3,642 results match your criteria Hemangiopericytoma
Indian J Surg Oncol 2018 Dec 22;9(4):636-639. Epub 2018 May 22.
2Department of General and Gastrointestinal Surgery, Medical Trust Hospital, M.G. Road, Kochi, Kerala 682016 India.
Synovial sarcomas are relatively common intermediate-to-high-grade malignant soft tissue tumors, often with an initial indolent course. And among the sarcomas primary intra-abdominal synovial sarcoma is a relatively rare entity that may present with an abdominal mass and diagnosis is usually confirmed by immunohistochemistry. The authors report a case of a 46-year-old man who presented with a large palpable abdominal mass. Read More
Eur J Cancer 2018 Dec 5;106:225-233. Epub 2018 Dec 5.
Medical Oncology Unit 2, Medical Oncology Department, Fondazione IRCCS Istituto Nazione dei Tumori, Milan, Italy; Medical Oncology and Hemato-Oncology Department, University of Milan, Milano, Italy.
Background: To explore the activity of axitinib in advanced solitary fibrous tumour (SFT).
Patients And Methods: In this investigator-driven phase II study on axitinib in advanced and progressive SFT, patients received axitinib, 5 mg bis in day (BID), until progression or limiting toxicity. Pathologic diagnosis was centrally reviewed, distinguishing malignant SFT (M-SFT) and high-grade/dedifferentiated SFT (HG/D-SFT) subtypes. Read More
World Neurosurg 2018 Dec 3. Epub 2018 Dec 3.
Division of Otorhinolaryngology, Department of Biotechnology and Life Sciences, HNS&FDRc, University of Insubria, Varese, Italy.
Background: Endoscopic endonasal transpterygoid approach is emerging as a valid option for treating selected tumors in the infratemporal fossa. Compared to traditional open approaches, the endoscopic endonasal approach (EEA) presents more difficulty in controlling bleeding and less choice in surgical instruments for endoscopic tumor dissection, which is often performed with bipolar forceps or steel dissectors.
Case Description: We describe the use of an ultrasonic scalpel device for performing endoscopic endonasal resection of two rare infratemporal fossa tumors (mature teratoma and hemangiopericytoma), which has not been reported in the literature so far. Read More
World Neurosurg 2018 Nov 29. Epub 2018 Nov 29.
Department of Neurosurgery, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Background: Hemangiopericytomas (HPCs) are rare vascular tumors that resemble meningiomas on imaging and have a high rate of local recurrence and metastases. There remains a paucity of data to guide management decisions of intraspinal dissemination of HPC in the literature, and none specifically related to anaplastic HPCs.
Case Description: Case report of a 34-year-old female with locally and distantly recurrent anaplastic hemangiopericytoma (HPC) (WHO grade III). Read More
Int J Surg Case Rep 2018 Nov 27;54:10-14. Epub 2018 Nov 27.
Deptt. of Pathology, PGIMS Rohtak, Haryana, India. Electronic address:
Introduction: Solitary fibrous tumor (SFT) is a rare neoplasm of mesenchymal origin that occurs most often in the visceral pleura. It rarely occurs in the central nervous system (CNS). If they occur intracranially, they are extra-axially located and develop from the meninges. Read More
Folia Neuropathol 2018 ;56(2):151-157
Haemangiopericytomas (HPCs) in the spinal canal are extremely rare and have only been infrequently reported. Severe and sustained spinal cord compression resulting from these intraspinal tumours may cause potentially irreversible neurological impairment. We described a rare case of primary intradural extramedullary HPC recovered from serious compression of thoracic spinal cord in a 65-year-old man suffered from a rapidly progressive disease with complete paralysis of the lower limbs. Read More
J Neuroradiol 2018 Nov 27. Epub 2018 Nov 27.
Department of Pathology, University of Manitoba, Winnipeg, Canada.
Background And Purpose: Hemangiopericytoma and meningioma appear similar on routine diagnostic imaging and hence are difficult to distinguish. The purpose of our study was to examine the diffusion weighted imaging (DWI) characteristics of these two types of tumours.
Methods: In a retrospective study, each patient with hemangiopericytoma was matched with two meningioma patients based on tumour location and size. Read More
Clin Neuropathol 2018 Nov 30. Epub 2018 Nov 30.
Solitary fibrous tumor/hemangiopericytoma seldom arises from the optic nerve sheath. Herein, we describe the clinical, radiological, and histological findings of a solitary fibrous tumor/hemangiopericytoma arising from the optic nerve sheath and occupying the optic canal. The diagnosis is challenging both clinically and histologically as it clinically simulates a commoner lesion, i. Read More
J Cancer Res Ther 2018 Oct-Dec;14(6):1434-1436
Urology Unit, Civil Hospital of Guastalla, Guastalla, RE, Italy.
We report the third case of bilateral metastatic renal meningeal hemangiopericytoma (HPC) 16 years after initial intracranial presentation. A 47-year-old male patient presented with abdominal mass drew our attention. Computed tomography (CT) demonstrated bilateral renal masses and another mass caudal to the lower pole of left kidney from which it was separated. Read More
Clin Imaging 2018 Nov 1;54:1-5. Epub 2018 Nov 1.
Department of Radiology, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Lenox Hill Hospital, 100 East 77th Street, New York, NY 10075, USA.
Purpose: Intracranial Hemangiopericytomas (IHP) are dural based tumors that frequently recur/metastasize. Unfortunately, their imaging appearance overlaps significantly with more benign meningiomas. We evaluated the use of diffusion weighted imaging (DWI) to differentiate IHP from meningioma. Read More
World Neurosurg 2018 Nov 14. Epub 2018 Nov 14.
Division of Neurosurgery, Gilbert and Rose-Marie Chagoury School of Medicine, Lebanese American University, Beirut, Lebanon. Electronic address:
Background And Importance: Hemangiopericytomas (HPC) are rare and aggressive vascular mesenchymal tumors. Unlike meningiomas which have a similar radiological appearance, these tumors have a higher risk of local recurrence after resection, and distant metastasis can reach up to 23%. Metastases to the vertebral bones from an intracranial HPC are very rare, with so far only 9 cases reported in the literature. Read More
Histol Histopathol 2018 Nov 15:18064. Epub 2018 Nov 15.
Departments of Anatomic Pathology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan.
Solitary fibrous tumor (SFT) is a distinct fibroblastic neoplasm of intermediate biological potential, prototypically presenting as a pleura-associated tumor characterized by patternless proliferation of generally banal oval to spindle cells with hemangiopericytoma-like staghorn vessels in fibrocollagenous stroma. Over the past decades, the clinicopathological spectrum of SFT has been ever-expanding with the incorporation of cases exhibiting myxoid, giant cell-containing, and fat-forming histology, as well as those from extrathoracic sites, including the meninx. Atypical, frankly malignant and even dedifferentiated variants have also been recognized in a subset of SFTs. Read More
Int J Surg Case Rep 2018 Oct 30;53:127-131. Epub 2018 Oct 30.
Department of Surgery, Sahloul Hospital, Sousse, Tunisia. Electronic address:
Introduction: Hemangiopericytoma is a rare vascular tumor representing about 1% of all vascular tumors and approximatively 5% of all soft tissues sarcomas that arises from the pericytes of Zimmerman surrounding capillaries and postcapillaries vessels. Retroperitoneal hemangiopericytomas are rare among the localisations as it usually occurs in lower and upper extremities.
Presentation Of Case: We present a case of 31-year-old man with a well-defined retro peritoneal mass measuring about 105 × 73 × 83 mm at right lower quadrant of the abdomen anterior to right psoas muscle. Read More
Ophthalmic Plast Reconstr Surg 2018 Oct 26. Epub 2018 Oct 26.
Orbital Oncology and Ophthalmic Plastic Surgery, Department of Plastic Surgery,*Department of Translational and Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, U.S.A.
Purpose: A risk assessment score for metastasis based on age, tumor size, and mitotic figures has been suggested for nonorbital solitary fibrous tumor (SFT)/hemangiopericytoma. The authors herein examine the clinicopathological features of recurrent and metastatic orbital SFT and evaluate the existing risk assessment score for orbital SFT.
Methods: The American Society of Ophthalmic Plastic and Reconstructive Surgery Oncology Database was queried for patients with recurrent or malignant orbital hemangiopericytoma/SFT. Read More
BMJ Case Rep 2018 Oct 25;2018. Epub 2018 Oct 25.
Anatomical Pathology, LAP-Laboratório Anatomia Patológica-Unilabs, Porto, Portugal.
Solitary fibrous tumour (SFT), previously denominated as haemangiopericytoma, is a rare, spindle cell neoplasm that was first described in the thoracic pleura. It is now known that this tumour may develop from almost any anatomic location. We report a case of SFT, in a 65-year-old man, which was located in the muscularis propria layer of the caecum with involvement of the serosa and the ileocecal appendix, location never described in the literature, and with an uncommon clinical presentation of hematochezia. Read More
Transl Gastroenterol Hepatol 2018 14;3:62. Epub 2018 Sep 14.
Institut de Recherche Expérimentale et Clinique, Université Catholique de Louvain (UCL), Brussels, Belgium.
Vascular tumours of the liver represent an underrated chapter of medical and surgical hepatology. These tumours cover a wide spectrum ranging from the frequent and most benign hepatic haemangioma (HH), via the rare and intermediately aggressive hepatic epithelioid haemangioendothelioma (HEHE) to the rare and most malignant hepatic haemangiosarcoma (HHS). In contrast to the treatment algorithms for hepatocellular and cholangiocellular cancer, the diagnostic and therapeutic approaches to HEHE and HHS are not well developed. Read More
Appl Immunohistochem Mol Morphol 2018 Oct 24. Epub 2018 Oct 24.
Department of Oncology and Diagnostic Sciences, School of Dentistry, University of Maryland, Baltimore, MA.
Intermediate tumors of the head and neck fall in the borderline category. They are clinically aggressive tumors with no malignant phenotyping. They are locally infiltrative and have high recurrence rate with less chances to metastasize. Read More
J Clin Neurosci 2018 Oct 21. Epub 2018 Oct 21.
Department of Orthopedics, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China.
Hemangiopericytoma (HPC) is a rare tumor originating from pericapillary cells. Rarely found in the central nervous system, it is extremely rare in the spinal canal. Because of the low incidence of this tumor, its radiographic features and clinical manifestations have not been extensively studied and reported, therefore, it is often misdiagnosed as a schwannoma or spinal meningioma. Read More
Medicine (Baltimore) 2018 Oct;97(42):e12803
Department of General Surgery, Sir Run Run Shaw Hospital, Medical College, Zhejiang University, Hangzhou, China.
Rationale: Osteoblastoma is an uncommon primary bone tumor that involves any part of the skeleton. But its occurrence in the skull is extremely rare.
Patients Concerns: A 30-year-old female was admitted to our hospital, because of the mass in the right frontal region with the history of headache for 3 years without nausea or vomiting. Read More
J Clin Neurosci 2018 Oct 30;56:186-187. Epub 2018 Jun 30.
Department of Neurosurgery, Level 1, Old Baker Building, The Alfred Hospital, 55 Commercial Rd, Melbourne, Victoria 3004, Australia. Electronic address:
Hemangiopericytomas are rare mesenchymal tumors with propensity to recur locally and metastasize. We report the unique case of a fifty-five-year-old male with recurrence of a previously resected craniocervical hemangiopericytoma presenting with obstructive hydrocephalus secondary to new metastatic cerebellar deposits. Emergent surgical resection of the cerebellar hemangiopericytomas was performed prior to adjuvant radiotherapy. Read More
World Neurosurg 2018 Dec 18;120:e1208-e1216. Epub 2018 Sep 18.
Department of Neurosurgery, Keio University School of Medicine, Tokyo, Japan.
Background: Solitary fibrous tumor (SFT)/hemangiopericytoma (HPC) is radiologically difficult to distinguish from meningioma, especially angiomatous meningioma. This study aimed to detect texture parameters to distinguish SFT/HPC from angiomatous meningioma using magnetic resonance imaging texture analysis with commercially available software.
Methods: We retrospectively investigated textural parameters in 43 newly diagnosed SFTs/HPCs, angiomatous meningiomas, and other World Health Organization (WHO) grade I meningiomas treated at Keio University Hospital. Read More
Neurol India 2018 Sep-Oct;66(5):1419-1426
Department of Pathology and Laboratory Medicine, Aga Khan University Hospital, Karachi, Pakistan.
Background: The 2016 central nervous system (CNS) World Health Organisation (WHO) Update has merged the entities of meningeal solitary fibrous tumor (SFT) and hemangiopericytoma (HPC) into a single entity based on the presence of the nerve growth factor 1A (NGFI-A) binding protein 2 (NAB2)- signal transducer and activator of transcription 6 (STAT6) gene fusion in these tumors. Immunohistochemical (IHC) staining with STAT6 results in a strong nuclear positivity confirming the diagnosis. Meningeal SFT/HPCs are currently histologically graded according to a three-tiered system. Read More
J Vet Med Sci 2018 Nov 19;80(11):1728-1732. Epub 2018 Sep 19.
Laboratory of Veterinary Pathology, College of Bioresource Sciences, Nihon University, 1866 Kameino, Fujisawa, Kanagawa 252-0880, Japan.
The neoplastic mass developed in the left flank of a Border Collie dog. The tumor was resected surgically and evaluated histologically and immunohistochemically. Histologically a moderate number of spindle cells were proliferated with staghorn, placentoid, and myxoid growth patterns and a lack of perivascular whirling. Read More
Abdom Radiol (NY) 2018 Sep 18. Epub 2018 Sep 18.
Department of Diagnostic Radiology, City of Hope National Medical Center, Duarte, CA, USA.
Purpose: To retrospectively characterize the clinical, pathological, and computed tomography (CT) findings of renal solitary fibrous tumor/hemangiopericytoma (rSFT/HPC).
Methods: Twelve patients with rSFT/HPCs were enrolled. The CT findings and clinicopathological features were retrospectively reviewed. Read More
Clin Oncol (R Coll Radiol) 2018 Dec 8;30(12):798-804. Epub 2018 Sep 8.
Department of Oncology, Aarhus University Hospital, Aarhus, Denmark.
Aims: Solitary fibrous tumour (SFT) is a rare mesenchymal-derived neoplasm that can arise in any anatomical location in the body. SFT rarely metastasises, but aggressive behaviour is seen in a minority of cases, and relapses can occur several years after treatment. It would be a clinical advantage if high-risk patients could be identified before treatment. Read More
Ann Nucl Med 2018 Dec 7;32(10):702-708. Epub 2018 Sep 7.
Department of Nuclear Medicine and Tracer Kinetics, Osaka University Graduate School of Medicine, 2-2, Yamadaoka, Suita, Osaka, 565-0871, Japan.
Objectives: A previous study reported that a differential diagnosis between glioblastoma progression and radiation necrosis by 4-borono-2-[F]-fluoro-phenylalanine ([F]FBPA) PET can be made based on lesion-to-normal ratio of [F]FBPA accumulation. Two-dimensional data acquisition mode PET alone system, with in-plane resolution of 7.9 mm and axial resolution of 13. Read More
PLoS One 2018 5;13(9):e0203570. Epub 2018 Sep 5.
Pathology Unit, Department of Medical Sciences, University of Turin, Turin, Italy.
Background: Primary central nervous system (CNS) solitary fibrous tumour/hemangiopericytoma (SFT/HPC) is a rare neoplasm and its classification criteria have been redefined by the latest WHO Classification of CNS Tumours. Outcome can vary significantly among patients, thus reliable prognostic markers are warranted.
Methods: Primary CNS SFT/HPC diagnosed at the Pathology Unit of our Institution between 2006 and 2016 were retrospectively collected. Read More
Neuro Endocrinol Lett 2018 05;39(2):88-94
Department of Neurosurgery, China-Japan Union Hospital, JiLin University, China.
To investigate the diagnosis, treatment and prognosis of solitary fibrous tumor (SFT)/ hemangiopericytoma (HPC) of central nervous system (CNS), we retrospectively reviewed records of 17 patients who were treated for CNS SFT/HPC at the Department of Neurosurgery, China-Japan Union Hospital of Jilin University from December 2010 to June 2016, and reevaluated their pathological diagnoses according to the 2016 WHO classification of CNS tumors. We then analyzed their clinical symptoms, imaging characteristics, treatments and outcomes. Clinical manifestations of CNS SFT/HPC were diverse, but mainly included headache, increased intracranial pressure, seizures, and focal neurological deficits. Read More
Zhonghua Zhong Liu Za Zhi 2018 Aug;40(8):635-637
Department of Pathology, The First Affiliated Hospital of Soochow University, 215000 Suzhou, China.
Hum Mol Genet 2018 Dec;27(24):4169-4175
Division of Pulmonary Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Hemangiopericytoma (HPC) is a rare vascular tumor, which is thought to originate from pericytes. However, no direct evidence for the cell of origin has been found, and the mechanism of HPC tumorigenesis is poorly understood. Here we report that loss of the tumor suppressor gene Tsc2 in pericytes using a FoxD1 promoter driven cre allele (Foxd1tm1(GFP/cre) Amc, FoxD1GC) leads to the formation of HPC in multiple sites. Read More
Oncol Rev 2018 Jul 10;12(2):354. Epub 2018 Jul 10.
Department of Interdisciplinary Medicine, Section of Diagnostic Imaging and Radiotherapy, University Aldo Moro, Bari, Italy.
Hemangiopericytoma (HPC) is an extremely rare hypervascular tumor of mesenchymal lineage. It tends to recur and to develop distant metastases even many years after primary surgical resection. The management of recurrent and metastatic disease is not always so well defined. Read More
J Neurosurg 2018 Aug 3:1-6. Epub 2018 Aug 3.
Departments of 1 Neurological Surgery and.
OBJECTIVE The endoscopic endonasal transcavernous approach with interdural pituitary transposition provides surgical access to the posterior clinoids and interpeduncular cistern. Prior to posterior clinoidectomy, selective coagulation and transection of the inferior hypophyseal artery (IHA) is recommended to prevent uncontrolled tearing of the artery and its avulsion from the wall of the cavernous carotid artery. The authors' preliminary experience has shown that unilateral sacrifice of the IHA caused no permanent endocrine dysfunction. Read More
Clin Nucl Med 2018 Sep;43(9):e331-e333
Nuclear Medicine and PET, Mahatma Gandhi Cancer Hospital and Research Institute, MVP Colony, Visakhapatnam, Andhra Pradesh, India.
We present a 53 year old woman initially diagnosed as hemangiopericytoma in the posterior fossa on the right side post excision with immunohistochemistry staining for CD34 being positive. Presently, the patient had difficulty in walking due to back pain and pain in left arm. Imaging with F-FDG PET showed low glucose avidity in disease sites but Ga-PSMA PET unequivocally demonstrated multiple skeletal and liver metastases with intense PSMA avidity. Read More
Neurosurgery 2018 Mar;82(3):365-371
Faculty of Medicine, University of Oslo, Oslo, Norway.
Background: To date, the traditional approach to intraspinal tumors has been open laminectomy or laminoplasty followed by microsurgical tumor resection. Recently, however, minimally invasive approaches have been attempted by some.
Objective: To investigate the feasibility and safety of minimally invasive surgery (MIS) for primary intradural spinal tumors. Read More
J Surg Case Rep 2018 May 14;2018(5):rjy087. Epub 2018 May 14.
Department of General Surgery, Koutlimbaneio and Triantafylleio General Hospital of Larisa, Tsakalof 1, Larisa, Greece.
Haemangiopericytomas (HPC) are highly vascularized tumours located in any part of the body where capillaries can be found. Since 2002, they have been re-classified under the umbrella 'extrapleural Solitary Fibrous Tumour (SFT)' and the term HPC is nowadays used to describe a growth pattern rather than a clinical entity. Their biological behaviour varies and they require a long-term follow-up since they may recur or metastasise several years after successful treatment. Read More
Ann Maxillofac Surg 2018 Jan-Jun;8(1):151-153
Department of Dentistry and Maxillofacial Surgery, AIIMS, Raipur, Chhattisgarh, India.
Hemangiopericytomas (HPCs)/Solitary fibrous tumor are rare neoplasms of vascular origin that occur in head-and-neck region. These tumors arise from capillary pericytes and are difficult to distinguish from other tumors of vascular origin. HPC, initially described by Stout and Murray in 1942, usually occur in the fifth decade of life and account for 3%-5% of all soft-tissue sarcomas and 1% of all vascular tumors. Read More
Int J Surg Pathol 2018 Dec 2;26(8):772-776. Epub 2018 Jul 2.
1 Department of Pathology and Laboratories, Fundación Santa Fe de Bogotá, Bogotá DC, Colombia.
Solitary fibrous tumor (SFT) is a spindle-shaped cell neoplasm originally described in the pleura, but subsequently found in many anatomic sites. Only few cases of primary SFTs in the bone have been previously described in the literature. We present the case of an 86-year-old man with a 1-week history of pain in his left arm. Read More
J Oncol Pharm Pract 2018 Jan 1:1078155218784760. Epub 2018 Jan 1.
Provincial Pharmacy, Systemic Therapy Program, BC Cancer Agency, Vancouver, Canada.
Background Patients with locally advanced, recurrent or metastatic solitary fibrous tumour are often treated with bevacizumab and temozolomide based on the clinical efficacy reported in a case series of 14 patients. Given the rarity of solitary fibrous tumour, large trials are not feasible. We report the efficacy of this regimen based on a population-based analysis. Read More
Oncol Lett 2018 Jul 8;16(1):580-584. Epub 2018 May 8.
Department of Pathology, Anhui Provincial Hospital, Hefei, Anhui 230001, P.R. China.
Undifferentiated sinonasal malignant melanoma (MM) is a rare type of tumor, which can be easily misdiagnosed. The present study reports a 41-year-old male patient who presented with a 4-day history of epistaxis. Clinical examination and radiological imaging lead to the detection of a mass in the right sinonasal region. Read More
Neurosurgery 2018 Jun 8. Epub 2018 Jun 8.
Department of Neurosurgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
Background And Importance: Myopericytoma is an emerging class of neoplasm originating from the perivascular myoid cellular environment, previously classified as a variant of hemangiopericytoma. Most reported myopericytomas are found in soft tissues of the extremities; however, infrequent cases are described involving the central nervous system. Intracranial myopericytoma remains rare. Read More
Indian J Surg Oncol 2018 Jun 2;9(2):256-259. Epub 2018 Mar 2.
1Department of Gastrointestinal Surgery and Liver Transplantation, All India Institute of Medical Sciences, New Delhi, India.
Isolated, metastatic hemangiopericytoma of liver is an extremely rare entity. We present a case of hemangiopericytoma of the liver, metastatic from a meningeal hemangiopericytoma, who presented 10 years after the surgical excision of the primary tumour and morphologically mimicked a hepatocellular carcinoma. We review the literature regarding this entity and discuss the difficulties in preoperative diagnosis and the need for a thorough preoperative evaluation. Read More
Ci Ji Yi Xue Za Zhi 2018 Apr-Jun;30(2):119-121
Department of Otolaryngology, Taichung Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Taichung, Taiwan.
A glomangiopericytoma, or sinonasal type hemangiopericytoma, is a rare lesion which accounts for <0.5% of all sinonasal tumors. The mainstay treatment is wide excision. Read More
Am J Surg Pathol 2018 Oct;42(10):1275-1285
Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.
Biphenotypic sinonasal sarcoma (BSNS) is a distinctive, anatomically restricted, low-grade spindle cell sarcoma that shows considerable histologic overlap with other cellular spindle cell neoplasms. This tumor type shows both myogenic and neural differentiation, which can be demonstrated by immunohistochemistry; however, the available diagnostic markers are relatively nonspecific. BSNS is characterized by PAX3 rearrangements, with MAML3 as the most common fusion partner. Read More
Ann Neurosci 2018 May 22;24(4):207-211. Epub 2017 Aug 22.
Department of Histopathology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.
Extra-axial central nervous system lesions can occasionally involve the overlying calvarium. The involvement may be due to longstanding pressure effects or secondary to the aggressive behaviour of the lesion. The spectrum of such dural-based lesions varies from infectious/inflammatory to neoplastic etiology. Read More
Arch Pathol Lab Med 2018 Jun;142(6):761-766
From the Department of Pathology & Laboratory Medicine, Geisel School of Medicine at Dartmouth, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire.
Solitary fibrous tumor (SFT) is a unique mesenchymal neoplasm that was originally believed to be of submesothelial origin. Eventually, SFT expanded to include what was previously called hemangiopericytoma in other regions of the body that had similar immunohistochemical and morphologic features. Although most are benign, many studies have tried to identify histologic features that predict which tumors will behave in an aggressive manner. Read More
Oper Neurosurg (Hagerstown) 2018 May 24. Epub 2018 May 24.
Department of Neurosurgery, Clinical Neurosciences Center, University of Utah, Salt Lake City, Utah.
A 22-yr-old female college athlete had noted ataxia during competitive gymnastic events. Magnetic resonance imaging revealed a large tumor compatible with preoperative diagnosis of meningioma arising from the petrotentorial region with marked brainstem compression. The technical challenges associated with this removal include safe dissection of cranial nerves IV to VIII and dissection from the brainstem and cerebellum, taking care to not interfere with blood supply to these structures. Read More
Eye Vis (Lond) 2018 13;5:10. Epub 2018 May 13.
Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Qazvin Sq, Tehran, 1336616351 Iran.
Background: Hemangiopericytoma and solitary fibrous tumor are considered related variants on the same spectrum and both may essentially be the same tumor. They are infrequently encountered in the orbital region while the zygomatic bone is an extremely rare location for these neoplasms to occur.
Case Presentation: A 14-year-old boy presented with complaint of deformity of left infraorbital area and a firm, regular mass in the region. Read More
Orbit 2018 May 21:1-3. Epub 2018 May 21.
a Department of Ophthalmology and Visual Sciences , University of Illinois Chicago , Chicago , IL , USA.
We report the case of an anterior orbital tumor in a young woman that enlarged during pregnancy. The mass was excised and found to be a spindle cell tumor with immunohistochemical reactivity consistent with a solitary fibrous tumor, a rare entity in the spectrum of fibroblastic mesenchymal tumors. The tumor was strongly positive for the progesterone receptor, consistent with its clinical growth during the antenatal and postnatal periods. Read More
J Med Imaging Radiat Oncol 2018 May 19. Epub 2018 May 19.
Department of Radiation Oncology, Epworth Healthcare, Melbourne, Victoria, Australia.
Introduction: This study was performed to assess the relationship between tumour response and radiation dose in equivalent 2 Gy per fraction (EQD2).
Method: A retrospective cohort analysis of 21 patients with a diagnosis of intracranial haemangiopericytoma between 2000 and 2013 was included in this study. A total of 39 lesions were analysed. Read More
Virchows Arch 2018 May 7. Epub 2018 May 7.
Department of Pathology and Clinical Laboratories, Nagoya University Hospital, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8560, Japan.
Sinonasal glomangiopericytoma (SN-GPC) is an uncommon mesenchymal tumor with myoid differentiation. Recently, mutations in exon 3 of the gene coding for β-catenin (CTNNB1) and its nuclear expression were discovered in SN-GPC. β-catenin protein is a key regulatory molecule of the canonical Wnt signaling pathway. Read More