6,304 results match your criteria Hemorrhoids


Beware of anal fissures: pemphigus vulgaris of the anal canal.

Ann Gastroenterol 2019 Mar-Apr;32(2):205-207. Epub 2018 Dec 20.

Depatment of Dermatology, University General Hospital of Heraklion, Crete (Chara Karatzi, Maria Stefanidou, Eva Islamidou, George Evangelou, Sabine Krueger-Krasagakis, Konstantin Krasagakis), Greece.

A case of anal pemphigus vulgaris in a 49-year-old female suffering from pemphigus vulgaris of the oral cavity is reported. The oral manifestations were in remission until she presented with episodes of anal pain and bleeding on defecation, initially mimicking anal fissures. Inspection revealed prominent painful erosions in the anal canal with external hemorrhoids and strands of sloughing skin and maceration in the anal verge. Read More

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http://dx.doi.org/10.20524/aog.2018.0340DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394260PMC
December 2018
1 Read

Prevalence and genotypes of anal human papillomavirus infection among HIV-positive vs. HIV-negative men in Taizhou, China.

Epidemiol Infect 2019 Jan;147:e117

Department of Epidemiology,School of Public Health, and the Key Laboratory of Public Health Safety of Ministry of Education, Fudan University,Shanghai,China.

This study aims to investigate the prevalence and genotype distribution of anal human papillomavirus (HPV) infection among men with different sexual orientations with or without human immunodeficiency virus (HIV) in China. A cross-sectional study was conducted during 2016-2017 in Taizhou City, Zhejiang Province. Convenient sampling was used to recruit male participants from HIV voluntary counselling and testing clinics and Center for Disease Control and Prevention. Read More

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http://dx.doi.org/10.1017/S0950268818003205DOI Listing
January 2019

Haemorrhoidal Artery Ligation Operation Without Doppler Guidance.

J Ayub Med Coll Abbottabad 2018 Oct-Dec;30(Suppl 1)(4):S664-S667

Department of Surgery, Combined Military Hospital, Rawalpindi, Pakistan.

Background: A range of surgical options from banding to open haemorrhoidectomy are available for the treatment of haemorrhoids. Haemorrhoidal artery ligation operation (HALO) with or without Doppler guidance is a newer option with claims of having better efficacy. We aimed to study the efficacy of HALO without Doppler guidance in terms of presence of postoperative complications including pain, bleeding, prolapse and overall patient satisfaction. Read More

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Two-year delay in ulcerative colitis diagnosis is associated with anti-tumor necrosis factor alpha use.

World J Gastroenterol 2019 Feb;25(8):989-1001

Division of Gastroenterology, Department of Internal Medicine, Dongtan Sacred Heart Hospital, Hallym University College of Medicine, Hwaseong 18450, South Korea.

Background: Ulcerative colitis (UC) is an uncommon inflammatory bowel disease (IBD). However, its incidence has recently increased in South Korea. Moreover, UC diagnoses are frequently delayed, and the relationship between diagnostic delay and UC prognosis has not been extensively studied in South Korean patients. Read More

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http://dx.doi.org/10.3748/wjg.v25.i8.989DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397722PMC
February 2019
1 Read

Effect of Genetic Factors on the Etiopathogenesis of Thrombosed Hemorrhoidal Disease.

Chirurgia (Bucur) 2019 Jan-Feb;114(1):89-94

Objective: The aim of this study is to investigate whether genetic factors known to increase thrombosis risk play a role in the etiopathogenesis of thrombosed hemorrhoidal disease. Genomic DNA from patients with thrombosed hemorrhoidal disease was analyzed for the presence of factor V Leiden, prothrombin G20210A, methylenetetrahydrofolate reductase C677T, and methylenetetrahydrofolate reductase A1298C mutations. No significant differences were found in the allele frequencies of factor V Leiden, prothrombin G20210A, methylenetetrahydrofolate reductase C677T, and methylenetetrahydrofolate reductase A1298C mutations between patients with thrombosed hemorrhoidal disease and controls (p 0. Read More

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http://www.revistachirurgia.ro/pdfs/2019-1-89.pdf
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http://dx.doi.org/10.21614/chirurgia.114.1.89DOI Listing
February 2019
5 Reads

[Potential Use of Sacran for Dermal and Oral Preparations].

Yakugaku Zasshi 2019 ;139(3):385-391

Department of Physical Pharmaceutics, Graduate School of Pharmaceutical Sciences, Kumamoto University.

Sacran, a new polysaccharide isolated from cyanobacterium Aphanothece sacrum (Sur.) Okada, is known to have potential as an active pharmaceutical ingredient (API) for the treatment of atopic dermatitis, various types of dermatitis, skin wound, hemorrhoids and corneal epithelium disorder. In the present studies, the effects of sacran on skin injury and skin pain induced by stratum corneum tape-stripping and gastric ulcer induced by indomethacin, a non-steroidal anti-inflammatory drug (NSAID), and hydrochloride/ethanol (HCl/EtOH) in mice were investigated. Read More

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http://dx.doi.org/10.1248/yakushi.18-00177-5DOI Listing
January 2019

Hemorrhoids, Tremor, C. difficile Infection, Migraine, Vitamin D Screening.

Authors:

Am Fam Physician 2019 Mar;99(5):285

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March 2019
1 Read

Association between education and health outcomes among adults with disabilities: evidence from Shanghai, China.

PeerJ 2019 19;7:e6382. Epub 2019 Feb 19.

Department of Health Policy and Management/ School of Public Health, Fudan University, Shanghai, China.

Background: Adults with disabilities often have worse health outcomes than do their peers without disabilities. While education is a key determinant of health, there is little research available on the health disparities across education levels among adults with disabilities in developing countries. We therefore examined the association between health outcomes and education among adults with disabilities in Shanghai, China. Read More

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http://dx.doi.org/10.7717/peerj.6382DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385680PMC
February 2019
1 Read

Short-Term Outcomes of Transanal Hemorrhoidal Dearterialization With Mucopexy Versus Vessel-Sealing Device Hemorrhoidectomy for Grade III to IV Hemorrhoids: A Prospective Randomized Multicenter Trial: THDLIGA-RCT.

Dis Colon Rectum 2019 Feb 19. Epub 2019 Feb 19.

Background: Transanal hemorrhoidal dearterialization with mucopexy and vessel-sealing device hemorrhoidectomy seems to reduce postoperative pain compared with classic excisional hemorrhoidectomy, but whether one of them is superior remains unclear.

Objective: We compared transanal hemorrhoidal dearterialization with mucopexy and vessel-sealing device hemorrhoidectomy.

Design: This was a multicenter, randomized controlled trial. Read More

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http://dx.doi.org/10.1097/DCR.0000000000001362DOI Listing
February 2019
3 Reads

Perioperative Adverse Events in Women Undergoing Concurrent Hemorrhoidectomy at the Time of Urogynecologic Surgery.

Female Pelvic Med Reconstr Surg 2019 Mar/Apr;25(2):88-92

From the Center for Urogynecology and Reconstructive Pelvic Surgery, Department of Obstetrics, Gynecology & Women's Health Institute, Cleveland Clinic, Cleveland, OH.

Objective: The aim of this study was to describe the incidence and trends of outcomes after concurrent surgeries for symptomatic hemorrhoids and pelvic floor disorders.

Methods: This was a retrospective matched cohort study. Women who underwent concurrent vaginal urogynecologic and hemorrhoid surgery between 2007 and 2017 were identified by their surgical codes and matched to a cohort of women who underwent vaginal urogynecologic surgery only. Read More

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http://dx.doi.org/10.1097/SPV.0000000000000663DOI Listing
February 2019
2 Reads

Effect of Topical Baclofen 5% on Post-Hemorrhoidectomy Pain: Randomized Double Blind Placebo-Controlled Clinical Trial.

J Gastrointest Surg 2019 Feb 19. Epub 2019 Feb 19.

Department of Clinical Pharmacy, Nephrology and Kidney Transplant Research Center, Faculty of Pharmacy, Urmia University of Medical Sciences, Urmia, Iran.

Background: Baclofen is an agonist for a subtype of gamma-amino butyric acid (GABA-B) receptors and traditionally been used for the systemic treatment of spasticity. Topical application of baclofen has been shown to reduce pain in patients with localized neuropathic pain.

Objectives: In this study, we investigate the efficacy of baclofen cream (5%) in reducing postoperative pain and analgesic requirement after open hemorrhoidectomy. Read More

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http://dx.doi.org/10.1007/s11605-019-04147-7DOI Listing
February 2019
7 Reads
2.798 Impact Factor

Burden and Cost of Outpatient Hemorrhoids in the United States Employer-Insured Population, 2014.

Am J Gastroenterol 2019 Feb 7. Epub 2019 Feb 7.

Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina.

Introduction: Although hemorrhoids are a common indication for seeking health care, there are no contemporary estimates of burden and cost. We examined data from an administrative claims database to estimate health care use and aggregate costs.

Methods: We conducted a cross-sectional study using the MarketScan Commercial Claims and Encounters Database for 2014. Read More

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http://dx.doi.org/10.14309/ajg.0000000000000143DOI Listing
February 2019
1 Read

Somatosensory stimulation treatments for postoperative analgesia of mixed hemorrhoids: Protocol for a systematic review and network meta-analysis.

Medicine (Baltimore) 2019 Feb;98(6):e14441

The 3rd Teaching Hospital/Acupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine.

Background: Pain after hemorrhoidal surgery bothers both clinicians and patients. Somatosensory stimulation treatments have shown promising effect on the pain after hemorrhoidal surgery, but the comparative effectiveness between them has not been studied. We aim to determine the relative effectiveness among these treatments on pain relief after hemorrhoidal surgery by using network meta-analysis. Read More

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http://dx.doi.org/10.1097/MD.0000000000014441DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380832PMC
February 2019
2 Reads
5.723 Impact Factor

Hemorrhoidal disease: Predilection sites, pattern of presentation, and treatment.

Ann Afr Med 2019 Jan-Mar;18(1):12-16

Oak Endoscopy Centre, Digestive Disease Unit, Port Harcourt, Nigeria.

Background: An engorgement and prolapse of the anal cushion lead to haemorrhoidal disease. There are different anatomical sites and presentation of this common pathology which affects the quality of life.

Aims: To study the predilection sites, presentation and treatment of haemorrhoidal disease. Read More

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http://www.annalsafrmed.org/text.asp?2019/18/1/12/251584
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http://dx.doi.org/10.4103/aam.aam_4_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380113PMC
February 2019
4 Reads

A validated severity score for haemorrhoids as an essential prerequisite for future haemorrhoid trials.

Tech Coloproctol 2019 Jan 6;23(1):33-41. Epub 2019 Feb 6.

Department of Surgery, Sheffield Teaching Hospitals, Northern General Hospital, Sheffield, UK.

Background: There is a lack of standardised outcomes for haemorrhoidal disease making comparison between trials difficult. A need for a very well validated severity score is essential to facilitate meta-analysis of comparative studies, enabling evidence-based clinical practice.

Methods: The Hubble trial provides a large cohort of patients with haemorrhoidal disease randomised to rubber band ligation (RBL) or haemorrhoidal artery ligation. Read More

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http://dx.doi.org/10.1007/s10151-019-01936-9DOI Listing
January 2019
2 Reads

Fecal evacuation disorders in anal fissure, hemorrhoids, and solitary rectal ulcer syndrome.

Indian J Gastroenterol 2019 Feb 1. Epub 2019 Feb 1.

Department of Gastroenterology, Gleneagles Global Health City, 439, Cheran Nagar, Chennai, 600 100, India.

The causative factors for hemorrhoids, anal fissure, and solitary rectal ulcer syndrome (SRUS) are poorly understood. The study was done to identify the prevalence of fecal evacuation disorders in patients with anal fissure, hemorrhoids, and SRUS using anorectal manometry (ARM). Retrospective analysis of ARM data from three centers across India was done. Read More

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http://dx.doi.org/10.1007/s12664-018-0927-9DOI Listing
February 2019
2 Reads

Short- and long-term outcomes of laser haemorrhoidoplasty for grade II-III haemorrhoidal disease.

Colorectal Dis 2019 Jan 31. Epub 2019 Jan 31.

Department of Surgery, Cantonal Hospital Baden, Baden, Switzerland.

Aim: Laser haemorrhoidoplasty is associated with minimal postoperative pain and good symptom improvement in the short-term. However, less is known about its long-term efficacy. This study aims to determine the short- and long-term outcomes of laser haemorrhoidoplasty. Read More

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http://dx.doi.org/10.1111/codi.14572DOI Listing
January 2019
3 Reads

ELITE: a diode laser minimal invasive technique for hemorrhoids during the surgical treatment for anal fissure.

J Surg Case Rep 2019 Jan 24;2019(1):rjy363. Epub 2019 Jan 24.

University of Nicosia Medical School, Nicosia, Cyprus.

A 44-year-old male patient diagnosed with Anal Fissure and Stage II Hemorrhoids in 2013. He has been suffering ever since, avoiding surgery, using local analgesic and anti-hemorrhoidal crèmes. Physical examination in February 2017, showed a chronic character of his problem and hemorrhoids to have progressed to Stage III. Read More

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http://dx.doi.org/10.1093/jscr/rjy363DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344920PMC
January 2019
2 Reads

High-performance countercurrent chromatographic isolation of acylated iridoid diglycosides from Verbascum ovalifolium Donn ex Sims and evaluation of their inhibitory potential on IL-8 and TNF-α production.

J Pharm Biomed Anal 2019 Mar 18;166:295-303. Epub 2019 Jan 18.

Department of Pharmacognosy with Medicinal Plant Unit, Medical University of Lublin, Chodzki 1, 20-093 Lublin, Poland.

In traditional folk medicine, Verbascum species have been used since ancient times to treat respiratory disorders, hemorrhoids, diarrhea, wounds, eczema and other types of inflammatory skin conditions. Despite the fact that more than 200 bioactive constituents (phenylethanoids, flavonoids, neolignan glycosides, phenolic acids, iridoids, saponins and polysaccharides) have been previously isolated from various Verbascum species, to date preparative high-performance countercurrent chromatography (HPCCC) has never been employed for this purpose. Therefore, in this study, simple HPCCC methods were successfully developed with the aim to primarily isolate acylated iridoid diglycosides from Verbascum ovalifolium Donn ex Sims (oval-leaved mullein). Read More

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http://dx.doi.org/10.1016/j.jpba.2019.01.031DOI Listing
March 2019
3 Reads

Association of ten gastrointestinal and other medical conditions with positivity to faecal occult blood testing in routine screening: a large prospective study of women in England.

Int J Epidemiol 2019 Jan 21. Epub 2019 Jan 21.

Cancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.

Background: In 2006, the Bowel Cancer Screening Programme (BCSP) in England began offering biennial faecal occult blood testing (FOBt) at ages 60-69 years. Although FOBt is aimed at detecting colorectal neoplasms, other conditions can affect the result. In a large UK prospective study, we examined associations, both before and after screening, between FOBt positivity and 10 conditions that are often associated with gastrointestinal bleeding. Read More

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http://dx.doi.org/10.1093/ije/dyy271DOI Listing
January 2019
2 Reads

Day-surgery stapled prolassectomy: a "ten minutes job".

Ann Ital Chir 2018 ;89:552-555

Introduction: Accordingly with the new physiopathologic insights of the 70s and 80s, hemorrhoidal disease appears to originate not much from venous hyperplasia but rather from a progressive deterioration of connective and support tissues with subsequent venous and mucosal prolapse. In the late 90s a new surgical technique for a more physiological treatment of hemorrhoids was introduced: stapled prolassectomy.

Materials And Methods: Between October 2017 and June 2018 we performed 50 hemorrhoidal stapled prolassectomies under local-regional anesthesia. Read More

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January 2018
5 Reads

The Author Replies.

Dis Colon Rectum 2019 02;62(2):e8-e9

Department of Surgery, Dartmouth-Hitchcock Medical Center, Lebanon, NH, Geisel School of Medicine, Lebanon, NH.

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http://dx.doi.org/10.1097/DCR.0000000000001284DOI Listing
February 2019
2 Reads

Should Hemorrhoids and Chronic Anal Fissure Be Treated as Medical Disorders? A Rational Way to Move Forward.

Authors:
Pankaj Garg

Dis Colon Rectum 2019 02;62(2):e8

Garg Fistula Research Institute, Panchkula, Haryana, India.

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http://dx.doi.org/10.1097/DCR.0000000000001283DOI Listing
February 2019
3 Reads

Evaluating the Accuracy of Hemorrhoids: Comparison Among Specialties and Symptoms.

Dis Colon Rectum 2019 Jan 8. Epub 2019 Jan 8.

Division of Colorectal Surgery, Department of Surgery, University Hospitals Cleveland Medical Center, Cleveland, Ohio.

Background: A large proportion of patients with anorectal complaints are referred to colorectal surgeons with the label of hemorrhoids.

Objective: The purpose of this study was to review presenting symptoms and frequency of accurate diagnosis, as well as to analyze determinants of misdiagnosis to guide educational endeavors.

Design: This was a retrospective study. Read More

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http://dx.doi.org/10.1097/DCR.0000000000001315DOI Listing
January 2019
2 Reads

[Quality indicators in the treatment of hemorrhoids].

Authors:
J Jongen V Kahlke

Chirurg 2019 Jan 11. Epub 2019 Jan 11.

Proktologische Praxis Kiel, Beselerallee 67, 24105, Kiel, Deutschland.

Background: A quality indicator is a quantitative measure that can be used to monitor and evaluate the quality of certain operative procedures that may influence the result of a therapy. An indicator is not a direct measure of quality, it is merely a tool to evaluate the performance of procedures and can indicate potential problem areas.

Material And Methods: A literature search was performed for parameters which could be included as indicators of quality in the treatment of hemorrhoids. Read More

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http://dx.doi.org/10.1007/s00104-018-0787-yDOI Listing
January 2019

Rubber Band Ligation of Hemorrhoids is often a Necessary Complement in the Management of Hemorrhagic Radiation Proctitis.

Scand J Surg 2019 Jan 11:1457496918822619. Epub 2019 Jan 11.

1 Department of Colorectal Surgery, Royal Prince Alfred Hospital, Sydney, NSW, Australia.

Background:: Management of radiation proctitis presents a treatment challenge. Limited data exist on the management of symptomatic hemorrhoids in radiated patients. This study aims to present a practical approach to the management of radiation proctitis, particularly in patients with synchronous hemorrhoids. Read More

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http://dx.doi.org/10.1177/1457496918822619DOI Listing
January 2019
1 Read

Doppler-guided transanal hemorrhoidal dearterilization versus conventional hemorrhoidectomy for treatment of hemorrhoids - early and long-term postoperative results.

BMC Surg 2019 Jan 10;19(1). Epub 2019 Jan 10.

Department of General and Hepato-pancreatic Surgery, University Hospital "Alexandrovska", 1 Georgi Sofiiski Str, 1431, Sofia, Bulgaria.

Background: A variety of effective methods for treatment of hemorrhoids has been proposed. In recent years, there has been an increasing number of studies comparing transanal hemorrhoidal dearterilization (THD) and conventional hemorrhoidectomy (CH), but the focus of most studies has been about the early postoperative results. The data about long-term outcomes is still limited. Read More

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http://dx.doi.org/10.1186/s12893-019-0469-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327383PMC
January 2019
4 Reads

European Society of Coloproctology Core Outcome Set for haemorrhoidal disease: an international Delphi study among healthcare professionals.

Colorectal Dis 2019 Jan 9. Epub 2019 Jan 9.

Department of Surgery and Colorectal Surgery, Maastricht University Medical Center +, Maastricht, The Netherlands.

Aim: There is considerable heterogeneity in outcomes in studies reporting on the treatment of haemorrhoidal disease (HD). The aim of this study was to develop a Core Outcome Set (COS) for HD in cooperation with the European Society of Coloproctology.

Method: A Delphi study was performed according to the Outcome Measures in Rheumatology (OMERACT) methodology. Read More

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http://dx.doi.org/10.1111/codi.14553DOI Listing
January 2019
4 Reads

Perianal infectious dermatitis: An underdiagnosed, unremitting and stubborn condition.

World J Clin Pediatr 2018 Oct 25;7(4):89-104. Epub 2018 Oct 25.

2 Department of Pediatrics, "Iuliu Hatieganu" University of Medicine and Pharmacy, Emergency Hospital for Children, Cluj-Napoca 400177, Romania.

Perianal infectious dermatitis (PID) represents a superficial inflammation of the perianal skin, which is of bacterial origin (classically, ). This narrative review aims to critically review and summarize the available scientific literature regarding pediatric PID, being the first of its kind, to the best of the author's knowledge. It also reports the first cases of Romanian children with PID. Read More

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http://dx.doi.org/10.5409/wjcp.v7.i4.89DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321840PMC
October 2018
8 Reads

Prospective Randomized Trial Comparing HAL-RAR Versus Excisional Hemorrhoidectomy: Postoperative Pain, Clinical Outcomes, and Quality of Life.

Surg Innov 2019 Jan 9:1553350618822644. Epub 2019 Jan 9.

1 Hospital Plató, Barcelona, Spain.

Purpose: To compare outcomes of hemorrhoid artery ligation with recto-anal repair (HAL-RAR) and excisional hemorrhoidectomy (EH). The primary objective was to compare postoperative pain, and the secondary objectives were the following: symptom resolution rates, postoperative morbidity, recurrence, and changes in quality of life.

Method: Prospective randomized controlled trial, including 40 patients with grades III-IV hemorrhoids who were allocated 1:1 to HAL-RAR and EH. Read More

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http://dx.doi.org/10.1177/1553350618822644DOI Listing
January 2019
9 Reads

Management of retrorectal hematoma after stapled transanal rectal resection for prolapsed hemorrhoids associated with occult rectal prolapse and obstructed defecation syndrome.

Tech Coloproctol 2018 12 6;22(12):987-988. Epub 2018 Dec 6.

AUSL della Romagna, Department of General Surgery, Ospedale per gli Infermi, Faenza, Italy.

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http://dx.doi.org/10.1007/s10151-018-1900-4DOI Listing
December 2018
2 Reads

Stapled Hemorrhoidectomy Versus Transanal Hemorrhoidal Dearterialization in the Treatment of Hemorrhoids: An Updated Meta-Analysis.

Surg Laparosc Endosc Percutan Tech 2018 Dec 11. Epub 2018 Dec 11.

Department of Anorectal Surgery, First Affiliated Hospital of Nanjing University of Traditional Chinese Medicine (TCM), Qinhuai District, Nanjing, Jiangsu Province.

This meta-analysis aimed to compare the clinical outcomes of stapled hemorrhoidectomy (SH) and transanal hemorrhoidal dearterialization (THD) for treating hemorrhoidal disease. Randomized control trials (RCTs) comparing SH with THD were searched in databases, including MEDLINE, PubMed, Web of Science, EMBASE, and the Cochrane Library database. Nine RCTs, with 1077 patients, were included in this meta-analysis. Read More

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http://dx.doi.org/10.1097/SLE.0000000000000612DOI Listing
December 2018
2 Reads

[The first experience of har-rar and radiofrequency ablation for hemorrhoidal disease treatment in hospitalization replacement environment].

Khirurgiia (Mosk) 2018 (11):53-59

Clinical Diagnostic Center of PAO 'Gazprom', Moscow, Russia.

Aim: To analyze advisability of HAL-RAR combined with radiofrequency ablation for hemorrhoidal disease under stationary substitution conditions.

Material And Methods: There were 152 patients. Technical features of this procedure are presented. Read More

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http://dx.doi.org/10.17116/hirurgia201811153DOI Listing
January 2018

[Recurrent thrombosed external hemorrhoids due to L-asparaginase administration in a Philadelphia chromosome-positive acute lymphoblastic leukemia patient].

Rinsho Ketsueki 2018;59(11):2413-2417

Department of Pediatrics, Kurashiki Central Hospital.

A 13-year-old female developed L-asparaginase (L-ASP) -associated thrombosed external hemorrhoids (TEH) during chemotherapy for Philadelphia chromosome-positive acute lymphoblastic leukemia. While undergoing induction therapy combined with imatinib, she experienced intense anal pain a day after the four-time administration of L-ASP. The anal verge contained painful bluish hemorrhoids, which reportedly were absent before the therapy commencement. Read More

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http://dx.doi.org/10.11406/rinketsu.59.2413DOI Listing
January 2018
2 Reads

Allergic Contact Dermatitis and Autoeczematization to Proctosedyl® Cream and Proctomyxin® Cream.

Case Rep Dermatol 2018 Sep-Dec;10(3):238-246. Epub 2018 Oct 24.

Department of Dermatology, University of Ottawa, Ottawa, Ontario, Canada.

Proctosedyl® and Proctomyxin® are two commonly prescribed hemorrhoid therapies. Their topical application to the perianal region may be complicated by a local allergic contact dermatitis and subsequent autoeczematization reaction. We present three cases of an autoeczematization (ID) reaction to varying topical allergens found in Proctosedyl®/Proctomyxin®. Read More

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http://dx.doi.org/10.1159/000486475DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276736PMC
October 2018
4 Reads

Skin anti-inflammatory activity of rose petal extract () through reduction of MAPK signaling pathway.

Food Sci Nutr 2018 Nov 25;6(8):2560-2567. Epub 2018 Oct 25.

Korea Food Research Institute Wanju-gun Korea.

The aim of this study was to investigate the skin anti-inflammatory activity of rose petal extract (RPE) and the mechanisms underlying this phenomenon. Recently, flowers have been considered as dietary resources owing to their biological activities, such as inhibition of nephritis and hemorrhoids. The plant exerts various biological functions, including antioxidant and anti-microbiological activities. Read More

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http://doi.wiley.com/10.1002/fsn3.870
Publisher Site
http://dx.doi.org/10.1002/fsn3.870DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261181PMC
November 2018
20 Reads

Effects of Stapled Hemorrhoidopexy on Anorectal Function: A Prospective Randomized Controlled Trial.

Iran J Med Sci 2018 Nov;43(6):581-586

Colorectal Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.

Background: Stapled hemorrhoidopexy is a safe and acceptable alternative to traditional hemorrhoidectomy with shorter hospital stay, better satisfaction, and less postoperative pain. There have, however, been reports on early and late complications. Therefore, the present study was designed to assess the impact of stapled hemorrhoidopexy on anorectal function and continence. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230943PMC
November 2018
12 Reads

Partial Stapled Hemorrhoidopexy Versus Circumferential Stapled Hemorrhoidopexy for Grade III to IV Prolapsing Hemorrhoids: A Randomized, Noninferiority Trial.

Dis Colon Rectum 2019 02;62(2):223-233

Guangdong Institute of Gastroenterology, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.

Background: Long-term outcomes and efficacy of partial stapled hemorrhoidopexy are not known.

Objective: The purpose of this study was to compare the long-term clinical efficacy and safety of partial stapled hemorrhoidopexy with circumferential stapled hemorrhoidopexy.

Design: This was a parallel group, randomized, noninferiority clinical trial. Read More

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http://dx.doi.org/10.1097/DCR.0000000000001261DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365260PMC
February 2019
4 Reads

Estimating disease burden using Internet data.

Health Informatics J 2018 Nov 29:1460458218810743. Epub 2018 Nov 29.

The University of North Carolina at Charlotte, USA; Mayo Clinic, USA.

Data on disease burden are often used for assessing population health, evaluating the effectiveness of interventions, formulating health policies, and planning future resource allocation. We investigated whether Internet usage and social media data, specifically the search volume on Google, page view count on Wikipedia, and disease mentioning frequency on Twitter, correlated with the disease burden, measured by prevalence and treatment cost, for 1633 diseases over an 11-year period. We also applied least absolute shrinkage and selection operator to predict the burden of diseases. Read More

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http://dx.doi.org/10.1177/1460458218810743DOI Listing
November 2018
2 Reads

Prolapsing mucosal fold: largest reported, presenting with major haemorrhage.

J Surg Case Rep 2018 Nov 22;2018(11):rjy312. Epub 2018 Nov 22.

Department of Surgery, Epworth Health, Box Hill, Victoria, Australia.

Prolapsing mucosal folds are uncommon benign colonic lesions that when inflamed may macroscopically resemble, and be confused with, an adenomatous or hyperplastic polyp. They are usually small and rarely cause symptoms. We report the case of a 55-year-old female admitted to hospital following six episodes of significant rectal bleeding. Read More

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http://dx.doi.org/10.1093/jscr/rjy312DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249423PMC
November 2018
4 Reads

Bipolar radiofrequency-induced thermotherapy of haemorrhoids: a 10-year experience.

Rozhl Chir 2018 ;97(9):419-422

Introduction: Bipolar radiofrequency-induced thermotherapy of advanced stage haemorrhoid disease has been used successfully at the Atlas Hospital in Zlin for ten years. The aim of this study was to evaluate long-term outcomes of the method.

Method: RFITTH is bipolar radiofrequency-induced thermotherapy of haemorrhoidal diseases. Read More

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January 2018
12 Reads

Aerobic vaginitis in late pregnancy and outcomes of pregnancy.

Eur J Clin Microbiol Infect Dis 2019 Feb 22;38(2):233-239. Epub 2018 Nov 22.

Department of Gynecology and Obstetrics, Tianjin Medical University General Hospital, No.154 Anshan Road, Heping District, Tianjin, 300052, China.

The purpose of this study was to investigate the risk factors and pregnancy outcomes for aerobic vaginitis (AV) in late pregnancy. A total of 624 pregnant women who were treated in the perinatal unit at Tianjin Medical University General Hospital and 365 nonpregnant women who were evaluated at a health management center from January 2015 to June 2016 were recruited for this case-control study. A questionnaire covering personal hygiene habits and sociodemographic factors was administered to pregnant women to analyze risk factors for AV. Read More

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http://dx.doi.org/10.1007/s10096-018-3416-2DOI Listing
February 2019
15 Reads

Topical Analgesia with Lidocaine Plus Diclofenac Decreases Pain in Benign Anorectal Surgery: Randomized, Double-blind, and Controlled Clinical Trial.

Clin Transl Gastroenterol 2018 Nov 23;9(11):210. Epub 2018 Nov 23.

Drug Development Services, Pharmacy and Pharmaceutical Technology and Physical Chemistry Department, University of Barcelona, Barcelona, Spain.

Objective: The aim of this study is to evaluate the efficacy and safety of a topical formulation containing lidocaine plus diclofenac (CLIFE1) compared to lidocaine (CLIFE2), to decrease pain in benign anorectal surgery (BARS) to date not evaluated. More than 50% of patients undergoing BARS, especially hemorrhoidectomy, suffer from moderate and severe postoperative pain. This remains an unresolved problem that could be addressed with the new CLIFE1 topical treatment. Read More

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http://dx.doi.org/10.1038/s41424-018-0075-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6250696PMC
November 2018
13 Reads

Management of disseminated intravascular coagulation in a patient with hepatic angiosarcoma: A case report.

Medicine (Baltimore) 2018 Nov;97(47):e13321

Hematology Division, Massachusetts General Hospital, Boston, MA.

Rationale: Hepatic angiosarcoma is a rare endothelial cell tumor that may lead to concurrent consumptive coagulopathies including disseminated intravascular coagulation (DIC). This report details a multifaceted approach to managing DIC in a patient with advanced-stage hepatic angiosarcoma, which continued to progress after a brief response to taxane-based chemotherapy.

Patient Concerns: A 55-year-old man with a recent history of hemorrhoids and hemarthroses presented with acute rectal bleeding. Read More

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http://dx.doi.org/10.1097/MD.0000000000013321DOI Listing
November 2018
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Therapeutic Potential of : A Review on Its Traditional Uses, Phytochemistry, Pharmacology and Toxicological Aspects.

Front Pharmacol 2018 22;9:1177. Epub 2018 Oct 22.

Department of Pharmacology, School of Pharmacy and Technology Management, SVKM's NMIMS, Dhule, India.

(Cucurbitaceae), a perennial plant grows mainly in India, Southeast Asia, China, Japan, Egypt, and other parts of Africa, it is widely used in the traditional Indian medicinal system to treat various health conditions. The plant has been used in jaundice, diabetes, hemorrhoids, dysentery, headache, ringworm infection, and leprosy. More than 50 chemical compounds have been isolated from a plant which mainly comprises flavonoids, anthraquinones, proteins, fatty acids, saponin triterpene, volatile components, and other phytoconstituents. Read More

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http://dx.doi.org/10.3389/fphar.2018.01177DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232903PMC
October 2018
13 Reads

Validity and reliability of the measure yourself medical outcome profile 2 (MYMOP2) questionnaire among Turkish patients having anorectal disorders.

Turk J Gastroenterol 2019 01;30(1):28-32

Department of Physiotherapy and Rehabilitation, Bahçesehir University School of Health Sciences, İstanbul, Turkey.

Background/aims: Measure Yourself Medical Outcome Profile 2 (MYMOP2) is a patient-generated outcome measure allowing patients to select the problems that are the most important to them and that they want to address, and it measures the effects of the problem from a wide range of health care interventions. This study aimed to translate the questionnaire into Turkish language (Turkish MYMOP-TMYMOP) and add this clinically useful measure to Turkish medical practice by assessing its validity and reliability.

Materials And Methods: Fifty volunteers with anorectal disorders were prospectively included into the study. Read More

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http://dx.doi.org/10.5152/tjg.2018.17859DOI Listing
January 2019
3 Reads

Hemorrhoidal Disease Symptom Score and Short Health ScaleHD: New Tools to Evaluate Symptoms and Health-Related Quality of Life in Hemorrhoidal Disease.

Dis Colon Rectum 2019 Mar;62(3):333-342

Department of Surgery, Holbaek Hospital, Holbaek, Denmark.

Background: There are no adequately validated tools to evaluate symptoms or disease-specific health-related quality of life in hemorrhoidal disease.

Objective: The purpose of this study was to assess validity, reliability, and responsiveness of a symptom score of patient-reported pain, itching, bleeding, soiling, and prolapse (Hemorrhoidal Disease Symptom Score). In addition, the study set out to assess reliability and responsiveness of an instrument to measure health-related quality of life in patients with hemorrhoids (Short Health ScaleHD), with 1 item in its 4 dimensions: symptom load, functional status, disease-specific worries, and general well-being. Read More

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http://dx.doi.org/10.1097/DCR.0000000000001234DOI Listing
March 2019
20 Reads