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    The relationship between red cell distribution width and the risk of Henoch-Schönlein purpura nephritis.
    Br J Biomed Sci 2017 Oct 9:1-6. Epub 2017 Oct 9.
    a Department of Clinical Laboratory , Guangxi Medical University First Affiliated Hospital , Nanning , China.
    Introduction: Red blood cell distribution width (RDW) is elevated in various inflammatory diseases, but its clinical significance in Henoch-Schönlein purpura nephritis (HSPN) in unknown. The aim of this study was to determine the value of RDW as a risk factor or marker for HSPN in children.

    Methods: This was a case-control study of 105 Henoch-Schönlein purpura (HSP) patients, 120 HSPN patients and 192 healthy controls. Read More

    Cutaneous Manifestations of Small-Vessel Leukocytoclastic Vasculitides in Childhood.
    Clin Rev Allergy Immunol 2017 Dec;53(3):439-451
    Pediatric Department of Southern Switzerland, San Giovanni Hospital, 6500, Bellinzona, Switzerland.
    In childhood, cutaneous small-vessel vasculitides include Henoch-Schönlein syndrome, a systemic vasculitis, and Finkelstein-Seidlmayer syndrome, a skin-limited vasculitis. Both Henoch-Schönlein and Finkelstein-Seidlmayer syndromes are seen more frequently in white or Asian compared with black children and occur especially in winter and spring with a male-to-female ratio of approximately 2:1. In everyday clinical practice, both conditions are diagnosed on clinical grounds without histological confirmation. Read More

    Henoch-Schonlein purpura associated with primary active Epstein-Barr virus infection: a case report.
    Pan Afr Med J 2017 11;27:29. Epub 2017 May 11.
    University of Health Sciences, Umraniye Research and Training Hospital, Department of Pediatrics, Istanbul, Turkey.
    Henoch-Schönlein purpura (HSP) is the most common form of childhood vasculitis. Various viral and bacterial infections, drugs, vaccines, food allergy and even insect bites have been considered as triggering factors in pathogenesis of HSP. Epstein-Barr virus (EBV) infection, which is associated with HSP, have been rarely reported. Read More

    [Association of serum vitamin D level with severity and treatment in children with Henoch-Schönlein purpura].
    Zhongguo Dang Dai Er Ke Za Zhi 2017 Jul;19(7):796-799
    Department of Pediatrics, Guizhou Provincial People's Hospital, Guiyang 550002, China.
    Objective: To investigate the association of serum vitamin D [25-(OH)D3] level with the severity and treatment in children with Henoch-Schönlein purpura (HSP).

    Methods: A total of 50 children with newly-diagnosed HSP between January and December, 2015 were enrolled as HSP group, and 49 healthy children were enrolled as control group. Fasting serum samples were collected, and ELISA was used to measure serum 25-(OH)D3 level. Read More

    Characteristics and Management of IgA Vasculitis (Henoch-Schönlein) in Adults: Data From 260 Patients Included in a French Multicenter Retrospective Survey.
    Arthritis Rheumatol 2017 Sep;69(9):1862-1870
    Department of Nephrology, Hôpital Saint Louis, AP-HP, Université Paris Descartes, Paris, France.
    Objective: Data on adult IgA vasculitis (Henoch-Schönlein) (IgAV) are scarce. This survey was designed to better define the clinical spectrum of IgAV and efficacy of treatments in a French patient population.

    Methods: Data on clinical characteristics, histologic features, and treatment response from 260 patients with IgAV included in a French multicenter retrospective survey were analyzed. Read More

    Association between red blood cell distribution width and Henoch-Schonlein purpura nephritis.
    Medicine (Baltimore) 2017 Jun;96(23):e7091
    aDepartment of Clinical Laboratory bDepartment of Nephrology, Children's Hospital of Zhejiang University School of Medicine, Hangzhou, People's Republic of China.
    To investigate whether red blood cell distribution width (RDW) is a marker of the risk of Henoch-Schonlein purpura (HSP) nephritis (HSPN), a total of 669 HSP patients and 168 healthy controls were included in this retrospective study. Two hundred fifty-six (38.3%) of the patients had kidney involvement. Read More

    [Cutaneous leukocytoclastic vasculitis: about 85 cases].
    Pan Afr Med J 2017 14;26:138. Epub 2017 Mar 14.
    Université du Centre, Tunisie.
    Clinical manifestation, etiology and outcome of leukocytoclastic vasculitis are little studied. The aim of our study was to examine epidemiological, clinical etiological, and evolutionary characteristics of this entity. We conducted a cross-sectional data collection from medical records of 85 patients with leukocytoclastic vasculitis in the Department of Dermatology at the Farhat Hached University Hospital, Sousse between January 2000 and December 2013. Read More

    Incidence of IgA vasculitis in children estimated by four-source capture-recapture analysis: a population-based study.
    Rheumatology (Oxford) 2017 Aug;56(8):1358-1366
    ECSTRA, Université Paris 7-Diderot.
    Objectives: The aim was to describe the epidemiological characteristics of childhood IgA vasculitis (IgAV) defined by the EULAR/PRINTO/Paediatric Rheumatology European Society criteria in a population-based sample from France and ascertain its incidence over 3 years by a four-source capture-recapture analysis.

    Methods: Cases were prospectively collected in Val de Marne county, a suburb of Paris, with 263 874 residents <15 years old. Children with incident IgAV living in this area from 2012 to 2014 were identified by four sources of case notification (emergency departments, paediatrics departments, private-practice paediatricians and general practitioners). Read More

    Association of Endothelial Nitric Oxide Synthase Gene Polymorphism with Susceptibility and Nephritis Development of Henoch-Schönlein Purpura in Chinese Han Children.
    Genet Test Mol Biomarkers 2017 Jun 14;21(6):373-381. Epub 2017 Apr 14.
    3 Department of Pediatrics, The Second Affiliated Hospital of Xi'an Jiaotong University , Xi'an, P.R. China .
    Objective: Henoch-Schönlein purpura (HSP) is the most common form of systemic small-vessel vasculitis in children. Previous studies suggested endothelial nitric oxide synthase (eNOS) plays an important role in the pathogenesis and clinical manifestations of HSP. This study aimed to investigate the potential association between 10 single-nucleotide polymorphisms (SNPs) within the eNOS gene and HSP risk and nephritis development in a Chinese Han population. Read More

    [Association between platelet-activating factor acetylhydrolase gene polymorphisms and gastrointestinal bleeding in children with Henoch-Schönlein purpura].
    Zhongguo Dang Dai Er Ke Za Zhi 2017 Apr;19(4):385-388
    Department of Gastroenterology, Wuhan Children's Hospital, Wuhan 430016, China
    Objective: To study the association between the single nucleotide polymorphisms (SNPs) of the ninth exon Val279Phe of platelet-activating factor acetylhydrolase (PAF-AH) gene and gastrointestinal bleeding in children with Henoch-Schönlein purpura (HSP).

    Methods: A total 516 children with HSP were enrolled, among whom 182 had gastrointestinal bleeding and 334 had no gastrointestinal bleeding. PCR was used to investigate the distribution of genotypes and alleles in the SNPs of Val97Phe. Read More

    Ambulatory arterial stiffness index, blood pressure variability, and nocturnal blood pressure dip in children with IgA and Henoch-Schönlein nephropathy
    Clin Nephrol 2017 Jun;87(6):301-309
    Aim: Evaluation of mean blood pressure values, ambulatory arterial stiffness index (AASI), pulse pressure (PP), blood pressure variability (BPV), and circadian blood pressure rhythm using ambulatory blood pressure monitoring (ABPM) in children with IgA nephropathy and Henoch-Schönlein nephropathy (IgAN/HSN).

    Material And Methods: In 48 children (29 with IgAN, 19 with HSN) aged 14.04 ± 3. Read More

    [Association between CTLA-4 gene polymorphism and Henoch-Schönlein purpura in children].
    Zhongguo Dang Dai Er Ke Za Zhi 2017 Mar;19(3):296-302
    Department of Pediatrics, Xi'an Central Hospital, Xi'an 710003, China.
    Objective: To investigate the association between CTLA-4 gene polymorphism and Henoch-Schönlein purpura (HSP) in children.

    Methods: Sixty children who were diagnosed with HSP were enrolled as the case group, consisting of 33 males and 27 females. Thirty healthy children were enrolled as the control group. Read More

    [Changes in 25-hydroxyvitamin D3 level in children with Henoch-Schönlein purpura].
    Zhongguo Dang Dai Er Ke Za Zhi 2017 Mar;19(3):292-295
    Department of Pediatrics, Baoding Children's Hospital, Baoding, Hebei 071000, China.
    Objective: To examine the changes in 25-hydroxyvitamin D3 [25-(OH)D3] level in children with Henoch-Schönlein purpura (HSP) and its clinical significance.

    Methods: A total of 92 HSP children were included in this study, and were divided into HSP nephritis (HSPN) group (31 cases) and HSP group (61 cases) based on the presence or absence of HSPN. Alternatively, the patients were divided into purpura alone group (22 cases), purpura with joint symptoms group (joint symptom group, 24 cases), purpura with gastrointestinal symptoms group (gastrointestinal symptom group, 20 cases), and purpura with joint and gastrointestinal symptoms (mixed group, 26 cases) based on their clinical symptoms. Read More

    Evaluation of TGF-β1 and MCP-1 expression and tubulointerstitial fibrosis in children with Henoch-Schönlein purpura nephritis and IgA nephropathy: A clinical correlation.
    Clinics (Sao Paulo) 2017 Feb 1;72(2):95-102. Epub 2017 Feb 1.
    The Children's Hospital of Zhejiang University School of Medicine, Department of Nephrology, Hangzhou 310003, Zhejiang Province, China.
    Objectives:: Henoch-Schönlein purpura nephritis and immunoglobulin A nephropathy are two diseases with similar clinical presentations but very different prognoses. Transforming growth factor β1 and monocyte chemoattractant protein-1 have been associated with the development of tissue fibrosis. We examined the development of tubulointerstitial fibrosis and its relationship with Transforming growth factor β1 and monocyte chemoattractant protein-1 expression in these patients. Read More

    A single-center analysis of Henoch-Schonlein purpura nephritis with nephrotic proteinuria in children.
    Pediatr Rheumatol Online J 2017 Mar 4;15(1):15. Epub 2017 Mar 4.
    Department of Nephrology and Rheumatology, Shanghai Children's Hospital, Shanghai Jiao Tong University, 355 Luding Road, Shanghai, 200062, People's Republic of China.
    Background: In children with Henoch-Schonlein purpura nephritis (HSPN), the degree of proteinuria has been proven to be not only a sign of kidney damage, but also an accelerator of kidney disease progression. Nephrotic proteinuria at disease onset has been proposed as a predictor of a poor renal outcome. This study aims to assess the clinical and pathological features of HSPN with nephrotic proteinuria in a single center. Read More

    Henoch Schönlein Purpura Nephritis Associated with Intravesical Bacillus Calmette-Guerin (BCG) Therapy.
    Intern Med 2017 1;56(5):541-544. Epub 2017 Mar 1.
    Department of Nephrology, Showa General Hospital, Japan.
    Henoch Schönlein purpura (HSP), also known as IgA vasculitis (IgAV), is a systemic small-vessel vasculitis that predominantly affects adolescents and is rare in adults. In many cases, the onset of HSP has been causally linked to an infectious disease. We encountered a case of HSP with severe renal involvement diagnosed by renal biopsy following bacillus Calmette-Guerin (BCG) therapy for bladder cancer. Read More

    [Comparison of age-based clinical and abnormal immune parameters in patients with Henoch-Schönlein purpura].
    Zhonghua Xue Ye Xue Za Zhi 2017 Jan;38(1):60-64
    Institute of Hematology & Blood Diseases Hospital, CAMS & PUMC, Tianjin 300020, China.
    Objective: To explore age-based clinical and immune parameters in Henoch-Schönlein purpura (HSP) to determine clinically useful markers reflecting disease characteristic. Methods: A cohort of 502 patients with HSP were enrolled into this retrospective study to evaluate their clinical and immune data. Results: Majority HSP cases occurred at age ≤14 years and showed significant immune imbalances of ESR, CD3(+) cells, CD4(+) cells, CD3(-)CD16(+)CD56(+) cells, CD4(+)/CD8(+) cells, IgG, IgA, IgM, IgE, complements C3/C4 and ASO in the acute phase. Read More

    A Case of Henoch-Schonlein Purpura Associated with Rotavirus Infection in an Elderly Asian Male and Review of the Literature.
    Am J Case Rep 2017 Feb 8;18:136-142. Epub 2017 Feb 8.
    Department of Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
    BACKGROUND Henoch-Schönlein purpura (HSP), a small vessel vasculitis mediated by deposition of immune-complexes containing IgA in the skin, gut, and glomeruli, often presents with abdominal pain, purpuric rash in the lower extremities and buttocks, joint pain, and hematuria. The disease most commonly targets children but can affect adults who tend to have a worse prognosis. CASE REPORT We discuss a case of HSP in an elderly Chinese male who presented with severe proximal bowel inflammation, vasculitic rash, and proteinuria; he was found to have positive stool rotavirus and giardia. Read More

    Correlation Between Clinicaland Pathological Characteristics of Henoch-Schönlein Purpura Nephritis in Adults.
    Iran J Kidney Dis 2016 Jan;11(1):12-17
    Department of Nephrology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province, China.
    Introduction: Henoch-Schönlein purpura nephritis (HSPN) mainly affects children and is less common in adults, but its associated pathological changes are severe in adults, in whom it results in a poor prognosis. This study aimed to analyze the clinical and pathological characteristics of HSPN in adults and to identify the correlations among them.

    Materials And Methods: Clinical and pathological data from139 patients older than 18 years of age who had been diagnosed with HSPN and had received renal biopsy at our center from January 2012 to November 2014 were collected and were grouped according to the different conditions and analyzed retrospectively. Read More

    Multicentric Castleman's disease associated with IgA vasculitis (Henoch-Schönlein purpura) responding well to tocilizumab: a case report.
    Clin Rheumatol 2017 Mar 6;36(3):729-733. Epub 2017 Feb 6.
    Nephrology Center, Toranomon Hospital, 2-2-2, Toranomon, Minato, Tokyo, 105-8470, Japan.
    A 41-year-old man was referred to our hospital for the evaluation of hypergammaglobulinemia (IgG 2898 mg/dL and IgA 587 mg/dL), inflammation (CRP 6.7 mg/dL and serum interleukin-6 (IL-6) 15.1 ng/L), and anemia (Hb 10. Read More

    Blistering eruptions in childhood Henoch-Schönlein syndrome: systematic review of the literature.
    Eur J Pediatr 2017 Apr 4;176(4):487-492. Epub 2017 Feb 4.
    Pediatric unit, Università degli Studi di Milano, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
    The occurrence of blistering eruptions in childhood Henoch-Schönlein syndrome has been so far addressed exclusively in individual case reports. To describe epidemiology, clinical presentation, and therapeutic options in Henoch-Schönlein patients ≤18 years of age with blistering eruptions, we completed a systematic literature search. For the final analysis, we retained 39 reports. Read More

    Posterior reversible encephalopathy syndrome as a complication of Henoch-Schönlein purpura in a seven-year-old girl.
    Scott Med J 2017 Feb 2;62(1):34-37. Epub 2017 Feb 2.
    3 Community Regional College of Chapecó, Brazil.
    Introduction Henoch-Schönlein purpura is a multisystem small vessel vasculitis. Neurologic manifestations are uncommon. Posterior reversible encephalopathy syndrome is a rare complication of Henoch-Schönlein purpura with typical clinical and neuroimaging findings that occurs most commonly in the setting of severe hypertension and renal injury. Read More

    Endothelial function in children with a history of henoch schonlein purpura.
    Pediatr Rheumatol Online J 2017 Jan 14;15(1). Epub 2017 Jan 14.
    Department of Pediatrics B, Meyer Children's Hospital, Rambam Medical Center, Haifa, Israel.
    Background: Although Henoch-Schonlein purpura (HSP) is the most common form of systemic vasculitis in children, the long term effect of HSP on endothelial function is still not clear. The aim of our study was to evaluate the long term effect of HSP on endothelial function in children and adolescents.

    Methods: This research was an observational prospective study. Read More

    Ibuprofen-induced Henoch-Schönlein purpura nephritis: First reported case.
    Indian J Pharmacol 2016 Nov-Dec;48(6):739-740
    Department of Nephrology, Serdang Hospital, Kajang, Selangor, Malaysia.
    Ibuprofen is a nonsteroidal anti-inflammatory drug that is used widely in treating pain, fever, and inflammation. Its side effects are mainly due to acute renal impairment and gastric discomfort. We hereby report a rare case of Henoch-Schönlein purpura nephritis secondary to ibuprofen consumption which has not been reported in literature before. Read More

    Henoch-Schönlein purpura as a rare cause of an acute abdomen.
    Ann R Coll Surg Engl 2017 Feb 4;99(2):e88-e90. Epub 2017 Jan 4.
    Lancashire Teaching Hospitals NHS Foundation Trust , UK.
    A 52-year-old man presented with a purpuric rash affecting his legs and hypertension. He was diagnosed with Henoch-Schönlein purpura and discharged with non-steroidal anti-inflammatory drugs. Three weeks later, he presented again with loss of appetite and vomiting before developing abdominal pain with pyrexia of 38. Read More

    [IgA vasculitis (Henoch-Schönlein purpura)].
    Wiad Lek 2016;69(5):711-713
    Katedra i Klinika Nefrologii, Dializoterapii i Chorób Wewnętrznych WUM, Warszawa, Polska.
    IgA vasculitis (Schönlein-Henoch purpura) is a systemic inflammation of the small vessels associated with the deposition of IgA antibodies in the vascular wall. Typical clinical symptoms are: skin lesions (purpura), joint pain, abdominal discomfort and renal disorder (most common haematuria/proteinuria). The disease affects usually the pediatric population; in those patients its course is benign and usually not associated with permanent complications. Read More

    Henoch-Schönlein Purpura With Muscle Involvement, Presenting as Myositis.
    J Clin Rheumatol 2017 Jan;23(1):60-62
    Department of Internal Medicine, Graduate School, Kyung Hee University, College of Medicine, Kyung Hee University Hospital at Gangdong, Seoul, South Korea Division of Rheumatology, Department of Internal Medicine, Kyung Hee University, College of Medicine, Kyung Hee University Medical Center, Seoul, South Korea Division of Rheumatology, Department of Internal Medicine, Kyung Hee University, College of Medicine, Kyung Hee University Hospital at Gangdong, Seoul, South Korea Division of Rheumatology, Department of Internal Medicine, Kyung Hee University, College of Medicine, Kyung Hee University Medical Center, Seoul, South Korea Division of Rheumatology, Department of Internal Medicine, Kyung Hee University, Kyung Hee University Hospital at Gangdong, Seoul, South Korea Division of Rheumatology, Department of Internal Medicine, Kyung Hee University, College of Medicine, Kyung Hee University Medical Center, Seoul, South Korea Division of Rheumatology, Department of Internal Medicine, Kyung Hee University, College of Medicine, Kyung Hee University Hospital at Gangdong, Seoul, South Korea

    Paediatric rheumatology clinic population in Southeast Asia: are we different?
    Rheumatology (Oxford) 2017 Mar;56(3):390-398
    Pediatric Rheumatology Section, Department of Pediatrics, University of Santo Tomas Hospital, Manila, Philippines.
    Objectives.: To examine the descriptive epidemiology of the patient population referred to paediatric rheumatology centres (PRCs) in Southeast Asia (SEA) and to compare the frequency of conditions encountered with other PRC populations.

    Methods. Read More

    Acrally distributed dermatoses: Vascular dermatoses (purpura and vasculitis).
    Clin Dermatol 2017 Jan - Feb;35(1):68-80. Epub 2016 Sep 10.
    Department of Dermatology and Venereology, Tokuda Hospital Sofia, Sofia, Bulgaria.
    Purpuric lesions appear in acral distribution in a variety of conditions and often provide clues to the clinical diagnosis. Purpuric means "hemorrhagic"-that is, the lesions do not blanch from pressure. This review focuses on dermatoses that produce hemorrhagic lesions in acral distribution from the large groups of the vasculitic diseases and their mimics. Read More

    Risk Factors Associated with Renal Involvement in Childhood Henoch-Schönlein Purpura: A Meta-Analysis.
    PLoS One 2016 30;11(11):e0167346. Epub 2016 Nov 30.
    Department of Nephrology, Key Laboratory of the Ministry of Education, Children's Hospital of Chongqing Medical University, Chongqing, People's Republic of China.
    Background And Objective: Henoch-Schönlein purpura (HSP) is an important cause of chronic kidney disease in children. This meta-analysis identified risk factors associated with renal involvement in childhood HSP.

    Methods: PubMed, Embase, and Web of Science were searched. Read More

    Rare urological manifestation of Henoch-Schönlein purpura: testicular torsion.
    BMJ Case Rep 2016 Nov 11;2016. Epub 2016 Nov 11.
    Department of Urology, Maxima Medisch Centrum, Eindhoven, The Netherlands.
    The Henoch-Schönlein purpura (HSP) is a systemic vasculitis that mostly occurs in children. Besides the most common clinical manifestations such as palpable purpura, arthralgia, abdominal pain and renal disease, it can have urological manifestations. We report a rare case of a 2-year-old boy with the HSP who developed a testicular torsion under corticosteroid treatment. Read More

    Mechanism of feedback regulation of neutrophil inflammation in Henoch-Schönlein purpura.
    Eur Rev Med Pharmacol Sci 2016 Oct;20(20):4277-4285
    Clinical Laboratory, Cangzhou Central Hospital, Hebei, China.
    Objective: The aim of this study is to investigate the role of complement-neutrophil feedback regulation of inflammatory response in Henoch-Schönlein purpura (HSP) through constructing an animal model of HSP.

    Materials And Methods: Twenty-four SPF grade Japanese large-eared white rabbits were randomly divided into normal group and model group, 12 for each group. HSP model was constructed by challenging rabbits with gastric gavage of a decoction solution containing ginger, Piper longum L. Read More

    Henoch-Schönlein purpura with c-ANCA antibody in an adult.
    An Bras Dermatol 2016 Sep-Oct;91(5):667-669
    Universidade Federal de Mato Grosso do Sul (UFMS) - Campo Grande (MS), Brazil.
    The Henoch-Schönlein purpura is the vasculitis associated with deposits of immunoglobulin A in small vessels. Its association with cytoplasmic antineutrophil cytoplasmic antibodies is possible, but rare. This vasculitis is uncommon in adults and the main clinic manifestations are purpuric lesions in lower limbs with gastrointestinal symptoms and renal involvement. Read More

    Staphylococcus Infection-Associated GN - Spectrum of IgA Staining and Prevalence of ANCA in a Single-Center Cohort.
    Clin J Am Soc Nephrol 2017 Jan 7;12(1):39-49. Epub 2016 Nov 7.
    Department of Pathology, and.
    Background And Objectives: Staphylococcus infection-associated GN (SAGN) is a well recognized disease entity, particularly because of the frequent IgA-dominant glomerular immunoglobulin staining on kidney biopsy. Biopsy features can resemble two other disease entities - primary IgA nephropathy and Henoch-Schönlein purpura nephritis - posing a diagnostic pitfall. This is clinically relevant because of the crucial difference in the therapeutic approach. Read More

    The association between MEFV gene polymorphisms and Henoch-Schönlein purpura, and additional SNP-SNP interactions in Chinese Han children.
    Rheumatol Int 2017 Mar 31;37(3):455-460. Epub 2016 Oct 31.
    Department of Pediatrics, Zhongnan Hospital of Wuhan University, No. 169 East Lake Road, Wuchang District, Wuhan City, 430071, Hubei Province, China.
    The aim of this study was to investigate the association between single-nucleotide polymorphisms (SNP) within MEFV gene and Henoch-Schönlein purpura (HSP) risk, and the impact of SNP-SNP interaction on HSP risk in Chinese children. A total of 662 subjects with a mean age of 7.9 ± 2. Read More

    Approach to cutaneous vasculitides with special emphasis on small vessel vasculitis: histopathology and direct immunofluorescence.
    Curr Opin Rheumatol 2017 Jan;29(1):39-44
    Department of Pathology, Acıbadem University, Istanbul, Turkey.
    Purpose Of Review: The present review will focus on recent publications in cutaneous vasculitides.

    Recent Findings: Some histopathological and clinical features, such as papillary dermal edema, perivascular C3 deposition, clinically evident edema, and lesions above the waist, may point out renal or gastrointestinal involvement in Henoch-Schönlein purpura (HSP). HSP associated with familial Mediterranean fever differs from typical isolated HSP by showing no deposits of IgA, much younger age, and location of the lesions on the face or the trunk. Read More

    Disseminated penicilliosis due to Penicillium chrysogenum in a pediatric patient with Henoch-Schönlein syndrome.
    Int J Infect Dis 2016 Oct 3;51:78-80. Epub 2016 Sep 3.
    Department of Microbiology, ENCB, Instituto Politécnico Nacional, Mexico City, Mexico.
    A case of disseminated infection caused by Penicillium chrysogenum in a 10-year-old boy with a history of Henoch-Schönlein purpura and proliferative glomerulonephritis, treated with immunosuppressors, is reported herein. The patient had a clinical picture of 2 weeks of fever that did not respond to treatment with broad-spectrum antibiotics and amphotericin B. Computed tomography imaging showed diffuse cotton-like infiltrates in the lungs, hepatomegaly, mesenteric lymphadenopathy, and multiple well-defined round hypodense lesions in the spleen. Read More

    Histopathological and immunological changes during the acute and recovery phase in Henoch-Schönlein purpura rabbit model.
    Arch Dermatol Res 2017 Jan 21;309(1):21-30. Epub 2016 Oct 21.
    Key Laboratory of Human Diseases Comparative Medicine, Ministry of Health, Beijing, People's Republic of China.
    Henoch-Schönlein purpura (HSP) is a systemic vasculitis mediated by autologous immune complex. Animal models of HSP are scarce. Here, we describe the characteristics of HSP rabbit model in the acute and recovery phase. Read More

    Vasculitis in the autoinflammatory diseases.
    Curr Opin Rheumatol 2017 Jan;29(1):4-11
    Rheumatology Unit, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.
    Purpose Of Review: This article addresses the prevalence and relationship between autoinflammatory diseases and vasculitis.

    Recent Findings: Autoimmune diseases (AIDs) are a group of syndromes characterized by episodes of unprovoked inflammation due to dysregulation of the innate immune system. Despite the common occurrence of rashes and other skin lesions in these diseases, vasculitis is reported in only a few. Read More

    Differences in pathological characteristics and laboratory indicators in adult and pediatric patients with Henoch-Schönlein purpura nephritis.
    J Huazhong Univ Sci Technolog Med Sci 2016 Oct 18;36(5):659-666. Epub 2016 Oct 18.
    Department of Nephrology, the First Hospital of Jilin University, Changchun, 130021, China.
    We aimed to investigate the differences in renal histopathological changes and laboratory parameters between adult and pediatric patients with Henoch-Schönlein purpura nephritis (HSPN), and to analyze the correlation between laboratory parameters and renal histopathological grading. A total of 139 patients diagnosed with HSPN between September 2010 and December 2014 at the First Hospital of Jilin University, China, were retrospectively reviewed. The clinical and pathological characteristics were examined and compared between the adult and the pediatric patients. Read More

    [Clinical effect of gamma globulin pulse therapy for abdominal Henoch-Schönlein purpura in children].
    Zhongguo Dang Dai Er Ke Za Zhi 2016 Oct;18(10):988-990
    Department of Pediatrics, Renmin Hospital of Wuhan University, Wuhan 430060, China.
    Objective: To study the clinical effect of high-dose gamma globulin pulse therapy for abdominal Henoch-Schönlein purpura (HSP).

    Methods: Thirty-three children with abdominal HSP were randomly assigned to dexamethasone group (15 children) and gamma globulin group (18 children). The children in the dexamethasone group were treated with dexamethasone and conventional treatment, and those in the gamma globulin group were treated with high-dose gamma globulin pulse therapy in addition to the conventional treatment. Read More

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