6,236 results match your criteria Hellenic journal of cardiology : HJC = Hell?nik? kardiologik? epithe?r?s?[Journal]


DNA methylation profiling implicates exposure to PCBs in the pathogenesis of B-cell chronic lymphocytic leukemia.

Environ Int 2019 Feb 15;126:24-36. Epub 2019 Feb 15.

National Hellenic Research Foundation, Institute of Biology, Medicinal Chemistry and Biotechnology, 48 Vas. Constantinou Ave., Athens 11635, Greece. Electronic address:

Objectives: To characterize the impact of PCB exposure on DNA methylation in peripheral blood leucocytes and to evaluate the corresponding changes in relation to possible health effects, with a focus on B-cell lymphoma.

Methods: We conducted an epigenome-wide association study on 611 adults free of diagnosed disease, living in Italy and Sweden, in whom we also measured plasma concentrations of 6 PCB congeners, DDE and hexachlorobenzene.

Results: We identified 650 CpG sites whose methylation correlates strongly (FDR < 0. Read More

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http://dx.doi.org/10.1016/j.envint.2019.01.068DOI Listing
February 2019

A phonological assessment test for child Greek.

Authors:
Elena Babatsouli

Clin Linguist Phon 2019 Feb 18:1-27. Epub 2019 Feb 18.

a Institute of Monolingual and Bilingual Speech , Chania , Greece.

This article advances a clinical tool for assessing typical and atypical phonological development in children speaking standard Modern Greek or Hellenic (ISO 639.1, el). The proposed tool develops a comprehensive test that is archetypical of the standard idiom and of predominant dialectal variations and seeks to be readily available for logopedics and language researchers of child Greek anywhere. Read More

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http://dx.doi.org/10.1080/02699206.2019.1569164DOI Listing
February 2019

PEO-b-PCL grafted niosomes: The cooperativilty of amphiphilic components and their properties in vitro and in vivo.

Colloids Surf B Biointerfaces 2019 Jan 22;177:338-345. Epub 2019 Jan 22.

Centre of Polymer and Carbon Materials, Polish Academy of Sciences, Zabrze, Poland.

Niosomes belong to drug delivery systems and consist mainly of non-ionic surfactants and cholesterol. In this study, we designed and developed systems composed of non-ionic surfactants i.e. Read More

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http://dx.doi.org/10.1016/j.colsurfb.2019.01.036DOI Listing
January 2019

Stream invertebrate communities are primarily shaped by hydrological factors and ultimately fine-tuned by local habitat conditions.

Sci Total Environ 2019 Feb 10;665:290-299. Epub 2019 Feb 10.

Hellenic Centre for Marine Research, Institute of Marine Biological Resources and Inland Waters, 46.7 km Athens-Sounio Ave., 19013 Anavyssos, Greece.

The environmental factors that determine species richness and community structure in running waters have long been studied, but how these factors hierarchically and/or interactively influence benthic communities remains unclear. To address this research gap, we identified the principal abiotic factors that determine the taxonomic composition and functionality of stream macroinvertebrate communities and explored possible hierarchical and/or interactive patterns. We analyzed a large dataset from Greek rivers, and compared multiple macroinvertebrate metrics and traits between perennial and intermittent watercourses during wet and dry periods. Read More

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http://dx.doi.org/10.1016/j.scitotenv.2019.02.134DOI Listing
February 2019

General and abdominal adiposity and the risk of Parkinson's disease: A prospective cohort study.

Parkinsonism Relat Disord 2019 Feb 8. Epub 2019 Feb 8.

Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Germany. Electronic address:

Introduction: Due to demographic change, an increase in the frequency of Parkinson's disease (PD) patients is expected in the future and, thus, the identification of modifiable risk factors is urgently needed. We aimed to examine the associations of body mass index (BMI) and waist circumference (WC) with incident PD.

Methods: In 13 of the 23 centers of the European Prospective Investigation into Cancer and Nutrition (EPIC) study, a total of 734 incident cases of PD were identified between 1992 and 2012 with a mean follow-up of 12 years. Read More

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http://dx.doi.org/10.1016/j.parkreldis.2019.01.019DOI Listing
February 2019

Authors' reply to: Takotsubo syndrome in Parkinson's disease requires extensive diagnostic workup.

Hellenic J Cardiol 2019 Feb 13. Epub 2019 Feb 13.

First Department of Cardiology, Hippokration General Hospital, National and Kapodistrian University of Athens, Greece.

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http://dx.doi.org/10.1016/j.hjc.2019.02.001DOI Listing
February 2019

Thermal manipulation and GnRHa therapy applied to the reproduction of lambari-do-rabo-amarelo, Astyanax altiparanae females (Characiformes: Characidae) during the non-breeding season.

Gen Comp Endocrinol 2019 Feb 12. Epub 2019 Feb 12.

Instituto de Biociências - USP, São Paulo, SP, Brazil. Electronic address:

Lambari-do-rabo-amarelo Astyanax altiparanae in the wild reproduce during spring and summer, but females undergo vitellogenesis throughout the year, including the non-spawning winter period when water temperatures are low. The present study investigated the physiological role of temperature modulation on the hypothalamus-pituitary-gonads axis of lambari during winter, as well as the effects of gonadotropin releasing hormone agonist (GnRHa) therapy. Captive females were exposed to two different temperatures (20 °C and 27 °C) and were injected weekly with GnRHa for 21 days during winter (Control, CTR; Low dose; LD and high dose of GnRHa, HD). Read More

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http://dx.doi.org/10.1016/j.ygcen.2019.02.016DOI Listing
February 2019

Macrophage Activation-Like Syndrome: A Distinct Entity Leading to Early Death in Sepsis.

Front Immunol 2019 31;10:55. Epub 2019 Jan 31.

Fourth Department of Internal Medicine, Medical School, National and Kapodistrian University of Athens, Athens, Greece.

Hemophagocytic lymphohistocytosis (HLH) is characterized by fulminant cytokine storm leading to multiple organ dysfunction and high mortality. HLH is classified into familial (fHLH) and into secondary (sHLH). fHLH is rare and it is due to mutations of genes encoding for perforin or excretory granules of natural killer (NK) cells of CD8-lymphocytes. Read More

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http://dx.doi.org/10.3389/fimmu.2019.00055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365431PMC
January 2019

Allyl isothiocyanate regulates lysine acetylation and methylation marks in an experimental model of malignant melanoma.

Eur J Nutr 2019 Feb 14. Epub 2019 Feb 14.

Department of Applied Sciences, Translational Biosciences Group, Northumbria University, Ellison Building, Newcastle Upon Tyne, NE1 8ST, UK.

Objective(s): Isothiocyanates (ITCs) are biologically active plant secondary metabolites capable of mediating various biological effects including modulation of the epigenome. Our aim was to characterize the effect of allyl isothiocyanate (AITC) on lysine acetylation and methylation marks as a potential epigenetic-induced anti-melanoma strategy.

Methods: Our malignant melanoma model consisted of (1) human (A375) and murine (B16-F10) malignant melanoma as well as of human; (2) brain (VMM1) and lymph node (Hs 294T) metastatic melanoma; (3) non-melanoma epidermoid carcinoma (A431) and (4) immortalized keratinocyte (HaCaT) cells subjected to AITC. Read More

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http://dx.doi.org/10.1007/s00394-019-01925-6DOI Listing
February 2019
1 Read

Increased Anxiety-Related Behavior, Impaired Cognitive Function and Cellular Alterations in the Brain of Cend1-deficient Mice.

Front Cell Neurosci 2018 29;12:497. Epub 2019 Jan 29.

Laboratory of Cellular and Molecular Neurobiology-Stem Cells, Department of Neurobiology, Hellenic Pasteur Institute, Athens, Greece.

Cend1 is a neuronal-lineage specific modulator involved in coordination of cell cycle exit and differentiation of neuronal precursors. We have previously shown that Cend1 mice show altered cerebellar layering caused by increased proliferation of granule cell precursors, delayed radial granule cell migration and compromised Purkinje cell differentiation, leading to ataxic gait and deficits in motor coordination. To further characterize the effects of Cend1 genetic ablation we determined herein a range of behaviors, including anxiety and exploratory behavior in the elevated plus maze (EPM), associative learning in fear conditioning, and spatial learning and memory in the Morris water maze (MWM). Read More

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http://dx.doi.org/10.3389/fncel.2018.00497DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361865PMC
January 2019
4.289 Impact Factor

Effect of early oseltamivir treatment on mortality in critically ill patients with different types of influenza: a multi-season cohort study.

Clin Infect Dis 2019 Feb 7. Epub 2019 Feb 7.

Hellenic Centre for Disease Control and Prevention, Athens, Greece.

Background: The available evidence on whether neuraminidase inhibitors reduce mortality in patients with influenza is inconclusive, and focuses solely on influenza A/H1N1pdm09. We assessed whether early oseltamivir treatment (≤48 hours from symptom onset) decreases mortality compared to late treatment in a large cohort of critically ill patients with influenza of all types.

Methods: The study included all adults with laboratory-confirmed influenza hospitalized in intensive care units (ICU) in Greece over eight seasons (2010-2011 to 2017-2018) and treated with oseltamivir. Read More

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http://dx.doi.org/10.1093/cid/ciz101DOI Listing
February 2019

Down scaling of climate change scenarii to river basin level: A transdisciplinary methodology applied to Evrotas river basin, Greece.

Sci Total Environ 2019 Apr 26;660:1623-1632. Epub 2018 Dec 26.

Wageningen Environmental Research, 6708 PB Wageningen, Netherlands.

The Mediterranean region is anticipated to be (or, already is) one of the hot spots for climate change, where freshwater ecosystems are under threat from the effects of multiple stressors. Climate change is impacting natural resources and on the functioning of Ecosystem Services. The challenges about modelling climate change impact on water cycle in general and specifically on socio-economic dynamics of the society leads to an exponential amount of results that restrain interpretation and added value of forecasting at local level. Read More

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http://dx.doi.org/10.1016/j.scitotenv.2018.12.369DOI Listing

Prognostic impact of light-chain and transthyretin-related categories in cardiac amyloidosis: a systematic review and meta-analysis.

Hellenic J Cardiol 2019 Feb 8. Epub 2019 Feb 8.

Department of Neurology, The First Affiliated Hospital of China Medical University, Shenyang, China. Electronic address:

Background: Light-chain amyloidosis and transthyretin-related amyloidosis (wild-type and mutated) are three main types of systemic amyloidosis associated with a clinically relevant cardiac involvement. In this study, we compared prognosis in patients with different categories of cardiac amyloidosis using meta-analysis and present a systematic review.

Methods: A systematic literature search was performed through Jan 1, 2018 and two reviewers independently extracted data and assessed risk of bias. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S11099666183054
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http://dx.doi.org/10.1016/j.hjc.2019.01.015DOI Listing
February 2019
4 Reads

Stage 1 hypertension, but not elevated blood pressure, predicts 10-year fatal and non-fatal CVD events in healthy adults: the ATTICA Study.

J Hum Hypertens 2019 Feb 11. Epub 2019 Feb 11.

Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, 70 El. Venizelou Avenue, 176 71, Athens, Greece.

The study evaluated the extent to which high normal blood pressure (HNBP), elevated BP, and Stage 1 hypertension predict 10-year incidence of cardiovascular disease (CVD). A population-based, prospective cohort study was conducted among 3042 randomly selected Greek adults, aged 18-89 years. Following 10-years follow-up (2002-2012), incidence of non-fatal and fatal CVD (ICD-10) was achieved in 2020 participants. Read More

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http://dx.doi.org/10.1038/s41371-019-0169-zDOI Listing
February 2019
1 Read

Personalized physiology-guided resuscitation in highly monitored patients with cardiac arrest-the PERSEUS resuscitation protocol.

Heart Fail Rev 2019 Feb 11. Epub 2019 Feb 11.

School of Medicine, European University Cyprus, Nicosia, Cyprus.

Resuscitation guidelines remain uniform across all cardiac arrest patients, focusing on the delivery of chest compressions to a standardized rate and depth and algorithmic vasopressor dosing. However, individualizing resuscitation to the appropriate hemodynamic and ventilatory goals rather than a standard "one-size-fits-all" treatment seems a promising new therapeutic strategy. In this article, we present a new physiology-guided treatment strategy to titrate the resuscitation efforts to patient's physiologic response after cardiac arrest. Read More

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http://dx.doi.org/10.1007/s10741-019-09772-7DOI Listing
February 2019
1 Read

Changing trends and pretravel preparation of business travelers from Greece during the financial crisis.

Public Health 2019 Feb 7. Epub 2019 Feb 7.

Department for Interventions in Healthcare Facilities, Hellenic Centre for Disease Control and Prevention, Athens, Greece. Electronic address:

Objectives: Unemployment in Greece has been increasing as a result of the financial crisis. The aim of this study was to assess the changing trends of business travelers and their pretravel preparation.

Study Design: Prospective, questionnaire-based study. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00333506183040
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http://dx.doi.org/10.1016/j.puhe.2018.12.015DOI Listing
February 2019
1 Read

Quality control project of NGS HLA genotyping for the 17th International HLA and Immunogenetics Workshop.

Hum Immunol 2019 Feb 6. Epub 2019 Feb 6.

Histocompatibility, Immunogenetics, and Disease Profiling Laboratory, Stanford Blood Center, Palo Alto, CA, USA; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.

The 17th International HLA and Immunogenetics Workshop (IHIW) organizers conducted a Pilot Study (PS) in which 13 laboratories (15 groups) participated to assess the performance of the various sequencing library preparation protocols, NGS platforms and software in use prior to the workshop. The organizers sent 50 cell lines to each of the 15 groups, scored the 15 independently generated sets of NGS HLA genotyping data, and generated "consensus" HLA genotypes for each of the 50 cell lines. Proficiency Testing (PT) was subsequently organized using four sets of 24 cell lines, selected from 48 of 50 PS cell lines, to validate the quality of NGS HLA typing data from the 34 participating IHIW laboratories. Read More

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http://dx.doi.org/10.1016/j.humimm.2019.01.009DOI Listing
February 2019
1 Read

Osteopontin in the host response to Leishmania amazonensis.

BMC Microbiol 2019 Feb 8;19(1):32. Epub 2019 Feb 8.

Immunophysiology and Parasitism Laboratory and Department of Parasites and Insect Vectors, Institut Pasteur, 28 rue du Dr Roux, 75724, Paris Cedex 15, France.

Background: Leishmania (L.) spp are intracellular eukaryotic parasites responsible for cutaneous or visceral leishmaniasis, replicating predominantly in macrophages (MF). In C57BL/6 mice virulence with L. Read More

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http://dx.doi.org/10.1186/s12866-019-1404-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368773PMC
February 2019

Vitamin D Supplementation and Physical Activity of Young Soccer Players during High-Intensity Training.

Nutrients 2019 Feb 6;11(2). Epub 2019 Feb 6.

Department of Health Promotion, Gdansk University of Physical Education and Sport, 80-336 Gdańsk, Poland.

The aim of this study was to confirm that vitamin D supplementation of young soccer players during eight-week high-intensity training would have a significant effect on their motion activity. The subjects were divided into two groups: the experimental one, which was supplemented with vitamin D (SG, = 20), and the placebo group (PG, = 16), which was not supplemented with vitamin D. All the players were subjected to the same soccer training, described as High-Intensity Interval Training (HIIT). Read More

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http://dx.doi.org/10.3390/nu11020349DOI Listing
February 2019
1 Read

Anatomy of Skyrmionic Textures in Magnetic Multilayers.

Adv Mater 2019 Feb 8:e1807683. Epub 2019 Feb 8.

Max Planck Institute for Intelligent Systems, Heisenbergstraße 3, 70569, Stuttgart, Germany.

Room temperature magnetic skyrmions in magnetic multilayers are considered as information carriers for future spintronic applications. Currently, a detailed understanding of the skyrmion stabilization mechanisms is still lacking in these systems. To gain more insight, it is first and foremost essential to determine the full real-space spin configuration. Read More

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http://doi.wiley.com/10.1002/adma.201807683
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http://dx.doi.org/10.1002/adma.201807683DOI Listing
February 2019
5 Reads
17.493 Impact Factor

A framework for reviewing livestock disease reporting systems in high-risk areas: assessing performance and perceptions towards FMD reporting in the Thrace Region of Greece, Bulgaria and Turkey.

Transbound Emerg Dis 2019 Feb 7. Epub 2019 Feb 7.

Food and Agriculture Organization of the United Nations (FAO), Animal Production and Health Division, Viale delle Terme di Caracalla, Roma, 00153, Italy.

Disease reporting is an essential frontline component of surveillance systems, particularly for detecting incursions of new and emerging diseases. It has the advantages of being comprehensive and continuous, with the potential to reduce the time of disease detection and the extent of consequent spread. A number of exotic diseases, including sheep and goat pox, lumpy skin disease, peste des petits ruminants and foot and mouth disease have historically entered into south-eastern Europe through the Thrace Region, which extends across neighbouring areas of Greece, Bulgaria and Turkey. Read More

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http://dx.doi.org/10.1111/tbed.13143DOI Listing
February 2019

Blood-based analysis of type-2 diabetes mellitus susceptibility genes identifies specific transcript variants with deregulated expression and association with disease risk.

Sci Rep 2019 Feb 6;9(1):1512. Epub 2019 Feb 6.

Department of Biochemistry and Molecular Biology, Faculty of Biology, National and Kapodistrian University of Athens, Athens, Greece.

Despite significant progress by genome-wide association studies, the ability of genetic variants to conduce to the prediction or prognosis of type-2 diabetes (T2D) is weak. Expression analysis of the corresponding genes may suggest possible links between single-nucleotide polymorphisms and T2D phenotype and/or risk. Herein, we investigated the expression patterns of 24 T2D-susceptibility genes, and their individual transcript variants (tv), in peripheral blood of T2D patients and controls (CTs), applying RNA-seq and real-time qPCR methodologies, and explore possible associations with disease features. Read More

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http://dx.doi.org/10.1038/s41598-018-37856-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365563PMC
February 2019

Combination of weekly topotecan and gemcitabine as a salvage treatment in patients with recurrent ovarian cancer: a phase I study.

Minerva Ginecol 2019 Feb 6. Epub 2019 Feb 6.

Hellenic Oncology Research Group (HORG), Athens, Greece -

Background: Evaluation of safety of the weekly intravenous gemcitabine/topotecan combination as salvage treatment in patients with recurrent epithelial ovarian cancer.

Methods: Twenty four women with histologically proven relapsed ovarian cancer (ROC) were enrolled in the study. Topotecan (1. Read More

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http://dx.doi.org/10.23736/S0026-4784.19.04249-7DOI Listing
February 2019
1 Read

Tether-directed Regioselective Synthesis of an Equatorialface Bisadduct of Azafullerene Using Cyclo-[2]-octylmalonate.

Chemistry 2019 Feb 5. Epub 2019 Feb 5.

National Hellenic Research Foundation, Theoretical and Physical Chemistry Institute, 48 Vassileos Constantinou Avenue, 11635, Athens, GREECE.

Bisazafullerene (C59N)2 was functionalized under aerobic conditions with cyclo-[2]-octylmalonate via a Mannich-type reaction, furnishing the corresponding monoadduct. A regioselective tether-directed Bingel cyclopropanation reaction was then succeeded on the azafullerene core to yield a single bisadduct. The structure of the formed bisadduct was spectroscopically proved to be C1 symmetrical, which is inherently chiral. Read More

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http://dx.doi.org/10.1002/chem.201900273DOI Listing
February 2019

Structurally Mapping Healthcare Data to HL7 FHIR through Ontology Alignment.

J Med Syst 2019 Feb 5;43(3):62. Epub 2019 Feb 5.

Department of Digital Systems, University of Piraeus, 80, Karaoli and Dimitriou Str, Piraeus, 18534, Piraeus, Greece.

Current healthcare services promise improved life-quality and care. Nevertheless, most of these entities operate independently due to the ingested data' diversity, volume, and distribution, maximizing the challenge of data processing and exchange. Multi-site clinical healthcare organizations today, request for healthcare data to be transformed into a common format and through standardized terminologies to enable data exchange. Read More

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http://link.springer.com/10.1007/s10916-019-1183-y
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http://dx.doi.org/10.1007/s10916-019-1183-yDOI Listing
February 2019
3 Reads

Determinants of Erythrocyte Lead Levels in 454 Adults in Florence, Italy.

Int J Environ Res Public Health 2019 Feb 1;16(3). Epub 2019 Feb 1.

Cancer Risk Factors and Lifestyle Epidemiology Unit, Institute for Cancer Research, Prevention and Clinical Network (ISPRO), 50139 Florence, Italy.

: Lead exposure, even at low levels, is associated with adverse health effects in humans. We investigated the determinants of individual lead levels in a general population-based sample of adults from Florence, Italy. : Erythrocyte lead levels were measured (using inductively coupled plasma-mass spectrometry) in 454 subjects enrolled in the Florence cohort of the European Prospective Investigation into Cancer and Nutrition (EPIC) study in 1992⁻1998. Read More

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http://www.mdpi.com/1660-4601/16/3/425
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http://dx.doi.org/10.3390/ijerph16030425DOI Listing
February 2019
4 Reads

Th17 serum cytokines in relation to laboratory-confirmed respiratory viral infection: A pilot study.

J Med Virol 2019 Feb 4. Epub 2019 Feb 4.

4th Department of Internal Medicine, University of Athens Medical School, Athens, Greece.

Background: Th17 cytokines are associated with modulation of inflammation and may be beneficial in clearing influenza infection in experimental models. The Th17 cytokine profile was evaluated in a pilot study of respiratory virus infections.

Methods: Consecutive patients with symptoms of respiratory tract infection visiting the emergency department of a tertiary care hospital during the winter influenza season of 2014 to 2015 were evaluated. Read More

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http://dx.doi.org/10.1002/jmv.25406DOI Listing
February 2019
3 Reads
2.347 Impact Factor

National Survey of Morbidity and Risk Factors (EMENO): Protocol for a Health Examination Survey Representative of the Adult Greek Population.

JMIR Res Protoc 2019 Feb 4;8(2):e10997. Epub 2019 Feb 4.

Department of Hygiene, Epidemiology and Medical Statistics, Medical School, National and Kapodistrian University of Athens, Athens, Greece.

Background: Main causes of death in Greece are cardiovascular diseases (CVDs), malignant neoplasms, respiratory diseases, and road traffic crashes. To assess the population health status, monitor health systems, and adjust policies, national population-based health surveys are recommended. The previous health surveys that were conducted in Greece were restricted to specific regions or high-risk groups. Read More

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http://dx.doi.org/10.2196/10997DOI Listing
February 2019
2 Reads

Genomics, environment and balancing selection in behaviorally bimodal populations: the caribou case.

Mol Ecol 2019 Feb 3. Epub 2019 Feb 3.

Dept. of Biological Sciences, Faculty of Science and Veterinary Medicine (Joint Appointment), University of Calgary, Calgary, AB, T2N 1N4, Canada.

Selection forces that favor different phenotypes in different environments can change frequencies of genes between populations along environmental clines. Clines are also compatible with balancing forces, such as negative frequency-dependent selection (NFDS), which maintains phenotypic polymorphisms within populations. For example, NFDS is hypothesized to maintain partial migration, a dimorphic behavioral trait prominent in species where only a fraction of the population seasonally migrates. Read More

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http://dx.doi.org/10.1111/mec.15039DOI Listing
February 2019

The Gene Toolkit Implicated in Functional Sex in Sparidae Hermaphrodites: Inferences From Comparative Transcriptomics.

Front Genet 2018 18;9:749. Epub 2019 Jan 18.

Hellenic Centre for Marine Research, Institute of Marine Biology, Biotechnology and Aquaculture, Heraklion, Greece.

Sex-biased gene expression is the mode through which sex dimorphism arises from a nearly identical genome, especially in organisms without genetic sex determination. Teleost fishes show great variations in the way the sex phenotype forms. Among them, Sparidae, that might be considered as a model family displays a remarkable diversity of reproductive modes. Read More

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http://dx.doi.org/10.3389/fgene.2018.00749DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345689PMC
January 2019

Acute rheumatic fever: A neglected diagnosis in Greece.

Hellenic J Cardiol 2019 Jan 31. Epub 2019 Jan 31.

Department of Paediatrics, "Karamandaneion"General Paediatric Hospital Patras.

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http://dx.doi.org/10.1016/j.hjc.2019.01.013DOI Listing
January 2019
1 Read

Uncommon Cause of Paradoxical Low - Flow Low - Gradient Severe Aortic Stenosis.

Hellenic J Cardiol 2019 Jan 31. Epub 2019 Jan 31.

St Luke's Hospital, Thessaloniki, Greece. Electronic address:

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http://dx.doi.org/10.1016/j.hjc.2019.01.014DOI Listing
January 2019
1 Read

Transcatheter Aortic Valve Implantation using 3-D printing modeling assistance. A single center experience.

Hellenic J Cardiol 2019 Jan 31. Epub 2019 Jan 31.

Vascular Unit, 1st University Surgical Department, Aristotle University, Papageorgiou General Hospital, Thessaloniki, Greece.

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http://dx.doi.org/10.1016/j.hjc.2019.01.012DOI Listing
January 2019

Impact of the General Data Protection Regulation on Clinical Proteomics Research.

Authors:
Elena Critselis

Proteomics Clin Appl 2019 Feb 1:e1800199. Epub 2019 Feb 1.

Proteomics Facility, Center for Systems Biology, Biomedical Research Foundation of the Academy of Athens, Athens, 11527, Greece.

The recently implemented General Data Protection Regulation (GDPR) has promising attributes for ensuring the protection of personal data collected and processed for clinical proteomic investigations. However, there exist ever increasing alarming concerns regarding its implications upon the future of clinical proteomics research both within and beyond the European Union. The main issues of concern regard GDPR legislative requirements for informed consent for study subjects' data collection and processing, data anonymization, and data storage and/or sharing, particularly in research areas which readily utilize databanks and biobanks, such as clinical proteomics investigations. Read More

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http://dx.doi.org/10.1002/prca.201800199DOI Listing
February 2019

The dynamics of the pharmaceutical and personal care product interactive capacity under the effect of artificial enrichment of soil with heavy metals and of wastewater reuse.

Sci Total Environ 2019 Jan 12;662:537-546. Epub 2019 Jan 12.

Hellenic Open University, School of Science and Technology, Aristotelous 18, 26335 Patras, Greece. Electronic address:

A greenhouse experiment was conducted, using a randomized block design, including twelve heavy metal (Mn, Zn, Cu, Cd, Co, Cr, Ni, Pb) mixture treatments, with each metal participating in the treatment with 0, 2, 4, 6, 8, 10, and 12 mg/kg, respectively. Common beet (Beta vulgaris L.) was chosen as test plant. Read More

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http://dx.doi.org/10.1016/j.scitotenv.2019.01.111DOI Listing
January 2019

The Emerging Role of Bone Markers in Diagnosis and Risk Stratification of Patients With Coronary Artery Disease.

Angiology 2019 Jan 29:3319718822625. Epub 2019 Jan 29.

6 First Department of Cardiology, Hippokration Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece.

Molecules that govern bone metabolism, such as osteoprotegerin (OPG) and osteopontin (OPN), have been isolated from other tissues, including blood vessels. Atherosclerosis and coronary artery disease (CAD) are leading causes of mortality worldwide. Despite novel biochemical and imaging techniques, early detection of CAD is still unsatisfactory. Read More

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http://dx.doi.org/10.1177/0003319718822625DOI Listing
January 2019

One-carbon metabolism biomarkers and risk of urothelial cell carcinoma in the European prospective investigation into cancer and nutrition.

Int J Cancer 2019 Jan 29. Epub 2019 Jan 29.

Radboud University Medical Center, Radboud Institute for Health Sciences, Nijmegen, The Netherlands.

Published associations between dietary folate and bladder cancer risk are inconsistent. Biomarkers may provide more accurate measures of nutrient status. This nested case-control analysis within the European Prospective Investigation into Cancer and Nutrition (EPIC) investigated associations between pre-diagnostic serum folate, homocysteine, vitamins B6 and B12 and the risk of urothelial cell carcinomas of the bladder (UCC). Read More

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http://doi.wiley.com/10.1002/ijc.32165
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http://dx.doi.org/10.1002/ijc.32165DOI Listing
January 2019
3 Reads

Template synthesis of defect-rich MoS-based assemblies as electrocatalytic platforms for hydrogen evolution reaction.

Chem Commun (Camb) 2019 Feb;55(14):2078-2081

Theoretical and Physical Chemistry Institute, National Hellenic Research Foundation, 48 Vassileos Constantinou Avenue, 11635 Athens, Greece.

Defect-rich MoS2 nanostructures were synthesized in solution by a microwave-assisted process, employing either a sacrificial soft template (CaCO3) or a non-sacrificial hard template (graphene oxide) and the electrocatalytic performance towards the hydrogen evolution reaction was found to be superior for the latter. Read More

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http://xlink.rsc.org/?DOI=C9CC00051H
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http://dx.doi.org/10.1039/c9cc00051hDOI Listing
February 2019
2 Reads

Using surgical risk scores in non-surgically treated infective endocarditis patients.

Hellenic J Cardiol 2019 Jan 25. Epub 2019 Jan 25.

Department of Thoracic and Cardiovascular Surgery, Jean Minjoz University Hospital, Besançon, France.

Background: The accuracy of surgical scores in predicting in-hospital mortality for non-surgically treated patients with infective endocarditis (IE) has not been yet explored.

Methods: Patients having definite IE who did not undergo valve surgery were selected from the database of seven French administrative areas (Association pour l'Étude et la Prévention de l'Endocardite Infectieuse [AEPEI] registry, 2008). The patients were scored using: (a) six systems specifically devised to predict in-hospital mortality after surgery for IE, (b) three commonly used risk scores for heart surgery, and (c) a risk score for predicting six-month mortality in IE either after surgery or medical therapy. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S11099666183052
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http://dx.doi.org/10.1016/j.hjc.2019.01.008DOI Listing
January 2019
3 Reads

Irisin: good or bad for the bone? A new path forward after the reported discovery of irisin receptor?

Metabolism 2019 Jan 25. Epub 2019 Jan 25.

Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S00260495193002
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http://dx.doi.org/10.1016/j.metabol.2019.01.013DOI Listing
January 2019
1 Read

A harmonized and coordinated assessment of the abundance and composition of seafloor litter in the Adriatic-Ionian macroregion (Mediterranean Sea).

Mar Pollut Bull 2019 Feb 15;139:412-426. Epub 2019 Jan 15.

Hellenic Center for Marine Research, Institute of Oceanography, 46.7 Km Athens Sounio, Mavro Lithari, P.O. Box 19013, Anavissos, Attica, Greece. Electronic address:

Marine litter is a threat to marine life and an economic burden for coastal communities, but efforts to address the issue are hampered by the lack of data for many countries. We performed the first harmonized assessment of seafloor litter (trawl and visual surveys) in six countries of the Adriatic-Ionian macroregion. Seafloor litter showed an uneven distribution throughout the area, with large differences in litter densities and composition among countries and locations. Read More

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http://dx.doi.org/10.1016/j.marpolbul.2019.01.017DOI Listing
February 2019
2.991 Impact Factor

MIDCAB versus Off-pump CABG: Comparative Study.

Hellenic J Cardiol 2019 Jan 24. Epub 2019 Jan 24.

Department of Cardiovascular Surgery, The Second Hosptial of Shandong University, Jinan 250033, PR China.

Objective: To investigate the clinical significance of minimally invasive direct coronary artery bypass (MIDCAB).

Methods: 300 patients admitted to the Second Hosptial of Shandong University Hospital from March 2006 to February 2010 were retrospectively analyzed and received off-pump operation under general anesthesia. According to surgical methods, patients were divided into the MIDCAB group (n=90) and the median sternotomy off-pump coronary artery bypass (OPCAB) group, namely the OPCAB group (n=210). Read More

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http://dx.doi.org/10.1016/j.hjc.2018.12.004DOI Listing
January 2019
2 Reads

The safety of renal denervation as assessed by optical coherence tomography: pre- and post-procedure comparison with multi-electrode ablation catheter in animal experiment.

Hellenic J Cardiol 2019 Jan 23. Epub 2019 Jan 23.

Department of Cardiology, Huadong Hospital affiliated to Fudan University, Shanghai, China. Electronic address:

Objective: Prove the effectiveness and safety of multi-electrode ablation catheter in renal denervation (RDN) by optical coherence tomography (OCT).

Methods: 16 renal arteries were enrolled from 8 pigs. Angiography and OCT were used to obtain the morphology changes before RDN and 1-month follow-up. Read More

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http://dx.doi.org/10.1016/j.hjc.2019.01.009DOI Listing
January 2019
2 Reads

Antibody persistence 5 years after a 13-valent pneumococcal conjugate vaccine in asplenic patients with β-thalassemia: assessing the need for booster.

Ann Hematol 2019 Mar 25;98(3):775-779. Epub 2019 Jan 25.

Infectious Diseases Unit, 1st Department of Paediatrics, Aghia Sofia Children's Hospital, National and Kapodistrian University of Athens, Thivon & Levadias Str, 115 27, Athens, Greece.

Streptococcus pnemoniae is a major cause of morbidity and mortality among splenectomised patients with β-thalassemia major. We have previously shown that a 13-valent pneumococcal conjugate vaccine (PCV13) induces robust early immune responses in such patients, while history of repeated immunisations with the 23-valent polysaccharide pneumococcal vaccine (PPSV23) results in attenuation of the response to PCV13. However, the duration of vaccine-induced protection in splenectomised thalassemic patients and the associated need for booster immunisation remains unclear. Read More

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http://link.springer.com/10.1007/s00277-019-03615-z
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http://dx.doi.org/10.1007/s00277-019-03615-zDOI Listing
March 2019
2 Reads

Supraventricular tachycardia with QRS and cycle length alternans. What is the diagnosis?

Hellenic J Cardiol 2019 Jan 22. Epub 2019 Jan 22.

2(nd) Department of Cardiology, General Hospital of Nikea-Piraeus "Agios Panteleimon", D. Mantouvalou 3, 18454, Piraeus, Greece.

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http://dx.doi.org/10.1016/j.hjc.2019.01.006DOI Listing
January 2019

Takotsubo syndrome in Parkinson's disease requires extensive diagnostic work-up.

Hellenic J Cardiol 2019 Jan 22. Epub 2019 Jan 22.

Division Cerebrovascular Disease Unit, IRCCS Foundation "C. Besta", Neurological Institute, Milan, Italy.

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http://dx.doi.org/10.1016/j.hjc.2019.01.007DOI Listing
January 2019

Malignant Interventricular Liposarcoma.

Hellenic J Cardiol 2019 Jan 22. Epub 2019 Jan 22.

Thessaloniki Heart Institute, St Luke's Hospital, Thessaloniki, Greece.

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http://dx.doi.org/10.1016/j.hjc.2019.01.011DOI Listing
January 2019

Dual antiplatelet therapy in acute coronary syndrome after stent implantation: How short is short and how long is long?

Authors:
Costas Tsioufis

Hellenic J Cardiol 2019 Jan 23. Epub 2019 Jan 23.

National and Kapodistrian University of Athens, First Cardiology Clinic, Medical School, Hippokration Hospital, 114 Vas. Sofias Ave 11527, Athens, Greece. Electronic address:

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http://dx.doi.org/10.1016/j.hjc.2018.11.010DOI Listing
January 2019

Identification of Sex-Specific Transcriptome Responses to Polychlorinated Biphenyls (PCBs).

Sci Rep 2019 Jan 24;9(1):746. Epub 2019 Jan 24.

Department of Toxicogenomics, Maastricht University, Maastricht, The Netherlands.

PCBs are classified as xenoestrogens and carcinogens and their health risks may be sex-specific. To identify potential sex-specific responses to PCB-exposure we established gene expression profiles in a population study subdivided into females and males. Gene expression profiles were determined in a study population consisting of 512 subjects from the EnviroGenomarkers project, 217 subjects who developed lymphoma and 295 controls were selected in later life. Read More

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http://dx.doi.org/10.1038/s41598-018-37449-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346099PMC
January 2019