2,174 results match your criteria Hemangioblastoma
Cureus 2018 Sep 28;10(9):e3380. Epub 2018 Sep 28.
Neurosurgery, The Icahn School of Medicine at Mount Sinai, New York, USA.
Hemangioblastomas are rare, slow-growing, highly vascularized tumors of the central nervous system which often occur in the spinal cord. When presenting as sporadic, isolated tumors without Von-Hippel Lindau disease, they are curable through surgery with a low rate of recurrence. Tumor recurrence in these cases is usually associated with prior subtotal resection. Read More
J Neurosurg 2018 Oct 1:1-9. Epub 2018 Oct 1.
OBJECTIVEVon Hippel-Lindau disease (VHL) is a tumor predisposition syndrome characterized by CNS hemangioblastomas (HBs) and clear cell renal cell carcinomas (RCCs) due to hypoxia-inducible factor activation (pseudohypoxia). Because of the lack of effective medical therapies for VHL, HBs and RCCs account for significant morbidity and mortality, ultimately necessitating numerous neurological and renal surgeries. Propranolol is an FDA-approved pan-beta adrenergic antagonist with antitumor effects against infantile hemangiomas (IHs) and possibly VHL HBs. Read More
BMC Med Genet 2018 Nov 26;19(1):204. Epub 2018 Nov 26.
Department of Ophthalmology, Chinese PLA General Hospital, Beijing, 100853, China.
Background: Von Hippel-Lindau (VHL) disease is an autosomal dominant inherited cancer syndrome, and VHL is identified as a tumor suppressor gene. The main objective of this study was to identify disease-causing mutations in a Chinese family affected with VHL disease.
Methods: Genomic DNA was extracted from peripheral blood from a Chinese family with VHL. Read More
J Spinal Cord Med 2018 Nov 26:1-4. Epub 2018 Nov 26.
a Department of Neurosurgery , The Second Affiliated Hospital of Nanchang University , Nanchang , People's Republic of China.
Context: Cases of migratory spinal tumors have been reported since 1963. Most involve spinal schwannomas, which are benign tumors of the lining of nerve cells. We report a rare case of a mobile spinal hemangioblastoma, which is a type of benign vascular tumor. Read More
Lancet Oncol 2018 Nov 22. Epub 2018 Nov 22.
Department of Neurosurgery, Laura and Isaac Perlmutter Cancer Center, NYU Langone Health System, New York University, New York, NY, USA. Electronic address:
Background: A major concern of patients who have stereotactic radiosurgery is the long-term risk of having a secondary intracranial malignancy or, in the case of patients with benign tumours treated with the technique, the risk of malignant transformation. The incidence of stereotactic radiosurgery-associated intracranial malignancy remains unknown; therefore, our aim was to estimate it in a population-based study to assess the long-term safety of this technique.
Methods: We did a population-based, multicentre, cohort study at five international radiosurgery centres (Na Homolce Hospital, Prague, Czech Republic [n=2655 patients]; Ruber International Hospital, Madrid, Spain [n=1080], University of Pittsburgh Medical Center, Pittsburgh, PA, USA [n=1027]; University of Virginia, Charlottesville, VA, USA [n=80]; and NYU Langone Health System, New York, NY, USA [n=63]). Read More
J Neurol Surg B Skull Base 2018 Dec 25;79(Suppl 5):S422-S423. Epub 2018 Sep 25.
Department of Neurological Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, United States.
To demonstrate a rare complication of endovascular tumor embolization with onyx. Operative video. Department of neurological surgery in a university hospital. Read More
Medicine (Baltimore) 2018 Nov;97(46):e13179
Department of Neurosurgery, West China Hospital, Sichuan University.
Rationale: Cystic meningioma located at the cerebellopontine angle (CPA) is an extremely rare occurrence. It is frequently misdiagnosed preoperatively. Little is known about the clinical features and outcome of this rare disease. Read More
World Neurosurg 2018 Nov 4. Epub 2018 Nov 4.
Texas A&M College of Medicine, Temple, Texas, USA; Department of Neurosurgery, Baylor Scott & White Health, Temple, Texas, USA. Electronic address:
Background: Hemangioblastomas (HBMs) are benign vascular neoplasms that most commonly arise within the cerebellum. While other vascular lesions should be considered in the differential diagnosis, HBMs rarely resemble aneurysms on neuroimaging and only one case of a cerebellar HBM mimicking a posterior fossa aneurysm has been reported. Here we describe a retromedullary HBM that masqueraded as a distal posterior inferior cerebellar artery (PICA) medullary branch aneurysm. Read More
Cureus 2018 Aug 16;10(8):e3154. Epub 2018 Aug 16.
Neurosurgery, University of Miami Miller School of Medicine, Miami, USA.
Background Vascular lesions represent a rare subset of intramedullary spinal cord pathology and consist of cavernous malformations (CM), hemangioblastomas, and arteriovenous malformations (AVM). These lesions are each unique and the literature pertaining to their surgical management is largely limited to retrospective case series and case reports. Objectives To evaluate the surgical management of each of these lesions with special attention to postoperative functional status. Read More
NMC Case Rep J 2018 Oct 13;5(4):95-97. Epub 2018 Sep 13.
Department of Neurosurgery, Kurashiki Central Hospital, Kurashiki, Okayama, Japan.
The surgical removal of giant solid hemangioblastoma involves a high risk of perioperative bleeding and requires attentive hemostasis. Here, we present a case of a giant solid hemangioblastoma accompanied with hemophilia which was previously undiagnosed. A 35-year-old man without any past medical history was admitted with diplopia and ocular motility disorder. Read More
Surv Ophthalmol 2018 Oct 13. Epub 2018 Oct 13.
Sheffield Ocular Oncology Service, Royal Hallamshire Hospital, Sheffield, UK.
Optic nerve hemangioblastoma is a rare tumor that is usually unilateral and most commonly occurs in the context of von Hippel-Lindau disease. Differential diagnosis is based on clinical history and imaging. Magnetic resonance imaging with gadolinium enhancement is the most useful imaging modality as it can reveal flow voids and an absence of dural attachment, differentiating optic nerve hemangioblastoma from other more commonly encountered optic nerve tumors. Read More
Medicine (Baltimore) 2018 Oct;97(41):e12586
Department of Pathology, China-Japan Union Hospital of Jilin University.
Introduction: This study aims to investigate the pathological features of a patient with paraganglioma in the lumbar spinal canal.
Case Presentation: The patient was 36 years old male with electrical pain in the waist and buttock which occurred intermittently, and was not relieved under oral use of analgesics. Immunohistochemical staining was performed to diagnose the disease. Read More
Int J Retina Vitreous 2018 3;4:36. Epub 2018 Oct 3.
3Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, 840 Walnut Street, 14th Floor, Philadelphia, PA 19107 USA.
Background: To describe a case of von Hippel-Lindau disease with peripheral retinal nonperfusion.
Case Presentation: A 66-year-old female with known cerebellar and midbrain hemangioblastomas was evaluated for a retinal hemangioblastoma in the right eye. She underwent widefield fluorescein angiography, which showed hyperfluorescence localized to the hemangioblastoma surrounded by peripheral retinal nonperfusion in the same quadrant. Read More
World Neurosurg 2018 Oct 5. Epub 2018 Oct 5.
Department of Neurological Surgery, Goodman Campbell Brain and Spine and Indiana University, Indianapolis, Indiana, USA. Electronic address:
Background: Indocyanine green (ICG) videoangiography can assess cerebral blood flow, but results are primarily qualitative. FLOW 800 software measures fluorescence dynamics and creates a semiquantitative color delay map for assessment of relative sequence of blood flow within the vasculature.
Methods: We retrospectively reviewed 23 consecutive patients for whom FLOW 800 ICG videoangiography was used. Read More
J Clin Neurosci 2018 Dec 1;58:226-228. Epub 2018 Oct 1.
National Institute of Neurological Disorders and Stroke, Bethesda, MD, USA. Electronic address:
Low-pressure hydrocephalus (LPH) is a rare clinical diagnosis, characterized by neurologic decline and ventriculomegaly that persists despite normal to low intracranial pressure. LPH is typically managed by negative-pressure drainage via ventriculostomy, followed by low-resistance shunt insertion. We present the case of a middle-aged man with a history of hemangioblastomatosis who had spontaneous subarachnoid hemorrhage. Read More
Medicina (B Aires) 2018 ;78(5):305-310
División Neurocirugía, Instituto de Investigaciones Médicas Alfredo Lanari, Universidad de Buenos Aires, Argentina.
Brainstem tumors are uncommon beyond childhood. Controversies arise regarding the need of histological diagnosis in this eloquent area of the brain, weighting the benefits of a reliable diagnosis against the disadvantages of invasive procedures. There are scant publications about the surgical management of brainstem tumors in adults, all of them involving small retrospective cohorts. Read More
Medicine (Baltimore) 2018 Sep;97(39):e12477
School of Medicine, Texas Tech University Health Science Center, Lubbock, TX.
Rationale: Hemangioblastoma is a rare tumor of the central nervous system (CNS). It is usually observed in patients with von-Hippel Lindau (VHL). The peak age for hemangioblastoma is between 20 and 50 years of age with very few cases over 65 or below 18 years of age. Read More
Chin Med Sci J 2018 Sep;33(3):188-193
Department of Radiology, Chinese PLA General Hospital, Beijing 100853, China.
We performed contrast-enhanced T2 fluid-attenuated inversion recovery (T2-FLAIR) and dynamic contrast enhanced MRI to illustrate the imaging characteristics of one case of hemangioblastoma. T2-FLAIR showed a large cyst located in the right cerebellum with mural nodule. The intensely enhancing cyst wall was observed on enhanced T2-FLAIR images acquired from 5. Read More
J Clin Neurosci 2018 Nov 24;57:126-130. Epub 2018 Sep 24.
Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, People's Republic of China. Electronic address:
The study aims to assess the management and maternal and fetal outcomes of pregnancies complicated by central nervous system (CNS) hemangioblastoma. Twenty-four female patients with CNS hemangioblastoma, who were pregnant in a tumor-burden status, were identified. Their medical charts, treatments, and follow-up materials were carefully reviewed. Read More
Oncoscience 2018 Jul 22;5(7-8):212-213. Epub 2018 Aug 22.
Chi-Chao Chan: National Eye Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Nagoya J Med Sci 2018 Aug;80(3):431-434
Department of Neurosurgery, Sapporo Medical University School of Medicine, Sapporo, Japan.
Meningiomas rarely exhibit cystic lesions with mural nodules, and may be misdiagnosed as intraparenchymal cystic tumors. We herein present a 64-year-old woman with a cystic lesion and enhancing mural nodule in the left temporal lobe accompanied by peritumoral brain edema. Differential diagnoses included low-grade gliomas, hemangioblastoma, and cystic meningioma. Read More
J Med Case Rep 2018 Sep 6;12(1):248. Epub 2018 Sep 6.
Institute of Ophthalmology, Università Cattolica del Sacro Cuore, Fondazione Policlinico Universitario A. Gemelli - IRCCS, Rome, Italy.
Background: Von Hippel-Lindau disease is a rare hereditary syndrome caused by germinal mutations in a von Hippel-Lindau tumor-suppressing gene. Retinal hemangioblastoma is the ocular hallmark lesion of von Hippel-Lindau disease.
Case Presentation: A 20-year-old Caucasian woman presented to our institution with painless visual impairment in the right eye. Read More
J Int Med Res 2018 Sep 4:300060518792368. Epub 2018 Sep 4.
Department of Otolaryngology, People's Hospital of Peking University, Beijing, China.
Von Hippel-Lindau (VHL) syndrome is caused by germline mutations in the VHL gene and is accompanied by the development of both benign and malignant tumors. Clarithromycin (CAM) is a widely used anti-inflammatory drug that has also been proven effective for treating some cancers. In this study, we present a novel case of a 38-year-old female patient with VHL syndrome confirmed by computed tomography, with no relevant family history. Read More
Neurosurg Rev 2018 Aug 31. Epub 2018 Aug 31.
Sri Chitra Tirunal Institute for Medical Science and Technology, Medical college post, Trivandrum, Kerala, 691011, India.
Spinal hemangioblastomas constitute 1.6-5.8% of all spinal cord tumors. Read More
Intern Med 2018 Aug 24. Epub 2018 Aug 24.
Department of Respiratory Medicine, National Hospital Organization Okayama Medical Center, Japan.
Objective Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a minimally invasive procedure for pulmonary and mediastinal diseases. This study compared the performance of a novel 19-G needle with a 21- or 22-G needle. Patients and Methods Eleven patients at Okayama Medical Center were enrolled retrospectively between April and December 2017. Read More
Case Rep Endocrinol 2018 10;2018:8967159. Epub 2018 Jul 10.
Division of Endocrinology and Metabolism, Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA.
Von Hippel-Lindau (VHL) disease, caused by germline mutations in the gene, is characterized by metachronously occurring tumors including pheochromocytoma, renal cell carcinoma (RCC), and hemangioblastoma. Although VHL disease leads to reduced life expectancy, its diagnosis is often missed and tumor screening guidelines are sparse. VHL protein acts as a tumor suppressor by targeting hypoxia-inducible factors (HIFs) for degradation through an oxygen-dependent mechanism. Read More
J Neuroimaging 2018 Nov 1;28(6):656-665. Epub 2018 Aug 1.
Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA.
Background And Purpose: We aimed to develop a diagnostic algorithm for differentiation of cerebellar hemisphere tumors, combining Apparent Diffusion Coefficient (ADC) histogram analysis and structural imaging features.
Methods: Pretreatment MRI of patients with pathologically proven cerebellar hemisphere neoplasms were reviewed. Voxel-wise volumetric ADC histograms of tumor solid components were determined. Read More
Sci Rep 2018 Jul 24;8(1):11144. Epub 2018 Jul 24.
Department of Neurology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China.
Due to its rarity, current literature assessing prognostic factors and survival outcomes of hemangioblastoma is limited. Patients with histologically confirmed hemangioblastoma were identified from the US National Cancer Data Base. 1488 patients met inclusion criteria. Read More
Ophthalmology 2018 Aug 4;125(8):1188. Epub 2018 Jul 4.
Department of Ophthalmology, Ben Taub General Hospital, Houston, Texas.
Oper Neurosurg (Hagerstown) 2018 Jul 13. Epub 2018 Jul 13.
Department of Neurological Surgery, Neurological Institute, Case Western Reserve University, University Hospitals Cleveland Medical Center, Cleveland, Ohio.
This 3-dimensional operative video illustrates resection of a thoracic hemangioblastoma in a 30-year-old female with a history of Von Hippel-Lindau disease. The patient presented with right lower extremity numbness and flank pain. Magnetic resonance imaging (MRI) demonstrated an enhancing intradural intramedullary lesion at T 7 consistent with a hemangioblastoma. Read More
Am J Ophthalmol Case Rep 2018 Sep 2;11:61-63. Epub 2018 Jun 2.
Ophthalmology Department, Kasr Al Ainy School of Medicine, Cairo University, Egypt.
Purpose: To report a case of submacular cystic lesion that turned out to be a sclerosing capillary hemangioblastoma. The retinal capillary hemangioblastoma may arise as a part of von Hippel-Lindau syndrome however, they may occur as an isolated entity , but submacular capillary hemangioblastoma has never been reported.
Observations: A case of a 56-year-old female who presented with a right yellow submacular lesion. Read More
J Neurosurg Spine 2018 Oct 6;29(4):448-451. Epub 2018 Jul 6.
Neurosurgery Department, Universitair Ziekenhuis Brussel, Brussels, Belgium; and.
The surgical management of anteriorly located spinal cord hemangioblastomas remains a challenge. Different approaches have been published, of which the anterior approach seems to be the most obvious and commonly used. A posterior approach might be more suitable in certain patients, especially in cases of cystic hemangioblastomas. Read More
Zhongguo Yi Xue Ke Xue Yuan Xue Bao 2018 Jun;40(3):436-438
Department of Radiology,Hainan Branch of Chinese PLA General Hospital,Sanya,Hainan 572013,China.
We reported a case with epidermoid cyst (EC) in the fourth ventricle. The insinuation and scalloping growth pattern were the distinctive imaging characteristics of EC in the fourth ventricle on magnetic resonance imaging. The accurate identification of the punctate enhancement of vessels around the lesion may be helpful for its differential diagnosis from hemangioblastoma. Read More
Am J Ophthalmol Case Rep 2018 Sep 24;11:49-51. Epub 2018 May 24.
Weill-Cornell Medical Center, New York, NY, 10065, USA.
Purpose: To report on two cases of treatment-refractory juxtapapillary hemagioblastomas that were managed with intra-arterial bevacizumab delivered via the ophthalmic artery.
Observations: Case 1 is a 35 year-old man with juxtapapillary hemangioblastoma who continued to have progressive tractional retinal detachment, optic nerve neovascaularization and cystoid macula edema (CME) despite heavy prior treatment with intravitreal anti-vascular endothelial growth factor (VEGF) and steroid intravitreal injections and laser. Case 2 is a 41 year-old woman with juxtapapillary hemangioblastoma who had progressive tractional retinal detachment, CME and visually-threatening intraocular pressure elevation despite treatment with anti-VEGF injection and laser. Read More
Oncotarget 2018 Jun 15;9(46):28009-28015. Epub 2018 Jun 15.
National Skull Base Center, Thousand Oaks, California, USA.
Introduction: Intracranial hemangioblastoma (HB) is a rare pathology. Limited data exist regarding its epidemiology.
Methods: With the SEER-18 registry database, information from all patients diagnosed with intracranial HB from 2004 to 2013 were extracted, including age, gender, race, marital status, presence of surgery, extent of surgery, receipt of radiation, tumor size, tumor location, and follow-up data. Read More
Int J Womens Health 2018 21;10:325-328. Epub 2018 Jun 21.
Department of Gynecology and Obstetrics, University Hospital of Brasilia, University of Brasília, Brasília, Brazil.
Hemangioblastomas are benign tumors of the central nervous system (CNS) that may occur either sporadically or as part of von Hippel-Lindau (VHL) disease, in which they coexist with a series of other tumors outside the CNS. Because of their low mitosis rate, hemangioblastomas usually have slow-growing and late manifestations, but may cause sudden neurological symptoms if tumor hemorrhage occurs. Few studies have evaluated the impact of pregnancy on the evolution of hemangioblastomas. Read More
Cancer Biol Ther 2018 9;19(9):766-772. Epub 2018 Jul 9.
a Department of Urology , Institute of Surgery Research, Daping Hospital, Third Military Medical University , Chongqing 400042 , PR China.
Von Hippel-Landau (VHL) disease is characterized by malignant and benign tumors in multiple organs. Sunitinib, a tyrosine kinase inhibitor, has been clinically available for treating sporadic patients with recurrent or unresectable and metastatic clear renal cell carcinomas (cRCCs) and metastatic lesions of the lung, but its effect on VHL disease-associated tumors remains poorly understood. This retrospective case series examined the effect of sunitinib on RCC, hemangioblastomas, pheochromocytomas, and pancreatic neuroendocrine tumors in patients with confirmed VHL. Read More
Pathol Res Pract 2018 Aug 29;214(8):1156-1165. Epub 2018 May 29.
Lab Bacchi, Botucatu, SP, Brazil. Electronic address:
Less than 250 extraneuraxial hemangioblastomas occurring in paraneuraxial or peripheral sites have been reported to date, sporadically or in the setting of von Hippel-Lindau disease. Seventeen such cases underwent molecular genetic analysis, using either the patient's peripheral blood in 9 cases or paraffin embedded tumor tissue in the rest. VHL gene mutations were documented in 3/9 cases in which DNA from peripheral blood lymphocytes was used, all with clinically manifest von Hippel-Lindau disease; instead, no VHL gene alterations were found in all of the 8 cases with sporadic extraneuraxial hemangioblastoma in which DNA from tumor tissue was analyzed. Read More
Brain Tumor Pathol 2018 Jun 23. Epub 2018 Jun 23.
Department of Neurosurgery, Kyoto University Graduate School of Medicine, 54 Kawaharacho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan.
Hemangioblastoma is composed of neoplastic stromal cells and a prominent capillary network. To date, the identity of stromal cells remains unclear. Mesenchymal stem cells can give rise to committed vascular progenitor cells, and ephrin-B2/EphB4 and Notch signaling have crucial roles in these steps. Read More
Oman J Ophthalmol 2018 May-Aug;11(2):166-168
Department of Ophthalmology, Dr. RML Hospital, New Delhi, India.
Von Hipple-Lindua (VHL) syndrome is an autosomal dominant neoplastic disorder in which multiple benign or malignant tumours and cysts develop in central nervous system and visceral organs. Retinal capillary hemangioma is the most frequent and often the earliest manifestation of VHL syndrome. We report a case with multisystemic involvement diagnosed as a case of multiple endocrine neoplasia (MEN) syndrome but the presence of multiple, unilateral peripheral and juxtapapillary retinal capillary hemangioma was able to clinche the definative diagnosis of VHL and thus helped in appropriate management of the patient. Read More
J Kidney Cancer VHL 2018 6;5(2):1-6. Epub 2018 Jun 6.
Department of Neurosurgery, International University of Health and Welfare Atami Hospital, Atami, Japan.
Central nervous system hemangioblastomas are generally restricted to the cerebellum, spinal cord, and brainstem. Supratentorial hemangioblastomas are uncommon, and optic nerve hemangioblastomas are extremely rare, with fewer than 25 reports including this case. In this report, we present the case of a 36-year-old woman with von Hippel-Lindau (VHL) disease who presented with progressive diminution of vision in the left eye due to a retrobulbar optic nerve hemangioblastoma. Read More
World Neurosurg 2018 Sep 7;117:e187-e193. Epub 2018 Jun 7.
Department of Neurosurgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Objective: Hemangioblastomas (HBs) are benign vascular tumors of the central nervous system and histologically contain abundant microvessels. Therefore, they clinically exhibit vascular malformation-like characteristics. It has been described that endothelial-to-mesenchymal transition (EndMT) contributes to the pathogenesis of cerebral cavernous malformations. Read More
Neurosurg Focus 2018 Jun;44(6):E6
Neurosurgical Unit II, Department of Neurosurgery, Fondazione IRCCS "Istituto Neurologico Carlo Besta," Milan, Italy.
OBJECTIVE Indocyanine green videoangiography (ICG-VA) is an intraoperative technique used to highlight vessels in neurovascular surgery. Its application in the study of the vascular pathophysiology in CNS tumors and its role in their surgical management are still rather limited. A recent innovation of ICG-VA (i. Read More
Pol Merkur Lekarski 2018 May;44(263):248-252
Molecular Biology Unit, Department of Internal Diseases and Nephrodiabetology, Medical University of Lodz, University Clinical Hospital , Lodz, Poland.
Von Hippel-Lindau disease (vHL, familial cerebello-retinal angiomatosis) is a rare genetic autosomal dominant disorder associated with predisposition to vascular tumors. Mutations of VHL tumor suppressor gene, located on chromosome 3p25-26, are responsible for clinical manifestation of the disease. The VHL gene product encodes VHL protein, which is responsible for HIF-1 (hypoxia-inducible factor-1) dependent cell cycle regulation and cellular pathways mediated by VEGF, PDGF, TGF-α, EPO. Read More
Drug Metab Pers Ther 2018 09;33(3):127-134
Professor,Department of Neurosurgery, Amrita Institute of Medical Sciences and Research Centre, Kochi-41, Kerala, India.
J Neurosurg Spine 2018 Aug 25;29(2):220-225. Epub 2018 May 25.
Departments of 1 Radiation Oncology and.
OBJECTIVE Akin to the nonoperative management of benign intracranial tumors, stereotactic body radiation therapy (SBRT) has emerged as a nonoperative treatment option for noninfiltrative primary spine tumors such as meningioma and schwannoma. The majority of initial series used higher doses of 16-24 Gy in 1-3 fractions. The authors hypothesized that lower doses (such as 12-13 Gy in 1 fraction) might provide an efficacy similar to that found with the dose de-escalation commonly used for intracranial radiosurgery to treat acoustic neuroma or meningioma and with a lower risk of toxicity. Read More
J Clin Med 2018 May 23;7(6). Epub 2018 May 23.
Oncologie Medical Department, IPC, 13009 Marseille, France.
We report the case of a 21-year old woman presenting with high blood pressure and raised normetanephrine levels. Indium-111-pentetreotide single photon-emission computed tomography with computed tomography (SPECT/CT) and 2-deoxy-2-[fluorine-18]fluoro-d-glucose (FDG) positron emission tomography/computed tomography (PET/CT) imaging showing isolated tracer-uptake by a 2 cm tumor close to the costovertebral angle of the third thoracic vertebra. Thoracic surgery led to normalization of normetanephrine levels. Read More
Oper Neurosurg (Hagerstown) 2018 May 18. Epub 2018 May 18.
Department of Neurological Surgery, University of California, San Francisco, California.
Background And Importance: Skull base surgery involves the microdissection and intraoperative monitoring of cranial nerves, including cranial nerve XI (CN XI). Manipulation of CN XI can evoke brisk trapezius contraction, which in turn may disturb the surgical procedure and risk patient safety. Here we describe a method for temporarily silencing CN XI via direct intraoperative application of 1% lidocaine. Read More
Oper Neurosurg (Hagerstown) 2018 Dec;15(6):E88-E89
Semmes Murphey Neurologic & Spine Institute, Memphis, Tennessee.
This video demonstrates microsurgical resection of spinal cord hemangioblastoma. Hemangioblastomas are rare, benign, highly vascularized tumors classified as grade I according to World Health Organization classification systems. About 3% of all intramedullary tumors are hemangioblastomas. Read More