6,743 results match your criteria Hemorrhoids


Revealing the Mechanism of "Huai Hua San" in the Treatment of Ulcerative Colitis based on Network Pharmacology and Experimental Study.

J Ethnopharmacol 2021 Jun 9:114321. Epub 2021 Jun 9.

Faculty of Pharmacy, Hubei University of Chinese Medicine, Wuhan, 430065, China; Key Laboratory of Traditional Chinese Medicine Resources and Chemistry of Hubei Province, Wuhan, 430065, China; Collaborative Innovation Center of Traditional Chinese Medicine of New Products for Geriatrics Hubei Province, Wuhan, 430065, China. Electronic address:

Ethnopharmacological Relevance: "Huai Hua San" (HHS) is one of the first hundred ancient classic prescriptions drugs, which is commonly used to treat hemorrhoids, colitis, and other symptoms of wind heat in stool. However, the potential molecular mechanism of action of this substance remains unclear.

Aims Of The Study: In this study, we explored the active compounds of HHS for the treatment of ulcerative colitis (UC), predicted the potential targets of the drug, and studied its mechanism of action through network pharmacology via in vitro and in vivo experiments. Read More

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Rectal perforation and perirectal abscess following stapled hemorrhoidectomy for prolapsed hemorrhoids successfully managed with Endo-SPONGE endoluminal vacuum-assisted wound closure system.

Ann Coloproctol 2021 Jun 9. Epub 2021 Jun 9.

Department of Surgery, School of Medicine, University of Perugia, Perugia, Italy.

Active drains, which work by negative pressure, are commonly used to drain closed airtight wounds. Higher negative pressure is used in vacuum-assisted wound closure dressings. Gastrointestinal leaks may be difficult to treat by surgical approach because of their association with high morbidity and mortality. Read More

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Efficacy and safety of acupoint catgut embedding in treating postoperative pain of mixed hemorrhoids: A randomized controlled trial protocol.

Medicine (Baltimore) 2021 May;100(19):e25948

Department of General Surgery, Tianjin TEDA Hospital.

Background: Pain is a common complication after mixed hemorrhoids, which seriously affects the recovery of patients and prolongs the length of hospital stay. Acupoint catgut embedding has advantages in improving a variety of acute and chronic pain diseases, but there is still a lack of rigorous randomized controlled studies to verify its efficacy and safety in the treatment of postoperative pain of mixed hemorrhoids. Therefore, the purpose of this randomized controlled trial is to evaluate the clinical efficacy of acupoint catgut embedding in the treatment of postoperative pain of mixed hemorrhoids. Read More

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An update on surgical treatment of hemorrhoidal disease: a systematic review and meta-analysis.

Int J Colorectal Dis 2021 Jun 8. Epub 2021 Jun 8.

Department of General Surgery, Department of Colon and Rectal Surgery, Temple University Lewis Katz School of Medicine, 3401 N. Broad St., Zone C, 4th Floor, Philadelphia, PA, 19140, USA.

Background: Pathologic hemorrhoids are common among adults age 45-65. Hemorrhoids are characterized as internal or external, and grades 1-4 based on severity. The type and grade dictate treatment, with surgical treatment reserved for grades 3/4. Read More

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Lithotomy versus Prone Position for Perianal Surgery: A Randomized Controlled Trial.

Ann Coloproctol 2021 Jun 7. Epub 2021 Jun 7.

Department of General Surgery, All India Institute of Medical Sciences (AIIMS) Bhubaneswar, Bhubaneswar, India.

Purpose: Studies objectively comparing lithotomy and prone positions regarding surgeon comfort, ergonomics, patient comfort, and position related complications are scarce.

Methods: The patients posted for surgery of either fistula in ano, hemorrhoids, or were included in this study. Subjective Mental Effort Questionnaire (SMEQ) and Local Experienced Discomfort (LED) scale were used to score the level of mental and physical stress among the operating surgeon, assistants, and the scrub nurse. Read More

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Formulation of Suppositories of Alum Produced from Bauxite Waste in Ghana for the Treatment of Hemorrhoid.

ScientificWorldJournal 2021 12;2021:6667562. Epub 2021 May 12.

Department of Civil Engineering, College of Engineering, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.

The study sought to formulate and evaluate suppositories using a locally produced brand of alum (Aw) obtained from bauxite waste generated at Awaso bauxite mine in the Western-North region of Ghana, for use in the treatment of hemorrhoids. The suppositories were formulated using shea butter modified, respectively, with amounts of beeswax and theobroma oil. In another development, theobroma oil was modified with different concentrations of beeswax. Read More

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Hemorrhoids in Obsessive-Compulsive Disorder.

Prim Care Companion CNS Disord 2021 Jun 3;23(3). Epub 2021 Jun 3.

Department of Psychiatry, Iqraa International Hospital and Research Centre, Calicut, Kerala, India.

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Doppler-guided hemorrhoidal artery ligation with suture mucopexy compared with LigaSure™-assisted pile excision for the treatment of grade III hemorrhoids: a prospective randomized controlled trial.

Minerva Surg 2021 Jun;76(3):264-270

Emergency Department, Puzi Hospital, Taiwan, China.

Background: Doppler-guided hemorrhoid artery ligation and stapled hemorrhoidopexy have been used in surgical practices to avoid post-hemorrhoidectomy pain. Our study compared Doppler-guided hemorrhoid artery ligation with suture mucopexy (DGHAL-SM) and ligature-assisted pile excision (LAP) for greater than three grades of internal hemorrhoids.

Methods: Eighty patients with greater than 3 grades of internal hemorrhoids were selected (age range: 20-28 years; average age: 23 years) between January and June 2015. Read More

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Analysis of early and late maternal complications associated with delivery using propensity score.

Rev Bras Epidemiol 2021 26;24:e210027. Epub 2021 May 26.

Epidemiological Research Center, Post-Graduation Program in Epidemiology, Universidade Federal de Pelotas - Pelotas (RS), Brazil.

Objective: To analyze early and late maternal complications associated with the mode of delivery in a birth cohort in Brazil, using the propensity score technique for analysis.

Methods: This is a prospective cohort study, using data from the Pelotas Birth Cohort, RS, 2004. A total of 4,189 women were included and a descriptive analysis of the data and subsequent calculation of the propensity and pairing score of vaginal delivery women and cesarean delivery women with similar scores (1,366 pairs). Read More

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The Potential Link between Episodes of Diverticulitis or Hemorrhoidal Proctitis and Diets with Selected Plant Foods: A Case-Control Study.

Nutrients 2021 May 24;13(6). Epub 2021 May 24.

Department of Preventive Medicine and Public Health, University of Valencia, 46010 Valencia, Spain.

Diverticulitis and hemorrhoidal proctitis in the population are significant public health problems. We studied the potential association between the intake of certain plant foods and diverticulitis or hemorrhoidal episodes through a case-control study including 410 cases and 401 controls. We used a semiquantitative food frequency questionnaire. Read More

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Benefits of flavonoid and metronidazole use after excisional hemorrhoidectomy: a randomized double-blind clinical trial.

Tech Coloproctol 2021 May 31. Epub 2021 May 31.

Division of Coloproctology, Felicio Rocho Hospital, Belo Horizonte, Brazil.

Background: Excisional hemorrhoidectomy remains the most effective treatment for a significant group of patients with hemorrhoids, despite the potential for postoperative pain. The purpose of this study was to evaluate the effects of flavonoid and metronidazole use in the postoperative period on patients undergoing excisional hemorrhoidectomy.

Methods: A double-blind randomized clinical study was performed. Read More

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Anorectal Melanoma Misdiagnosed as Hemorrhoids: A Case Report and Review of the Literature.

J Clin Aesthet Dermatol 2021 Apr 1;14(4):32-35. Epub 2021 Apr 1.

Drs. Edelman, Brown, and Rishi Gandhi are with the Division of Dermatology at the University of Louisville School of Medicine in Louisville, Kentucky.

Anorectal melanoma is a rare and aggressive malignant neoplasm with an indolent course, manifesting with nonspecific symptoms and a poor prognosis. We present a case of anorectal melanoma that was initially treated as hemorrhoids and correctly diagnosed after lower gastrointestinal endoscopy. We also present the latest findings in the literature about anorectal melanomas and discuss updates about treatment options and management. Read More

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Galla Chinensis, a Traditional Chinese Medicine: Comprehensive review of botany, traditional uses, chemical composition, pharmacology and toxicology.

J Ethnopharmacol 2021 May 27:114247. Epub 2021 May 27.

State Key Laboratory of Southwestern Chinese Medicine Resources, No.1166, Liutai Road, Wenjiang District, Chengdu, 611137, China. Electronic address:

Ethnopharmacological Relevance: Galla chinensis (GC), a traditional Chinese medicine (TCM), has a wide range of pharmacological properties which have been widely used for more than 1400 years. Based on shape, GC is divided into two groups: jiaobei and dubei. It is a bitter, sour, cold and astringent substance which is usually used for treating diarrhea, constipation, bleeding, cough, vomiting, sweating, hemorrhoids, and anal and uterine prolapse. Read More

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Efficacy of Ruiyun procedure for hemorrhoids combined simplified Milligan-Morgan hemorrhoidectomy with dentate line-sparing in treating grade III/IV hemorrhoids: a retrospective study.

BMC Surg 2021 May 20;21(1):251. Epub 2021 May 20.

Department of Proctology, China-Japan Friendship Hospital, No. 2 Yinghua East Street, Chaoyang District, Beijing, 100029, China.

Background: Hemorrhoids are common. Hemorrhoidectomy should typically be offered to patients whose symptoms result from external hemorrhoids or combined internal and external hemorrhoids with prolapse (grades III/IV). However, none of the currently used surgical methods could be considered an ideal surgical option that is effective, safe, and painless. Read More

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A NEW APPROACH FOR HEMORRHOID DISEASE: SELECTIVE DEARTERIALIZATION AND MUCOPEXY WITHOUT DOPPLER GUIDANCE.

Arq Bras Cir Dig 2021 14;34(1):e1560. Epub 2021 May 14.

Digestive and Colorectal Surgery Division, Department of Gastroenterology, Hospital das Clínicas, University of São Paulo School of Medicine, São Paulo, Brazil.

Background: The surgical procedure: three dearterializations and three mucopexies.Transanal hemorrhoidal dearterialization (THD) is safe and effective minimally invasive treatment for hemorrhoidal disease, but reports regarding recurrence and postoperative complications (pain and tenesmus) vary significantly.

Aim: To evaluate if selective dearterialization and mucopexy at the symptomatic hemorrhoid only, without Doppler guidance, achieves adequate control of the prolapse and bleeding and if postoperative morbidity is reduced with this technique. Read More

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The REALISE score: a new statistically validated scoring system to assess the severity of anal fissures.

Tech Coloproctol 2021 May 13. Epub 2021 May 13.

Surgical Unit "M. Rubino" Department of Emergency and Organ Transplantation, University Aldo Moro of Bari, Bari, Italy.

Background: Anal fissure (AF) is a common, painful disease that strongly affects patients' quality of life, however, no scoring system to assess the severity of AF is available in the literature. The aim of this study was to set up and validate a reliable scoring system to quantify the severity of AF, to be used in prospective trials comparing the efficacy and the outcomes of surgical or medical treatments.

Methods: The study was conducted on patients with acute or chronic AF and a control group in a tertiary centre for coloproctology in June 2020-September 2020. Read More

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[Discussion on traditional Chinese medicine properties of Myrtus communis leaves based on literature analysis and Chinese medicine theory].

Zhongguo Zhong Yao Za Zhi 2021 Apr;46(8):1935-1942

School of Chinese Materia Medica, Beijing University of Chinese Medicine Beijing 100029, China.

Myrtus communis is a traditional medicinal aromatic plant in the Mediterranean. At present, the plant has been introduced and cultivated in the southern part of China, and it is mostly used for ornamental or cosmetic purposes. Based on literature analysis and the theory of Chinese medicine, we discussed the medicinal parts and properties of M. Read More

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Outpatient Transradial Emborrhoid Technique: A Pilot Study.

Cardiovasc Intervent Radiol 2021 May 11. Epub 2021 May 11.

Dipartimento Di Diagnostica Per Immagini, Radioterapia Oncologica Ed Ematologia - Istituto Di Radiologia, Fondazione Policlinico Universitario A. Gemelli IRCCS, L.go A Gemelli 8, 00168, Rome, Italy.

Purpose: To determine whether outpatient transradial emborrhoid technique can be performed safely and effectively in the treatment of symptomatic hemorrhoids.

Materials And Methods: The transradial emborrhoid technique was used to treat 12 patients with symptomatic hemorrhoids in an outpatient setting during a 4-month period. After percutaneous catheterization of the left radial artery, a 5-Fr sheath was introduced to catheterize the inferior mesenteric artery and a microcatheter was advanced into the branches of the superior rectal artery for embolization with 0. Read More

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Catheter directed haemorrhoidal de-arterialization technique for the management of haemorrhoids: a meta-analysis of the clinical evidence.

J Vasc Interv Radiol 2021 May 7. Epub 2021 May 7.

Vascular and oncologic Interventional Radiology Department at the Hôpital Européen Georges Pompidou, France.

Purpose: To assess the efficacy and safety of catheter directed hemorrhoidal de-arterialization (CDHD) technique for the management of hemorrhoidal bleeding METHODS: A systematic review and meta-analysis of the Pubmed, Cochrane and Scopus databases was conducted according to the PRISMA guidelines. Clinical studies reporting on CDHD for rectal bleeding were analyzed.

Results: 14 studies (N=362) were identified. Read More

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Improvement in quality of life among Sri Lankan patients with haemorrhoids after invasive treatment: a longitudinal observational study.

BJS Open 2021 03;5(2)

Duke-NUS Medical School, Singapore.

Background: Haemorrhoids is a common chronic disease that can significantly impact patients' quality of life. Yet, few studies have evaluated health-related quality of life (HRQoL) of patients with haemorrhoids before and after treatment. This study investigated the HRQoL of patients with haemorrhoids before and after treatment and the change in HRQoL from baseline. Read More

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LigaSure Hemorrhoidectomy and Current Guidelines on Large Hemorrhoids.

Dis Colon Rectum 2021 Jun;64(6):e380

Department of General and Laparoscopic Surgery, Sir Ganga Ram Hospital, New Delhi, India.

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Integrating Ethnobotany, Phytochemistry, and Pharmacology of and : What Predictions can be Made for the European Smoketree?

Front Pharmacol 2021 19;12:662852. Epub 2021 Apr 19.

Department of Toxicology, Faculty of Pharmacy, "Victor Babes" University of Medicine and Pharmacy, Timisoara, Romania.

The smoketree () is a historically known medicinal plant from Southeast Europe. Its ethnomedicinal use in skin and mucosal lesions is commonly accepted across countries. Other utilizations reported locally include fever reduction, cardiac diseases, hypertension, urinary diseases, cough, asthma, hemorrhoids, diabetes, numbness of arm, liver disease, and cancer. Read More

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Clinical study of herbal mixture "Diding Oral Medicine" as an alternative to preventative antibiotics in perioperative hemorrhoids: A CARE-compliant article.

Medicine (Baltimore) 2021 May;100(18):e25661

Department of Science and Education, Zigong Hospital of Traditional Chinese Medicine, Zigong, China.

Abstract: To study the clinical effects of Diding Oral Medicine as an alternative to preventative antibiotics in perioperative hemorrhoids.From August 2017 to February 2018, a total of 214 patients who were treated with external exfoliation and internal ligation of mixed hemorrhoids in our hospital were divided into the control group and experimental group by way of stratified random (107 cases in each group). Patients in the control group were given antibiotics preventatively before operation, while patients in the experimental group took Diding Oral Medicine before operation, and the white blood cell count, neutrophil count, wound recovery, pain score, anal bulge score, and pathogen culture of wound secretions were compared between the 2 groups. Read More

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Phytochemical properties, biological activities and medicinal use of Centaurium erythraea Rafn.

J Ethnopharmacol 2021 Aug 30;276:114171. Epub 2021 Apr 30.

Laboratory of Human Pathologies Biology, Department of Biology, Faculty of Sciences, And Genomic Center of Human Pathologies, Faculty of Medicine and Pharmacy, Mohammed V University in Rabat, Morocco. Electronic address:

Ethnopharmacological Relevance: Centaurium erythraea is an important medicinal plant in many countries, e.g. Morocco, Algeria, Italy, Spain, Portugal, and countries of Balkan Peninsula. Read More

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Micronized purified flavonoid fraction in the treatment of hemorrhoidal disease.

J Comp Eff Res 2021 Apr 30. Epub 2021 Apr 30.

State Scientific Center of Coloproctology, Ministry of Health of Russian Federation, Moscow, Russia.

Hemorrhoidal disease (HD) is common in adults. Treatment is largely conservative, although more invasive procedures may be required. Venoactive drugs such as micronized purified flavonoid fraction (MPFF) are widely used, but a recent and comprehensive review of supporting evidence is lacking. Read More

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A Prospective Study on the Efficacy of Two Different Phlebotonic Therapies as a Bridge to Surgery in Patients with Advanced Hemorrhoidal Disease.

J Clin Med 2021 Apr 7;10(8). Epub 2021 Apr 7.

Proctology Unit, Fondazione Policlinico Universitario "A. Gemelli" IRCCS, Largo A. Gemelli, 8, 00168 Rome, Italy.

The aims of this study were to evaluate the efficacy of two different phlebotonic therapies, preoperatively administered in advanced hemorrhoidal disease (HD) patients with recommendation for surgery, and to assess patient satisfaction after treatment. In this prospective observational study, 100 patients were preoperatively treated either with micronized purified flavonoid fraction (group A) or sublingual nano-emulsion flavonoid (group B). HD symptoms, local inflammation signs and patients' satisfaction were evaluated at baseline visit (T0), after 4 weeks of therapy (T1) and 8 weeks after its discontinuation (T2). Read More

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Metastatic anorectal malignant melanoma causing ileocaecal junction obstruction due to contiguous spread.

BMJ Case Rep 2021 Apr 28;14(4). Epub 2021 Apr 28.

General Surgery, BYL Nair Charitable Hospital, Mumbai, Maharashtra, India

Malignant melanoma of the anal canal is a rare and aggressive tumour associated with significant mortality. Early diagnosis and early curative surgical resection have shown to offer a survival advantage. We present a case of 53-year-old woman, who was accidentally diagnosed to have a localised lesion of malignant melanoma of the anal canal on histopathology report of the specimen of haemorrhoidectomy done for thrombosed external haemorrhoids. Read More

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