6,988 results match your criteria Hemorrhoids


The in vitro and in vivo antibacterial activities of uniflorous honey from a medical plant, Scrophularia ningpoensis Hemsl., and characterization of its chemical profile with UPLC-MS/MS.

J Ethnopharmacol 2022 Jun 22:115499. Epub 2022 Jun 22.

College of Animal Sciences (College of Bee Science), Fujian Agriculture and Forestry University, Fuzhou, 350002, China; College of Marine Sciences, Fujian Agriculture and Forestry University, Fuzhou, 350002, China. Electronic address:

Ethnopharmacological Relevance: According to the Compendium of Materia Medica, honey has been used as a traditional medicine in treatment against mucositis, tinea, hemorrhoids and psoriasis. In complementary medicine, due to its significant antimicrobial activity, honey has been widely used as a remedy for skin wounds and gastrohelcosis for thousands of years.

Aim Of The Study: This study is aimed at exploring the antimicrobial activity and mechanisms of honey sourced from medical plants, and revealing the composition-activity relationship, to facilitate their complementary and alternative application in the therapy of bacterial infectious diseases. Read More

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Efficacy and safety of micronized purified flavonoid fractions for the treatment of postoperative hemorrhoid complications: A systematic review and meta-analysis.

Phytomedicine 2022 Jun 17;104:154244. Epub 2022 Jun 17.

Inner Mongolia Medical University, Hohhot, Inner Mongolia 010110; Inner Mongolia Hospital of Traditional Chinese Medicine, Hohhot, Inner Mongolia 010020; Inner Mongolia Institute of Traditional Chinese and Mongolian Medicine, Hohhot, Inner Mongolia 010010; Baotou Medical College, Baotou, Inner Mongolia 014040. Electronic address:

Background: Hemorrhoids, a common anorectal disease, seriously affects patients' quality of life. Micronized purified flavonoid fractions (MPFF) have been shown to improve hemorrhoid symptoms.

Purpose: To evaluate the efficacy and safety of MPFF in treating postoperative hemorrhoid complications. Read More

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The necessity of preoperative enema preparation for hemorrhoidal surgery: a single-center comparative study.

Langenbecks Arch Surg 2022 Jun 21. Epub 2022 Jun 21.

Division of Colorectal Surgery, Department of Surgery, Shuang Ho Hospital, Taipei Medical University, Number 291, Zhongzheng Road, Zhonghe District, New Taipei City, 235, Taiwan.

Background: Hemorrhoidal surgery is a common treatment for high-grade hemorrhoids. The necessity of preoperative enema preparation (PEP) in hemorrhoidal surgery is inconclusive. This study aims to evaluate the benefit and safety of PEP in hemorrhoidal surgery. Read More

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Modified rubber band ligation for treatment of grade II/III hemorrhoids: clinical efficacy and safety evaluation-a retrospective study.

BMC Surg 2022 Jun 20;22(1):238. Epub 2022 Jun 20.

Department of General Sugury, Ningbo Medical Treatment Centre Li Huili Hospital, 1111 Jiangnan Road, Ningbo, 315000, People's Republic of China.

Background: Massive, delayed bleeding (DB) is the most common major complication of Rubber Band Ligation (RBL) for internal hemorrhoids caused by premature band slippage. In this study we modified conventional RBL to prevent early rubber band slippage and evaluated its clinical efficacy and safety.

Methods: Study participants were consecutive patients with grade II or III internal hemorrhoids treated with RBL at Ningbo Medical Center of Lihuili Hospital from January 2019 to December 2020. Read More

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Effectiveness of Mayinglong Musk Hemorrhoid Ointment on Wound Healing and Complications after Internal Hemorrhoid Ligation and External Hemorrhoidectomy.

Evid Based Complement Alternat Med 2022 9;2022:5630487. Epub 2022 Jun 9.

Department of Obstetrics and Gynecology, People's Liberation Army Navy 971 Hospital, Qingdao, Shandong, China.

Objective: To investigate the effect of Mayinglong Musk Hemorrhoids Ointment on wound healing and complications after internal hemorrhoid ligation and external hemorrhoidectomy.

Methods: This is a retrospective study. A total of 100 patients with mixed hemorrhoids who were treated in our hospital from August 2019 to October 2020 were recruited and assigned to an operation group ( = 50, internal hemorrhoid ligation, and external hemorrhoidectomy) or a combined group ( = 50, use of Mayinglong Musk Hemorrhoid Ointment after internal hemorrhoid ligation and external hemorrhoidectomy). Read More

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Infiltration of Bupivacaine and Triamcinolone in Surgical Wounds of Milligan-Morgan Hemorrhoidectomy for Postoperative Pain Control: A Double-Blind, Randomized, Controlled Clinical Trial.

Dis Colon Rectum 2021 Dec 13. Epub 2021 Dec 13.

Department of General Surgery, Vic Hospital Consortium, Spain.

Background: Pain management after hemorrhoidectomy continues to be challenging.

Objective: The aim of this study was to evaluate the effectiveness of infiltration of bupivacaine and triamcinolone in surgical wounds of Milligan-Morgan hemorrhoidectomy for postoperative pain relief.

Design: A controlled, randomized, double-blind clinical trial was conducted between May 2015 and June 2019. Read More

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December 2021

[Hemorrhoidal disease in 2022 : how to select the most appropriate treatment ?]

Rev Med Suisse 2022 Jun;18(786):1200-1204

Service de chirurgie viscérale, Département de chirurgie, Hôpitaux universitaires de Genève, 1211 Genève 14.

Hemorrhoidal disease is frequent and can lead to major alteration of quality of life. Conservative treatment, instrumental therapies and surgical approach play a complementary role in the management of hemorrhoidal disease. Understanding all techniques is mandatory to guide the patient and offer the best individualized treatment. Read More

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Neonatal Hemorrhoids: Getting to the Bottom of an Uncommon Finding.

J Pediatr Gastroenterol Nutr 2022 Jun 10. Epub 2022 Jun 10.

Department of Pediatrics, Walter Reed National Military Medical Center, Bethesda, MD.

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Be Kind to Your Behind: A Systematic Review of the Habitual Use of Bidets in Benign Perianal Disease.

Evid Based Complement Alternat Med 2022 31;2022:1633965. Epub 2022 May 31.

Department of Surgery, University of Saskatchewan, Saskatoon, Canada.

Background: Benign perianal disease carries significant morbidity and financial burden on the healthcare system. Given that sitz baths are recommended as a treatment modality, we considered whether using a continuous stream of water, in the form of a bidet, offers a convenient and effective alternative. Bidet use is the predominant form of perianal hygiene in Asia, but its role in perianal disease is unknown. Read More

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Chemico-Pharmacological Screening of the Methanol Extract of D.C. Deciphered Promising Antioxidant and Hepatoprotective Potentials: Evidenced from , , and Computer-Aided Studies.

Molecules 2022 May 27;27(11). Epub 2022 May 27.

Department of Pharmacy, Gono Bishwabidyalay, Dhaka 1344, Bangladesh.

D.C. (family: Asteraceae) has abundant uses in the alternative medicinal practice, and this species is commonly used in the treatment of diabetes, rheumatism, cuts or wounds, asthma, kidney stones, cough, urinary tract bleeding, gall bladder stones, hepatitis, diarrhea, hemorrhoids, constipation, vomiting, fertility problems, blood poisoning, septicemia, skin allergy, indigestion, high cholesterol levels, and so on. Read More

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Safety and Effectiveness of a New Electrical Detachable Microcoil for Embolization of Hemorrhoidal Disease, November 2020-December 2021: Results of a Prospective Study.

J Clin Med 2022 May 28;11(11). Epub 2022 May 28.

Grupo de Investigación en Técnicas Minimamente Invasivas (GITMI), University of Zaragoza, 500013 Zaragoza, Spain.

Purpose: The purpose of this study was to prospectively evaluate the efficacy and safety of a new, bare platinum, detachable microcoil as a metallic embolization agent in the treatment of hemorrhoidal disease.

Material And Methods: This prospective single-center study evaluated a new, bare platinum, electrical, detachable microcoil (Prestige plus coil (Balt Montmorency France)) for use in vascular embolization in patients with hemorrhoidal disease. Between January 2020 and January 2021, 24 embolization procedures were performed in 21 patients (12 males, 9 females; mean age 44. Read More

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Drug-Eluting Rubber Bands for Tissue Ligation.

ACS Appl Mater Interfaces 2022 Jun 7;14(24):27675-27685. Epub 2022 Jun 7.

Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, New York 10065, United States.

Rubber band ligation is a commonly used method for the removal of tissue abnormalities. Most often, rubber band ligation is performed to remove internal hemorrhoids unresponsive to first line treatments to avoid surgery. While the procedure is considered safe, patients experience mild to significant pain and discomfort until the tissue sloughs off. Read More

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Cytochrome P450 inhibition activities of non-standardized botanical products.

J Ethnopharmacol 2022 Jun 2:115406. Epub 2022 Jun 2.

School of Pharmaceutical Sciences, Universiti Sains Malaysia, 11800, Pulau Pinang, Malaysia. Electronic address:

Ethnopharmacological Relevance: R-tab, H-tab and E-cap botanical products are used for the treatment of various ailments. R-tab is traditionally prescribed for improving urination, H-tab is for relieving piles, hemorrhoids, fissures, and rectal inflammation and E-cap is for regulating menstruation.

Aims Of The Study: To extract the botanical products and determine their potential interaction with the cytochrome P450 (CYP1A2, CYP2D6 and CYP3A4) enzymes. Read More

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The Utility of Submucosal Linear Enhancement on Dynamic Computed Tomography for Patients With Internal Hemorrhoids.

J Comput Assist Tomogr 2022 May 20. Epub 2022 May 20.

From the Departments of Radiology.

Objective: The purpose of this study was to evaluate the utility of submucosal linear enhancement on dynamic computed tomography (CT) for patients with internal hemorrhoids.

Methods: We retrospectively reviewed patients who were admitted to our institution due to acute lower gastrointestinal bleeding and underwent both dynamic CT and colonoscopy. The presence of submucosal linear enhancement of the intestinal wall from the lower rectum to the anal canal was evaluated using arterial-phase CT images. Read More

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Tamponade dressing versus no dressing after haemorrhoidectomy: multicentre, randomized clinical trial.

BJS Open 2022 05;6(3)

Helios Klinikum Wuppertal, Department of Surgery II, University of Witten/Herdecke, Wuppertal, Germany.

Background: Symptomatic haemorrhoids are a common anorectal disorder. The aim of the study was to investigate whether the omission of tamponade dressings after haemorrhoidectomy reduces postoperative pain without increasing the risk of severe bleeding.

Method: This was an open-label, randomized clinical trial conducted at 14 German hospitals. Read More

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Corydalis saxicola Bunting Total Alkaloids ameliorate diet-induced non-alcoholic steatohepatitis by regulating hepatic PI3K/Akt and TLR4/NF-κB pathways in mice.

Biomed Pharmacother 2022 Jul 25;151:113132. Epub 2022 May 25.

Department of Pharmacology of Chinese Materia Medica, China Pharmaceutical University, 639 Longmian avenue, Nanjing, PR China. Electronic address:

Corydalis saxicola Bunting (Yanhuanglian), distributed in Southwest China, is mainly used for treatment of hepatitis, oral mucosal erosion, conjunctivitis, dysentery, acute abdominal pain and hemorrhoids in the folk. Corydalis saxicola Bunting Total Alkaloids (CSBTA) are the active ingredients extracted from the root of C. saxicola bunting. Read More

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Avoidance of Compulsive Defecation and Tone Are Effective to Decrease Recurrence after Outpatient Procedures for Advanced Hemorrhoids.

Authors:
Pankaj Garg

Dis Colon Rectum 2022 May 25. Epub 2022 May 25.

Chief Colorectal Surgeon Indus International Hospital Mohali, Punjab, India.

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Comprehensive literature review of the applications of surgical laser in benign anal conditions.

Lasers Med Sci 2022 May 23. Epub 2022 May 23.

General Surgery Department, Colorectal Surgery Unit, Mansoura University Hospitals, Mansoura University, 60 El-Gomhoria Street, Mansoura, 35516, Dakahlia, Egypt.

Surgery for benign anal conditions is a common practice and is usually followed by a good outcome. The present review aimed to summarize the emergence and evolution of different laser techniques used for the treatment of benign anal conditions and report their current outcome. PubMed and Scopus were searched for studies that assessed the use of laser in benign anal conditions. Read More

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Management and Treatment of External Hemorrhoidal Thrombosis.

Front Surg 2022 3;9:898850. Epub 2022 May 3.

Department of Medicine, Surgery and Neurosciences, Unit of General Surgery and Surgical Oncology, University of Siena, Siena, Italy.

Background: External hemorrhoidal thrombosis (EHT) is a common complication of hemorrhoidal disease. This condition causes extreme pain, likely resulting from internal anal sphincter hypertonicity, which traps the hemorrhoids below the dentate line thus leading to congestion and swelling. The choice of treatment remains controversial and both conservative and surgical options have been proposed in the last decades. Read More

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Laser hemorrhoidoplasty in the treatment of symptomatic hemorrhoids: a pilot Australian study.

Ann Coloproctol 2022 May 19. Epub 2022 May 19.

Department of Surgery, Epworth Healthcare, Melbourne, VIC, Australia.

Purpose: Traditional therapeutic approaches to the surgical management of hemorrhoid disease such as hemorrhoidectomies are plagued with severe postoperative pain and protracted recovery. Our pilot study aims to the laser hemorrhoidoplasty (LH) patients with symptomatic hemorrhoid disease that have failed conservative management for the first time in an Australian population.

Methods: Thirty patients were prospectively enrolled to undergo LH. Read More

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Simple mucopexy and hemorrhoidal arterial ligation with and without Doppler guide: a randomized clinical trial for short-term outcome.

Ann Coloproctol 2022 May 16. Epub 2022 May 16.

Colorectal Research Center, Iran University of Medical Sciences, Tehran, Iran.

Purpose: Hemorrhoids are the most common benign anorectal diseases. Mucopexy strengthens the anal canal mucosa, which can be performed alone or in combination with Doppler-guided (DG) hemorrhoidal artery ligation (HAL). In this study, we compared the postoperative complications between simple mucopexy plus HAL with and without a Doppler guide. Read More

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Modified ligation procedure for prolapsed haemorrhoids versus stapled haemorrhoidectomy for the management of symptomatic haemorrhoids (MoLish): randomized clinical trial.

BJS Open 2022 05;6(3)

Departments of Anorectal Surgery, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, P.R. China.

Background: The aim of this study was to compare a modified ligation procedure versus stapled haemorrhoidectomy (SH) in patients with symptomatic haemorrhoids.

Methods: This randomized trial included patients with symptomatic haemorrhoids treated in Shanghai from May 2018 to September 2021. Eligible patients were randomly 1:1 assigned the modified ligation procedure for prolapsed haemorrhoids (MLPPH) and SH groups. Read More

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Clinical Outcomes Following Rectal Artery Embolisation for the Treatment of Internal Haemorrhoids: A Systematic Review and Meta-Analysis.

Cardiovasc Intervent Radiol 2022 May 12. Epub 2022 May 12.

Department of Interventional Radiology, Monash Health, Clayton, VIC, 3168, Australia.

Objectives: Haemorrhoidal disease (HD) is a common anorectal disorder which can substantially impair quality of life. Rectal artery embolisation (RAE) is a recently described technique for the management of HD, however, its clinical efficacy and safety are unclear at present. The objective of this systematic review and meta-analysis is to evaluate the clinical outcomes following RAE. Read More

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Editorial: Haemorrhoidal Disease: Old Solutions and Future Perspectives.

Front Surg 2022 12;9:905570. Epub 2022 Apr 12.

Department of Surgery, School of Nutrition and Translational Research in Metabolism (NUTRIM), Maastricht University, Maastricht, Netherlands.

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Indications, Feasibility, and Safety of TST STARR Plus Stapler for Degree III Hemorrhoids: A Retrospective Study of 125 Hemorrhoids Patients.

Front Surg 2022 13;9:860150. Epub 2022 Apr 13.

Department of Anorectal Surgery, Changshu Hospital Affiliated to Nanjing University of Chinese Medicine, Changshu, China.

Background: Stapler hemorrhoidopexy (SH) has been widely accepted for hemorrhoids patients because of its low postoperative pain, but it is also associated with a high recurrence rate. The recurrence might be due to failure to completely remove the prolapsed tissue or insufficient removal capacity of the instruments. Removing more prolapsed tissue to reduce the recurrence is believed to benefit more severe prolapsed hemorrhoids patients. Read More

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Preliminary Results of the First 50 Patients Undergoing Sclerotherapy for II-Degree Hemorrhoidal Disease Using an Automated Device.

Front Surg 2022 14;9:882030. Epub 2022 Apr 14.

Unit of General Surgery and Surgical Oncology, Department of Medicine, Surgery, and Neurosciences, University of Siena, Siena, Italy.

Background: Sclerotherapy is defined as the injection of sclerosant agents causing fibrosis and scarring of the surrounding tissue. It is currently employed for the treatment of I-III degree hemorrhoidal disease (HD). The aim of this study is to investigate the use of a new automated device for the injection of 3% polidocanol foam. Read More

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Preventing hemorrhoids during pregnancy: a multicenter, randomized clinical trial.

BMC Pregnancy Childbirth 2022 Apr 30;22(1):374. Epub 2022 Apr 30.

Clinic of Obstetrics and Gynecology, Faculty of Medicine, Vilnius University, Vilnius, Lithuania.

Background: To compare specific dietary and behavioral recommendations for hemorrhoids prevention during pregnancy.

Methods: This was a randomized, single-blind, multicenter trial conducted in three different clinical centers. Patients were randomly allocated into two groups in a ratio of 1:1. Read More

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Intestinal Haemorrhage and Colitis Induced by Treatment With Osimertinib for Non-Small-Cell Lung Carcinoma: A Case Report.

Front Pharmacol 2022 5;13:854277. Epub 2022 Apr 5.

Department of Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.

Osimertinib is recommended either as the first-line therapy for sensitizing EGFR-mutations (FLAURA trial) or at progression to first-/second-generation EGFR inhibitors in the presence of resistance mutation T790M (AURA 3 study). It can effectively improve the prognosis of patients with NSCLC with manageable adverse reactions. Among adverse events, intestinal haemorrhage is rare and requires extensive study on its potential lethality. Read More

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Sclerotherapy in Hemorrhoids.

Indian J Surg 2022 Apr 20:1-5. Epub 2022 Apr 20.

Department of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China.

Injection sclerotherapy for all grades of interhemorrhoids in various situations and co-morbidities has become popular method of treatment. Several types of surgical operations both conventional and stapled hemorrhoidectomy has many and serious described side effects. On the contrary, proctoscopic injection sclerotherapy using some of the modern sclerosants and thin bore needle injections is an office-based ambulatory method of treatment of internal hemorrhoids; it is low in cost, devoid of any major complications besides it is quite successful as reported. Read More

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