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Pan Afr Med J 2022 15;41:214. Epub 2022 Mar 15.

Department of Child Health Nursing, Srimati Radhikabai Meghe Memorial College of Nursing, Datta Meghe Institute of Medical Sciences, Sawangi, Wardha, Maharashtra, India.

J Gastrointest Surg 2022 Jun 15. Epub 2022 Jun 15.

Department of Surgery, The Ohio State University Wexner Medical Center, 395 W. 12th Ave., Suite 670, Columbus, OH, USA.

Background: Hepatic hemangiomas (HHs) are benign liver lesions often discovered incidentally on imaging for various unrelated pathologies. We herein review the etiology, classification, diagnostic imaging, and management of HHs.

Methods: A comprehensive systematic review was performed utilizing MEDLINE/PubMed and Web of Science databases, with the end of search date being March 1, 2022, regarding HH diagnosis, imaging, and management. Read More

Case Rep Ophthalmol 2022 May-Aug;13(2):323-329. Epub 2022 May 2.

Institute for Vision Research, University of Iowa, Iowa City, Iowa, USA.

Von Hippel-Lindau (VHL) disease is a rare inherited cancer syndrome that results in the development of tumor formation in multiple systems. In the eye, retinal capillary hemangioma (RCH) can lead to severe vision loss. Retinopathy of prematurity (ROP) is likewise a rare disease in which abnormal retinal vasculature develops in premature infants. Read More

Pediatr Neurosurg 2022 Jun 13. Epub 2022 Jun 13.

Kaposiform hemangioendotheliomas (KHE) are rare vascular neoplasms composed of groups of capillaries and endothelial cells, forming aneurysms and arteriovenous fistulas. They occur mainly in the extremities during early childhood or infancy, and although they are locally aggressive, the occurrence of metastases is uncommon. A 9-month-old male infant born with a thoracolumbar cutaneous red lesion presented with progressive loss of strength in lower limbs, evolving with progressive flaccid paraplegia and areflexia. Read More

BMC Ophthalmol 2022 Jun 9;22(1):260. Epub 2022 Jun 9.

Department of Ophthalmology, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, 100045, China.

Background: Sturge-Weber Syndrome (SWS) is a rare disease involving the eye, skin, and brain. Port-wine stain (PWS) and glaucoma are common clinical manifestations. This study analysed the clinical characteristics of infants with PWS and glaucoma secondary to SWS. Read More

J Oral Pathol Med 2022 Jun 6. Epub 2022 Jun 6.

Unité de Dermatologie Pédiatrique et Centre de Référence des Maladies Rares de la Peau d'Origine Génétique, Hôpital Pellegrin-Enfants, CHU de Bordeaux, Bordeaux cedex, France.

Depending on impairment, treatment of vascular anomalies is decided on a case-by-case basis in pluridisciplinary consultations. Interventional treatments, especially surgery and sclerotherapy, are usually partially efficient and management of patients with vascular anomalies increasingly involves the use of medical drugs. The most common vascular tumor is infantile hemangioma where first-line medical treatment, when necessary, is propranolol. Read More

Pediatr Dev Pathol 2022 Jun 4:10935266221106910. Epub 2022 Jun 4.

Department of Neonatology, 2569Cleveland Clinic, Cleveland, OH, USA.

Angiomyxoma of the umbilical cord is a rare benign vascular malformation with potential for fetal morbidity and mortality. Gross and histologic features of this lesion are identical to those described as "hemangioma," however "angiomyxoma" is a preferable term as current practice restricts the term "hemangioma" to infantile capillary proliferations that express glucose transporter 1. Here we describe the case of an umbilical cord angiomyxoma with associated pseudocysts diagnosed after delivery at 33 weeks. Read More

NMC Case Rep J 2022 21;9:77-82. Epub 2022 Apr 21.

Department of Neurosurgery, Ichinomiya Municipal Hospital, Ichinomiya, Aichi, Japan.

Here we report a rare case of capillary hemangioma (CH) in a 28-year-old woman suffering from gradual worsening diplopia at 28 weeks of pregnancy. Magnetic resonance imaging (MRI) showed a mass lesion (about 3 cm in diameter) in the right parasellar region. We decided to observe as she was pregnant, and had no symptoms other than right abducent nerve palsy. Read More

Clin Res Hepatol Gastroenterol 2022 May 27:101962. Epub 2022 May 27.

Department of General Surgery, The First Affiliated Hospital of Soochow University, Suzhou 215006, China. Electronic address:

Background: Camrelizumab, as a PD-1 inhibitor on the market recently, presents favorable therapeutic efficacy in several advanced cancers, while its application in metastatic gastric cancer (mGC) lacks data. This study aimed to assess treatment response, survival profile, and adverse events of camrelizumab plus apatinib regimen as third-line treatment in mGC patients.

Methods: Nineteen mGC patients who received camrelizumab plus apatinib as third-line treatment were analyzed in this observational study. Read More

Int J Surg Pathol 2022 May 29:10668969221101867. Epub 2022 May 29.

91854Douglass Hanly Moir Pathology, Sonic Healthcare, Macquarie Park, Australia.

Epithelioid hemangioma is a benign vascular neoplasm associated with FOS and/or FOSB protein overexpression detected by immunohistochemistry (IHC). The aim of our study was to determine the co-expression or independent IHC expression of FOS and FOSB in a cohort of epithelioid hemangiomas. We also included two cohorts of other vascular lesions: papillary endothelial hyperplasia and lobular capillary hemangioma / pyogenic granuloma. Read More

BMC Ophthalmol 2022 May 23;22(1):232. Epub 2022 May 23.

Department of Ophthalmology, College of Medicine, King Saud University, P.O. Box 245, Riyadh, 11411, Saudi Arabia.

Background: Intramuscular haemangiomas are rare, benign vascular tumours that represent < 1% of all haemangiomas. When involving the extraocular muscles, haemangiomas are extremely rare, with only nine cases reported in the literature; to date there are no reported cases of extraocular muscle haemangiomas extending into the brain.

Case Presentation: A 6-year-old boy with a two-week history of a painless swelling and erythema on the upper eyelid. Read More

Hand Surg Rehabil 2022 May 13. Epub 2022 May 13.

Department of Orthopedics and Traumatology, Cliniques Universitaires de Bruxelles, Hôpital Erasme, Université libre de Bruxelles, 808 Lennik str., 1070 Bruxelles, Belgium.

Pediatric cases of post-traumatic hemangioma of the palm are rare. Clinical evaluation and imaging are sometimes ambiguous and surgical exploration may show more conclusive results. This case report discusses the diagnosis and treatment of a teenager with post-traumatic hemangioma infiltrating the flexor digitorum profundus tendon of the index finger. Read More

Int J Environ Res Public Health 2022 05 5;19(9). Epub 2022 May 5.

Shaanxi Key Laboratory of Ultrasound, School of Physics and Information Technology, Shaanxi Normal University, Xi'an 710062, China.

The development of appropriate photothermal detection of skin diseases to meet complex clinical demands is an urgent challenge for the prevention and therapy of skin cancer. An extensive body of literature has ignored all high-order harmonics above the second order and their influences on low-order harmonics. In this paper, a new iterative numerical method is developed for solving the nonlinear thermal diffusion equation to improve nonlinear photothermal detection for the noninvasive assessment of the thickness of port-wine stain (PWS). Read More

J Dermatol 2022 May 13. Epub 2022 May 13.

Department of Dermatology, Japanese Red Cross Saitama Hospital, Saitama, Japan.

Ophthalmol Retina 2022 May;6(5):410

Sankara Eye Hospital, Bangalore, India.

BMC Ophthalmol 2022 May 6;22(1):205. Epub 2022 May 6.

Department of Ophthalmology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450000, China.

Background: To report the multimodal imaging and treatment of fifteen retinal capillary hemangioblastomas (RCHs) associated with Von Hippel-Lindau syndrome in a monocular patient during a long-term following-up, which supply high-resolution exquisite SS-OCTA images (VG200; SVision Imaging, Ltd., Luoyang, China) and management experience about multiple RCHs.

Case Presentation: A 34-year-old monocular male patient complained decreased visual acuity (20/100) without pain and redness in the left eye five years ago. Read More

J Pharmacol Sci 2022 Jun 26;149(2):60-65. Epub 2022 Mar 26.

Department of Pharmacy Practice & Science, School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan.

Infantile hemangioma (IH) is a common tumor in infants that gradually resolves and is often untreated. However, for cosmetic reasons, parents often opt for treatment. Oral propranolol, the first-line therapy for IH, is sometimes associated with several side effects, including hypotension, bradycardia, and hypoglycemia. Read More

Int Med Case Rep J 2022 26;15:225-230. Epub 2022 Apr 26.

Department of Obstetrics and Gynecology, Panzi General Referral Hospital, Bukavu, The Democratic Republic of Congo.

We report an unusual case of female genital fistula secondary to a lobular capillary hemangioma. A 35-year-old Congolese woman presented with urinary incontinence associated with a vaginal "tearing" sensation during micturition. A suburethral vascular bud and vesico-vaginal fistula were observed on examination. Read More

Radiol Case Rep 2022 Jun 19;17(6):2211-2214. Epub 2022 Apr 19.

School of Medicine, University of Queensland, Herston, QLD 4006 Australia.

We present a case of a 65-year-old male with a biopsy proven subcutaneous capillary haemangioma identified on imaging for evaluation of further metastatic spread of prostatic carcinoma due to a rise in his prostate-specific antigen biochemistry. He was receiving salvage radiation therapy for his known isolated nodal disease, four years after prostatectomy. An intensely avid prostate-specific membrane antigen positron emission tomography-computed tomography lesion in the left paramedian back at the level of L1 was noted on his scan. Read More

J Vasc Surg Cases Innov Tech 2022 Jun 31;8(2):237-239. Epub 2022 Mar 31.

Integrated Pathology Services, Bridgetown, Barbados.

Lobular capillary hemangiomas (LCHs) are a common form of benign vascular tumors originating from the skin and subcutaneous tissues. We have described the case of a 47-year-old man who had presented with a 1-month history of a tender swelling to the right temporal region. Biopsy was performed to rule out temporal arteritis and demonstrated a subset of LCH, now formally known as intravascular LCH. Read More

Vestn Oftalmol 2022 ;138(2):66-78

Research Institute of Eye Diseases, Moscow, Russia.

The article presents five cases of various forms of hemangiomas of the optic nerve head (ONH) and juxtapapillary retina that were monitored and analyzed using ocular visualization methods. The obtained data allowed a conclusion that capillary hemangioma of the ONH features clearly-seen boundaries of the lesion both on ophthalmoscopy and optical coherence tomography (OCT) images; on the other hand, juxtapapillary granuloma can be characterized by blurred outlines on ophthalmoscopy and a gradual transition of the altered retina on OCT images with secondary changes seen in the macular area. When comorbid, capillary hemangioma of the ONH and retina feature a combination of these visualization signs. Read More

Neurochirurgie 2022 Apr 25. Epub 2022 Apr 25.

Department of Neurosurgery, GHU site Sainte-Anne, Paris, France; Université de Paris, 102-108 rue de la Santé, 75014 Paris, France; Institut de Psychiatrie et Neurosciences de Paris (IPNP), UMR S1266, Inserm, IMA-BRAIN, Paris, France. Electronic address:

Background: Spinal hemangiomas are rare vascular malformations resulting from proliferation of vascular endothelial cells. The cavernous form is the most common and represents 5-12% of spinal vascular malformations, while the capillary form is rare.

Case Description: A 56-year-old patient with no past medical history presented with progressive spinal cord compression symptoms localizing to the T10 level with MRC grade 4 proximal paraparesis. Read More

Klin Monbl Augenheilkd 2022 04 26;239(4):548-551. Epub 2022 Apr 26.

Department of Ophthalmology, Cantonal Hospital St. Gallen, St. Gallen, Switzerland.

Dermatopathology (Basel) 2022 Mar 25;9(2):94-99. Epub 2022 Mar 25.

Department of Dermatology, Graduate School of Medicine, Mie University, 2-174 Edobashi, Tsu 514-8507, Mie, Japan.

Eccrine angiomatous hamartoma (EAH) is a relatively rare benign skin disease characterized by the proliferation of eccrine sweat glands associated with capillary hemangioma and the proliferation of other skin elements such as adipose tissue, hair, and epidermis. The onset of the disease is usually at birth or in childhood and tends to occur in the extremities of females, but it occurred in an adult male in this case. The patient was a 72-year-old man with a 12 × 12 mm light brown, elastic, slightly firm skin nodule on the flexor aspect of his right forearm. Read More

Eur J Paediatr Neurol 2022 May 13;38:66-72. Epub 2022 Apr 13.

Department of Neuroradiology, ErasmusMC- Sophia Children's Hospital, Rotterdam, the Netherlands.

Background: Patients with Sturge-Weber syndrome type 1 (SWS1) have a port-wine birthmark (PWB) as cutaneous hallmark. Up to 35% of neonates with a high risk PWB develop SWS1. Clinical manifestations are severe and often progressive. Read More

J Oral Maxillofac Pathol 2022 Feb 28;26(Suppl 1):S119-S123. Epub 2022 Feb 28.

Department of Maxillofacial Surgery and Diagnostic Science, College Dentistry, King Saud Bin Abdulaziz University for Health Science, King Abdullah International Medical Research Center, King Saud University, Riyadh, Saudi Arabia.

Pyogenic granuloma (PG) is a benign nonneoplastic mucocutaneous lesion. It occurs as a result of chronic irritation or due to hormonal changes. The most favorable site for this fairly common lesion is gingiva, but rarely, it can occur outside the oral cavity, later often difficult to diagnose, as a diverse group of the pathologic process can produce such lesions outside the oral cavity. Read More

Eur J Breast Health 2022 Apr 1;18(2):190-194. Epub 2022 Apr 1.

Department of Radiology, Ege University Faculty of Medicine, İzmir, Turkey.

Vascular tumors are rare in the breasts, and the most common forms include hemangiomas and angiosarcomas. Hemangiomas are rare benign vascular tumors. Most of them are asymptomatic and nonpalpable clinically, and the vast majority of such lesions are detected incidentally by mammography. Read More

Cureus 2022 Mar 15;14(3):e23166. Epub 2022 Mar 15.

Department of Neurosurgery, King Abdulaziz Medical City, Riyadh, SAU.

Hemangiomas are nonmalignant vascular lesions commonly seen in both the skin and mucosa that rarely occur in skeletal muscles. According to the type of vessel, a hemangioma can be differentiated into capillary, cavernous, or mixed types. The following report describes a case of temporalis muscle hemangioma in a 45-year-old female who presented with painful swelling in the left outer orbital wall, which had been growing in size over the past 12 months. Read More

BMJ Case Rep 2022 Apr 20;15(4). Epub 2022 Apr 20.

Aravind Eye Hospital, Madurai, India.

Congenital retinal macrovessel (CRM) is defined as a large aberrant blood vessel that traverses through the central macula. It can have large tributaries extending on both sides of the horizontal raphe. The condition is typically asymptomatic. Read More

Abdom Radiol (NY) 2022 Jun 15;47(6):1961-1967. Epub 2022 Apr 15.

Department of Radiology, Faculty of Medicine, Saga University, 5-1-1 Nabeshima, Saga, 849-8501, Japan.

We report a case of congenital capillary proliferation of the kidney (CCPK) along with the multimodality imaging findings. Four-day-old boy who had managed due to his mother's gestational diabetes underwent abdominal ultrasound and a mass was detected in the right kidney. On gray scale ultrasound, the mass exhibited a hyperechoic, slight lobulated shape and a circumscribed margin. Read More