4,566 results match your criteria Henoch-Schonlein Purpura Anaphylactoid Purpura


Henoch-Schönlein Purpura in Children: An Updated Review.

Curr Pediatr Rev 2020 May 7. Epub 2020 May 7.

Pediatric Institute, Kuala Lumpur General Hospital, Kuala Lumpur. Malaysia.

Background: Henoch-Schönlein purpura (HSP) is an IgA-mediated systemic small-vessel vasculitis with a predilection for the skin, gastrointestinal tract, joints, and kidneys. It is the most common form of systemic vasculitis in children.

Objective: To familiarize physicians with the etiopathogenesis, etiology, clinical manifestations, evaluation, and management of children with Henoch-Schönlein purpura. Read More

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http://dx.doi.org/10.2174/1573396316666200508104708DOI Listing

A case of Henoch-Schönlein purpura associated with scrub typhus.

BMC Infect Dis 2020 Apr 17;20(1):286. Epub 2020 Apr 17.

Division of Infectious Diseases, Department of Internal Medicine, Inha University College of Medicine, 7-206, Shinheung-Dong, Jung-Gu, Incheon, 22332, Republic of Korea.

Background: Henoch-Schönlein purpura (HSP) may be caused by several allergens. However, to date, HSP caused by Orientia tsutsugamushi has not been reported. Here, we report an unusual rash with features of HSP caused by Orientia tsutsugamushi. Read More

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http://dx.doi.org/10.1186/s12879-020-05001-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7165380PMC

In Reply, IgA Vasculitis (Henoch-Schönlein Purpura) in Argentina: Comparison Between Pediatric and Adult Population.

Mayo Clin Proc 2020 02;95(2):424

Department of Rheumatology, Mayo Clinic, Rochester, MN.

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http://dx.doi.org/10.1016/j.mayocp.2019.11.022DOI Listing
February 2020

IgA Vasculitis (Henoch-Schönlein Purpura) in Argentina: Comparison Between Pediatric and Adult Populations.

Mayo Clin Proc 2020 02;95(2):422-424

Rheumatology Unit, Internal Medicine Department, Hospital Italiano de Buenos Aires, Ciudad Autónoma de Buenos Aires, Argentina.

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http://dx.doi.org/10.1016/j.mayocp.2019.11.023DOI Listing
February 2020

[Henoch-Shonlein purpura in adults in South Tunisia: a series of 14 cases].

Pan Afr Med J 2019 23;34:107. Epub 2019 Oct 23.

Service de Médecine Interne, CHU Hédi Chaker, Sfax, Tunisie.

Henoch-Schonlein purpura (HSP) is a small-vessel vasculitis secondary to IgA deposits. We conducted a retrospective study of 14 cases of HSP in adults based on EULAR/PRINTO/PRES classification criteria for HSP over a period of 18 years (1996 to 2014) in Department of Internal Medicine at the Hedi Chaker University Hospital, Sfax, South Tunisia. The purpose of our study was to highlight the epidemiological, clinical, therapeutic and evolutionary features of HSP in our adult patients. Read More

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http://dx.doi.org/10.11604/pamj.2019.34.107.17274DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6945384PMC
January 2020

A good response to glucocorticoid for Henoch-Schönlein purpura with abdominal pain and gastrointestinal bleeding in an adult: A CARE case report.

Medicine (Baltimore) 2020 Jan;99(1):e18602

Department of Gastroenterology, General Hospital of Northern Theater Command, Shenyang.

Rationale: Henoch-Schönlein purpura (HSP) is a small-vessel vasculitis that has been extensively studied in children, but little is known about its natural history in adults. There is no consensus regarding the treatment of glucocorticosteroids use for HSP. The efficacy of glucocorticoid for preventing from severe complications or relapse is also controversial in HSP. Read More

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http://dx.doi.org/10.1097/MD.0000000000018602DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6946351PMC
January 2020

Hemotologic Indices for Predicting Internal Organ Involvement in Henoch-Schönlein Purpura (IgA vasculitis).

J Pediatr Hematol Oncol 2020 01;42(1):e46-e49

Division of Pediatric Hematology/Oncology.

Henoch-Schönlein purpura is the most common vasculitis of childhood. This study investigated the values of hematologic indices that can help predict internal organ involvement. The study included 112 patients followed up between January 2007 and May 2017 and 81 healthy children. Read More

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http://dx.doi.org/10.1097/MPH.0000000000001571DOI Listing
January 2020

Henoch-Schönlein Nephritis Manifesting with Purpura 15 years after Diagnosis of IgA Nephropathy.

Case Rep Nephrol 2019 29;2019:1042648. Epub 2019 Oct 29.

Department of Nephrology, Hirosaki University Hospital, Hirosaki, Japan.

Henoch-Schönlein nephritis or immunoglobulin A (IgA) vasculitis is characterized by purpura, arthralgia, abdominal pain, and glomerulonephritis with glomerular IgA deposition. Notably, the presence of purpura is essential to diagnose this disease. We report the case of a patient in whom proteinuria and haematuria were detected during screening tests and he was diagnosed with IgA nephropathy at 20 years of age. Read More

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http://dx.doi.org/10.1155/2019/1042648DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6854950PMC
October 2019

Henoch-Schönlein Purpura in children: not only kidney but also lung.

Pediatr Rheumatol Online J 2019 Nov 21;17(1):75. Epub 2019 Nov 21.

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Pediatric Highly Intensive Care Unit, 20122, Milan, Italy.

Background: Henoch-Schönlein Purpura (HSP) is the most common vasculitis of childhood and affects the small blood vessels. Pulmonary involvement is a rare complication of HSP and diffuse alveolar hemorrhage (DAH) is the most frequent clinical presentation. Little is known about the real incidence of lung involvement during HSP in the pediatric age and about its diagnosis, management and outcome. Read More

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http://dx.doi.org/10.1186/s12969-019-0381-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6873759PMC
November 2019

Predicative value of urinary protein biomarkers on delayed renal involvement in children with Henoch-Schönlein purpura.

Sci China Life Sci 2019 12 20;62(12):1594-1596. Epub 2019 Nov 20.

Clinical Laboratory Center, Anhui Provincial Children's Hospital, Hefei, 230051, China.

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http://dx.doi.org/10.1007/s11427-018-9544-0DOI Listing
December 2019

Obesity is associated with Henoch-Schönlein Purpura Nephritis and development of end-stage renal disease in children.

Ren Fail 2019 Nov;41(1):1016-1020

Department of Pediatrics, Fujian Provincial Hospital, Fujian Medical University Shengli Clinical Medical College, Fuzhou, China.

To explore the association of obesity with the occurrence of Henoch-Schönlein Purpura Nephritis (HSPN) and development of end-stage renal disease (ESRD) in children with Henoch-Schönlein Purpura (HSP). This was a retrospective study of 446 pediatric patients with diagnosed HSP. All patients' demographic characteristics, clinical features, and laboratory data were collected from the electronic medical records in hospitals from January 2008 to December 2014, and the prognosis was followed up till December 2018. Read More

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http://dx.doi.org/10.1080/0886022X.2019.1685545DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882475PMC
November 2019

Henoch-Schonlein Purpura Presenting With Bilateral Solid Testicular Masses in an Adult.

Urology 2020 Feb 10;136:e26-e29. Epub 2019 Nov 10.

Department of Dermatology, University of Nebraska Medical Center, Omaha, NE. Electronic address:

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http://dx.doi.org/10.1016/j.urology.2019.10.020DOI Listing
February 2020

Adult onset of Immunoglobulin A vasculitis - A case report.

J Med Invest 2019 ;66(3.4):344-346

Department of Cardiovascular Medicine, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.

Immunoglobulin A vasculitis (IgAV), formerly known as Henoch-Schönlein purpura, primarily occurs during childhood between the ages of 3 and 15 years and is the most common form of systemic vasculitis in children ; its occurrence in adults has been rarely reported. Such low incidence could be attributable to either under-diagnosis or misdiagnosis. Thus, not only pediatricians but also physicians should be able to diagnose IgAV accurately to manage the patients appropriately and avoid its associated complications. Read More

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http://dx.doi.org/10.2152/jmi.66.344DOI Listing

[Expression of gamma-delta T cells in immune microenvironment in children with Henoch-Schönlein purpura].

Zhongguo Dang Dai Er Ke Za Zhi 2019 Oct;21(10):960-965

Ningxia Medical University, Yinchuan 750004, China.

Objective: To study the role of gamma-delta T (γδ T) cells and its subsets in the immunopathogenesis of Henoch-Schönlein purpura (HSP) in children, and to provide new ideas for the treatment of HSP in children from the aspect of γδ T cell regulation.

Methods: A total of 33 children with HSP were enrolled as the HSP group, and 21 healthy children were enrolled as the healthy control group. The percentages of γδ T cells and its subsets Vδ1 T and Vδ2 T cells among peripheral blood mononuclear cells (PBMCs) were measured, as well as the apoptosis rate of γδ T cell and plasma level of interleukin-17 (IL-17). Read More

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October 2019

[Clinical effect of double filtration plasmapheresis combined with glucocorticoid and immunosuppressant in treatment of children with severe Henoch-Schönlein purpura nephritis].

Zhongguo Dang Dai Er Ke Za Zhi 2019 Oct;21(10):955-959

Department of Pediatrics, Harrison International Peace Hospital, Hengshui, Hebei 053000, China.

Objective: To study the clinical effect and safety of double filtration plasmapheresis (DFPP) combined with double pulse therapy with methylprednisolone (MP) and cyclophosphamide (CTX) in the treatment of children with severe Henoch-Schönlein purpura nephritis (HSPN).

Methods: A total of 60 children with severe HSPN who were admitted to the hospital from January 2014 to March 2018 were enrolled and were randomly divided into an observation group and a control group (n=30 each). In addition to routine treatment, the children in the control group were given MP+CTX pulse therapy. Read More

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October 2019
7 Reads

Unusual presentation of Henoch-Schönlein purpura.

J Biol Regul Homeost Agents 2019 Sep-Oct;33(5 Suppl. 1):69-74

Department of Human Pathology in Adult and Developmental Age "Gaetano Barresi", Unit of Emergency Pediatrics, University of Messina, Policlinico "G. Martino" Messina, Italy.

Henoch Schonlein Purpura (HSP) is a systematic IgA-mediated vasculitic disease that affects the small vessels of the skin, the joints, the gastrointestinal tract and the kidneys (1). It is the most common childhood vaculitis, with an incidence estimated at 3-26 per 100,000 children, and with a male-to-female ratio of 2:1 (2-6). The 90% of patients are under 10 years of age, with a mean age of 4 years (4). Read More

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November 2019
2 Reads

Dapsone in immunoglobulin A-associated vasculitis.

Eur J Pediatr 2019 12 19;178(12):1913-1914. Epub 2019 Oct 19.

Pediatric Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

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http://dx.doi.org/10.1007/s00431-019-03472-yDOI Listing
December 2019

[Long-term effect of Tripterygium Glycosides Tablets combined with traditional Chinese medicine on adulthood fertility].

Zhongguo Zhong Yao Za Zhi 2019 Aug;44(16):3558-3561

the First Affiliated Hospital of Henan University of Chinese Medicine,Henan Children's Hospital of Integrated Traditional Chinese and Western Medicine Zhengzhou 450004,China Henan University of Chinese Medicine Zhengzhou 450046,China.

To preliminarily investigate the effect of Tripterygium Glycosides Tablets( TGT) combined with traditional Chinese medicine( TCM) on the fertility and female menstruation on persons who have took during childhood. The children with henoch-schonlein purpura( HSP) or henoch-schonlein purpura nephritis( HSPN) who treated with TGT under 18 years old and now older than 18 years old( including 18 years old) during January 1998 to December 2010 were selected in our research. The content of follow-up visit included marriage,marriage age,fertility and child health; and unmarried female patients were asked whether they had menstrual abnormalities. Read More

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http://dx.doi.org/10.19540/j.cnki.cjcmm.20190422.501DOI Listing
August 2019
2 Reads

National Trends in the Epidemiology and Resource Use for Henoch-Schönlein Purpura (IgA Vasculitis) Hospitalizations in the United States From 2006 to 2014.

Hosp Pediatr 2019 11 1;9(11):888-896. Epub 2019 Oct 1.

Section of Neonatology, Valley Children's Healthcare, Madera, California

Objectives: We examined the trends in the rate of Henoch-Schönlein purpura (HSP) hospitalizations and the associated resource use among children in the United States from 2006 through 2014.

Methods: Pediatric hospitalizations with HSP were identified by using , code 287.0 from the National Inpatient Sample. Read More

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http://dx.doi.org/10.1542/hpeds.2019-0131DOI Listing
November 2019

Efficacy of montelukast for the treatment of pediatric allergic purpura.

Medicine (Baltimore) 2019 Sep;98(39):e17239

Department of Dermatology, Affiliated Hongqi Hospital of Mudanjiang Medical University, Mudanjiang, China.

Background: This study aims to evaluate the efficacy and safety of montelukast for the treatment of patients with pediatric allergic purpura (PAP).

Methods: We will retrieve the following electronic databases from inception to the present: MEDILINE, Embase, CENTRAL, CINAHL, AMED, Chinese Biomedical Literature Database, China National Knowledge Infrastructure Database, Wanfang, and VIP database without language limitation. Two authors will carry out study selection, data extraction, and quality evaluation independently. Read More

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http://dx.doi.org/10.1097/MD.0000000000017239DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6775355PMC
September 2019
5.723 Impact Factor

Risk factors associated with IgA vasculitis with nephritis (Henoch-Schönlein purpura nephritis) progressing to unfavorable outcomes: A meta-analysis.

PLoS One 2019 1;14(10):e0223218. Epub 2019 Oct 1.

Department of Nephrology, Children's Hospital, Chongqing Medical University, Chongqing, China.

Objective: To identify risk factors associated with unfavorable outcomes in children with IgA vasculitis with nephritis (Henoch-Schőnlein purpura nephritis)(IgA-VN).

Methods: PubMed, Embase, and Web of Science databases were searched for studies, published in English through February 2019. The data were extracted to perform pooled analysis, heterogeneity testing, subgroup analysis, sensitivity analysis, and publication bias analysis. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0223218PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6772070PMC
March 2020
4 Reads

8-year-old boy • palpable purpura on the legs with arthralgia • absence of coagulopathy • upper respiratory infection • Dx?

J Fam Pract 2019 09;68(7):411;412;414

Texas A&M College of Medicine, Baylor University Medical Center, Dallas, USA.

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September 2019

Henoch-Schönlein purpura with intussusception and hematochezia in an adult: A case report.

Medicine (Baltimore) 2019 Sep;98(36):e16981

Department of Gastrointestinal Nutrition and Hernia Surgery.

Rationale: Henoch-Schönlein purpura (HSP) is a common disease in children. However, HSP with intussusception and intestinal obstruction has a low morbidity in children and is occasionally seen in adults. Herein, a rare adult case of HSP complicated with intussusception and hemafecia that was successfully treated with surgery is described. Read More

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http://dx.doi.org/10.1097/MD.0000000000016981DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739011PMC
September 2019
5 Reads
5.723 Impact Factor

Painless purple streaks on the arms and chest.

Cutis 2019 Jul;104(1):E8-E9

Department of Dermatology, Division of Pediatric Dermatology, Johns Hopkins University School of Medicine, Baltimore, USA.

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Early recognition and treatment of Henoch-Schönlein purpura in children.

Authors:
Ann Wilkinson

Nurs Child Young People 2019 Sep;31(5):36-40

Gresleydale Healthcare Centre, Derbyshire, England.

Henoch-Schönlein purpura (HSP) is characterised by a non-blanching rash, which commonly affects the lower limbs of children aged 3-15 years. It is the most common vasculitis in children. HSP often develops after an upper respiratory tract infection and is more likely to present in autumn, winter and spring. Read More

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http://dx.doi.org/10.7748/ncyp.2019.e1118DOI Listing
September 2019
2 Reads

A clinicopathological comparison between IgA nephropathy and Henoch-Schönlein purpura nephritis in children: use of the Oxford classification.

Clin Exp Nephrol 2019 Dec 29;23(12):1382-1390. Epub 2019 Aug 29.

Department of Nephrology, Beijing Children's Hospital, Capital Medical University, Beijing, 100045, China.

Background: There is controversy over whether IgA nephropathy (IgAN) and Henoch-Schönlein purpura nephritis (HSPN) are the same diseases. This study focuses on the clinicopathological comparison between HSPN and IgAN in children.

Methods: Children with IgAN and HSPN who had a diagnostic renal biopsy were enrolled. Read More

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http://dx.doi.org/10.1007/s10157-019-01777-8DOI Listing
December 2019
5 Reads

Serum levels of selected cytokines [interleukin (IL)-17A, IL-18, IL-23] and chemokines (RANTES, IP10) in the acute phase of immunoglobulin A vasculitis in children.

Rheumatol Int 2019 Nov 29;39(11):1945-1953. Epub 2019 Aug 29.

Department of Paediatrics, School of Medicine with the Division of Dentistry in Zabrze, Medical University of Silesia in Katowice, ul. 3-go Maja 13-15, 41-800, Zabrze, Poland.

The pathogenesis of the immunoglobulin A vasculitis (IgAV) is still unknown. The available data shows that interleukin (IL)-17, IL-18, IL-23, regulated on activation, normal T cell expressed and secreted (CCL 5, RANTES), and interferon (IFN)-γ-inducible protein 10 (IP10) participate in the pathogenesis of IgAV by influencing the recruitment of leukocytes to the site of inflammation. The aim of this study was to analyze the serum concentration of IL-17A, IL-18, IL-23, RANTES, and IP10 in patients with acute IgAV compared to healthy children. Read More

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http://dx.doi.org/10.1007/s00296-019-04415-4DOI Listing
November 2019
3 Reads

Traditional Chinese medicine versus regular therapy in Henoch-Schönlein purpura nephritis in children: study protocol for a randomized controlled trial.

Trials 2019 Aug 29;20(1):538. Epub 2019 Aug 29.

Pediatric Kidney Disease Center, the First Affiliated Hospital of Henan University of TCM, Zhengzhou, China.

Background: Henoch-Schönlein purpura nephritis (HSPN) is the most common secondary glomerular disease in children. Currently, the treatment for HSPN is always selected based on the Kidney Disease Improving Global Outcomes guidelines; however, this approach may lead to undertreatment, especially in patients with persistent proteinuria that does not reach nephrotic levels and/or hematuria and those with a pathological classification between grades 1 and 3 according to the International Study of Kidney Disease in Children. This study was performed to evaluate the curative effect and safety of a traditional Chinese medicine (TCM) integrated treatment program in this type of HSPN. Read More

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http://dx.doi.org/10.1186/s13063-019-3484-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6716925PMC
August 2019
3 Reads
2.117 Impact Factor

Exploration of susceptible genes associated with Henoch-Schönlein purpura by whole exome sequencing.

Adv Clin Exp Med 2019 Sep;28(9):1199-1207

Department of Medical Genetics, Institute of Pediatric Translational Medicine, Shanghai Children's Medical Center, Shanghai Jiaotong University School of Medicine, China.

Background: Henoch-Schönlein purpura (HSP) is a systemic small-vessel vasculitis caused by environmental and inherent factors. Although recent research has advanced our understanding of the role of genetic susceptibility in HSP, there are still significant gaps in our knowledge.

Objectives: In this study, we aimed to explore some susceptibility genes likely associated with HSP. Read More

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http://dx.doi.org/10.17219/acem/103800DOI Listing
September 2019
2 Reads

Serum neopterin and ischemia modified albumin levels are associated with the disease activity of adult immunoglobulin A vasculitis (Henoch-Schönlein purpura).

Int J Rheum Dis 2019 Oct 14;22(10):1920-1925. Epub 2019 Aug 14.

Department of Medical Biochemistry, University of Health Sciences, Gülhane School of Medicine, Ankara, Turkey.

Aim: The aims of the study are to investigate serum neopterin and ischemia modified albumin (IMA) levels in patients with immunoglobulin A vasculitis (IgAV) and evaluate the association of these markers with disease activity and relapse.

Method: Thirty-four consecutive adult patients (24 male and 10 female) admitted to the rheumatology clinic and met the IgAV American College of Rheumatology (ACR) criteria were enrolled in this cross-sectional study. Demographic and clinical features of IgAV and a control group were recorded into a predefined protocol. Read More

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http://dx.doi.org/10.1111/1756-185X.13673DOI Listing
October 2019
2 Reads

Extrarenal Immune-Mediated Disorders Linked with Acute Poststreptococcal Glomerulonephritis: a Systematic Review.

Clin Rev Allergy Immunol 2019 Oct;57(2):294-302

Pediatric Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

Streptococcus A infections have been associated with immune-mediated sequelae including acute glomerulonephritis, acute rheumatic fever, thrombocytopenia, hemolytic anemia, Henoch-Schönlein purpura, arthritis, uveitis, guttate psoriasis, and erythema nodosum. Available reviews do not report the occurrence of acute poststreptococcal glomerulonephritis in association with one of the mentioned conditions. We performed a systematic review of the literature on extrarenal immune-mediated disorders associated with acute poststreptococcal glomerulonephritis. Read More

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http://dx.doi.org/10.1007/s12016-019-08761-wDOI Listing
October 2019
9 Reads

The Clinicopathological Characteristics of Henoch-Schönlein Purpura Nephritis with Presentation of Nephrotic Syndrome.

Kidney Blood Press Res 2019 6;44(4):754-764. Epub 2019 Aug 6.

Division of Nephrology, Department of Medicine, West China Hospital, Sichuan University, Chengdu, China,

Background: Henoch-Schönlein purpura nephritis (HSPN) is a common vasculitis involving the kidneys, with a lower incidence in adults. Meanwhile, nephrotic syndrome (NS) can appear in HSPN. However, the clinicopathological features and renal outcome of adult-onset HSPN presenting with NS (NS-HSPN) have not been well clarified. Read More

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http://dx.doi.org/10.1159/000501459DOI Listing
January 2020
8 Reads

Clinical significance of ANCA positivity in patients with IgA vasculitis: a retrospective monocentric study.

Rheumatol Int 2019 Nov 1;39(11):1927-1936. Epub 2019 Aug 1.

Division of Rheumatology, Department of Internal Medicine, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea.

We assessed the detection rate of antineutrophil cytoplasmic antibody (ANCA) and investigated the clinical significance of ANCA positivity at diagnosis in patients with IgA vasculitis (Henoch-Schönlein purpura). We retrospectively reviewed their medical records of 86 IgA vasculitis patients. We divided IgA vasculitis patients based on ANCA positivity and compared variables at diagnosis and poor outcomes and medication during follow-up between the two groups. Read More

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http://dx.doi.org/10.1007/s00296-019-04397-3DOI Listing
November 2019
3 Reads

Posterior reversible encephalopathy syndrome and intracerebral hemorrhage in an adult patient with Henoch-Schönlein purpura.

Indian J Dermatol Venereol Leprol 2019 Sep-Oct;85(5):502-505

Department of Dermatology, 306 Hospital of PLA, Beijing, China.

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http://dx.doi.org/10.4103/ijdvl.IJDVL_681_18DOI Listing
February 2020
1 Read

Role of p300 in the pathogenesis of Henoch-Schonlein purpura nephritis and as a new target of glucocorticoid therapy in mice.

Chin Med J (Engl) 2019 Aug;132(16):1942-1950

Department of Pediatrics, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning 110001, China.

Background: Henoch-Schonlein purpura nephritis (HSPN) is a very common secondary kidney disease of childhood. Its pathogenesis and the treatment mechanism of glucocorticoid have not been fully elucidated. The aim of this study was to determine the relationship between p300 and the pathogenesis, glucocorticoid therapy in mice with HSPN, respectively. Read More

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http://dx.doi.org/10.1097/CM9.0000000000000380DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708694PMC
August 2019
3 Reads
1.016 Impact Factor

50 Years Ago in TheJournal ofPediatrics: Anaphylactoid Purpura: Streptococcal Antibody Titers and β-Globulin Levels.

Authors:
Philip J Hashkes

J Pediatr 2019 Aug;211:111

Pediatric Rheumatology Unit, Shaare Zedek Medical Center, Jerusalem, Israel.

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http://dx.doi.org/10.1016/j.jpeds.2019.01.029DOI Listing
August 2019
2 Reads

Association of the infectious triggers with childhood Henoch-Schonlein purpura in Anhui province, China.

J Infect Public Health 2020 Jan 20;13(1):110-117. Epub 2019 Jul 20.

Department of Pediatrics, The First Affiliated Hospital of Anhui Medical University, Hefei, China. Electronic address:

Background: Although the specific etiology of Henoch-Schonlein purpura (HSP) is still unknown, several kinds of infectious triggers have been proved to participate in its pathogenesis. The objectives of present study were to analyze the association of the infectious triggers with childhood HSP in Anhui province, China.

Methods: 1200 HSP children were recruited from January 2015 to December 2017. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S18760341193023
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http://dx.doi.org/10.1016/j.jiph.2019.07.004DOI Listing
January 2020
8 Reads

Seizures, renal failure and acute respiratory failure: not your typical case of Henoch-Schonlein purpura.

BMJ Case Rep 2019 Jul 17;12(7). Epub 2019 Jul 17.

Department of Medicine, Deaconess Health System, Evansville, Indiana, USA.

A 30-year-old Caucasian woman with no prior medical history presented with pedal oedema, arthralgias and abdominal pain with diarrhoea, following a respiratory infection. She had mild abdominal tenderness along with a purpuric rash on the extremities and was anaemic. Following initial workup for anaemia and rash, her condition deteriorated with renal impairment, respiratory failure and seizures necessitating ventilatory support, dialysis and steroids. Read More

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http://dx.doi.org/10.1136/bcr-2019-229939DOI Listing
July 2019
4 Reads

Less IgA deposits with more severe disease: the immunoclinical paradox in Henoch-Schönlein Purpura with MEFV mutations.

Clin Rheumatol 2019 11 17;38(11):3311-3313. Epub 2019 Jul 17.

Department of Nephrology, Ankara University, Ankara, Turkey.

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http://dx.doi.org/10.1007/s10067-019-04677-0DOI Listing
November 2019
2 Reads

[Analysis of relevant risk factors to Henoch-Schönlein purpura in Tibetan children].

Zhonghua Wei Zhong Bing Ji Jiu Yi Xue 2019 Jun;31(6):742-745

Department of Pediatric Intensive Care Unit, Anhui Provincial Children's Hospital, Hefei 230051, Anhui, China. Xu Yuanyuan is working on the Department of Pediatrics, Shannan People's Hospital of Tibet Autonomous Region, Shannan 856000, Tibet Autonomous Region, China. Corresponding author: Xu Yuanyuan, Email:

Objective: To analyze probable risk factors to Henoch-Schönlein purpura (HSP) in Tibetan children so as to bring evidences for correct identification of high-risk children in plateau areas.

Methods: 140 high-altitude Tibetan children with HSP admitted to Shannan People's Hospital of Tibet Autonomous Region from October 2015 to October 2018 were enrolled, and 140 high-altitude Tibetan healthy children and 140 plain area HSP children were selected as the control. Gender, age, family history, allergy, past history (rheumatic disease, autoimmune disease, asthma), clinical phenotype, biochemical markers (antibody positive rate, platelet count and hemoglobin), clinical efficacy and recurrence were retrospective analyzed. Read More

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http://dx.doi.org/10.3760/cma.j.issn.2095-4352.2019.06.016DOI Listing
June 2019
8 Reads

[Cutaneous alterations in vasculitides : Part 2: Special aspects of diseases of large, medium and small vessels].

Internist (Berl) 2019 Aug;60(8):805-813

Universitätsklinikum Halle (Saale), Universitätsklinik und Poliklinik für Dermatologie und Venerologie, Martin-Luther-Universität Halle-Wittenberg, Ernst-Grube-Str. 40, 06120, Halle (Saale), Deutschland.

Cutaneous vasculitides present with typical clinical signs depending on the size and distribution of the affected vessels. Since there are no large vessels in the skin, giant cell arteritis and Takayasu's arteritis only rarely lead to cutaneous symptoms. The classical systemic polyarteritis nodosa (PAN) is very rare. Read More

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http://dx.doi.org/10.1007/s00108-019-0642-3DOI Listing
August 2019
5 Reads

Crescent lesions are not a predictive factor in adult-onset Henoch-Schönlein purpura nephritis.

Clin Exp Med 2019 Nov 10;19(4):449-456. Epub 2019 Jul 10.

Division of Nephrology, Department of Medicine, West China Hosiptal, Sichuan University, Chengdu, Sichuan, China.

Henoch-Schönlein purpura nephritis (HSPN) is a common secondary glomerulonephritis, and its prognosis mainly depends on the severity of renal impairment. To date, the significance of crescent lesions in adult-onset HSPN is still unclear. Therefore, the purpose of this research was to assess whether crescents could predict the renal outcomes in adult HSPN patients. Read More

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http://dx.doi.org/10.1007/s10238-019-00567-6DOI Listing
November 2019
2 Reads

Henoch-Schönlein purpura nephritis associated with monoclonal gammopathy of renal significance: a case report.

Braz J Med Biol Res 2019 10;52(7):e8222. Epub 2019 Jul 10.

Department of Nephrology, Gansu Provincial Hospital, Lanzhou, Gansu, China.

Monoclonal gammopathy of renal significance (MGRS) can present with different morphologic features and lead to kidney failure. The Henoch-Schönlein purpura nephritis (HSPN) that cannot be relieved by treatment with glucocorticoid and immunosuppressive agents suggests the presence of monoclonal gammopathy in adult patients. The present study reports on a single case of HSPN associated with IgA-κMGRS. Read More

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http://dx.doi.org/10.1590/1414-431X20198222DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694773PMC
September 2019
6 Reads

[Cutaneous alterations in vasculitides : Part 1: Nomenclature, classification and correlation between clinical signs and histological features].

Internist (Berl) 2019 Aug;60(8):799-804

Universitätsklinikum Halle (Saale), Universitätsklinik und Poliklinik für Dermatologie und Venerologie, Martin-Luther-Universität Halle-Wittenberg, Ernst-Grube-Str. 40, 06120, Halle (Saale), Deutschland.

The skin is one of the organs most commonly affected by vasculitis and the only one that is open to direct inspection. Cutaneous vasculitis can be part of a systemic vasculitis, a variant restricted to the skin (e.g. Read More

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http://dx.doi.org/10.1007/s00108-019-0641-4DOI Listing
August 2019
1 Read

Serum level of advanced oxidation protein products (AOPPs) in patients with Henoch-Schonlein purpura and its relationship with aberrant glycosylation of IgA1 and Cosmc mRNA expression.

Int J Dermatol 2019 Sep 27;58(9):1092-1097. Epub 2019 Jun 27.

Dermatovenerological Department, The Second Hospital of HeBei Medical University, Shijiazhuang, HeBei Province, China.

Background: Henoch-Schonlein purpura (HSP) is a systemic small vessel vasculitis that is mainly caused by IgA1-type immune complex deposition. Advanced oxidation protein products (AOPPs) are specific markers of protein oxidation.

Objective: To explore the role of AOPPs in the pathogenesis of HSP. Read More

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http://dx.doi.org/10.1111/ijd.14550DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6852516PMC
September 2019
8 Reads

Indications and efficiency of dapsone in IgA vasculitis (Henoch-Schonlein purpura): case series and a review of the literature.

Eur J Pediatr 2019 Aug 22;178(8):1275-1281. Epub 2019 Jun 22.

Department of Pediatrics, Hôpital Civil Marie Curie, CHU of Charleroi, 140 Chaussée de Bruxelles, 6042, Charleroi (Lodelinsart), Belgium.

Immunoglobulin A (IgA) vasculitis (Henoch-Schonlein purpura (HSP)) is the most common vasculitis in children. It is characterized by purpuric rash, arthritis, gastrointestinal, and/or renal involvement. Spontaneous resolution is the typical outcome. Read More

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http://dx.doi.org/10.1007/s00431-019-03409-5DOI Listing
August 2019
17 Reads

Cutaneous small-vessel vasculitis following hysterosalpingo-foam sonography (HyFoSy).

Ultrasound Obstet Gynecol 2019 Dec;54(6):831-834

SEMEAR Fertilidade, Reproductive Medicine, Ribeirão Preto, Brazil.

We present a case of diffuse skin immune reaction, diagnosed as cutaneous small-vessel vasculitis, following assessment of tubal patency by contrast ultrasound, which appears to be the first reported case of hypersensitivity reaction to sonographic tubal patency testing, based on a literature search. A 32-year-old woman presented with non-thrombocytopenic palpable purpura the day after assessment of tubal patency by two-/three-dimensional hysterosalpingo-foam sonography (HyFoSy) using ExEm® Foam. During real-time ultrasound, the observer identified flow in only the right tube when using saline with air as contrast medium; however, the same observer identified flow in both tubes after injecting ExEm Foam and the woman left the clinic without any complications. Read More

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http://dx.doi.org/10.1002/uog.20372DOI Listing
December 2019
16 Reads

Changes in clinical features in Henoch-Schönlein purpura during three decades: an observational study at a single hospital in Korea.

Clin Rheumatol 2019 Oct 8;38(10):2811-2818. Epub 2019 Jun 8.

Departments of Pediatrics, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.

Objective: It is unknown whether epidemiological or clinical characteristics of Henoch-Schönlein purpura (HSP) have changed over time. This study aimed at evaluating the epidemiological and clinical changes of HSP during 3 decades.

Methods: We retrospectively analyzed the data of 515 children with HSP (0-15 years of age) between 1987 and 2015. Read More

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http://dx.doi.org/10.1007/s10067-019-04628-9DOI Listing
October 2019
8 Reads

[Evaluation and Comparison of Thromboelastography and Conventional Coagulation Tests for Blood Coagulation Function in Children with Henoch-Schönlein Purpura].

Zhongguo Shi Yan Xue Ye Xue Za Zhi 2019 Jun;27(3):877-886

First Department of Integrated Medical Ward, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing 100045, China,E-mail:

Objective: To evaluate the coagulation function of children with Henoch-Schönlein purpura (HSP) by thromboelastography (TEG) and conventional coagulation tests (CCTs), and to explore the correlation and consistency of the 2 test methods.

Methods: A total of 468 children with HSP were selected from January 2017 to December 2017 in Beijing Children's Hospital, Capital Medical University. The TEG and CCTs data were analyzed to evaluate coagulation function of children with HSP, meanwhile, the coagulation results were analysed the superiority of the 2 test methods was compared by Pearson correlation and Kappa consistency analysis. Read More

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http://dx.doi.org/10.19746/j.cnki.issn.1009-2137.2019.03.039DOI Listing
June 2019
21 Reads

[Evaluation and Comparison of Thromboelastography and Conventional Coagulation Tests for Blood Coagulation Function in Children with Henoch-Schönlein Purpura].

Zhongguo Shi Yan Xue Ye Xue Za Zhi 2019 Jun;27(3):850-854

Department of Hematology, Quanzhou City First Hospital, Affiliated to Fujian Medical University, Quanzhou 362000, Fujian Province, China.

Objective: To investigate the efficacy of disease control, survival time and safely in treatment of newly diagnosed multiple mycloma patients with different dose of tenalidomide regimens.

Methods: The clinical data of 116 patients with multiple myeloma from June 2011 to June 2015 were collected and analyzed retrospectively. According to doses of used lenalidomide based on dexamethasone plus lenalidomide regimen 116 patients were divided into 2 groups: conventional dose group (58 cases) and low dose group (58 cases). Read More

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http://dx.doi.org/10.19746/j.cnki.issn.1009-2137.2019.03.034DOI Listing
June 2019
20 Reads