6,263 results match your criteria Hemorrhoids


Allergic Contact Dermatitis and Autoeczematization to Proctosedyl® Cream and Proctomyxin® Cream.

Case Rep Dermatol 2018 Sep-Dec;10(3):238-246. Epub 2018 Oct 24.

Department of Dermatology, University of Ottawa, Ottawa, Ontario, Canada.

Proctosedyl® and Proctomyxin® are two commonly prescribed hemorrhoid therapies. Their topical application to the perianal region may be complicated by a local allergic contact dermatitis and subsequent autoeczematization reaction. We present three cases of an autoeczematization (ID) reaction to varying topical allergens found in Proctosedyl®/Proctomyxin®. Read More

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October 2018
1 Read

Skin anti-inflammatory activity of rose petal extract () through reduction of MAPK signaling pathway.

Food Sci Nutr 2018 Nov 25;6(8):2560-2567. Epub 2018 Oct 25.

Korea Food Research Institute Wanju-gun Korea.

The aim of this study was to investigate the skin anti-inflammatory activity of rose petal extract (RPE) and the mechanisms underlying this phenomenon. Recently, flowers have been considered as dietary resources owing to their biological activities, such as inhibition of nephritis and hemorrhoids. The plant exerts various biological functions, including antioxidant and anti-microbiological activities. Read More

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November 2018
4 Reads

Effects of Stapled Hemorrhoidopexy on Anorectal Function: A Prospective Randomized Controlled Trial.

Iran J Med Sci 2018 Nov;43(6):581-586

Colorectal Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.

Background: Stapled hemorrhoidopexy is a safe and acceptable alternative to traditional hemorrhoidectomy with shorter hospital stay, better satisfaction, and less postoperative pain. There have, however, been reports on early and late complications. Therefore, the present study was designed to assess the impact of stapled hemorrhoidopexy on anorectal function and continence. Read More

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November 2018
2 Reads

Partial Stapled Hemorrhoidopexy Versus Circumferential Stapled Hemorrhoidopexy for Grade III to IV Prolapsing Hemorrhoids: A Randomized, Noninferiority Trial.

Dis Colon Rectum 2018 Nov 26. Epub 2018 Nov 26.

Background: Long-term outcomes and efficacy of partial stapled hemorrhoidopexy are not known.

Objective: The purpose of this study was to compare the long-term clinical efficacy and safety of partial stapled hemorrhoidopexy with circumferential stapled hemorrhoidopexy.

Design: This was a parallel group, randomized, noninferiority clinical trial. Read More

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November 2018

Estimating disease burden using Internet data.

Health Informatics J 2018 Nov 29:1460458218810743. Epub 2018 Nov 29.

The University of North Carolina at Charlotte, USA; Mayo Clinic, USA.

Data on disease burden are often used for assessing population health, evaluating the effectiveness of interventions, formulating health policies, and planning future resource allocation. We investigated whether Internet usage and social media data, specifically the search volume on Google, page view count on Wikipedia, and disease mentioning frequency on Twitter, correlated with the disease burden, measured by prevalence and treatment cost, for 1633 diseases over an 11-year period. We also applied least absolute shrinkage and selection operator to predict the burden of diseases. Read More

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November 2018

Prolapsing mucosal fold: largest reported, presenting with major haemorrhage.

J Surg Case Rep 2018 Nov 22;2018(11):rjy312. Epub 2018 Nov 22.

Department of Surgery, Epworth Health, Box Hill, Victoria, Australia.

Prolapsing mucosal folds are uncommon benign colonic lesions that when inflamed may macroscopically resemble, and be confused with, an adenomatous or hyperplastic polyp. They are usually small and rarely cause symptoms. We report the case of a 55-year-old female admitted to hospital following six episodes of significant rectal bleeding. Read More

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November 2018

Bipolar radiofrequency-induced thermotherapy of haemorrhoids: a 10-year experience.

Rozhl Chir 2018 ;97(9):419-422

Introduction: Bipolar radiofrequency-induced thermotherapy of advanced stage haemorrhoid disease has been used successfully at the Atlas Hospital in Zlin for ten years. The aim of this study was to evaluate long-term outcomes of the method.

Method: RFITTH is bipolar radiofrequency-induced thermotherapy of haemorrhoidal diseases. Read More

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January 2018
3 Reads

Aerobic vaginitis in late pregnancy and outcomes of pregnancy.

Eur J Clin Microbiol Infect Dis 2018 Nov 22. Epub 2018 Nov 22.

Department of Gynecology and Obstetrics, Tianjin Medical University General Hospital, No.154 Anshan Road, Heping District, Tianjin, 300052, China.

The purpose of this study was to investigate the risk factors and pregnancy outcomes for aerobic vaginitis (AV) in late pregnancy. A total of 624 pregnant women who were treated in the perinatal unit at Tianjin Medical University General Hospital and 365 nonpregnant women who were evaluated at a health management center from January 2015 to June 2016 were recruited for this case-control study. A questionnaire covering personal hygiene habits and sociodemographic factors was administered to pregnant women to analyze risk factors for AV. Read More

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November 2018
8 Reads

Topical Analgesia with Lidocaine Plus Diclofenac Decreases Pain in Benign Anorectal Surgery: Randomized, Double-blind, and Controlled Clinical Trial.

Clin Transl Gastroenterol 2018 Nov 23;9(11):210. Epub 2018 Nov 23.

Drug Development Services, Pharmacy and Pharmaceutical Technology and Physical Chemistry Department, University of Barcelona, Barcelona, Spain.

Objective: The aim of this study is to evaluate the efficacy and safety of a topical formulation containing lidocaine plus diclofenac (CLIFE1) compared to lidocaine (CLIFE2), to decrease pain in benign anorectal surgery (BARS) to date not evaluated. More than 50% of patients undergoing BARS, especially hemorrhoidectomy, suffer from moderate and severe postoperative pain. This remains an unresolved problem that could be addressed with the new CLIFE1 topical treatment. Read More

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November 2018
3 Reads

Management of disseminated intravascular coagulation in a patient with hepatic angiosarcoma: A case report.

Medicine (Baltimore) 2018 Nov;97(47):e13321

Hematology Division, Massachusetts General Hospital, Boston, MA.

Rationale: Hepatic angiosarcoma is a rare endothelial cell tumor that may lead to concurrent consumptive coagulopathies including disseminated intravascular coagulation (DIC). This report details a multifaceted approach to managing DIC in a patient with advanced-stage hepatic angiosarcoma, which continued to progress after a brief response to taxane-based chemotherapy.

Patient Concerns: A 55-year-old man with a recent history of hemorrhoids and hemarthroses presented with acute rectal bleeding. Read More

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November 2018
8 Reads

Therapeutic Potential of : A Review on Its Traditional Uses, Phytochemistry, Pharmacology and Toxicological Aspects.

Front Pharmacol 2018 22;9:1177. Epub 2018 Oct 22.

Department of Pharmacology, School of Pharmacy and Technology Management, SVKM's NMIMS, Dhule, India.

(Cucurbitaceae), a perennial plant grows mainly in India, Southeast Asia, China, Japan, Egypt, and other parts of Africa, it is widely used in the traditional Indian medicinal system to treat various health conditions. The plant has been used in jaundice, diabetes, hemorrhoids, dysentery, headache, ringworm infection, and leprosy. More than 50 chemical compounds have been isolated from a plant which mainly comprises flavonoids, anthraquinones, proteins, fatty acids, saponin triterpene, volatile components, and other phytoconstituents. Read More

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October 2018
5 Reads

Validity and Reliability of the measure yourself medical outcome profile 2 (MYMOP2) questionnaire among Turkish patients having anorectal disorders.

Turk J Gastroenterol 2018 Nov 16. Epub 2018 Nov 16.

Department of Physiotherapy and Rehabilitation, Bahçesehir University School of Health Sciences, İstanbul, Turkey.

Background/aims: Measure Yourself Medical Outcome Profile 2 (MYMOP2) is a patient-generated outcome measure allowing patients to select the problems that are the most important to them and that they want to address, and it measures the effects of the problem from a wide range of health care interventions. This study aimed to translate the questionnaire into Turkish language (Turkish MYMOP-TMYMOP) and add this clinically useful measure to Turkish medical practice by assessing its validity and reliability.

Materials And Methods: Fifty volunteers with anorectal disorders were prospectively included into the study. Read More

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November 2018

Hemorrhoidal Disease Symptom Score and Short Health ScaleHD: New Tools to Evaluate Symptoms and Health-Related Quality of Life in Hemorrhoidal Disease.

Dis Colon Rectum 2018 Nov 15. Epub 2018 Nov 15.

Background: There are no adequately validated tools to evaluate symptoms or disease-specific health-related quality of life in hemorrhoidal disease.

Objective: The purpose of this study was to assess validity, reliability, and responsiveness of a symptom score of patient-reported pain, itching, bleeding, soiling, and prolapse (Hemorrhoidal Disease Symptom Score). In addition, the study set out to assess reliability and responsiveness of an instrument to measure health-related quality of life in patients with hemorrhoids (Short Health ScaleHD), with 1 item in its 4 dimensions: symptom load, functional status, disease-specific worries, and general well-being. Read More

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November 2018
5 Reads

Transanal hemorrhoidal dearterialization (THD) versus stapled hemorrhoidopexy (SH) in treatment of internal hemorrhoids: a systematic review and meta-analysis of randomized clinical trials.

Int J Colorectal Dis 2018 Nov 12. Epub 2018 Nov 12.

Department of General surgery, colorectal surgery unit, Mansoura Faculty of medicine, Mansoura University Hospitals, Elgomhuoria Street, Mansoura, Egypt.

Background: Although conventional hemorrhoidectomy proved effective in treatment of hemorrhoidal disease, postoperative pain remains a vexing problem. Alternatives to conventional hemorrhoidectomy as transanal hemorrhoidal dearterialization (THD) and stapled hemorrhoidopexy (SH) were described. The present meta-analysis aimed to review the randomized trials that compared THD and SH to determine which technique is superior in terms of recurrence of hemorrhoids, complications, and postoperative pain. Read More

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November 2018
7 Reads

Haemorrhoids - A neglected problem faced by women after birth.

Sex Reprod Healthc 2018 Dec 18;18:30-36. Epub 2018 Aug 18.

Department of Women's and Children's Health, Karolinska Institute, Sweden.

Objective: To investigate the prevalence and severity of haemorrhoids after birth among first-time mothers in relation to management during the second stage of labour and to describe the women's experiences with haemorrhoids.

Method: A mixed method explanatory sequential design was used. Nulliparous women were allocated to an intervention group for whom the second-stage of labour practice followed the MIMA model (Midwives management during second stage of labour) or to a control group for whom standard-care practice was followed. Read More

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December 2018
3 Reads

Laparoscopic rectal tumor surgery after administration of a new sclerosing therapy (aluminum potassium sulfate and tannic acid injection) for internal hemorrhoids: A report of three cases.

Asian J Endosc Surg 2018 Nov 8. Epub 2018 Nov 8.

Department of Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.

Aluminum potassium sulfate and tannic acid (ALTA) injection is a new sclerosing therapy for internal hemorrhoids that has been gaining widespread use. However, there have been few reports about rectal cancer after ALTA injection. We performed laparoscopic surgery for three patients who had underwent ALTA therapy 6 months or 1 year earlier: (i) a 51-year-old man with neuroendocrine tumor; (ii) a 44-year-old woman with rectal cancer; and (iii) 77-year-old man with rectal cancer. Read More

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November 2018
5 Reads

Colonoscopy as Part of Pre-Transplant Work-Up in Successful Kidney Transplant Candidates: Single-Center Experience and Review of Literature.

Ann Transplant 2018 Nov 9;23:782-788. Epub 2018 Nov 9.

Department of Nephrology, Transplantology, and Internal Medicine, Medical University of Gdańsk, Gdańsk, Poland.

BACKGROUND Screening colonoscopy is not obligatory in kidney pre-transplant work-up guidelines. According to recommendations, only transplant recipients over age 50 years should be screened. The aim of this study was to characterize endoscopic findings revealed as part of pre-transplant work-up. Read More

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November 2018
1 Read

Correction to: Conservative Treatment of Hemorrhoids: Results of an Observational Multicenter Study.

Adv Ther 2018 Nov;35(11):1993

Clinic 'MEDSI MSK 12', Moscow, Russia.

The article "Conservative Treatment of Hemorrhoids: Results of an Observational Multicenter Study", written by Evgeny A. Zagriadskiĭ, Alexey M. Bogomazov, Evgeny B. Read More

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November 2018

Factors Influencing Patient Delay in Individuals with Haemorrhoids: A Study Based on Theory of Planned Behavior and Common Sense Model.

J Adv Nurs 2018 Oct 30. Epub 2018 Oct 30.

School of Nursing, Jilin University, Changchun, People's Republic of China.

Aims: This study aimed to describe the status of patient delay and examine related factors affecting patient delay in individuals with haemorrhoids in mainland China, based on theory of planned behavior and common sense model.

Background: Studies on patient delay have mainly focused on cancer, tuberculosis and myocardial infarction, but studies on patient delay in individuals with haemorrhoids have yet to be conducted. Compared with other diseases, haemorrhoids are initially considered benign. Read More

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October 2018
8 Reads
1.685 Impact Factor

Role of interleukin-17 in the pathogenesis of perianal abscess and anal fistula: a clinical study on 50 patients with perianal abscess.

ANZ J Surg 2018 Oct 25. Epub 2018 Oct 25.

Department of Colorectal and Anal Surgery, Jinhua Municipal Central Hospital, Jinhua, China.

Background: To investigate the role of interleukin (IL)-17 in tissue and peripheral blood of perianal abscess and anal fistula.

Methods: Patients with primary perianal abscess (n = 50) admitted to Jinhua Municipal Central Hospital between March 2003 and August 2004 were enrolled. Fifty patients with mixed haemorrhoids, who showed no perianal abscess or anal fistula, were also recruited as the control. Read More

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October 2018
2 Reads

Can colonoscopy at peripheral day hospitals meet internationally accepted quality and safety standards?

N Z Med J 2018 Oct 26;131(1484):26-29. Epub 2018 Oct 26.

Gastroenterology, Christchurch Hospital, Christchurch.

Aims: To perform an independent review of the quality and safety of colonoscopy service at the Canterbury Charity Hospital (CCH).

Methods: Demographic, endoscopy and histology data on all colonoscopies performed at CCH between 1 October 2016 and 31 September 2017 were collected. Quality indicators ascertained were caecal intubation rate, mean withdrawal time and adenoma detection rate (ADR). Read More

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October 2018
6 Reads

Risk of delayed bleeding after hemorrhoidectomy.

Int J Colorectal Dis 2018 Oct 24. Epub 2018 Oct 24.

Division of Colorectal Surgery, Department of Surgery, Chang Gung Memorial Hospital - Kaohsiung Medical Center, Chang Gung University College of Medicine, No. 123, DAPI Rd. Niaosng Dist, Kaohsiung City, 83301, Taiwan.

Purpose: Delayed post-hemorrhoidectomy bleeding (DPHB) is a rare but serious complication. We investigated the incidence and risk factors of DPHB in patients undergoing hemorrhoidectomy using the LigaSure device or the Ferguson procedure.

Methods: This retrospective study included 382 consecutive patients with symptomatic grades II to IV hemorrhoids who received either LigaSure (184 patients) or Ferguson (198 patients) hemorrhoidectomy procedures. Read More

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October 2018
12 Reads

15 years experience in proctological day-surgery.

Ann Ital Chir 2018 ;89:324-329

Introduction: The actual high hospitalization costs have encouraged a growing attention towards reducing hospital stay. Nowadays, many simple surgical procedures are carried out in a one-day surgery regimen . A shorter hospital stay brings many advantages for the patients: lesser inconvenience, a lower risk of hospital infection and an earlier return to work. Read More

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January 2018
4 Reads

: Botany, Medicinal Uses, Phytochemistry, and Pharmacological Properties.

Authors:
Alfred Maroyi

ScientificWorldJournal 2018 20;2018:7463584. Epub 2018 Sep 20.

Medicinal Plants and Economic Development (MPED) Research Centre, Department of Botany, University of Fort Hare, Private Bag X1314, Alice 5700, South Africa.

The bark, leaves, and roots of are highly sought after in tropical Africa as herbal medicines. Therefore, the aim of this study was to review the botany, medicinal uses, phytochemistry, and pharmacological properties of so as to provide baseline data required for evaluating the therapeutic potential of the species. Information on the botanical profile, medicinal uses, phytochemistry, and pharmacological properties of was undertaken using databases such as ScienceDirect, SciFinder, Pubmed, Google Scholar, Medline, SCOPUS, EThOS, ProQuest, OATD, and Open-thesis. Read More

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September 2018
10 Reads

In Vivo Evaluation of ' Wound-Healing Activity.

Sci Pharm 2018 Oct 7;86(4). Epub 2018 Oct 7.

Department of Clinical Pharmacy and Therapeutics, Applied Science Private University, 11931 Amman, Jordan.

Mediterranean-native perennial plant was scrutinized in this study for its antioxidant activity and its total phenolic content in order to test for the plant's wound-healing capability. The traditional uses of this plant to treat gum scurvy, various tumors, ulcers, and hemorrhoids were the main idea behind this study. Leaves and flowers of the were extracted by maceration. Read More

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October 2018
1 Read

Long-term results after stapled hemorrhoidopexy: a survey study with mean follow-up of 12 years.

Tech Coloproctol 2018 09 4;22(9):689-696. Epub 2018 Oct 4.

Proctological and Perineal Surgical Unit, Cisanello University Hospital, Via Paradisa 2, Pisa, Italy.

Background: Hemorrhoidal prolapse is a common benign disease. The introduction of circular-stapled hemorrhoidopexy as an alternative to the conventional hemorrhoidectomy led to a new spectrum of postoperative outcomes and complications. The aim of the present study was to evaluate long-term results after stapled hemorrhoidopexy. Read More

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September 2018
4 Reads

Conservative Treatment of Hemorrhoids: Results of an Observational Multicenter Study.

Adv Ther 2018 Nov 1;35(11):1979-1992. Epub 2018 Oct 1.

Clinic 'MEDSI MSK 12', Moscow, Russia.

Introduction: This study was conducted to determine the frequency of complaints in a cohort of patients with symptomatic hemorrhoidal disease (HD) treated with micronized purified flavonoid fraction (MPFF, Detralex). MPFF was selected for conservative treatment in this population owing to its proven effects on hemorrhoidal symptoms in a large number of patients.

Methods: This multicenter, non-interventional study was part of the international CHORUS survey (Chronic venous and HemORrhoidal diseases evalUation for improvement of Scientific knowledge), conducted in nine centers in different regions of Russia with the participation of 80 coloproctologists. Read More

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November 2018
11 Reads

An interesting case of anal melanoma caused liver metastases due to misdiagnosed as hemorrhoids.

Authors:
Tarık Akar

Turk J Gastroenterol 2018 09;29(5):619-620

Department of Gastroenterology, Bülent Ecevit University, Zonguldak, Turkey.

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September 2018
1 Read

Day case versus inpatient stay for excisional haemorrhoidectomy.

ANZ J Surg 2018 Sep 21. Epub 2018 Sep 21.

Department of Surgery, South Auckland Clinical Campus, Middlemore Hospital, The University of Auckland, Auckland, New Zealand.

Background: Excisional haemorrhoidectomy has traditionally been performed on an inpatient basis due to concerns over post-operative pain and urinary retention. Day case procedures are increasingly common. This study aims to investigate readmission rates following day case compared with inpatient haemorrhoidectomy. Read More

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September 2018
1 Read

Effectiveness of Lifestyle Modification Education on Knowledge, Anxiety, and Postoperative Problems of Patients With Benign Perianal Diseases.

J Perianesth Nurs 2018 Oct 28;33(5):640-650. Epub 2017 Sep 28.

Purpose: The aim of this study was to evaluate the effectiveness of preoperative planned education about lifestyle modifications on knowledge, anxiety level, and postoperative problems of the patients with benign perianal disease.

Design: The study was a quasi-experimental design.

Methods: The sample was a total of 102 patients undergoing surgical procedure for hemorrhoid and fissure in the general surgery unit of a state hospital in Turkey. Read More

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October 2018
1 Read

Dilating Vascular Diseases: Pathophysiology and Clinical Aspects.

Int J Vasc Med 2018 26;2018:9024278. Epub 2018 Aug 26.

Ankara Education and Research Hospital, Department of Cardiology, Ankara, Turkey.

Atherosclerotic disease of the vessels is a significant problem affecting mortality and morbidity all over the world. However, dilatation of the vessels either in the arterial system or in the venous territory is another vessel disease. Varicocele, pelvic, and peripheral varicose veins and hemorrhoids are aneurysms of the venous vascular regions and have been defined as dilating venous disease, recently. Read More

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August 2018
1 Read

MMP-1/TIMP-1 expressions in rectal submucosa of females with obstructed defecation syndrome associated with internal rectal prolapse.

Histol Histopathol 2018 Sep 17:18041. Epub 2018 Sep 17.

Department of Anal-colorectal Surgery, Jingzhou Central Hospital, the Second Clinical Medical College, Yangtze University, Jingzhou, China.

Objective: To explore the MMP-1/TIMP-1 expressions in rectal submucosa of females with obstructed defecation syndrome (ODS) associated with internal rectal prolapse (IRP).

Methods: Fifty-six female patients with ODS associated with IRP were enrolled as Case group, and 43 female hemorrhoids of stages III-IV without constipation and IRP were enrolled as Control group. Quantitative reverse transcription polymerase chain reaction (qRT-PCR) and immunohistochemistry were performed to test the expressions of MMP-1/TIMP-1 in the rectal submucosa. Read More

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September 2018
6 Reads

Offering HeLP to work out the optimum treatment for haemorrhoidal disease.

Tech Coloproctol 2018 08 14;22(8):567-568. Epub 2018 Sep 14.

Department of General Surgery, Sheffield Teaching Hospitals, Sheffield, S5 7AU, UK.

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August 2018
1 Read

[Common sense of diosmin administration in combined treatment of hemorrhoids].

Khirurgiia (Mosk) 2018 (8. Vyp. 2):83-89

Sechenov First Moscow State Medical University of Healthcare Ministry of Russia, Moscow, Russia, GMS Clinic and Hospitals, Moscow, Russia, Colorectal Surgery Department of the Cleveland Clinic Florida, Weston, USA.

Flavonoids are herbal medicines and widely used for chronic venous diseases and hemorrhoids. Flavonoid diosmin in both micronized and non-micronized form is a part of various drugs. According to literature data, flavonoids are able to reduce venous stasis, suppress local inflammation, improve venous tone and lymphatic outflow. Read More

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January 2018
1 Read

The Effect of Nonoperative Management of Chronic Anal Fissure and Hemorrhoid Disease on Bowel Function Patient-Reported Outcomes.

Dis Colon Rectum 2018 Oct;61(10):1223-1227

Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire.

Background: Nonoperative management has been reported to decrease symptoms from common anorectal conditions such as chronic anal fissures and hemorrhoids. The effects of these interventions on bowel function are unknown.

Objective: This study aims to perform a prospective evaluation of patient-reported outcomes of bowel function on nonoperative management for chronic anal fissures and hemorrhoid disease. Read More

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October 2018
12 Reads

High post-operative pain scores despite multimodal analgesia in ambulatory anorectal surgery: a prospective cohort study.

Acta Chir Belg 2018 Sep 7:1-7. Epub 2018 Sep 7.

a Department of Ambulatory Surgery , Ghent University , Ghent , Belgium.

Background: Ambulatory surgery for anorectal procedures has become widely accepted. Recent reviews recommend a multimodal approach to pain management. However, these recommendations are largely based on single intervention studies. Read More

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September 2018
2 Reads

Endoscopic treatment of internal hemorrhoids by use of a bipolar system.

VideoGIE 2017 Oct 12;2(10):290-292. Epub 2017 Aug 12.

Department of Gastroenterology and Hepatology, Division of Interventional Endoscopy, Geisinger Medical Center, Danville, Pennsylvania, USA.

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October 2017
1 Read

Psychometric properties of a questionnaire (HEMO-FISS-QoL) to evaluate the burden associated with haemorrhoidal disease and anal fissures.

Colorectal Dis 2018 Sep 1. Epub 2018 Sep 1.

Pierre Fabre SA, Boulogne-Billancourt, France.

Aim: Current questionnaires designed to evaluate the burden of haemorrhoidal disease ignore symptoms such as bleeding, pain and itching. A specific questionnaire is needed to evaluate the global impact of anal disorders on patients' daily lives.

Method: We developed a questionnaire (HEMO-FISS-QoL) to assess the symptom burden of anal disorders and administered it to 256 patients (mean age 46. Read More

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September 2018
1 Read

Doppler-guided hemorrhoidal dearterialization with laser (HeLP): a prospective analysis of data from a multicenter trial.

Tech Coloproctol 2018 08 29;22(8):635-643. Epub 2018 Aug 29.

Department. of Gastrointestinal Surgery, Scientific Institute San Raffaele, Milan, Italy.

Background: Doppler-guided hemorrhoidal laser procedure (HeLP) is a new minimally invasive technique to treat symptomatic hemorrhoids. The aim of this multicenter study was to prospectively assess clinical results and patients' satisfaction in patients treated with HeLP.

Methods: Indications for HeLP included patients with symptomatic hemorrhoids resistant to medical therapy, with low-grade prolapse. Read More

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August 2018
14 Reads

Comparative Bioavailability of Two Diosmin Formulations after Oral Administration to Healthy Volunteers.

Molecules 2018 Aug 29;23(9). Epub 2018 Aug 29.

Dipartimento di Farmacia, Università di Salerno, via Giovanni Paolo II 132, 84084 Fisciano (SA), Italy.

Diosmin is a flavonoid commonly found in citrus fruits, largely used as adjuvant treatment for circulatory disorders, including chronic venous insufficiency (CVI) and hemorrhoids. Following oral administration, diosmin is not directly absorbed but must first be hydrolyzed into its aglycone, diosmetin, which is then absorbed into the systemic circulation. The aim of the current cross-over clinical study was to assess the pharmacokinetic profile of µSmin Plus, a micronized diosmin flavonoid complex standardized in diosmin and formulated with a buffering agent (tested formulation). Read More

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August 2018
17 Reads

Management of rectal bleeding due to internal haemorrhoids with arterial embolisation: a single-centre experience and protocol.

Clin Radiol 2018 Nov 24;73(11):985.e1-985.e6. Epub 2018 Aug 24.

Oncology Department, The Affiliated Suzhou Hospital of Nanjing Medical University, Guangji Road 242, Suzhou 215008, Jiangsu, China. Electronic address:

Aim: To evaluate the safety and efficacy of arterial embolisation for rectal bleeding due to internal haemorrhoids.

Materials And Methods: Twenty-three patients received arterial embolisation for rectal bleeding due to internal haemorrhoids. Clinical records, technical success, and complications were analysed retrospectively. Read More

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November 2018
3 Reads

Early and late puerperal complications associated with the mode of delivery in a cohort in Brazil.

Rev Bras Epidemiol 2018 Aug 20;21:e180010. Epub 2018 Aug 20.

Centro de Pesquisas Epidemiológicas, Programa de Pós-Graduação em Epidemiologia, Universidade Federal de Pelotas - Pelotas (RS), Brasil.

Introduction: The rates of cesarean section births significantly increased in Brazil and worldwide in recent years; and along with them, the interest in studying the complications related to this procedure.

Objective: To assess the early and late maternal complications associated with the mode of delivery in up to six years after labor.

Methods: This is a prospective cohort study that followed all births in the city of Pelotas, in Southern Brazil (4,244 mothers) in 2004, for a period of 6 years. Read More

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August 2018
8 Reads

Effect of acupuncture on post-hemorrhoidectomy pain: a randomized controlled trial.

J Pain Res 2018 6;11:1489-1496. Epub 2018 Aug 6.

The Acupuncture Department, Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, People's Republic of China,

Objectives: To observe the clinical efficacy and safety of electroacupuncture (EA) in relieving pain after hemorrhoidectomy treatment for mixed hemorrhoids.

Design: This was a randomized controlled trial.

Methods: We conducted a single-center, single-blind, and randomized controlled clinical trial. Read More

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August 2018
14 Reads

The clinical anatomy of dyspareunia: A review.

Clin Anat 2018 Oct 26;31(7):1013-1017. Epub 2018 Oct 26.

Seattle Science Foundation, Seattle, Washington.

Dyspareunia can be described as continuous unremitting or intermittent pain associated with intercourse. It can be classified based on the location of the pain - entry or deep dyspareunia, or based on when the pain was first experienced - primary or secondary dyspareunia. There are different causes of dyspareunia and some of the most important causes include the following: vulvodynia, postpartum dyspareunia, endometriosis, inadequate vaginal lubrication or arousal, and other anogenital causes such as hemorrhoids and anal fissures. Read More

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October 2018
9 Reads

Two-year retrospective analysis of patients undergoing direct to procedure flexible sigmoidoscopy investigation with rectal bleeding as a primary complaint.

Endosc Int Open 2018 Aug 10;6(8):E1059-E1064. Epub 2018 Aug 10.

Gastrointestinal Diseases Research Unit (GIDRU), Department of Medicine, Queen's University, Kingston ON, Canada.

Background And Aims:  Rectal bleeding affects ~15 % of the general population and is a common reason for referral to gastroenterologists by primary care physicians. Direct to procedure flexible sigmoidoscopy is an appealing modality to investigate rectal bleeding due its diagnostic yield, safety profile, and accessibility. Patients referred on a routine basis for direct to procedure clinic by primary care physicians with the sole complaint of rectal bleeding have not previously been studied. Read More

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August 2018
1 Read

Benign Anorectal Surgery: Management.

Authors:
Jan Rakinic

Adv Surg 2018 Sep 19;52(1):179-204. Epub 2018 Jun 19.

Department of Surgery, Southern Illinois University School of Medicine, 701 North First Street, Suite D-333, Springfield, IL 62781-0001, USA. Electronic address:

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September 2018
5 Reads

Metabolite profiling of "green" extracts of Corylus avellana leaves by H NMR spectroscopy and multivariate statistical analysis.

J Pharm Biomed Anal 2018 Oct 26;160:168-178. Epub 2018 Jul 26.

Dipartimento di Farmacia, Università degli Studi di Salerno, via Giovanni Paolo II n. 132, 84084 Fisciano, SA, Italy. Electronic address:

Corylus avellana L. (Betulaceae) leaves, consumed as infusion, are used in traditional medicine, for the treatment of hemorrhoids, varicose veins, phlebitis, and edema due to their astringent, vasoprotective, and antiedema properties. In previous works we reported from the leaves of Corylus avellana cv. Read More

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October 2018
6 Reads

Effect of lateral internal sphincterotomy in patients undergoing excisional hemorrhoidectomy.

Medicine (Baltimore) 2018 Aug;97(32):e11820

Department of Integrated Traditional Chinese and Western Medicine, West China Hospital, Sichuan University.

Background: Excisional hemorrhoidectomy (EH) is the major surgical option for high-grade symptomatic hemorrhoids, but it has some shortcomings, especially postoperative pain. This study was performed to assess the effect of lateral internal sphincterotomy (LIS) in patients undergoing excisional hemorrhoidectomy.

Methods: A systematic literature search (Medline, Embase, Cochrane Library, Science Citation Index, Science Direct, Springer Link, Ovid Journals, and EBSCO) was performed to identify all eligible articles. Read More

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August 2018
1 Read

Conservative management of pelvic sepsis with severe shock and multiple organ dysfunction syndrome after rubber-band ligation of internal haemorrhoids: surgery is not the only option.

J Surg Case Rep 2018 Aug 7;2018(8):rjy199. Epub 2018 Aug 7.

Centre Hospitalier de l'Université de Montréal (CHUM), Service de Chirurgie Digestive, 1051 rue Sanguinet, Montréal, Québec, Canada.

Rubber-band ligation (RBL) is a safe and cost-effective approach to internal haemorrhoids. Potential side effects include pain, bleeding, urinary retention and occasionally pelvic sepsis and systemic inflammatory response syndrome (SIRS). At-risk patients are mainly those with immunocompromising conditions. Read More

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August 2018
9 Reads

[Proctological emergencies in pregnant women].

Rev Med Suisse 2018 Aug;14(614):1394-1396

Département des urgences, HNE, site de Pourtalès, 45 rue de la Maladière, 2000 Neuchâtel.

Hemorrhoids affect up to 85 % of pregnant women during the last two trimesters. The maximum incidence for anal fissure is 20 %. One of the common risk factors is constipation promoted during pregnancy. Read More

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August 2018
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