4,425 results match your criteria Henoch-Schonlein Purpura Anaphylactoid Purpura


[Renal prognosis of IgA vasculitis nephritis in adult patients: a monocentric study of 25 cases].

Pan Afr Med J 2018 4;31. Epub 2018 Sep 4.

Service de Médecine Interne A, Hopital Charles Nicolle, Tunis, Tunisie.

IgA vasculitis nephritis affects the prognosis of this disease in adult patients. This study aimed to examine the clinical characteristics of this renal involvement in adults and to identify factors influencing renal prognosis. We conducted a retrospective monocentric study of patients with histologically confirmed IgA vasculitis nephritis (rheumatoid purpura) (EULAR classification criteria) with renal involvement classified according to Pillebout classification. Read More

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http://dx.doi.org/10.11604/pamj.2018.31.9.10594DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431421PMC
April 2019
1 Read

[Rapid progressive glomerulonephritis].

Authors:
Marion Haubitz

Internist (Berl) 2019 Mar 13. Epub 2019 Mar 13.

Medizinische Klinik III - Nieren- und Hochdruckerkrankungen, Klinikum Fulda gAG, Universitätsmedizin Marburg - Campus Fulda, Pacelliallee 4, 36043, Fulda, Deutschland.

The rapid progressive glomerulonephritis is an emergency case. Renal function is rapidly lost within weeks or a few months (rarely within days) due to necrotizing extracapillary proliferative crescentic glomerulonephritis. Early diagnosis and treatment improve prognosis, as the best prognostic marker is creatinine when treatment is initiated. Read More

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http://link.springer.com/10.1007/s00108-019-0575-x
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http://dx.doi.org/10.1007/s00108-019-0575-xDOI Listing
March 2019
5 Reads

Different histological classifications for Henoch-Schönlein purpura nephritis: which one should be used?

Pediatr Rheumatol Online J 2019 Feb 28;17(1):10. Epub 2019 Feb 28.

Department of Pediatrics, Hacettepe University, Ankara, Turkey.

Background: Nephritis is the most important chronic complication of IgA Vasculitis (IgAV)/Henoch-Schönlein purpura (IGAV/HSP) and thus the main prognostic factor of this most common childhood vasculitis. Since the prognosis and treatment selection depends on the mode of interpretation of biopsy material, in this manuscript we have presented several issues related to the uneven application of different histological classifications in IgAV/Henoch-Schönlein purpura nephritis (HSPN). The nephritis of IgAV/IGAV/HSP will be abbreviated as HSPN for this paper. Read More

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http://dx.doi.org/10.1186/s12969-019-0311-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393980PMC
February 2019
1 Read

[Value of galactose-deficient IgA1 in the early diagnosis of Henoch-Schönlein purpura nephritis in children].

Zhongguo Dang Dai Er Ke Za Zhi 2019 Feb;21(2):172-175

Department of Nephrology and Rheumatology, Hunan Children's Hospital/Academy of Pediatrics of University of South China, Changsha 410007, China.

Objective: To explore the value of galactose-deficient IgA1 (Gd-IgA1) in the early diagnosis of Henoch-Schönlein purpura nephritis (HSPN) in children.

Methods: A total of 67 hospitalized children who were definitely diagnosed with HSPN between January and April 2018 and 58 hospitalized children with Henoch-Schönlein purpura (HSP) were enrolled in the study. Twenty children undergoing routine physical examinations served as controls. Read More

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February 2019
1 Read

[Clinical effect of alanyl-glutamine-enriched nutritional support in the treatment of children with abdominal Henoch-Schönlein purpura].

Zhongguo Dang Dai Er Ke Za Zhi 2019 Feb;21(2):168-171

Department of Pediatric Gastroenterology, Chengdu Women and Children's Central Hospital, Chengdu 610091, China.

Objective: To study the clinical effect of alanyl-glutamine-enriched nutritional support in the treatment of children with abdominal Henoch-Schönlein purpura.

Methods: Children with abdominal Henoch-Schönlein purpura who needed nutritional support were enrolled and stratified according to age, sex and the severity of disease, and were randomly divided into a control group (n=118) and an enriched nutritional support group (n=107). The control group was given nutritional support without using alanyl-glutamine, while the enriched nutritional support group was given alanyl-glutamine-enriched nutritional support. Read More

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February 2019

Anaphylactoid Syndrome of Pregnancy.

Nurs Womens Health 2019 Feb;23(1):38-48

Anaphylactoid syndrome of pregnancy (ASP) is a widespread, proinflammatory, anaphylactic-like reaction that can occur when amniotic fluid enters the maternal blood circulation. ASP is characterized by four cardinal findings: respiratory distress, altered mental status, hypotension, and disseminated intravascular coagulation. ASP is commonly associated with maternal and neonatal mortality. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S17514851183023
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http://dx.doi.org/10.1016/j.nwh.2018.11.006DOI Listing
February 2019
17 Reads

[Role of hypomethylation of suppressor of cytokine signaling in T helper 17 cell/regulatory T cell imbalance in children with Henoch-Schönlein purpura].

Zhongguo Dang Dai Er Ke Za Zhi 2019 Jan;21(1):38-44

Department of Pediatric Cardiology, Nephrology and Rheumatism, Affliated Hospital of Qingdao University, Qingdao, Shandong 266003, China.

Objective: To investigate the association between suppressor of cytokine signaling (SOCS) hypomethylation and T helper 17 (Th17) cell/regulatory T (Treg) cell imbalance in children with Henoch-Schönlein purpura (HSP) and the immune pathogenesis of HSP.

Methods: A total of 32 children in the acute stage of HSP who were hospitalized from May 2014 to January 2015 were enrolled as subjects, and 28 children who underwent physical examination were enrolled as normal control group. ELISA was used to measure the plasma level of interleukin-6 (IL-6). Read More

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January 2019
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The change of Th17/Treg cells and IL-10/IL-17 in Chinese children with Henoch-Schonlein purpura: A PRISMA-compliant meta-analysis.

Medicine (Baltimore) 2019 Jan;98(3):e13991

Department of Pediatrics.

Background: To date, the relationship of Th17 and Treg cells to Henoch-Schonlein purpura (HSP) in children remains controversial. Therefore, a systematic review and meta-analysis was conducted to reveal the potential role of the Th17 and Treg cells in children in acute stage of HSP.

Methods: PubMed, Embase, Web of Science and China National Knowledge Internet (CNKI) were systematically searched for eligible studies up to November 03, 2017. Read More

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http://dx.doi.org/10.1097/MD.0000000000013991DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370168PMC
January 2019
2 Reads
5.723 Impact Factor

Acute hemorrhagic edema of infancy: guide to prevent misdiagnosis.

Cutis 2018 Nov;102(5):359-362

Department of Dermatology, Geisinger Health System, Danville, Pennsylvania, USA.

We report the case of a 10-month-old previously healthy boy who presented with acute rash, edema, and low-grade fever in the setting of recent diarrhea. We differentiate between acute hemorrhagic edema of infancy (AHEI) and Henoch-Schönlein purpura (HSP). Read More

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November 2018
15 Reads

Successful treatment of hemorrhagic bullous Henoch-Schonlein purpura with intravenous immunoglobulins.

Pediatr Dermatol 2019 Jan 18;36(1):e34-e36. Epub 2018 Dec 18.

Department of Paediatrics, Santobono-Pausilipon Children's Hospital, Naples, Italy.

Henoch-Schonlein purpura (HSP) is the most common systemic vasculitis in childhood. There is no consensus about the management for isolated cutaneous manifestations in HSP. We describe a case of HSP presenting with severe skin lesions that did not respond to standard therapy with corticosteroids. Read More

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http://dx.doi.org/10.1111/pde.13715DOI Listing
January 2019
2 Reads

Henoch-Schönlein Purpura After Living Donor Liver Transplantation: Report of the First Case.

Transplant Proc 2018 Dec 9;50(10):4050-4052. Epub 2018 Mar 9.

Division of Hepato-Biliary-Pancreatic and Transplant Surgery, Department of Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.

Henoch-Schönlein purpura (HSP) is a systemic vasculitis affecting the small vessels that mainly presents in children and young adults. It is characterized by tissue deposition of immunoglobulin A (IgA) immune complexes with the classic manifestations of purpura, arthritis, arthralgia, and gastrointestinal and renal involvements. We report a case of HSP nephritis that occurred 2 years after living-donor liver transplantation (LDLT). Read More

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http://dx.doi.org/10.1016/j.transproceed.2018.02.072DOI Listing
December 2018
3 Reads

[Effect of miR-21 on the expression of interleukin-10 in B cell of patients with Henoch-Schonlein purpura].

Zhonghua Er Ke Za Zhi 2018 Dec;56(12):939-944

Rheumatology & Immunology Department of Shenzhen Children's Hospital, Shenzhen 518038, China.

To investigate the effect of microRNAs (miR)-21 on the expression of interleukin (IL)-10 in B cell of patients with Henoch-Schonlein purpura (HSP). From March 2016 to January 2017, twenty-four children with HSP hospitalized in rheumatology and immunology department of Shenzhen Children's Hospital were enrolled into the study, including 12 males and 12 females. Patients were divided into purpura nephritis group (HSPN, 14 cases) and non-nephritis group (NHSPN, 10 cases). Read More

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http://dx.doi.org/10.3760/cma.j.issn.0578-1310.2018.12.010DOI Listing
December 2018
5 Reads

MEFV gene variants in children with Henoch-Schönlein purpura and association with clinical manifestations: a single-center Mediterranean experience.

Postgrad Med 2019 Jan 12;131(1):68-72. Epub 2018 Dec 12.

a Department of Pediatric Rheumatology , Cukurova University Faculty of Medicine , Adana , Turkey.

Objectives: Henoch-Schönlein purpura (HSP) is characterized by non-thrombocytopenic palpable purpura, abdominal pain, and arthralgia/arthritis. We aimed to describe the clinical presentations of children with HSP in a single center and compare the prevalence of each manifestations between patients with MEFV variants, particularly in exon 10 and those without.

Methods: This cohort retrospectively included 144 HSP (59 females, 85 males) patients without Familial Mediterranean Fever (FMF) symptoms and followed for at least 6 months. Read More

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http://dx.doi.org/10.1080/00325481.2019.1552479DOI Listing
January 2019
10 Reads

Atypical purpura location in a pediatric patient with Henoch-Schönlein purpura: A case report.

Medicine (Baltimore) 2018 Nov;97(48):e13294

Department of Laboratory, Children's Hospital, Zhejiang University School of Medicine, Hangzhou, China.

Rationale: The presence of purpura is a compulsory criteria for the diagnosis of Henoch-Schönlein purpura (HSP). Typical purpura of HSP is distributed symmetrically over the extensor surfaces of the lower limbs, buttocks, and forearms with the occasional involvement of trunk and face in children. It occurs only involving the bottom of the feet has never been reported. Read More

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http://dx.doi.org/10.1097/MD.0000000000013294DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283069PMC
November 2018
10 Reads

Connective Tissue Disease: Current Concepts.

Dermatol Clin 2019 Jan 1;37(1):37-48. Epub 2018 Nov 1.

Departments of Dermatology and Pathology, Cleveland Clinic Lerner College of Medicine, 9500 Euclid Avenue A61, Cleveland, OH 44195, USA. Electronic address:

Connective tissue diseases often prominently affect the skin, requiring dermatologists to play an important role in diagnosis and treatment of these patients. Herein we describe updates on the pathogenesis, clinical features, and treatment of 4 major connective tissue diseases: dermatomyositis, cutaneous lupus erythematosus, limited scleroderma (morphea), and cutaneous vasculitis. Many of these updates promise to improve clinical care of patients who suffer from dermatologic involvement of these diseases and are the result of research performed by dermatologists who have expertise in these conditions. Read More

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http://dx.doi.org/10.1016/j.det.2018.07.006DOI Listing
January 2019
2 Reads

Cord-derived mesenchymal stem cells therapy for liver cirrhosis in children with refractory Henoch-Schonlein purpura: A case report.

Medicine (Baltimore) 2018 Nov;97(47):e13287

Department of Pediatrics, Shandong Provincial Qianfoshan Hospital of Shandong University, Jinan, China.

Rationale: To explore the curative effect of human umbilical cord-derived mesenchymal stem cell (ucMSC) therapy for patients with liver cirrhosis complicated with immune thrombocytopenia and refractory Henoch-Schonlein purpura (HSP).

Patient Concerns: A 12-year-old boy presented to our hospital with an 11-month history of purpura on the skin of both lower limbs accompanied by thrombocytopenia. The patient had a history of repeated swelling and painful dorsum pedis, followed by skin redness. Read More

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http://dx.doi.org/10.1097/MD.0000000000013287DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392614PMC
November 2018
23 Reads

Expression of DENDRIN in several glomerular diseases and correlation to pathological parameters and renal failure - preliminary study.

Diagn Pathol 2018 Nov 20;13(1):90. Epub 2018 Nov 20.

Department of Pathology, Forensic medicine and Cytology, University Hospital Centre Split, Split, Croatia.

Background: In glomerular injury dendrin translocates from the slit diaphragm to the podocyte nucleus, inducing apoptosis. We analyzed dendrin expression in IgA glomerulonephritis and Henoch Schönlein purpura (IgAN/HSP) versus in podocytopathies minimal change disease (MCD) and focal segmental glomerulosclerosis (FSGS), and compared it to pathohistological findings and renal function at the time of biopsy and the last follow-up.

Methods: Twenty males and 13 females with median of age 35 years (min-max: 3-76) who underwent percutaneous renal biopsy and had diagnosis of glomerular disease (GD) were included in this retrospective study. Read More

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http://dx.doi.org/10.1186/s13000-018-0767-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247684PMC
November 2018
52 Reads

Immunoglobulin A Nephropathy and Immunoglobulin A Vasculitis.

Pediatr Clin North Am 2019 02;66(1):101-110

Department of Pediatrics, Medical University of South Carolina, 96 Jonathan Lucas Street, 428 CSB, MSC 608, Charleston, SC 29425, USA. Electronic address:

Henoch-Schönlein purpura nephritis and immunoglobulin A nephropathy are common glomerulopathies in the pediatric population that deserve special attention. In some cases the primary care provider can follow the patient but others need more intensive management. Delaying this treatment can lead to worse morbidity. Read More

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http://dx.doi.org/10.1016/j.pcl.2018.08.008DOI Listing
February 2019
3 Reads

Rituximab treatment for chronic steroid-dependent Henoch-Schonlein purpura: 8 cases and a review of the literature.

Pediatr Rheumatol Online J 2018 Nov 14;16(1):71. Epub 2018 Nov 14.

Department of Pediatrics, Division of Rheumatology, University of Alabama at Birmingham, 1600 7th Ave S, CPPN G10, Birmingham, AL, 35233, USA.

Background: Henoch-Schonlein purpura (HSP) is a small vessel vasculitis that is characterized by non-thrombocytopenic purpura, abdominal pain, arthritis, and glomerulonephritis. Typically, HSP is self-limited requiring only supportive care, but more severe cases may require corticosteroid (CS) treatment. Rarely, a subset of these patients has persistent rash, arthritis, abdominal involvement, or renal disease despite treatment with CS, or has disease recurrence on CS tapering. Read More

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https://ped-rheum.biomedcentral.com/articles/10.1186/s12969-
Publisher Site
http://dx.doi.org/10.1186/s12969-018-0285-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6236882PMC
November 2018
36 Reads

A 19-year old man with IgA vasculitis after vaccination.

Braz J Infect Dis 2018 Sep - Oct;22(5):442-444. Epub 2018 Oct 30.

UTHealth - McGovern Medical School, Division of Infectious Diseases, Department of Internal Medicine, Houston, United States; UTHealth - McGovern Medical School, Center for Antimicrobial Resistance and Microbial Genomics (CARMiG) and Division of Infectious Diseases, Houston, United States; UTHealth - School of Public Health, Center for Infectious Diseases, Houston, United States; Universidad El Bosque, Centro Internacional de Genómica Microbiana, Unidad de Genética Molecular y Resistencia Antimicrobiana, Bogota, Colombia. Electronic address:

A 19-year-old patient who mistakenly received two doses of influenza vaccine 10 days before presentation, was admitted with malaise, weakness, and a purpuric non-blanching rash most prominent on the ankles followed by abdominal pain and hematochezia 72h later. The diagnosis of influenza vaccine-related Henoch-Schonlein vasculitis was made. This complication, although rare, is the most common vasculitis related to immunization. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S14138670183056
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http://dx.doi.org/10.1016/j.bjid.2018.09.004DOI Listing
January 2019
23 Reads

Clinical significance of serum and mesangial galactose-deficient IgA1 in patients with IgA nephropathy.

PLoS One 2018 2;13(11):e0206865. Epub 2018 Nov 2.

Division of Nephrology, Department of Medicine, Showa University School of Medicine, Tokyo, Japan.

Introduction: Galactose-deficient IgA1 (Gd-IgA1) is a critical pathogenic factor for IgA nephropathy (IgAN), but its value as a disease-specific biomarker remains controversial. We aimed to clarify the clinical significance of Gd-IgA1 in patients with IgAN.

Methods: We retrospectively reviewed 111 patients who were diagnosed with IgAN based on the findings of renal biopsies (RB) at Showa University Hospital since 2007. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0206865PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214568PMC
April 2019
10 Reads

Multiple myeloma presenting as cutaneous leukocytoclastic vasculitis and eosinophilia disclosing a T helper type 1/T helper type 2 imbalance: a case report.

J Med Case Rep 2018 Oct 31;12(1):320. Epub 2018 Oct 31.

Division of Hematology, Japanese Red Cross Society Wakayama Medical Center, Wakayama, Japan.

Background: Multiple myeloma is a very heterogeneous disease comprising a number of genetic entities that differ from each other in their evolution, mode of presentation, response to therapy, and prognosis. Due to its more chronic nature and cumulative toxicities that patients develop from multiple lines of treatments, a number of symptoms are associated with multiple myeloma. However, the mechanisms responsible for the relationship between these symptoms and multiple myeloma currently remain unclear. Read More

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https://jmedicalcasereports.biomedcentral.com/articles/10.11
Publisher Site
http://dx.doi.org/10.1186/s13256-018-1857-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208011PMC
October 2018
8 Reads

[Expression and significance of endothelial microparticles in children with Henoch-Schönlein purpura].

Zhongguo Dang Dai Er Ke Za Zhi 2018 Oct;20(10):831-834

Children's Hospital of Zhengzhou University/Children's Hospital of Henan Province/Zhengzhou Children's Hospital/Zhengzhou Children's Critical Medical Key Laboratory, Zhengzhou 450000, China.

Objective: To study the expression and significance of endothelial microparticles (EMPs) in children with Henoch-Schönlein purpura (HSP).

Methods: A total of 100 previously untreated children with HSP were classified to Henoch-Schönlein purpura nephritis (HSPN) group (n=40) and non-nephritis group (n=60). Thirty healthy children who underwent physical examination were enrolled as control group. Read More

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October 2018
2 Reads

[Role of Th17 Cells, Interleukin-17 and Matrix Metalloproteinase-13 in Pathogenesis of Henoch-Schonlein Purpura].

Zhongguo Shi Yan Xue Ye Xue Za Zhi 2018 Oct;26(5):1502-1506

Department of Hematology, Chaohu Hospital of Anhui Medical University, Chaohu 238001, Anhui Province, China.E-mail: xhl1999cn

Objective: To explore the immunopathogenesis of Henoch-Schonlein purpara (HSP) by detecting the levels of Th17 cells, IL-17 and matrix metallo proteinase-13 (MMP-13) in peripheral blood and the expression of IL-17 in skin lesions at acate phase of HSP.

Methods: Th17 cell ratio in peripheral blood of HSP group and healthy control group was defected by flow cytometry, the plasma levels of IL-17 and MMP-13 in HSP group and healthy control group were defected by ELISA, and expression level of IL-17 in skin lesion of HSP group and skin tissue of healthy control group was deternined by: immunohistochemistry method.

Results: the ratio of Th17 cells in periphral blood of HSP group (1. Read More

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http://dx.doi.org/10.7534/j.issn.1009-2137.2018.05.041DOI Listing
October 2018

Effect of Montmorillonite powder on intestinal mucosal barrier in children with abdominal Henoch-Schonlein purpura: A randomized controlled study.

Medicine (Baltimore) 2018 Sep;97(39):e12577

Open Laboratory, West China Institute for Women's and Children's Health, Chengdu, Sichuan Province, China.

Background: Our previous studies found that intestinal barrier function has been changed in children with abdominal Henoch-Schonlein purpura (HSP). Montmorillonite has been shown to be protective for digestive tract mucosa.

Objective: The present study aimed to investigate whether Montmorillonite powder could improve the intestinal mucosal barrier function in children with abdominal HSP. Read More

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http://Insights.ovid.com/crossref?an=00005792-201809280-0008
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http://dx.doi.org/10.1097/MD.0000000000012577DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181592PMC
September 2018
7 Reads

Risk factors for renal involvement and severe kidney disease in 2731 Chinese children with Henoch-Schönlein purpura: A retrospective study.

Medicine (Baltimore) 2018 Sep;97(38):e12520

Department of Pediatrics.

To identify the risk factors for developing renal involvement and severe kidney disease in Chinese childhood Henoch-Schönlein purpura (HSP) patients.This was a retrospective study of 2731 children with HSP diagnosed between 2012 and 2015. We analyzed their demographic data, clinical manifestations, and laboratory tests retrospectively. Read More

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http://dx.doi.org/10.1097/MD.0000000000012520DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160025PMC
September 2018
11 Reads

Analysis of seasonal tendencies in pediatric Henoch-Schönlein purpura and comparison with outbreak of infectious diseases.

Medicine (Baltimore) 2018 Sep;97(36):e12217

Department of Pediatrics.

Henoch-Schönlein purpura (HSP) is one of the most common vasculitis in children. This study was aimed at identifying seasonal trends and epidemiologic features of pediatric HSP patients through public data to analyze the correlation of HSP and prevalence of a specific respiratory or enteric virus.We extracted information on pediatric HSP patients categorized into 4 age groups and data on 8 respiratory and 4 enteric viruses were extracted from national data. Read More

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http://Insights.ovid.com/crossref?an=00005792-201809070-0008
Publisher Site
http://dx.doi.org/10.1097/MD.0000000000012217DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6133644PMC
September 2018
3 Reads

A case of Henoch-Schonlein Purpura with dilated coronary arteries.

Pediatr Rheumatol Online J 2018 Sep 4;16(1):54. Epub 2018 Sep 4.

Department of Pediatric Rheumatology, Children's Hospital Colorado, 13123 East 16th Avenue, B311, Aurora, CO, 80045, USA.

Background: Henoch-Schonlein Purpura (HSP) is one of the most common vasculitides of childhood, with 10-20 cases per 100,000 children. It frequently occurs following an infectious trigger and involves IgA and C3 deposition in small vessel walls. HSP is characterized by palpable purpura plus IgA deposition on biopsy, arthritis/arthralgia, renal involvement (hematuria and/or proteinuria), and/or abdominal pain. Read More

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https://ped-rheum.biomedcentral.com/articles/10.1186/s12969-
Publisher Site
http://dx.doi.org/10.1186/s12969-018-0270-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123917PMC
September 2018
23 Reads

Ulcerative colitis in an adult patient mimicking Henoch-Schönlein purpura: A case report.

Medicine (Baltimore) 2018 Aug;97(35):e12036

Rationale: Ulcerative colitis (UC) is one of the chronic inflammatory diseases of the intestinal tract. UC being misdiagnosed as Henoch-Schönlein purpura (HSP) in the elderly has seldom been reported about.

Patient Concerns: A 64-year-old man was admitted to the hospital with petechiae and palpable purpura in lower limbs and abdominal pain for about 1 month. Read More

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http://dx.doi.org/10.1097/MD.0000000000012036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393117PMC
August 2018
9 Reads

Significance of glomerular fibrinogen deposition in children with Henoch-Schönlein purpura nephritis.

Ital J Pediatr 2018 Aug 16;44(1):97. Epub 2018 Aug 16.

Department of Pathology, Soochow University Affiliated Children's Hospital, Suzhou, Jiangsu, China.

Background: Henoch-Schönlein purpura nephritis (HSPN) is the most common pediatric secondary glomerular disease. This study aimed to investigate the significance of glomerular fibrinogen (Fib) deposition in children with HSPN.

Methods: Eighty-two patients with HSPN were enrolled retrospectively at the Children's Hospital of Soochow University from January 2015 to March 2017. Read More

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http://dx.doi.org/10.1186/s13052-018-0538-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097424PMC
August 2018
12 Reads

Adult Henolch-Schonlein purpura: multiorgan failure in the setting of a purpuric rash.

BMJ Case Rep 2018 Aug 9;2018. Epub 2018 Aug 9.

Internal Medicine, University of Tennessee at Chattanooga, College of Health Education and Professional Studies, Chattanooga, Tennessee, USA.

We report a 66-year-old man with a history of congestive heart failure, atrial fibrillation on warfarin therapy and chronic kidney disease that presented with acute dyspnoea. He had multiple palpable purpuric lesions on his bilateral lower extremities. Laboratory findings supported acute anaemia with no obvious bleeding source, supratherapeutic international normalised ratio and acute on chronic kidney injury. Read More

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http://dx.doi.org/10.1136/bcr-2018-224816DOI Listing
August 2018
6 Reads

Resolution of sinus bradycardia, high-grade heart block, and left ventricular systolic dysfunction with rituximab therapy in Henoch-Schonlein purpura.

Intern Med J 2018 07;48(7):868-871

Albany Medical Center, Albany, New York, USA.

Henoch-Schonlein purpura (HSP) is a rare, typically self-limited, multi-organ vasculitis. Cardiac involvement with HSP carries high morbidity and mortality, thus requiring early aggressive immunosuppressive therapy. We report a case of HSP complicated with acute systolic left ventricular (LV) dysfunction, symptomatic sinus bradycardia and high-grade atrio-ventricular (AV) heart block. Read More

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http://dx.doi.org/10.1111/imj.13948DOI Listing
July 2018
4 Reads

Neutrophil-to-lymphocyte ratio to predict gastrointestinal bleeding in Henoch: Schönlein purpura.

Pediatr Int 2018 Sep 5;60(9):791-795. Epub 2018 Sep 5.

Department of Pediatrics, Chonnam National University Hospital, Gwangju, Korea.

Background: Henoch-Schönlein purpura (HSP) is a common form of vasculitis in children. It typically involves small vessels of the skin, the gastrointestinal (GI) tract, joints, and kidneys. GI involvement is the most severe short-term complication and GI bleeding is a major complication of HSP, but there is no established predictive marker of GI bleeding. Read More

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http://dx.doi.org/10.1111/ped.13652DOI Listing
September 2018
17 Reads

What We Know about Henoch-Schönlein Purpura in Children up to Date?

Authors:
Hye Ran Yang

J Korean Med Sci 2018 06 7;33(25):e199. Epub 2018 Jun 7.

Division of Pediatric Gastroenterology and Hepatology, Department of Pediatrics, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.

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http://dx.doi.org/10.3346/jkms.2018.33.e199DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6000601PMC
June 2018
6 Reads

Ten-year Nationwide Population-based Survey on the Characteristics of Children with Henoch-Schӧnlein Purpura in Korea.

J Korean Med Sci 2018 Jun 14;33(25):e174. Epub 2018 May 14.

Department of Pediatrics, Inje University College of Medicine, Seoul, Korea.

Background: Henoch-Schӧnlein purpura (HSP) is a common vasculitis of childhood. Though HSP is usually self-limiting, severe complications can occur. The management for this condition has not been established yet. Read More

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http://dx.doi.org/10.3346/jkms.2018.33.e174DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6000599PMC
June 2018
5 Reads

The Spectrum of Biopsy-Proven Glomerular Diseases among Children in China: A National, Cross-Sectional Survey.

Clin J Am Soc Nephrol 2018 Jul 18;13(7):1047-1054. Epub 2018 Jun 18.

The National Clinical Research Center for Kidney Disease, State Key Laboratory of Organ Failure Research, Renal Division, Nanfang Hospital and

Background And Objectives: High-quality epidemiologic data on the spectrum of biopsy-proven glomerular diseases among children are limited. This study aimed to determine the profile of and temporal change in biopsy-proven pediatric glomerular diseases in China.

Design, Setting, Participants, & Measurements: We previously conducted a nationwide kidney biopsy survey including 71,151 patients over an 11-year period from January 2004 to December 2014. Read More

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http://dx.doi.org/10.2215/CJN.11461017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032591PMC
July 2018
55 Reads

Comparing immunoglobulin A vasculitis (Henoch-Schönlein purpura) in children and adults: a single-centre study from Turkey.

Scand J Rheumatol 2018 Nov 18;47(6):481-486. Epub 2018 Jun 18.

a Division of Rheumatology, Department of Pediatrics , Hacettepe University Faculty of Medicine , Ankara , Turkey.

Objective: Immunoglobulin A vasculitis/Henoch-Schönlein purpura (IgAV/HSP) is a systemic vasculitis involving small vessels with the deposition of immune complexes containing IgA. It is the most common primary systemic vasculitis of childhood and is much less common in adults. Our aim was to investigate the differences and similarities between adult and paediatric patients with IgAV/HSP. Read More

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http://dx.doi.org/10.1080/03009742.2018.1448111DOI Listing
November 2018
11 Reads

Chinese herbal medicine for the treatment of Henoch-Schönlein purpura nephritis in children: A prospective cohort study protocol.

Medicine (Baltimore) 2018 Jun;97(24):e11064

Affiliated Hospital of Liaoning University of Traditional Chinese Medicine.

Introduction: Henoch-Schönlein purpura nephritis (HSPN) involves the renal impairment of Henoch-Schönlein purpura and can easily relapse into life-threatening late nephropathy in severe cases. Although there is a lack of validated evidence for its effectiveness, Chinese herbal medicine (CHM) is one of the most commonly used methods in China to treat HSPN. It is thus need to report the protocol of a prospective cohort trial using CHM to investigate the effectiveness, safety and advantages for children with HSPN. Read More

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http://dx.doi.org/10.1097/MD.0000000000011064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024032PMC
June 2018
16 Reads
5.720 Impact Factor

Reply to the letter: "Can such an animal model truly represent Henoch-Schönlein purpura?"

Arch Dermatol Res 2018 08 1;310(6):535-536. Epub 2018 Jun 1.

Key Laboratory of Human Diseases Comparative Medicine, Ministry of Health, Beijing, People's Republic of China.

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http://dx.doi.org/10.1007/s00403-018-1839-3DOI Listing
August 2018
8 Reads

Unusual presentation of Henöch-Schonlein purpura.

BMJ Case Rep 2018 May 30;2018. Epub 2018 May 30.

Bedford Hospital NHS Trust, Bedford, UK.

We present a rare case of a 4-year-old boy with newly diagnosed Henöch-Schonlein purpura (HSP) affecting the scrotum and penis. The patient presented to the emergency department with palpable purpura symmetrically distributed over the lower limbs. This was associated with arthritis of the right knee, abdominal pain and scrotal swelling. Read More

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http://dx.doi.org/10.1136/bcr-2017-220129DOI Listing
May 2018
6 Reads

[Clinical effect and mechanism of hemoperfusion in treatment of children with severe abdominal Henoch-Schönlein purpura].

Zhongguo Dang Dai Er Ke Za Zhi 2018 May;20(5):378-382

Department of Nephrology, Anhui Provincial Children′s Hospital, Hefei 230051, China.

Objective: To study the clinical effect and mechanism of hemoperfusion (HP) in the treatment of children with severe abdominal Henoch-Schönlein purpura (HSP).

Methods: A total of 24 children with severe abdominal HSP were divided into two groups: conventional treatment and HP (n=12 each). Ten healthy children who underwent physical examination were enrolled as the control group. Read More

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May 2018
9 Reads

Henoch-Schönlein purpura with acute pancreatitis: analysis of 13 cases.

BMC Pediatr 2018 05 11;18(1):159. Epub 2018 May 11.

Department of Pediatrics, First Affiliated Hospital of Anhui Medical University, 19th Floor of Medicine and Medical Tech Building, 218 Jixi Road, Hefei, 230022, Anhui, China.

Background: Henoch-Schönlein purpura is a common small vessel vasculitis in children. Acute pancreatitis rarely presents as a complication of Henoch-Schönlein purpura and has not been well characterized.

Methods: We retrospectively reviewed 13 cases of Henoch-Schönlein purpura with acute pancreatitis among 3212 patients who attended our hospital between January 2003 and June 2016 and analyzed their clinical characteristics, laboratory findings, imaging findings, treatment and overall prognosis. Read More

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https://bmcpediatr.biomedcentral.com/articles/10.1186/s12887
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http://dx.doi.org/10.1186/s12887-018-1142-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5948829PMC
May 2018
4 Reads

Hemorrhagic bullous lesions in Henoch-Schönlein purpura: a case report and review of the literature.

BMC Pediatr 2018 05 10;18(1):157. Epub 2018 May 10.

Division of Pediatric Allergy, Immunology and Rheumatology, Department of Pediatrics, Kaohsiung Veterans General Hospital, No. 386, Dazhong 1st Road, Zuoying District, Kaohsiung City, 813, Taiwan.

Background: Henoch-Schönlein purpura (HSP) is a common vasculitis in childhood characterized by purpura, arthritis, abdominal pain and renal involvement. However, bullous HSP is a rare cutaneous manifestation, and a few cases have been reported.

Case Presentation: Herein, we report a 15-year-old male with bullous HSP who presented with severe abdominal pain and hemorrhagic bullous lesions over his lower extremities. Read More

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http://dx.doi.org/10.1186/s12887-018-1117-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944150PMC
May 2018
4 Reads

Distinct characteristics and outcomes in elderly-onset IgA vasculitis (Henoch-Schönlein purpura) with nephritis: Nationwide cohort study of data from the Japan Renal Biopsy Registry (J-RBR).

PLoS One 2018 8;13(5):e0196955. Epub 2018 May 8.

Division of Nephrology, Kanazawa Medical University School of Medicine, Ishikawa, Japan.

Background: The clinical presentation and prognosis of adult and elderly patients with IgA vasculitis (Henoch-Schönlein purpura) accompanied by nephritis (IgAV-N) have not been investigated in detail. We therefore surveyed the features and outcomes of IgAV-N based on nationwide data derived from the Japan Renal Biopsy Registry (J-RBR).

Methods: This multi-center cohort study compared the clinicopathological parameters at diagnosis, initial therapies and outcomes between 106 adult (age 19-64 years) and 46 elderly (≥65 years) patients with IgAV-N who were registered in the J-RBR between 2007 and 2012. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0196955PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940189PMC
August 2018
7 Reads

Association between the functional PTPN22 G788A (R263Q) polymorphism and susceptibility to autoimmune diseases: A meta-analysis.

Cell Mol Biol (Noisy-le-grand) 2018 Apr 30;64(5):46-51. Epub 2018 Apr 30.

Division of Rheumatology, Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.

This study explored whether the functional protein tyrosine phosphatase nonreceptor 22 (PTPN22) G788A (R263Q) polymorphism is associated with susceptibility to autoimmune diseases. A meta-analysis was conducted using 23 comparative studies with a total of 16,719 patients and 17,783 controls. The meta-analysis showed an association between the A allele of the PTPN22 G788A polymorphism and decreased risk of autoimmune diseases in all subjects (p < 0. Read More

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April 2018
3 Reads

Role of Direct Immunofluorescence in Cutaneous Small-Vessel Vasculitis: Experience From a Tertiary Center.

Am J Dermatopathol 2018 Sep;40(9):661-666

Departments of Histopathology.

Skin is commonly affected by vasculitic process and often subjected to biopsy. Cutaneous vasculitis can be either primary or part of a systemic vasculitic process. This study was conducted to evaluate the diagnostic utility of direct immunofluorescence (DIF) in determination of etiology of cutaneous vasculitis. Read More

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http://Insights.ovid.com/crossref?an=00000372-201809000-0000
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http://dx.doi.org/10.1097/DAD.0000000000001170DOI Listing
September 2018
28 Reads
1.430 Impact Factor

Bullous Henoch-Schönlein purpura. Case report.

Rev Chil Pediatr 2018 Feb;89(1):103-106

Facultad de Medicina, CAS, UDD, Santiago, Chile.

Henoch-Schönlein purpura (HSP) or IgA Vasculitis is the most common childhood vasculitis. The classic tetrad of signs and symptoms include palpable purpura, arthralgia, abdominal pain and renal disease. The occurrence of hemorrhagic bullae in children with HSP is rarely encountered. Read More

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http://dx.doi.org/10.4067/S0370-41062018000100103DOI Listing
February 2018
2 Reads

Associations of chronic urticaria with atopic and autoimmune comorbidities: a nationwide population-based study.

Int J Dermatol 2018 Jul 16;57(7):822-829. Epub 2018 Apr 16.

Department of Health Services Administration, China Medical University, Taichung, Taiwan.

Background: Most cases of chronic urticaria (CU) are idiopathic. Circumstantial evidence suggests that some CU cases have an autoimmune pathogenesis. Previous research indicates that a substantial percentage of patients with CU have an atopic background. Read More

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http://dx.doi.org/10.1111/ijd.14000DOI Listing
July 2018
10 Reads

Incidence and risk factors for recurrent Henoch-Schönlein purpura in children from a 16-year nationwide database.

Pediatr Rheumatol Online J 2018 Apr 16;16(1):25. Epub 2018 Apr 16.

Department of Medicine, Mackay Medical College, No.45, Minsheng Rd., Tamsui Dist., New Taipei City, 25160, Taiwan.

Background: The recurrence rate of Henoch-Schönlein purpura (HSP) is 2.7%-30%, with varied average intervals between the first and second episodes. Few studies have explored the incidence and risk factors for recurrent HSP. Read More

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http://dx.doi.org/10.1186/s12969-018-0247-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902957PMC
April 2018
16 Reads