2,637 results match your criteria Heart and vessels[Journal]


Liraglutide suppresses atrial electrophysiological changes.

Heart Vessels 2019 Feb 14. Epub 2019 Feb 14.

Department of Cardiovascular Medicine, Kitasato University School of Medicine, 1-15-1, Kitasato, Minami-ku, Sagamihara, Kanagawa, 252-0374, Japan.

We have shown that a dipeptidyl peptidase 4 (DPP-4) inhibitor suppresses atrial remodeling in a canine atrial fibrillation (AF) model. Glucagon-like peptide-1 (GLP-1) is increased by DPP-4 inhibitors. However, it is not clear whether GLP-1 is involved in the suppression of atrial remodeling. Read More

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http://dx.doi.org/10.1007/s00380-018-01327-4DOI Listing
February 2019
1 Read

Impacts of the body size on the left atrial wall thickness and atrial fibrillation recurrence after catheter ablation.

Heart Vessels 2019 Feb 8. Epub 2019 Feb 8.

Second Department of Internal Medicine, University of Toyama, 2630 Sugitani, Toyama, 930-0194, Japan.

The increased body size correlates with the occurrence of atrial fibrillation (AF); however, the impact of the body size on the AF recurrence after ablation remains unclear. We enrolled 283 AF patients (179 paroxysmal, 51 persistent, and 53 long-standing persistent) who received ablation and assessed the correlation between the body surface area (BSA) and the AF recurrence. Furthermore, we measured the left atrial wall thickness using computed tomography. Read More

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http://dx.doi.org/10.1007/s00380-019-01357-6DOI Listing
February 2019
1 Read

Linc00299/miR-490-3p/AURKA axis regulates cell growth and migration in atherosclerosis.

Heart Vessels 2019 Feb 8. Epub 2019 Feb 8.

Affiliated Hospital of Hebei University, No 212 Yuhua East Road, Baoding, 071000, Hebei, China.

Long non-coding RNA (lncRNA) plays a crucial role in regulating various cellular processes in atherosclerosis. The present study identified the regulation of Linc00299, via miR-490-3p targeting Aurora kinase A (AURKA), on migration and proliferation of endothelial cells and vascular smooth muscle cells (VSMCs) during atherosclerosis. The expression of RNAs was assessed by real-time PCR. Read More

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http://link.springer.com/10.1007/s00380-019-01356-7
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http://dx.doi.org/10.1007/s00380-019-01356-7DOI Listing
February 2019
3 Reads
2.109 Impact Factor

Effect of acute aerobic exercise on arterial stiffness and thyroid-stimulating hormone in subclinical hypothyroidism.

Heart Vessels 2019 Feb 6. Epub 2019 Feb 6.

Division of Clinical Laboratory Medicine, Hyogo College of Medicine, 1-1 Mukogawa-cho, Nishinomiya, 663-8501, Japan.

Acute exercise has been reported to increase thyroid hormone levels and decrease arterial stiffness in healthy young subjects. However, the effect of acute aerobic exercise on circulating thyroid hormone levels and arterial stiffness in patients with subclinical hypothyroidism remains unclear. The aim of this study was to investigate the effects of acute aerobic exercise on arterial stiffness and thyroid hormone levels, and any relationship between these endpoints, in patients with subclinical hypothyroidism. Read More

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http://dx.doi.org/10.1007/s00380-019-01355-8DOI Listing
February 2019
1 Read

Clinical characteristics and prognostic factors in acute coronary syndrome patients complicated with cardiogenic shock in Japan: analysis from the Japanese Circulation Society Cardiovascular Shock Registry.

Heart Vessels 2019 Feb 4. Epub 2019 Feb 4.

JCS Shock Registry Scientific Committee, Tokyo, Japan.

Cardiogenic shock frequently leads to death even with intensive treatment. Although the leading cause of cardiogenic shock is acute coronary syndrome (ACS), the clinical characteristics and the prognosis of ACS with cardiogenic shock in the present era still remain to be elucidated. We analyzed clinical characteristics and predictors of 30-day mortality in ACS with cardiogenic shock in Japan. Read More

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http://dx.doi.org/10.1007/s00380-019-01354-9DOI Listing
February 2019
2 Reads

The impact of intraday glucose variability on coronary artery spasm in patients with dysglycemia.

Heart Vessels 2019 Feb 2. Epub 2019 Feb 2.

Department of Cardio-Renal Medicine and Hypertension, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi, Mizuhocho, Nagoya, 4678601, Japan.

Impaired glucose metabolism is associated with an increased risk of cardiovascular complications, and coronary artery spasm is thought to underlie the development of coronary artery disease. Intraday glucose variability (GV) accelerates oxidative stress and inflammatory cytokine release, but its impact on coronary artery spasm remains unclear. This study investigated the relationship between intraday GV and coronary artery spasm. Read More

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http://link.springer.com/10.1007/s00380-019-01353-w
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http://dx.doi.org/10.1007/s00380-019-01353-wDOI Listing
February 2019
1 Read

A functional evaluation of cerebral perfusion for coronary artery bypass grafting patients.

Heart Vessels 2019 Jan 31. Epub 2019 Jan 31.

Division of Cardiac Surgery, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan.

We evaluate the utility of providing a pulsatile blood flow by applying off-pump coronary artery bypass grafting (CABG) or intra-aortic balloon pumping (IABP) with conventional CABG to prevent perioperative stroke in patients with cerebral hypoperfusion on single-photon emission-computed tomography (SPECT). A total of 286 patients underwent isolated CABG with a cerebral magnetic resonance angiography (MRA) evaluation between 2006 and 2015. Seventy-five had significant stenosis and/or occlusion of craniocervical vessels; the other 211 had no significant stenosis. Read More

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http://dx.doi.org/10.1007/s00380-019-01348-7DOI Listing
January 2019
2 Reads

Plaque modification and stabilization after paclitaxel-coated balloon treatment for de novo coronary lesions.

Heart Vessels 2019 Jan 30. Epub 2019 Jan 30.

Department of Internal Medicine and Cardiovascular Center, Seoul National University Hospital, Seoul, South Korea.

This study aimed to assess the healing response, as evidenced through temporal morphological and functional changes, following paclitaxel-coated balloon (PCB) treatment of de novo coronary lesions. This retrospective, observational study, included patients with significant de novo coronary lesions who were treated with PCB and had serial angiographic, intravascular ultrasound virtual histology (IVUS-VH), fractional flow reserve (FFR) measurements, and optical coherence tomography (OCT) performed before balloon angioplasty (BA), after BA, and at 9-month follow-up. A total of 20 patients (21 lesions) were included in this study. Read More

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http://dx.doi.org/10.1007/s00380-019-01346-9DOI Listing
January 2019
2 Reads
2.109 Impact Factor

Higher non-cardiac mortality and lesser impact of early revascularization in patients with type 2 compared to type 1 acute myocardial infarction: results from the Tokyo CCU Network registry.

Heart Vessels 2019 Jan 25. Epub 2019 Jan 25.

Tokyo CCU Network Scientific Committee, Tokyo, Japan.

As the definition of type 2 acute myocardial infarction (AMI) is obscure, the characteristics of this disease vary among studies. The clinical significance of type 2 AMI is unclear. We surveyed the Tokyo Cardiovascular Care Unit (CCU) Network registry between 2010 and 2014. Read More

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http://dx.doi.org/10.1007/s00380-019-01350-zDOI Listing
January 2019
1 Read
2.109 Impact Factor

Relationship between electrical conduction and phasic left atrial function: P-wave signal-averaged electrocardiography and time-left atrial volume curve assessments using two-dimensional speckle-tracking echocardiography.

Heart Vessels 2019 Jan 25. Epub 2019 Jan 25.

Gifu Municipal Hospital, Gifu, Japan.

P-wave signal-averaged electrocardiography (P-SAECG) can detect imperceptible conduction abnormalities, and volume analysis using two-dimensional speckle-tracking echocardiography (2-DSTE) allows us to easily measure the phasic function of the left atrium (LA). Both conduction abnormalities and functional deformation of the LA may be linked to the clinical outcome; however, the exact relationship is unclear. The aim of this study was to investigate the relationship between the phasic function of the LA and electrical conduction using P-SAECG and 2-DSTE. Read More

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http://dx.doi.org/10.1007/s00380-019-01351-yDOI Listing
January 2019

Improving outcomes in chronic obstructive pulmonary disease by taking beta-blockers after acute myocardial infarction: a nationwide observational study.

Heart Vessels 2019 Jan 24. Epub 2019 Jan 24.

Department of Critical Care Medicine, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.

β-Blockers are a standard therapy for acute myocardial infarction (AMI) due to their better short-term and long-term outcomes. However, β-blockers are often under-prescribed in chronic obstructive pulmonary disease (COPD) patients with AMI, since they are thought be related to bronchospasm. The aim of this study was to investigate the association between the usage of β-blockers and the risk of mortality in COPD patients after first AMI via a nationwide, population-based cohort study. Read More

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http://link.springer.com/10.1007/s00380-019-01341-0
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http://dx.doi.org/10.1007/s00380-019-01341-0DOI Listing
January 2019
8 Reads

Increase of chymase-dependent angiotensin II-forming activity in circulating mononuclear leukocytes after acute myocardial infarction chymase activity after acute myocardial infarction.

Heart Vessels 2019 Jan 24. Epub 2019 Jan 24.

Department of Cardiovascular Diseases, Fukuoka University Chikushi Hospital, 1-1-1 Zokumyoin, Chikushino-shi, Fukuoka, 818-8502, Japan.

A previous clinical study revealed elevation of chymase- and cathepsin G-dependent angiotensin II-forming activity (AIIFA) in the myocardium after acute myocardial infarction (AMI). This study examined the time course of chymase- and cathepsin G-dependent AIIFA in circulating mononuclear leukocytes (CML) after AMI. Consecutive patients with AMI were recruited. Read More

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http://dx.doi.org/10.1007/s00380-019-01352-xDOI Listing
January 2019

Validation of wearable textile electrodes for ECG monitoring.

Heart Vessels 2019 Jan 24. Epub 2019 Jan 24.

NTT Basic Research Laboratories, NTT Corporation, 3-1 Morinosato Wakamiya Atsugi, Kanagawa, 243-0198, Japan.

A highly conductive textile was woven from nano-fibers coated with the PEDOT-PSS polymer. The aim of this study was to assess the usefulness of textile electrodes for ECG recording as a smart garment. Electrode textile pads and lead wires were sewn to the lining of sportswear and their tolerability to repeated washings were tested up to 150 times. Read More

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http://dx.doi.org/10.1007/s00380-019-01347-8DOI Listing
January 2019

Effective blood hemoglobin level to predict prognosis in heart failure with preserved left ventricular ejection fraction: results of the Japanese heart failure syndrome with preserved ejection fraction registry.

Heart Vessels 2019 Jan 24. Epub 2019 Jan 24.

Department of Cardiovascular Medicine, Hokkaido University Graduate School of Medicine, Sapporo, Japan.

High prevalence of anemia in heart failure with preserved left ventricular ejection fraction (HFpEF) has been reported. However, little is known about the association of anemia and gender with prognosis in HFpEF patients. In addition, effective blood hemoglobin (Hb) level for prognosis in HFpEF patients remains largely unknown. Read More

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http://dx.doi.org/10.1007/s00380-019-01349-6DOI Listing
January 2019
1 Read

New insight into the intraventricular pressure gradient as a sensitive indicator of diastolic cardiac dysfunction in patients with childhood cancer after anthracycline therapy.

Heart Vessels 2019 Jan 23. Epub 2019 Jan 23.

Department of Pediatrics, Faculty of Medicine, Juntendo University, 3-1-1 Hongo, Bunkyo-ku, Tokyo, 113-8421, Japan.

Cardiac dysfunction due to cardiotoxicity from anthracycline chemotherapy is a leading cause of morbidity and mortality in survivors of childhood cancer. The intraventricular pressure gradient (IVPG) of the left ventricle (LV) is the suction force of blood from the left atrium to the LV apex during early diastole and is a sensitive indicator of diastolic function. We assessed IVPG as a new indicator of the cardiac dysfunction in survivors of childhood cancer after anthracycline therapy. Read More

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http://link.springer.com/10.1007/s00380-018-01332-7
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http://dx.doi.org/10.1007/s00380-018-01332-7DOI Listing
January 2019
2 Reads

Prognostic value of echocardiographic parameters for right ventricular function in patients with acute non-massive pulmonary embolism.

Heart Vessels 2019 Jan 22. Epub 2019 Jan 22.

Division of Cardiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.

A prognostic value of right ventricular (RV) systolic function assessed by echocardiography in patients with acute non-massive pulmonary embolism (PE) remains controversial. The hypothesis was RV free wall strain measured using speckle-tracking echocardiography might be a powerful prognostic factor in those patients. We aimed to evaluate the prognostic value of echocardiographic measurements of RV systolic function for clinical outcomes and to assess the correlation between the echocardiographic RV function parameters in patients with acute non-massive PE. Read More

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http://dx.doi.org/10.1007/s00380-019-01340-1DOI Listing
January 2019
1 Read

The effect of Telmisartan on the expression of connexin43 and neointimal hyperplasia in a rabbit iliac artery restenosis model.

Heart Vessels 2019 Jan 22. Epub 2019 Jan 22.

Tianjin Key Laboratory of Cardiovascular Remodeling and Target Organ Injury, Pingjin Hospital Heart Center, Affiliated Hospital of Logistics University of the Chinese People's Armed Police Forces, Tianjin, 300162, People's Republic of China.

We established a rabbit iliac artery restenosis model to explore the impact of Telmisartan on the expression of Connexin43 (Cx43) and neointimal hyperplasia. Thirty New Zealand white rabbits were randomly divided into three groups: control group (n = 10), restenosis group (n = 10), and Telmisartan group (n = 10). The restenosis model was established by high-cholesterol diet combined with double-balloon injury of iliac arteries. Read More

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http://dx.doi.org/10.1007/s00380-018-01338-1DOI Listing
January 2019
1 Read

U-shaped association of central pulse pressure with long-term prognosis after ST-segment elevation myocardial infarction.

Heart Vessels 2019 Jan 22. Epub 2019 Jan 22.

Department of Adult Cardiology, Deutsches Herzzentrum München, Technische Universität, Lazarettstrasse 36, 80636, Munich, Germany.

The relationship between central pulse pressure (CPP) measured at the time of primary percutaneous coronary intervention (PPCI) and long-term prognosis after ST-segment elevation myocardial infarction (STEMI) has not been investigated. CPP measurements were performed in 1348 patients with STEMI (327 women; mean age 62.5 ± 12. Read More

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http://dx.doi.org/10.1007/s00380-019-01344-xDOI Listing
January 2019
1 Read

Comparison of clinical outcomes between sufficient versus insufficient diagonal branch flow in anterior acute myocardial infarction.

Heart Vessels 2019 Jan 18. Epub 2019 Jan 18.

Division of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical University, 1-847 Amanuma-cho, Omiya-ku, Saitama, 330-8503, Saitama, Japan.

In primary percutaneous coronary intervention (PCI), revascularization to the main branch is considered to be more important than that to the side branch. The purpose of the present study was to compare in-hospital clinical outcomes between sufficient and insufficient diagonal flow in patients with anterior ST-elevation acute myocardial infarction. A total of 229 left anterior descending artery (LAD)-AMI with final Thrombolysis in Myocardial Infarction (TIMI)-3 LAD flow were included, and divided into the sufficient diagonal flow group (TIMI-3 diagonal flow: n = 170) and the insufficient diagonal flow group (TIMI ≤ 2 diagonal flow: n = 59). Read More

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http://dx.doi.org/10.1007/s00380-019-01343-yDOI Listing
January 2019
1 Read

Direct comparison of prognostic ability of cardiac biomarkers for cardiogenic stroke and clinical outcome in patients with stroke.

Heart Vessels 2019 Jan 17. Epub 2019 Jan 17.

Department of Cardiology, Pulmonology, and Nephrology, Yamagata University School of Medicine, 2-2-2 Iida-Nishi, Yamagata, 990-9585, Japan.

Despite many recent advances in medicine, cardiogenic stroke is still a health problem with a high mortality rate. Cardiac biomarkers have been reported to be useful indicators for cardiogenic stroke and subsequent cerebrovascular events. However, there are no data directly comparing the cardiac biomarkers in stroke patients. Read More

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http://link.springer.com/10.1007/s00380-019-01345-w
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http://dx.doi.org/10.1007/s00380-019-01345-wDOI Listing
January 2019
3 Reads

Coronary computed tomography angiography as a tool for long-term cardiovascular risk stratification in diabetic patients.

Heart Vessels 2019 Jan 11. Epub 2019 Jan 11.

Institut für Radiologie und Nuklearmedizin, Deutsches Herzzentrum München, Klinik an der Technischen Universität München, Lazarettstrasse 36, 80636, München, Germany.

Objectives of the study were to examine the long-term prognostic power of coronary computed tomography angiography (CCTA) to predict death or myocardial infarction in patients with diabetes mellitus (DM). The prognostic value of CCTA in diabetic patients has been confirmed for short- and intermediate follow-up durations. The slowly progressing nature of coronary artery disease (CAD), however, underlines the necessity to validate CCTA for longer observation periods in this high-risk population. Read More

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http://dx.doi.org/10.1007/s00380-018-01339-0DOI Listing
January 2019
1 Read

Cost-effectiveness for prevention of thromboembolism by anticoagulants in non-valvular atrial fibrillation: additional analysis from the Hokuriku-Plus AF Registry.

Heart Vessels 2019 Jan 5. Epub 2019 Jan 5.

Department of Cardiovascular and Internal Medicine, Kanazawa University Graduate School of Medicine, 13-1 Takara-machi, Kanazawa, Ishikawa, 920-8641, Japan.

Although benefits of direct oral anticoagulants (DOAC) for treatment of non-valvular atrial fibrillation (AF) were well demonstrated, few data exist regarding cost-effectiveness between DOAC and warfarin uses in real-world clinical practice. Therefore, we estimated total cost of treatment for AF by authorized cardiologists in Japan. We studied consecutive 617 anticoagulated non-valvular AF patients (418 men, mean age 68. Read More

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http://link.springer.com/10.1007/s00380-018-01333-6
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http://dx.doi.org/10.1007/s00380-018-01333-6DOI Listing
January 2019
1 Read

Plaque characteristics and slow flow during percutaneous coronary intervention of irregular protrusion by optical coherence tomography.

Heart Vessels 2019 Jan 4. Epub 2019 Jan 4.

Department of Cardiovascular Medicine, Toho University Faculty of Medicine, 6-11-1 Omorinishi, Ota-ku, Tokyo, 143-8541, Japan.

Irregular protrusion on optical coherence tomography (OCT) is associated with clinical events and target lesion revascularization. We investigated clinical and procedure characteristics, plaque characteristics, slow flow after stent implantation, and clinical outcomes with irregular protrusion using OCT. Eighty-four lesions in 76 patients undergoing OCT before percutaneous coronary intervention were evaluated. Read More

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http://dx.doi.org/10.1007/s00380-018-01335-4DOI Listing
January 2019
1 Read

MicroRNA-19b-1 reverses ischaemia-induced heart failure by inhibiting cardiomyocyte apoptosis and targeting Bcl2 l11/BIM.

Heart Vessels 2019 Jan 3. Epub 2019 Jan 3.

Department of Cardiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No 197 Ruijin 2nd Road, Shanghai, 200025, People's Republic of China.

Ischaemia induces cardiac apoptosis and leads to a loss of cardiac function and heart failure after myocardial infarction. MicroRNA-19b-1 (miR-19b-1), a key member of the miR-17/92 cluster, plays crucial roles in inhibiting apoptosis. However, the role of miR-19b-1 in ischaemia-induced heart failure remains unknown. Read More

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http://dx.doi.org/10.1007/s00380-018-01336-3DOI Listing
January 2019
2 Reads

Influence of chronic kidney disease on coronary plaque components in coronary artery disease patients with both diabetes mellitus and hypertension.

Heart Vessels 2019 Jan 3. Epub 2019 Jan 3.

Department of Cardiology, Fukuoka University School of Medicine, 7-45-1 Nanakuma Jonan-ku, Fukuoka, 814-0180, Japan.

Chronic kidney disease (CKD) is well known to be associated with an increased incidence of coronary artery disease (CAD). Diabetes mellitus (DM) and hypertension (HTN), both of which are traditional risk factors for CAD, are the two most common causes of CKD. However, the influence of CKD on coronary atherosclerosis in CAD patients who have both DM and HTN remains uncertain. Read More

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http://dx.doi.org/10.1007/s00380-018-01334-5DOI Listing
January 2019
2 Reads

Analysis of the preferable site and stability of rotational reentry: its role for the maintenance of atrial fibrillation.

Heart Vessels 2019 Jan 3. Epub 2019 Jan 3.

Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Kumamoto, 860-8556, Japan.

It remains unclear whether AF is maintained by rotor. We evaluated the significance of rotor during atrial fibrillation (AF). Prevalence, location, and stability of rotational reentry (RR) in the left atrium were clarified by endocardial non-contact mapping in 66 AF patients. Read More

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http://dx.doi.org/10.1007/s00380-018-01331-8DOI Listing
January 2019
1 Read

Can we rely on Danish? Real-world data on patients with nonischemic cardiomyopathy from the German Device Registry.

Heart Vessels 2019 Jan 3. Epub 2019 Jan 3.

Division of Electrophysiology, Department of Cardiovascular Medicine, University of Münster, Münster, Germany.

According to current guidelines prophylactic implantable cardioverter-defibrillator (ICD) therapy is recommended in patients with significantly impaired left ventricular systolic function. However, the recently published DANISH trial did not find a significantly lower long-term rate of death from any cause compared with usual clinical care in patients with non-ischemic cardiomyopathy. We investigated whether registry data from a multi-center 'real-life' registry on patients with non-ischemic cardiomyopathy are similar to this trial. Read More

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http://link.springer.com/10.1007/s00380-018-01337-2
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http://dx.doi.org/10.1007/s00380-018-01337-2DOI Listing
January 2019
7 Reads

Involvement of sphingosine-1-phosphate receptors 2/3 in IR-induced sudden cardiac death.

Heart Vessels 2019 Jan 2. Epub 2019 Jan 2.

Department of Forensic Biology, School of Forensic Medicine, Shanxi Medical University, Wenhua Street 55#, Jinzhong, 030619, Shanxi, China.

It has been demonstrated that S1P receptors affect heart ischaemia-reperfusion (IR) induced injury. However, whether S1P receptors affect IR-induced cardiac death has not been investigated. The aim of this paper is to demonstrate the role of S1P receptors in IR-induced cardiac death. Read More

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http://dx.doi.org/10.1007/s00380-018-01323-8DOI Listing
January 2019

Myocardial perfusion defect assessed by single-photon emission computed tomography and frontal QRS-T angle in patients with prior anterior myocardial infarction.

Heart Vessels 2019 Jan 2. Epub 2019 Jan 2.

Department of Cardiovascular Medicine, Hiroshima University Graduate School of Biomedical and Health Sciences, 1-2-3, Kasumi-cho, Minami-ku, Hiroshima, 734-8551, Japan.

The frontal QRS-T angle is one of the markers of ventricular repolarization. We sought to assess the effects of myocardial perfusion defect on QRS-T angle in patients with prior anterior myocardial infarction (MI). Seventy-one patients with prior anterior MI and 71 age- and sex-matched control subjects having no myocardial perfusion defect were selected. Read More

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http://dx.doi.org/10.1007/s00380-018-01330-9DOI Listing
January 2019

Effect of carvedilol on heart rate response to cardiopulmonary exercise up to the anaerobic threshold in patients with subacute myocardial infarction.

Heart Vessels 2019 Jan 2. Epub 2019 Jan 2.

Division of Cardiology, Department of Internal Medicine, St. Marianna University School of Medicine, 2-16-1 Sugao, Miyamae-ku, Kawasaki, Kanagawa, 216-8511, Japan.

Resting heart rate (HR) plus 20 or 30 beats per minute (bpm), i.e., a simplified substitute for HR at the anaerobic threshold (AT), is used as a tool for exercise prescription without cardiopulmonary exercise testing data. Read More

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http://dx.doi.org/10.1007/s00380-018-01326-5DOI Listing
January 2019
1 Read

High-sensitivity cardiac troponin decrease after percutaneous coronary intervention in patients with stable coronary artery disease.

Heart Vessels 2019 Jan 1. Epub 2019 Jan 1.

Division of Cardiovascular Medicine, Tsuchiura Kyodo General Hospital, 4-1-1, Otsuno, Tsuchiura, Ibaraki, Japan.

Baseline cardiac troponin is a strong predictor of major adverse cardiac events (MACE), and the high sensitive assay can provide risk stratification under the 99th percentile values. Currently, prognostic benefit of PCI has not been established in patients with stable coronary artery disease (CAD), and the influence on baseline troponin levels is unknown. This study aimed to investigate the impact of PCI on baseline high-sensitivity cardiac troponin-I (hs-cTnI) levels and the association with MACE incidence. Read More

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http://dx.doi.org/10.1007/s00380-018-01325-6DOI Listing
January 2019

Comparison of anti-inflammatory effects of rivaroxaban vs. dabigatran in patients with non-valvular atrial fibrillation (RIVAL-AF study): multicenter randomized study.

Heart Vessels 2019 Jan 1. Epub 2019 Jan 1.

Department of Medical Science and Cardiorenal Medicine, Yokohama City University Graduate School of Medicine, Yokohama, Japan.

Some experimental studies have shown that direct oral anticoagulants (DOACs) have anti-inflammatory effects. However, the interval changes in inflammatory markers in patients with non-valvular atrial fibrillation (AF) who receive DOACs remain unknown. Between July 2013 and April 2014, a total of 187 AF patients randomly assigned to receive rivaroxaban (n = 91) or dabigatran (n = 96) were assessed for eligibility. Read More

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http://dx.doi.org/10.1007/s00380-018-01324-7DOI Listing
January 2019

Associations between plasma nesfatin-1 levels and the presence and severity of coronary artery disease.

Heart Vessels 2019 Jan 1. Epub 2019 Jan 1.

Department of Cardiology, National Hospital Organization Tokyo Medical Center, 2-5-1 Higashigaoka, Meguro-ku, Tokyo, 152-8902, Japan.

Nesfatin-1 is a recently identified anorexigenic peptide mainly secreted from the brain and adipose tissue. Although nesfatin-1 may have pro-inflammatory and apoptotic properties, the association between plasma nesfatin-1 levels and coronary artery disease (CAD) has not been clarified yet. We investigated plasma nesfatin-1 levels in 302 patients undergoing elective coronary angiography. Read More

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http://dx.doi.org/10.1007/s00380-018-01328-3DOI Listing
January 2019

Mid-term outcomes of concomitant left atrial appendage closure and catheter ablation for non-valvular atrial fibrillation: a multicenter registry.

Heart Vessels 2019 Jan 1. Epub 2019 Jan 1.

Department of Cardiovascular, Atrial Fibrillation Center, Guangdong Cardiovascular Institute, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, People's Republic of China.

To investigate the safety and midterm outcome of concomitant left atrial appendage (LAA) closure and catheter ablation (CA) as a one-stage hybrid procedure for non-valvular atrial fibrillation (AF) in a multicenter registry. A total of 50 consecutive patients with symptomatic drug-resistant non-valvular AF with CHADS-VASc score ≥ 2 and contraindications for antithrombotic therapy were included in the prospectively established LAA closure registry, and underwent concomitant LAA closure (48 for WATCHMAN and 2 for ACP) and CA procedure (40 for radiofrequency and 10 for cryoballoon CA). Two cardiac tamponades, one peripheral vascular complications and one mild air embolism were observed during perioperative period. Read More

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http://link.springer.com/10.1007/s00380-018-1312-4
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http://dx.doi.org/10.1007/s00380-018-1312-4DOI Listing
January 2019
3 Reads

Association between valvuloarterial impedance after transcatheter aortic valve implantation and 2-year mortality in elderly patients with severe symptomatic aortic stenosis: the OCEAN-TAVI registry.

Heart Vessels 2019 Jan 1. Epub 2019 Jan 1.

Keio University School of Medicine, Tokyo, Japan.

Pre-procedural valvuloarterial impedance (Zva) is considered as a useful predictor of mortality in patients diagnosed as having severe aortic stenosis (AS) who undergo transcatheter aortic valve implantation (TAVI). However, the prognostic significance of post-procedural Zva remains unclear. We aimed to evaluate the prognostic significance of Zva after TAVI. Read More

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http://link.springer.com/10.1007/s00380-018-01329-2
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http://dx.doi.org/10.1007/s00380-018-01329-2DOI Listing
January 2019
3 Reads

Impact of dual antiplatelet therapy with adjusted-dose prasugrel on mid-term vascular response in patients undergoing elective percutaneous coronary intervention with everolimus-eluting stents.

Heart Vessels 2019 Jan 1. Epub 2019 Jan 1.

Division of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, 7-5-2, Kusunoki-cho, Chuo-ku, Kobe, 6500017, Japan.

The impact of dual antiplatelet therapy (DAPT) with adjusted-dose (3.75 mg/day) prasugrel for Japanese patients has not been fully investigated in terms of local arterial healing following the elective percutaneous coronary intervention (PCI). The ROUTE-01 elective study was a prospective, 12-center and single-arm registry that enrolled 123 patients who underwent elective PCI with everolimus-eluting stents (EESs) under DAPT with a combination of adjusted-dose prasugrel and aspirin. Read More

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http://link.springer.com/10.1007/s00380-018-1322-2
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http://dx.doi.org/10.1007/s00380-018-1322-2DOI Listing
January 2019
7 Reads

Cyclic peptide RD808 reduces myocardial injury induced by β-adrenoreceptor autoantibodies.

Heart Vessels 2018 Dec 15. Epub 2018 Dec 15.

Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Capital Medical University, No. 10 Xitoutiao, You An Men Wai, Beijing, 100069, China.

Autoantibodies against the second extracellular loop of β-adrenergic receptor (β-AA) have been shown to be involved in the development of cardiovascular diseases. Recently, there has been considerable interest in strategies to remove these autoantibodies, particularly therapeutic peptides to neutralize β-AA. Researchers are investigating the roles of cyclic peptides that mimic the structure of relevant epitopes on the β-AR-EC in a number of immune-mediated diseases. Read More

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http://link.springer.com/10.1007/s00380-018-1321-3
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http://dx.doi.org/10.1007/s00380-018-1321-3DOI Listing
December 2018
6 Reads
2.109 Impact Factor

A pharmacodynamics comparison of prasugrel and clopidogrel in patients undergoing hemodialysis.

Heart Vessels 2018 Dec 12. Epub 2018 Dec 12.

Division of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Japan.

Platelet reactivity in the presence of clopidogrel is deteriorated in patients undergoing hemodialysis (HD). However, the impact of residual platelet reactivity with prasugrel use in Japanese patients on HD remains unclear. This was a prospective, multi-center, single-arm study conducted to compare platelet reactivity of prasugrel 3. Read More

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http://dx.doi.org/10.1007/s00380-018-1313-3DOI Listing
December 2018

Impact of admission liver stiffness on long-term clinical outcomes in patients with acute decompensated heart failure.

Heart Vessels 2018 Dec 6. Epub 2018 Dec 6.

Department of Cardiovascular Medicine, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Kita-15 Nishi-7, kita-ku, Sapporo, Hokkaido, Japan.

Liver stiffness (LS) has been reported to be a marker of liver congestion caused by elevated central venous pressure in heart failure (HF) patients. Recent studies demonstrated that LS could be non-invasively measured by virtual touch quantification (VTQ). However, its prognostic implication in patients with acute decompensated heart failure (ADHF) is unclear. Read More

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http://link.springer.com/10.1007/s00380-018-1318-y
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http://dx.doi.org/10.1007/s00380-018-1318-yDOI Listing
December 2018
4 Reads

A single center's experience with total arterial revascularization and spiral aneurysmorrhaphy for ischemic cardiac disease.

Heart Vessels 2018 Dec 6. Epub 2018 Dec 6.

Department of Cardiac Surgery, Euroclinic of Athens, Athens, Greece.

The restoration of left ventricular (LV) geometry in combination with coronary artery bypass grafting for the treatment of ischemic cardiac disease remains controversial. We hereby present the experience of our center with total arterial myocardial revascularization (TAMR) and spiral aneurysmorrhaphy for ischemic heart disease. A retrospective analysis of 101 patients with advanced cardiovascular disease who underwent TAMR and spiral aneurysmorrhaphy was performed. Read More

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http://dx.doi.org/10.1007/s00380-018-1317-zDOI Listing
December 2018

Artificial FLOwering plants in Reducing Anxiety and depressive symptoms following Acute Coronary Syndromes (A-FLORA-ACS): a randomised controlled trial.

Heart Vessels 2018 Dec 11. Epub 2018 Dec 11.

MonashHeart, Monash Medical Centre, 246 Clayton Road, Clayton, VIC, 3168, Australia.

Patients often experience emotional distress after acute coronary syndrome (ACS). These may lead to symptoms of depression or anxiety and greater morbidity/mortality. We sought to determine whether flowering plants in the coronary care ward reduced depressive and anxiety symptoms in these patients. Read More

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http://link.springer.com/10.1007/s00380-018-1314-2
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http://dx.doi.org/10.1007/s00380-018-1314-2DOI Listing
December 2018
2 Reads

Comparison between instantaneous wave-free ratio versus morphometric assessments by intracoronary imaging.

Heart Vessels 2018 Dec 7. Epub 2018 Dec 7.

Division of Cardiology, Yokohama City University Medical Center, 4-57 Urafune-cho, Minami-ku, Yokohama, 232-0024, Japan.

Anatomical measurements obtained by intracoronary imaging devices are reported to correlate significantly with fractional flow reserve (FFR). Instantaneous wave-free ratio (iFR) is a nonhyperemic index of stenosis severity with discordant reports regarding its accuracy in relation to FFR. There is no information on the correlation of iFR with measurements derived from intracoronary imaging devices. Read More

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http://dx.doi.org/10.1007/s00380-018-1320-4DOI Listing
December 2018
1 Read

Chemokine (C-X-C motif) receptor 2 blockade by SB265610 inhibited angiotensin II-induced abdominal aortic aneurysm in Apo E mice.

Heart Vessels 2018 Dec 7. Epub 2018 Dec 7.

Department of Vascular Surgery, Peking Union Medical College Hospital, Beijing, 100005, People's Republic of China.

Inflammation plays a critical role in the development of abdominal aortic aneurysm (AAA). Chemokine receptor CXCR2 mediates inflammatory cell chemotaxis in several diseases. However, the role of CXCR2 in AAA and the underlying mechanisms remain unknown. Read More

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http://dx.doi.org/10.1007/s00380-018-1301-7DOI Listing
December 2018

Disease-specific characteristics of vascular cell adhesion molecule-1 levels in patients with peripheral artery disease.

Heart Vessels 2018 Dec 7. Epub 2018 Dec 7.

Department of Internal Medicine I, Friedrich Schiller University Jena, Jena, Germany.

Peripheral arterial disease (PAD) is one of the most common manifestations of systemic atherosclerosis. The prevalence of unrecognized PAD is high, leading to a lack of opportunity to detect subjects at a high risk for cardiovascular events. Inflammatory processes play an important role in the disease initiation as well as in the disease progression. Read More

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http://link.springer.com/10.1007/s00380-018-1315-1
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http://dx.doi.org/10.1007/s00380-018-1315-1DOI Listing
December 2018
13 Reads

Impact of decreased insulin resistance by ezetimibe on postprandial lipid profiles and endothelial functions in obese, non-diabetic-metabolic syndrome patients with coronary artery disease.

Heart Vessels 2018 Dec 5. Epub 2018 Dec 5.

Department of Cardiology, Iwate Prefectural Central Hospital, 1-4-1 Ueda, Morioka, 020-0066, Japan.

The association between insulin resistance and lipid dysmetabolism after consuming a meal is unclear. We aimed at assessing the effects of ezetimibe on postprandial hyperlipidemia and hyperinsulinemia and to find out whether the medication improves endothelial function in obese metabolic syndrome (MetS) patients with coronary artery disease (CAD). We obtained oral fat loading test results (4 and 6 h after load) and brachial flow-mediated vasodilation (FMD) measurements before and 24 weeks after ezetimibe treatment initiation from 27 MetS patients with CAD and from 68 control patients with CAD alone. Read More

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http://dx.doi.org/10.1007/s00380-018-1319-xDOI Listing
December 2018
1 Read

Diastolic wall strain as a predictor of age-related cardiovascular events in patients with preserved left ventricular ejection fraction.

Heart Vessels 2018 Dec 5. Epub 2018 Dec 5.

Division of Cardiology, Department of Medicine II, Kansai Medical University, 2-5-1, Shin-machi, Hirakata, 573-1010, Osaka, Japan.

Diastolic wall strain (DWS) was reported as a simple and feasible echocardiographic index in assessing left ventricular (LV) diastolic stiffness. We sought to evaluate whether DWS predicts age-related cardiovascular events. Patients referred for transthoracic echocardiogram, those with preserved LV ejection fraction and no clinical heart failure were studied. Read More

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http://dx.doi.org/10.1007/s00380-018-1311-5DOI Listing
December 2018
2 Reads

The clinical impact of sex differences on ischemic postconditioning during primary percutaneous coronary intervention: a POST (the effects of postconditioning on myocardial reperfusion in patients with ST-segment elevation myocardial infarction) substudy.

Heart Vessels 2018 Dec 5. Epub 2018 Dec 5.

Kyungpook National University Hospital, Daegu, South Korea.

The POST (the effects of postconditioning on myocardial reperfusion in patients with ST-Segment elevation myocardial infarction) study showed that ischemic postconditioning did not improve myocardial reperfusion in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI). However, it has not been determined whether postconditioning is effective in women. This study sought to evaluate the impact of sex differences on ischemic postconditioning during the primary PCI. Read More

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http://link.springer.com/10.1007/s00380-018-1316-0
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http://dx.doi.org/10.1007/s00380-018-1316-0DOI Listing
December 2018
7 Reads

Assessment of coronary flow reserve predicts long-term outcome of responders to cardiac resynchronization therapy.

Heart Vessels 2018 Nov 27. Epub 2018 Nov 27.

Department of Cardiology and Clinical Examination, Faculty of Medicine, Oita University, 1-1 Idaigaoka, Hasama, Yufu City, Oita, 879-5593, Japan.

Cardiac resynchronization therapy (CRT) has been established as a treatment for patients with chronic heart failure (HF). We tested the hypothesis that assessment of coronary flow reserve (CFR) predicts the long-term outcome of CRT. The study consisted of 114 HF patients implanted with a CRT device for the treatment of advanced HF between April 2010 and April 2018. Read More

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http://dx.doi.org/10.1007/s00380-018-1308-0DOI Listing
November 2018
1 Read

Differential incidence and morphology of provoked spasm between intracoronary acetylcholine and ergonovine testing: recommendation of supplementary use.

Heart Vessels 2018 Nov 24. Epub 2018 Nov 24.

Department of Cardiology, Tsukazaki Hospital, Himeji, Japan.

When cardiologists diagnose patients with coronary spastic angina, Japanese Circulation Society (JCS) guidelines recommend the intracoronary injection of acetylcholine (ACh) and ergonovine (ER) as class I. However, the pharmacological difference between ACh and ER is controversial in the clinic. We performed both ACh and ER tests in the same 528 patients during 26 years. Read More

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http://dx.doi.org/10.1007/s00380-018-1299-xDOI Listing
November 2018
7 Reads

Prevalence of subcutaneous implantable cardioverter-defibrillator based on template ECG screening and ineligible surface ECG predicting factors in patients with hypertrophic cardiomyopathy in China.

Heart Vessels 2018 Nov 21. Epub 2018 Nov 21.

Department of Ultrasound, The First Affiliated Hospital, Fourth Military Medical University, No. 127 Changle West Road, Xi'an, 710032, Shaanxi, China.

The subcutaneous implantable cardioverter-defibrillator (S-ICD) may provide comparable protection while avoiding the disadvantage of transvenous lead, but the abnormal features of the hypertrophic cardiomyopathy (HCM) electrocardiogram (ECG) make it a challenge for S-ICD template screening. We aimed to investigate S-ICD eligibility according to the S-ICD manufacturer's surface ECG screening template in China, and further analyze its corresponding ineligible predicting factors in 12-lead suface ECG. A total of 179 HCM patients (114 males; mean age: 45 ± 14 years) underwent S-ICD screening at rest and on exercise, among which 91 patients (50. Read More

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http://dx.doi.org/10.1007/s00380-018-1300-8DOI Listing
November 2018
19 Reads
2.109 Impact Factor