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Front Med (Lausanne) 2021 16;8:760607. Epub 2021 Dec 16.

Department of Hepatobiliary Surgery II, Zhujiang Hospital, Southern Medical University, Guangzhou, China.

Biliary cystadenomas are rare cystic tumors of the bile duct system that are mostly benign but also have the possibility of malignant transformation. Biliary cystadenomas mostly occur in the intrahepatic bile ducts and are more common in middle-aged women. Due to non-specific radiology, preoperative diagnosis is difficult and is usually performed by postoperative pathology. Read More

Front Surg 2021 2;8:681012. Epub 2021 Dec 2.

Department of General and Hepatobiliary Surgery, Ziv Medical Center, Safed, Israel.

Cystic liver lesions may be benign cysts, parasitic infestations, or malignant tumors requiring surgical resection. Hilar location and relation to major vasculature present challenges in conventional surgical access and resection. We describe totally robotic excision of a cystadenoma in a 55-year-old woman without complication. Read More

Korean J Gastroenterol 2021 11;78(5):300-304

Department of Internal Medicine, Dankook University College of Medicine, Cheonan, Korea.

Neuroendocrine tumors (NETs) can arise throughout the body. Most NETs in the liver are metastatic tumors; primary hepatic NET (PHNET) is extremely rare. A diagnosis of PHNET is very difficult. Read More

Am Surg 2021 Nov 22:31348211054077. Epub 2021 Nov 22.

Division of Abdominal Transplant, Department of Surgery, 2332University of North Carolina, Chapel Hill, NC, USA.

Background And Aims: Simple liver cyst (SHC) is a benign condition with no malignant potential. They are typically discovered incidentally due to the increased use of abdominal imaging, but some patients may present with abdominal pain. A radiologist's differential diagnosis in cases of SHC will often include "rule out biliary cystadenoma. Read More

Nucl Med Mol Imaging 2021 Oct 23;55(5):257-260. Epub 2021 Aug 23.

National Cyclotron and PET Centre, Chulabhorn Hospital, Chulabhorn Royal Academy, Kamphangpetch 6 Road, Laksi Bangkok, 10210 Thailand.

A patient with intrahepatic cholangiocarcinoma who underwent hepatic resection with completed neoadjuvant chemotherapy presented with increased CEA levels. Previous whole abdominal and chest CT scan revealed no evidence of local recurrence or metastasis.  Ga-FAPI-46 PET showed significantly higher tumor-to-background contrast of recurrent tumor and nodal metastasis, which were undetectable in the FDG PET or conventional CT scan. Read More

World J Clin Cases 2021 Sep;9(26):7886-7892

Department of Ultrasonography, Shaoxing People's Hospital (Shaoxing Hospital, Zhejiang University School of Medicine), Shaoxing 312000, Zhejiang Province, China.

Background: Intrahepatic biliary cystadenoma (IBC) is a rare benign hepatic tumor that is often misdiagnosed as other hepatic cystic diseases. Therefore, imaging examinations are required for preoperative diagnosis. Contrast-enhanced ultrasound (CEUS) has gained increasing popularity as an emerging imaging modality and it is considered the primary method for screening IBC because of its specificity of performance. Read More

Ultrasound 2021 Aug 31;29(3):187-192. Epub 2021 Jan 31.

Surgical Oncology, Peter MacCallum Cancer Centre, Parkville, Australia.

Introduction: Intracystic haemorrhage is a rare complication of hepatic cysts, and is often mistaken for a malignant lesion.

Case Report: A 55-year-old female with a history of polycystic kidney and liver disease presented with a six-month history of abdominal distension, abdominal pain, early satiety, shortness of breath and 5 kg of weight loss. Imaging revealed a 20 cm mixed solid-cystic hepatic lesion containing peripheral avascular mobile echogenic material with a flame-like morphology. Read More

J Gastrointest Surg 2021 10 9;25(10):2700-2706. Epub 2021 Sep 9.

Section of Transplantation Surgery, Siteman Cancer Center, Barnes-Jewish Hospital, and Washington University School of Medicine in St. Louis, St Louis, MO, USA.

Background: Biliary cystadenomas are very rare benign tumors which can transform into cystadenocarcinomas. The largest case series reported on 221 cases over 30 years from 10 HPB centers, i.e. Read More

Rev Med Liege 2021 Sep;76(9):661-665

Service de Chirurgie abdominale et Transplantation, CHU Liège, Belgique.

Cystic hepatic lesions are frequent and sometimes large. They are generally asymptomatic and discovered by chance. The differential diagnosis of these lesions includes congenital, post-traumatic, benign or malignant tumors, as well as infectious pathologies. Read More

Mol Clin Oncol 2021 Oct 29;15(4):196. Epub 2021 Jul 29.

First Department of Surgery, National and Kapodistrian University of Athens, Laikon General Hospital, 11527 Athens, Greece.

Biliary mucinous cystic neoplasms are very rare tumors of the biliary tract with malignant potential. Preoperative diagnosis is challenging, as clinical, biochemical and radiological features are not specific. Surgical resection with negative margins is the gold standard treatment for these uncommon lesions. Read More

Arch Iran Med 2021 04 1;24(4):301-305. Epub 2021 Apr 1.

Department of Pathology, Dr. Lutfi Kirdar Kartal Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.

Background: Ectopic adrenal tissue is a rare condition associated with embryological development defects seen in many different areas in the abdomen and pelvis. Here, we aimed to discuss the clinicopathological features of ectopic adrenal tissues diagnosed in our clinic, in light of the literature.

Methods: We included cases of ectopic adrenal tissues incidentally detected in the specimens from patients undergoing operation for various diagnoses during 2012- March 2020. Read More

Case Rep Surg 2021 21;2021:9977326. Epub 2021 May 21.

Department of General and Digestive Surgery A at the University Hospital Charles Nicolle, University of Tunis el Manar, Tunisia.

Hydatidosis is a widespread anthropozoonosis. It can affect almost any part of the body, but it occurs most commonly in the liver (75%) and the lungs (15%). Its occurrence in female genital tract, especially the uterus, is very rare. Read More

Pan Afr Med J 2021 9;38:144. Epub 2021 Feb 9.

Service de Chirurgie Viscérale et Oncologie Digestive A, Centre Hospitalier Universitaire Mohammed VI, Oujda, Maroc.

Congenital cystic disease of the biliary tree is a known risk factor for gallbladder cancer. We here report a case of squamous cell carcinoma of the bile duct (BD) complicating a cystic dilatation of the bile ducts in a 54-year-old woman hospitalized for biliary pancreatitis. Abdominal scanner showed nodular thickening of the fundus of the gallbladder and fusiform dilation of the cystic duct and the main bile duct (VBP) with lesion of the tail of the pancreas, initially suggesting mucinous cystadenoma. Read More

Pancreas 2021 03;50(3):434-440

From the Division of Surgical Oncology, Department of Surgery.

Abstract: The incidence of pancreatic cystic neoplasms has grown because of increased detection. Among these lesions, serous cystadenoma was traditionally thought to be universally benign and indolent. However, there is an exceedingly rare malignant variant of serous cystadenoma known as serous cystadenocarcinoma (SCAC) that can exhibit local invasion into adjacent structures, hepatic implants, and metastatic spread to the abdominal viscera. Read More

Am J Case Rep 2021 Apr 3;22:e931368. Epub 2021 Apr 3.

Department of Surgery, Shiga General Hospital, Moriyama, Shiga, Japan.

BACKGROUND Mucinous cystic neoplasm (MCN) of the liver is a rare hepatic neoplasm: a cystic, mucus-producing tumor. Histopathologic examination reveals ovarian-like stroma. The origin of MCN of the liver is still unknown, although ectopic ovarian-like stroma in the liver has been suggested as a possibility. Read More

BMC Surg 2021 Mar 20;21(1):146. Epub 2021 Mar 20.

Department of General Surgery, School of Medicine, Sir Run Run Shaw Hospital, Zhejiang University, 3 East Qingchun Road, Hangzhou, 310016, Zhejiang, China.

Background: Hepatobiliary mucinous cystic neoplasms (H-MCNs) are relatively rare cystic neoplasms in the liver. The differential diagnosis of H-MCNs remains big challenging, and the management and prognosis between the hepatic simple cyst (HSC) and H-MCNs are quite different. This study aimed to present our experience in the management of H-MCNs and provide a preoperative H-MCNs risk prediction nomogram to differentiating H-MCNs from liver cystic lesions. Read More

BMC Gastroenterol 2021 Feb 23;21(1):84. Epub 2021 Feb 23.

Department of Hepatobiliary Surgery, The Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, People's Republic of China.

Background: Hepatic cavernous hemangioma is the most common type of benign liver tumor. Although ruptures and hemorrhages of hepatic hemangioma are rare complications, they are associated with high mortality. Most practitioners only pay more attention to abdominal hemorrhages caused by the rupture of hepatic hemangiomas. Read More

Dig Dis Sci 2021 11 6;66(11):4063-4067. Epub 2021 Jan 6.

Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.

Ann Med Surg (Lond) 2021 Jan 3;61:13-15. Epub 2020 Dec 3.

Department of Faculty Surgery №1 of I.M. Sechenov, First Moscow State Medical University (Sechenov University), Russia.

Hepatic cystadenoma is an urgent problem due to the high risk of malignant transformation. There are both radical and minimally invasive methods of treatment. We present a clinical case describing the successful use of microwave ablation (MWA) in a 72-year-old woman with hepatic cystadenoma. Read More

World J Clin Cases 2020 Nov;8(22):5670-5677

Department of Radiology, First Hospital of Shanxi Medical University, Taiyuan 030001, Shanxi Province, China.

Background: Biliary cystadenoma (BCA) is a rare benign tumor, accounting for only 5% of reported cystic lesions of the liver. Given its potential for malignancy and high rate of recurrence, surgical resection is the preferred treatment. Therefore, early and accurate preoperative diagnosis is critical to the choice of treatment. Read More

BMC Surg 2020 Dec 11;20(1):328. Epub 2020 Dec 11.

Division of Liver Transplant Surgery, Samaritano Higienopolis Hospital, São Paulo, Brazil.

Background: Mucinous cyst neoplasm of the liver (MCN-L) comprise less than 5% of all cystic liver lesions and is characterized by the presence of ovarian stroma and absence of bile duct communication.

Case Presentation: Here, we discuss a 45-year-old woman who presented with symptomatic liver mass. Diagnostic workup detected a 4. Read More

Rev Esp Enferm Dig 2021 Jun;113(6):470

Aparato Digestivo, Complejo Hospitalario Universitario de A Coruña.

We present the case of a 55-year-old female with no history of interest and asymptomatic, who was admitted to perform studies due to findings of an abdominal ultrasound. A dilated left intrahepatic bile duct and a segment of the common hepatic duct, the proximal bile duct, was identified with irregular thickening of the wall, with an increased caliber (12 mm). A cystic lesion of 6 x 5. Read More

Clin J Gastroenterol 2021 Feb 20;14(1):258-262. Epub 2020 Nov 20.

Department of Digestive Surgery, CHU Amiens and University of Picardie, 1 rue du Professeur Christian Cabrol, 80054, Amiens cedex, France.

Simple hepatic cysts are very common, but may be difficult to differentiate from a biliary cystadenoma or cystadenocarcinoma. Because the surgical treatment if needed, such as a hepatic fenestration or resection, depends on the diagnosis, the assay of intracystic tumor markers is useful.We report the case of a 67-year-old woman with a large hepatic cyst responsible of pain and inflammation. Read More

J Gastrointest Surg 2021 01 20;25(1):77-84. Epub 2020 Oct 20.

Department of Surgery, University of California San Francisco, 533 Parnassus Avenue, Room 370, San Francisco, CA, USA.

Background: Hepatic cyst disease is often asymptomatic, but treatment is warranted if patients experience symptoms. We describe our management approach to these patients and review the technical nuances of the laparoscopic approach.

Methods: Medical records were reviewed for operative management of hepatic cysts from 2012 to 2019 at a single, tertiary academic medical center. Read More

Zhonghua Wai Ke Za Zhi 2020 Jul;58(7):512-515

Department of Gastroenterology and Pancreatic Surgery, Zhejiang Province People's Hospital, Key Laboratory of Gastroenterology of Zhejiang Province, Hangzhou 310014, China.

To summarize the characteristics and difficulties of minimal invasive surgery for adolescent with pancreatic head tumor. The data of adolescent younger than 28 years old with pancreatic head tumor treated at Department of Gastroenterology and Pancreatic Surgery, Zhejiang Province People's Hospital from January 2014 to December 2019 were analyzed retrospectively. Fifteen cases were enrolled, included 5 males and 10 females. Read More

In Vivo 2020 Jul-Aug;34(4):2067-2071

Department of Surgery, Yamaga City Medical Center, Kumamoto, Japan.

Background/aim: Hepatic xanthogranuloma is a very rale disease and formation process is unknown.

Case Report: A 69-year-old woman previously diagnosed as simple liver cyst. Two years before, a 36-mm liver cyst was found in segment 5, while one year later, the hemorrhagic cyst was 40 mm in diameter and a thin septum had formed. Read More

Cir Esp (Engl Ed) 2021 Jan 19;99(1):27-33. Epub 2020 May 19.

Unidad de Cirugía Hepato-Bilio-Pancreática y Trasplante de Órganos Abdominales, Servicio de Cirugía General, Hospital Universitario 12 de Octubre, Madrid, España; Departamento de Cirugía, Facultad de Medicina, Universidad Complutense de Madrid, Madrid, España.

Introduction: The hepatic cystic tumour is a very rare neoplasm, representing about 5% of all cystic liver neoplasms. The preoperative diagnosis is difficult and can lead to confusion. The aim of this study is to analyze a number of cases operated at our centre with an histologic diagnosis of liver cystic neoplasms and also to describe the sintomathology, diagnosis and management as per the recent classification. Read More

J Gastroenterol Hepatol 2020 Jul 3;35(7):1098. Epub 2020 May 3.

Organ Transplantation Center, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, Sichuan, China.

Ann Surg Oncol 2020 Oct 7;27(10):3926-3927. Epub 2020 Apr 7.

Department of Pancreatic Surgery, West China Hospital, Sichuan University, Chengdu, China.

Background: In 1972, Beger et al.1 first described duodenum-preserving pancreatic head resection (DPPHR) for patients with severe chronic pancreatitis. Then DPPHR also was proved capable of providing comparable long-term oncologic outcomes in the setting of benign or low-grade malignant tumors. Read More