4,500 results match your criteria Hepatic Adenoma


[ABDOMINAL MASS AND ASCITES AS RISK FACTORS OF PELVIC ORGAN PROLAPSE].

Nihon Hinyokika Gakkai Zasshi 2018 ;109(2):96-101

Department of Urology, Japanese Red Cross Nagoya First Hospital.

(Objective) A rise of intra-abdominal pressure may exacerbate pelvic organ prolapse (POP) as well as abdominal hernias. This paper aims to assess the possible risk factors of an abdominal mass and ascites as comorbidities of POP. (Methods) We retrospectively reviewed the medical charts of 2,748 POP patients between 2010 and 2016 and extracted eight cases (0. Read More

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https://www.jstage.jst.go.jp/article/jpnjurol/109/2/109_96/_
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http://dx.doi.org/10.5980/jpnjurol.109.96DOI Listing
January 2018
1 Read

Hepatic complications of oral contraceptive pills and estrogen on MRI: Controversies and update - Adenoma and beyond.

Magn Reson Imaging 2019 Apr 19. Epub 2019 Apr 19.

Wake Forest University and Baptist Health, Medical Center Boulevard, Winston-Salem, NC 27157, United States of America. Electronic address:

Hepatic complications of oral contraceptive pills and exogenous estrogens include intrahepatic canalicular cholestasis, neoplasm formation and vascular pathologies. While it remains controversial as to whether estrogen plays a role in focal nodular hyperplasia, hemangioma or hamartoma, exposure to oral contraceptive pills and estrogen has a strong association with hepatic adenomas. Four different subgroups of adenomas have been described: Inflammatory, HNF-1α-mutated, β-catenin-mutated and unclassified. Read More

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http://dx.doi.org/10.1016/j.mri.2019.04.010DOI Listing

Effect of lncRNA HULC knockdown on rat secreting pituitary adenoma GH3 cells.

Braz J Med Biol Res 2019 15;52(4):e7728. Epub 2019 Apr 15.

Department of Pain Clinic, The First Affiliated Hospital of Xiamen University, Fujian Medical University, Xiamen, Fujian, China.

Pituitary adenoma is one of the most common tumors in the neuroendocrine system. This study investigated the effects of long non-coding RNAs (lncRNAs) highly up-regulated in liver cancer (HULC) on rat secreting pituitary adenoma GH3 cell viability, migration, invasion, apoptosis, and hormone secretion, as well as the underlying potential mechanisms. Cell transfection and qRT-PCR were used to change and measure the expression levels of HULC, miR-130b, and FOXM1. Read More

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S
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http://dx.doi.org/10.1590/1414-431X20197728DOI Listing
April 2019
2 Reads

Hepatic disorders associated with exogenous sex steroids: MR imaging findings.

Abdom Radiol (NY) 2019 Apr 6. Epub 2019 Apr 6.

Monash Imaging, Monash Health, Melbourne, Australia.

Objective: To describe the MRI findings of the effects of exogenous sex steroids on the liver.

Findings: Estrogens, progesterone and synthetic testosterone are exogenous sex steroids that may result in a variety of liver diseases, including tumour formation and vascular disorders. These hormones are mainly administered in the form of the oral contraceptive pill (OCP) and anabolic steroids. Read More

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http://dx.doi.org/10.1007/s00261-019-01941-4DOI Listing
April 2019
2 Reads

Iso- or hyperintensity of hepatocellular adenomas on hepatobiliary phase does not always correspond to hepatospecific contrast-agent uptake: importance for tumor subtyping.

Eur Radiol 2019 Apr 1. Epub 2019 Apr 1.

Department of Radiology, APHP, HU Henri Mondor, Creteil, Val-de-Marne, France.

Purpose: This study was conducted in order to evaluate if iso- or hyperintensity of HCAs on HBP is systematically related to a high uptake of hepatospecific contrast agent, using a quantitative approach.

Methods: This bicentric retrospective study included all patients with histologically confirmed and subtyped HCA from 2009 to 2017 who underwent MRI with HBP after Gd-BOPTA injection and who showed iso- or hyperintensity on HBP. The signal intensity of tumors on pre- and postcontrast images and the presence of hepatic steatosis were noted. Read More

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http://dx.doi.org/10.1007/s00330-019-06150-7DOI Listing
April 2019
3 Reads

Hepatic CYP1A2 activity in liver tumors and the implications for preoperative volume-function analysis.

Am J Physiol Gastrointest Liver Physiol 2019 Mar 14. Epub 2019 Mar 14.

Department of General, Visceral- and Transplantation Surgery, Charité - Universitätsmedizin Berlin.

Dynamic liver function assessment by the C-methacetin maximal liver function capacity (LiMAx) test reflects the overall hepatic CYP1A2 activity. One proven strategy for preoperative risk assessement in liver surgery includes the combined assessment of the dynamic liver function by the LiMAx test, the volumetric analysis of the liver and calculation of future liver remnant function. This so-called volume-function analysis assumes that the remaining CYP1A2 activity in any tumor lesion is zero. Read More

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http://dx.doi.org/10.1152/ajpgi.00335.2018DOI Listing
March 2019
1 Read

Benign liver tumors

Rev Prat 2018 12;68(10):1119-1124

Service d'hépatologie.

Benign liver tumors diagnosis. Benign liver tumors are rare events that affect mostly young women. Hepatic hemangioma and focal nodular hyperplasia are not related to oral contraceptions, nor associated with complications, and consequently should not either be treated or followed-up. Read More

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December 2018
2 Reads

Surgical indications for focal nodular hyperplasia of the liver: Single-center experience of 48 adult cases.

Ann Hepatobiliary Pancreat Surg 2019 Feb 28;23(1):8-12. Epub 2019 Feb 28.

Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Backgrounds/aims: Focal nodular hyperplasia (FNH) is one of the most common benign tumors of the liver. There is still a lack of evidence on surgical indications for FNH. This study intended to analyze the surgical indications for FNH. Read More

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http://dx.doi.org/10.14701/ahbps.2019.23.1.8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405369PMC
February 2019
2 Reads

Identification of key challenges in liver pathology: data from a multicenter study of extramural consults.

Hum Pathol 2019 Mar 8. Epub 2019 Mar 8.

Department of Pathology, University of Washington Medical Center, Seattle, WA, USA.

Extramural consultation for challenging pathology cases is an important part of patient care. The specific reasons why liver cases are submitted in consultation are poorly understood. To study patterns in extramural consultation, data were gathered from 1360 liver/GI/pancreatobiliary consults submitted to 7 academic centers. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00468177193003
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http://dx.doi.org/10.1016/j.humpath.2019.03.001DOI Listing
March 2019
9 Reads

Glycemic control and complications in glycogen storage disease type I: Results from the Swiss registry.

Mol Genet Metab 2019 Feb 28. Epub 2019 Feb 28.

Department of Endocrinology, Diabetes, and Clinical Nutrition, University Hospital Zurich, Zurich, Switzerland; radiz - Rare Disease Initiative Zurich, Clinical Research Priority Program for Rare Diseases, University of Zurich, Switzerland. Electronic address:

Background: Regular carbohydrate intake to avoid hypoglycemia is the mainstay of dietary treatment in glycogen storage disease type I (GSDI). The aim of this study was to evaluate the quality of dietary treatment and glycemic control in a cohort of GSDI patients, in relation to the presence of typical long-term complications.

Methods: Data of 25 patients (22 GSD subtype Ia and 3 GSDIb, median age 20y) from the Swiss hepatic glycogen storage disease registry was analyzed cross-sectionally. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10967192193003
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http://dx.doi.org/10.1016/j.ymgme.2019.02.008DOI Listing
February 2019
12 Reads

A case of hepatocellular carcinoma mimicking hepatic adenoma.

Ann Ital Chir 2019 Feb 26;8. Epub 2019 Feb 26.

Hepatocellular adenomas (HA) are benign naturally occurring masses that are rarely reported, and rarely reaching tumor size up to 30 cm. Hepatocellular carcinoma (HCC) is the most common primary malignancy of the liver and usually caused by cirrhosis and more commonly reported tumors in males. It has been reported that presentations may occur with masses that are often less than 5 cm or rarely more than 10 cm. Read More

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February 2019
4 Reads

promotes colorectal cancer by inducing Wnt/β-catenin modulator Annexin A1.

EMBO Rep 2019 Apr 4;20(4). Epub 2019 Mar 4.

Division of Periodontics, College of Dental Medicine, Columbia University, New York, NY, USA

, a Gram-negative oral anaerobe, is a significant contributor to colorectal cancer. Using an cancer progression model, we discover that stimulates the growth of colorectal cancer cells without affecting the pre-cancerous adenoma cells. Annexin A1, a previously unrecognized modulator of Wnt/β-catenin signaling, is a key component through which exerts its stimulatory effect. Read More

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http://dx.doi.org/10.15252/embr.201847638DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446206PMC
April 2019
9.055 Impact Factor

Two-stage liver transplant for ruptured hepatic adenoma: A case report.

World J Hepatol 2019 Feb;11(2):242-249

Division of Surgical Transplantation, Department of Surgery, the University of Texas Southwestern Medical Center, Dallas, TX 75390, United States.

Background: Only one case of liver transplantation for hepatic adenoma has previously been reported for patients with rupture and uncontrolled hemorrhage. We present the case of a massive ruptured hepatic adenoma with persistent hemorrhagic shock and toxic liver syndrome which resulted in a two-stage liver transplantation. This is the first case of a two-stage liver transplantation performed for a ruptured hepatic adenoma. Read More

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http://dx.doi.org/10.4254/wjh.v11.i2.242DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393718PMC
February 2019
1 Read

Utilization of spectrins βI and βIII in diagnosis of hepatocellular carcinoma.

Ann Diagn Pathol 2019 Feb 15;39:86-91. Epub 2019 Feb 15.

Department of Pathology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY 10467, United States of America. Electronic address:

Spectrins are a group of cytoskeletal proteins which participate in many important cellular functions. It has been suggested that loss of spectrin isoforms may be associated with tumorigenesis of lymphoma, leukemia, gastric cancer and hepatocellular carcinoma (HCC). We recently reported that βI spectrin expression was present in normal hepatocytes but lost in HCC cells, which suggested that spectrins may be helpful markers in diagnosis of HCC. Read More

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http://dx.doi.org/10.1016/j.anndiagpath.2019.02.009DOI Listing
February 2019
3 Reads

FXR Regulates Intestinal Cancer Stem Cell Proliferation.

Cell 2019 Feb;176(5):1098-1112.e18

Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037, USA; Howard Hughes Medical Institute, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA. Electronic address:

Increased levels of intestinal bile acids (BAs) are a risk factor for colorectal cancer (CRC). Here, we show that the convergence of dietary factors (high-fat diet) and dysregulated WNT signaling (APC mutation) alters BA profiles to drive malignant transformations in Lgr5-expressing (Lgr5) cancer stem cells and promote an adenoma-to-adenocarcinoma progression. Mechanistically, we show that BAs that antagonize intestinal farnesoid X receptor (FXR) function, including tauro-β-muricholic acid (T-βMCA) and deoxycholic acid (DCA), induce proliferation and DNA damage in Lgr5 cells. Read More

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http://dx.doi.org/10.1016/j.cell.2019.01.036DOI Listing
February 2019
1 Read
32.242 Impact Factor

Hepatic adenoma during pregnancy and anesthetic management.

Int J Obstet Anesth 2019 Jan 12. Epub 2019 Jan 12.

Montefiore Medical Center, Jack D Weiler Hospital, Department of Obstetric Anesthesiology, 1825 Eastchester Road, Bronx, NY 10461, United States of America. Electronic address:

We report the case of a 24-year-old woman with a large hepatic adenoma diagnosed in the third trimester of pregnancy. The adenoma was at risk of rupture. She underwent scheduled preterm cesarean delivery under combined spinal-epidural anesthesia, followed by transarterial embolization on postpartum day six. Read More

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http://dx.doi.org/10.1016/j.ijoa.2019.01.007DOI Listing
January 2019
4 Reads

Acromegaly associated with GIST, non-small cell lung cancer, clear cell renal cancer, myeloma multiplex, medulla oblongata tumor, adrenal adenoma and follicular thyroid nodules.

Endokrynol Pol 2019 Feb 11. Epub 2019 Feb 11.

Dept. of Endocrinology, Diabetes and Isotope Therapy, Medical University Wroclaw, Pasteura 4, 50-367 Wrocłąw, Poland.

Background: Acromegaly is associated with increased growth hormone (GH) and insulin-like growth factor-I (IGF-I) secretion which may support tumor development and growth.

Case Presentation: A 68-year old woman was diagnosed with acromegaly due to typical clinical and hormonal characteristics. While a contrast-enhanced MRI at diagnosis did not reveal a pituitary adenoma, a 5 mm lesion was identified on repeat scanning 13 months later. Read More

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http://dx.doi.org/10.5603/EP.a2019.0005DOI Listing
February 2019
7 Reads

[Hepatic metastasis of a pleomorphic adenoma].

Medicina (B Aires) 2019 ;79(1):64-66

Servicio de Cirugía General, Hospital Alemán, Buenos Aires, Argentina.

Pleomorphic adenoma is the most benign tumor of the salivary glands. It can undergo a malignant transformation to carcinoma and metastasize to distant organs, sometimes it can metastasize as a benign tumor. We present the case of an 82 years old male with hepatic lesion detected by ultrasound in routine urologic follow-up. Read More

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January 2019
13 Reads

Pilot study of rapid MR pancreas screening for patients with BRCA mutation.

Eur Radiol 2019 Jan 28. Epub 2019 Jan 28.

Department of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA.

Purpose: To develop and optimize a rapid magnetic resonance imaging (MRI) screening protocol for pancreatic cancer to be performed in conjunction with breast MRI screening in breast cancer susceptibility gene (BRCA)-positive individuals.

Methods: An IRB-approved prospective study was conducted. The rapid screening pancreatic MR protocol was designed to be less than 10 min to be performed after a standard breast MRI protocol. Read More

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http://link.springer.com/10.1007/s00330-018-5975-0
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http://dx.doi.org/10.1007/s00330-018-5975-0DOI Listing
January 2019
10 Reads

Liver Imaging Techniques: Recognition of Uveal Melanoma Metastases.

Ocul Oncol Pathol 2018 Jun 19;4(4):254-260. Epub 2018 Jan 19.

Cole Eye Institute, Cleveland Clinic, Cleveland, OH, USA.

Background: The liver is the most common site for metastases of several primary malignancies including uveal melanoma.

Methods: Review of imaging characteristics of incidental common benign liver lesions including hepatic cyst, hemangioma, focal nodular hyperplasia, and hepatic adenoma and contrasting them with uveal melanoma metastases.

Results: Benign hepatic lesions may be cystic or, if solid, relatively stable in size over time. Read More

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https://www.karger.com/Article/FullText/485424
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http://dx.doi.org/10.1159/000485424DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322083PMC
June 2018
7 Reads

Gene therapy prevents hepatic tumor initiation in murine glycogen storage disease type Ia at the tumor-developing stage.

J Inherit Metab Dis 2019 Jan 14. Epub 2019 Jan 14.

Section on Cellular Differentiation, Division of Translational Medicine, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, Maryland.

Hepatocellular adenoma/carcinoma (HCA/HCC) is a long-term complication of glycogen storage disease type-Ia (GSD-Ia), which is caused by a deficiency in glucose-6-phosphatase-α (G6Pase-α or G6PC), a key enzyme in gluconeogenesis. Currently, there is no therapy to address HCA/HCC in GSD-Ia. We have previously shown that a recombinant adeno-associated virus (rAAV) vector-mediated G6PC gene transfer to 2-week-old G6pc-/- mice prevents HCA development. Read More

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http://dx.doi.org/10.1002/jimd.12056DOI Listing
January 2019
3 Reads

Liver Metastasis of Hepatoid Colonic Adenocarcinoma: A Rare and Unusual Entity With Poor Prognosis and Review of the Literature.

Gastroenterology Res 2018 Dec 17;11(6):430-435. Epub 2018 Dec 17.

Department of Pathology, Immunology, and Laboratory Medicine, College of Medicine, University of Florida, Gainesville, FL, USA.

Hepatoid adenocarcinoma (HAC) is rare and was first reported as α-fetoprotein (AFP)-producing tumor. It is an important variant of extrahepatic adenocarcinoma with clinicopathological presentation mimicking hepatocellular carcinoma and carries exceedingly poor prognosis. HAC most commonly originates in the stomach, and less commonly in the ovary, esophagus, lung, among other organs. Read More

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http://dx.doi.org/10.14740/gr1097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306111PMC
December 2018
4 Reads

Impact of retroflexion in the right colon after repeated forward-view examinations.

JGH Open 2018 Dec 10;2(6):282-287. Epub 2018 Sep 10.

Department of Gastroenterology and Hepatology, Graduate School of Medical Sciences Kumamoto University Kumamoto Japan.

Background And Aim: Right colon polyps can especially be overlooked when they are located on the backs of haustral folds. Previous studies have reported that repeated forward-view examinations in the right colon were effective in reducing adenoma miss rates. The aim of this study was to clarify the impact of retroflexion in the right colon after repeated forward-view examinations. Read More

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http://dx.doi.org/10.1002/jgh3.12084DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6308076PMC
December 2018
1 Read

Association of raised levels of IL-4 and anti-TPO with hyperprolactinemia.

Am J Reprod Immunol 2019 Mar 30;81(3):e13085. Epub 2019 Jan 30.

Department of Obstetrics and Gynecology, All India Institute of Medical Sciences, New Delhi, India.

Background And Objective: The modulatory role of prolactin in autoimmune regulation is well established. Hyperprolactinemia is often associated with autoimmune disease like systemic lupus erythematosus and autoimmune thyroid diseases. The objective was to compare levels of direct and indirect autoimmune factors in different categories of hyperprolactinemia cases and predict the direction of association between hyperprolactinemia and autoimmune factors, if any. Read More

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http://dx.doi.org/10.1111/aji.13085DOI Listing
March 2019
4 Reads

Synchronous Unicentric Castleman Disease and Inflammatory Hepatocellular Adenoma: a Case Report.

Ann Hepatol 2018 Dec;18(1):263-268

Institute of Liver Studies, King's College Hospital, London, UK.

Systemic symptoms such as fever and fatigue are non-specific manifestations spanning from inflammation to neoplasia. Here we report the case of a 34 year-old man who presented with systemic symptoms for four months. CT-scan and MRI revealed a 3. Read More

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http://dx.doi.org/10.5604/01.3001.0012.7936DOI Listing
December 2018
4 Reads

Molecular Pathological Differences in Global Gene Expression between Two Sustained Proliferative Lesions, Nodular Regenerative Hepatocellular Hyperplasia and Hepatocellular Adenoma, in Mice.

Toxicol Pathol 2019 01 20;47(1):44-52. Epub 2018 Dec 20.

1 Division of Pathology, National Institute of Health Sciences, Kawasaki, Kanagawa, Japan.

Long-term exposure to piperonyl butoxide (PBO) induces multiple nodular masses along with hepatocellular tumors in the liver of mice. The histopathological features of the nodules led to our diagnosis of nodular regenerative hepatocellular hyperplasia (NRH). However, because of the lack of data on the biological characteristics of NRH, whether this lesion is truly nonneoplastic remains unknown. Read More

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http://dx.doi.org/10.1177/0192623318810200DOI Listing
January 2019
3 Reads

Evaluation of hepatic tumor portal perfusion using mesenteric angiography: A pilot study in 5 dogs.

J Vet Intern Med 2019 Mar 18;33(2):776-782. Epub 2018 Dec 18.

Lamb Statistical Consulting, West St. Paul, Minnesota.

Background: Mesenteric angiography is a sensitive method for visualizing portal perfusion in the dog.

Objectives: To evaluate hepatic portal perfusion in dogs with incompletely resectable hepatic tumors using mesenteric angiography.

Animals: Five client-owned dogs with incompletely resectable hepatic tumors evaluated with mesenteric angiography. Read More

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http://dx.doi.org/10.1111/jvim.15395DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430931PMC
March 2019
6 Reads

Value of Texture Analysis on Gadoxetic Acid-Enhanced MRI for Differentiating Hepatocellular Adenoma From Focal Nodular Hyperplasia.

AJR Am J Roentgenol 2019 Mar 17;212(3):538-546. Epub 2018 Dec 17.

1 Department of Radiology, Abdominal Imaging Division, University of Pittsburgh, 200 Lothrop St, Pittsburgh, PA 15213.

Objective: The objective of our study was to assess the diagnostic performance of texture analysis (TA) on gadoxetic acid-enhanced MR images for differentiation of hepatocellular adenoma (HCA) from focal nodular hyperplasia (FNH).

Materials And Methods: This study included 40 patients (39 women and one man) with 51 HCAs and 28 patients (27 women and one man) with 32 FNH lesions. All lesions were histologically proven with preoperative MRI performed with gadoxetic acid. Read More

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https://www.ajronline.org/doi/10.2214/AJR.18.20182
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http://dx.doi.org/10.2214/AJR.18.20182DOI Listing
March 2019
17 Reads

New MRI features improve subtype classification of hepatocellular adenoma.

Eur Radiol 2019 May 6;29(5):2436-2447. Epub 2018 Dec 6.

CHU de Bordeaux, Service d'imagerie diagnostique et interventionnelle, Hôpital Haut-Lévêque, F-33604, Pessac, France.

Objective: MRI is crucial for the classification of hepatocellular adenomas (HCA) into subtypes. Our objective was to review and increase MRI criteria for subtype classification and define the limits.

Methods: Pathological and radiological data of 116 HCAs were retrospectively analyzed to investigate MRI features of HCA pathological subtypes. Read More

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http://dx.doi.org/10.1007/s00330-018-5784-5DOI Listing
May 2019
4 Reads

Hepatocellular carcinoma: a review of diagnostic challenges for the pathologist.

Authors:
Alberto Quaglia

J Hepatocell Carcinoma 2018 8;5:99-108. Epub 2018 Nov 8.

Department of Cellular Pathology, Royal Free Hospital, London NW3 2QG, UK,

Histopathologists retain a critical role in the diagnosis and management of hepatocellular carcinoma (HCC). HCC arises usually but not exclusively in a background of advanced-stage chronic liver disease. The histological diagnosis of HCC poses many challenges particularly when dealing with liver biopsy specimens due to the heterogeneity of HCC and the difficulty to confirm hepatocellular differentiation in some instances. Read More

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http://dx.doi.org/10.2147/JHC.S159808DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235001PMC
November 2018
11 Reads

Rates of colorectal cancer detection in screening colonoscopy post appendicectomy in patients 50 years and over.

Ann Med Surg (Lond) 2018 Dec 20;36:239-241. Epub 2018 Nov 20.

Caboolture Hospital, 120 McKean Street, 4510, Queensland, Australia.

Introduction: Acute appendicitis in older adults is relatively uncommon and could be the first presentation of an underlying colorectal carcinoma. Colonoscopy in these individuals affords the opportunity for earlier diagnosis and treatment. The finding of increased rates of colorectal cancer (CRC) with older patients who have had appendicitis was supported by a number of small studies and case reports in the early 1980s. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S20490801183026
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http://dx.doi.org/10.1016/j.amsu.2018.11.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258134PMC
December 2018
10 Reads

[Heterotopic Salivary Gland Tissue at the Hepatic Flexure of the Large Intestine: A Case Report].

Korean J Gastroenterol 2018 Oct;72(4):213-216

Health Promotion Center, Dongkang Medical Center, Ulsan, Korea.

The occurrence of heterotopic tissue in the large intestine is unusual. The most common heterotopic tissue type described is gastric-type mucosa. On the other hand, heterotopic salivary gland tissue in the large intestine is extremely rare. Read More

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https://synapse.koreamed.org/DOIx.php?id=10.4166/kjg.2018.72
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http://dx.doi.org/10.4166/kjg.2018.72.4.213DOI Listing
October 2018
17 Reads

Impact of body mass index on CT attenuation of adrenal adenoma.

Eur J Radiol 2018 Nov 2;108:184-188. Epub 2018 Oct 2.

Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, 3-1-1, Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.

Objective: To investigate whether lipid metabolism-related factors regulate unenhanced CT attenuation in adrenal adenoma (AA).

Materials And Methods: Thirty-six patients with surgically proven AAs were enrolled in this study. The patients' underlying diseases were the following: primary aldosteronism (n = 24), Cushing's syndrome (n = 8), subclinical Cushing's syndrome (n = 3) and non-functioning AA (n = 1). Read More

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https://linkinghub.elsevier.com/retrieve/pii/S0720048X183034
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http://dx.doi.org/10.1016/j.ejrad.2018.09.033DOI Listing
November 2018
21 Reads

Ultrasound Imaging of Hepatocellular Adenoma Using the New Histology Classification.

Ultrasound Med Biol 2019 01 3;45(1):1-10. Epub 2018 Nov 3.

Department of Ultrasound, Zhongshan Hospital, Fudan University, Shanghai, China.

Hepatocellular adenoma is a rare benign liver tumor. Predisposing factors include hepatic storage diseases and some genetic conditions. A new histology-based classification has been proposed but to date, the corresponding ultrasound imaging features have not been reported. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03015629183027
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http://dx.doi.org/10.1016/j.ultrasmedbio.2018.06.015DOI Listing
January 2019
14 Reads

[Epidemiological, clinical, histological and therapeutic features of primary digestive cancers in Burkina Faso].

Bull Cancer 2018 Dec 2;105(12):1119-1125. Epub 2018 Nov 2.

CHU de Ouahigouya, service d'urologie, Ouahigouya, Burkina Faso.

Objective: To study the epidemiology and histology of primary digestive cancers in semi-urban areas in Burkina Faso.

Methods: This was a descriptive study over 5 years conducted simultaneously in 2 regional hospitals in Burkina Faso. It included all patients treated for primary digestive cancers. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00074551183027
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http://dx.doi.org/10.1016/j.bulcan.2018.09.001DOI Listing
December 2018
10 Reads

An unusual presentation of gall bladder papillomatosis in association with metachromatic leukodystrophy.

BMJ Case Rep 2018 Nov 1;2018. Epub 2018 Nov 1.

Department of Paediatric Surgery, Christian Medical College and Hospital Vellore, Vellore, Tamil Nadu, India.

A 5-year-old boy with metachromatic leukodystrophy, debilitated by spastic quadriparesis presented to us with massive ascites and respiratory distress. A subtotal cholecystectomy was performed on him from another centre for a gall bladder mass a year before he came to us. Imaging revealed a polypoidal frond-like mass arising from the gall bladder fossa which was supplied by a hypertrophied branch of the right hepatic artery. Read More

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http://dx.doi.org/10.1136/bcr-2017-224162DOI Listing
November 2018
3 Reads

Cystic degeneration of hepatic adenoma: a rare complication of hepatic adenoma.

BJR Case Rep 2018 17;4(1):20170056. Epub 2017 Nov 17.

Glasgow Royal Infirmary, Glasgow, Scotland.

This case report describes a rare complication of hepatic adenomata in a 33-year-old female. The patient initially presented with abdominal pain, and baseline imaging demonstrated several hepatic adenomas, the largest of which (approximately 8 cm) was adjacent to the inferior vena cava. Owing to the location of this adenoma, surgical/vascular intervention was deemed inappropriate. Read More

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http://www.birpublications.org/doi/10.1259/bjrcr.20170056
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http://dx.doi.org/10.1259/bjrcr.20170056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6159147PMC
November 2017
19 Reads

Diet Supplementation with Soy Protein Isolate, but Not the Isoflavone Genistein, Protects Against Alcohol-Induced Tumor Progression in DEN-Treated Male Mice.

Adv Exp Med Biol 2018;1032:115-126

Department of Pharmacology & Experimental Therapeutics, Louisiana State University Health Sciences Center, New Orleans, LA, USA.

Diethylnitrosamine-treated male mice were assigned to 4 groups: a casein-based 35% high fat ethanol liquid diet (EtOH), an EtOH diet made with soy protein isolate protein (EtOH/SOY), an EtOH liquid diet supplemented with genistein (EtOH/GEN) and a chow group. EtOH feeding, final concentration 5% (v/v), continued for 16 wks. EtOH increased incidence and multiplicity of basophilic lesions and adenomas compared to the chow group, (p < 0. Read More

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http://link.springer.com/10.1007/978-3-319-98788-0_9
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http://dx.doi.org/10.1007/978-3-319-98788-0_9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385589PMC
January 2018
6 Reads

Elective Regional Therapy Treatment for Hepatic Adenoma.

Ann Surg Oncol 2019 Jan 23;26(1):125-130. Epub 2018 Oct 23.

Department of Surgery, Division of Surgical Oncology, Medical College of Wisconsin, Milwaukee, WI, USA.

Background: Locoregional therapy treatments for hepatic adenoma (HA) are typically limited to selective hepatic arterial embolization (HAE) to control acute hemorrhage. This systematic review sought to report the utilization of HAE and ablation for non-emergent treatment of HA.

Methods: A PubMed query identified studies reporting ablation or embolization for HA patients. Read More

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http://dx.doi.org/10.1245/s10434-018-6802-1DOI Listing
January 2019
1 Read

Preliminary Report: Multiple Clusters of Proliferating Cells in Non-dysplastic Corrupted Colonic Crypts Underneath Conventional Adenomas.

Authors:
Carlos A Rubio

In Vivo 2018 Nov-Dec;32(6):1473-1475

Gastrointestinal and Liver Research Laboratory, Department of Pathology, Karolinska Institute and University Hospital Stockholm, Stockholm, Sweden

Background: The finding was recently reported of clusters of colonic crypts lined with indigenous normal epithelium displaying irregular shapes underneath the adenomatous glands of conventional (tubular or villous) adenomas. These abnormal crypts were named non-dysplastic corrupted colonic crypts (NDCs). This study explored the characteristics of cell proliferation in NDCs present in a cohort of conventional adenomas. Read More

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http://iv.iiarjournals.org/lookup/doi/10.21873/invivo.11401
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http://dx.doi.org/10.21873/invivo.11401DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365757PMC
January 2019
13 Reads

Massive hepatic adenoma response to bland embolization: A case study.

Radiol Case Rep 2019 Jan 11;14(1):48-51. Epub 2018 Oct 11.

Piedmont Hospital, Atlanta, GA 30309, USA.

Hepatic adenomas are rare, benign liver masses of rising incidence in the United States. We present a report of a 22-year-old asymptomatic female with a massive (14.2 × 11. Read More

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http://dx.doi.org/10.1016/j.radcr.2018.09.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6187088PMC
January 2019

CHL1 expression differentiates Hürthle cell carcinoma from benign Hürthle cell nodules.

J Surg Oncol 2018 Nov 12;118(6):1042-1049. Epub 2018 Oct 12.

Department of Surgery, New York Presbyterian Hospital-Weill Cornell Medical College, New York, New York.

Background And Objectives: Hürthle cell carcinoma (HCC) is an unusual and relatively rare type of differentiated thyroid cancer. Currently, cytologic analysis of fine-needle aspiration biopsy is limited in distinguishing benign Hürthle cell neoplasms from malignant ones. The aim of this study was to determine whether differences in the expression of specific genes could differentiate HCC from benign Hürthle cell nodules by evaluating differential gene expression in Hürthle cell disease. Read More

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http://doi.wiley.com/10.1002/jso.25214
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http://dx.doi.org/10.1002/jso.25214DOI Listing
November 2018
5 Reads
3.240 Impact Factor

Colonoscopy attachments for the detection of precancerous lesions during colonoscopy: A review of the literature.

World J Gastroenterol 2018 Oct;24(37):4243-4253

Hepato-gastroenterology Unit, Second Department of Internal Medicine -Propaedeutic, Research Institute and Diabetes Center, Medical School, National and Kapodistrian University of Athens, ''Attikon" University General Hospital, Athens 12462, Greece.

Although colonoscopy has been proven effective in reducing the incidence of colorectal cancer through the detection and removal of precancerous lesions, it remains an imperfect examination, as it can fail in detecting up to almost one fourth of existing adenomas. Among reasons accounting for such failures, is the inability to meticulously visualize the colonic mucosa located either proximal to haustral folds or anatomic curves, including the hepatic and splenic flexures. In order to overcome these limitations, various colonoscope attachments aiming to improve mucosal visualization have been developed. Read More

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http://www.wjgnet.com/1007-9327/full/v24/i37/4243.htm
Publisher Site
http://dx.doi.org/10.3748/wjg.v24.i37.4243DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175757PMC
October 2018
14 Reads

Underwater endoscopic mucosal resection of serrated adenomas.

Clinics (Sao Paulo) 2018 10 8;73:e339. Epub 2018 Oct 8.

Endoscopia, Fleury Medicina e Saude, Sao Paulo, SP, BR.

Objectives: Serrated polyps, which are considered to be precursors of colorectal carcinoma, include hyperplastic polyps, sessile serrated adenomas and traditional serrated adenomas. With the exception of hyperplastic polyps, all of these lesions must be removed. This study sought to examine whether underwater endoscopic mucosal resection is a safe and effective technique for treating serrated polyps. Read More

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http://dx.doi.org/10.6061/clinics/2018/e339DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152183PMC
October 2018
1 Read

Symptomatic hepatic metastasis of insulinoma 15 years after pancreatic resection.

Turk J Surg 2018 3;34(3):240-242. Epub 2018 Jan 3.

Department of Pathology, Türkiye Yüksek İhtisas Hospital, Ankara, Turkey.

Malignant insulinomas are infrequent endocrine tumors with miscellaneous clinical courses. In this report, we present a rare case of insulinoma that recurred with solitary hepatic metastasis 15 years after the initial resection of the primary tumor from the pancreas. A 20-year-old woman first presented with the symptoms of hypoglycemia in 1996. Read More

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http://dx.doi.org/10.5152/turkjsurg.2017.3276DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173605PMC
January 2018
3 Reads

Risk of hepatic neoplasms in Wolf-Hirschhorn syndrome (4p-): Four new cases and review of the literature.

Am J Med Genet A 2018 Nov 5;176(11):2389-2394. Epub 2018 Oct 5.

Division of Medical Genetics, Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, Utah.

Wolf-Hirschhorn syndrome (WHS) is a rare contiguous gene deletion disorder characterized by distinctive craniofacial features, prenatal/postnatal growth deficiency, intellectual disability, and seizures. Various malformations of internal organs are also seen. Neoplasia has not been documented as a typical feature of WHS. Read More

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http://doi.wiley.com/10.1002/ajmg.a.40469
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http://dx.doi.org/10.1002/ajmg.a.40469DOI Listing
November 2018
4 Reads

Contrast-enhanced ultrasound in the diagnosis of pediatric focal nodular hyperplasia and hepatic adenoma: interobserver reliability.

Pediatr Radiol 2019 01 28;49(1):82-90. Epub 2018 Sep 28.

Department of Radiology, Kings College Hospital, Denmark Hill, London, SE5 9RS, UK.

Background: Focal nodular hyperplasia and hepatic adenoma are rare liver tumors in which specific features on contrast-enhanced ultrasound (US) have been reported but are little known in children.

Objective: To assess the interobserver agreement in diagnosing and differentiating focal nodular hyperplasia and hepatic adenoma in children using established adult contrast-enhanced US characteristics.

Materials And Methods: Thirty children with a definite or probable diagnosis of focal nodular hyperplasia or hepatic adenoma on magnetic resonance imaging (MRI)/histology who underwent contrast-enhanced US studies were included. Read More

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http://link.springer.com/10.1007/s00247-018-4250-5
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http://dx.doi.org/10.1007/s00247-018-4250-5DOI Listing
January 2019
9 Reads