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Am J Ophthalmol Case Rep 2020 Sep 18;19:100743. Epub 2020 May 18.

King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.

Purpose: To provide clinical and pathological features of posterior persistent fetal vasculature (PFV) presenting with vitreous hemorrhage.

Observations: Case 1 was a one-year old male with PFV reaching up to the posterior lens capsule. Case 2 and 3 both had history of blunt trauma. Read More

Am J Ophthalmol Case Rep 2020 Sep 1;19:100709. Epub 2020 May 1.

Bascom Palmer Eye Institute, Miami, FL, USA.

Purpose: to present the now vitrectomy technique through a limbus via preexisting holes in the Eckardt TKP.

Methods: the surgical technique performed in a case of four-year-old girl presented with a complete hyphema and vitreous hemorrhage in the left eye.

Results: the vitrectomy was performed vial a limbal approach from the TKP without making additional sclerotomies. Read More

Acta Diabetol 2020 May 29. Epub 2020 May 29.

2nd Department of Ophthalmology, National and Kapodistrian University of Athens, Athens, Greece.

Aims: To compare intravitreal ranibizumab as monotherapy or in combination with panretinal photocoagulation (PRP) in patients with proliferative diabetic retinopathy (PDR) and coexistent diabetic macular edema (DME) in a long-term follow-up of 24 months.

Methods: Participants in this prospective study were 47 patients with PDR and concurrent DME, who were randomized at baseline into two groups: (i) the "ranibizumab alone" group (n = 23), which was treated with at least 3 intravitreal ranibizumab injections as a loading phase, and (ii) the "combination" group (n = 24), which was treated with PRP and at least 3 intravitreal ranibizumab injections. Thereafter, all patients were followed up at a pro re nata (PRN) basis, with regular monthly monitoring for 24 months. Read More

Ocul Immunol Inflamm 2020 May 28:1-6. Epub 2020 May 28.

Department of Ophthalmology, Northwestern University Feinberg School of Medicine , Chicago, Illinois, USA.

Purpose: To describe clinical manifestations of patients with tubulointerstitial nephritis and uveitis syndrome (TINU) with a focus on posterior segment findings.

Methods: Retrospective chart review.

Results: 17 patients were diagnosed with TINU. Read More

Indian J Ophthalmol 2020 Jun;68(6):1188-1191

Disha Eye Hospitals, Kolkata, West Bengal, India.

We describe the successful use of the B-HEX pupil expansion device in four cases of combined phacovitrectomy with significant cataract, non-dilating pupil, and surgical vitreoretinal pathologies including vitreous hemorrhage, inferior retinal detachment (RD) with proliferative vitreoretinopathy in an oil filled eye, recurrent rhegmatogenous RD, and macular hole with RD localized to the posterior pole in an eye with uveitic sequelae. The B-HEX remained well engaged and maintained excellent mydriasis throughout the surgery despite wide fluctuations in intraocular pressure and anterior chamber fluidics. This is the first series describing use of B-HEX for combined phacovitrectomy due to myriad causes. Read More

Indian J Ophthalmol 2020 Jun;68(6):988-993

Dr. Rajendra Prasad Centre for Ophthalmic Sciences, AIIMS, New Delhi, India.

The present review describes the posterior segment complications following surgical management of glaucoma. Although the majority of glaucoma cases are managed medically, still a large number of patients may require surgery. Moreover, with the advent of newer surgical techniques and adjuncts, encountering retinal complications post-surgery is not uncommon. Read More

Ann Palliat Med 2020 May 8. Epub 2020 May 8.

Department of Ophthalmology, Liuzhou Hospital of Traditional Chinese Medicine, Liuzhou 545006, China.

Background: During the remove of oil from the silicone oil-filled eye after vitrectomy, perfusion fluid is often mistakenly aspirated when mechanical force is used to remove the oil. This leads to a sudden sharp drop in intraocular pressure and collapse of the eyeball, which may cause complications. The aspiration of perfusion fluid can be detected when the oil is removed manually, and the force of the hand and location of the aspiration can be adjusted to remove the silicone oil instead. Read More

Ophthalmol Retina 2020 Mar 18. Epub 2020 Mar 18.

Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania. Electronic address:

Purpose: To describe the clinical and imaging characteristics, pathologic features, and management options of retinal pigment epithelium (RPE) adenoma/adenocarcinoma.

Design: Retrospective case series.

Participants: Fifty-one patients with RPE adenoma/adenocarcinoma. Read More

J Clin Med 2020 May 13;9(5). Epub 2020 May 13.

Department of Ophthalmology, Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea. #327 Sosa-ro, Wonmi-gu, Bucheon, Gyeonggi-do 14647, Korea.

Purpose: To investigate the relationships among the retinal nonperfusion (NP) area, neovascularization (NV) area, and aqueous humor vascular endothelial growth factor (VEGF) levels in quiescent proliferative diabetic retinopathy (PDR).

Methods: Forty-seven eyes from 47 patients with treatment-naïve PDR that did not show macular edema or vitreous hemorrhage were enrolled. NP area, NV number, and NV area were quantitatively measured using ultra-widefield fluorescein angiography in an automated manner. Read More

Graefes Arch Clin Exp Ophthalmol 2020 May 14. Epub 2020 May 14.

Asociados de Macula, Vitreo y Retina de Costa Rica, Primer Piso Torre Mercedes Paseo Colon, San Jose, Costa Rica.

Purpose: To report our experience in non-contact wide-angled visualization with chandelier-assisted scleral buckling (SB) in uncomplicated primary rhegmatogenous retinal detachments (RRD).

Methods: Retrospective case series of 282 eyes that underwent non-contact wide-angled visualization with chandelier-assisted SB and were followed for a mean of 13.5 months. Read More

Appl Opt 2020 Apr;59(12):3614-3618

In this work we study fundus reflection in the case of retinal detachment. Vitreous humor builds up beneath the retina through a break in the retina or when there is traction on the retina. Further, we assume that this detachment is associated with hemorrhage in regions both above and below the retina. Read More

J Glaucoma 2020 May 8. Epub 2020 May 8.

Department of Ophthalmology, University of North Carolina-Chapel Hill, Chapel Hill.

Choroidal hemorrhages involve bleeding into the potential space between the choroid and sclera and are a serious ocular complication. Common causes of choroidal hemorrhages include intraocular surgeries, such as scleral buckling, cataract extractions, and glaucoma filtering procedures, or trauma. We report a case of choroidal and vitreous hemorrhage after micropulse cyclophotocoagulation. Read More

Ophthalmologe 2020 May 8. Epub 2020 May 8.

Campus Kiel, Klinik für Augenheilkunde, Universitätsklinikum Schleswig-Holstein, Kiel, Deutschland.

In the case of acute vitreous body hemorrhage, the ophthalmologist is faced with the question of whether spontaneous absorption can be awaited or whether a vitrectomy is necessary. In addition to the intensity of the bleeding, the underlying cause also plays an important role. A thorough medical history is therefore important. Read More

Medicine (Baltimore) 2020 May;99(19):e20189

Department of Endocrinology, The First Affiliated Hospital of Chongqing Medical University, Chongqing.

We aim to explore the relationship between early-onset diabetes and proliferative diabetic retinopathy (PDR) in type 2 diabetes mellitus (T2DM) patients with microalbuminuria.A total of 461 T2DM patients with microalbuminuria were enrolled. Subjects were defined as early-onset or late-onset based on the age at which they were diagnosed with diabetes (<40 and ≥40 years, respectively). Read More

Medicine (Baltimore) 2020 May;99(19):e20086

Department of Ophthalmology, China-Japan Friendship Hospital, Beijing, China.

Background: Vitreous hemorrhage (VH) is a common ophthalmic disease with a high rate of blindness, which will seriously affect the quality of life of patients and bring great burden to patients' families and society. The treatment for VH contains medical therapy, lasers, and surgery. At present, there is no recognized western medicine with definite curative effect and little side effect for the treatment of VH. Read More

Br J Ophthalmol 2020 May 6. Epub 2020 May 6.

Retina Department, Vitreous Retina Macula Consultants of New York, New York, New York, USA.

Background: To describe the clinical presentation and characteristic imaging features of deep retinal haemorrhages primarily located in the Henle fibre layer (HFL) of the macula. The spectrum of aetiologies and a comprehensive theory of pathogenesis are presented.

Methods: This is a retrospective, multicentre case series evaluating eyes with retinal haemorrhage in HFL. Read More

BMC Ophthalmol 2020 May 6;20(1):185. Epub 2020 May 6.

Department of Ophthalmology, Tianjin Medical University General Hospital, No. 154, Anshan Road, Tianjin, 300052, China.

Background: To document characteristics and treatments of ocular blast injury from a fire and explosion.

Method: Authors retrospectively evaluated 116 patients with 166 eye injuries from six hospitals. Terminology of ocular injury referred to Birmingham Eye Trauma Terminology, and best-corrected visual acuity (BCVA) was categorized with the ocular trauma score (OTS) grading system. Read More

Am J Ophthalmol Case Rep 2020 Jun 23;18:100719. Epub 2020 Apr 23.

L&T Ophthalmic Pathology Department, Sankara Nethralaya, 18 College Road, Chennai, 600006, Tamilnadu, India.

Turk J Ophthalmol 2020 Apr;50(2):115-122

Celal Bayar University Faculty of Medicine, Department of Ophthalmology, Manisa, Turkey.

We present patient characteristics and follow-up results of cases with anterior chamber dexamethasone implant migration. The common feature of all six presented cases was vitrectomized eyes. Four of the patients had sutured intraocular lens (IOL) implantation due to complicated cataract surgery, one had combined retinal detachment surgery with sutured IOL implantation, and one had vitrectomy for diabetic intravitreal hemorrhage cleaning and uncomplicated cataract surgery. Read More

J Cataract Refract Surg 2020 May;46(5):797

A now-17-year-old girl was reportedly born with no pupil formed in her right eye. In her first week of life, she underwent attempted pupilloplasty at a foreign institution. Surgery was reported to have been complicated and followed by vitreous hemorrhage. Read More

J Cataract Refract Surg 2020 May;46(5):716-720

From the Department of Translational Surgery and Medicine, Ophthalmology, University of Florence, Careggi, Florence, Italy.

Purpose: To assess the surgical and refractive outcomes of a new technique of sutureless scleral fixation (SSF) using a single-piece foldable acrylic intraocular lens (IOL) (Carlevale).

Setting: Department of Translational Surgery and Medicine, Ophthalmology, University of Florence, Careggi, Florence, Italy.

Design: Prospective observational case series. Read More

JAMA Ophthalmol 2020 Apr 30. Epub 2020 Apr 30.

W. K. Kellogg Eye Center, Department of Ophthalmology and Visual Sciences, University of Michigan Medical School, Ann Arbor.

Importance: Quantification of nonperfusion (NP) and neovascularization (NV) in diabetic retinopathy (DR) may identify better biomarkers of disease progression.

Objective: To identify demographic risk factors and markers of advanced DR that are associated with increased areas of NP and NV in eyes with disease ranging from no DR but diagnosed as having diabetes to proliferative DR (PDR) and to calculate a threshold total area of NP that may be associated with an increased risk of PDR.

Design, Setting, And Participants: This retrospective case series was performed on ultrawidefield fluorescein angiography (UWF FA) images from January 2009 to May 2018 at the University of Michigan Kellogg Eye Center. Read More

Retina 2020 Apr 28. Epub 2020 Apr 28.

Department of VitreoRetina, Shri Bhagwan Mahavir Vitreoretinal Services, Medical Research Foundation, Sankara Nethralaya, Chennai, India.

Purpose: To report anatomical and visual outcomes and potential prognostic factors with microincision vitrectomy surgery in Stage 5 retinopathy of prematurity.

Methods: The medical records of premature babies who underwent microincision vitrectomy surgery for Stage 5 retinopathy of prematurity using 23G, 25G, or 27G instrumentation and had a minimum follow-up of 6 weeks were, retrospectively, analyzed. Primary outcome measures were anatomical success at last follow-up defined as retinal attachment at the posterior pole and visual outcomes. Read More

J Cataract Refract Surg 2020 Jan 21. Epub 2020 Jan 21.

Department of Translational Surgery and Medicine, Ophthalmology, University of Florence, Careggi, Florence, Italy.

Purpose: To assess the surgical and refractive outcomes of a new technique of sutureless scleral fixation (SSF) using a single-piece foldable acrylic Carlevale lens (Soleko) SETTING: Department of Translational Surgery and Medicine, Ophthalmology, University of Florence, Careggi, Florence, Italy DESIGN: Prospective observational case series METHODS: Thirty-two eyes of 32 patients with aphakia, dislocated IOL or subluxated lens who underwent sutureless scleral fixation (SSF) of a mono-piece hydrophobic acrylic Carlevale lens were studied. The patients' data including pre-operative and post-operative refractive status, complications during and after surgery were recorded. The intraocular lens tilt was evaluated using anterior segment (AS)- OCT. Read More

Retina 2020 Apr 17. Epub 2020 Apr 17.

Department of Surgery, Division of Ophthalmology, Kobe University Graduate School of Medicine, Kobe, Japan.

Purpose: To show the usefulness of the intraoperative three-dimensional fluorescein angiography (3D-FA)-guided pars plana vitrectomy.

Methods: The NGENUITY 3D visualization system was used for the digital assisted vitrectomy. Three-dimensional fluorescein angiography-guided pars plana vitrectomy was performed in three patients with vitreous hemorrhage secondary to proliferative diabetic retinopathy. Read More

Int Ophthalmol 2020 Apr 27. Epub 2020 Apr 27.

Department of Ophthalmology, Huashan Hospital, Fudan University, No. 12 Middle Urumqi Road, Shanghai, 200040, China.

Purpose: To evaluate the safety of phacoemulsification cataract surgery in the patients undergoing dual antiplatelet therapy with aspirin and clopidogrel.

Methods: Consecutive patients undergoing phacoemulsification cataract surgery with a clear corneal incision under topical anesthesia were eligible for inclusion in the study. Thirty-eight eyes from 38 patients on combined aspirin and clopidogrel therapy who continued the treatment were classified into the maintenance group, a matched group of 38 eyes from 38 patients on no antiplatelet/anticoagulant therapy as the control group. Read More

BMC Ophthalmol 2020 Apr 22;20(1):164. Epub 2020 Apr 22.

Department of Organ of Sense, Sapienza University of Rome, Viale del Policlinico, 155 00161, Rome, Italy.

Background: Intraorbital metallic foreign bodies have varied clinical presentations. Here, we report the unusual case of intraoperative evidence of spontaneously healed posterior scleral perforation in a severe ballistic trauma without previous instrumental signs of penetrating wound and complete visual restoration after surgery.

Case Presentation: The patient was hit by several lead hunting pellets in the chest, abdomen, limbs, face and orbit. Read More

Int J Retina Vitreous 2020 16;6:10. Epub 2020 Apr 16.

1Department of Ophthalmology, Hôpital Maisonneuve-Rosemont, Université de Montréal, 5415 Assumption Blvd, Montréal, QC H1T 2M4 Canada.

Background: Multiple surgical techniques exist for the repair of rhegmatogenous retinal detachments (RRD). Suprachoroidal buckling (SCB), consisting of injecting viscoelastic material in the suprachoroidal space to allow chorioretinal apposition, has been recently described in the repair of RRD. The aim of this study is to report the complications of SCB and to propose measures to decrease their incidence during the learning curve. Read More

Ophthalmology 2020 Mar 9. Epub 2020 Mar 9.

Mid-Atlantic Retina, Philadelphia, Pennsylvania.

Purpose: Anatomically similar rhegmatogenous retinal detachments (RRDs) can be treated with scleral buckle (SB), pars plana vitrectomy (PPV), or SB combined with PPV (PPV/SB). This study compares moderately complex phakic primary RRD treated with SB, PPV, or PPV/SB to review anatomic and visual outcomes.

Design: Multicenter, retrospective, interventional cohort study. Read More

Prog Retin Eye Res 2020 Apr 18:100862. Epub 2020 Apr 18.

Department of Ophthalmology, Federal University of São Paulo, Rua Botucatu, 806, São Paulo, SP, Brazil; Department of Ophthalmology, SSM Health Saint Louis University Hospital, Saint Louis University, 1755, S. Grand Boulevard, Saint Louis, MO, USA.

Intravitreal injections have become the most commonly performed intraocular treatments worldwide. Because intravitreal injections may induce severe adverse events, such as infectious and noninfectious endophthalmitis, cataract, ocular hypertension, vitreous hemorrhage, or retinal detachment, appropriate awareness of the materials and techniques used are essential to reduce these sight-threatening complications. This review provides insights into the needles, syringes, silicone oil coating, sterilization methods, devices to assist intravitreal injections, scleral piercing techniques using needles, syringe handling, anesthesia, and safety issues related to materials and techniques. Read More

BMC Ophthalmol 2020 Apr 19;20(1):156. Epub 2020 Apr 19.

Department of Ophthalmology, West China Hospital, Sichuan University, No. 37 Guoxue Lane, Chengdu, 610041, Sichuan, China.

Background: To evaluate the etiology, demographic profile, clinical features, and outcomes in patients with peripapillary subretinal hemorrhage (PSH).

Methods: Thirty-eight eyes of 37 consecutive patients with PSH were enrolled in this prospective observational study over 4 years; all were followed for 2 years. The main outcome measures were demographic profile, possible etiology, clinical features, outcome, and prognosis. Read More

Eur J Ophthalmol 2020 Apr 20:1120672120916722. Epub 2020 Apr 20.

Department of Clinical Sciences and Community Health, Eye Clinic San Giuseppe Hospital, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Multimedica, University of Milan, Milan, Italy.

Purpose: To describe the unusual presentation, diagnosis, and clinical course of an early-onset X-linked infantile retinoschisis.

Case Report: A 6-month-old infant presented with strabismus and poor fixation. After the detection of bilateral intraretinal hemorrhage and diffuse dystrophic retinal pattern at indirect ophthalmoscopy, the patient received a complete evaluation under anesthesia. Read More

Zhonghua Yan Ke Za Zhi 2020 Apr;56(4):272-278

Department of Ophthalmology, Peking University People's Hospital, Eye diseases and optometry institute, Beijing Key Laboratory of Diagnosis and Therapy of Retinal and Choroid Diseases, College of Optometry, Peking University Health Science Center, Beijing 100044, China.

To evaluate the treatment of vasoproliferative tumors of the retina (VPTR). Retrospective case series study. The clinical data of 20 VPTR patients (20 eyes) were retrospectively analyzed, including 2 eyes only treated by cryotherapy, 1 eye only treated by photocoagulation and 1 eye only treated by ruthenium-106 brachytherapy. Read More

BMC Ophthalmol 2020 Mar 23;20(1):117. Epub 2020 Mar 23.

Department of Ophthalmology, China Medical University Hospital, China Medical University, 2 Yuh-Der Road, Taichung City, 40447, Taiwan.

Background: A cyclodialysis cleft often leads to direct communication between the anterior chamber and the suprachoroidal space. It is a rare condition that is encountered with blunt trauma, and less commonly, after surgery. Hypotony is the major sequelae that may lead to hypotonous maculopathy, optic disc edema, corneal folds, and astigmatism. Read More

Retina 2020 Apr 7. Epub 2020 Apr 7.

Save Sight Institute, University of Sydney, Sydney, NSW, Australia.

Purpose: There is renewed interest in subretinal drug delivery as the result of novel and emerging treatments for retinal diseases, including retinal gene therapy. However, our knowledge of the distribution of subretinally delivered drugs is incomplete; herein, we describe a qualitative and quantitative means of surveying the early intraocular distribution of subretinally delivered drugs using dilute sodium fluorescein (NaFl).

Methods: Sodium fluorescein 10% was serially diluted and mixed with a solution containing tissue plasminogen activator (tPA) at a final concentration of 0. Read More

Am J Ophthalmol Case Rep 2020 Jun 2;18:100687. Epub 2020 Apr 2.

Spencer Center for Vision Research, Byers Eye Institute, Stanford University, Palo Alto, CA, USA.

Purpose: To describe a case of unilateral retinal arteriolar occlusion following multiple intravitreal brolucizumab injections for neovascular age-related macular degeneration (nAMD).

Observations: A 92-year-old Caucasian woman presented with blurry vision in her left eye (OS) after receiving the third dose of intravitreal brolucizumab. At the time of presentation, visual acuity (VA) was 20/40 in her right eye (OD) and had decreased from 20/150 to count finger (CF) at 1-foot OS. Read More

GMS Ophthalmol Cases 2020 18;10:Doc13. Epub 2020 Mar 18.

Department of Ophthalmology, Fujita Health University Bantane Hospital, Aichi, Japan.

To report a case of unintentional retina artery amputation during macular peeling. Observational case report A 73-year-old female underwent surgery to treat epiretinal membrane (ERM) associated with severe staphyloma in her left eye. While the ERM/posterior hyaloid membrane visually enhanced with triamcinolone (TA) was peeled, a movement of the forceps unintentionally involved the inferior temporal branch artery near the inner edge of the staphyloma. Read More

PLoS One 2020 8;15(4):e0230713. Epub 2020 Apr 8.

Fondation Ophtalmologique A. De Rothschild, Paris, France.

Purpose: To evaluate the surgical technique for subretinal implantation of two sizes of PRIMA photovoltaic wireless microchip in two animal models, and refine these surgical procedures for human trials.

Methods: Cats and Macaca fascicularis primates with healthy retina underwent vitrectomy surgery and were implanted with subretinal wireless photovoltaic microchip at the macula/central retina. The 1. Read More

Ocul Oncol Pathol 2020 Mar 3;6(2):115-122. Epub 2019 Sep 3.

Department of Ophthalmology, University Vita-Salute, IRCCS San Raffaele, Milan, Italy.

Introduction: Gamma knife radiosurgery (GKR) has shown promising results in the treatment of intraocular uveal melanoma (UM) in terms of local tumor control. However, GKR is not free from potentially sight-threatening side effects, including cataract, dry eye disease, vitreous hemorrhage, radiation retinopathy (RR), radiation maculopathy (RM), optic neuropathy, and neovascular glaucoma. The aim of this paper is to report our 20-year experience in UM management with GKR focusing on the rate of clinical treatment-induced complications. Read More

BMC Ophthalmol 2020 Apr 6;20(1):130. Epub 2020 Apr 6.

Affiliated as vitreoretinal consultant, Hadi hospital, Jabriya, Kuwait.

Background: To compare efficacy and safety of intravitreal aflibercept (IVA) injection with panretinal photocoagulation (PRP) versus early vitrectomy for diabetic vitreous hemorrhage (VH).

Methods: Prospective, randomized study that included 34 eyes with diabetic VH. They were divided into two groups, Group Ι (17 eyes) received three successive IVA injections followed by PRP and group ΙΙ (17 eyes) for whom early vitrectomy was done. Read More

Curr Opin Ophthalmol 2020 May;31(3):185-191

Alcon Research, Ltd, Irvine, California, USA.

Purpose Of Review: To compare outcomes of 27-gauge and 23-gauge pars plana vitrectomy (PPV) for treatment of vitreoretinal diseases.

Recent Findings: Sixty-eight patients undergoing microincisional PPV for treatment of vitreoretinal diseases were randomized 1 : 1 to 27-gauge or 23-gauge surgery with a 7500 cuts-per-minute vitrectomy probe. The most common reasons for vitrectomy were epiretinal membrane (49%) and vitreous hemorrhage (24%). Read More

Am J Ophthalmol Case Rep 2020 Jun 12;18:100664. Epub 2020 Mar 12.

Division of Epidemiology and Clinical Applications, National Eye Institute, National Institutes of Health, Bethesda, MD, USA.

Purpose: To report the clinical course of two cases with Purtscher-like retinopathy (PLR), associated with peritoneal dialysis (PD), demonstrating disease recurrence and progression to neovascularization and vitreous hemorrhage.

Observations: Case 1 (45-year old woman) experienced acute bilateral vision loss. Medical history included hypertension, end-stage renal failure (ESRF), PD, and obstructive sleep apnea. Read More

J Ocul Pharmacol Ther 2020 Mar 18. Epub 2020 Mar 18.

Department of Ophthalmology, Ruijin Hospital Affiliated Shanghai Jiaotong University School of Medicine, Shanghai, China.

To assess the clinical effects of preoperative, intraoperative, or preoperative combined with intraoperative intravitreal conbercept (IVC) injection in vitrectomy with silicone oil tamponade for severe proliferative diabetic retinopathy (PDR). Ninety-eight eyes of 98 severe PDR patients undergoing vitrectomy with silicone oil tamponade were randomly assigned to 3 groups: Group 1 (34 eyes) received IVC injections 3 to 5 days before surgery; Group 2 (35 eyes) received IVC injections at the end of surgery; and Group 3 (29 eyes) received IVC injections 3 to 5 days before and at the end of operation. Follow-up examinations were performed for 6 months. Read More

J Evid Based Med 2020 May 13;13(2):116-124. Epub 2020 Mar 13.

Faculty of Medicine, Universitas Kristen Krida Wacana, West Jakarta, Indonesia.

Objectives: To evaluate the latest evidence concerning the efficacy of conbercept on vitrectomy for proliferative diabetic retinopathy (PDR) and its efficacy compared to control and other antivascular endothelial growth factor.

Methods: We performed a systematic literature search on topics that assess the role of conbercept in patients undergoing vitrectomy for PDR from inception to November 2019, using PubMed, EuropePMC, Cochrane Central Database, ProQuest, ScienceDirect, and Clinicaltrials.gov. Read More

Am J Ophthalmol Case Rep 2020 Jun 29;18:100642. Epub 2020 Feb 29.

Department of Ophthalmology, Meir Medical Center, Kfar Saba, Israel.

Purpose: Posterior pole retinal tears occur rarely following blunt trauma. We describe a case of traumatic macular tears, without concurrent peripheral retinal tears or holes.

Observations: A 17-year-old patient presented to our emergency unit with blunt ocular trauma and multiple maxillofacial fractures after being assaulted. Read More

Am J Ophthalmol Case Rep 2020 Jun 11;18:100609. Epub 2020 Feb 11.

Eye Center, Albert-Ludwig University Freiburg, Freiburg, Germany.

Purpose: To describe the clinical presentation and novel anatomical features of a patient with chronic central serous chorioretinopathy (CSCR) complicated by retinal neovascularization (RNV).

Observations: A 48 year-old patient with a long-standing history of bilateral CSCR presented to our clinic complaining about a sudden onset of tiny floaters. Multimodal imaging including fundus autofluorescence (FAF), fundus fluorescein (FA) and ICG angiography (ICG) and spectral domain optical coherence tomography (SD-OCT) confirmed the diagnosis of CSCR and revealed a pre-retinal neovascularization and concurring vitreous hemorrhage. Read More

Pan Afr Med J 2020 2;35. Epub 2020 Jan 2.

Department of Paediatrics and Adolescent Health, Faculty of Medicine, University of Botswana, Botswana.

We report a case of sight threatening vitreous haemorrhage and retinal detachment as complication of sickle cell disease (SCD). A 35 years old female Nigerian patient had presented to ophthalmology clinic of Princess Marina Hospital, Botswana, with two weeks history of poor vision in the left eye. The loss of vision was due to vitreous haemorrhage and retinal detachment which was confirmed by direct and indirect ophthalmoscopy and B-Scan ultrasound. Read More

J Fr Ophtalmol 2020 Apr 26;43(4):e147-e149. Epub 2020 Feb 26.

Service d'ophtalmologie A, institut Hédi Rais d'ophtalmologie de Tunis, boulevard 9-Avril, 1006 Tunis, Tunisie.

J Fr Ophtalmol 2020 Feb 26. Epub 2020 Feb 26.

Service d'ophtalmologie, CHU d'Amiens-Picardie, 1, rond-point du Professeur-Christian-Cabrol, 80054 Amiens, France. Electronic address:

Purpose: To analyse the clinical ocular characteristics and determine prognostic factors for functional recovery in eyes presenting with no light perception (NLP) after open globe ocular trauma.

Materials And Methods: In this retrospective study were included all the patients with no light perception after open globe trauma who presented to Amiens University Hospital between October 2014 and June 2018.

Results: Fifteen eyes of 15 patients were included in this study. Read More

Graefes Arch Clin Exp Ophthalmol 2020 Apr 28;258(4):869-878. Epub 2020 Feb 28.

Department of Ophthalmology, Charité University Medicine Berlin, Hindenburgdamm 30, 12200, Berlin, Germany.

Purpose: To demonstrate superiority of intravitreal ranibizumab 0.5 mg compared to focal and peripheral laser treatment in patients with radiation retinopathy for choroidal melanoma.

Methods: Inclusion criteria were as follows: patients with radiation retinopathy and visual acuity impairment due to radiation maculopathy accessible for laser therapy, age ≥ 18 years, and BCVA less than 20/32. Read More