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    4196 results match your criteria Henoch-Schonlein Purpura Anaphylactoid Purpura

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    Henoch-Schönlein purpura as a rare cause of an acute abdomen.
    Ann R Coll Surg Engl 2017 Feb 4;99(2):e88-e90. Epub 2017 Jan 4.
    Lancashire Teaching Hospitals NHS Foundation Trust , UK.
    A 52-year-old man presented with a purpuric rash affecting his legs and hypertension. He was diagnosed with Henoch-Schönlein purpura and discharged with non-steroidal anti-inflammatory drugs. Three weeks later, he presented again with loss of appetite and vomiting before developing abdominal pain with pyrexia of 38. Read More

    Staphylococcus Infection-Associated GN - Spectrum of IgA Staining and Prevalence of ANCA in a Single-Center Cohort.
    Clin J Am Soc Nephrol 2017 Jan 7;12(1):39-49. Epub 2016 Nov 7.
    Department of Pathology, and.
    Background And Objectives: Staphylococcus infection-associated GN (SAGN) is a well recognized disease entity, particularly because of the frequent IgA-dominant glomerular immunoglobulin staining on kidney biopsy. Biopsy features can resemble two other disease entities - primary IgA nephropathy and Henoch-Schönlein purpura nephritis - posing a diagnostic pitfall. This is clinically relevant because of the crucial difference in the therapeutic approach. Read More

    Histopathological and immunological changes during the acute and recovery phase in Henoch-Schönlein purpura rabbit model.
    Arch Dermatol Res 2017 Jan 21;309(1):21-30. Epub 2016 Oct 21.
    Key Laboratory of Human Diseases Comparative Medicine, Ministry of Health, Beijing, People's Republic of China.
    Henoch-Schönlein purpura (HSP) is a systemic vasculitis mediated by autologous immune complex. Animal models of HSP are scarce. Here, we describe the characteristics of HSP rabbit model in the acute and recovery phase. Read More

    [Henoch-Schönlein purpura in a cocaine consumer man with HIV infection and ANCA-p positivity].
    Medicina (B Aires) 2016;76(4):245-8
    Centro Sanatorio Delta, Rosario, Santa Fe, Argentina.
    The Henoch-Schönlein purpura (HSP) is a small vessel vasculitis with IgA immune complex deposition. The presentation in adults is rare and severe. Reported cases of HSP in patients infected with HIV are scarce. Read More

    Henoch-Schönlein purpura associated with Strongyloides stercoralis infection.
    Vojnosanit Pregl 2016 May;73(5):491-5
    Introduction: Henoch-Schönlein purpura (HSP) is a small blood vessel vasculitis, which usually manifests during childhood. The exact cause of the disease is unknown.

    Case Report: We reported a 14-year-old girl who had been admitted to our clinic due to the appearance of red macules on her extremities and face, vomiting, and pain in the abdomen and joints. Read More

    Relapses in patients with Henoch-Schönlein purpura: Analysis of 417 patients from a single center.
    Medicine (Baltimore) 2016 Jul;95(28):e4217
    aDivision of Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, University of Cantabria bDivision of Internal Medicine, Hospital Universitario Marqués de Valdecilla, IDIVAL, University of Cantabria cDivision of Pathology, Hospital Universitario Marqués de Valdecilla, IDIVAL, University of Cantabria dDivision of Pediatrics, Hospital Universitario Marqués de Valdecilla, IDIVAL, University of Cantabria eDivision of Dermatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, University of Cantabria, Santander, Spain.
    To further investigate into the relapses of Henoch-Schönlein purpura (HSP), we analyzed the frequency, clinical features, and predictors of relapses in series of 417 unselected patients from a single center. After a median follow-up of 12 (interquartile range [IQR]: 2-38) years, almost one-third of the 417 patients (n = 133; 32%; 85 men/48 women) had experienced at least 1 relapse. At the time of disease diagnosis, patients who later experienced relapses had less commonly infections than those who never suffered flares (30. Read More

    [Association of Cosmc gene mutation with susceptibility to Henoch-Schönlein purpura in children].
    Zhongguo Dang Dai Er Ke Za Zhi 2016 Jul;18(7):625-9
    Department of Rheumatology, Shanghai Children's Medical Center Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai 200127, China.
    Objective: To investigate the presence of Cosmc gene mutation in children with Henoch-Schönlein purpura (HSP) and the association between Cosmc gene mutation and the susceptibility to HSP.

    Mesults: Eighty-four children who were diagnosed with HSP between March 2014 and December 2015 were selected as the HSP group. Fifty-eight healthy volunteers matched for age and sex were enrolled as the control group. Read More

    [Abdominal symptoms necessitating surgical intervention as the initial presentation of Henoch-Schönlein purpura in children - case reports].
    Pol Merkur Lekarski 2016 Jun;40(240):377-9
    Department of Pediatrics and Nephrology, Medical University of Warsaw.
    Unlabelled: Henoch-Schönlein purpura (HSP) is the most common pediatric autoimmune vasculitis. Gastrointestinal symptoms of HSP including abdominal pain, diarrhea, and vomiting may precede skin changes by several days. We present diagnostic challenges in two adolescents with HSP and severe abdominal symptoms necessitating surgical intervention before the development of skin changes. Read More

    Henoch-Schönlein without Purpura: A Case Report and Review Literature.
    J Med Assoc Thai 2016 Apr;99(4):441-5
    Henoch-Schönlein purpura (HSP) is a multi-organ vasculitis involving skin, joints, gastrointestinal tract, and kidneys. The present study reported a 5-year-old boy presenting with intense abdominal pain, bloody diarrhea, and protein-losing enteropathy. Investigations for infectious enteritis were negative. Read More

    Azathioprine therapy for steroid-resistant Henoch-Schönlein purpura: a report of 6 cases.
    Pediatr Rheumatol Online J 2016 Jun 23;14(1):37. Epub 2016 Jun 23.
    Department of Pediatrics, Division of Rheumatology, Washington University School of Medicine, One Children's Place, Campus Box 8116, St. Louis, MO, 63110, USA.
    Background: A small percentage of children with Henoch-Schönlein purpura (HSP) develop a chronic form of the disease that often requires prolonged corticosteroid therapy. Disease modifying anti-rheumatic agents (DMARDs) or biologics have been successfully used to treat those refractory cases. Azathioprine is a DMARD that has been reported to be effective in HSP nephritis and in adult cutaneous leukocytoclastic vasculitis, a condition with cutaneous histology similar to HSP. Read More

    [Significance of detection of biomarker fecal bile acids in the diagnosis and treatment of childhood Henoch-Schönlein purpura].
    Zhongguo Dang Dai Er Ke Za Zhi 2016 Jun;18(6):517-21
    Department of Pediatrics, First Affiliated Hospital of Kunming Medical University, Kunming 650032, China.
    Objective: To investigate the changes and clinical significance of biomarker fecal bile acids (BA) in children with Henoch-Schönlein purpura (HSP).

    Methods: Nineteen children with HSP and twenty-seven healthy children were enrolled in this study. The stool samples were obtained at the acute and remission phases. Read More

    Association study between matrix metalloproteinase-9 gene (MMP9) polymorphisms and the risk of Henoch-Schönlein purpura in children.
    Genet Mol Res 2016 Jun 3;15(2). Epub 2016 Jun 3.
    Department of Gastroenterology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
    Henoch-Schönlein purpura nephritis (HSPN), the most serious long-term complication of Henoch-Schönlein purpura, is one of the most common renal diseases in children. Matrix metalloproteinase-9 (MMP-9) is implicated in the pathogenesis of renal diseases. Genomic DNA was isolated from the venous blood leukocytes of 220 unrelated patients with HSPN and 205 unrelated healthy individuals. Read More

    Fludeoxyglucose positron emission tomography-computed tomography scan showing polyarthritis in a patient with an atypical presentation of Henoch-Schönlein vasculitis without clinical signs of arthritis: a case report.
    J Med Case Rep 2016 Jun 2;10(1):159. Epub 2016 Jun 2.
    Department of Radiology and Nuclear Medicine, Radboud University Medical Centre, PO Box 9101, 6500 HB, Nijmegen, The Netherlands.
    Background: Henoch-Schönlein vasculitis is the most common systemic vasculitis in children. Arthritis or arthralgia occurs in 80 % of patients. We believe this to be the first case report to describe the finding of polyarthritis in a fludeoxyglucose positron emission tomography-computed tomography scan in a patient with Henoch-Schönlein vasculitis without clinical signs of arthritis. Read More

    HLA-DRB1 in Henoch-Schönlein purpura: A susceptibility study from North India.
    Hum Immunol 2016 Jul 13;77(7):555-8. Epub 2016 May 13.
    Department of Pediatrics, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
    Etiology of Henoch-Schönlein purpura (HSP) a small vessel vasculitis remains elusive. Susceptibility may be conferred by major histocompatibility complex. There are limited reports on the association of human leucocyte antigens (HLA) and HSP. Read More

    HENOCH-SCHONLEIN PURPURA IN CHILDHOOD A FIFTEEN-YEAR EXPERIENCE AT A TERTIARY HOSPITAL.
    J Med Liban 2016 Jan-Mar;64(1):13-7
    Objective: To examine the epidemiological and clinical characteristics of children diagnosed with Henoch Sch6nlein purpura (HSP) and to compare them with other areas in the world.

    Methods: The medical records of children with HSP were retrospectively reviewed at the Jordan University Hospital between the years 1998 and 2012. The clinical and demographical features, laboratory tests, management and outcome were assessed. Read More

    Petechial rash in children: a clinical dilemma.
    Emerg Nurse 2016 May;24(2):27-35; quiz 37
    Torbay Hospital, Torquay.
    Children with a petechial rash commonly present to emergency departments. The rash can be associated with serious illnesses, such as invasive meningococcal disease (IMD), but is usually associated with less severe conditions. This article discusses the common and important causes of petechial rash, including IMD, viral illnesses, trauma, Henoch-Schönlein purpura and idiopathic thrombocytopenic purpura. Read More

    Nephrology Update: Glomerular Disease in Children.
    FP Essent 2016 May;444:30-40; quiz 41-3
    Department of Pediatrics Case Western Reserve University School of Medicine, 11100 Euclid Ave, Cleveland, OH 44106.
    Although kidney disease is much less common in children than in adults, clinicians must remain alert for the renal conditions that occur in this population because prompt diagnosis and management are essential. Acute postinfectious glomerulonephritis occurs as an uncommon sequela of streptococcal and other infections. Management is focused on providing supportive measures, including management of fluid-electrolyte imbalance and hypertension, until the patient recovers. Read More

    Treatment Outcomes in Children with Henoch-Schönlein Nephritis.
    Adv Exp Med Biol 2016 ;912:65-72
    Department of Pediatrics and Nephrology, Medical University of Warsaw, 63A Żwirki i Wigury St, 02-091, Warsaw, Poland.
    The aim of the present study was to quantify the effects of treatment of children with Henoch-Schönlein nephritis (HSN) evaluated on the basis of kidney biopsy findings. Data were analyzed from 32 patients with HSN (mean age 9.3 ± 3. Read More

    [Protective Effect of Total Flavones of Bidens pilosa L. on IgA1 Induced Injury of HUVECs in Henoch-Schönlein Purpura Children Patients].
    Zhongguo Zhong Xi Yi Jie He Za Zhi 2016 Feb;36(2):183-7
    Objective: To explore the protective effect and mechanism of total flavones of Bidens pilosa L. (TFB) on IgA1 induced injury of venous endothelial cells in Henoch-Schönlein purpura (HSP) children patients. METHODS Human umbilical venous endothelial cells (HUVECs) were taken as subject. Read More

    Henoch-Schönlein purpura complicated by acalculous cholecystitis and intussusception, and following recurrence with appendicitis.
    Paediatr Int Child Health 2016 May 29;36(2):157-9. Epub 2016 Jan 29.
    c Departments of Pediatrics.
    Henoch-Schönlein purpura (HSP) is the most common childhood systemic vasculitis. Gastro-intestinal involvement occurs in two-thirds of patients. The characteristic skin lesions generally precede abdominal symptoms or present concurrently. Read More

    The Optimal Cut-Off Value of Neutrophil-to-Lymphocyte Ratio for Predicting Prognosis in Adult Patients with Henoch-Schönlein Purpura.
    PLoS One 2016 13;11(4):e0153238. Epub 2016 Apr 13.
    Department of Internal Medicine, Hanyang University Guri Hospital, Hanyang University College of Medicine, Guri, Korea.
    Background: The development of gastrointestinal (GI) bleeding and end-stage renal disease (ESRD) can be a concern in the management of Henoch-Schönlein purpura (HSP). We aimed to evaluate whether the neutrophil-to-lymphocyte ratio (NLR) is associated with the prognosis of adult patients with HSP.

    Methods: Clinical data including the NLR of adult patients with HSP were retrospectively analyzed. Read More

    Skin Rash and Microscopic Hematuria in a 10-Year-Old Caucasian Male.
    Lab Med 2016 May;47(2):158-62
    Department of Pathology, University of Texas Medical Branch-Galveston, Galveston, Texas
    Objective: Henoch-Schonlein purpura (HSP) is an acute, systemic, vasculitis with IgA-dominant immune deposits. With the emphasis on educational value of HSP, which is the most common form of vasculitis in children, we report an actual case from a 10-year-old boy.

    Method: The patient presented with the chief complaint of a skin rash. Read More

    Autoimmune progesterone dermatitis: Case report with history of urticaria, petechiae and palpable pinpoint purpura triggered by medical abortion.
    S Afr Med J 2016 Mar 17;106(4):48-50. Epub 2016 Mar 17.
    Anatomy and Histopathology, Medical Biosciences Department, University of the Western Cape, Cape Town; Mbeya Referral Hospital, Ministry of Health and Social Welfare, Mbeya, Tanzania.
    Autoimmune progesterone dermatitis (APD) is a rare autoimmune response to raised endogenous progesterone levels that occur during the luteal phase of the menstrual cycle. Cutaneous, mucosal lesions and other systemic manifestations develop cyclically during the luteal phase of the menstrual cycle when progesterone levels are elevated. APD symptoms usually start 3 - 10 days before menstruation and resolve 1 - 2 days after menstruation ceases. Read More

    A Lower Proportion of Regulatory B Cells in Patients with Henoch-Schoenlein Purpura Nephritis.
    PLoS One 2016 31;11(3):e0152368. Epub 2016 Mar 31.
    Genetic Diagnosis Center, The First Hospital of Jilin University, Changchun, China.
    Background: Henoch-Schoenlein purpura is the one of most common types of systemic vasculitis that involves impaired renal function and Henoch-Schoenlein purpura nephritis (HSPN). The diagnosis of this condition is largely based on immunohistologic detection of immunoglobulin A1-containing immune complex in the glomerular deposits of mesangium. Despite clinical advances, the etiopathogenesis of HSPN is still largely unknown. Read More

    Henoch-Schönlein purpura with joint involvement: Analysis of 71 cases.
    Pediatr Rheumatol Online J 2016 Mar 31;14(1):20. Epub 2016 Mar 31.
    Dongying Hospital of Shandong Provincial Hospital, Dongying, Shandong province, 257091, China.
    Background: Although joint involvement is the second most common clinical manifestation after skin involvement in patients with Henoch-Schönlein purpura (HSP), it has not been well characterized. The aim of this study was to profile the clinical characteristics and identify the potential risk factors for kidney damage in HSP patients having joint involvement.

    Methods: We retrospectively reviewed 71 cases of HSP patients with joint involvement who attended our hospital between January 2010 and March 2012 and analyzed their epidemiological profile, clinical characteristics, follow-up findings (up to three years) and overall prognosis. Read More

    [Relationship of cystatin C, fibrinogen, and 24-hour urinary protein with renal pathological grade in children with Henoch-Schönlein purpura nephritis].
    Zhongguo Dang Dai Er Ke Za Zhi 2016 Mar;18(3):233-7
    Graduate School, Xinxiang Medical University, Xinxiang, Henan 453003, China.
    Objective: To study the relationship of cystatin C (CysC), fibrinogen (Fbg), and 24-hour urinary protein with renal pathological grade in children with Henoch-Schönlein purpura nephritis (HSPN), and to explore their values.

    Methods: The clinical data of 48 children diagnosed with HSPN by renal biopsy from January 2011 to January 2015 were reviewed. According to renal pathological grading, in the 48 children with HSPN, 12 had stage IIa or lower, 12 stage IIb, 17 stage IIIa, and 7 stage IIIb or higher. Read More

    Terminal Ileitis as a Feature of Henoch-Schönlein Purpura Masquerading as Crohn Disease in Adults.
    J Clin Rheumatol 2016 Mar;22(2):82-5
    From the *Department of Pediatrics, Penn State Hershey Children's Hospital; and †Department of Medicine, Penn State Milton S. Hershey Medical Center, Hershey, PA.
    Henoch-Schönlein purpura (HSP), more recently termed immunoglobulin A (IgA) vasculitis, is a systemic small-vessel vasculitis characterized by perivascular IgA deposition. This disease manifests clinically as palpable purpura, arthralgia, gastrointestinal symptoms, and renal dysfunction. Although ileitis can be seen in HSP, terminal ileitis is virtually pathognomonic for Crohn disease. Read More

    Familial Henoch-Schönlein Syndrome.
    J Clin Rheumatol 2016 Mar;22(2):80-1
    From the *Pediatric Department, Southern Switzerland, Bellinzona, Switzerland; and † Pediatric Emergency Department, Foundation IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy.
    Little attention has been so far paid to familial cases of Henoch-Schönlein syndrome. We performed a search of the Medical Subject Headings terms (Henoch or Schönlein OR anaphylactoid purpura OR IgA nephropathy OR Berger nephropathy) AND (family OR familial). We identified no more than 19 reports including 47 families with a total of 100 affected cases: their ages ranged from 1. Read More

    [VASCULITIDES IN CHILDHOOD: A RETROSPECTIVE STUDY IN A PERIOD FROM 2002 TO 2012 AT THE DEPARTMENT OF PAEDIATRICS, UNIVERSITY HOSPITAL CENTRE ZAGREB].
    Reumatizam 2015 ;62(2):6-10
    The aim of our study was to analyze clinical features, laboratory findings, treatment, course and outcome of different types of vasculitis in children. All children aged up to 18 years that have been diagnosed with a vasculitis disorder from 2002. to 2012. Read More

    Interleukin 1 beta (IL1ß) rs16944 genetic variant as a genetic marker of severe renal manifestations and renal sequelae in Henoch-Schönlein purpura.
    Clin Exp Rheumatol 2016 May-Jun;34(3 Suppl 97):S84-8. Epub 2016 Feb 1.
    Epidemiology, Genetics & Atherosclerosis Res.Group, Systemic Inflammatory Diseases, IDIVAL; School of Medicine, Univ.of Cantabria, Santander, Spain; and Cardiovascular Pathophysiology & Genomics Research, Univ.of Witwatersrand, Johannesburg, South Africa.
    Objectives: Data from a small series suggested that the Interleukin 1 beta (IL1ß) rs16944 polymorphism may be associated with severe renal involvement and persistent renal damage (renal sequelae) in Henoch-Schönlein purpura (HSP). To confirm this association, we assessed the largest cohort of Caucasian HSP patients ever considered for genetic studies.

    Methods: 338 Spanish HSP patients and 635 sex and ethnically matched controls were recruited in this study. Read More

    Late-onset IgA vasculitis in adult patients exhibits distinct clinical characteristics and outcomes.
    Clin Exp Rheumatol 2016 May-Jun;34(3 Suppl 97):S77-83. Epub 2016 Jan 26.
    Division of Rheumatology, Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
    Objectives: The aim of this study was to determine whether adult IgA vasculitis patients who developed the disease at an older age differ from early-onset patients in terms of clinical features and outcomes.

    Methods: All consecutive adult patients who were diagnosed with IgA vasculitis between January 1997 and December 2014 were reviewed retrospectively. Patients who developed the disease at an older age (≥60 years; late-onset) were compared with those with an earlier onset of disease (<60 years; early-onset). Read More

    Atopic Dermatitis and Association of Risk for Henoch-Schönlein Purpura (IgA Vasculitis) and Renal Involvement Among Children: Results From a Population-Based Cohort Study in Taiwan.
    Medicine (Baltimore) 2016 Jan;95(3):e2586
    From the Children's Hospital (C-CW, A-CC), Management Office for Health Data (C-LL), and Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine (T-CS), China Medical University Hospital, Taichung, Taiwan; and School of Medicine (C-CW, T-CS, A-CC) and Department of Public Health (C-LL, T-CL), China Medical University, Taichung, Taiwan.
    Elevation of Th2 cytokine-driven inflammatory mediators has been reported in acute stage of Henoch-Schönlein purpura (HSP). However, the temporal interaction between Th2-mediated allergic diseases and HSP with renal involvement remains unknown. Herein, we conducted a population-based cohort analysis to investigate the risk of HSP and renal involvement in children with atopic dermatitis (AD) as 1 of the first steps in the atopic march. Read More

    Screening of celiac disease in children with Henoch-Schoenlein purpura.
    Rheumatol Int 2016 May 20;36(5):713-7. Epub 2016 Jan 20.
    Division of Nephrology, Department of Pediatrics, Dokuz Eylül University Medical Faculty, 35340, Balcova, Izmir, Turkey.
    Prevalence of celiac disease (CD) is 2.42 % in healthy Turkish children. The frequency of IgA-associated disorders is increased in CD. Read More

    A higher frequency of CD4(+)CXCR5(+) T follicular helper cells in patients with newly diagnosed Henoch-Schönlein purpura nephritis.
    Int Immunopharmacol 2016 Mar 14;32:8-15. Epub 2016 Jan 14.
    Genetic Diagnosis Center, The First Hospital of Jilin University, Changchun 130021, China; Key Laboratory of Zoonoses Research, Ministry of Education, The First Hospital of Jilin University, Changchun 130021, China; Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou 225009, China. Electronic address:
    T follicular helper (TFH) cells play an important role in the humoral immune responses. The aim of this study was to examine the frequency of different subsets of CD4(+)CXCR5(+) TFH cells and B cells in patients with new-onset Henoch-Schönlein purpura nephritis (HSPN). The numbers of different subsets of CD4(+)CXCR5(+) TFH cells, B cells and the constituents of serum cytokines were detected in a total of 25 patients with newly diagnosed HSPN before and after treatment, and in 14 healthy controls (HC). Read More

    Local leukocyte proliferation as a target for cyclophosphamide in the treatment of Henoch-Schönlein purpura nephritis grade VI.
    Nephrology (Carlton) 2016 Jan;21(1):68-71
    Department of Pediatrics, Niigata University Medical and Dental Hospital, Niigata, Japan.
    Henoch-Schönlein purpura nephritis (HSPN) is one of the most common types of chronic glomerulonephritis in children; however, there have been few reports on the pathogenesis and management of grade VI HSPN. We present the case of a 6-year-old boy with grade VI HSPN accompanied by severe nephrotic syndrome and hypocomplementaemia. Immunohistological studies revealed profound glomerular accumulation of CD45- and CD68-positive inflammatory cells. Read More

    Association between allergic diseases and risks of HSP and HSP nephritis: a population-based study.
    Pediatr Res 2016 Apr 21;79(4):559-64. Epub 2015 Dec 21.
    Department of Pediatric Medicine, Children's Hospital of China Medical University Hospital, Taichung, Taiwan.
    Background: Some allergic inflammation-associated mediators have been reported in acute stage of Henoch-Schönlein purpura (HSP). However, the association of children with allergic diseases and their subsequent risks of HSP and HSP nephritis remain unknown.

    Methods: In this study, we included 2,240 children with HSP diagnosed between 2000 and 2008 as well as 8,960 non-HSP controls matched for age, sex, and level of urbanization. Read More

    Bullous Henoch-Schönlein purpura in children.
    Cutis 2015 Oct;96(4):248-52
    Department of Pediatrics, West Virginia University School of Medicine, Morgantown, USA.
    Henoch-Schönlein purpura (HSP) is a systemic vasculitis that is common in the pediatric population and often presents with the classical triad of palpable purpura, arthralgia, and abdominal pain. We describe a case of HSP in a 14-year-old adolescent girl who presented with atypical features of painful hemorrhagic bullae. The patient was treated with high-dose steroids, dapsone, and supportive therapy with remarkable improvement. Read More

    Evolution of IgA nephropathy into anaphylactoid purpura in six cases--further evidence that IgA nephropathy and Henoch-Schonlein purpura nephritis share common pathogenesis.
    Pediatr Nephrol 2016 May 17;31(5):779-85. Epub 2015 Dec 17.
    Division of Nephrology and Rheumatology, National Center for Child Health and Development, 2-10-1, Okura, Setagaya-ku, Tokyo, 157-8535, Japan.
    Background: As the morphological and immunohistochemical manifestations of immunoglobulin A (IgA) nephropathy and Henoch-Schonlein purpura nephritis (HSPN) are very similar, they are considered to share a common pathogenesis. Although HSPN usually develops after the appearance of anaphylactoid purpura, we have encountered patients whose renal symptoms preceded purpura.

    Methods: We reviewed the clinical courses of patients who were first diagnosed with IgA nephropathy, but developed purpura later, at the National Center for Child Health and Development in Tokyo, Japan. Read More

    Henoch Schonlein purpura associated with bee sting: case report.
    Medwave 2015 Oct 30;15(9):e6297. Epub 2015 Oct 30.
    Departamento de Fisiología, Facultad de Medicina, Universidad Nacional de Trujillo, Trujillo, Perú
    Henoch Schonlein purpura (HSP) is a common childhood vasculitis, characterized by a non-thrombocytopenic palpable purpura and systemic features. It can be triggered by conditions like infections and insect bites. We present the case of a six-year-old girl with palpable maculopapular lesions on the lower limbs, itching, mild pain, swelling of feet, limitation of limb mobility, and a history of bee sting. Read More

    Anaphylactoid Purpura Manifested after Acute Gastroenteritis with Severe Dehydration in an 8-Year-Old Male Child: A Case Report.
    P R Health Sci J 2015 Dec;34(4):225-7
    G.R. Doshi and K.M. Mehta Institute of Kidney diseases and Research Centre (IKDRC) and Dr. H.L. Trivedi Institute of Transplantation Sciences (ITS), Civil Hospital Campus, Gujarat, India.
    Anaphylactoid purpura, also known as Henoch-Schönleinpurpura (HSP), is an IgA-mediated vasculitis that tends to be a benign disease of childhood. Up to 50% of cases are preceded by an upper tract respiratory infection caused by group-A beta-hemolytic streptococcus and present with the common tetrad of abdominal pain, arthritis, purpuric rash, and renal involvement. The majority of patients recover completely. Read More

    [Childhood vasculitis].
    Z Rheumatol 2015 Dec;74(10):863-6, 868-72, 874-7
    Rheumatology, Department of Pediatrics, Alberta Children's Hospital, University of Calgary, 2888 Shaganappi Trail NW, T3B 6A8, Calgary, Alberta, Canada.
    Background: The primary vasculitides are rare conditions in childhood. The most common disease subtypes are Schönlein-Henoch purpura and Kawasaki's syndrome, which frequently have a self-limiting course. In the majority of vasculitides, the etiology remains unknown. Read More

    Pediatric vasculitis.
    Curr Opin Rheumatol 2016 Jan;28(1):29-38
    Department of Pediatric Rheumatology, Cerrahpasa Medical School, Istanbul University, Istanbul, Turkey.
    Purpose Of Review: The aim of this review is to define childhood vasculitis and to highlight new causative factors and treatment modalities under the guidance of recently published studies.

    Recent Findings: Childhood vasculitis is difficult to diagnose because of the wide variation in the symptoms and signs. New nomenclature and classification criteria were proposed for the diagnosis of pediatric vasculitis. Read More

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