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Neurosurg Focus 2021 May;50(5):E22

Objective: Tumorous lesions of the spinal cord, as well as some vascular lesions like cavernous hemangiomas, demand careful consideration as to the indication and approach for surgery. As these lesions are rare in any departmental series, refinement of treatment strategies evolves over long periods. In this context, the authors evaluated a series of 500 intramedullary lesions for approach, technique, outcome, complications, and follow-up. Read More

Cureus 2021 Mar 26;13(3):e14128. Epub 2021 Mar 26.

Department of Neurosurgery, Cerrahpasa Medical Faculty, Istanbul University-Cerrahpasa, İstanbul, TUR.

Secondary parkinsonism is defined with some symptoms similar to idiopathic Parkinson's disease, but with different etiologies. And cerebral cavernous hemangioma is one of the rare cases. A 51-year-old, male patient was consulted with tremor, rigidity and bradykinesia on the right upper extremity. Read More

J Neurosci Rural Pract 2021 Apr 12;12(2):267-272. Epub 2020 Nov 12.

Department of Neurosurgery, Medical Faculty, Istanbul University-Cerrahpasa, Istanbul, Turkey.

 Cavernomas are usually found in the supratentorial area, and epileptic seizures are one of the presenting symptoms.  This study aims to provide the seizure outcome in adult patients who underwent surgical excision of single supratentorial cavernomas.  A total of 23 patients with single supratentorial cavernomas were operated between May 2011 and January 2019. Read More

World Neurosurg 2021 Apr 26. Epub 2021 Apr 26.

Department of Neurosurgery, University Hospital Münster, Münster, Germany.

Objective: Stand-alone minimally-invasive approaches for surgical management of spinal dumbbell tumors carry the risk of incomplete resections and impaired hemostasis. More extensive approaches require subsequent instrumentation with metal artifacts impairing follow-up imaging. Here, we present a technical note on percutaneous instrumentation using carbon fiber reinforced polyetheretherketone (CFR-PEEK) hardware combined with a minimally-invasive posterolateral approach for tumor resection. Read More

HGG Adv 2021 Apr 1;2(2). Epub 2021 Mar 1.

Department of Dermatology, School of Medicine, Yale University, New Haven, CT 06510, USA.

The term "cavernous hemangioma" has been used to describe vascular anomalies with histology featuring dilated vascular spaces, vessel walls consisting mainly of fibrous stromal bands lined by a layer of flattened endothelial cells, and an irregular outer rim of interrupted smooth muscle cells. Hepatic hemangiomas (HHs) and cutaneous venous malformations (VMs) share this histologic pattern, and we examined lesions in both tissues to identify genetic drivers. Paired whole-exome sequencing (WES) of lesional tissue and normal liver in HH subjects revealed a recurrent c. Read More

Radiol Case Rep 2021 Jun 17;16(6):1518-1523. Epub 2021 Apr 17.

Body Imaging, Radiology Department, IBERORAD, Barcelona, Spain.

We report a case of hepatic hemangiomatosis coexistent with a giant hepatic hemangioma diagnosed in the context of the study for SARS-CoV-2 infection. Computed tomography showed irregular contours of the left hepatic lobe with a lesion that compromised the whole lobe, with peripheral uptake and a centripetal tendency in the late phase, compatible with bulky cavernous hemangioma, as well as another lesion with the same characteristics in segment VI. Magnetic resonance imaging of the abdomen showed multiple hepatic hemangiomas observed in both lobes involving all segments, some of them smaller than 1 cm, which were hyperintense in the T2-weighted sequences and showed progressive contrast enhancement. Read More

BMC Surg 2021 Apr 26;21(1):210. Epub 2021 Apr 26.

Department of Urology, Affiliated Jinhua Hospital, Zhejiang University School of Medicine, Jinhua, 321000, China.

Background: Adrenal hemangioma is a rare benign adrenal tumor that is usually misdiagnosed preoperatively. We here present a case of adrenal cavernous hemangioma that was successfully treated with retroperitoneal laparoscopic adrenalectomy.

Case Presentation: A 67-year-old man with dull right back pain attended our clinic for examination of a mass on the right adrenal gland for 1 week. Read More

Braz J Otorhinolaryngol 2021 Mar 26. Epub 2021 Mar 26.

Sant'Andrea Hospital, NESMOS Department, Medicine and Psychology, ENT Clinic, Rome, Italy; Sant'Andrea University Hospital, NESMOS Department, Otolaryngology Clinic, Rome, Italy. Electronic address:

Secretory otitis media causes aural fullness and hearing loss secondary to Eustachian tube obstruction or incomplete resolution of acute otitis media. Every patient with unilateral middle ear effusion should undergo nasopharyngoscopy to assess the nasopharyngeal space. Expansive lesions at the level of pterygopalatine fossa may cause Eustachian tube compression with tube dysfunction with clinical findings of recurrent unilateral secretory otitis media. Read More

Indian J Pathol Microbiol 2021 Apr-Jun;64(2):334-338

Tatva Dental Clinic, Hyderabad, Telangana, India.

Intraosseous hemangiomas are uncommon, constituting less than 1% of all osseous tumors. The most frequent sites are the calvaria and the vertebral column. The involvement of the facial bones is rare, and if occurs, it can involve maxilla, mandible, nasal bones and zygomatic bone. Read More

Int J Surg Case Rep 2021 Apr 1;82:105844. Epub 2021 Apr 1.

University of Health Sciences Sisli Hamidiye Etfal Training and Research Hospital, Turkey. Electronic address:

Testicular hemangioma is a rare benign testicular tumor. In this case we presented who an infant applied to our clinic with left scrotal swelling. The tests performed were found to be compatible with testicular hemangioma and accompanying hydrocele. Read More

Ear Nose Throat J 2021 Apr 13:1455613211009132. Epub 2021 Apr 13.

460280The Vascular Birthmark Foundation, Latham, NY, USA.

Kyobu Geka 2021 Mar;74(3):237-240

Department of Thoracic and Cardiovascular Surgery, Osaka Medical College, Takatsuki, Japan.

A 66-year-old male with hypertension was referred for evaluation of abnormal find chest X-ray. A computed tomography (CT) scan revealed a solitary pericardial mass with a diameter of 5 cm, located in the left atrioventricular groove. It showed solid but unevenly enhanced contents suggesting a well vascularized tumor originating in either a part of the left heart or the pericardium. Read More

J Zoo Wildl Med 2021 Apr;52(1):332-336

College of Veterinary Medicine, University of Illinois at Urbana-Champaign, Urbana, IL 61802, USA,

Giraffes () are commonly managed in zoos and conservation programs worldwide, but the current understanding of the occurrence and progression of neoplastic disease in this species is limited by the scarcity of published reports. This study collated documented cases of neoplasia on the basis of gross and histologic evaluation of ante- and postmortem samples. In total, 30 giraffes from 22 institutions across the United States were included. Read More

Yeungnam Univ J Med 2021 Apr 7. Epub 2021 Apr 7.

Department of Surgery, Biomedical Research Institute and Pusan National University Hospital, Pusan National University School of Medicine, Busan, Korea.

Hepatic hemangiomas infrequently exhibit atypical imaging features, which may cause diagnostic confusion with hepatic malignancies and lead to unnecessary surgery. We report a rare case of multilocular cystic hemangioma of the liver mimicking a mucinous cystic neoplasm of the liver in a 48-year-old female, focusing on computed tomography and magnetic resonance imaging features and their differential diagnosis. Read More

Am J Blood Res 2021 15;11(1):72-76. Epub 2021 Feb 15.

Department of Orthopedics, School of Medicine, Isfahan University of Medical Sciences Isfahan, Iran.

Hemangiomas are benign soft tissue tumors that may be found everywhere in the human body. As one of the hemangioma types, cavernous hemangioma consists of a flat endothelium along with blood-filled spaces and may be found in the central nervous system, but rarely occurs in peripheral nerves. This article pertains to the introduction of an old female patient complaining of pain and paresthesia of the ulnar side of the left forearm and hypothenar with numbness and tingling of the fourth and fifth digits and clawing. Read More

Semin Ophthalmol 2021 May 31;36(4):232-240. Epub 2021 Mar 31.

Ophthalmic Plastic Surgery Service, Department of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, MA, USA.

Historically, surgical access to orbital tumors has required a transcutaneous, transconjunctival or transcranial approach. Resection of orbital tumors is notoriously challenging due to the surrounding dense network of critical structures in a confined bony cavity. Advances in endoscopic endonasal surgery, initially used for sinonasal and skull base conditions, have allowed for expansion of its applications beyond the sinorbital interface. Read More

Orbit 2021 Mar 29:1-4. Epub 2021 Mar 29.

Department of Ophthalmology & Vision Sciences, University of Toronto, Toronto, Canada.

Gaze-evoked amaurosis is a transient monocular vision loss elicited by eccentric gaze and has been reported in many orbital conditions but is most classically associated with intraconal tumors, such as cavernous hemangioma and optic nerve sheath meningioma. Here, the authors report a case of gaze-evoked amaurosis due to idiopathic orbital inflammation. The patient was a 35-year-old man who presented with vision loss only when abducting his left eye. Read More

J Neurol Surg B Skull Base 2021 Feb 19;82(1):20-26. Epub 2021 Jan 19.

Department of Otolaryngology-Head and Neck Surgery, Mayo Clinic, Rochester, Minnesota, United States.

Orbital hemangiomas are the most common primary neoplasm of the orbit and manifest as two distinct pathologic entities: infantile hemangiomas and cavernous hemangiomas. In this article, both infantile and cavernous hemangiomas are reviewed, with special attention paid to the natural history, clinical presentation, and management teams and approaches involved. An example case of each type of hemangioma is presented along with pearls and tips a reader can take away after reading this article. Read More

Am J Case Rep 2021 Mar 28;22:e929618. Epub 2021 Mar 28.

Department of Internal Medicine, São Paulo State University (Unesp), Medical School, Botucatu, SP, Brazil.

BACKGROUND Hemangiomas are benign vascular neoplasms that originate from fast-growing embryonic mesodermal tissue and have a proliferation of endothelial cells, which manifest themselves in different forms, locations, and dimensions. Owing to its rarity and similarity of symptoms with other chronic bowel diseases, intestinal hemangioma is a differential diagnosis to be considered in patients presenting with symptoms such as abdominal pain and anemia. CASE REPORT A 46-year-old woman with a history of diffuse abdominal pain and abdominal distension for 20 years presented with a worsening of symptoms in the past year. Read More

Int J Surg Case Rep 2021 Apr 23;81:105817. Epub 2021 Mar 23.

Department of General Surgery, Colorectal Surgery Section, King Fahad Specialist Hospital-Dammam, Dammam, Saudi Arabia.

Introduction: Hepatic cavernous hemangioma (HCH) is a common benign lesion of the liver. The radiological features of HCH can resemble those of hepatic malignancies such as metastatic liver cancer, which make the preoperative definitive diagnosis difficult.

Presentation Of Case: We report the case of a 77-year-old woman who presented with a 2-month history of abdominal pain and per rectum fresh bleeding. Read More

Neurochirurgie 2021 Mar 23. Epub 2021 Mar 23.

Department of neurosurgery, Imam Khomeini hospital, Tehran University of medical sciences, Keshavarz boulevard, Tehran, Iran.

Background: Cerebral cavernous malformation (CCM) in third ventricular area may become symptomatic relatively rarely, secondary to hemorrhage and growth or rupture into the ventricle, causing obstructive hydrocephalus, during third trimester of pregnancy.

Case Description: A 34 weeks pregnant (G4P1A2) lady was admitted to one of our satellite hospitals with one-week history of severe headache, blurred vision, nausea, vomiting, and right-sided facial numbness. At presentation, she had sudden decreased level of consciousness with Glasgow Coma Scale (GCS) equal to 4, and bilateral fixed pupils. Read More

Spinal Cord Ser Cases 2021 Mar 19;7(1):21. Epub 2021 Mar 19.

Department of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA.

Introduction: Intradural extramedullary capillary hemangiomas of the cauda equina are exceedingly rare, with only 20 previous cases reported. In the adult population, these tumors are rare and can arise in the central and peripheral nervous systems from the dura or spinal nerve roots. Intradural capillary hemangiomas of the cauda equina can yield symptoms such as lower extremity weakness, pain, and bladder and bowel dysfunction. Read More

JAMA Ophthalmol 2021 Mar 17;139(3):e204104. Epub 2021 Mar 17.

Department of Ophthalmology, Weill Cornell Medical College, New York, New York.

BMJ Case Rep 2021 Mar 9;14(3). Epub 2021 Mar 9.

Department of Surgical Gastroenterology, Jaslok Hospital and Research Centre, Mumbai, Maharashtra, India.

Haemangiomas of the small bowel are a very rare entity and rarely considered as an aetiology for an intestinal obstruction. Contrast-enhanced CT is the investigation of choice but the lesion can be confused with malignancy or rarely a neuroendocrine tumour. Commonly it presents as abdominal pain with anaemia and/or melaena. Read More

Radiol Case Rep 2021 May 24;16(5):1023-1027. Epub 2021 Feb 24.

Department of Gastroenterology, Hepatology, Tokyo Medical University, Shinjuku-ku, Tokyo, Japan.

Mediastinal cavernous hemangioma is a rare lesion requiring diagnosis without invasive procedure due to the risk of hemorrhage, which can be massive and even fatal. Here we describe the successful diagnosis of such a lesion using technetium-99m diethylenetriamine penta-acetic acid human serum albumin (Tc-HSA-D) scintigraphy. A 36-year-old female with a 3-week back pain underwent endoscopic ultrasonography, contrast-enhanced CT, and MRI dynamic study which together revealed a submucosal tumor of the esophagus; likely to be either hemangioma or lymphangioma. Read More

J Invest Surg 2021 Mar 4. Epub 2021 Mar 4.

Faculty of Dentistry Ain Shams University, Cairo, Egypt.

Surg Neurol Int 2021 17;12:58. Epub 2021 Feb 17.

Department of Neurosurgery, Cairo University School of Medicine and Teaching Hospitals, Manial, Cairo, Egypt.

Background: Extra-axial cerebral cavernous hemangiomas particularly those found in the sellar region, are extremely rare. Their clinical manifestations and imaging characteristics can mimic those of a pituitary adenoma thus making preoperative diagnosis difficult. Few cases are reported in the literature. Read More

Indian J Nucl Med 2020 Oct-Dec;35(4):360-361. Epub 2020 Oct 21.

Department of Nuclear Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

Hemangiomas are extremely rare tumors of the heart that may present with pericardial effusion, dyspnea, chest discomfort, palpitations, or syncope. Few published reports have highlighted the utility of F-fluorodeoxyglucose positron emission tomography-computed tomography (F-FDG PET-CT) in the evaluation of cardiac lesions. We report a case demonstrating the utility of F-FDG PET-CT in a young man who presented with gross pericardial effusion and suspicion of metastatic carcinoma on fluid cytology. Read More

World Neurosurg 2021 Feb 25. Epub 2021 Feb 25.

Department of Neurosurgery, Hospital of the University of Pennsylvania, Penn Medicine, Philadelphia, Pennsylvania, USA. Electronic address:

Objective: The surgical decision-making process for cavernous malformation (CM) must weigh the risks of surgery against the burden of patient symptoms/hemorrhage and anticipated natural history. Here, we sought to internally validate an International Classification of Disease (ICD)-10 search algorithm for CM surgery to use to analyze a nationwide administrative database.

Methods: Institutional records were accessed to test the validity of a novel ICD-10 search algorithm for CM surgery. Read More