125 results match your criteria Heart international[Journal]


Role of Optimal Medication Given to Patients with Hypertension and Ischemic Heart Disease Prior to an Acute Coronary Syndrome.

Heart Int 2017 Jan-Dec;12(1). Epub 2017 Oct 14.

Cardiology Clinic, "St. Spiridon" County Emergency Hospital, University of Medicine and Pharmacy "Grigore T. Popa", Iași - Romania.

Introduction: Administering optimal cardiovascular medication (OCM) to patients with hypertension (HBP) and ischemic heart disease (IHD) lowers cardiovascular morbidity and mortality.The main objective of this study was to compare in-hospital cardiac mortality among patients with HBP and/or IHD, treated or untreated with OCM, who developed a first episode of acute coronary syndrome (ACS).

Methods: The study was carried out retrospectively and included patients admitted with a first episode of ACS between 2013 and 2016. Read More

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http://dx.doi.org/10.5301/heartint.5000237DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6159667PMC
October 2017
1 Read

Placement Of Cardiac PacemaKEr Trial (POCKET) - rationale and design: a randomized controlled trial.

Heart Int 2017 Jan-Dec;12(1):e8-e11. Epub 2017 Apr 14.

Centre for Research and Development, Uppsala University/Region Gävleborg, Gävle - Sweden.

Background: A pacemaker system consists of one or two leads connected to a device that is implanted into a pocket formed just below the collarbone. This pocket is typically subcutaneous, that is, located just above the pectoral fascia. Even though the size of pacemakers has decreased markedly, complications due to superficial implants do occur. Read More

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http://dx.doi.org/10.5301/heartint.5000235DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421194PMC
April 2017
3 Reads

The inhibitory effects of polysaccharide peptides (PsP) of against atherosclerosis in rats with dyslipidemia.

Heart Int 2017 Jan-Dec;12(1):e1-e7. Epub 2017 Apr 12.

Department of Biomedicine, Faculty of Medicine, Brawijaya University, Malang, East Java - Indonesia.

Background: Atherosclerosis occurs as a result of low-density lipoprotein (LDL) deposits oxidation. Endothelial dysfunction is an early process of atherosclerosis. Restoring endothelial lining back to normal by endothelial progenitor cells (EPCs) is critical for slowing or reversing vascular disease progression. Read More

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http://journals.sagepub.com/doi/10.5301/heartint.5000234
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http://dx.doi.org/10.5301/heartint.5000234DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460693PMC
April 2017
6 Reads

Calculating the 30-day Survival Rate in Acute Myocardial Infarction: Should we Use the Treatment Chain or the Hospital Catchment Model?

Heart Int 2017 Jan-Dec;12(1). Epub 2017 Feb 12.

Department of Cardiology, University Hospital of North-Norway, Tromsø - Norway.

Introduction: Acute myocardial infarction (AMI) is a potentially deadly disease and significant efforts have been concentrated on improving hospital performance. A 30-day survival rate has become a key quality of care indicator. In Northern Norway, some patients undergoing AMI are directly transferred to the Regional Cardiac Intervention Center at the University Hospital of North Norway in Tromsø. Read More

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http://dx.doi.org/10.5301/heartint.5000238DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6159709PMC
February 2017

Atrial fibrillation management in older heart failure patients: a complex clinical problem.

Heart Int 2016 Jan-Dec;11(1):e41-e49. Epub 2016 Sep 22.

Cardiology1/CCU, San Camillo Hospital, Rome - Italy.

Background: Atrial fibrillation (AF) and heart failure (HF), two problems of growing prevalence as a consequence of the ageing population, are associated with high morbidity, mortality, and healthcare costs. AF and HF also share common risk factors and pathophysiologic processes such as hypertension, diabetes mellitus, ischemic heart disease, and valvular heart disease often occur together. Although elderly patients with both HF and AF are affected by worse symptoms and poorer prognosis, there is a paucity of data on appropriate management of these patients. Read More

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http://dx.doi.org/10.5301/heartint.5000230DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5079118PMC
September 2016
9 Reads

Influence diagram of physiological and environmental factors affecting heart rate variability: an extended literature overview.

Heart Int 2016 Jan-Dec;11(1):e32-e40. Epub 2016 Sep 16.

 Association of Research in Osteopathy in Quebec (AQRO), Montreal - Canada;  Departement of Physical Activity, Faculty of Sciences, University of Quebec in Montreal (UQÀM), Montreal - Canada.

Heart rate variability (HRV) corresponds to the adaptation of the heart to any stimulus. In fact, among the pathologies affecting HRV the most, there are the cardiovascular diseases and depressive disorders, which are associated with high medical cost in Western societies. Consequently, HRV is now widely used as an index of health. Read More

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http://journals.sagepub.com/doi/10.5301/heartint.5000232
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http://dx.doi.org/10.5301/heartint.5000232DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056628PMC
September 2016
9 Reads

Seasonal variation of daily physical activity in individuals with heart failure.

Heart Int 2016 Jan-Dec;11(1):e25-e31. Epub 2016 Sep 3.

Department of Physical Therapy, Grand Valley State University, Grand Rapids - USA.

Background: Previous studies indicate that seasonal variation affects daily physical activity (PA), but none have investigated this relationship in individuals with heart failure (HF) who also have implanted cardioverter defibrillators and cardiac resynchronization therapy (ICD/CRT) devices. The purpose of the present study was to determine if seasonal variation in temperature affects daily PA in patients with HF and ICD/CRTs.

Patients And Methods: Secondary analysis of data from 16 subjects with HF and Medtronic® ICD/CRT devices enrolled in a randomized trial investigating interventions to improve daily PA. Read More

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http://dx.doi.org/10.5301/heartint.5000231DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5079117PMC
September 2016
2 Reads

Drug-eluting stents appear superior to bare metal stents for vein-graft PCI in vessels up to a stent diameter of 4 mm.

Heart Int 2016 Jan-Dec;11(1):e17-e24. Epub 2016 May 12.

Department of Cardiology, Barts Heart Centre, Barts Health NHS Trust, London - UK; NIHR Cardiovascular Biomedical Research Unit, Barts Heart Centre, Barts Health NHS Trust, London - UK.

Background: Research trials have shown improved short-term outcome with drug-eluting stents (DES) over bare metal stents (BMS) in saphenous vein graft (SVG) percutaneous coronary intervention (PCI), primarily by reducing target vessel revascularization (TVR) for in-stent restenosis. We compared the outcomes in patients undergoing SVG stent implantation treated with DES or BMS. In exploratory analyses we investigated the influence of stent generation and diameter. Read More

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http://dx.doi.org/10.5301/heartint.5000228DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5072290PMC
May 2016
14 Reads

Combined administration of the GPVI-Fc fusion protein Revacept with low-dose thrombolysis in the treatment of stroke.

Heart Int 2016 Jan-Dec;11(1):e10-e16. Epub 2016 Apr 25.

 AdvanceCOR GmbH - Procorde, Martinsried - Germany.

Background: Thrombolytic therapy with recombinant tissue plasminogen activator (rtPA) remains the only approved medication for acute ischemic stroke, but incurs significant bleeding risks. Therefore, approaches to combine lower doses of thrombolytic therapy with other effective drugs aim at improving efficacy and reducing bleeding rates. We examined the safety and therapeutic effects of various dosings of rtPA, either alone or combined with glycoprotein VI-Fc fusion protein (GPVI-Fc, Revacept) on experimental stroke in mice. Read More

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http://dx.doi.org/10.5301/heartint.5000229DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5072291PMC
April 2016
26 Reads

Circulating miR-126 and miR-499 reflect progression of cardiovascular disease; correlations with uric acid and ejection fraction.

Heart Int 2016 Jan-Dec;11(1):e1-e9. Epub 2016 Apr 26.

Department of Clinical Biochemistry and Molecular Biology, School of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd - Iran.

Background: The aim of this study was to assess plasma levels of endothelium- and heart-associated microRNAs (miRNAs) miR-126 and miR-499, respectively, using quantitative reverse transcriptase polymerase chain reaction.

Methods: A two-step analysis was conducted on 75 patients undergoing off-pomp coronary artery bypass graft (CABG) surgery. Five biomarkers of inflammation and cardiac injury were assessed in addition to the above-mentioned miRNAs. Read More

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http://dx.doi.org/10.5301/heartint.5000226DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056629PMC
April 2016
11 Reads

Differences in coronary artery blood velocities in the setting of normal coronary angiography and normal stress echocardiography.

Heart Int 2015 Jan-Dec;10(1):e6-e11. Epub 2016 Feb 18.

Department of Cardiology, Bnai Zion Medical Center, Haifa - Israel; Technion, Israel Institute of Technology, Haifa - Israel.

Background: Normal left anterior descending (LAD) coronary artery as determined by coronary angiography is considered not only to reflect normal angiography but also to correlate with normal anatomy and function. However, subjects who undergo coronary angiography may differ from those who do not need to have invasive evaluation even if their functional noninvasive studies like dobutamine stress echocardiography (DSE) were normal.

Aim: LAD velocities in subjects with normal angiography and those with normal DSE are equal. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946382PMC
http://dx.doi.org/10.5301/heartint.5000221DOI Listing
September 2016
2 Reads

Aspiration thrombectomy in a case of acute myocardial infarction due to coronary emboli in a patient with peripartum cardiomyopathy and mural thrombus.

Heart Int 2015 Jan-Dec;10(1):e25-7. Epub 2016 Feb 18.

Department of Cardiology, Louisiana State University Medical Center, Shreveport, Louisiana - USA.

Acute coronary syndrome (ACS) due to embolic phenomenon in the setting of peripartum cardiomyopathy (PPCM) and left ventricular mural thrombus is a rare occurrence. There have been two known cases described in medical literature. We present a unique case in which catheter-based aspiration thrombectomy was used to successfully treat a patient with ACS due to coronary emboli in the setting of PPCMand left ventricular mural thrombus. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946383PMC
http://dx.doi.org/10.5301/heartint.5000225DOI Listing
September 2016
3 Reads

Effectiveness of the CardioPain initiative in reducing inappropriate NSAID prescriptions in pain therapy among high cardiovascular risk patients: an informative Italian survey.

Heart Int 2015 Jan-Dec;10(1):e20-4. Epub 2016 Feb 18.

Cardiology Department CCU, Roccadaspide Hospital, Salerno - Italy.

Aims: Non-steroidal anti-inflammatory drugs (NSAIDs) and COX-2 inhibitors (COXIBs) may be associated with increased cardiovascular (CV) risk and mortality in CV patients. After the release of Note 66 by Agenzia Italiana del Farmaco (AIFA) to reduce inappropriate prescribing of NSAIDs and COXIBs, the CARDIOPAIN initiative was started in Italy to include such recommendations into the hospital discharge letter of patients with high CV risk. We evaluated the effect of the CARDIOPAIN initiative on the prescription of analgesic drugs by general practitioners (GPs). Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946381PMC
http://dx.doi.org/10.5301/heartint.5000227DOI Listing
September 2016
3 Reads

Yield of contemporary clinical strategies to detect patients with obstructive coronary artery disease.

Heart Int 2015 Jan-Dec;10(1):e12-9. Epub 2016 Feb 18.

Cardiology Department, Santa Marta Hospital, Centro Hospitalar de Lisboa Central, Lisbon - Portugal.

Purpose: Noninvasive ischemia testing (NIST) is recommended for most patients suspected to have stable coronary artery disease (CAD) before invasive coronary angiography (ICA). We sought to assess the diagnostic predictive ability of NIST over clinical risk profiling in a contemporary sample of patients undergoing the currently recommended diagnostic triage strategy.

Methods: From 2006 to 2011, 2,600 consecutive patients without known CAD undergoing elective ICA in a single tertiary-care center were retrospectively identified and the prevalence of obstructive CAD determined. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946384PMC
http://dx.doi.org/10.5301/heartint.5000224DOI Listing
September 2016
10 Reads

Short-term adjusted outcomes for heart failure.

Heart Int 2015 Jan-Dec;10(1):e1-5. Epub 2016 Feb 18.

Health Services Research Laboratory, University of Siena, Siena - Italy; Post Graduate School of Public Health, University of Siena, Siena - Italy.

Purpose: Heart failure (HF) is recognized as a major problem in industrialized countries. Short-term adjusted outcomes are indicators of quality for care process during/after hospitalization. Our aim is to evaluate, for patients with principal diagnosis of HF, in-hospital mortality and 30-day readmissions for all-causes using two different risk adjustment (RA) tools. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946385PMC
http://dx.doi.org/10.5301/heartint.5000220DOI Listing
September 2016
10 Reads

Use of a "CNI holidays" strategy in acute renal dysfunction late after heart transplant. Report of two cases.

Heart Int 2014 Jul-Dec;9(2):74-7. Epub 2014 Sep 1.

Department of Cardiology, La Fe University Hospital Valencia, Valencia - Spain.

Background: Acute renal dysfunction (ARD) may appear in heart transplant (HTx) patients both in the early postoperative period and during follow-up, even after several years. CD25 is a subunit of the interleukin-2 receptor which is found exclusively on activated CD4 T lymphocytes. CD25 is crucial for clonal expansion of anti-allograft host lymphocytes that mediate in acute rejection. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774950PMC
March 2016
5 Reads

Ranolazine preserves and improves left ventricular ejection fraction and autonomic measures when added to guideline-driven therapy in chronic heart failure.

Heart Int 2014 Jul-Dec;9(2):66-73. Epub 2014 Dec 22.

Department of Cardiology, Drexel University College of Medicine, and ANSAR Medical Technologies, Inc., Philadelphia, PA - USA.

Background: Ranolazine (RAN) reduces cardiac sodium channel 1.5's late sodium current in congestive heart failure (CHF), reducing myocardial calcium overload, potentially improving left ventricular (LV) function. RAN blocks neuronal sodium channel 1. Read More

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http://dx.doi.org/10.5301/heartint.5000219DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774941PMC
March 2016
2 Reads

Ranolazine improves autonomic balance in heart failure when added to guideline-driven therapy.

Heart Int 2014 Jul-Dec;9(2):59-65. Epub 2014 Sep 23.

Autonomic Laboratory, Department of Cardiology, Drexel University College of Medicine, Philadelphia - USA; ANSAR Medical Technologies, Inc., Philadelphia - USA.

Background: The effect of ranolazine (RAN) on cardiac autonomic balance in congestive heart failure (CHF) was studied.

Methods: Fifty-four CHF patients were randomized to (1) open-label RAN (RANCHF) added to usual therapy vs. (2) usual therapy (NORANCHF). Read More

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http://dx.doi.org/10.5301/heartint.5000215DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774937PMC
March 2016
2 Reads

Heart valve surgery: EuroSCORE vs. EuroSCORE II vs. Society of Thoracic Surgeons score.

Heart Int 2014 Jul-Dec;9(2):53-8. Epub 2014 Sep 24.

Cardiothoracic Surgery Department, Aga Khan University Hospital, Stadium Road, Karachi - Pakistan.

Background: This is a validation study comparing the European System for Cardiac Operative Risk Evaluation (EuroSCORE) II with the previous additive (AES) and logistic EuroSCORE (LES) and the Society of Thoracic Surgeons' (STS) risk prediction algorithm, for patients undergoing valve replacement with or without bypass in Pakistan.

Patients And Methods: Clinical data of 576 patients undergoing valve replacement surgery between 2006 and 2013 were retrospectively collected and individual expected risks of death were calculated by all four risk prediction algorithms. Performance of these risk algorithms was evaluated in terms of discrimination and calibration. Read More

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http://dx.doi.org/10.5301/heartint.5000214DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774933PMC
March 2016
3 Reads

Cardiac autonomic testing and treating heart disease. "A clinical perspective".

Heart Int 2014 Jul-Dec;9(2):45-52. Epub 2014 Nov 19.

Drexel University College of Medicine and ANSAR Medical Technologies, Inc., Philadelphia, PA - USA.

Background: Coronary heart disease (CHD) is a major health concern, affecting nearly half the middle-age population and responsible for nearly one-third of all deaths. Clinicians have several major responsibilities beyond diagnosing CHD, such as risk stratification of patients for major adverse cardiac events (MACE) and treating risks, as well as the patient. This second of a two-part review series discusses treating risk factors, including autonomic dysfunction, and expected outcomes. Read More

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http://dx.doi.org/10.5301/heartint.5000216DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774951PMC
March 2016
2 Reads

Cardiac autonomic testing and diagnosing heart disease. "A clinical perspective".

Heart Int 2014 Jul-Dec;9(2):37-44. Epub 2014 Dec 5.

ANSAR Medical Technologies, Inc., Philadelphia, PA - USA.

Background: Coronary heart disease (CHD) is a major health concern, affecting nearly half the middle-age population and responsible for nearly one-third of all deaths. Clinicians have responsibilities beyond diagnosing CHD, including risk stratification of patients for major adverse cardiac events (MACE), modifying the risks and treating the patient. In this first of a two-part review, identifying risk factors is reviewed, including more potential benefit from autonomic testing. Read More

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http://dx.doi.org/10.5301/heartint.5000218DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774935PMC
March 2016
2 Reads

Marked prolongation of QRS duration after initiation of dronedarone therapy.

Heart Int 2014 Jan-Jun;9(1):33-5. Epub 2014 Aug 11.

Section of Electrophysiology, Division of Cardiology, Otto-von-Guericke University, University Hospital Magdeburg, Magdeburg - Germany.

Dronedarone is a relatively new antiarrhythmic drug and is held to be less proarrhythmic than comparable compounds, although its proarrhythmia potential in humans has not been sufficiently evaluated. We describe a so far unreported dronedarone effect, namely a significant alteration of both the morphology and the duration of the QRS complex on the electro cardiogram in a 41-year old patient with symptomatic paroxysmal atrial fibrillation. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774943PMC
March 2016
3 Reads

An unusual cause of ventricular tachycardia: Port-A-Cath fracture and embolization into the pulmonary artery.

Heart Int 2014 Jan-Jun;9(1):30-2. Epub 2014 Aug 11.

Division of Cardiology, St. Boniface Hospital, University of Manitoba, Winnipeg, Manitoba - Canada.

We describe the case of a patient with a previously placed Port-A-Cath who was admitted to hospital for new onset of non-flushing catheter and palpitations with ventricular tachycardia. A chest X-ray and a linogram showed a Port-A-Cath fracture and distal embolization into the right ventricle resulting in ventricular tachycardia. The catheter was removed percutaneously using a Goose Neck snare with no complications and resolution of the ventricular tachycardia. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774947PMC
March 2016
7 Reads

The double helix angiography of right coronary arteries: false lumen stenting of a type F right coronary artery spiral dissection with late recanalization of the true lumen and occlusion of the stented false lumen.

Heart Int 2014 Jan-Jun;9(1):26-9. Epub 2014 Aug 19.

Section of Cardiology, Department of Internal Medicine, University of Manitoba, Winnipeg, Manitoba - Canada.

Guide catheter induced dissection of coronary arteries is an uncommon, but serious complication of coronary angioplasty. Treatment can include emergent coronary artery bypass grafting to the affected vessel or percutaneous intervention including wiring the true lumen and exclusion stenting of the dissection flap to prevent further propagation. Detailed descriptions have been published of techniques of intentional passage of guide wires into the false lumen and reentry into the true lumen with chronic total occlusions. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774942PMC
March 2016
6 Reads

Intravenous sildenafil in right ventricular dysfunction with pulmonary hypertension following a heart transplant.

Heart Int 2014 Jan-Jun;9(1):22-5. Epub 2014 Aug 11.

Heart Failure and Transplantation Unit, Cardiology Department, University and Polytechnic Hospital La Fe, Valencia - Spain.

The objective of the present work is to describe the experience with intravenous (IV) sildenafil in heart transplant (HT) patients with reactive pulmonary hypertension (PH) who developed right ventricular dysfunction (RVD) in the immediate postoperative period. The first 5 patients who received IV sildenafil followinga HT are presented. The HTs took place between March 2011 and September 2012 in patients aged 37 to 64 years; all patients were male. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774940PMC
March 2016
21 Reads

Differential effects of adrenergic antagonists (Carvedilol vs Metoprolol) on parasympathetic and sympathetic activity: a comparison of clinical results.

Heart Int 2014 Jan-Jun;9(1):15-21. Epub 2014 Aug 22.

Research Director, Autonomic Laboratory, Department of Cardiology, Drexel University College of Medicine, Medical Director, ANSAR Medical Technologies, Inc., Philadelphia, PA - USA.

Background: Cardiovascular autonomic neuropathy (CAN) is recognized as a significant health risk, correlating with risk of heart disease, silent myocardial ischemia or sudden cardiac death. Beta-blockers are often prescribed to minimize risk.

Objectives: In this second of two articles, the effects on parasympathetic and sympathetic activity of the alpha/beta-adrenergic blocker, Carvedilol, are compared with those of the selective beta-adrenergic blocker, Metoprolol. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774939PMC
March 2016
7 Reads

Differential effects of adrenergic antagonists (Carvedilol vs Metoprolol) on parasympathetic and sympathetic activity: a comparison of measures.

Heart Int 2014 Jan-Jun;9(1):7-14. Epub 2014 Aug 22.

Research Director, Autonomic Laboratory, Department of Cardiology, Drexel University College of Medicine, Medical Director, ANSAR Medical Technologies, Inc., Philadelphia, PA - USA.

Background: Cardiovascular autonomic neuropathy (CAN) is recognized as a significant health risk. Specific and sensitive measures of CAN are needed for early identification and treatment to avoid complications, preferably in the preclinical state.

Objectives: In this first of two articles, the patient cohort is described and two measures of autonomic function are reviewed: the traditional heart rate variability (HRV)-alone method and the newer parasympathetic and sympathetic (P&S) Method. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774948PMC
March 2016
12 Reads

Nuclear stress perfusion imaging versus computed tomography coronary angiography for identifying patients with obstructive coronary artery disease as defined by conventional angiography: insights from the CorE-64 multicenter study.

Heart Int 2014 Jan-Jun;9(1):1-6. Epub 2014 Aug 11.

Division of Cardiology, Department of Medicine and Department of Epidemiology, Johns Hopkins University, Baltimore - USA.

We investigated the diagnostic accuracy of computed tomography angiography (CTA) versus myocardial perfusion imaging (MPI) for detecting obstructive coronary artery disease (CAD) as defined by conventional quantitative coronary angiography (QCA). Sixty-three patients who were enrolled in the CorE-64 multicenter study underwent CTA, MPI, and QCA imaging. All subjects were referred for cardiac catheterization with suspected or known coronary artery disease. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774949PMC
March 2016
3 Reads

Conservative management of chronic aortic dissection with underlying aortic aneurysm.

Heart Int 2013 15;8(1):e4. Epub 2013 Mar 15.

Mount Sinai Hospital , New York, NY, USA.

Aortic dissection is one of the most common aortic emergencies affecting around 2000 Americans each year. It usually presents in the acute state but in a small percentage of patients aortic dissections go unnoticed and these patients survive without any adequate therapy. With recent advances in medical care and diagnostic technologies, aortic dissection can be successfully managed through surgical or medical options, consequently increasing the related survival rate. Read More

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http://dx.doi.org/10.4081/hi.2013.e4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805168PMC
November 2013
5 Reads

Phenotypic patterns of right ventricular dysfunction: analysis by cardiac magnetic imaging.

Heart Int 2013 22;8(1):e3. Epub 2013 Jan 22.

Heart Failure and Transplantation Unit, Cardiology Department, Hospital Universitari i Politècnic La Fe , Valencia, Spain.

The aim of this study was to use magnetic resonance imaging (MRI) to classify the morphological changes and remodeling of the right ventricle (RV) that occur in different clinical situations and that have an impact on RV function. Most literature has traditionally focused on the left ventricle (LV) and as a result, few studies analyze RV behavior and remodeling. The study evaluated all cardiac MRI performed at our center from 2008 to 2010. Read More

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http://dx.doi.org/10.4081/hi.2013.e3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805167PMC
November 2013
27 Reads

Computer-aided analysis of 64-slice coronary computed tomography angiography: a comparison with manual interpretation.

Heart Int 2013 22;8(1):e2. Epub 2013 Jan 22.

Stony Brook University Medical Center , Stony Brook, NY, USA.

Coronary computed tomography angiography (CCTA) is increasingly used for the assessment of coronary heart disease (CHD) in symptomatic patients. Software applications have recently been developed to facilitate efficient and accurate analysis of CCTA. This study aims to evaluate the clinical application of computer-aided diagnosis (CAD) software for the detection of significant coronary stenosis on CCTA in populations with low (8%), moderate (13%), and high (27%) CHD prevalence. Read More

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http://dx.doi.org/10.4081/hi.2013.e2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805166PMC
November 2013
12 Reads

Potential role of coronary computed tomography-angiography for guiding perioperative cardiac management for non-cardiac surgery.

Heart Int 2013 Jan 22;8(1):e1. Epub 2013 Jan 22.

Hospitalist Program, Department of Medicine.

Perioperative cardiac events can be a major consequence of surgery. The American College of Cardiology Foundation/American Heart Association has set out guidelines to aid physicians in identifying patients at the highest risk for these events. The guidelines do recommend for some patients to undergo non-invasive cardiac stress testing for further risk stratification, but their sensitivity and specificity for predicting cardiac events is not optimal. Read More

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http://dx.doi.org/10.4081/hi.2013.e1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805165PMC
January 2013
3 Reads

Comparison of contrast enhanced magnetic resonance angiography with invasive cardiac catheterization for evaluation of children with pulmonary atresia.

Heart Int 2012 Jun 21;7(2):e9. Epub 2012 Jun 21.

Department of Cardiology, Tanta University Hospital, Tanta, Egypt; ; Department of Radiology, Academic Medical Center, Amsterdam;

Complete assessment of the source of pulmonary blood supply and delineation of the anatomy of pulmonary arteries are essential for the management and prognostic evaluation of pulmonary atresia (PA) patients. Invasive cardiac catheterization is considered the gold standard imaging modality to achieve this. We investigated the role of contrast enhanced magnetic resonance angiography (MRA) to evaluate the pulmonary blood supply and the anatomy of the pulmonary arteries and compared this with cardiac catheterization in children with PA. Read More

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http://dx.doi.org/10.4081/hi.2012.e9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3504308PMC
June 2012
12 Reads
2 Citations

Intra-atrial endothelial lesion resulting from transseptal puncture for catheter ablation of atrial fibrillation.

Heart Int 2012 Jun;7(2):e8

Otto-von-Guericke University, University Hospital Magdeburg, Division of Cardiology, Section of Electrophysiology, Magdeburg, Germany.

Thromboembolic events are known complications of left atrial ablation therapy. We describe a complication which may also lead to systemic thromboembolism that has not been reported so far: the formation of a moving structure attached to the fossa ovalis after an attempted transseptal puncture in a 66-year old patient with symptomatic paroxysmal atrial fibrillation. Read More

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http://journals.sagepub.com/doi/10.4081/hi.2012.e8
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http://dx.doi.org/10.4081/hi.2012.e8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3504307PMC
June 2012
3 Reads

Development of bioartificial myocardium by electrostimulation of 3D collagen scaffolds seeded with stem cells.

Heart Int 2012 Jun 18;7(2):e14. Epub 2012 Sep 18.

University Paris Descartes, Pompidou Hospital, Laboratory of Biosurgical Research (LRB), Paris;

Electrostimulation (ES) can be defined as a safe physical method to induce stem cell differentiation. The aim of this study is to evaluate the effectiveness of ES on bone marrow mesenchymal stem cells (BMSCs) seeded in collagen scaffolds in terms of proliferation and differentiation into cardiomyocytes. BMSCs were isolated from Wistar rats and seeded into 3D collagen type 1 templates measuring 25 × 25 × 6 mm. Read More

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http://downloads.hindawi.com/journals/crp/2011/806795.pdf
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http://www.heart-int.com/article/development-of-bioartificia
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http://dx.doi.org/10.4081/hi.2012.e14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3504306PMC
June 2012
7 Reads

The prognostic value of estimated glomerular filtration rate, amino-terminal portion of the pro-hormone B-type natriuretic peptide and parameters of cardiopulmonary exercise testing in patients with chronic heart failure.

Heart Int 2012 Jun 19;7(2):e13. Epub 2012 Jun 19.

Department of Nuclear Medicine, Academic Medical Center, University of Amsterdam;

The aim of this study was to evaluate the prognostic value of renal function in relation to amino-terminal portion of the pro-hormone B-type natriuretic peptide (NT-proBNP) and parameters of cardiopulmonary exercise testing in predicting mortality and morbidity in patients with moderate chronic heart failure (CHF). Sixty-one CHF patients were included in the study. Patients' characteristics were: age 64. Read More

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http://dx.doi.org/10.4081/hi.2012.e13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3504305PMC
June 2012
3 Reads

Overexpression of ABCG1 protein attenuates arteriosclerosis and endothelial dysfunction in atherosclerotic rabbits.

Heart Int 2012 Jun 25;7(2):e12. Epub 2012 Jun 25.

Corimmun GmbH, (Procorde GmbH) Martinsried, Germany.

The ABCG1 protein is centrally involved in reverse cholesterol transport from the vessel wall. Investigation of the effects of ABCG1 overexpression or knockdown in vivo has produced controversial results and strongly depended on the gene intervention model in which it was studied. Therefore, we investigated the effect of local overexpression of human ABCG1 in a novel model of vessel wall-directed adenoviral gene transfer in atherosclerotic rabbits. Read More

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http://dx.doi.org/10.4081/hi.2012.e12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3504304PMC
June 2012
3 Reads

Influence of image acquisition settings on radiation dose and image quality in coronary angiography by 320-detector volume computed tomography: the CORE320 pilot experience.

Heart Int 2012 Jun 25;7(2):e11. Epub 2012 Jun 25.

Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, MD, USA;

The objective of this study was to investigate the impact of image acquisition settings and patients' characteristics on image quality and radiation dose for coronary angiography by 320-row computed tomography (CT). CORE320 is a prospective study to investigate the diagnostic performance of 320-detector CT for detecting coronary artery disease and associated myocardial ischemia. A run-in phase in 65 subjects was conducted to test the adequacy of the computed tomography angiography (CTA) acquisition protocol. Read More

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http://dx.doi.org/10.4081/hi.2012.e11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3504303PMC
June 2012
5 Reads

Transulnar sheathless percutaneous coronary intervention during bivalirudin infusion in high-risk elderly female with non-ST segment elevation myocardial infarction.

Heart Int 2012 Jun 14;7(2):e10. Epub 2012 Jun 14.

Interventional Cardiology, Policlinico Casilino;

Due to the ageing population and raised life expectancy, elderly patients are increasingly referred for percutaneous coronary intervention (PCI) during acute coronary syndromes (ACS). Bleeding complications are not infrequent during ACS, occurring in 2-5% of patients with prognostic and economic consequences. In particular, periprocedural bleeding and vascular complications are associated with worse clinical outcome, prolonged hospital stay and increased short- and long-term mortality, especially in elderly patients with acute coronary syndromes. Read More

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http://dx.doi.org/10.4081/hi.2012.e10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3504302PMC
June 2012
3 Reads

A complex dissected chronic occlusion: targeted balloon dilatation of false lumen to access true lumen, combined localized subintimal tracking and re-entry, parallel wire, contralateral injection and a useful antegrade lumen re-entry technique.

Heart Int 2012 Feb 16;7(1):e7. Epub 2012 Mar 16.

St. Boniface General Hospital, University of Manitoba, Canada.

Chronic total occlusion (CTO) angioplasty is one of the most challenging procedures remaining for the interventional operator. Recanalizing CTOs can improve exercise capacity, symptoms, left ventricular function and possibly reduce mortality. Multiple strategies such as escalating wire, parallel wire, see-saw, contralateral injection, subintimal tracking and re-entry (STAR), retrograde wire techniques (controlled antegrade retrograde subintimal tracking, CART), reverse CART, confluent balloon, rendezvous in coronary, and other techniques have all been described. Read More

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http://dx.doi.org/10.4081/hi.2012.e7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366303PMC
February 2012
3 Reads

Physicians' acquaintance with a new procedure results in higher patient referral: experience of Kosovo in coronary angiography.

Heart Int 2012 Feb 17;7(1):e6. Epub 2012 Feb 17.

Department of Cardiology, University Clinical Center of Kosova, Prishtina and Cardiology Diagnostic Center-Diagnostika, Vushtrri, Kosovo.

Unlabelled: The first coronary angiography in Kosovo was completed in 2003. We analyzed coronary angiographies performed in our center from October 2003 until October 2009 divided into two 3-year periods.

The Aims Of Our Study Were: to compare the number of coronary angiographies completed in the two periods; to evaluate the prevalence of normal coronary angiographies diagnosed in the first period compared to the second period; and to assess the prevalence of advanced coronary artery disease in the first three years compared to the last three years. Read More

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http://dx.doi.org/10.4081/hi.2012.e6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366302PMC
February 2012
9 Reads

Correlation of pulse wave velocity with left ventricular mass in patients with hypertension once blood pressure has been normalized.

Heart Int 2012 Feb 9;7(1):e5. Epub 2012 Mar 9.

Department of Medicine, University of British Columbia, Vancouver, B.C., Canada.

Vascular stiffness has been proposed as a simple method to assess arterial loading conditions of the heart which induce left ventricular hypertrophy (LVH). There is some controversy as to whether the relationship of vascular stiffness to LVH is independent of blood pressure, and which measurement of arterial stiffness, augmentation index (AI) or pulse wave velocity (PWV) is best. Carotid pulse wave contor and pulse wave velocity of patients (n=20) with hypertension whose blood pressure (BP) was under control (<140/90 mmHg) with antihypertensive drug treatment medications, and without valvular heart disease, were measured. Read More

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http://dx.doi.org/10.4081/hi.2012.e5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366301PMC
February 2012
4 Reads

Cardiac tumors in a tertiary care cancer hospital: clinical features, echocardiographic findings, treatment and outcomes.

Heart Int 2012 Feb 13;7(1):e4. Epub 2012 Feb 13.

Department of Cardiology and.

Cardiac tumors are a rare entity, comprised of tumors with diverse histology and natural history. We report the clinical characteristics, echocardiograhic findings, therapy and outcome of 59 patients with primary and metastatic cardiac tumors. Our institutional echocardiogram data base from 1993 through 2005 was reviewed to identify patients diagnosed with intra-cardiac tumor. Read More

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http://dx.doi.org/10.4081/hi.2012.e4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366300PMC
February 2012
18 Reads

Antioxidant enzymes as potential targets in cardioprotection and treatment of cardiovascular diseases. Enzyme antioxidants: the next stage of pharmacological counterwork to the oxidative stress.

Heart Int 2012 Feb;7(1):e3

Institute of Experimental Cardiology, Russian Cardiology Research-and-Production Complex, Moscow, Russia.

The focus in antioxidant research is on enzyme derivative investigations. Extracellular superoxide dismutase (EC-SOD) is of particular interest, as it demonstrates in vivo the protective action against development of atherosclerosis, hypertension, heart failure, diabetes mellitus. The reliable association of coronary artery disease with decreased level of heparin-released EC-SOD was established in clinical research. Read More

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http://dx.doi.org/10.4081/hi.2012.e3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366299PMC
February 2012
3 Reads

Stress testing and non-invasive coronary angiography in patients with suspected coronary artery disease: time for a new paradigm.

Heart Int 2012 Feb 8;7(1):e2. Epub 2012 Feb 8.

Division of Cardiology, Johns Hopkins University, Baltimore, USA.

Diagnosis and management of coronary artery disease represents major challenges to our health care system, affecting millions of patients each year. Until recently, the diagnosis of coronary artery disease was possible only through cardiac catheterization and invasive coronary angiography. To avoid the risks of an invasive procedure, stress testing is often employed for an initial assessment of patients with suspected coronary artery disease, serving as a gatekeeper for cardiac catheterization. Read More

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http://dx.doi.org/10.4081/hi.2012.e2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366298PMC
February 2012
2 Reads

What is the role of intra-aortic balloon counterpulsation in acute myocardial infarction presenting without shock?

Heart Int 2012 Feb 6;7(1):e1. Epub 2012 Feb 6.

Cardiovascular Division, St Thomas' Hospital Campus, Kings College London, UK.

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http://dx.doi.org/10.4081/hi.2012.e1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366297PMC
February 2012
3 Reads

Triple vessel coronary artery disease presenting as a markedly positive stress electrocardiographic test and a negative SPECT-TL scintigram: a case of balanced ischemia.

Heart Int 2011 Sep 18;6(2):e22. Epub 2011 Nov 18.

The ACAP Program; St. Luke's - Roosevelt Hospital Center, Columbia University College of Physicians and Surgeons, New York, NY, USA.

The presence of false negative nuclear stress test in the settings of positive electrocardiographic changes is a very unusual phenomenon and is usually secondary to balanced ischemia of the myocardial segments evaluated by SPECT-TL. We present a case of an 81-year old post-menopausal female who presented to her primary care physician for evaluation of a 6-week dyspnea on exertion and was referred to our institution for exercise stress test with Thallium SPECT with the objective of ruling out coronary artery disease and identifying possible areas of myocardial ischemia. The resting electrocardiogram was unremarkable and stress test evaluation was made. Read More

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http://journals.sagepub.com/doi/10.4081/hi.2011.e22
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http://dx.doi.org/10.4081/hi.2011.e22DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282439PMC
September 2011
23 Reads

Riboflavin alleviates cardiac failure in Type I diabetic cardiomyopathy.

Heart Int 2011 Sep 22;6(2):e21. Epub 2011 Nov 22.

Department of Pathophysiology, Wannan Medical College, Wuhu, China.

Heart failure (HF) is a common and serious comorbidity of diabetes. Oxidative stress has been associated with the pathogenesis of chronic diabetic complications including cardiomyopathy. The ability of antioxidants to inhibit injury has raised the possibility of new therapeutic treatment for diabetic heart diseases. Read More

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http://dx.doi.org/10.4081/hi.2011.e21DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282438PMC
September 2011
3 Reads

Excimer laser coronary atherectomy in septal collaterals during retrograde recanalization of a chronic total occlusion.

Heart Int 2011 Sep 16;6(2):e20. Epub 2011 Dec 16.

Department of Cardiology, Zentralklinik Bad Berka, Bad Berka;

Management of chronic total occlusions has been refined through the development of a retrograde approach via collateral pathways. We describe here the use of excimer laser coronary atherectomy in the septal collaterals. This appraoch was not yet described in the literature. Read More

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http://dx.doi.org/10.4081/hi.2011.e20DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282437PMC
September 2011
2 Reads

Cardiac magnetic resonance imaging of a patient with an magnetic resonance imaging conditional permanent pacemaker.

Heart Int 2011 Sep 26;6(2):e19. Epub 2011 Oct 26.

Department of Cardiac Electrophysiology and.

Cardiac magnetic resonance imaging (MRI) is increasingly used as the optimum modality for cardiac imaging. An aging population and rising numbers of patients with permanent pacemakers means many such individuals may require cardiac MRI scanning in the future. Whilst the presence of a permanent pacemaker is historically regarded as a contra-indication to MRI scanning, pacemaker systems have been developed to limit any associated risks. Read More

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http://dx.doi.org/10.4081/hi.2011.e19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282436PMC
September 2011
2 Reads