6,554 results match your criteria Hemorrhoids


Modulation of inflammatory pathways, medicinal uses and toxicities of Uvaria species: potential role in the prevention and treatment of inflammation.

Inflammopharmacology 2020 Jul 2. Epub 2020 Jul 2.

Drug and Herbal Research Centre, Faculty of Pharmacy, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, 50300, Kuala Lumpur, Malaysia.

The therapeutic efficacy of the contemporary anti-inflammatory drugs are well established; however, prolonged use of such can often lead to serious and life-threatening side effects. Natural product-based anti-inflammatory compounds with superior efficacy and minimum toxicity can serve as possible therapeutic alternatives in this scenario. Genus Uvaria is a part of Annonaceae family, while the majority of its species are widely distributed in tropical rain forest regions of South East Asia. Read More

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http://dx.doi.org/10.1007/s10787-020-00734-2DOI Listing

Single Stapled Parachute Technique (SSPT) for grade IV prolapsed haemorrhoids - Video Vignette.

Colorectal Dis 2020 Jul 1. Epub 2020 Jul 1.

Department of Surgery, Università Vita Salute San Raffaele, Milan, Italy.

Prolapse represents one of the most common indications for hemorrhoidectomy. In 1998, Longo proposed the Procedure for Prolapse and Hemorrhoids (PPH) using a specially designed circular stapler. It aims to preserve the hemorrhoidal plexus by performing a circumferential mucosectomy restoring it to its original anatomical position. Read More

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http://dx.doi.org/10.1111/codi.15226DOI Listing

PREVALENCE AND FACTORS ASSOCIATED WITH CONSTIPATION IN PREMENOPAUSAL WOMEN: A COMMUNITY-BASED STUDY.

Arq Gastroenterol 2020 Apr-Jun;57(2):188-192

Universidade Federal do Rio Grande do Norte, Faculdade de Ciências da Saúde de Trairi (FACISA), Santa Cruz, RN, Brasil.

Background: Intestinal constipation is characterized by problems related to evacuation, and presents high prevalence in the female gender. This condition has demonstrated negative effects on the development of daily activities, causing damage to the physical and emotional well-being of individuals who are diagnosed with it. Studies that investigate what health impairments intestinal constipation can cause are scarce in the literature. Read More

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http://dx.doi.org/10.1590/S0004-2803.202000000-36DOI Listing
January 2020

Antihemorrhoidal activity of organic acids of Capsella bursa-pastoris on croton oil-induced hemorrhoid in rats.

J Food Biochem 2020 Jun 25:e13343. Epub 2020 Jun 25.

Department of Animal Science, Ataturk University Veterinary Faculty, Erzurum, Turkey.

This study was aimed to investigate the antihemorrhoidal effects of ethanol (CBE) and water extracts (CBW) of Capsella bursa-pastoris, an edible plant and a precipitant (CBW-1) obtained from the CBW in croton oil (CO)-induced hemorrhoid model in rats. CBW-1 was contain three organic acids, citric acid (36.09%), malic acid (35. Read More

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http://dx.doi.org/10.1111/jfbc.13343DOI Listing

Review of American Society of Colon and Rectal Surgeons Clinical Practice Guidelines for the Management of Hemorrhoids.

Authors:
Roberta Muldoon

JAMA Surg 2020 Jun 17. Epub 2020 Jun 17.

Vanderbilt University, Division of General Surgery, Section of Colon and Rectal surgery, Nashville, Tennessee.

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http://dx.doi.org/10.1001/jamasurg.2020.0788DOI Listing

Stapled hemorrhoidopexy for grade III hemorrhoids with circular prolapse - a video vignette.

Colorectal Dis 2020 Jun 25. Epub 2020 Jun 25.

Institute of Clinical Medicine Faculty of Medicine, Vilnius University, Vilnius, Lithuania.

Hemorrhoidal disease (HD) is one of the most common anorectal disorders seen in the proctology practise [1]. Stapled hemorrhoidopexy (SH) has been reported as a highly effective alternative to other invasive approaches [2]. However, a recently published randomized controlled trial concluded that SH was worse for recurrence rates, symptoms, re-interventions and quality-of-life measures compared to traditional haemorrhoidectomy [3]. Read More

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http://dx.doi.org/10.1111/codi.15216DOI Listing

Primary anorectal malignant melanoma with laparoscopic abdominoperineal resection: a case study and review of the relevant literature.

Int Cancer Conf J 2020 Jul 17;9(3):116-122. Epub 2020 Apr 17.

Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

ARMM is a disease with a poor prognosis. ARMM is often diagnosed at an advanced stage, and the 5-year survival rate of ARMM is < 20%. Although the number of case reports on ARMM is gradually increasing, the optimal treatment strategy for ARMM remains controversial. Read More

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http://dx.doi.org/10.1007/s13691-020-00401-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297936PMC

Cap-assisted endoscopic sclerotherapy for internal hemorrhoids: technique protocol and study design for a multi-center randomized controlled trial.

Ther Adv Gastrointest Endosc 2020 Jan-Dec;13:2631774520925636. Epub 2020 Jun 5.

Professor, Medical Center for Digestive Diseases, Second Affiliated Hospital of Nanjing Medical University, 121 Jiangjiayuan, Nanjing 210011, China.

Background: Cap-assisted endoscopic sclerotherapy is a new interventional therapy for internal hemorrhoids and rectal prolapse under colonoscopy. The proper length of the endoscopic injection needle is the core for performing cap-assisted endoscopic sclerotherapy well with more benefits and less complications. However, no data are currently available to guide endoscopists to consider the length of injection needle before cap-assisted endoscopic sclerotherapy. Read More

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http://dx.doi.org/10.1177/2631774520925636DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7278306PMC

Endoscopic Findings in Patients Under the Age of 40 Years with Hematochezia in Singapore.

Clin Endosc 2020 Jun 18. Epub 2020 Jun 18.

Department of Colorectal Surgery, Singapore General Hospital, Singapore.

Background/aims: Sigmoidoscopy is performed in most medical centers to evaluate the distal colons of young adults presenting with hematochezia who are at risk of developing proximal lesions. Colonoscopies offer more complete evaluations but are associated with a higher incidence of complications and possible low yield.

Methods: An analysis was conducted on colonoscopies performed in our center on patients 40 years of age or younger. Read More

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http://dx.doi.org/10.5946/ce.2019.029DOI Listing

Implementation of General Surgery Care into a Student-Run Free Clinic.

J Surg Res 2020 Jun 15;255:71-76. Epub 2020 Jun 15.

Vanderbilt University Medical Center, Department of General Surgery, Nashville, Tennessee. Electronic address:

Background: Student-run free clinics (SRFCs) provide medical care to uninsured, and surgical issues are often outside the normal scope of care of these clinics. The Shade Tree Clinic (STC) is an SRFC serving 300 patients with complex medical conditions. This study describes the implementation and efficacy of a General Surgery Specialty Clinic in this setting. Read More

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http://dx.doi.org/10.1016/j.jss.2020.05.031DOI Listing

Croton urucurana Baillon stem bark ointment accelerates the closure of cutaneous wounds in knockout IL-10 mice.

J Ethnopharmacol 2020 Jun 10;261:113042. Epub 2020 Jun 10.

Department of Biochemistry and Molecular Biology, Viçosa Federal University, 35570-900, Viçosa, Minas Gerais, Brazil. Electronic address:

Ethnopharmacological Relevance: Croton urucurana Baill. (Euphorbiaceae) is a plant used in Brazilian popular medicine for the treatment of wound healing, inflammatory diseases, gastritis, infections, and hemorrhoids.

Aim: The present study aimed to evaluate the in vivo wound healing activity of an ointment based on ethanolic extract of C. Read More

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http://dx.doi.org/10.1016/j.jep.2020.113042DOI Listing

Polidocanol versus phenol in oil injection sclerotherapy in treatment of internal hemorrhoids: A randomized controlled trial.

Turk J Gastroenterol 2020 May;31(5):378-383

Department of Surgery, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, India.

Background/aims: Management of Haemorrhoids is suboptimal and is largely based on traditional practices in the Indian population. Though injection sclerotherapy is a well-accepted treatment modality in early grade haemorrhoids, there is no consensus on the effectiveness of the drugs used for sclerotherapy. The study was done to compare the safety and efficacy of a standard sclerosant (polidocanol) and the conventionally used phenol in oil in bleeding grade-1 and 2 internal haemorrhoids. Read More

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http://dx.doi.org/10.5152/tjg.2020.19276DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7289163PMC

Transanal hemorrhoidal dearterialization: Lessons learned from a personal series of 200 consecutive cases and a proposal for a tailor-made procedure.

Ann Med Surg (Lond) 2020 Jul 29;55:207-211. Epub 2020 May 29.

Department of Gastroenterology, Digestive and Colorectal Surgery Division, University of São Paulo School of Medicine, Av. Doutor Enéas de Carvalho Aguiar, 255, 05409-000, São Paulo, Brazil.

Background: Transanal hemorrhoidal dearterialization (THD) is an effective treatment for hemorrhoidal disease (HD). However, the surgical technique is not standardized and the results for advanced HD are controversial. The aim of this study was to assess surgical outcomes after a long follow-up and compare total and partial mucopexy. Read More

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http://dx.doi.org/10.1016/j.amsu.2020.05.036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7272515PMC

[E.coli bacterial suspension in the treatment of hemorrhoids].

Khirurgiia (Mosk) 2020 (5):102-108

A.I. Evdokimov Moscow State University of Medicine and Dentistry of the Ministry of Health of Russia, Moscow, Russia.

Hemorrhoidal disease is the most common proctologic disease and the search for new treatment methods, as well as an in-depth understanding of the mechanisms underlying effects of well-known agents on disease pathogenesis still remain relevant. There have been long recognized the effects of the bacterial culture suspension (BCS) as a therapeutic means eliciting decreased exudation during inflammation, wound healing, tissue regeneration, and stimulated immunity. Here, based on recent findings related to innate and adaptive immune cells, we set out to present mechanisms accounting for some effects coupled to commensal bacteria, particularly inactivated BCS, which are important for understanding pathogenesis-related action of drug Posterisan and Posterisan forte, and outline their broad application in therapy of hemorrhoids. Read More

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http://dx.doi.org/10.17116/hirurgia2020051102DOI Listing

Predictive factors of rectal hemorrhage in patients with localized prostate cancer who underwent low-dose-rate brachytherapy.

Int J Clin Oncol 2020 Jun 5. Epub 2020 Jun 5.

Department of Urology, Graduate School of Medicine, Gifu University, 1-1 Yanagido, Gifu, 501-1194, Japan.

Background: This study aimed to evaluate the association between clinical covariates or the prescribed radiation dose for the prostate and rectal hemorrhage in patients with prostate cancer (PCa) who received iodine-125 low-dose-rate brachytherapy (LDR-BT group) or the combination of LDR-BT and external beam radiation therapy (CMT group).

Methods And Materials: In this retrospective study, we reviewed the clinical records of 298 consecutive PCa patients with clinical stage T1c/T2 who underwent LDR-BT between August 2004 and August 2016 at a single institution. The prescribed minimum peripheral doses were 145 Gy for the LDR-BT group and 104 Gy for the CMT group. Read More

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http://dx.doi.org/10.1007/s10147-020-01713-xDOI Listing

Hemorrhoidal Artery Ligation Operations-Recto-Anal Repair (HALO-RAR) Procedure for Recurrent Haemorrhoids: Excellent Patient Satisfaction.

Cureus 2020 May 3;12(5):e7944. Epub 2020 May 3.

General Surgery, University Hospitals of Derby and Burton National Health Service (NHS) Foundation Trust, Burton on Trent, GBR.

Background Haemorrhoid is the most common anal canal disease. Treatments may vary from non-invasive to invasive depending on the symptoms. Haemorrhoidectomy has been widely used. Read More

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http://dx.doi.org/10.7759/cureus.7944DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7266563PMC

Hemorrhoidectomy for elderly patients aged 75 years or more, before and after studies.

Ann Med Surg (Lond) 2020 Jul 16;55:88-92. Epub 2020 May 16.

Department of Gastroenterological and Transplant Surgery, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.

Background: The incidence of hemorrhoids requiring hemorrhoidectomy among the elderly has been increasing. Old age is sometimes considered a contraindication for surgery. The relationship between age and complications of hemorrhoidectomy for elderly patients is not well established. Read More

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http://dx.doi.org/10.1016/j.amsu.2020.04.045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251490PMC

A Rare Clinical Presentation of Metastatic Crohn's Disease.

Cureus 2020 May 26;12(5):e8285. Epub 2020 May 26.

Dermatology, Baylor College of Medicine, Houston, USA.

A 31-year-old female with a history of systemic lupus erythematous, IgA nephropathy, and psoriasis presented with a one-month history of a painful, pruritic rash under the bilateral breasts and in the genital region. Cutaneous examination revealed a large, tender ulcer under the left breast with a shiny erythematous base and peripheral hypertrophic changes. Small ulcers were present on the bilateral inguinal folds, and the labia majora were edematous with multiple erythematous papules. Read More

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http://dx.doi.org/10.7759/cureus.8285DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7250390PMC

Assessment of pediatric Crohn's disease activity: validation of the magnetic resonance enterography global score (MEGS) against endoscopic activity score (SES-CD).

Abdom Radiol (NY) 2020 May 26. Epub 2020 May 26.

Department of Pathology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China.

Objective: The aim of this study is to evaluate the ability of magnetic resonance enterography global score (MEGS) to diagnose the activity of pediatric Crohn's disease (CD) and its correlation with endoscopic activity score.

Materials And Methods: 70 pediatric CD patients (between the ages of 6 and 17) were enrolled who underwent ileocolonoscopy and magnetic resonance enterography (MRE) within 7 days. The simplified endoscopic activity score for Crohn's disease (SES-CD) and MEGS were acquired in the terminal ileum. Read More

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http://dx.doi.org/10.1007/s00261-020-02590-8DOI Listing

YouTube as a source of patients and specialists' information on hemorrhoids and hemorrhoid surgery.

Rev Recent Clin Trials 2020 May 24. Epub 2020 May 24.

Proctology and Pelvic Floor Clinical Centre, Cisanello University Hospital, Pisa. Italy.

Background: In the past, most people sought medical information by consulting heath care professionals. Nowadays, many people started to use online resources to access medical information.

Objective: The study aims to investigate whether YouTube videos on hemorrhoids and hemorrhoid surgery can be a useful e-learning source for the general population, surgical trainees and specialists. Read More

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http://dx.doi.org/10.2174/1574887115666200525001619DOI Listing

Delayed benign surgery during the COVID-19 pandemic: the other side of the coin.

Br J Surg 2020 07 22;107(8):e258. Epub 2020 May 22.

Department of Medical and Surgical Sciences, University of Catanzaro, Catanzaro, Italy.

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http://dx.doi.org/10.1002/bjs.11712DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7280568PMC

Recovery from hemorrhoids and anal fissure without surgery.

Turk J Gastroenterol 2020 Apr;31(4):289-294

Department of General Surgery, Medeniyet University, Goztepe Training and Research Hospital, Istanbul, Turkey.

Background/aims: An anal fissure (AF) is a linear tear in the distal anal canal and is one of the most common causes of anal pain. Hemorrhoidal disease (HD) is a symptomatic growth and distal displacement of normal anal cushions. Numerous studies have addressed the contributing factors of these conditions, yet the results remain controversial. Read More

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http://dx.doi.org/10.5152/tjg.2020.19183DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7236649PMC

Mucopexy-Recto Anal Lifting (MuRAL) in managing obstructed defecation syndrome associated with prolapsed hemorrhoids and rectocele: preliminary results.

Ann Surg Treat Res 2020 May 28;98(5):277-282. Epub 2020 Apr 28.

Day/Week Surgery Unit, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

Purpose: Treatment of rectocele associated with prolapsed hemorrhoids is a debated topic. Transanal stapling achieved good midterm results in patients with symptoms of obstructed defecation, nevertheless a number of severe complications have been reported. The aim of this study was to evaluate the safety and efficacy of a new endorectal manual technique in patients with obstructed defecation due to the combination of muco-hemorrhoidal prolapse and rectocele. Read More

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http://dx.doi.org/10.4174/astr.2020.98.5.277DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7200604PMC

Comparison of Centella with Flavonoids for Treatment of Symptoms in Hemorrhoidal Disease and After Surgical Intervention: A Randomized Clinical Trial.

Sci Rep 2020 May 14;10(1):8009. Epub 2020 May 14.

Department of General Surgery and Specialties "Paride Stefanini", Sapienza University of Rome, Rome, 00161, Italy.

Phlebotonics' effects were evaluated to reduce time-to-stop bleeding and anal irritation in 130 patients who complained of hemorrhoidal disease (HD); bleeding and pain after hemorrhoidectomy (31 patients) and hemorrhoidal thrombosis (34 patients) in the short time. Sixty patients were randomized to receive the routine treatment (both conservative and surgical) (control Group C). The treated group (both conservative and surgical) was divided into two subgroups: one treated with flavonoids (Group A, n = 73), the other with Centella (Group B, n = 66). Read More

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http://dx.doi.org/10.1038/s41598-020-64772-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7224176PMC

Micronized Purified Flavonoid Fraction in Hemorrhoid Disease: A Systematic Review and Meta-Analysis.

Adv Ther 2020 Jun 12;37(6):2792-2812. Epub 2020 May 12.

State Scientific Center of Coloproctology, Ministry of Health of Russian Federation, Moscow, Russia.

Introduction: Hemorrhoidal disease (HD) is a common and recurrent problem for many adults worldwide. Venoactive drugs, such as micronized purified flavonoid fraction (MPFF; Daflon), have been used to treat HD and their clinical benefits have been demonstrated in previous meta-analyses of clinical trials. The aim of this study was to evaluate the efficacy of MPFF across the broader spectrum of signs and symptoms following treatment of patients with HD. Read More

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http://dx.doi.org/10.1007/s12325-020-01353-7DOI Listing

Scoring systems as outcomes assessment of the treatments for haemorrhoidal disease: a systematic review of the literature.

Int J Colorectal Dis 2020 Jun 7;35(6):1015-1024. Epub 2020 May 7.

Division of Digestive Surgery, Geneva University Hospitals and Medical School, Rue Gabrielle-Perret-Gentil 4, 1211, Geneva, Switzerland.

Purpose: The comparison between haemorrhoidal treatments is still unclear. Attempts have been made to adopt a unifying postoperative scoring system and thus ensure adequate comparison between clinical trials. We aimed to systematically review the available outcome scores of haemorrhoidal treatment. Read More

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http://dx.doi.org/10.1007/s00384-020-03603-0DOI Listing
June 2020
2.449 Impact Factor

The management of Hemorrhoidal Disease by Dearterialization and Mucopexy.

Rev Recent Clin Trials 2020 May 5. Epub 2020 May 5.

Proctology Unit, Fondazione Policlinico Universitario "A. Gemelli" IRCCS, Rome. Italy.

Several minimally invasive surgical procedures have been recently developed to treat hemorrhoids without any excision. About 25 years ago, a non-excisional procedure providing doppler-guided ligation of the hemorrhoidal arteries has been proposed - named "hemorrhoidal dearterialization". The original technique has been modified over the years, and indications were expanded. Read More

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http://dx.doi.org/10.2174/1574887115666200506091306DOI Listing

Withdrawal Notice: Conservative Treatment of Haemorrhoids

Rev Recent Clin Trials 2020 05 5. Epub 2020 May 5.

S. Rita Clinic, Coloproctology Unit, Vercelli. Italy.

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http://dx.doi.org/10.2174/1574887115666200506090507DOI Listing

Molecular and Immunological Mechanisms Underlying the Various Pharmacological Properties of the Potent Bioflavonoid, Rutin.

Endocr Metab Immune Disord Drug Targets 2020 May 2. Epub 2020 May 2.

Department of Pharmaceutical Technology, School of Pharmacy, International Medical University (IMU), Bukit Jalil, Kuala Lumpur, 57000. Malaysia.

The application of medicinal plants has captured the interest of researchers in recent times due to their potent therapeutic properties and a better safety profile. The prominent role of herbal products in treating and preventing multiple diseases dates back to ancient history and most of the modern drugs today originated from its significant sources owing to their ability to control multiple targets via different signalling pathways. Among them, flavonoids consist of a large group of polyphenols, which are well known for their various therapeutic benefits. Read More

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http://dx.doi.org/10.2174/1871530320666200503053846DOI Listing

Evacuatory Dysfunction after Stapled Hemorrhoidopexy: A Case Report of Rectal Pocket Syndrome.

J Anus Rectum Colon 2020 28;4(2):85-88. Epub 2020 Apr 28.

Department of Pathology, Sapporo Higashi Tokushukai Hospital, Sapporo, Japan.

A 60 year-old male was referred to the authors' hospital with a persistent urge to defecate. The patient had undergone stapled hemorrhoidopexy (SH) for the treatment of prolapsed hemorrhoids approximately 10 years earlier. He started to have difficulty with defecation and a false sense of urgency shortly after the surgery. Read More

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http://dx.doi.org/10.23922/jarc.2019-024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7186010PMC

Evaluation of Mucopexy-Recto Anal Lifting (MuRAL): A New Method for Treating Hemorrhoids.

J Anus Rectum Colon 2020 28;4(2):51-58. Epub 2020 Apr 28.

Coloproctology Centre, Matsushima Hospital, Yokohama, Japan.

Objectives: Ligation and excision remain the commonly recognized standard surgical modality for treating hemorrhoids. Further, impediments to surgical treatment owing to social factors and the need for minimally invasive procedures and other confounders have resulted in the adoption of the mucopexy-recto anal lifting (MuRAL) method which is associated with favorable outcomes. The objective of this study was to describe the procedure and report the outcomes in patients who underwent MuRAL. Read More

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http://dx.doi.org/10.23922/jarc.2019-017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7186007PMC

Mid-Term Results of Superior Rectal Artery and Coils for Hemorrhoidal Embolization with Particles Bleeding.

Cardiovasc Intervent Radiol 2020 Jul 27;43(7):1062-1069. Epub 2020 Apr 27.

Sorbonne Paris Cité, Medicine Faculty, Paris Descartes University, Paris, France.

Objectives: To compare safety and clinical outcomes of embolization of the superior rectal arteries in patients with hemorrhoidal bleeding using particles and coils versus coils only.

Methods: We retrospectively reviewed data for patients undergoing embolization for chronic hemorrhoidal bleeding from January 2014 to April 2017. Embolization was performed with coils alone or with particles and coils. Read More

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http://dx.doi.org/10.1007/s00270-020-02441-5DOI Listing

Evaluating the ability of the Sodergren score to guide the management of internal haemorrhoidal disease.

Colorectal Dis 2020 Apr 26. Epub 2020 Apr 26.

Department of Surgery, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.

Aim: The Sodergren score was developed to objectively measure the severity of haemorrhoidal symptoms. This study aimed to determine if there was a difference in the Sodergren score between patients who were offered surgery and patients who underwent successful rubber band ligation of internal haemorrhoidal disease and to assess its performance in guiding management.

Method: This is a prospective, observational study. Read More

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http://dx.doi.org/10.1111/codi.15091DOI Listing

A rare case of musk anti-hemorrhoids ointment-induced symmetrical drug-related intertriginous and flexural exanthema.

Contact Dermatitis 2020 Apr 25. Epub 2020 Apr 25.

Department of Dermatology, the Third Affiliated Hospital of Chongqing Medical University, Chongqing, China.

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http://dx.doi.org/10.1111/cod.13574DOI Listing

Chronic Constipation in the Community: A National Survey of Australian Adults.

J Wound Ostomy Continence Nurs 2020 May/Jun;47(3):259-264

Barry L. Werth, PhD, Sydney Nursing School, University of Sydney, New South Wales, Australia. Murray J. Fisher, PhD, Sydney Nursing School, University of Sydney, New South Wales, Australia. Kylie A. Williams PhD, Discipline of Pharmacy, Graduate School of Health, University of Technology Sydney, New South Wales, Australia. Lisa G. Pont, PhD, Sydney Nursing School, University of Sydney, and Discipline of Pharmacy, Graduate School of Health, University of Technology Sydney, New South Wales, Australia.

Purpose: The aim of this study was to determine the prevalence of chronic constipation and identify factors associated with chronic constipation in community-dwelling adults.

Design: Cross-sectional study.

Methods: The target population was community-dwelling Australian adults; 1978 participants completed an online questionnaire exploring symptoms, management, and factors potentially associated with constipation. Read More

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http://dx.doi.org/10.1097/WON.0000000000000632DOI Listing
April 2020
1.000 Impact Factor

Safety and Efficacy of Proctosoll Allevia in the Management of Haemorrhoidal Disease in Adults: A Prospective Randomized Clinical Trial.

Rev Recent Clin Trials 2020 ;15(2):152-159

Proctology and Pelvic Floor Clinical Centre, Cisanello University Hospital, Pisa, Italy.

Introduction: Hemorrhoidal Disease (HD) is a very common anorectal disorder that affects millions of people around the world and represents a major medical and socioeconomic problem. The aim of the present study was to assess the safety and efficacy of Proctosoll Allevia® in patients affected by symptomatic HD in comparison with the results obtained from a control group.

Materials And Methods: From January to February 2019, all the patients referred to the outpatient clinic of Rajalakshmi Hospital, who were complaining of first or second degree hemorrhoidal symptoms, were enrolled in the study. Read More

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http://dx.doi.org/10.2174/1574887115666200421110107DOI Listing
January 2020

Molecular profiling of Peru Balsam reveals active ingredients responsible for its pharmaceutical properties.

Nat Prod Res 2020 Apr 21:1-6. Epub 2020 Apr 21.

Research Laboratory for Archaeology and the History of Art, University of Oxford, Oxford, UK.

Peru Balsam, a resinous substance derived from var. , has historically been used as a topical ointment for various skin conditions such as scabies, poorly healing wounds, eczema, and haemorrhoids. The ingredients responsible for these properties are not fully elucidated. Read More

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http://dx.doi.org/10.1080/14786419.2020.1753056DOI Listing

Metastatic Anorectal Melanoma.

J Gastrointest Surg 2020 Apr 20. Epub 2020 Apr 20.

Department of Histopathology, American Institute of Pathology and Laboratory Sciences, Hyderabad, India.

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http://dx.doi.org/10.1007/s11605-020-04604-8DOI Listing

Fundamentals of Anorectal Technical Skills: A Concise Surgical Skills Course.

Mil Med 2020 Apr 21. Epub 2020 Apr 21.

Division of General Surgery, Department of Surgery, Uniformed Services University of the Health Sciences (USUHS)/Walter Reed National Military Medical Center, 8901 Wisconsin Ave, Bethesda, MD 20889.

Introduction: Anorectal diseases, among the most common surgical conditions, are underrepresented in medical training. The Fundamentals of Anorectal Technical Skills course was developed to provide cost-effective formal training in diagnosis of common anorectal conditions and in commonly performed anorectal procedures using the theories of deliberative practice and perceptual and adaptive learning.

Materials And Methods: First- through third-year general surgery and internal medicine residents and third- and fourth-year medical students participated in a course consisting of didactic instruction and hands on skills stations. Read More

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http://dx.doi.org/10.1093/milmed/usaa070DOI Listing

Traditional Chinese medicine (Liang-Xue-Di-Huang Decoction) for hemorrhoid hemorrhage: Study Protocol Clinical Trial (SPIRIT Compliant).

Medicine (Baltimore) 2020 Apr;99(16):e19720

Nanjing University of Chinese Medicine, Changzhou Hospital of Traditional Chinese Medicine, Changzhou.

Background: Hemorrhoidal disease (HD) is one of the commonest proctologic condition in the general population. Medical therapy for HD has not been formally confirmed due to the inconsistent of results. Liang-Xue-Di-Huang Decoction, a kind of ancient Chinese classical prescription, has been used to treat HD from the 19th century in China. Read More

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http://dx.doi.org/10.1097/MD.0000000000019720DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7220198PMC

Colorectal Surgery Review for Primary Care Providers.

Mo Med 2020 Mar-Apr;117(2):154-158

Rakesh Hegde, MD, John M. Trombold, MD & José M. Dominguez, MD, MSMA member since 1996, are in the Department of Colon and Rectal Surgery, Ferrell-Duncan Clinic, CoxHealth, Springfield, Missouri.

Anorectal conditions are one of the most common problems evaluated by primary care physicians. Most patients present with rectal pain, rectal bleeding, or purulent drainage per rectum. Colorectal conditions have overlapping symptoms. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144705PMC

Emborrhoid in patients with portal hypertension and chronic hemorrhoidal bleeding: preliminary results in five cases with a new coiling release fashion "Spaghetti technique".

Radiol Med 2020 Apr 18. Epub 2020 Apr 18.

Interventional Radiology Department, Cardarelli Hospital, Via Cardarelli 9, 80100, Naples, Italy.

Purpose: This manuscript reports on a preliminary experience concerning emborrhoid in patients affected by cirrhotic portal hypertension; furthermore, a novel customized technique of coils release, named "Spaghetti technique," is described.

Materials And Methods: Five patients with chronic anemia due to internal hemorrhoidal bleeding and cirrhotic portal hypertension were treated. Clinics and hemoglobin values were evaluated to objectively assess clinical conditions up to 3 months follow-up. Read More

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http://dx.doi.org/10.1007/s11547-020-01194-yDOI Listing

The Italian paradox of flavonoid use for hemorrhoids.

Authors:
A Serventi

Tech Coloproctol 2020 06 17;24(6):613. Epub 2020 Apr 17.

Department of Surgery, Monsignor Galliano Hospital, Acqui Terme, AL, Italy.

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http://dx.doi.org/10.1007/s10151-020-02217-6DOI Listing

The role of routine flexible sigmoidoscopy in patients presenting with fistula-in-ano: an observational study.

BMC Res Notes 2020 Apr 16;13(1):214. Epub 2020 Apr 16.

Department of Surgery, Faculty of Medicine, University of Colombo, P.O. Box 271, Kynsey Road, Colombo 8, Western Province, Sri Lanka.

Objective: Flexible sigmoidoscopy is useful to look for an underlying aetiology in fistula-in-ano. This study was aimed to assess the yield of routine flexible sigmoidoscopy in patients presenting with fistula-in-ano. A retrospective analysis of 159 consecutive patients with fistula-in-ano who underwent routine flexible sigmoidoscopy was performed. Read More

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http://dx.doi.org/10.1186/s13104-020-05066-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160965PMC

Hemorrhoidal artery ligation with Doppler guidance vs digital guidance for grade II-III hemorrhoidal disease treatment: Study protocol clinical trial (SPIRIT Compliant).

Medicine (Baltimore) 2020 Apr;99(15):e19424

Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), Moscow, Russia.

Introduction: Hemorrhoidal artery ligation (HAL) with Doppler guidance and suture fixation of hemorrhoidal nodes (RAR) is a popular minimally invasive technique for hemorrhoidal disease (HD) treatment which uses an ultrasound probe to detect hemorrhoidal arteries for further ligation. We hypothesized that ultrasound guidance has no advantages over manual hemorrhoidal arteries detection for HD treatment.The aim is to compare the results of HAL-RAR procedure in patients with stage II-III HD with Doppler and manual HA detection. Read More

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http://dx.doi.org/10.1097/MD.0000000000019424DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7220052PMC

[Submucosal laser ablation of internal hemorrhoids].

Khirurgiia (Mosk) 2020 (3):89-96

A.N. Ryzhikh State Scientific Center of Coloproctology of the Ministry of Health of Russia, Moscow, Russia.

Objective: To analyze efficacy and safety of submucosal laser ablation of internal hemorrhoids (SLT).

Material And Methods: Systematic review included 10 articles published in electronic databases PubMed, Cochrane Library, Elibrary until January 2019. There were only full-text publications from prospective clinical trials devoted to submucosal laser ablation in the treatment of hemorrhoids. Read More

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http://dx.doi.org/10.17116/hirurgia202003189DOI Listing

Ultrasound-targeted microbubble destruction-mediated miR-767 inhibition suppresses tumor progression of non-small cell lung cancer.

Exp Ther Med 2020 May 12;19(5):3391-3397. Epub 2020 Mar 12.

Department of General Surgery, Zibo City Linzi District People's Hospital, Zibo, Shandong 255400, P.R. China.

MicroRNAs (miRNAs/miRs) have important roles in tumor progression in various human cancers. Ultrasound-targeted microbubble destruction (UTMD)-mediated gene transfection has been considered a useful tool for improving cancer treatment. The present study aimed to investigate the role of miR-767 in non-small cell lung cancer (NSCLC) and further analyze the effects of UTMD-mediated miR-767 inhibition on tumor progression. Read More

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http://dx.doi.org/10.3892/etm.2020.8602DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132231PMC

Comparison of the short-term outcomes of using DST and PPH staplers in the treatment of grade III and IV hemorrhoids.

Sci Rep 2020 Mar 23;10(1):5189. Epub 2020 Mar 23.

Division of colorectal surgery, Department of surgery, Taipei Medical University Shuang-Ho Hospital, Taipei City, Taiwan.

Stapled hemorrhoidopexy has a few advantages such as less postoperative pain and faster recovery compared with conventional hemorrhoidectomy. There are two major devices used for stapled hemorrhoidopexy, PPH stapler (Ethicon EndoSurgery) and DST stapler (Covidien). This study was conducted to investigate the postoperative outcomes among patients with grade III and IV hemorrhoids who underwent hemorrhoidopexy with either of these two devices. Read More

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http://dx.doi.org/10.1038/s41598-020-62141-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7089945PMC

Post Hemorrhoidectomy Pain Management: The Latest News.

Rev Recent Clin Trials 2020 Apr 6. Epub 2020 Apr 6.

Department of Colorectal Surgery, Pôle des Maladies de l'Appareil Digestif (PMAD), Beaujon Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), University Denis Diderot (Paris VII), 100 Boulevard du Général Leclerc, 92110, Clichy. France.

Anal post-operative pain is one of the principal issues of surgical treatment of hemorrhoids and remains a distressing problem, for patients and physicians. Recent studies had concluded that appropriate postoperative pain management lead to higher patient satisfaction, earlier mobilization, fewer drug complications, eliminated adverse events, faster recovery, and decreased health care cost. However, despite advances in pain medicine, postoperative pain control remains problematic and remains an important unresolved issue that causes expense and patient dissatisfaction. Read More

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http://dx.doi.org/10.2174/1574887115666200406122009DOI Listing

Management of Hemorrhoidal Disease in Special Conditions: A Word of Caution.

Rev Recent Clin Trials 2020 Apr 6. Epub 2020 Apr 6.

Department of Surgical Sciences, University of Turin, Città della Salute e della Scienza Hospital. Italy.

Background: Hemorrhoids are a common disease, that is often considered an easy problem to solve. Unfortunately, some particular clinical conditions, including Inflammatory Bowel Diseases (IBD), pregnancy, coagulophaties, immunosuppression, cirrhosis with portal hypertension, and proctitis after radiotherapy, challenge the hemorrhoids management and the outcomes.

Methods: Research and online contents related to hemorrhoids' treatment in special conditions is reviewed in order to help colorectal surgeons in daily practice. Read More

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http://dx.doi.org/10.2174/1574887115666200406121308DOI Listing