3,662 results match your criteria Hemangiopericytoma


Whole-tumor histogram analysis of apparent diffusion coefficient in differentiating intracranial solitary fibrous tumor/hemangiopericytoma from angiomatous meningioma.

Eur J Radiol 2019 Mar 22;112:186-191. Epub 2019 Jan 22.

Department of Medical Imaging Center, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China. Electronic address:

Purpose: To assess the role of histogram analysis of apparent diffusion coefficient (ADC) maps based on whole-tumor in differentiating intracranial solitary fibrous tumor/hemangiopericytoma (SFT/HPC) from angiomatous meningioma (AM).

Materials And Methods: Pathologically confirmed intracranial SFT/HPC (n = 15) and AM (n = 20) were retrospectively collected and their clinical and conventional MRI features were analyzed. Diffusion-weighted (DW) images (b = 0 and 1000 s/mm) were processed with the mono-exponential model. Read More

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http://dx.doi.org/10.1016/j.ejrad.2019.01.023DOI Listing

18F-Choline PET/CT Imaging for Intracranial Hemangiopericytoma Recurrence.

Clin Nucl Med 2019 Feb 8. Epub 2019 Feb 8.

From the Departments of Nuclear Medicine and.

We report the case of a 50-year-old man, with previous history of grade 3 intracranial hemangiopericytoma with initial complete surgical resection, addressed for local recurrence. Surgical revision performed 18 months after initial surgery allowed only partial resection, leaving residual disease along the optic nerve. Complementary radiotherapy with proton was decided. Read More

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http://dx.doi.org/10.1097/RLU.0000000000002498DOI Listing
February 2019

[Retroperitoneal hemangiopericytoma-a rare case with multiple relapses-even 20 years after primary diagnosis].

Urologe A 2019 Feb 11. Epub 2019 Feb 11.

Klinik für Urologie und Kinderurologie, Universitätsklinikum Marburg, Philipps Universität Marburg, Baldingerstraße, 35039, Marburg, Deutschland.

A 41-year-old man without previous illness presented at our clinic with progressive pain in the lower abdomen and intermittent pain in the left flank. We found a lesion of unknown dignity which had anatomical contact to the bladder and rectum. Histological examination confirmed the diagnosis of hemangiopericytoma. Read More

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http://dx.doi.org/10.1007/s00120-019-0879-4DOI Listing
February 2019
1 Read

Coexistence of intracranial solitary fibrous tumor/hemangiopericytoma and right middle cerebral artery aneurysm.

J Surg Case Rep 2019 Jan 31;2019(1):rjz013. Epub 2019 Jan 31.

Department of Radiology, Section of Neuroradiology Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan, ROC.

Intracranial solitary fibrous tumors are rare mesenchymal neoplasms originating in the meninges and constitute a heterogeneous group of rare spindle cell tumors that include benign and malignant neoplasms of which hemangiopericytoma is nowadays considered a cellular phenotypic variant. From literatures, the incidence of coexistence of brain tumors and intracranial aneurysms is ~0.7-5. Read More

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http://dx.doi.org/10.1093/jscr/rjz013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354750PMC
January 2019
1 Read

Hemangiopericytoma of Gingiva in a 4-Year-Old Child: A Rare Case Report.

J Maxillofac Oral Surg 2019 Mar 1;18(1):52-56. Epub 2018 Mar 1.

2Department of Oral & Maxillofacial Surgery, Sudha Rustagi College of Dental Sciences & Research, Faridabad, Haryana India.

A hemangiopericytoma is a type of soft tissue sarcoma that originates in the pericytes in the walls of capillaries which was characterized in 1942. It is commonly seen in the age group of 5th-6th decades of adults and only 5-10% of cases occur in children with extreme rare occurrence in head and neck region (16%). A rare case of hemangiopericytoma in a 4-year-old female patient is presented here and its clinical, histopathological and immunohistochemically features are discussed. Read More

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http://dx.doi.org/10.1007/s12663-018-1086-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328836PMC

Intracranial Solitary Fibrous Tumors: a heterogeneous entity with an uncertain clinical behavior.

World Neurosurg 2019 Feb 1. Epub 2019 Feb 1.

Neurosurgery department Strasbourg UniversityHospital, Strasbourg France.

Intracranial solitary fibrous tumors (ISFT) are rare mesenchymal neoplasms, originating in the meninges, characterized by very different biological and clinical behaviors. Benign histotypes such as hemangiopericytomas are now considered a cellular phenotypic variant of this heterogeneous group of rare spindle-cell tumors. Due to their rarity and resemblance to other more common brain tumors, ISFTs are often poorly recognized and remain a diagnostic challenge: in fact, ISFT might either have a benign/indolent clinical behavior or show biological aggressivity with local and distant recurrences after surgery. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.01.142DOI Listing
February 2019

Apparent diffusion coefficient values in differential diagnosis and prognostic prediction of solitary of fibrous tumor/hemangiopericytoma (WHOII) and atypical meningioma.

Technol Health Care 2019 Jan 7. Epub 2019 Jan 7.

Department of Radiology, Shanghai General Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200080, China.

Background: It is difficult to distinguish solitary of fibrous tumor/hemangiopericytoma (SFT/HPC) from atypical meningioma (AM) by conventional imaging.As far as we know,diffusion weighting imaging may identify them effectively.

Objective: The purpose of this study was to determine the role of apparent diffusion coefficient (ADC) values to distinguish and predict prognosis of solitary of fibrous tumor/hemangiopericytoma (SFT/HPC) (WHOII) and atypical meningioma (AM). Read More

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http://dx.doi.org/10.3233/THC-181447DOI Listing
January 2019
1 Read

Solitary Fibrous Tumor of Pleura Invading into the Left Atrium via Pulmonary Vein.

Cureus 2018 Oct 22;10(10):e3473. Epub 2018 Oct 22.

Pulmonology, Maimonides Medical Center, Brooklyn, USA.

A 67-year-old woman came to the hospital because of difficulty in breathing. After an initial clinical assessment, contrast-enhanced computerized tomography (CT) of the chest revealed a well-circumscribed heterogeneous mass arising from the pleura adjacent to the superior and medial left pulmonary artery. The mass was invading the pulmonary vein and entering the left atrium. Read More

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http://dx.doi.org/10.7759/cureus.3473DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6318085PMC
October 2018

Rare Occurrence of an Intraocular Choroidal Solitary Fibrous Tumor/Hemangiopericytoma.

Ocul Oncol Pathol 2018 Jun 16;4(4):213-219. Epub 2017 Dec 16.

Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.

Purpose: Tumors previously diagnosed as solitary fibrous tumors (SFT) and hemangiopericytomas (HPC) are characterized by the fusion gene, leading to nuclear STAT6 expression, and are now considered part of one SFT/HPC tumor entity by the 2016 World Health Organization Classification of Tumors of the Central Nervous System. We present the first primary choroidal SFT/HPC with the diagnosis confirmed by STAT6 expression.

Procedures: A 51-year-old man underwent enucleation for a choroidal mass, which revealed a spindle cell neoplasm involving the optic nerve, without extrascleral extension. Read More

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http://dx.doi.org/10.1159/000481947DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322087PMC

[Solitary fibrous tumor/hemangiopericytoma of central nervous system: a clinicopathological analysis of 60 cases].

Zhonghua Bing Li Xue Za Zhi 2019 Jan;48(1):31-36

Department of Pathology, Nanjing Jinling Hospital, Nanjing 210002, China Guan Yu is working on the Department of Pathology, Xuzhou Mining Hospital, Jiangsu Province, Xuzhou 221006, China.

To investigate the clinical manifestations, imaging features, clinicopathologic features, and differential diagnosis of solitary fibrous tumors/anginoblastomas (SFT/HPCs) originating in the central nervous system. Sixty cases of SFT/HPCs originating in the central nervous system were collected at Nanjing Jinling Hospital, from January 1, 2008 to December 31, 2016. The clinical data, imaging data, histomorphologic changes and immunohistochemical finding were analyzed in the sixty cases. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0529-5807.2019.01.007DOI Listing
January 2019
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Recurrent Sinonasal CD34-Negative Malignant Solitary Fibrous Tumor Diagnosed on STAT6 Immunohistochemistry and NAB2-STAT6 Fusion.

Head Neck Pathol 2019 Jan 8. Epub 2019 Jan 8.

Department of Pathology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, 110029, India.

A spectrum of mesenchymal neoplasms occur in the sinonasal region. One of these is solitary fibrous tumor (SFT), a translocation-associated neoplasm characterized by NAB2-STAT6 gene fusion. Sinonasal SFTs characteristically display CD34 immunopositivity, which aids in diagnosis. Read More

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http://dx.doi.org/10.1007/s12105-018-00999-8DOI Listing
January 2019

Malignant solitary fibrous tumor in the subcutis: Report of a rare superficial malignant type and review of published work.

J Dermatol 2019 Jan 4. Epub 2019 Jan 4.

Department of Plastic Surgery, Kansai Medical University Medical Center, Osaka, Japan.

An 82-year-old Japanese man presented with a 90 mm × 80 mm subcutaneous nodule on the left chest, not connected to the pleura, described as hypointense on T -weighted magnetic resonance imaging. Histologically, a well-demarcated nodule demonstrated a patternless pattern composed of hemangiopericytoma-like and short storiform patterns from the subcutis into deeper tissue. Antler-like branching blood vessels and keloidal-type collagen bundles were seen. Read More

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http://dx.doi.org/10.1111/1346-8138.14755DOI Listing
January 2019

A rapidly fatal intracranial anaplastic hemangiopericytoma with de-novo dedifferentiation: emphasis on diagnostic recognition, molecular confirmation and discussion on treatment dilemma.

Brain Tumor Pathol 2019 Jan 2;36(1):20-26. Epub 2019 Jan 2.

Department of Pathology, National University Health System, 5 Lower Kent Ridge Road, 119074, Singapore, Singapore.

Solitary fibrous tumors/ hemangiopericytomas (SFT/HPC) are mesenchymal tumors that share a common genetic aberration and very rarely undergo dedifferentiation. We report a unique case of an intracranial anaplastic SFT/HPC with de-novo dedifferentiation, which pursued a rapidly fatal clinical course in a 41-year-old lady. The dedifferentiated component comprised a focal area of glandular formation with epithelial immunophenotype acquisition. Read More

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http://dx.doi.org/10.1007/s10014-018-0333-0DOI Listing
January 2019
1 Read

Solitary fibrous tumor.

Transl Gastroenterol Hepatol 2018 21;3:94. Epub 2018 Nov 21.

Department of Surgery, Indiana University School of Medicine, Indianapolis, IN, USA.

Solitary fibrous tumor (SFT) is a rare tumor of mesenchymal origin that account for less than 2% of all soft tissue masses. Initially identified in the pleura, SFT has been identified in multiple anatomic locations and can arise anywhere in the body. The varying histologic features along with non-specific means of identification have led SFT to be associated with several different names. Read More

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http://dx.doi.org/10.21037/tgh.2018.11.02DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286917PMC
November 2018

Unedited microneurosurgery of a solitary fibrous tumor of the pineal region.

Surg Neurol Int 2018 28;9:232. Epub 2018 Nov 28.

International Center for Neurosurgery, Henan Provincial People's Hospital, Zhengzhou, China.

Background: Solitary fibrous tumor/hemangiopericytoma is a new combined entity introduced in the 2016 World Health Organization classification of tumors of the central nervous system for grade I-III soft-tissue tumors. While grades II and III present more aggressive course and might require adjuvant radiochemotherapy, grade I tumors have a good outcome after gross total resection. In this video-abstract, we present an unedited microneurosurgery of a histologically confirmed benign solitary fibrous tumor of the pineal region performed by a senior author (JH). Read More

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http://dx.doi.org/10.4103/sni.sni_264_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287330PMC
November 2018

Sinonasal hemangiopericytoma caused hypophosphatemic osteomalacia: A case report.

Medicine (Baltimore) 2018 Dec;97(52):e13849

Department of Endocrinology and Metabolism, West China Hospital, Sichuan University, Chengdu.

Rationale: Tumor-induced osteomalacia (TIO) is a rare, paraneoplastic syndrome featured with fibroblast growth factor 23 (FGF23) secretion primarily by benign mesenchymal tumors and sometimes by malignancies. TIO diagnosis and treatment is often delayed because TIO usually has nonspecific generalized bone pain and weakness, and location of TIO tumor is quite challenging. Very few TIO caused by sinonasal hemangiopericytoma have been reported in the literature. Read More

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http://dx.doi.org/10.1097/MD.0000000000013849DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314754PMC
December 2018
1 Read
5.723 Impact Factor

Diagnosis and treatment of hemangiopericytoma in the central nervous system.

J Cancer Res Ther 2018 ;14(7):1578-1582

Department of Radiation Oncology, Chinese PLA General Hospital, Beijing, China.

Objective: This study aimed to explore the clinical characteristics and treatment of the hemangiopericytoma (HPC) in the central nervous system.

Materials And Methods: Clinical data from 14 patients with HPC in the central nervous system who were followed up for 12-107 months were retrospectively analyzed, and relevant literature was reviewed.

Results: All 14 patients underwent surgery and postoperative pathologic diagnosis, including 8 cases of total excision, 3 cases of subtotal excision, and 3 cases of partial excision. Read More

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http://dx.doi.org/10.4103/jcrt.JCRT_210_18DOI Listing
February 2019
11 Reads

The impact of histopathology and NAB2-STAT6 fusion subtype in classification and grading of meningeal solitary fibrous tumor/hemangiopericytoma.

Acta Neuropathol 2019 Feb 24;137(2):307-319. Epub 2018 Dec 24.

Anatomic Pathology, Department of Laboratory Medicine and Pathology, Mayo Clinic, 200 First Street, SW, Rochester, MN, 55905, USA.

Meningeal solitary fibrous tumor (SFT)/hemangiopericytoma (HPC) is a rare tumor with propensity for recurrence and metastasis. Although multiple classification schemes have been proposed, optimal risk stratification remains unclear, and the prognostic impact of fusion status is uncertain. We compared the 2016 WHO CNS tumor grading scheme (CNS-G), a three-tier system based on histopathologic phenotype and mitotic count, to the 2013 WHO soft-tissue counterpart (ST-G), a two-tier system based on mitotic count alone, in a cohort of 133 patients [59 female, 74 male; mean age 54 years (range 20-87)] with meningeal SFT/HPC. Read More

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http://link.springer.com/10.1007/s00401-018-1952-6
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http://dx.doi.org/10.1007/s00401-018-1952-6DOI Listing
February 2019
7 Reads

Solitary Fibrous Tumor/Hemangiopericytoma of Spinal Cord: A Retrospective Single-Center Study of 16 Cases.

World Neurosurg 2018 Dec 13. Epub 2018 Dec 13.

Department of Neurosurgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Objective: In this study, we retrospectively reviewed our experience in the surgical management of solitary fibrous tumor (SFT)/hemangiopericytomas (HPCs) of the spinal cord.

Methods: Sixteen patients with SFT/HPCs of the spinal cord were enrolled in this study. Data on clinical presentation, radiologic findings, histopathologic features, surgical treatment, adjuvant therapy, and prognosis were retrospectively reviewed. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.12.004DOI Listing
December 2018
15 Reads

A Case of Primary Intra-abdominal Synovial Sarcoma.

Indian J Surg Oncol 2018 Dec 22;9(4):636-639. Epub 2018 May 22.

2Department of General and Gastrointestinal Surgery, Medical Trust Hospital, M.G. Road, Kochi, Kerala 682016 India.

Synovial sarcomas are relatively common intermediate-to-high-grade malignant soft tissue tumors, often with an initial indolent course. And among the sarcomas primary intra-abdominal synovial sarcoma is a relatively rare entity that may present with an abdominal mass and diagnosis is usually confirmed by immunohistochemistry. The authors report a case of a 46-year-old man who presented with a large palpable abdominal mass. Read More

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http://dx.doi.org/10.1007/s13193-018-0783-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265165PMC
December 2018
1 Read

Activity of axitinib in progressive advanced solitary fibrous tumour: Results from an exploratory, investigator-driven phase 2 clinical study.

Eur J Cancer 2019 Jan 5;106:225-233. Epub 2018 Dec 5.

Medical Oncology Unit 2, Medical Oncology Department, Fondazione IRCCS Istituto Nazione dei Tumori, Milan, Italy; Medical Oncology and Hemato-Oncology Department, University of Milan, Milano, Italy.

Background: To explore the activity of axitinib in advanced solitary fibrous tumour (SFT).

Patients And Methods: In this investigator-driven phase II study on axitinib in advanced and progressive SFT, patients received axitinib, 5 mg bis in day (BID), until progression or limiting toxicity. Pathologic diagnosis was centrally reviewed, distinguishing malignant SFT (M-SFT) and high-grade/dedifferentiated SFT (HG/D-SFT) subtypes. Read More

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http://dx.doi.org/10.1016/j.ejca.2018.10.024DOI Listing
January 2019
2 Reads

Ultrasonic scalpel-assisted endoscopic endonasal surgery of infratemporal fossa: our first impressions.

World Neurosurg 2018 Dec 3. Epub 2018 Dec 3.

Division of Otorhinolaryngology, Department of Biotechnology and Life Sciences, HNS&FDRc, University of Insubria, Varese, Italy.

Background: Endoscopic endonasal transpterygoid approach is emerging as a valid option for treating selected tumors in the infratemporal fossa. Compared to traditional open approaches, the endoscopic endonasal approach (EEA) presents more difficulty in controlling bleeding and less choice in surgical instruments for endoscopic tumor dissection, which is often performed with bipolar forceps or steel dissectors.

Case Description: We describe the use of an ultrasonic scalpel device for performing endoscopic endonasal resection of two rare infratemporal fossa tumors (mature teratoma and hemangiopericytoma), which has not been reported in the literature so far. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S18788750183276
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http://dx.doi.org/10.1016/j.wneu.2018.11.202DOI Listing
December 2018
8 Reads

Intraspinal Dissemination and Local Recurrence of an Intracranial Hemangiopericytoma: Case Report.

World Neurosurg 2018 Nov 29. Epub 2018 Nov 29.

Department of Neurosurgery, University of Texas Southwestern Medical Center, Dallas, TX, USA.

Background: Hemangiopericytomas (HPCs) are rare vascular tumors that resemble meningiomas on imaging and have a high rate of local recurrence and metastases. There remains a paucity of data to guide management decisions of intraspinal dissemination of HPC in the literature, and none specifically related to anaplastic HPCs.

Case Description: Case report of a 34-year-old female with locally and distantly recurrent anaplastic hemangiopericytoma (HPC) (WHO grade III). Read More

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http://dx.doi.org/10.1016/j.wneu.2018.11.173DOI Listing
November 2018
1 Read

Solitary fibrous tumor of central nervous system masquerading as meninigioma: Report of a rare case.

Int J Surg Case Rep 2019 27;54:10-14. Epub 2018 Nov 27.

Deptt. of Pathology, PGIMS Rohtak, Haryana, India. Electronic address:

Introduction: Solitary fibrous tumor (SFT) is a rare neoplasm of mesenchymal origin that occurs most often in the visceral pleura. It rarely occurs in the central nervous system (CNS). If they occur intracranially, they are extra-axially located and develop from the meninges. Read More

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http://dx.doi.org/10.1016/j.ijscr.2018.11.063DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279985PMC
November 2018
1 Read

[Remarkable recovery in a patient with intradural extramedullary haemangiopericytoma: a case report and literature review].

Folia Neuropathol 2018 ;56(2):151-157

Haemangiopericytomas (HPCs) in the spinal canal are extremely rare and have only been infrequently reported. Severe and sustained spinal cord compression resulting from these intraspinal tumours may cause potentially irreversible neurological impairment. We described a rare case of primary intradural extramedullary HPC recovered from serious compression of thoracic spinal cord in a 65-year-old man suffered from a rapidly progressive disease with complete paralysis of the lower limbs. Read More

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http://dx.doi.org/10.5114/fn.2018.76620DOI Listing
January 2018
1 Read

Diffusion weighted imaging may help differentiate intracranial hemangiopericytoma from meningioma.

J Neuroradiol 2018 Nov 27. Epub 2018 Nov 27.

Department of Pathology, University of Manitoba, Winnipeg, Canada.

Background And Purpose: Hemangiopericytoma and meningioma appear similar on routine diagnostic imaging and hence are difficult to distinguish. The purpose of our study was to examine the diffusion weighted imaging (DWI) characteristics of these two types of tumours.

Methods: In a retrospective study, each patient with hemangiopericytoma was matched with two meningioma patients based on tumour location and size. Read More

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http://dx.doi.org/10.1016/j.neurad.2018.11.002DOI Listing
November 2018
6 Reads

Solitary fibrous tumor/hemangiopericytoma of the optic canal.

Clin Neuropathol 2019 Mar/Apr;38(2):74-79

Solitary fibrous tumor/hemangiopericytoma seldom arises from the optic nerve sheath. Herein, we describe the clinical, radiological, and histological findings of a solitary fibrous tumor/hemangiopericytoma arising from the optic nerve sheath and occupying the optic canal. The diagnosis is challenging both clinically and histologically as it clinically simulates a commoner lesion, i. Read More

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http://dx.doi.org/10.5414/NP301127DOI Listing
February 2019
2 Reads

Giant bilateral renal metastases from a meningeal hemangiopericytoma.

J Cancer Res Ther 2018 Oct-Dec;14(6):1434-1436

Urology Unit, Civil Hospital of Guastalla, Guastalla, RE, Italy.

We report the third case of bilateral metastatic renal meningeal hemangiopericytoma (HPC) 16 years after initial intracranial presentation. A 47-year-old male patient presented with abdominal mass drew our attention. Computed tomography (CT) demonstrated bilateral renal masses and another mass caudal to the lower pole of left kidney from which it was separated. Read More

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http://dx.doi.org/10.4103/0973-1482.187340DOI Listing
February 2019
1 Read

Clinical metric for differentiating intracranial hemangiopericytomas from meningiomas using diffusion weighted MRI.

Clin Imaging 2018 Nov 1;54:1-5. Epub 2018 Nov 1.

Department of Radiology, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Lenox Hill Hospital, 100 East 77th Street, New York, NY 10075, USA.

Purpose: Intracranial Hemangiopericytomas (IHP) are dural based tumors that frequently recur/metastasize. Unfortunately, their imaging appearance overlaps significantly with more benign meningiomas. We evaluated the use of diffusion weighted imaging (DWI) to differentiate IHP from meningioma. Read More

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http://dx.doi.org/10.1016/j.clinimag.2018.10.018DOI Listing
November 2018
2 Reads
0.596 Impact Factor

A Case Report of Meningeal Hemangiopericytoma: A 9-Year Journey from the Brain to the Spine.

World Neurosurg 2019 Feb 14;122:459-463. Epub 2018 Nov 14.

Division of Neurosurgery, Gilbert and Rose-Marie Chagoury School of Medicine, Lebanese American University, Beirut, Lebanon. Electronic address:

Background: Hemangiopericytomas (HPCs) are rare and aggressive vascular mesenchymal tumors. Unlike meningiomas, which have a similar radiologic appearance, these tumors have a higher risk of local recurrence after resection, and distant metastasis can reach up to 23%. Metastases to the vertebral bones from an intracranial HPC are very rare, with so far only 9 cases reported in the literature. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S18788750183257
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http://dx.doi.org/10.1016/j.wneu.2018.11.028DOI Listing
February 2019
18 Reads

Solitary fibrous tumor: an evolving and unifying entity with unsettled issues.

Histol Histopathol 2018 Nov 15:18064. Epub 2018 Nov 15.

Departments of Anatomic Pathology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan.

Solitary fibrous tumor (SFT) is a distinct fibroblastic neoplasm of intermediate biological potential, prototypically presenting as a pleura-associated tumor characterized by patternless proliferation of generally banal oval to spindle cells with hemangiopericytoma-like staghorn vessels in fibrocollagenous stroma. Over the past decades, the clinicopathological spectrum of SFT has been ever-expanding with the incorporation of cases exhibiting myxoid, giant cell-containing, and fat-forming histology, as well as those from extrathoracic sites, including the meninx. Atypical, frankly malignant and even dedifferentiated variants have also been recognized in a subset of SFTs. Read More

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http://www.hh.um.es/Abstracts/Vol_/_/__18064.htm
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http://dx.doi.org/10.14670/HH-18-064DOI Listing
November 2018
11 Reads

Very rare localization of a retroperitoneal hemangiopericytoma revealed by lumbosciatalgia: A case report.

Int J Surg Case Rep 2018 30;53:127-131. Epub 2018 Oct 30.

Department of Surgery, Sahloul Hospital, Sousse, Tunisia. Electronic address:

Introduction: Hemangiopericytoma is a rare vascular tumor representing about 1% of all vascular tumors and approximatively 5% of all soft tissues sarcomas that arises from the pericytes of Zimmerman surrounding capillaries and postcapillaries vessels. Retroperitoneal hemangiopericytomas are rare among the localisations as it usually occurs in lower and upper extremities.

Presentation Of Case: We present a case of 31-year-old man with a well-defined retro peritoneal mass measuring about 105 × 73 × 83 mm at right lower quadrant of the abdomen anterior to right psoas muscle. Read More

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http://dx.doi.org/10.1016/j.ijscr.2018.10.056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6216087PMC
October 2018
4 Reads

Pathological Features and Clinical Course in Patients With Recurrent or Malignant Orbital Solitary Fibrous Tumor/Hemangiopericytoma.

Ophthalmic Plast Reconstr Surg 2018 Oct 26. Epub 2018 Oct 26.

Orbital Oncology and Ophthalmic Plastic Surgery, Department of Plastic Surgery,*Department of Translational and Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, U.S.A.

Purpose: A risk assessment score for metastasis based on age, tumor size, and mitotic figures has been suggested for nonorbital solitary fibrous tumor (SFT)/hemangiopericytoma. The authors herein examine the clinicopathological features of recurrent and metastatic orbital SFT and evaluate the existing risk assessment score for orbital SFT.

Methods: The American Society of Ophthalmic Plastic and Reconstructive Surgery Oncology Database was queried for patients with recurrent or malignant orbital hemangiopericytoma/SFT. Read More

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http://Insights.ovid.com/crossref?an=00002341-900000000-9840
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http://dx.doi.org/10.1097/IOP.0000000000001189DOI Listing
October 2018
8 Reads

Solitary fibrous tumour of caecum wall: an unlikely cause of low gastrointestinal haemorrhage.

BMJ Case Rep 2018 Oct 25;2018. Epub 2018 Oct 25.

Anatomical Pathology, LAP-Laboratório Anatomia Patológica-Unilabs, Porto, Portugal.

Solitary fibrous tumour (SFT), previously denominated as haemangiopericytoma, is a rare, spindle cell neoplasm that was first described in the thoracic pleura. It is now known that this tumour may develop from almost any anatomic location. We report a case of SFT, in a 65-year-old man, which was located in the muscularis propria layer of the caecum with involvement of the serosa and the ileocecal appendix, location never described in the literature, and with an uncommon clinical presentation of hematochezia. Read More

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http://casereports.bmj.com/lookup/doi/10.1136/bcr-2018-22723
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http://dx.doi.org/10.1136/bcr-2018-227238DOI Listing
October 2018
11 Reads

Vascular tumours of the liver: a particular story.

Transl Gastroenterol Hepatol 2018 14;3:62. Epub 2018 Sep 14.

Institut de Recherche Expérimentale et Clinique, Université Catholique de Louvain (UCL), Brussels, Belgium.

Vascular tumours of the liver represent an underrated chapter of medical and surgical hepatology. These tumours cover a wide spectrum ranging from the frequent and most benign hepatic haemangioma (HH), via the rare and intermediately aggressive hepatic epithelioid haemangioendothelioma (HEHE) to the rare and most malignant hepatic haemangiosarcoma (HHS). In contrast to the treatment algorithms for hepatocellular and cholangiocellular cancer, the diagnostic and therapeutic approaches to HEHE and HHS are not well developed. Read More

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http://tgh.amegroups.com/article/view/4556/5328
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http://dx.doi.org/10.21037/tgh.2018.09.02DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182012PMC
September 2018
14 Reads

Oral and Extraoral Intermediate Tumors: Are MMP-9 and Ki-67 Biomarkers Correlated to Their High Recurrence Rates?

Appl Immunohistochem Mol Morphol 2018 Oct 24. Epub 2018 Oct 24.

Department of Oncology and Diagnostic Sciences, School of Dentistry, University of Maryland, Baltimore, MA.

Intermediate tumors of the head and neck fall in the borderline category. They are clinically aggressive tumors with no malignant phenotyping. They are locally infiltrative and have high recurrence rate with less chances to metastasize. Read More

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http://dx.doi.org/10.1097/PAI.0000000000000703DOI Listing
October 2018
6 Reads

Primary epidural hemangiopericytoma of the thoracic spine: Case report and literature review.

J Clin Neurosci 2019 Feb 21;60:142-147. Epub 2018 Oct 21.

Department of Orthopedics, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China.

Hemangiopericytoma (HPC) is a rare tumor originating from pericapillary cells. Rarely found in the central nervous system, it is extremely rare in the spinal canal. Because of the low incidence of this tumor, its radiographic features and clinical manifestations have not been extensively studied and reported, therefore, it is often misdiagnosed as a schwannoma or spinal meningioma. Read More

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http://dx.doi.org/10.1016/j.jocn.2018.10.057DOI Listing
February 2019
7 Reads

Osteoblastoma of the frontal bone invading the orbital roof: A case report.

Medicine (Baltimore) 2018 Oct;97(42):e12803

Department of General Surgery, Sir Run Run Shaw Hospital, Medical College, Zhejiang University, Hangzhou, China.

Rationale: Osteoblastoma is an uncommon primary bone tumor that involves any part of the skeleton. But its occurrence in the skull is extremely rare.

Patients Concerns: A 30-year-old female was admitted to our hospital, because of the mass in the right frontal region with the history of headache for 3 years without nausea or vomiting. Read More

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http://dx.doi.org/10.1097/MD.0000000000012803DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211925PMC
October 2018
3 Reads
5.723 Impact Factor

Metastatic craniocervical hemangiopericytoma presenting with hydrocephalus and papilledema - Case review.

J Clin Neurosci 2018 Oct 30;56:186-187. Epub 2018 Jun 30.

Department of Neurosurgery, Level 1, Old Baker Building, The Alfred Hospital, 55 Commercial Rd, Melbourne, Victoria 3004, Australia. Electronic address:

Hemangiopericytomas are rare mesenchymal tumors with propensity to recur locally and metastasize. We report the unique case of a fifty-five-year-old male with recurrence of a previously resected craniocervical hemangiopericytoma presenting with obstructive hydrocephalus secondary to new metastatic cerebellar deposits. Emergent surgical resection of the cerebellar hemangiopericytomas was performed prior to adjuvant radiotherapy. Read More

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http://dx.doi.org/10.1016/j.jocn.2018.06.031DOI Listing
October 2018
1 Read

Preoperative Prediction of Solitary Fibrous Tumor/Hemangiopericytoma and Angiomatous Meningioma Using Magnetic Resonance Imaging Texture Analysis.

World Neurosurg 2018 Dec 18;120:e1208-e1216. Epub 2018 Sep 18.

Department of Neurosurgery, Keio University School of Medicine, Tokyo, Japan.

Background: Solitary fibrous tumor (SFT)/hemangiopericytoma (HPC) is radiologically difficult to distinguish from meningioma, especially angiomatous meningioma. This study aimed to detect texture parameters to distinguish SFT/HPC from angiomatous meningioma using magnetic resonance imaging texture analysis with commercially available software.

Methods: We retrospectively investigated textural parameters in 43 newly diagnosed SFTs/HPCs, angiomatous meningiomas, and other World Health Organization (WHO) grade I meningiomas treated at Keio University Hospital. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.09.044DOI Listing
December 2018
1 Read

Meningeal solitary fibrous tumor/hemangiopericytoma: Emphasizing on STAT 6 immunohistochemistry with a review of literature.

Neurol India 2018 Sep-Oct;66(5):1419-1426

Department of Pathology and Laboratory Medicine, Aga Khan University Hospital, Karachi, Pakistan.

Background: The 2016 central nervous system (CNS) World Health Organisation (WHO) Update has merged the entities of meningeal solitary fibrous tumor (SFT) and hemangiopericytoma (HPC) into a single entity based on the presence of the nerve growth factor 1A (NGFI-A) binding protein 2 (NAB2)- signal transducer and activator of transcription 6 (STAT6) gene fusion in these tumors. Immunohistochemical (IHC) staining with STAT6 results in a strong nuclear positivity confirming the diagnosis. Meningeal SFT/HPCs are currently histologically graded according to a three-tiered system. Read More

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http://dx.doi.org/10.4103/0028-3886.241365DOI Listing
September 2018
1.084 Impact Factor

Canine spindle cell tumor mimicking human classical hemangiopericytoma.

J Vet Med Sci 2018 Nov 19;80(11):1728-1732. Epub 2018 Sep 19.

Laboratory of Veterinary Pathology, College of Bioresource Sciences, Nihon University, 1866 Kameino, Fujisawa, Kanagawa 252-0880, Japan.

The neoplastic mass developed in the left flank of a Border Collie dog. The tumor was resected surgically and evaluated histologically and immunohistochemically. Histologically a moderate number of spindle cells were proliferated with staghorn, placentoid, and myxoid growth patterns and a lack of perivascular whirling. Read More

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http://dx.doi.org/10.1292/jvms.18-0382DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261813PMC
November 2018

Renal solitary fibrous tumor/hemangiopericytoma: computed tomography findings and clinicopathologic features.

Abdom Radiol (NY) 2018 Sep 18. Epub 2018 Sep 18.

Department of Diagnostic Radiology, City of Hope National Medical Center, Duarte, CA, USA.

Purpose: To retrospectively characterize the clinical, pathological, and computed tomography (CT) findings of renal solitary fibrous tumor/hemangiopericytoma (rSFT/HPC).

Methods: Twelve patients with rSFT/HPCs were enrolled. The CT findings and clinicopathological features were retrospectively reviewed. Read More

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http://link.springer.com/10.1007/s00261-018-1777-8
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http://dx.doi.org/10.1007/s00261-018-1777-8DOI Listing
September 2018
6 Reads

Solitary Fibrous Tumour: A Single Institution Retrospective Study and Further Validation of a Prognostic Risk Assessment System.

Clin Oncol (R Coll Radiol) 2018 Dec 8;30(12):798-804. Epub 2018 Sep 8.

Department of Oncology, Aarhus University Hospital, Aarhus, Denmark.

Aims: Solitary fibrous tumour (SFT) is a rare mesenchymal-derived neoplasm that can arise in any anatomical location in the body. SFT rarely metastasises, but aggressive behaviour is seen in a minority of cases, and relapses can occur several years after treatment. It would be a clinical advantage if high-risk patients could be identified before treatment. Read More

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http://dx.doi.org/10.1016/j.clon.2018.08.015DOI Listing
December 2018
5 Reads

Preliminary feasibility study on differential diagnosis between radiation-induced cerebral necrosis and recurrent brain tumor by means of [F]fluoro-borono-phenylalanine PET/CT.

Ann Nucl Med 2018 Dec 7;32(10):702-708. Epub 2018 Sep 7.

Department of Nuclear Medicine and Tracer Kinetics, Osaka University Graduate School of Medicine, 2-2, Yamadaoka, Suita, Osaka, 565-0871, Japan.

Objectives: A previous study reported that a differential diagnosis between glioblastoma progression and radiation necrosis by 4-borono-2-[F]-fluoro-phenylalanine ([F]FBPA) PET can be made based on lesion-to-normal ratio of [F]FBPA accumulation. Two-dimensional data acquisition mode PET alone system, with in-plane resolution of 7.9 mm and axial resolution of 13. Read More

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http://dx.doi.org/10.1007/s12149-018-1296-2DOI Listing
December 2018
9 Reads

Pathological prognostic markers in central nervous system solitary fibrous tumour/hemangiopericytoma: Evidence from a small series.

PLoS One 2018 5;13(9):e0203570. Epub 2018 Sep 5.

Pathology Unit, Department of Medical Sciences, University of Turin, Turin, Italy.

Background: Primary central nervous system (CNS) solitary fibrous tumour/hemangiopericytoma (SFT/HPC) is a rare neoplasm and its classification criteria have been redefined by the latest WHO Classification of CNS Tumours. Outcome can vary significantly among patients, thus reliable prognostic markers are warranted.

Methods: Primary CNS SFT/HPC diagnosed at the Pathology Unit of our Institution between 2006 and 2016 were retrospectively collected. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0203570PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6124774PMC
September 2018
5 Reads

Diagnosis and treatment of solitary fibrous tumor/hemangiopericytoma of central nervous system. Retrospective report of 17 patients and literature review.

Neuro Endocrinol Lett 2018 05;39(2):88-94

Department of Neurosurgery, China-Japan Union Hospital, JiLin University, China.

To investigate the diagnosis, treatment and prognosis of solitary fibrous tumor (SFT)/ hemangiopericytoma (HPC) of central nervous system (CNS), we retrospectively reviewed records of 17 patients who were treated for CNS SFT/HPC at the Department of Neurosurgery, China-Japan Union Hospital of Jilin University from December 2010 to June 2016, and reevaluated their pathological diagnoses according to the 2016 WHO classification of CNS tumors. We then analyzed their clinical symptoms, imaging characteristics, treatments and outcomes. Clinical manifestations of CNS SFT/HPC were diverse, but mainly included headache, increased intracranial pressure, seizures, and focal neurological deficits. Read More

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May 2018
3 Reads

[Clinical and pathologic features of solitary fibrous tumor/hemangiopericytoma of central nervous system].

Zhonghua Zhong Liu Za Zhi 2018 Aug;40(8):635-637

Department of Pathology, The First Affiliated Hospital of Soochow University, 215000 Suzhou, China.

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http://dx.doi.org/10.3760/cma.j.issn.0253-3766.2018.08.014DOI Listing
August 2018
1 Read

A novel mouse model of hemangiopericytoma due to loss of Tsc2.

Hum Mol Genet 2018 Dec;27(24):4169-4175

Division of Pulmonary Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

Hemangiopericytoma (HPC) is a rare vascular tumor, which is thought to originate from pericytes. However, no direct evidence for the cell of origin has been found, and the mechanism of HPC tumorigenesis is poorly understood. Here we report that loss of the tumor suppressor gene Tsc2 in pericytes using a FoxD1 promoter driven cre allele (Foxd1tm1(GFP/cre) Amc, FoxD1GC) leads to the formation of HPC in multiple sites. Read More

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http://dx.doi.org/10.1093/hmg/ddy289DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276833PMC
December 2018
65 Reads
6.393 Impact Factor

The radiation therapy options of intracranial hemangiopericytoma: An overview and update on a rare vascular mesenchymal tumor.

Oncol Rev 2018 Jul 10;12(2):354. Epub 2018 Jul 10.

Department of Interdisciplinary Medicine, Section of Diagnostic Imaging and Radiotherapy, University Aldo Moro, Bari, Italy.

Hemangiopericytoma (HPC) is an extremely rare hypervascular tumor of mesenchymal lineage. It tends to recur and to develop distant metastases even many years after primary surgical resection. The management of recurrent and metastatic disease is not always so well defined. Read More

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http://dx.doi.org/10.4081/oncol.2018.354DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6068394PMC
July 2018
2 Reads