Unit, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.

Small bowel obstruction (SBO) is common surgical presenting problem, accounting for roughly 15 000 laparotomies per year in the UK. However, SBO post laparoscopic transabdominal preperitoneal (TAPP) inguinal hernia repair is uncommon with an estimated incidence of 0.2%-0. Read More

BMC Surg 2019 Apr 24;19(1):40. Epub 2019 Apr 24.

Department of Surgery, Hospital del Mar, Universitat Autònoma de Barcelona, Passeig Marítim 25-29, 08003, Barcelona, Spain.

Background: Postoperative adhesions represent 75% of all acute small bowel obstructions. Although open surgery is considered the standard approach for adhesiolysis, laparoscopic approach is gaining popularity.

Methods: A retrospective study with data from a prospectively maintained data base of all patients undergoing surgical treatment for adhesive small bowel obstruction (ASBO) from January 2007 to May 2016 was conducted. Read More

Eur J Pediatr Surg 2019 Apr 23. Epub 2019 Apr 23.

Department of Pediatric Surgery, Hannover Medical School, Hannover, Germany.

Introduction:  In the last three decades, minimally invasive surgery (MIS) has been widely used in pediatric surgery. Meta-analyses (MAs) showed that studies comparing minimally invasive with the corresponding open operations are available only for selected procedures. We evaluated all available MAs comparing MIS with the corresponding open procedure in pediatric surgery. Read More

J Plast Surg Hand Surg 2019 Apr 23:1-6. Epub 2019 Apr 23.

a Division of Plastic and Reconstructive Surgery , University of Wisconsin School of Medicine and Public Health , Madison , WI , USA.

The frequency of donor-site complications following abdominal free-flap breast reconstruction remains controversial. Consensus on strategies to minimize morbidity is underdeveloped. An online survey was distributed to surgeons practicing free-flap breast reconstruction worldwide. Read More

J Invest Surg 2019 Apr 23:1-7. Epub 2019 Apr 23.

e Division of Human Genetics , Centre for Biomedical Research Faculty of Medicine Diponegoro University (FMDU) , Semarang , Indonesia.

Background: Complete androgen insensitivity syndrome (CAIS) is a congenital condition caused by genetic defects in the androgen receptor (AR) gene located on the X chromosome, which lead to a phenotypical female individual with a 46, XY karyotype. Early diagnosis of CAIS is essential for proper clinical management, allows assessment of familial risk and contributes to healthcare decisions. However, diagnosis of CAIS can be overlooked in girls with inguinal hernia, resulting in inappropriate management. Read More

J Gastrointest Surg 2019 Apr 22. Epub 2019 Apr 22.

Discipline of Surgery Flinders University, Flinders Medical Centre, Bedford Park, South Australia, 5042, Australia.

Background: The laparoscopic approach is the preferred method for repair of large hiatus hernias but can be technically challenging. Training surgeons need experience as the primary operator to gain competency in this operation. However, learning the procedure should not compromise the functional long-term outcome for patients. Read More

World J Surg 2019 Apr 22. Epub 2019 Apr 22.

Department of Surgical, Oncological and Oral Sciences, University of Palermo, Policlinico P. Giaccone. Via Liborio Giuffré 5, 90127, Palermo, Italy.

Background: Hernias severely impact patient quality of life (QoL), and 80% of patients need surgical operation. The primary outcome of the study is to assess improvements in balance, posture and deambulation after abdominal hernia repair. Moreover, the study investigated the improvement in the postoperative QoL. Read More

World J Surg 2019 Apr 22. Epub 2019 Apr 22.

Department of Surgery, Radboud University Medical Center, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands.

Background: For both gallbladder removal and inguinal hernia repair, it is important to include patients' perspective in the decision-making process, as watchful waiting is an accepted alternative in selected patients. The aim of this study was to evaluate operation rates before and after implementation of decision aids (DAs) and to assess patient compliance with the use of DAs.

Methods: A single-centered retrospective study was performed, including all patients ≥18 years referred to the surgical outpatient clinic with symptomatic gallstones or an inguinal hernia between January 2014 and December 2017. Read More

Cold Spring Harb Mol Case Stud 2019 Apr 22. Epub 2019 Apr 22.

Columbia University;

Two siblings, one male and one female, ages 6 and 13 years old have similar clinical features of global developmental delay, multiple congenital anomalies affecting the cardiac, genitourinary, and skeletal systems, and abnormal eye movements. Whole genome sequencing revealed a homozygous splice variant (NM_014462.3:c. Read More

Surg Obes Relat Dis 2019 Feb 3. Epub 2019 Feb 3.

Postgraduate Program in Medicine: Surgical Sciences, Federal University of Rio Grande do Sul, 2400 Ramiro Barcelos Street, Porto Alegre, RS, Brazil.

Background: Gastroesophageal reflux disease (GERD) impacts choice and outcomes of bariatric surgery. However, GERD diagnosis based solely on symptoms yields inaccurate results.

Objective: To determine the factors associated with a positive 24h pH-monitoring (pH-test) or esophagitis in patients with severe obesity seeking bariatric surgery. Read More

J Pediatr Urol 2019 Feb 23. Epub 2019 Feb 23.

The University of North Carolina at Chapel Hill, Department of Urology, USA.

Background: Emerging research on surgeons and the opioid epidemic have focused on the adult population. Consequently, little is known regarding opioid-prescribing practices in the pediatric population. The goal of this study is to examine postoperative opioid-prescribing and consumption patterns, as well as storage and disposal trends for specific pediatric urologic procedures. Read More

Nihon Hinyokika Gakkai Zasshi 2018 ;109(2):96-101

Department of Urology, Japanese Red Cross Nagoya First Hospital.

(Objective) A rise of intra-abdominal pressure may exacerbate pelvic organ prolapse (POP) as well as abdominal hernias. This paper aims to assess the possible risk factors of an abdominal mass and ascites as comorbidities of POP. (Methods) We retrospectively reviewed the medical charts of 2,748 POP patients between 2010 and 2016 and extracted eight cases (0. Read More

J Surg Res 2019 Apr 19;241:57-62. Epub 2019 Apr 19.

Cohen Children's Medical Center, Northwell Health System, Division of Pediatric Surgery, New York, New York; Zucker School of Medicine at Hofstra/Northwell Health System, Department of Surgery, Manhasset, New York.

Introduction: Nonmedical opioid use is a major public health problem. There is little standardization in opioid-prescribing practices for pediatric ambulatory surgery, which can result in patients being prescribed large quantities of opioids. We have evaluated the variability in postoperative pain medication given to pediatric patients following routine ambulatory pediatric surgical procedures. Read More

Ann Surg 2019 Apr 17. Epub 2019 Apr 17.

Department of Surgery, University of Michigan, Ann Arbor, MI.

J Laparoendosc Adv Surg Tech A 2019 Apr 20. Epub 2019 Apr 20.

Department of Pediatric Surgery, Fujian Provincial Maternity and Children's Hospital, Fuzhou, P.R. China.

The purpose of this study was to summarize the clinical experience of the laparoscopic percutaneous extraperitoneal closure of the internal ring using an epidural needle for the treatment of inguinal hernias. There were 1,142 children with an isolated inguinal hernia who participated in this study from January 2013 to May 2018. An epidural needle was used to treat the indirect inguinal hernia with laparoscopic assistance. Read More

J Int Med Res 2019 Apr 21:300060519844401. Epub 2019 Apr 21.

Wuhan Children's Hospital, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, China.

Objective: We aimed to investigate the role of the intestinal neurotransmitters vasoactive intestinal peptide (VIP) and substance P (SP) at different time points in infants with acute intussusception.

Methods: Thirty patients who were diagnosed with acute intussusception were enrolled in the study and classified as the experimental group. Another 30 patients with an indirect inguinal hernia who had no intestinal injury were included as the control group. Read More

Hernia 2019 Apr 20. Epub 2019 Apr 20.

Third Department of Surgery, Attikon University Hospital, National and Kapodistrian University of Athens, Athens, Greece.

Purpose: Paraduodenal hernias (PDH), also called mesocolic hernias, account for up to 53% of all internal hernias, but they cause only 0.2-0.9% of all cases of intestinal obstruction. Read More

Hernia 2019 Apr 20. Epub 2019 Apr 20.

Division of Gastrointestinal Surgery, Department of Surgery, University of Pennsylvania, Philadelphia, PA, 19104, USA.

Purpose: Body mass index (BMI) ≥ 35 kg/m is a known independent risk factor for complications following open ventral hernia repair (VHR). We sought to examine the relationship between BMI and minimally invasive VHR.

Methods: The ACS-NSQIP database was queried for all patients age ≥ 18 years undergoing minimally invasive VHR (2005-2015). Read More

J Pain 2019 Apr 18. Epub 2019 Apr 18.

Division of Anaesthesia, University of Cambridge, Cambridge, United Kingdom. Electronic address:

Cutaneous mechanical hyperalgesia can be induced in healthy volunteers in early-phase analgesic studies to model central sensitization, a key mechanism of persistent pain. However, such hyperalgesia is short-lived (a matter of hours), and is used only for assessing only single drug doses. In contrast, post-surgical peri-incisional hyperalgesia may be more persistent, and hence be a more useful model for the assessment of the efficacy of new analgesics. Read More

Acta Biomater 2019 Apr 17. Epub 2019 Apr 17.

Charles Perkins Centre, University of Sydney, NSW 2006, Australia; School of Life and Environmental Sciences, University of Sydney, NSW 2006, Australia; Bosch Institute, University of Sydney, NSW 2006, Australia. Electronic address:

Electrospun yarns offer substantial opportunities for the fabrication of elastic scaffolds for flexible tissue engineering applications. Currently available yarns are predominantly made of synthetic elastic materials. Thus scaffolds made from these yarns typically lack cell signaling cues. Read More

Hernia 2019 Apr 19. Epub 2019 Apr 19.

Division of Abdominal Wall Surgery, Department of General Surgery, Hospital Alemán of Buenos Aires, Av. Pueyrredón 1640, AAT1118C, Buenos Aires, Argentina.

Purpose: Laparoscopic inguinal hernia repair (LIHR) has demonstrated multiple benefits. However, long-term results regarding recurrence and quality of life (QoL) are still on debate. We aimed to analyze postoperative outcomes with long-term follow-up after LIHR. Read More

Hernia 2019 Apr 19. Epub 2019 Apr 19.

Minimally Invasive Paediatric Surgery Centre, Room 1105, 11/F, Nathan Road, Mong Kok, Kowloon, Hong Kong.

Background: Open herniotomy has been the gold standard of pediatric hernia treatment with the advantages of simplicity in surgical technique, fast post operative recovery, and minimal recurrence rate, but its inability to prevent hernia development from a contralateral patent processus vaginalis (PPV) after a unilateral herniotomy is its major drawback. By contrast, laparoscopic hernia repair has the advantage of contralateral internal ring inspection, and, therefore, has become popular in recent years, although open herniotomy is still the favorable surgical technique among many surgeons. A simple and reliable tool to detect contralateral PPV will be valuable to surgeons who practice conventional open hernia surgery on children, although ultrasound has been applied for this purpose, but there is no long-term data to support such application. Read More

Int J Surg Case Rep 2019 Apr 5;58:37-40. Epub 2019 Apr 5.

Radiological Department, Klatovy Hospital, Plzeňská 929, 339 01, Klatovy II, Czech Republic.

Introduction: Shortly after an operation infection, intraabdominal abscess, seroma, haemorrhage or development of paralytic ileus may occur. Postoperative adhesions, nonspecific abdominal pain without signs of obstruction, incisional hernia and appendicitis or mucocele in appendiceal stump present common late complications. We present a unique case of a late complication after appendectomy. Read More

Insights Imaging 2019 Apr 18;10(1):47. Epub 2019 Apr 18.

Department of Radiology - Musculoskeletal Imaging Unit, Cliniques universitaires Saint-Luc - Institut de Recherche Expérimentale et Clinique (IREC), Université Catholique de Louvain, Avenue Hippocrate 10, 1200, Brussels, Belgium.

The fascial system is a continuum of connective tissues present everywhere throughout the body that can be locally involved in a large variety of disorders. These disorders include traumatic disorders (Morel-Lavallée lesion, myo-aponeurotic injuries, and muscle hernia), septic diseases (necrotizing and non-necrotizing cellulitis and fasciitis), and neoplastic diseases (superficial fibromatosis, desmoid tumors, and sarcomas). The current pictorial review aims to focus on these localized disorders involving the fasciae of the musculoskeletal system and their appearance at MRI. Read More

Indian J Urol 2019 Apr-Jun;35(2):121-128

Department of Urology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.

Introduction: We present the short-term voiding patterns and functional and urodynamic outcomes of W-shaped ileal orthotopic neobladder (ONB) following radical cystectomy (RC).

Materials And Methods: Forty-one patients who underwent RC and W-shaped ONB creation between July 2015 and January 2018 were enrolled. Data were analyzed in terms of voiding patterns, urodynamic findings, and functional outcomes at 6 months after surgery. Read More

J Am Coll Surg 2019 Apr 15. Epub 2019 Apr 15.

Department of Plastic Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX.

Background: Lateral abdominal wall (LAW) myofascial defects are a challenging reconstructive problem, and no consensus exists on their surgical management. We hypothesized that mesh repairs anchored to the non-yielding LAW boundaries [pillar-anchored repairs (PARs)] would provide more durable reconstructions with lower hernia recurrence and bulge occurrence rates compared to mesh repairs anchored to the surrounding oblique muscle complexes [direct repairs (DRs)].

Study Design: We retrospectively reviewed LAW reconstructions at a single center from 2004-2010. Read More

Dis Esophagus 2019 Apr 17. Epub 2019 Apr 17.

Department of Medicine, Columbia University Medical Center, New York, USA.

Quality indicators have been proposed for endoscopic eradication therapy of Barrett's esophagus (BE). One such measure suggests that complete eradication of intestinal metaplasia (CE-IM) should be achieved within 18 months of starting treatment. The aim of this study was to assess whether achievement of CE-IM within 18 months is associated with improved long-term clinical outcomes. Read More

J Surg Case Rep 2019 Apr 10;2019(4):rjz107. Epub 2019 Apr 10.

Joondalup Health Campus, Western Australia.

The presence of the gallbladder in a parastomal hernia is exceeding rare. We present the case of a 75-year-old female with a parastomal hernia complicated by presence of the gallbladder. The patient was managed with surgical intervention to repair the hernia and reduce the gallbladder to its correct abdominal position without cholecystectomy. Read More

JSLS 2019 Jan-Mar;23(1)

Department of Surgery, Aspirus Iron River Hospital and Clinics, Iron River, Michigan, USA.

Background And Objectives: An aberrant left hepatic artery (ALHA) limits the already confined operative field of laparoscopic antireflux surgery (LARS) and laparoscopic hiatal hernia repair (LHHR). The aim of this study is to provide a safe laparoendoscopic technique for hiatal hernia repair in the presence of an ALHA.

Methods: We conducted a retrospective chart review of patients who underwent LARS or LHHR between March 2016 and March 2018. Read More

Beijing Da Xue Xue Bao Yi Xue Ban 2019 Apr;51(2):256-259

Department of Interventional Radiologyand Vascular Surgery, Peking University Third Hospital, Beijing 100191, China.

Objective: To evaluate the effectiveness and safety of mechanical thrombectomy treatment in patients with acute ischemic stroke (AIS),and to explore influential factors of the clinical prognosis preliminarily.

Methods: Clinical data of 26 patients with acute cerebral arterial occlusion treated with mechanical thrombectomy in Peking University Third Hospital from January 2014 to June 2017 were retrospectively collected. The immediate effects of the 26 patients in this group after mechanical thrombectomy treatment were analyzed,The national institutes of health stroke scale (NIHSS) scores between preoperative and at discharge of the 26 patients in this group were compared,and modified Rankin scale (mRS) scores of 90 days post operation were analyzed to assess the prognosis of the 26 patients in this group. Read More

Agri 2019 Apr;31(2):104-106

Department of Anesthesiology and Reanimation, Pain Clinic, Ege University, Izmir, Turkey.

Transforaminal epidural steroid injections are a common intervention in the treatment of radicular pain. Complications are rare, but can be catastrophic. One of the potentially devastating complications is occlusion of the artery of Adamkiewicz (AKA). Read More

PLoS One 2019 17;14(4):e0214793. Epub 2019 Apr 17.

Department of Development and Regeneration, Division Organ Systems, KU Leuven, Leuven, Belgium.

Background: Pulmonary hypoplasia, characterized by incomplete alveolar development, remains a major cause of mortality and morbidity in congenital diaphragmatic hernia. Recently demonstrated to differentiate from a common bipotent progenitor during development, the two cell types that line the alveoli type 1 and type 2 alveolar cells have shown to alter their relative ratio in congenital diaphragmatic hernia lungs.

Objective: We used the nitrofen/bisdiamine mouse model to induce congenital diaphragmatic hernia and accurately assess the status of alveolar epithelial cell differentiation in relation to the common bipotent progenitors. Read More

Br J Surg 2019 Apr 17. Epub 2019 Apr 17.

Department of Surgery, Elisabeth TweeSteden Hospital, Tilburg, the Netherlands.

Background: The short-term results of the TULIP trial comparing transinguinal preperitoneal (TIPP) inguinal hernia repair with the Lichtenstein method have been reported with follow-up of 1 year. After TIPP repair, fewer patients had chronic postoperative inguinal pain (CPIP); they had better health status and lower costs. The present study reports the long-term outcomes of this trial. Read More

Hernia 2019 Apr 16. Epub 2019 Apr 16.

Department of Hernia and Abdominal Wall Surgery, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, China.

Objective: The aim of this study is to evaluate the surgical outcomes of single-port laparoscopic percutaneous extraperitoneal closure of inguinal hernia using "two-hooked" core needle apparatus in children.

Methods: This study was conducted at Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine between January 2016 and June 2018. Five hundred and eighteen patients under the age of 12 years with inguinal hernias were subjected to single-port laparoscopic percutaneous extraperitoneal closure (SPLPEC) using non-absorbable suture by "two-hooked" core needle apparatus. Read More

Breastfeed Med 2019 Apr 16. Epub 2019 Apr 16.

5 Department of Neonatology, Thoracic, and Fetal Surgery, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.

Objective: This study explores the congenital diaphragmatic hernia (CDH) infant-mother dyad with regard to maternal lactation outcomes and infant exposure to a human milk diet.

Study Design: This was a retrospective descriptive cohort study conducted at Children's Hospital of Philadelphia. A total of 149 infants born with CDH and admitted to the Newborn/Infant Intensive Care Unit (N/IICU) were included in the study. Read More

Br J Surg 2019 Mar 20. Epub 2019 Mar 20.

Department of General Surgery, Ulster Hospital, Dundonald, BT16 1RH, UK.

Background: Inguinal hernia repair is a common low-risk intervention. Patient-reported outcomes (PROs) are being used increasingly as primary outcomes in clinical trials. The aim of this study was to review and meta-analyse the PROs in RCTs comparing laparoscopic versus open inguinal hernia repair techniques in adult patients. Read More

Expert Rev Clin Immunol 2019 Apr 16. Epub 2019 Apr 16.

a Departments of Clinical and Translational Science , Creighton University School of Medicine , Omaha , USA.

Introduction: Incisional hernias (IH) arise as a complication of patients undergoing a laparotomy. Current literature has assessed the role of extracellular matrix (ECM) disorganization, alterations in type I and type III collagen, matrix metalloproteinases, and tissue inhibitors of metalloproteases on IH. However, there is limited information on the underlying molecular mechanisms that lead to ECM disorganization. Read More

J Am Vet Med Assoc 2019 May;254(9):1099-1104

Case Description: A 1-year-old spayed female domestic shorthair cat was evaluated for a sternal defect and ventral abdominal wall hernia.

Clinical Findings: The cat appeared healthy. Palpation revealed a sternal defect, and the heart could be observed beating underneath the skin at the caudoventral aspect of the thorax. Read More

Hum Mol Genet 2019 Apr 1. Epub 2019 Apr 1.

Department of Human Genetics.

Disorders of sex development (DSDs) are defined as congenital conditions in which chromosomal, gonadal or anatomical sex is atypical. In many DSD cases, genetic causes remain to be elucidated. Here, we performed a case-control exome sequencing study comparing gene-based burdens of rare damaging variants between 26 DSD cases and 2625 controls. Read More

Medicine (Baltimore) 2019 Apr;98(15):e15192

Department of Neurosurgery, Erzincan Binali Yildirim University Medical Faculty, Başbağlar Mah, Center of City Erzincan, Turkey.

Background: This is an immunohistologic study of gene expression between patients and controls.This study aims to evaluate expression of the catalase gene in hypertrophied ligamentum flavum (LF) specimens obtained from patients with lumbar spinal canal stenosis (LSCS).LSCS is one of the most common spinal disorders. Read More

Medicine (Baltimore) 2019 Apr;98(15):e15037

Department of Hepatobiliary and Abdominal Hernias Surgery, Weihai Central Hospital, Weihai, Shandong Province, People's Republic of China.

Rationale: Herpes zoster infection typically involves the posterior root ganglia and most of the symptoms are sensory. Motor involvement can occur in the same distribution but is relatively uncommon. Segmental zoster paresis is a rare motor complication of Herpes zoster, mimicking an abdominal hernia, but it needs no surgery different from the real abdominal wall hernia. Read More

Ann Surg 2019 May;269(5):e67-e68

Cleveland Clinic, Cleveland, OH.

Ann Surg 2019 May;269(5):e67

Digestive Disease Center, Bispebjerg University Hospital, Copenhagen, Denmark.

J Laparoendosc Adv Surg Tech A 2019 Apr 13. Epub 2019 Apr 13.

2 Department of General Surgery, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China.

Introduction: The self-adhesive mesh has become increasingly popular since its launch and has been proven to be reliable in laparoscopic hernia reparation. However, self-adhesive mesh may encounter unexpected adhesions during operation because one side of the mesh was covered with microgrips.

Objective: Performing a modified technique of self-adhesive mesh implantation to avoid unexpected adhesions to the mesh itself and to the surrounding tissues in the operation space. Read More

Ultrasound Obstet Gynecol 2019 Apr 15. Epub 2019 Apr 15.

Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria.

Objectives: To assess the clinical feasibility and validity of fetal MRI-based 3D reconstructions to localize, classify, and quantify diaphragmatic defects in congenital diaphragmatic hernia (CDH).

Methods: Manual segmentation of the diaphragm based on 65 in vivo and four postmortem fetal MRI scans of 46 CDH cases (gestational age 16 - 38 gestational weeks (GW)) was performed using SSFP, T2-weighted, and T1-weighted sequences and ITK-Snap. The resultant 3D models of the fetal diaphragm and its defect(s) were validated by postmortem MRI segmentation in four cases and/or comparison to a reference classification based on autopsy and surgery reports. Read More

J Transcult Nurs 2019 Apr 15:1043659619841672. Epub 2019 Apr 15.

3 Hubei University of Medicine, Shiyan, Hubei, PRC.

Introduction: Based on the current medical environment in China, this study developed a WeChat-based health education program for parents of children undergoing day surgery herniorrhaphy and evaluated the users' satisfaction of its usage by adapting the technology acceptance model.

Methodology: A descriptive quantitative online design with a researcher-developed Satisfaction Questionnaire was used to survey 198 users in the university-affiliated hospital in China.

Results: The users were generally satisfied with the program. Read More

Fetal Diagn Ther 2019 Apr 12:1-8. Epub 2019 Apr 12.

Department of Pediatric Surgery, Karolinska University Hospital, Stockholm, Sweden.

Background: The etiology of congenital diaphragmatic hernia (CDH) remains poorly understood. We hypothesize that environmental factors play an important role in the development of CDH.

Aim: The objective of this study was to investigate associated maternal risk factors in pregnancies with CDH. Read More