Am J Surg Pathol 2021 Apr 23. Epub 2021 Apr 23.
Institute of Pathology, Friedrich Alexander University Erlangen-Nürnberg, University Hospital, Erlangen Department of Thoracic Oncology, Thoraxklinik, National Center for Tumor Diseases at Heidelberg University Hospital Translational Lung Research Center Heidelberg (TLRC), Member of the German Center for Lung Research (DZL) Department of Thoracic Surgery, Thoraxklinik, Heidelberg University Hospital Institute of Pathology, University of Heidelberg, Heidelberg, Germany Department of Pathology, Charles University, Faculty of Medicine in Plzen Bioptical Laboratory Ltd, Plzen, Czech Republic Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY.
Clear cell (hemangioblastoma-like) stromal tumor of the lung (CCST-L) is a recently described distinctive rare pulmonary neoplasm of unknown histogenesis and molecular pathogenesis. Only 7 cases have been reported in 2 recent studies, although additional cases might have been reported under the heading of extraneural pulmonary hemangioblastoma. We herein describe 4 CCST-L cases, 3 of them harboring a YAP1-TFE3 fusion. Read More