35,697 results match your criteria Helicobacter Pylori Infection


Nodularity-like appearance in the cardia: novel endoscopic findings for infection.

Endosc Int Open 2020 Jun 25;8(6):E770-E774. Epub 2020 May 25.

Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.

  -associated nodular gastritis, which is associated with follicular lymphoid hyperplasia, is mainly recognized in the antrum. However, we have also observed nodularity-like appearance in the cardia. This study aimed to investigate the clinical significance of cardiac nodularity-like appearance in -associated gastritis. Read More

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http://dx.doi.org/10.1055/a-1136-9890DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247899PMC

TLR2, TLR4 and TLR10 Shape the Cytokine and Chemokine Release of -Infected Human DCs.

Int J Mol Sci 2020 May 29;21(11). Epub 2020 May 29.

Department of Biosciences, University of Salzburg, 5020 Salzburg, Austria.

is a stomach pathogen that persistently colonizes the gastric mucosa, often leading to chronic inflammation and gastric pathologies. Although infection with is the primary risk factor for gastric cancer, the underlying mechanisms of pathogen persistence and consequential chronic inflammation are still not well understood. Conventional dendritic cells (cDCs), which are among the first immune cells to encounter in the gastric lining, and the cytokines and chemokines they secrete, contribute to both acute and chronic inflammation Therefore, this study aimed to unravel the contributions of specific signaling pathways within human CD1c cDCs (cDC2s) to the composition of secreted cytokines and chemokines in infection. Read More

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http://dx.doi.org/10.3390/ijms21113897DOI Listing

Analysis of Somatostatin-Secreting Gastric Delta Cells according to Upper Abdominal Symptoms and Infection in Children.

Pediatr Gastroenterol Hepatol Nutr 2020 May 8;23(3):243-250. Epub 2020 May 8.

Department of Pediatrics, Hanyang University College of Medicine, Seoul, Korea.

Purpose: Gastric delta cells (D-cells), which are somatostatin-secreting cells, are the main paracrine inhibitor of acid secretion. The number of D-cells was studied in children presenting with upper gastrointestinal (UGI) disease.

Methods: We retrospectively investigated the number of D-cells in the gastric body and antrum through immunofluorescence examinations according to symptoms, endoscopic findings, and infection in 75 children who visited Hanyang University Hospital Pediatrics. Read More

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http://dx.doi.org/10.5223/pghn.2020.23.3.243DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231749PMC

Incidence of metachronous gastric cancer after endoscopic submucosal dissection associated with eradication status of Helicobacter pylori.

Eur J Gastroenterol Hepatol 2020 May 29. Epub 2020 May 29.

Department of Gastroenterology, Yokohama City University Graduate School of Medicine, Yokohama, Japan.

Objective: This study compared the clinicopathological features and treatment outcomes of patients with primary early gastric cancers (EGCs) who had undergone Helicobacter pylori eradication and endoscopic submucosal dissection (ESD) with those of patients who were H. pylori-positive and had undergone ESD. Additionally, we investigated the incidence of metachronous cancer in these patients. Read More

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http://dx.doi.org/10.1097/MEG.0000000000001788DOI Listing

Association Between Infection and Otitis Media With Effusion Risk in Children: A Systematic Review and Meta-analysis.

Otolaryngol Head Neck Surg 2020 Jun 2:194599820921861. Epub 2020 Jun 2.

Department of Otolaryngology-Head and Neck Surgery, Hearing Center/Hearing and Speech Science Laboratory, West China Hospital of Sichuan University, Chengdu, China.

Objective: To investigate the potential correlation between infection and otitis media with effusion (OME) risk in children.

Data Sources: Electronic databases were searched, including Cochrane Library, PubMed, Embase, China Biology Medicine disc, China Science and Technology Journal Database, Wanfang Database, and China National Knowledge Infrastructure Database.

Review Methods: A systematic review and meta-analysis were conducted with Revman 5. Read More

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http://dx.doi.org/10.1177/0194599820921861DOI Listing

Nobiletin Inhibits Helicobacterium pylori Infection-Induced Gastric Carcinogenic Signaling by Blocking Inflammation, Apoptosis, and Mitogen-Activated Protein Kinase Events in Gastric Epithelial-1 Cells.

J Environ Pathol Toxicol Oncol 2020 ;39(1):77-88

Department of General Surgery, The First People's Hospital of Yunnan Province, The Affiliated Hospital of Kunming University of Science and Technology, Kunming, Yunnan, 650032, China.

Helicobacter pylori causes a Gram-negative bacterial infection that can increase the risk of gastric cancer. Consequently, meticulous prevention of an H. pylori infection is significant for averting gastric cancer in humans. Read More

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http://dx.doi.org/10.1615/JEnvironPatholToxicolOncol.2020031272DOI Listing

Expression and Significance of MyD88 in Patients With Gastric Cardia Cancer in a High-Incidence Area of China.

Front Oncol 2020 14;10:559. Epub 2020 May 14.

Department of Pathology, Shantou University Medical College, Shantou, China.

Gastric cardia cancer (GCC) arises in the area of the stomach adjoining the esophageal-gastric junction and has unique risk factors. It was suggested that the involvement of is associated with GCC from high-risk population. Myeloid differentiation factor 88 (MyD88) is a crucial adaptor molecule in Toll-like signaling pathway recognizing . Read More

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http://dx.doi.org/10.3389/fonc.2020.00559DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239990PMC

Anti-microbial and anti-inflammatory effects of Cheonwangbosim-dan against -induced gastritis.

J Vet Sci 2020 May;21(3):e39

Department of Veterinary Pathology, College of Veterinary Medicine, Chungnam National University, Daejeon 34134, Korea.

Background: There are various species colonizing the stomachs of animals. Although usually cause asymptomatic infection in the hosts, clinical signs can occur due to gastritis associated with in animals. Among them, is strongly associated with chronic gastritis, gastric ulcers, and gastric cancers. Read More

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http://dx.doi.org/10.4142/jvs.2020.21.e39DOI Listing

Awareness and attitudes regarding Helicobacter pylori infection in Chinese physicians and public population: A national cross-sectional survey.

Helicobacter 2020 May 31:e12705. Epub 2020 May 31.

Department of Gastroenterology, Changhai Hospital, Naval Medical University, Shanghai, China.

Background: There is a lack of reports on the awareness of Helicobacter pylori (H pylori) prevention and treatment in the general Chinese population. And whether the knowledge level will affect their action toward screening was unknown. This study aimed to conduct a national survey on the knowledge, attitudes, and practice regarding H pylori infection in Chinese physicians and the public. Read More

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http://dx.doi.org/10.1111/hel.12705DOI Listing

Impact of gastric Helicobacter pylori infection on nasal mucociliary clearance.

Eur Arch Otorhinolaryngol 2020 May 31. Epub 2020 May 31.

Department of Otolaryngology, Faculty of Medicine, Bozok University, Atatürk Yolu 7. Km, 66100, Yozgat, Turkey.

Objectives: This study aimed to investigate the relationship between the presence of gastric Helicobacter pylori (HP) infection and nasal mucociliary clearance (NMC) time and to analyze the effect of HP eradication on NMC time.

Materials And Methods: Patients who underwent gastric biopsy and had a positive result for HP constituted the study group, while the control group consisted of the patients who had a negative biopsy result. Two groups were compared in terms of NMC times. Read More

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http://dx.doi.org/10.1007/s00405-020-06089-2DOI Listing

Periodontal disease and Helicobacter pylori infection in oral cavity: a meta-analysis of 2727 participants mainly based on Asian studies.

Clin Oral Investig 2020 May 30. Epub 2020 May 30.

Department of Periodontics and Oral Biology, School and Hospital of Stomatology, China Medical University, Liaoning Provincial Key Laboratory of Oral Diseases, Heping Distrct, Nanjing North Street No.117, Shenyang, 110002, China.

Objectives: To assess the association between periodontal disease and Helicobacter pylori (H. pylori) infection in oral cavity.

Materials And Methods: We searched PubMed, Embase, Web of Science, Cochrane library, Gray literature, and clinicaltrials. Read More

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http://dx.doi.org/10.1007/s00784-020-03330-4DOI Listing

Population-based Study of Helicobacter pylori infection and Antibiotic Resistance in Bhutan.

Int J Infect Dis 2020 May 28. Epub 2020 May 28.

Department of Environmental and Preventive Medicine, Oita University Faculty of Medicine, Yufu, Japan.

Objectives: Bhutan suffers from a high prevalence of Helicobacter pylori (H. pylori) infection and gastric cancer-related mortality. In preparation for a country-wide H. Read More

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http://dx.doi.org/10.1016/j.ijid.2020.05.077DOI Listing

Saccharomyces boulardii CNCM I-745: A Non-bacterial Microorganism Used as Probiotic Agent in Supporting Treatment of Selected Diseases.

Curr Microbiol 2020 May 29. Epub 2020 May 29.

Department of Surgical Oncology, Medical University of Gdansk, Mariana Smoluchowskiego 17, 80-214, Gdańsk, Poland.

The yeast Saccharomyces boulardii CNCM I-745 is a unique, non-bacterial microorganism classified as a probiotic agent. In this review article, at first, we briefly summarized the mechanisms responsible for its probiotic properties, e.g. Read More

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http://dx.doi.org/10.1007/s00284-020-02053-9DOI Listing

Relationship between the severity of Helicobacter pylori infection and neutrophil and lymphocyte ratio and mean platelet volume in children.

Arch Argent Pediatr 2020 Jun;118(3):e241-e245

Department of Pathology, Mersin City Training and Research Hospital, Mersin, Turkey.

Introduction: HP causes local inflammation in the stomach and a systemic humoral immune response. No relationship was found in adult studies investigating the association between HP infection and neutrophil/lymphocyte ratio (NLR) and mean platelet volume (MPV). To our knowledge, there is no study in children. Read More

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http://dx.doi.org/10.5546/aap.2020.eng.e241DOI Listing

Risk for Irritable Bowel Syndrome in Patients with Helicobacter Pylori Infection: A Nationwide Population-Based Study Cohort Study in Taiwan.

Int J Environ Res Public Health 2020 May 25;17(10). Epub 2020 May 25.

Graduate Institute of Medical Sciences, National Defense Medical Center, Taipei 11490, Taiwan, China.

Background: The association between () infection and the risk of developing irritable bowel syndrome (IBS) has yet to be investigated; thus, we conducted this nationwide cohort study to examine the association in patients from Taiwan.

Methods: A total of approximately 2669 individuals with newly diagnosed H. pylori infection and 10,676 age- and sex-matched patients without a diagnosis of H. Read More

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http://dx.doi.org/10.3390/ijerph17103737DOI Listing

Protective effects of membrane vesicles against stress and antimicrobial agents.

Microbiology 2020 May 28. Epub 2020 May 28.

School of Science and Technology, Nottingham Trent University, Nottingham, NG11 8NS, UK.

Outer-membrane vesicles (OMVs) produced by deliver bacterial components to host cells, provide a mechanism for stabilization of secreted components and may allow the bacteria to exert 'long-range' effects in the gastric niche, promoting persistence. In addition to their well-characterized host cell interactions, membrane vesicles improve stress survival in other bacterial species, and are constitutively produced by both pathogenic and non-pathogenic bacteria. We aimed to determine whether OMVs could improve survival of a range of stressors. Read More

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http://dx.doi.org/10.1099/mic.0.000934DOI Listing

Sex differences in the relationship among alcohol, smoking, and infection in asymptomatic individuals.

J Int Med Res 2020 May;48(5):300060520926036

Department of Gastroenterology and Hepatology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.

Objective: We aimed to investigate the relationship of infection with alcohol and smoking.

Methods: We conducted a cross-sectional study among participants who underwent health check-ups for infection between January 2013 and March 2017. We subsequently investigated the relationship of infection with alcohol and smoking. Read More

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http://dx.doi.org/10.1177/0300060520926036DOI Listing

Association of infection with colorectal polyps and malignancy in China.

World J Gastrointest Oncol 2020 May;12(5):582-591

Department of Gastroenterology, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi 830001, Xinjiang Uygur Autonomous Region, China.

Background: Gastric () infection is related to chronic gastritis, gastroduodenal ulcer, and gastric malignancies; whether this infection is related to colorectal polyps and colorectal cancer (CRC), remains debatable.

Aim: To investigate the relationship between gastric infection and the risk of colorectal polyps and CRC.

Methods: We retrospectively analyzed 3872 patients with colorectal polyps who underwent colonoscopy and pathological diagnosis. Read More

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http://dx.doi.org/10.4251/wjgo.v12.i5.582DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235179PMC

Characterization and strong risk association of to polymorphism and and their influence on mRNA expression in gastric cancer.

World J Gastrointest Oncol 2020 May;12(5):535-548

Department of Molecular Biology, São José do Rio Preto School of Medicine, São José do Rio Preto, São Paulo 15090-000, Brazil.

Background: Toll-like receptor-2 () is responsible for recognizing () and activating the immune response. Polymorphisms in may modulate gastric carcinogenesis.

Aim: To evaluate whether the (rs3804099) and - (rs111200466) polymorphisms contribute to gastric carcinogenesis in the Brazilian population, and to determine the influence of both polymorphisms and infection on mRNA expression. Read More

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http://dx.doi.org/10.4251/wjgo.v12.i5.535DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235183PMC

Clinical implications of gastric complications on levodopa treatment in Parkinson's disease.

Parkinsonism Relat Disord 2020 May 11. Epub 2020 May 11.

Department of Neurology, University of Kansas Medical Center, Kansas City, KS, USA.

Disorders of the gastrointestinal (GI) tract are common and distressing nonmotor symptoms of Parkinson's disease (PD) that can adversely affect levodopa absorption and lead to OFF periods, also known as motor fluctuations. Gastroparesis, which is primarily defined as delayed gastric emptying (DGE), and Helicobacter pylori infection, which is present with increased frequency in PD, are among the most common and important GI disorders reported in PD that may impair oral levodopa absorption and increase OFF time. Symptoms of gastroparesis include nausea, vomiting, postprandial bloating, fullness, early satiety, abdominal pain, and weight loss. Read More

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http://dx.doi.org/10.1016/j.parkreldis.2020.05.001DOI Listing

Family History of Gastric Cancer and Helicobacter pylori Treatment. Reply.

N Engl J Med 2020 05;382(22):2171-2172

National Cancer Center, Goyang, South Korea

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http://dx.doi.org/10.1056/NEJMc2003542DOI Listing

Family History of Gastric Cancer and Helicobacter pylori Treatment.

N Engl J Med 2020 05;382(22):2171

First Affiliated Hospital of Guangxi Medical University, Nanning, China

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http://dx.doi.org/10.1056/NEJMc2003542DOI Listing

Family History of Gastric Cancer and Helicobacter pylori Treatment.

N Engl J Med 2020 05;382(22):2170-2171

VA Palo Alto Health Care System, Palo Alto, CA

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http://dx.doi.org/10.1056/NEJMc2003542DOI Listing

Family History of Gastric Cancer and Helicobacter pylori Treatment.

N Engl J Med 2020 05;382(22):2170

Marshall B. Ketchum University, Fullerton, CA

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http://dx.doi.org/10.1056/NEJMc2003542DOI Listing

Prevalence and Antibiotic Resistance Patterns of Helicobacter pylori Infection in Koh Kong, Cambodia.

Asian Pac J Cancer Prev 2020 May 1;21(5):1409-1413. Epub 2020 May 1.

Department of Environmental and Preventive Medicine, Oita University Faculty of Medicine, Yufu, Japan.

Background: Gastric cancer, which is the leading cause of cancer mortality in Cambodia, can be prevented by Helicobacter pylori (H. pylori) eradication. There is limited data about H. Read More

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http://dx.doi.org/10.31557/APJCP.2020.21.5.1409DOI Listing

Sex differences between Helicobacter pylori infection and cholesterol levels in an adult health checkup program.

Helicobacter 2020 May 26:e12704. Epub 2020 May 26.

Department of Internal Medicine, Kosin University College of Medicine, Busan, Korea.

Background: Helicobacter pylori (H pylori) infection is suggested to be a risk factor of metabolic syndrome (MS) and lipid abnormalities. The aim of this study was to investigate the influence of H pylori infection on MS and lipid abnormalities according to sex differences.

Materials And Methods: We analyzed a total of 4551 adults who received health checkups from January 2016 to May 2017. Read More

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http://dx.doi.org/10.1111/hel.12704DOI Listing

Integrative Analysis of Differential lncRNA/mRNA Expression Profiling in Infection-Associated Gastric Carcinogenesis.

Front Microbiol 2020 8;11:880. Epub 2020 May 8.

Department of Gastroenterology, The First Affiliated Hospital of Nanchang University, Nanchang, China.

() infection is the greatest known risk factor for gastric cancer (GC). Long non-coding RNAs (lncRNAs) are implicated in multiple biological processes. However, their contribution in -associated GC remains largely unknown. Read More

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http://dx.doi.org/10.3389/fmicb.2020.00880DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225608PMC

Helicobacter pylori was not detected in oral squamous cell carcinomas from cohorts of Norwegian and Nepalese patients.

Sci Rep 2020 May 26;10(1):8737. Epub 2020 May 26.

Department of Oral Biology, Faculty of Dentistry, University of Oslo, Oslo, Norway.

Helicobacter pylori (HP) infection is an established causative agent for gastric cancer. Although the oral cavity is a part of the gastrointestinal system, the presence and possible causative role of HP in oral squamous cell carcinoma (OSCC) is a subject of controversy. Therefore, the current study aimed to investigate HP infection in two cohorts of OSCC patients with different demographic characteristics, lifestyles and habitual risk factors. Read More

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http://dx.doi.org/10.1038/s41598-020-65694-7DOI Listing

Infection: Clinical, Endoscopic, and Histological Findings in Lebanese Pediatric Patients.

Int J Pediatr 2020 11;2020:4648167. Epub 2020 May 11.

Department of Pediatrics, Makassed General Hospital, Beirut, Lebanon.

Background: () is a common and universally distributed bacterial infection. However, in children, active gastritis and ulcer are rarely seen.

Objectives: The aims of this study were to establish the prevalence of infection and to compare the clinical, endoscopic, and histopathological findings between infected and noninfected pediatric patients at Makassed General Hospital. Read More

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http://dx.doi.org/10.1155/2020/4648167DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238322PMC

The role of gastric microbiota in gastric cancer.

Gut Microbes 2020 May 23:1-11. Epub 2020 May 23.

Department of Population Health, New York University School of Medicine , New York, New York, USA.

Gastric cancer represents one of the leading causes of cancer deaths worldwide. () infection is the strongest risk factor associated with gastric cancer. Due to new molecular techniques allowing greater identification of stomach microbes, investigators are beginning to examine the role that bacteria other than play in gastric cancer development. Read More

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http://dx.doi.org/10.1080/19490976.2020.1762520DOI Listing

Assessment of real-time PCR for Helicobacter pylori DNA detection in stool with co-infection of intestinal parasites: a comparative study of DNA extraction methods.

BMC Microbiol 2020 May 24;20(1):131. Epub 2020 May 24.

Department of Infectious-Tropical Diseases and Microbiology, IRCCS Sacro Cuore Don Calabria Hospital, Via Don A. Sempreboni, 5 - 37024 Negrar di Valpolicella, Verona, Italy.

Background: Many studies reported high prevalence of H. pylori infection among patients co-infected with intestinal parasites. Molecular approach for the DNA detection of those microbes in stool have been proposed. Read More

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http://dx.doi.org/10.1186/s12866-020-01824-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247253PMC

Association between Helicobacter Pylori infection and stroke: a meta-analysis of 273,135 patients.

J Neurol 2020 May 23. Epub 2020 May 23.

Department of Neurology, University of Texas Rio Grande Valley, Valley Baptist Medical Center, Harlingen, TX, USA.

Background: Stroke stands among the most leading causes of mortality worldwide. Although modifiable risk factors for stroke have been identified, current risk factors do not sufficiently explain the risk in young patients. Previous studies have postulated an association between infection by Helicobacter pylori (HP) and stroke. Read More

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http://dx.doi.org/10.1007/s00415-020-09933-xDOI Listing

Contrasting serum biomarker profiles in two Colombian populations with different risks for progression of premalignant gastric lesions during chronic Helicobacter pylori infection.

Cancer Epidemiol 2020 May 21;67:101726. Epub 2020 May 21.

Division of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, MA, USA; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA. Electronic address:

Background: Colombians in coastal Tumaco have a lower incidence of Helicobacter pylori-associated gastric cancer compared to individuals from Tuquerres in the high Andes. This is despite nearly universal prevalence of H. pylori infection and chronic gastritis. Read More

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http://dx.doi.org/10.1016/j.canep.2020.101726DOI Listing

Serology Is More Sensitive Than Urea Breath Test or Stool Antigen for the Initial Diagnosis of Helicobacter pylori Gastritis When Compared With Histopathology.

Am J Clin Pathol 2020 May 23. Epub 2020 May 23.

Department of Laboratory Medicine, University of Washington, Seattle.

Objectives: To assess the concordance and performance characteristics of Helicobacter pylori laboratory tests compared with histopathology and to propose algorithms for the diagnosis of H pylori that minimize diagnostic error.

Methods: H pylori diagnostics were reviewed from a 12-year period within a health system (2,560 cases). Analyses were performed to adjust diagnostic performance based on treatment and consensus histopathologic diagnoses among pathologists. Read More

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http://dx.doi.org/10.1093/ajcp/aqaa043DOI Listing

Utility of dried blood spots in detecting infection.

Indian J Med Microbiol 2019 Oct-Dec;37(4):514-520

Centre for Cancer Epidemiology, Advanced Centre for Treatment Research and Education in Cancer, Tata Memorial Centre; Homi Bhabha National Institute (HBNI), Training School Complex, Anushaktinagar, Mumbai, Maharashtra, India.

Purpose: Identifying infectious pathogens by collecting intravenous blood (IVB) is a well-established procedure, however, the collection of IVB in field epidemiological study is challenging. The dried blood spot (DBS) as an alternative to IVB has been introduced, although, there is a limited study to demonstrate the utility of DBS stored at various storage conditions and transported at different periods. This is an observational study, which evaluates the effectiveness of DBS in field epidemiological studies to identify infectious pathogens. Read More

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http://dx.doi.org/10.4103/ijmm.IJMM_19_441DOI Listing

Changes in the severity of gastric mucosal inflammation associated with Helicobacter pylori in humans coinfected with  intestinal helminths.

Indian J Gastroenterol 2020 May 20. Epub 2020 May 20.

Laboratorio de Enfermedades del Sistema Inmune y Oncológicas, Departamento de Medicina, Universidad de Alcalá, Madrid, Spain.

Background: Though a few studies in animal models suggest that intestinal helminths (IH) favorably affect evolution of gastritis associated with Helicobacter pylori (H. pylori) the studies supporting this concept in humans are only a few and are based on serological data.

Methods: To evaluate the possible influence of IH on the human gastric mucosa, three groups of Venezuelan adults with gastropathy (endoscopically diagnosed) were studied: H. Read More

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http://dx.doi.org/10.1007/s12664-020-01023-0DOI Listing

Type IV secretion of CagA into oral epithelial cells is prevented by the absence of CEACAM receptor expression.

Gut Pathog 2020 14;12:25. Epub 2020 May 14.

1Department of Biology, Division of Microbiology, Friedrich Alexander University Erlangen, Staudtstrasse 5, 91058 Erlangen, Germany.

Background: typically colonizes the human stomach, but it can occasionally be detected in the oral cavity of infected persons. Clinical outcome as a result of gastric colonization depends on presence of the pathogenicity island PAI that encodes a type-IV secretion system (T4SS) for translocation of the effector protein CagA and ADP-heptose. Upon injection into target cells, CagA is phosphorylated, which can be demonstrated by in vitro infection of the gastric epithelial cell line AGS, resulting in cell elongation. Read More

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http://dx.doi.org/10.1186/s13099-020-00363-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7222478PMC

Susceptibility-guided therapy for Helicobacter pylori-infected penicillin-allergic patients: A prospective clinical trial of first-line and rescue therapies.

Helicobacter 2020 May 19:e12699. Epub 2020 May 19.

Division of Gastroenterology and Hepatology, Key Laboratory of Gastroenterology and Hepatology, Ministry of Health, Shanghai Institute of Digestive Disease, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.

Background: Helicobacter pylori (H pylori) treatment remains a challenge for penicillin-allergic patients.

Aim: To evaluate the efficacy and tolerability of susceptibility-guided first-line and rescue treatment in H pylori-infected penicillin-allergic patients.

Methods: Consecutive H pylori-infected patients with penicillin allergy received a 14-day triple or quadruple therapy based on susceptibility to clarithromycin, levofloxacin, and metronidazole. Read More

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http://dx.doi.org/10.1111/hel.12699DOI Listing

Evaluation of the Allplex™ H pylori and ClariR PCR Assay for Helicobacter pylori detection on gastric biopsies.

Helicobacter 2020 May 19:e12702. Epub 2020 May 19.

Hôpital Pellegrin, French National Reference Centre for Campylobacters & Helicobacters, Bordeaux, France.

Background: The diagnosis of Helicobacter pylori infection can be made by PCR on gastric biopsies. The objective of this study was to evaluate retrospectively the performance of the Allplex™ H pylori and ClariR PCR Assay (Seegene).

Material And Methods: A collection of 180 DNA samples extracted from gastric biopsies was used in this study: 90 DNAs from H pylori-negative patients and 90 from H pylori-positive patients. Read More

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http://dx.doi.org/10.1111/hel.12702DOI Listing

Letter: Helicobacter pylori infection and its role in oesophageal adenocarcinoma.

Aliment Pharmacol Ther 2020 Jun;51(11):1215-1216

Department of Internal Medicine, Second Medical Clinic, Ippokration Hospital, Aristotle University of Thessaloniki, Thessaloniki, Macedonia, Greece.

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http://dx.doi.org/10.1111/apt.15747DOI Listing

Marginal ulceration following Roux-en-Y gastric bypass: risk factors for ulcer development, recurrence and need for revisional surgery.

Surg Endosc 2020 May 18. Epub 2020 May 18.

Division of General Surgery, University Health Network, Toronto, ON, Canada.

Background: Marginal ulcer formation is a known complication following RYGB. While most respond to medical therapy, many patients have recurrent or chronic MU. Although non-steroidal anti-inflammatory drug (NSAID) use, smoking and Helicobacter pylori infection are known risk factors of MU, little is known about what increases the likelihood of developing recalcitrant ulcers. Read More

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http://dx.doi.org/10.1007/s00464-020-07650-0DOI Listing

Association analysis between SNPs in LATS1 and LATS2 and non-cardia gastric cancer.

BMC Gastroenterol 2020 May 18;20(1):155. Epub 2020 May 18.

Inner Mongolia Institute of Digestive Diseases, The Second Affiliated Hospital of Baotou Medical College, 30 Hudemulin Street, Baotou, 014030, Inner Mongolia, China.

Background: Many studies have found that large tumor suppressor kinase 1 (LATS1) and LATS2 play important roles in many diseases, but studies have been rare on the relationship between these genes and non-cardia gastric cancer (GC). We performed a case-control association study to investigate the associations between single nucleotide polymorphisms (SNPs) in LATS1 and LATS2 genes and Helicobacter pylori (H. pylori) infection as well as the risk of non-cardia GC. Read More

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http://dx.doi.org/10.1186/s12876-020-01250-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7236108PMC

Association between Helicobacter pylori and otitis media with effusion in children: A systematic review.

Int J Pediatr Otorhinolaryngol 2020 May 8;135:110091. Epub 2020 May 8.

Department of Otorhinolaryngology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China. Electronic address:

Background: Studies have shown that Helicobacter pylori (H. pylori) infection may be associated with the occurrence of otitis media with effusion (OME) in children.

Objective: This is a systematic review of the relevant published literature to explore the relationship between H. Read More

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http://dx.doi.org/10.1016/j.ijporl.2020.110091DOI Listing

A systematic review and meta-analysis of the prevalence of Helicobacter pylori in patients with diabetes.

Diabetes Metab Syndr 2020 May 11;14(4):601-607. Epub 2020 May 11.

Department of Epidemiology, School of Public Health, Iran University of Medical Sciences, Tehran, Iran; Social Determinants of Health Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, Iran. Electronic address:

Background And Aims: Prior studies have shown that Helicobacter pylori (H. Pylori) has the important role in the development of gastrointestinal diseases and diabetes in patients with diabetes. Due to the contradictory results on the prevalence of H. Read More

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http://dx.doi.org/10.1016/j.dsx.2020.05.009DOI Listing

Sporadic pyloric gland adenoma associated with a large fundic gland polyp: genetic evidence for stepwise progression.

Gastric Cancer 2020 May 15. Epub 2020 May 15.

Division of Diagnostic Pathology, National Cancer Center Hospital, 5-1-1, Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.

Pyloric gland adenoma (PGA) is an uncommon variant of gastric adenoma exhibiting pyloric gland/mucous neck cell differentiation. We present a sporadic PGA associated with a large fundic gland polyp (FGP) in a woman in her 40 s without Helicobacter pylori infection. The polyp, measuring 25 mm in size, was located in the middle gastric body and was removed by endoscopic submucosal dissection. Read More

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http://dx.doi.org/10.1007/s10120-020-01082-4DOI Listing

Bacterial infection and non-Hodgkin's lymphoma.

Crit Rev Microbiol 2020 May 15:1-18. Epub 2020 May 15.

Aix-Marseille University, IRD, APHM, MEPHI, Marseille, France.

One quarter of all cancers are linked to infectious diseases. The link between viral infection and cancer has been widely studied, but few reports have focused on the carcinogenic role of bacterial infection. Nonetheless, , , , and are bacteria that can be associated with non-Hodgkin's lymphoma (NHL), the most common haematologic malignancy. Read More

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http://dx.doi.org/10.1080/1040841X.2020.1760786DOI Listing

Nonalcoholic Fatty Liver Disease Is Associated with Infection in North Urban Chinese: A Retrospective Study.

Gastroenterol Res Pract 2020 25;2020:9797841. Epub 2020 Jan 25.

Department of Laboratorial Science and Technology, School of Public Health, Peking University, Beijing 100191, China.

Background: The association between nonalcoholic fatty liver disease (NAFLD) and () is controversial. We conducted a retrospective study to clarify the seroprevalence of infection and the relationship between NAFLD and infection in north urban Chinese.

Methods: The retrospective study was performed at Aerospace Center Hospital in Beijing. Read More

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http://dx.doi.org/10.1155/2020/9797841DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204187PMC
January 2020

Optimized diagnosis of and tailored eradication therapy for preventing gastric cancer: a proposal for SHAKE strategy.

Expert Rev Gastroenterol Hepatol 2020 May 31:1-11. Epub 2020 May 31.

Department of Pathology, Soonchunhyang University Hospital , Seoul, Korea.

Introduction: To decrease gastric cancer-related mortality, the Korean National Cancer Screening Program provides biennial screening gastroscopy to all individuals aged >40 years. However, a test-and-treat strategy of for preventing gastric cancer has not been established.

Areas Covered: In this review, we present up-to-date results of endoscopic findings of gastritis, optimal sites for detection, gastric cancer risk assessment using serum pepsinogen, tailored eradication based on the antimicrobial resistance against , and post-eradication surveillance. Read More

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http://dx.doi.org/10.1080/17474124.2020.1770594DOI Listing

Persistent infection of Helicobacter pylori affects weight loss in obese population compared with persistent negative: A case-control study based on healthy Chinese.

Helicobacter 2020 May 15:e12697. Epub 2020 May 15.

Health Management Center, Taizhou Hospital, Linhai, China.

Background: The relationship between Helicobacter pylori (H pylori) and body mass index (BMI) is still inconclusive. Not only the high rate of H pylori infection but also the increasing higher BMI levels are endangering Chinese today.

Methods: The aim of this research was to evaluate the association between different situations of H pylori infection and BMI values or levels in Chinese healthy population. Read More

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http://dx.doi.org/10.1111/hel.12697DOI Listing