1,514 results match your criteria Heart Block Second Degree


Frequency and characteristics of exercise-induced second-degree atrioventricular block in patients undergoing stress testing.

J Electrocardiol 2019 Mar 14;54:54-60. Epub 2019 Mar 14.

Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, United States of America.

Background: Spontaneous second-degree atrioventricular block induced by exercise (Ex2AVB) is rare, but it can cause profound exercise intolerance.

Objective: We sought to determine the frequency of Ex2AVB in our exercise testing practice and to describe characteristics of patients with Ex2AVB. We hypothesized that the number of patients would be small, but they would require invasive treatment. Read More

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http://dx.doi.org/10.1016/j.jelectrocard.2019.03.009DOI Listing
March 2019
1 Read

[Abnormal ECG findings in athletes].

Authors:
Pietro Delise

G Ital Cardiol (Rome) 2019 Apr;20(4):242-253

U.O. Cardiologia, Ospedale P. Pederzoli, Peschiera del Garda (VR).

Athlete's heart, as a consequence of exercise training, is characterized by hypervagotonia and enlargement of cardiac chambers. Such modifications influence the electrocardiogram. In fact, athletes frequently present with common cardiac alterations, including sinus bradycardia, first and second degree atrioventricular block, increased QRS voltage, and early repolarization. Read More

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http://www.giornaledicardiologia.it/articoli.php?archivio=ye
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http://dx.doi.org/10.1714/3126.31077DOI Listing
April 2019
6 Reads

Cardiac Arrhythmias in Horses.

Authors:
Gunther van Loon

Vet Clin North Am Equine Pract 2019 Apr 11;35(1):85-102. Epub 2019 Mar 11.

Department of Large Animal Internal Medicine, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, Merelbeke 9820, Belgium. Electronic address:

Arrhythmias are common in horses. Sinus arrhythmia and first- and second-degree atrioventricular block are frequently found physiologic arrhythmias, but should immediately disappear after stress or exercise. Atrial premature depolarizations are usually not associated with poor performance, but are a potential trigger for atrial fibrillation. Read More

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http://dx.doi.org/10.1016/j.cveq.2018.12.004DOI Listing
April 2019
1 Read

Second-degree interatrial block: A case series.

J Electrocardiol 2019 Feb 7;54:18-21. Epub 2019 Feb 7.

Division of Cardiology, Kingston Health Science Center, Queen's University, Kingston, Ontario, Canada.

Advanced interatrial block (IAB) (P-wave ≥120 ms and biphasic P-wave in leads II, III and aVF) is a prevalent ECG pattern frequently associated with supraventricular arrhythmias and stroke, especially in patients with structural heart disease. Intermittent IAB is a much more poorly defined electrocardiographic entity with uncertain clinical significance. In this case series, we review and analyze eight cases of second degree intermittent IAB. Read More

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http://dx.doi.org/10.1016/j.jelectrocard.2019.02.001DOI Listing
February 2019
1 Read

Case report: Atrioventricular block after transcatheter atrial septal closure using the Figulla® Flex II ASD occluder.

Catheter Cardiovasc Interv 2019 Apr 17;93(5):E298-E301. Epub 2019 Feb 17.

Department of Paediatric Cardiology, Japan Community Health Organization Chukyo Hospital, Nagoya, Japan.

We report a 7-year-old male patient who developed severe atrioventricular block after transcatheter closure of the atrial septal defect with an Occlutech Figulla® Flex II ASD occluder (FSO). He had a small aortic rim and the defect measuring 22.3 mm by balloon sizing. Read More

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http://dx.doi.org/10.1002/ccd.28148DOI Listing
April 2019
3 Reads

Second degree heart block following the administration of dexmedetomidine.

J Clin Anesth 2019 08 9;55:103-104. Epub 2019 Jan 9.

Division of Pediatric Critical Care Medicine, Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, Madison, WI 53792, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jclinane.2018.12.052DOI Listing
August 2019
2 Reads

Resolution of fetal second-degree atrioventricular block.

J Electrocardiol 2018 Nov - Dec;51(6):945-947. Epub 2018 Aug 17.

University of Massachusetts Medical School, Department of Pediatric Cardiology, 55 Lake Avenue North, Worcester, MA 01655, United States of America.

Fetal atrioventricular (AV) block is a rare and potentially devastating condition. Most commonly fetal AV block is mediated by maternal lupus antibodies which cause irreversible damage to the AV node. For many fetuses, the only potential intervention is premature delivery and highly invasive pacemaker implantation. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00220736183048
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http://dx.doi.org/10.1016/j.jelectrocard.2018.08.020DOI Listing
August 2018
17 Reads

Dysrhythmias in patients with a complete atrioventricular septal defect: From surgery to early adulthood.

Congenit Heart Dis 2019 Mar 28;14(2):280-287. Epub 2018 Nov 28.

Department of Cardiothoracic Surgery, Erasmus University Medical Center, Rotterdam, The Netherlands.

Objective: Outcomes after surgical repair of complete atrioventricular septal defect (cAVSD) have improved. With advancing age, the risk of development of dysrhythmias may increase. The aims of this study were to (1) examine development of sinus node dysfunction (SND), atrial and ventricular tachyarrhythmias, and (2) study progression of atrioventricular conduction abnormalities in young adult patients with repaired cAVSD. Read More

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http://dx.doi.org/10.1111/chd.12724DOI Listing
March 2019
6 Reads

Safety of regadenoson positon emission tomography stress testing in orthotopic heart transplant patients.

J Nucl Cardiol 2018 Nov 27. Epub 2018 Nov 27.

University of Michigan Frankel Cardiovascular Center, 1500 East Medical Center Drive, Ann Arbor, MI, 48109-5853, USA.

Objectives: We sought to determine the safety of regadenoson (REG) stress testing in patients who have undergone orthotopic heart transplantation (OHT).

Background: Routine screening for cardiac allograft vasculopathy (CAV) is necessary after OHT. Adenosine stress is contraindicated after heart transplantation due to supersensitivity in denervated hearts. Read More

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http://dx.doi.org/10.1007/s12350-018-01466-1DOI Listing
November 2018
3 Reads

Prenatal heart block screening in mothers with SSA/SSB autoantibodies: Targeted screening protocol is a cost-effective strategy.

Congenit Heart Dis 2019 Mar 16;14(2):221-229. Epub 2018 Nov 16.

Children's Heart Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.

Objective: Maternal anti-Ro/SSA and anti-La/SSB antibodies can lead to fetal complete heart block (CHB). Current guidelines recommend weekly echocardiographic screening between 16 and 28 weeks gestation. Given the cost of screening and the rarity of conduction abnormalities in fetuses of mothers with low anti-Ro levels (<50 U/mL), we sought to identify a strategy that optimizes resource utilization. Read More

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http://doi.wiley.com/10.1111/chd.12713
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http://dx.doi.org/10.1111/chd.12713DOI Listing
March 2019
14 Reads

Disruption of RHOA-ROCK Signaling Results in Atrioventricular Block and Disturbed Development of the Putative Atrioventricular Node.

Anat Rec (Hoboken) 2019 Jan 9;302(1):83-92. Epub 2018 Nov 9.

Department of Anatomy & Embryology, Leiden University Medical Center, Leiden, The Netherlands.

The RHOA-ROCK signaling pathway is involved in numerous developmental processes, including cell proliferation, differentiation and migration. RHOA is expressed in the atrioventricular node (AVN) and altered expression of RHOA results in atrioventricular (AV) conduction disorders in mice. The current study aims to detect functional AVN disorders after disturbing RHOA-ROCK signaling in chicken embryos. Read More

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http://doi.wiley.com/10.1002/ar.23912
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http://dx.doi.org/10.1002/ar.23912DOI Listing
January 2019
13 Reads

Advanced Heart Block in Children with Lyme Disease.

Pediatr Cardiol 2019 Mar 31;40(3):513-517. Epub 2018 Oct 31.

Department of Pediatrics, Division of Pediatric Cardiology, Columbia University, College of Physicians and Surgeons, 3959 Broadway, 2-North, New York, NY, USA.

Background: The clinical course of children with advanced heart block secondary to Lyme disease has not been well characterized.

Objective: To review the presentation, management, and time to resolution of heart block due to Lyme disease in previously healthy children.

Methods: An IRB approved single-center retrospective study was conducted of all patients < 21 years old with confirmed Lyme disease and advanced second or third degree heart block between 2007 and 2017. Read More

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http://dx.doi.org/10.1007/s00246-018-2003-8DOI Listing
March 2019
5 Reads

Outcome of Cardiac Sarcoidosis Presenting With High-Grade Atrioventricular Block.

Circ Arrhythm Electrophysiol 2018 Aug;11(8):e006145

Heart and Lung Center (H.-K.N., J.L., K.E., R.K., P.S., M.K.).

Background: Symptomatic high-grade atrioventricular block (AVB) is the most common and often the only presenting manifestation (lone AVB) of cardiac sarcoidosis. Implantation of an intracardiac cardioverter defibrillator instead of a pacemaker is recommended, but the true risk of fatal arrhythmia, one incident to lone AVB in particular, remains poorly known.

Methods: We used Myocardial Inflammatory Diseases in Finland Study Group Registry to analyze the presentations, left ventricular (LV) function, pacemaker therapy, and ventricular arrhythmias in cardiac sarcoidosis. Read More

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https://www.ahajournals.org/doi/10.1161/CIRCEP.117.006145
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http://dx.doi.org/10.1161/CIRCEP.117.006145DOI Listing
August 2018
19 Reads

Left posterior fascicular block, state-of-the-art review: A 2018 update.

Indian Pacing Electrophysiol J 2018 Nov - Dec;18(6):217-230. Epub 2018 Oct 13.

Heart Center, Tampere University Hospital and Faculty of Medicine and Life Sciences, University of Tampere, Finland.

We conducted a review of the literature regarding epidemiology, clinical, electrocardiographic and vectorcardiographic aspects, classification, and differential diagnosis of left posterior fascicular block. Isolated left posterior fascicular block (LPFB) is an extremely rare finding both in the general population and in specific patient groups. In isolated LPFB 20% of the vectorcardiographic (VCG) QRS loop is located in the right inferior quadrant and when associated with right bundle branch block (RBBB) ≥40%. Read More

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http://dx.doi.org/10.1016/j.ipej.2018.10.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302819PMC
October 2018
7 Reads

Home Monitoring for Fetal Heart Rhythm During Anti-Ro Pregnancies.

J Am Coll Cardiol 2018 Oct;72(16):1940-1951

Division of Cardiology, Department of Pediatrics, Hospital for Sick Children, Toronto, Canada.

Background: Fetal atrioventricular block (AVB) occurs in 2% to 4% of anti-Ro antibody-positive pregnancies and can develop in <24 h. Only rarely has standard fetal heart rate surveillance detected AVB in time for effective treatment.

Objectives: Outcome of anti-Ro pregnancies was surveilled with twice-daily home fetal heart rate and rhythm monitoring (FHRM) and surveillance echocardiography. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S07351097183694
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http://dx.doi.org/10.1016/j.jacc.2018.07.076DOI Listing
October 2018
43 Reads

Coma, Seizures, Atrioventricular Block, and Hypoglycemia in an ADB-FUBINACA Body-Packer.

J Emerg Med 2018 Dec 5;55(6):788-791. Epub 2018 Oct 5.

Department of Emergency Medicine, University of Rochester Medical Center, Rochester, New York; Upstate Poison Center, Syracuse, New York.

Background: Synthetic cannabinoid intoxication has become difficult to diagnose and manage in the United States, in part due to varying clinical effects within this heterogeneous group of compounds.

Case Report: A 38-year-old man was admitted with altered mental status and bradycardia. He demonstrated progressive encephalopathy, seizure activity, second-degree atrioventricular block type I, respiratory failure, hypotension, hypothermia, and hypoglycemia. Read More

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http://dx.doi.org/10.1016/j.jemermed.2018.09.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289710PMC
December 2018
13 Reads

A Rare Case of Second Degree Mobitz Type II AV Block Associated with Cocaine Use.

Am J Med Case Rep 2018 21;6(7):146-148. Epub 2018 Aug 21.

Department of Internal Medicine, State University of New York Downstate Medical Center, Brooklyn, New York, U.S.A- 11203.

Cocaine is a commonly abused illicit drug in the United States. The complex effects of cocaine on the conduction system of the human heart has not been completely understood. Cocaine acts as a sympathomimetic by inhibition of reuptake of neuronal catecholamines, leading mostly to tachyarrhythmias on presentation. Read More

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http://pubs.sciepub.com/ajmcr/6/7/7/index.html
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http://dx.doi.org/10.12691/ajmcr-6-7-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173318PMC
August 2018
4 Reads

Potassium levels and risk of in-hospital arrhythmias and mortality in patients admitted with suspected acute coronary syndrome.

Int J Cardiol 2019 Jan 28;274:52-58. Epub 2018 Sep 28.

Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.

Background: In acute coronary syndrome (ACS), potassium imbalance at admission has been associated with in-hospital arrhythmias, cardiac arrest, and mortality. However, several important presentation characteristics and subtype of ACS have not been considered.

Methods: Consecutive patients (n = 32,955) admitted with suspected ACS between 2006 and 2011, registered in the Swedish Web-System for Enhancement and Development of Evidence-Based care in Heart Disease Evaluated According to Recommended Therapies (SWEDEHEART) and the Stockholm CREAtinine Measurements (SCREAM) project were included. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01675273173723
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http://dx.doi.org/10.1016/j.ijcard.2018.09.099DOI Listing
January 2019
11 Reads

Dynamic Electrocardiography is Useful in the Diagnosis of Persistent Atrial Fibrillation Accompanied with Second-Degree Atrioventricular Block.

Acta Cardiol Sin 2018 Sep;34(5):409-416

Department of Cardiology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310003, China.

Background: Periodic electrocardiography (ECG) at every clinical visit is generally performed for heart rhythm surveillance, and 24-h Holter ECG is usually used as the gold standard. We aimed to investigate the electrocardiographic features of persistent atrial fibrillation (AF) accompanied with second-degree atrioventricular block (AVB).

Methods: From October 2012 to November 2015, 204 patients with an RR interval > 2. Read More

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http://dx.doi.org/10.6515/ACS.201809_34(5).20180326EDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160510PMC
September 2018
5 Reads
0.840 Impact Factor

Treating Lyme carditis high-degree AV block using a temporary-permanent pacemaker.

Ann Noninvasive Electrocardiol 2019 May 28;24(3):e12599. Epub 2018 Sep 28.

Division of Cardiology, Kingston Health Science Center, Queen's University, Kingston, Ontario, Canada.

A 28-year-old previously healthy male presented with nonprodromal syncope and a 4-day history of chest pain, shortness of breath, and malaise. His ECG showed rapidly progressive high-degree AV block. His Suspicious Index in Lyme Carditis (SILC) score was 8, indicating high risk for Lyme carditis. Read More

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http://dx.doi.org/10.1111/anec.12599DOI Listing
May 2019
15 Reads

Frequency and Significance of High-Degree Atrioventricular Block and Sinoatrial Node Dysfunction in Patients With Non-ST-Elevation Myocardial Infarction.

Am J Cardiol 2018 Nov 21;122(10):1598-1603. Epub 2018 Aug 21.

Division of Cardiovascular Medicine, Gill Heart Institute, University of Kentucky, Lexington, KY and VA Medical Center, Lexington, Kentucky.

Characteristics of conduction disorders after ST-elevation myocardial infarction (STEMI) have been well described. In contrast, limited data are available on the incidence, treatment trends, and prognostic impact of conduction disorders after non-ST-elevation myocardial infarction (NSTEMI). Using the National Inpatient Sample database, we compared the characteristics and outcomes of conduction disorders in patients with a primary diagnosis of STEMI versus NSTEMI between 2010 and 2014. Read More

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http://dx.doi.org/10.1016/j.amjcard.2018.08.001DOI Listing
November 2018
7 Reads

Rapid Progression of Heart Failure in a Patient with Idiopathic Inflammatory Myopathy.

Am J Med Case Rep 2018 23;6(8):157-160. Epub 2018 Aug 23.

Divisions of Cardiovascular Disease and Rheumatology, Department of Internal Medicine, State University of New York, Downstate Medical Center, Brooklyn, New York, U.S.A- 11203.

Idiopathic inflammatory myopathy (IIM) is a rare autoimmune myopathy that includes polymyositis, dermatomyositis, inclusion body myositis and autoimmune necrotizing myositis. Cardiac involvement was considered a rare occurrence in IIM however, recent reports suggests that cardiac involvement is a common feature and portends poor prognosis as it is usually encountered in advanced disease. IIM leads to myocarditis with subsequent development of myocardial fibrosis, cardiac conduction system disease and cardiomyopathy resulting in both systolic and diastolic heart failure. Read More

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http://dx.doi.org/10.12691/ajmcr-6-8-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138443PMC
August 2018
19 Reads

A new and simple technique for vagal ganglia ablation in a patient with functional atrioventricular block: Electroanatomical approach.

Turk Kardiyol Dern Ars 2018 09;46(6):494-500

Department of Cardiology, University of Health Sciences, Kocaeli Derince Training and Research Hospital, Kocaeli, Turkey.

Increased parasympathetic tone may cause symptomatic functional atrioventricular block (AVB) and necessitate pacemaker implantation. In these patients, where there is no structural damage to the conduction system, removal of the vagal activity using radiofrequency ablation seems to be a theoretically rational approach. Several methods have been used to determine suitable areas for vagal ganglia ablation. Read More

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http://dx.doi.org/10.5543/tkda.2017.15163DOI Listing
September 2018
3 Reads

Association between decreasing estimated glomerular filtration rate and risk of cardiac conduction defects in patients with type 2 diabetes.

Diabetes Metab 2018 12 5;44(6):473-481. Epub 2018 Sep 5.

Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, University and Azienda Ospedaliera Universitaria Integrata of Verona, Piazzale Stefani, 1, 37126 Verona, Italy. Electronic address:

Aim: We aimed to assess the association between decreasing estimated glomerular filtration rate (eGFR) or abnormal albuminuria and the risk of certain cardiac conduction defects in patients with type 2 diabetes mellitus (T2DM).

Methods: We examined a hospital-based sample of 923 patients with T2DM discharged from our Division of Endocrinology over the years 2007-2014. Standard electrocardiograms (ECGs) were performed in all patients. Read More

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http://dx.doi.org/10.1016/j.diabet.2018.08.007DOI Listing
December 2018
4 Reads

Second-degree interatrial block: Brief review and concept.

Ann Noninvasive Electrocardiol 2018 Nov 2;23(6):e12583. Epub 2018 Sep 2.

National Academy of Medicine, Buenos Aires, Argentina.

The advanced interatrial block (A-IAB) (P ≥ 120 ms plus ± pattern in II, III and aVF) corresponds at atrial level, to right or left advanced bundle branch block at ventricular level, and it is well known that these patterns may be seen transiently in relation to taquicardia or bradycardia (tachycardia or bradycardia dependent right or left bundle branch block). We present for the first time, the same phenomenon at atrial level. In one case, the A-IAB appears in relation to tachycardization and in the other disappears during a pause induced by ventricular premature complex. Read More

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http://dx.doi.org/10.1111/anec.12583DOI Listing
November 2018
5 Reads

Cardiac Resynchronisation Therapy (CRT) Survey II: CRT implantation in Europe and in Switzerland.

Swiss Med Wkly 2018 Aug 22;148:w14643. Epub 2018 Aug 22.

University Hospital Basel, Switzerland.

Aim: Between October 2015 and December 2016, 11,088 patients from 42 countries having cardiac resynchronisation therapy (CRT) devices implanted were included in the CRT II Survey. We compared the characteristics of Swiss CRT recipients with the overall European population.

Methods: Demographic and procedural data from seven Swiss centres recruiting all consecutive patients undergoing either de-novo CRT implantation or an upgrade to a CRT system were collected and compared with the European population. Read More

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http://dx.doi.org/10.4414/smw.2018.14643DOI Listing
August 2018
8 Reads

The prevention, screening and treatment of congenital heart block from neonatal lupus: a survey of provider practices.

Rheumatology (Oxford) 2018 07;57(suppl_5):v9-v17

Division of Rheumatology, New York University School of Medicine, NY, USA.

Objective: To survey an international sample of providers to determine their current practices for the prevention, screening, and treatment of congenital heart block (CHB) due to maternal Ro/SSA antibodies.

Methods: A survey was designed by the organizing committee of the 9th International Conference of Reproduction, Pregnancy and Rheumatic Diseases. It was sent to attendants of the conference and authors of recent publications or abstracts at ACR 2012, 2013 or 2014 on rheumatic diseases and pregnancy. Read More

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http://dx.doi.org/10.1093/rheumatology/key141DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099126PMC
July 2018
33 Reads

Type I Second Degree Atrioventricular Block in a Woman With Remote Repair of a Ventricular Septal Defect.

Am J Cardiol 2018 Sep 23;122(6):1111-1112. Epub 2018 Jun 23.

Section of Cardiology, Department of Medicine, Louisiana State University Health Sciences Center, New Orleans, Louisiana. Electronic address:

In a 45-year-old woman with syncope, an electrocardiogram revealed intermittent asymptomatic type I second degree atrioventricular block, right bundle branch block and left anterior fascicular block. An echocardiogram documented concentric left ventricular hypertrophy and right ventricular dilatation and hypokinesia. Because the patient did not have second degree atrioventricular block at the time of an electrophysiological study, the atrioventricular node, the left posterior fascicle, and the His bundle all remain potential sites for the type I second degree atrioventricular block on her initial electrocardiogram. Read More

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http://dx.doi.org/10.1016/j.amjcard.2018.05.041DOI Listing
September 2018
3 Reads
3.280 Impact Factor

Lyme Carditis: A Case Report and Review of Management.

Hosp Pharm 2018 Jul 2;53(4):263-265. Epub 2018 Jan 2.

University of Pittsburgh Medical Center Mercy, PA, USA.

A case report of a patient who presented with an acute onset, fluctuating atrioventricular (AV) block and was diagnosed with Lyme carditis is presented. A 55-year-old man with progressively worsening generalized malaise, flu-like symptoms, dyspnea on exertion, and near syncope was admitted with bradycardia (heart rate was between 20 and 30 beats per minute upon admission). He endorsed having several tick bites after which he developed erythema migrans on his arm and abdomen. Read More

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http://dx.doi.org/10.1177/0018578717749927DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050884PMC
July 2018
12 Reads

Congenital second-degree heart block and total anomalous pulmonary venous return associated with microduplication of 1q32.2.

Ann Pediatr Cardiol 2018 May-Aug;11(2):194-196

Department of Pediatrics, Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA.

We report a term female infant with congenital heart block and total anomalous of pulmonary venous return. The results of single nucleotide polymorphism oligonucleotide microarray analysis showed an interstitial duplication of approximately 818 Kb, which involved 11 genes, including the entire LAMB3 gene which is known to associate with cardiac conduction defect. Our report adds to the collective knowledge that the cardiac conduction defect is a clinical feature of chromosome 1q32. Read More

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http://dx.doi.org/10.4103/apc.APC_21_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963235PMC
June 2018
3 Reads

Low-energy ablation of anteroseptal accessory pathways in two dogs.

J Vet Cardiol 2018 Aug 30;20(4):285-293. Epub 2018 May 30.

Department of Clinical Sciences, Cornell University, Ithaca, NY 14853, USA.

In humans, accessory pathways (APs) in an anteroseptal and midseptal position are often challenging to ablate because of their close proximity with the conduction pathways of the atrioventricular junction. The use of low-energy ablation techniques can be useful to reduce the risk of permanently damaging the atrioventricular node and the His bundle. This report describes the use of low-energy radiofrequency catheter ablation to successfully and permanently ablate anteroseptal APs in two dogs with orthodromic atrioventricular reciprocating tachycardia. Read More

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http://dx.doi.org/10.1016/j.jvc.2018.05.001DOI Listing
August 2018
3 Reads

The ACURATE neo Transcatheter Heart Valve: A Comprehensive Analysis of Predictors of Procedural Outcome.

JACC Cardiovasc Interv 2018 Sep 23;11(17):1721-1729. Epub 2018 May 23.

Department of Cardiac Surgery, Johann-Wolfgang-Goethe University, Frankfurt, Germany.

Objectives: The aim of this study was to perform a comprehensive analysis of factors that affect procedural outcomes of transcatheter aortic valve replacement using the ACURATE neo prosthesis (Symetis/Boston, Ecublens, Switzerland).

Background: Predictors of procedural outcomes using the ACURATE neo prosthesis are poorly understood.

Methods: A total of 500 patients underwent transfemoral aortic valve replacement with the ACURATE neo prosthesis. Read More

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http://dx.doi.org/10.1016/j.jcin.2018.04.039DOI Listing
September 2018
14 Reads

Glibenclamide Prevents Hypoglycemia-Induced Fatal Cardiac Arrhythmias in Rats.

Endocrinology 2018 07;159(7):2614-2620

Division of Endocrinology, Metabolism, and Diabetes, Department of Internal Medicine, University of Utah, Salt Lake City, Utah.

Sulfonylureas increase the incidence of severe hypoglycemia in people with type 2 diabetes and might increase the risk of sudden cardiac death. Sulfonylureas stimulate insulin secretion by closing pancreatic ATP-sensitive potassium ion (KATP) channels. To investigate the role of KATP channel modulators on cardiac arrhythmias and mortality in the setting of severe hypoglycemia, adult Sprague-Dawley rats underwent hyperinsulinemic (0. Read More

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http://dx.doi.org/10.1210/en.2018-00419DOI Listing
July 2018
6 Reads

Safety, tolerability, pharmacokinetics, and pharmacodynamics of GLPG1690, a novel autotaxin inhibitor, to treat idiopathic pulmonary fibrosis (FLORA): a phase 2a randomised placebo-controlled trial.

Lancet Respir Med 2018 08 20;6(8):627-635. Epub 2018 May 20.

Unit for Interstitial Lung Diseases, Department of Pulmonary Medicine, University Hospitals Leuven, Leuven, Belgium.

Background: Idiopathic pulmonary fibrosis (IPF) causes irreversible loss of lung function. People with IPF have increased concentrations of autotaxin in lung tissue and lysophosphatidic acid (LPA) in bronchoalveolar lavage fluid and exhaled condensate. GLPG1690 (Galapagos, Mechelen, Belgium) is a novel, potent, selective autotaxin inhibitor with good oral exposure. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S22132600183018
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http://dx.doi.org/10.1016/S2213-2600(18)30181-4DOI Listing
August 2018
43 Reads

A case of narrow complex bigeminy, what is the underlying rhythm?

J Electrocardiol 2018 May - Jun;51(3):379-381. Epub 2018 Mar 16.

Department of Internal Medicine, University of California San Francisco, 505 Parnassus Avenue., Rm. 987, San Francisco, CA 94143, USA; Division of Cardiology, Department of Internal Medicine, Zuckerberg San Francisco General Hospital, 1001 Potrero Ave, San Francisco, CA 94110, USA. Electronic address:

Narrow complex bigeminy is a common electrocardraphic finding that can be caused by second degree sinoatrial exit block or ectopic atrial bigeminy. These rhythms can be very challenging to distinguish on a 12-lead electrocardiogram. In this case of an elderly woman who presented with narrow complex bigeminy, we review the differentiating features of second degree sinoatrial exit block and ectopic atrial bigeminy. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00220736183004
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http://dx.doi.org/10.1016/j.jelectrocard.2018.03.005DOI Listing
March 2019
4 Reads

Primary central sleep apnea and anesthesia: a retrospective case series.

Can J Anaesth 2018 Aug 1;65(8):884-892. Epub 2018 May 1.

Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, 200 First St SW, Rochester, MN, 55905, USA.

Purpose: Primary (idiopathic) central sleep apnea (PCSA) is a rare central sleep-related breathing disorder characterized by increased chemoreceptor sensitivity to partial pressure of carbon dioxide, which manifests as hyperventilation followed by apnea during non-rapid eye movement sleep. The purpose of this retrospective study was to describe the postoperative course of patients who had PCSA and underwent procedures requiring anesthetic management.

Methods: Patients who received a diagnosis of PCSA at our institution and required procedural anesthesia between 1 January 2010 and 1 June 2016 underwent a comprehensive review of their health records with a focus on identifying respiratory complications. Read More

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http://dx.doi.org/10.1007/s12630-018-1144-9DOI Listing
August 2018
8 Reads

Acute Pediatric Colchicine Toxicity is Associated with Marked Bradydysrhythmias.

J Emerg Med 2018 09 29;55(3):e65-e69. Epub 2018 May 29.

Division of Cardiology, Department of Pediatrics, Rush University Medical College, Chicago, Illinois.

Background: Colchicine ingestion is rare but highly lethal. Patients usually die of multiorgan failure and cardiogenic shock. Colchicine is not only associated with depressed myocardial function but also with fatal heart rhythm disturbances, such as complete heart block, ventricular tachycardia, and asystole. Read More

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http://dx.doi.org/10.1016/j.jemermed.2018.03.004DOI Listing
September 2018
6 Reads

Clinical and electrocardiographic presentations of transient trifascicular block in three cats.

J Vet Cardiol 2018 Jun 20;20(3):204-212. Epub 2018 Mar 20.

Cornell University College of Veterinary Medicine, 930 Campus Road, 14853, Ithaca, NY, USA. Electronic address:

This report describes transient trifascicular block in three cats presented with lethargy and inappetence, and elevated cardiac troponin I concentrations. The electrocardiogram (ECG) of cat 1 showed a sinus rhythm with pronounced first-degree atrioventricular (AV) block, right bundle branch block, and left anterior fascicular block. The ECG of cat 2 showed truncular left bundle branch block alternating with left anterior fascicular block coupled with prolonged PR intervals, second-degree heart block, and paroxysmal third-degree AV block. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S17602734173020
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http://dx.doi.org/10.1016/j.jvc.2018.02.002DOI Listing
June 2018
14 Reads

Beer, hyponatraemia and cardiac conduction defects.

BMJ Case Rep 2018 Mar 14;2018. Epub 2018 Mar 14.

Department of Medicine, Mater Dei Hospital, Msida, Malta.

The authors report a case of a 68-year-old man who was diagnosed with an irreversible second-degree atrioventricular (AV) Mobitz II 2:1 block temporally associated with profound hyponatraemia. The cause of the hyponatraemia was beer potomania. The co-occurrence of reversible first, second and third-degree heart blocks and hyponatraemia has been described in a few published case reports. Read More

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http://dx.doi.org/10.1136/bcr-2018-224260DOI Listing
March 2018
22 Reads

Maternal steroid therapy for fetuses with second-degree immune-mediated congenital atrioventricular block: a systematic review and meta-analysis.

Acta Obstet Gynecol Scand 2018 Jul 18;97(7):787-794. Epub 2018 Apr 18.

Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Sidney Kimmel Medical College of Thomas Jefferson University, Philadelphia, PA, USA.

Introduction: The aim of this study was to explore the effect of maternal fluorinated steroid therapy on fetuses affected by second-degree immune-mediated congenital atrioventricular block.

Material And Methods: Studies reporting the outcome of fetuses with second-degree immune-mediated congenital atrioventricular block diagnosed on prenatal ultrasound and treated with fluorinated steroids compared with those not treated were included. The primary outcome was the overall progression of congenital atrioventricular block to either continuous or intermittent third-degree congenital atrioventricular block at birth. Read More

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http://dx.doi.org/10.1111/aogs.13338DOI Listing
July 2018
30 Reads
1.990 Impact Factor

Case presentation: implantation of cardiac resynchronization therapy pacemaker via the coronary sinus in a patient with triple valve replacement.

BMC Cardiovasc Disord 2018 02 21;18(1):37. Epub 2018 Feb 21.

Department of Cardiology, Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, 109 Xueyuan Road, Wenzhou, Zhejiang, 325000, China.

Background: In patients with triple valve replacement developing third-degree atrioventricular block (AVB), the most appropriate approach for permanent pacemaker implantation remains questionable.

Case Presentation: In this case presentation, we first described the approach of implantation of the cardiac resynchronization therapy pacemaker (CRT-P) via one bipolar pacing lead in middle cardiac vein (MCV) and one quadripolar pacing lead in anterior interventricular vein (AIV) in a patient developing complete AVB, who had been previously diagnosed with rheumatic valvular heart disease with triple valve replaced. After the CRT-P implantation, the two pacing leads in coronary sinus (CS) provided a dual-site ventricular pacing from the anterior septum and posterior septum, which resulted in a narrow QRS complex and an increased ventricular synchrony. Read More

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https://bmccardiovascdisord.biomedcentral.com/articles/10.11
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http://dx.doi.org/10.1186/s12872-018-0775-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5822565PMC
February 2018
21 Reads

Type I Wenckebach second-degree AV block: A matter of definition.

Authors:
S Serge Barold

Clin Cardiol 2018 03 20;41(3):282-284. Epub 2018 Feb 20.

Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York.

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http://dx.doi.org/10.1002/clc.22874DOI Listing
March 2018
1 Read

A case of cardiac sarcoidosis mimicking cardiac amyloidosis on cardiovascular magnetic resonance.

ESC Heart Fail 2018 04 5;5(2):306-310. Epub 2018 Feb 5.

Department of Cardiology and Nuclear Medicine, National Center for Global Health and Medicine, Tokyo, Japan.

A 52-year-old male visited our hospital with abnormal electrocardiogram and exertional fatigue. The electrocardiogram showed first-degree atrioventricular block, complete right bundle branch block, and inverted T waves in Leads II, III, aVF, V3, and V4. Echocardiography showed biventricular wall thickening involving granular sparkling of the interventricular septum. Read More

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http://doi.wiley.com/10.1002/ehf2.12263
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http://dx.doi.org/10.1002/ehf2.12263DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880662PMC
April 2018
19 Reads

The analysis of the parameters of 24-hr ECG Holter monitoring in patients with blood neoplasms undergoing high-dose chemotherapy and stem cell transplantation.

Ann Noninvasive Electrocardiol 2018 07 24;23(4):e12534. Epub 2018 Jan 24.

Department of Internal Medicine, Occupational Diseases and Hypertension, Wroclaw Medical University, Wroclaw, Poland.

Background: Hematopoietic stem cell transplantation (HSCT) is a widely used procedure in the treatment of malignant diseases, including blood neoplasms and has increased survival in hematological diseases. The aim of the study was to analyze parameters of 24-hr ECG monitoring in patients with selected blood neoplasms in whom the procedure of hematopoietic stem cell transplantation was performed.

Methods: The study group consisted of 64 adults diagnosed with hematologic cancer qualified for HSCT with the previous high dose chemotherapy (HDC). Read More

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http://doi.wiley.com/10.1111/anec.12534
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http://dx.doi.org/10.1111/anec.12534DOI Listing
July 2018
13 Reads

Efficacy and Safety of Subcutaneous Neostigmine for Ileus, Acute Colonic Pseudo-obstruction, or Refractory Constipation.

Ann Pharmacother 2018 Jun 23;52(6):505-512. Epub 2018 Jan 23.

1 Duke University Hospital, Durham, NC, USA.

Background: Neostigmine is traditionally administered intravenously for treatment of acute colonic pseudo-obstruction (ACPO), though use is associated with administration constraints and adverse effects.

Objective: To evaluate whether an alternative route of administration for neostigmine via subcutaneous (SQ) delivery is safe and effective in a broad cohort of medical and surgical patients.

Methods: This multicenter, retrospective observational study included adult patients administered SQ neostigmine for ileus, ACPO, or refractory constipation. Read More

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http://dx.doi.org/10.1177/1060028018754302DOI Listing
June 2018
10 Reads

Experience of Asian males communicating cardiac genetic risk within the family.

J Community Genet 2018 Jul 8;9(3):293-303. Epub 2018 Jan 8.

Cardiovascular Research Institute, National University Health System, 1E Kent Ridge Road, NUHS Tower Block, Level 9, Singapore, Singapore.

The genetic nature of an inherited cardiac condition (ICC) places first- and second-degree relatives at risk of cardiac complications and sudden death, even in the absence of symptoms. Communication of cardiac genetic risk information allows at-risk relatives to clarify, manage, and potentially prevent ICC-associated risks through cardiac screening. Literature regarding family communication of genetic risk information are predominantly based on Western populations, with limited insight into the Asian experience. Read More

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http://dx.doi.org/10.1007/s12687-017-0352-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002304PMC
July 2018
4 Reads

Cardiovascular magnetic resonance imaging and clinical performance of somatostatin receptor positron emission tomography in cardiac sarcoidosis.

ESC Heart Fail 2018 04 12;5(2):249-261. Epub 2017 Dec 12.

Department of Internal Medicine II, Cardiology, Pneumology and Angiology, University Hospital Bonn, Bonn, Germany.

Aims: Cardiac affection constitutes a major limiting condition in systemic sarcoidosis. The primary objective of this study was to investigate the persistence rate of cardiac sarcoid involvement by cardiovascular magnetic resonance (CMR) imaging in patients diagnosed with cardiac sarcoidosis (CS). Moreover, we examined the additional insights into myocardial damage's characteristics gained by somatostatin receptor scintigraphy. Read More

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http://dx.doi.org/10.1002/ehf2.12243DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880659PMC
April 2018
13 Reads

Cardiac involvement in myotonic dystrophy: The role of troponins and N-terminal pro B-type natriuretic peptide.

Atherosclerosis 2017 Dec 21;267:110-115. Epub 2017 Oct 21.

Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Via Massarenti 9, 40138 Bologna, Italy. Electronic address:

Background And Aims: Myotonic dystrophy type 1 (DM1) and type 2 (DM2) are dominant inherited muscular dystrophies with multiple systemic involvement, often producing cardiac injury. This study sought to determine the clinical significance of elevated high sensitivity cardiac troponin T and I (hs-cTnT and hs-cTnI), and N-terminal pro B-type natriuretic peptide (NT-pro-BNP) in this population.

Methods: Sixty DM patients (35 men and 25 women; mean age: 45. Read More

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http://dx.doi.org/10.1016/j.atherosclerosis.2017.10.020DOI Listing
December 2017
18 Reads