1,559 results match your criteria Heart Block Second Degree


Lamin A/C Cardiomyopathy with E203K Pathogenic Mutation.

Cureus 2020 Apr 21;12(4):e7761. Epub 2020 Apr 21.

Pediatrics, Beaumont Hospital, Royal Oak, USA.

Lamin A/C (LMNA) cardiomyopathy is an adult-onset, autosomal dominant, rapidly progressive cardiomyopathy which belongs to a spectrum of familial idiopathic cardiomyopathies. It is the most common type of familial dilated cardiomyopathy that is associated with conduction defects. A 76-year-old African American female with second-degree atrioventricular (AV) block presented for evaluation of persistent fatigue. Read More

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http://dx.doi.org/10.7759/cureus.7761DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243065PMC

Gender Differences in Rates of Arrhythmias, Cardiac Implantable Electronic Devices, and Diagnostic Modalities Among Sarcoidosis Patients.

Cureus 2020 Apr 14;12(4):e7667. Epub 2020 Apr 14.

Radiology, Hospital of the University of Pennsylvania, Philadelphia, USA.

Introduction Sarcoidosis is a granulomatous disease with multiorgan involvement. Cardiac involvement may be asymptomatic or present clinically as heart failure, arrhythmias, or even sudden cardiac death. In this study, we compared gender differences in the prevalence of arrhythmias and associated outcomes in patients with sarcoidosis without established coronary artery disease. Read More

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http://dx.doi.org/10.7759/cureus.7667DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226665PMC

Very late-onset endocarditis complicated by non-significant aortic regurgitation after device closure of perimembranous ventricular septal defect.

Medicine (Baltimore) 2020 May;99(19):e20120

Department of Pediatric Cardiology.

Introduction: Aortic regurgitation (AR) was recognized as a major, but rare complication after device closure for perimembranous ventricular septal defects (PmVSD). Most of them are temporary and non-significant. Infectious endocarditis (IE) is another extremely rare post-procedure complication of PmVSD. Read More

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http://dx.doi.org/10.1097/MD.0000000000020120DOI Listing

Nontransient third-degree heart block and persistent respiratory findings as sequelae of acute occupational exposure to pyrethroids insecticide.

Am J Ind Med 2020 Jul 16;63(7):644-648. Epub 2020 Apr 16.

Occupational & Environmental Medicine of Long Island, Northwell Health and Occupational Medicine, New York, New York.

We present the case of a worker with occupational exposure to a pyrethroid insecticide who acutely developed nontransient third-degree heart block. In 2000, a 57-year-old male truck driver on his delivery route was accidentally exposed to pyrethroid insecticide being sprayed for West Nile virus containment. Both the driver and his vehicle were coated with the spray. Read More

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http://dx.doi.org/10.1002/ajim.23111DOI Listing

Validation of scoring system predicting permanent pacemaker implantation after transcatheter aortic valve replacement.

Pacing Clin Electrophysiol 2020 May 2;43(5):479-485. Epub 2020 May 2.

University of Texas McGovern Medical School, Houston, Texas.

Background: Transcatheter aortic valve replacement (TAVR) is being increasingly performed in patients with severe aortic stenosis. Despite newer generation valves, atrioventricular (AV) conduction disturbance is a common complication, necessitating permanent pacemaker (PPM) implantation in about 10% of patients. Hence, it is imperative to improve periprocedural risk stratification to predict PPM implantation after TAVR. Read More

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http://dx.doi.org/10.1111/pace.13910DOI Listing

Effect of primary PCI on the recovery of atrioventricular block in inferior STEMI patients with late presentation (>12 hours): insights from a single center 10-year experience.

J Investig Med 2020 Mar 25. Epub 2020 Mar 25.

Department of Cardiovascular Medicine, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China

There is no definite reperfusion time for inferior ST-elevation myocardial infarction (STEMI) patients presenting later than 12 hours after symptom onset and complicated by newly-developed atrioventricular block (AVB). It is not clear whether the percutaneous coronary intervention (PCI) could facilitate the recovery of AVB in this patient group. We conducted a retrospective study including 52 consecutive inferior STEMI patients with presenting time >12 hours and new onset second or third-degree AVB on admission. Read More

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http://dx.doi.org/10.1136/jim-2019-001255DOI Listing

Cardiac effects of repeated focal seizures in rats induced by intrahippocampal tetanus toxin: Bradyarrhythmias, tachycardias, and prolonged interictal QT interval.

Epilepsia 2020 Apr 22;61(4):798-809. Epub 2020 Mar 22.

School of Biomedical Engineering, Purdue University, West Lafayette, Indiana.

Objective: To determine electrical changes in the heart in a chronic, nonstatus model of epilepsy.

Methods: Electrocorticography (ECoG) and electrocardiography (ECG) of nine animals (five made epileptic by intrahippocampal injection of tetanus neurotoxin (TeNT) and four controls), are monitored continuously by radiotelemetry for up to 7 weeks.

Results: Epileptic animals develop a median of 168 seizures, with postictal tachycardias reaching a mean of 487 beats/min and lasting a mean of 661 seconds. Read More

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http://dx.doi.org/10.1111/epi.16479DOI Listing

The need for permanent pacemaker after restoration of conduction following atrioventricular block: a retrospective cohort study.

Turk Kardiyol Dern Ars 2020 Mar;48(2):103-108

Department of Cardiology, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran.

Objective: A permanent pacemaker (PPM) is necessary for patients with a symptomatic third-degree or advanced second-degree atrioventricular (AV) block. An AV block due to medication use can often be reversed; however, subsequent relapse can occur and necessitate subsequent PPM implantation. The aim of this study was to explore the course and prognosis of patients with an AV block. Read More

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http://dx.doi.org/10.5543/tkda.2019.96613DOI Listing

[Increased Ventricular Pacing Threshold Caused by Intake of Dronedaron].

Dtsch Med Wochenschr 2020 Feb 18;145(4):249-251. Epub 2020 Feb 18.

Südstadtklinikum Rostock, Klinik für Innere Medizin I, Abteilung für Kardiologie.

History:  The 75 year old patient was hospitalized because of vertigo, exertional dyspnea and clamminess. Based on ischemic heart disease with sick sinus syndrome a pacemaker was implanted 5.5 years ago. Read More

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http://dx.doi.org/10.1055/a-1025-2610DOI Listing
February 2020

Pembrolizumab-Induced Mobitz Type 2 Second-Degree Atrioventricular Block.

Case Rep Cardiol 2020 28;2020:8428210. Epub 2020 Jan 28.

Department of Cardiology, SUNY Upstate Medical University, USA.

Pembrolizumab is a monoclonal antibody directed towards programmed cell death protein 1 (PD-1) and is an antineoplastic drug which has a growing variety of oncologic uses. Pembrolizumab is commonly associated with immune-related adverse events (IRAEs) but is infrequently noted to cause cardiotoxicities such as myocarditis, arrhythmias, and heart failure. The following case report illustrates the clinical course of a 67-year-old female patient with stage IV non-small-cell lung cancer who developed Mobitz type 2 second-degree atrioventricular block three weeks after receiving her first infusion of pembrolizumab. Read More

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http://dx.doi.org/10.1155/2020/8428210DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7007942PMC
January 2020

Heart Block Caused by Cardiac Metastasis From Merkel Cell Carcinoma: A Case Report.

Mayo Clin Proc Innov Qual Outcomes 2019 Dec 22;3(4):510-516. Epub 2019 Nov 22.

Department of Oncology, Mayo Clinic, Rochester, MN.

Merkel cell carcinoma (MCC) is a rare, rapidly proliferating skin cancer that commonly metastasizes to regional lymph nodes. We present the case of a 73-year-old woman with a history of MCC and non-Hodgkin B-cell lymphoma who presented with second-degree heart block (Mobitz type II) caused by an interatrial mass. Temporary pacing was required before biopsy, which revealed metastatic MCC. Read More

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http://dx.doi.org/10.1016/j.mayocpiqo.2019.09.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978596PMC
December 2019

Survival of a dog with accidental colchicine overdose.

J Vet Emerg Crit Care (San Antonio) 2020 Jan 28;30(1):74-80. Epub 2019 Dec 28.

Department of Medicine, Veterinary Specialist Services, Underwood, Queensland, Australia.

Objective: To describe the treatment and clinical course of a dog accidentally prescribed 10 times the recommended dose of colchicine (0.3 mg/kg/d instead of 0.03 mg/kg/d). Read More

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http://dx.doi.org/10.1111/vec.12919DOI Listing
January 2020

[Exploration of Mahuang Fuzi Xixin Decoction formula syndromes based on severe cases of critical care and its application for nosocomial infection in critical care medicine including hyperpyrexia after tracheotomy and severe pain accompanied by acute myocardial infarction and diabetic peripheral neuropathy].

Authors:
Xing-Jiang Xiong

Zhongguo Zhong Yao Za Zhi 2019 Sep;44(18):3869-3875

Guang'anmen Hospital,China Academy of Chinese Medical Sciences Beijing 100053,China.

Mahuang Fuzi Xixin Decoction recorded in Treatise on Febrile Diseases by Zhang Zhongjing in the Han Dynasty have been widely used in treating Yang deficiency and exogenous wind-cold syndrome by traditional Chinese medicine physicians for thousands of years. The indications of Mahuang Fuzi Xixin Decoction include bradyarrhythmia,sinus bradycardia,sick sinus node syndrome,senile exogenous,asthmatic cold,rhinitis,bronchial asthma,optic neuritis,optic atrophy,sudden blindness,sudden onset of cough,laryngeal obstruction,migraine,joint pain,low back pain,insomnia,shock,heart failure,renal failure,accompanied by fever or nosocomial infection,and hyperpyrexia after tracheotomy; dark complexion,chills,cold limbs,listlessness,fatigue,insomnia,lack of thirst,liking hot drinks,slightly swollen limbs or whole body,pale fat tongue,greasy fur,and deep pulse. Mahuang Fuzi Xixin Decoction is a potential drug for Shaoyin disease complicated with fever and pain. Read More

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http://dx.doi.org/10.19540/j.cnki.cjcmm.20190416.503DOI Listing
September 2019

Pulmonary vein isolation and beyond: Predictive value of vagal reactions in second-generation cryoballoon ablation for the outcome of persistent atrial fibrillation.

Heart Rhythm 2020 Apr 11;17(4):600-606. Epub 2019 Dec 11.

Clinic for Electrophysiology, Herz- und Diabeteszentrum NRW, Ruhr-Universität Bochum, Bad Oeynhausen, Germany.

Background: Cryoballoon ablation (CBA) is gaining increasing acceptance in the treatment of persistent (per) atrial fibrillation (AF). The cardiac autonomic nervous system plays a pivotal role in the regulation of AF.

Objective: We evaluated the impact of vagal reactions (VRs), as a surrogate marker for autonomic nervous system modulation, on the outcome of CBA in patients (pts) with perAF. Read More

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http://dx.doi.org/10.1016/j.hrthm.2019.12.006DOI Listing

Arrhythmia and/or Cardiomyopathy Related to Maternal Autoantibodies: Descriptive Analysis of a Series of 16 Cases From a Single Center.

Front Pediatr 2019 20;7:465. Epub 2019 Nov 20.

School of Medicine, Shandong University, Jinan, China.

To describe the clinical characteristics of maternal autoantibody-mediated arrhythmia and/or cardiomyopathy, and to explore the therapeutic role of glucocorticoids in these diseases. This was a retrospective observational study of 2 fetuses and 14 children who presented with autoantibody-mediated arrhythmia and/or cardiomyopathy in our hospital from September 2010 to December 2018. In total, 16 patients were identified, including 2 fetuses, and 14 children. Read More

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http://dx.doi.org/10.3389/fped.2019.00465DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879546PMC
November 2019

Analysis of cardiac monitoring and safety data in patients initiating fingolimod treatment in the home or in clinic.

BMC Neurol 2019 Nov 15;19(1):287. Epub 2019 Nov 15.

State of the Heart Cardiology, Plaza 1, Medical Pkwy. N Suite 103, Dallas, TX, 75234, USA.

Background: Fingolimod (Gilenya®) is approved for relapsing forms of multiple sclerosis in the USA. Owing to transient heart-rate effects when initiating fingolimod, eligible patients undergo precautionary baseline assessment and first-dose observation (FDO) for ≥6 h. Prior to 2014, FDO was undertaken only in clinics. Read More

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http://dx.doi.org/10.1186/s12883-019-1506-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857316PMC
November 2019
2.040 Impact Factor

Lyme Carditis: A Rare Presentation of Sinus Bradycardia Without Any Conduction Defects.

Cureus 2019 Sep 2;11(9):e5554. Epub 2019 Sep 2.

Family Medicine, Hackensack Meridian Health, Ocean Medical Center, Brick, USA.

Lyme carditis is a rare cardiac manifestation of Lyme disease that occurs when bacterial spirochetes infect the pericardium or myocardium triggering an inflammatory response. The most common electrocardiogram (EKG) findings in these patients include atrioventricular (AV) conduction abnormalities (first, second, and third degree heart block). A 56-year-old male with a history of hypothyroidism, from the Northeastern region of the United States, presented to the emergency department with lightheadedness and chest pain. Read More

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http://dx.doi.org/10.7759/cureus.5554DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820318PMC
September 2019
1 Read

The yield of long-term electrocardiographic recordings in refractory focal epilepsy.

Epilepsia 2019 11 21;60(11):2215-2223. Epub 2019 Oct 21.

Stichting Epilepsie Instellingen Nederland (SEIN), Heemstede, the Netherlands.

Objective: To determine the incidence of clinically relevant arrhythmias in refractory focal epilepsy and to assess the potential of postictal arrhythmias as risk markers for sudden unexpected death in epilepsy (SUDEP).

Methods: We recruited people with refractory focal epilepsy without signs of ictal asystole and who had at least one focal seizure per month and implanted a loop recorder with 2-year follow-up. The devices automatically record arrhythmias. Read More

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http://dx.doi.org/10.1111/epi.16373DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6899995PMC
November 2019
1 Read
4.571 Impact Factor

Role of family history and clinical screening in the identification of families with idiopathic dilated cardiomyopathy in Johannesburg, South Africa.

S Afr Med J 2019 Aug 28;109(9):673-678. Epub 2019 Aug 28.

Division of Human Genetics, National Health Laboratory Service; and School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.

Background: Familial disease is implicated in 20 - 50% of cases of idiopathic dilated cardiomyopathy (IDCM) worldwide. The contribution of familial factors to IDCM in the Johannesburg area, South Africa, is unknown.

Objectives: To describe the demographic details of patients with IDCM who presented at Charlotte Maxeke Johannesburg Academic Hospital (CMJAH), and to determine if there is evidence of familial disease through family history assessment and clinical screening of relatives. Read More

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http://dx.doi.org/10.7196/SAMJ.2019.v109i9.13936DOI Listing
August 2019
1 Read

Comparing the Effect of Gabapentin, Ketamine, Dexmedetomidine, and Entonox on Pain Control in Burn Wound Dressing.

J Burn Care Res 2020 Jan;41(1):151-158

Department of Anesthesiology Critical Care and Pain Management, Kermanshah University of Medical Sciences, Kermanshah, Iran.

This study aimed to evaluate differences in the experience of pain, nausea, and vomiting, as well as the hemodynamic parameters including heart rate (HR) and blood pressure (BP) in burn patients across four pain treatment groups-i.e., gabapentin, ketamine, dexmedetomidine, and entonox. Read More

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http://dx.doi.org/10.1093/jbcr/irz142DOI Listing
January 2020
3 Reads
1.550 Impact Factor

Results of a phase 1 multicentre investigation of dexmedetomidine bolus and infusion in corrective infant cardiac surgery.

Br J Anaesth 2019 12 14;123(6):839-852. Epub 2019 Oct 14.

Department of Pediatric Anesthesiology, Perioperative and Pain Medicine, Texas Children's Hospital/Baylor College of Medicine, Houston, TX, USA. Electronic address:

Background: Dexmedetomidine (DEX) is increasingly used intraoperatively in infants undergoing cardiac surgery. This phase 1 multicentre study sought to: (i) determine the safety of DEX for cardiac surgery with cardiopulmonary bypass; (ii) determine the pharmacokinetics (PK) of DEX; (iii) create a PK model and dosing for steady-state DEX plasma levels; and (iv) validate the PK model and dosing.

Methods: We included 122 neonates and infants (0-180 days) with D-transposition of the great arteries, ventricular septal defect, or tetralogy of Fallot. Read More

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http://dx.doi.org/10.1016/j.bja.2019.06.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6993105PMC
December 2019
1 Read

Restrictive cardiomyopathy in a patient with systemic sclerosis and Fabry disease: a case-based review.

Rheumatol Int 2020 Mar 10;40(3):489-497. Epub 2019 Oct 10.

Internal Medicine, Universidad Libre, Cali, Colombia.

Systemic sclerosis (SSc) is a rare immune-mediated vasculopathy characterized by fibrosis of the skin and internal organs. Fabry disease (FD) is an X-linked lysosomal storage disorder caused by mutations in the GLA gene producing α-galactosidase-A enzyme (α-Gal A) deficiency. Being a systemic disease, cardiac involvement in FD has a high mortality rate due to heart failure and arrhythmia. Read More

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http://dx.doi.org/10.1007/s00296-019-04453-yDOI Listing
March 2020
1 Read

Cell atlas of the fetal human heart and implications for autoimmune-mediated congenital heart block.

Cardiovasc Res 2019 Oct 7. Epub 2019 Oct 7.

Laboratory for RNA Molecular Biology, The Rockefeller University, 1230 York Ave, Box 186, New York, NY, USA.

Aims: Investigating human heart development and applying this to deviations resulting in disease is incomplete without molecular characterization of the cell types required for its normal functioning. We investigated fetal human heart single-cell transcriptomes from midgestational healthy and anti-Ro associated congenital heart block (CHB) samples, respectively.

Methods And Results: Three healthy fetal human hearts (19th-22nd week of gestation) and one fetal heart affected by autoimmune-associated CHB (21st week of gestation) were subjected to enzymatic dissociation using the Langendorff preparation to obtain single cell suspensions followed by 10x Genomics- and Illumina-based single cell RNA-sequencing (scRNA-seq). Read More

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http://dx.doi.org/10.1093/cvr/cvz257DOI Listing
October 2019
1 Read
5.940 Impact Factor

A challenging ECG: a case of a lengthening PR interval.

Postgrad Med 2019 Nov 1;131(8):572-573. Epub 2019 Oct 1.

Department of Cardiology, Long Beach Veterans Affairs Medical Center, Long Beach, CA, USA.

A 62-year-old man presented to the emergency department with shortness of breath and chest tightness. His initial ECG appeared to have an ectopic P-wave with a lengthening PR interval consistent with second degree AV block - Mobitz Type I. But closer inspection showed a faster, independent atrial rate. Read More

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http://dx.doi.org/10.1080/00325481.2019.1669917DOI Listing
November 2019

Safety and efficacy of ozanimod versus interferon beta-1a in relapsing multiple sclerosis (RADIANCE): a multicentre, randomised, 24-month, phase 3 trial.

Lancet Neurol 2019 11 3;18(11):1021-1033. Epub 2019 Sep 3.

Neurologic Clinic and Policlinic, University Hospital and University of Basel, Basel, Switzerland.

Background: Ozanimod is a sphingosine 1-phosphate receptor modulator, which selectively binds to sphingosine 1-phosphate receptor subtypes 1 and 5 with high affinity. In the RADIANCE phase 2 study in participants with relapsing multiple sclerosis, ozanimod was associated with better efficacy than placebo on MRI measures and was well tolerated. The RADIANCE phase 3 study aimed to confirm the safety and efficacy of ozanimod versus interferon beta-1a in individuals with relapsing multiple sclerosis. Read More

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http://dx.doi.org/10.1016/S1474-4422(19)30238-8DOI Listing
November 2019
6 Reads

Predictors of pacing-dependency in patients with cardiovascular implantable electronic devices.

Cardiol J 2019 Sep 6. Epub 2019 Sep 6.

Department of Cardiology, University Marburg, Baldinger Straße, 35033 Marburg, Germany.

Background: Data on the prevalence and predictors for the development of pacing-dependency in patients with cardiovascular implantable electronic devices (CIEDs) are sparse.

Methods: Pacing-dependency defined as an absence of intrinsic rhythm of ≥ 30 bpm was determined in 802 consecutive patients with CIEDs who visited the documented pacemaker or implantable cardioverter-defibrillator outpatient clinic for routine follow-up.

Results: A total of 131 (16%) patients were found to be pacing-dependent 67 ± 70 months after CIED implant. Read More

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http://dx.doi.org/10.5603/CJ.a2019.0088DOI Listing
September 2019
3 Reads

Cardiac and Neuromuscular Features of Patients With LMNA-Related Cardiomyopathy.

Ann Intern Med 2019 Oct 3;171(7):458-463. Epub 2019 Sep 3.

Vita-Salute San Raffaele University and IRCCS San Raffaele Hospital, Milan, Italy (C.D., S.C.P., L.G., A.A., M.F., P.D.B., S.B., S.S.).

Background: Mutations in the LMNA (lamin A/C) gene have been associated with neuromuscular and cardiac manifestations, but the clinical implications of these signs are not well understood.

Objective: To learn more about the natural history of LMNA-related disease.

Design: Observational study. Read More

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http://dx.doi.org/10.7326/M18-2768DOI Listing
October 2019
3 Reads

Severe Hypoglycemia-Induced Fatal Cardiac Arrhythmias Are Mediated by the Parasympathetic Nervous System in Rats.

Diabetes 2019 11 22;68(11):2107-2119. Epub 2019 Aug 22.

Division of Endocrinology, Metabolism, and Diabetes, Department of Internal Medicine, University of Utah, Salt Lake City, UT

The contribution of the sympathetic nervous system (SNS) versus the parasympathetic nervous system (PSNS) in mediating fatal cardiac arrhythmias during insulin-induced severe hypoglycemia is not well understood. Therefore, experimental protocols were performed in nondiabetic Sprague-Dawley rats to test the SNS with ) adrenal demedullation and ) chemical sympathectomy, and to test the PSNS with ) surgical vagotomy, ) nicotinic receptor (mecamylamine) and muscarinic receptor (AQ-RA 741) blockade, and ) ex vivo heart perfusions with normal or low glucose, acetylcholine (ACh), and/or mecamylamine. In protocols 1-4, 3-h hyperinsulinemic (0. Read More

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http://dx.doi.org/10.2337/db19-0306DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118248PMC
November 2019
3 Reads

Crataegus mexicana (Tejocote) Exposure Associated with Cardiotoxicity and a Falsely Elevated Digoxin Level.

J Med Toxicol 2019 Oct 12;15(4):295-298. Epub 2019 Aug 12.

Division of Emergency Medicine, Seattle Children's Hospital, University of Washington, MB.7.520 - Emergency Medicine , 4800 Sand Point Way NE, Seattle, WA, 98105, USA.

Introduction: A species of hawthorn, Crataegus mexicana (tejocote), has been marketed as a weight-loss supplement that is readily available for purchase online. While several hawthorn species have shown clinical benefit in the treatment of heart failure owing to their positive inotropic effects, little is known about hawthorn, and tejocote in particular, when consumed in excess. We describe a case of tejocote exposure from a weight-loss supplement resulting in severe cardiotoxicity. Read More

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http://dx.doi.org/10.1007/s13181-019-00727-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6825057PMC
October 2019
3 Reads

Establishing 24-hour Holter reference intervals for clinically healthy puppies.

Res Vet Sci 2019 Aug 11;125:253-255. Epub 2019 Jul 11.

Department of Veterinary Clinical Sciences, College of Veterinary Medicine, PO Box 647060, Washington State University, Pullman, WA 99164-7060, USA.

Normal Holter reference intervals have not been established for dogs <1 year of age. This lack of Holter reference intervals inhibits the ability to screen puppies for early indicators of heart disease, especially in breeds that have inherited cardiac arrhythmias (e.g. Read More

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http://dx.doi.org/10.1016/j.rvsc.2019.07.010DOI Listing
August 2019
6 Reads

Beyond first-degree heart block in the diagnosis of acute rheumatic fever.

Cardiol Young 2019 Jun 14;29(6):744-748. Epub 2019 Jun 14.

KidzFirst Children's Hospital,South Auckland,New Zealand.

Objectives: First-degree heart block is a minor manifestation of acute rheumatic fever. Second and third degree heart block and junctional rhythms occur less commonly. We report patients presenting with these latter three electrocardiographic abnormalities and investigate their diagnostic utility. Read More

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http://dx.doi.org/10.1017/S104795111900026XDOI Listing
June 2019
9 Reads

Contemporary practice pattern of permanent pacing for conduction disorders in inferior ST-elevation myocardial infarction.

Clin Cardiol 2019 Aug 7;42(8):728-734. Epub 2019 Jun 7.

Devision of Cardiovascular Medicine, University of Florida, Jacksonville, Florida.

Background: Currently, there is no clear consensus regarding the optimal waiting period before permanent pacemaker implantation in patients with conduction disorders following an inferior myocardial infarction.

Hypothesis: We aimed to elucidate the contemporary practice pattern of pacing, especially the timing of pacemaker implantation, for sinoatrial node and atrioventricular (AV) conduction disorders following an inferior ST-elevation myocardial infarction (STEMI).

Methods: Using the National Inpatient Sample database from 2010 to 2014, we identified patients with a primary diagnosis of inferior STEMI. Read More

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http://dx.doi.org/10.1002/clc.23210DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6671775PMC
August 2019
10 Reads

Evaluation of heart rate variability and behavior of electrocardiographic parameters in dogs affected by chronic Monocytic Ehrlichiosis.

PLoS One 2019 24;14(5):e0216552. Epub 2019 May 24.

Department of Veterinary Clinics, São Paulo State University (Unesp), School of Veterinary Medicine and Animal Science, Botucatu, São Paulo, Brazil.

Canine Monocytic Ehrlichiosis (CME) is a systemic disease prevalent in the entire world caused by the obligate intracellular bacteria Ehrlichia canis. The occurrence of myocarditis with a high prevalence of arrhythmias in dogs affected by this disease in the cytopenic phase has already been proven. This study aims to evaluate the concentrations of CK MB, cTnI and NT-proBNP in dogs affected by Ehrlichia canis in the chronic phase since the intense stimulation of the immune system can lead to myocarditis; to evaluate if the condition can lead to arrhythmic events and, if so, define their frequency and classification through conventional and ambulatory electrocardiogram tests (Holter method) for a period of 24 hours; to analyze heart rate variability in the time domain and whether the condition can lead to autonomic imbalance; and to determine the survival rate of affected dogs, identifying possible risk factors for mortality at this stage of the disease. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0216552PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534309PMC
January 2020
26 Reads

Risk Factors Associated With Atrioventricular Block.

JAMA Netw Open 2019 05 3;2(5):e194176. Epub 2019 May 3.

Electrophysiology Section, Division of Cardiology, University of California, San Francisco.

Importance: Pacemaker implantations as a treatment for atrioventricular (AV) block are increasing worldwide. Prevention strategies for AV block are lacking because modifiable risk factors have not yet been identified.

Objective: To identify risk factors for AV block in community-dwelling individuals. Read More

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http://dx.doi.org/10.1001/jamanetworkopen.2019.4176DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6632153PMC
May 2019
22 Reads

The influence of anesthesia with isoflurane on the pulmonary and aortic blood flow of Racing Pigeons ( f. domestica) measured by pulsed wave Doppler echocardiography.

Open Vet J 2019 04 7;9(1):18-26. Epub 2019 Feb 7.

Clinic for Small Mammals, Reptiles and Birds, University of Veterinary Medicine Hannover, Foundation, D-30559 Hannover, Germany.

Doppler echocardiographic examinations are an important technique for evaluating the blood flow also in avian cardiology. The influence of anesthesia on the blood flow in the heart is in detail unknown for the most avian species. The present study investigated the influence of an isoflurane anesthesia on the systolic blood flow of the aorta and the pulmonary artery in the area of the heart valves examined by pulsed wave Doppler sonography in Racing Pigeons ( f. Read More

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http://dx.doi.org/10.4314/ovj.v9i1.4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6500857PMC
April 2019
9 Reads

Lyme carditis presenting as atrial fibrillation.

BMJ Case Rep 2019 Apr 29;12(4). Epub 2019 Apr 29.

Department of Cardiology, Rochester Regional Health, Rochester, New York, USA.

The incidence of Lyme disease in the USA is 8 per 100 000 cases and 95% of those occur in the Northeastern region. Cardiac involvement occurs in only 1% of untreated patients. We describe the case of a 46-year-old man who presented with chest pressure, dyspnoea, palpitations and syncope. Read More

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http://dx.doi.org/10.1136/bcr-2018-228975DOI Listing
April 2019
10 Reads

Transvenous dual-chamber pacemaker implantation in patients with persistent left superior vena cava.

BMC Cardiovasc Disord 2019 04 29;19(1):100. Epub 2019 Apr 29.

Arrhythmia Department, Fuwai Hospital Chinese Academy of Medical Sciences, Shenzhen, 518057, Guangdong, China.

Background: Persistent left superior vena cava (PLSVC) is a rare congenital vascular anomaly. Permanent pacemaker implantation (PPI) in patients with PLSVC can be challenging because of the venous anomalies. We reported a case series of patients with PLSVC who underwent PPI with double active fixation leads. Read More

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http://dx.doi.org/10.1186/s12872-019-1082-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6489345PMC
April 2019
9 Reads

High Prevalence of Proarrhythmic Events in Patients With History of Atrial Fibrillation Undergoing a Rhythm Control Strategy: A Retrospective Study.

J Clin Med Res 2019 May 14;11(5):345-352. Epub 2019 Apr 14.

Division of Geriatrics, Clinic "S. Maria del Pozzo", via Pomigliano 40, Somma Vesuviana, Italy.

Background: A retrospective study was undertaken to evaluate the respective prevalence of proarrhythmic events depending on various therapeutic regimens within a population of patients with history of atrial fibrillation (AF) undergoing a rhythm control strategy.

Methods: Inclusion criterion was the presence of AF in the patient's clinical history, whose cardioversion had been followed by the adoption of rhythm control strategy. The primary endpoint was the determination of the respective prevalences of paradoxical arrhythmias in the various therapeutic groups. Read More

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http://dx.doi.org/10.14740/jocmr3805DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469886PMC
May 2019
8 Reads

Frequency and characteristics of exercise-induced second-degree atrioventricular block in patients undergoing stress testing.

J Electrocardiol 2019 May - Jun;54:54-60. Epub 2019 Mar 14.

Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, United States of America.

Background: Spontaneous second-degree atrioventricular block induced by exercise (Ex2AVB) is rare, but it can cause profound exercise intolerance.

Objective: We sought to determine the frequency of Ex2AVB in our exercise testing practice and to describe characteristics of patients with Ex2AVB. We hypothesized that the number of patients would be small, but they would require invasive treatment. Read More

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http://dx.doi.org/10.1016/j.jelectrocard.2019.03.009DOI Listing
March 2019
13 Reads

[Abnormal ECG findings in athletes].

Authors:
Pietro Delise

G Ital Cardiol (Rome) 2019 Apr;20(4):242-253

U.O. Cardiologia, Ospedale P. Pederzoli, Peschiera del Garda (VR).

Athlete's heart, as a consequence of exercise training, is characterized by hypervagotonia and enlargement of cardiac chambers. Such modifications influence the electrocardiogram. In fact, athletes frequently present with common cardiac alterations, including sinus bradycardia, first and second degree atrioventricular block, increased QRS voltage, and early repolarization. Read More

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http://www.giornaledicardiologia.it/articoli.php?archivio=ye
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http://dx.doi.org/10.1714/3126.31077DOI Listing
April 2019
84 Reads

A 2:1 atrioventricular block presenting paradoxical ventriculophasic response.

Ann Noninvasive Electrocardiol 2019 07 19;24(4):e12642. Epub 2019 Mar 19.

Department of Cardiology, Kizawa Memorial Hospital, Minokamo, Japan.

Ventriculophasic response (VR) is defined as the shortening of the sinus cycle length in the setting of greater than second-degree atrioventricular (AV) block. Typically, the PP intervals interposing a QRS complex are shorter than those without a QRS complex. Paradoxical VR is a rare clinical entity. Read More

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http://dx.doi.org/10.1111/anec.12642DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6931805PMC
July 2019
6 Reads

Cardiac Arrhythmias in Horses.

Authors:
Gunther van Loon

Vet Clin North Am Equine Pract 2019 Apr 11;35(1):85-102. Epub 2019 Mar 11.

Department of Large Animal Internal Medicine, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, Merelbeke 9820, Belgium. Electronic address:

Arrhythmias are common in horses. Sinus arrhythmia and first- and second-degree atrioventricular block are frequently found physiologic arrhythmias, but should immediately disappear after stress or exercise. Atrial premature depolarizations are usually not associated with poor performance, but are a potential trigger for atrial fibrillation. Read More

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http://dx.doi.org/10.1016/j.cveq.2018.12.004DOI Listing
April 2019
8 Reads

Second-degree interatrial block: A case series.

J Electrocardiol 2019 May - Jun;54:18-21. Epub 2019 Feb 7.

Division of Cardiology, Kingston Health Science Center, Queen's University, Kingston, Ontario, Canada.

Advanced interatrial block (IAB) (P-wave ≥120 ms and biphasic P-wave in leads II, III and aVF) is a prevalent ECG pattern frequently associated with supraventricular arrhythmias and stroke, especially in patients with structural heart disease. Intermittent IAB is a much more poorly defined electrocardiographic entity with uncertain clinical significance. In this case series, we review and analyze eight cases of second degree intermittent IAB. Read More

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http://dx.doi.org/10.1016/j.jelectrocard.2019.02.001DOI Listing
February 2019
8 Reads

Assessment of atrioventricular conduction by echocardiography and magnetocardiography in normal and anti-Ro/SSA-antibody-positive pregnancies.

Ultrasound Obstet Gynecol 2019 Nov;54(5):625-633

Department of Medical Physics, The University of Wisconsin, Madison, WI, USA.

Objectives: The objectives of this study were, first, to evaluate the association between fetal echocardiographic atrioventricular (AV) and magnetocardiographic (fMCG) PR intervals at different gestational ages (GAs) in normal and anti-Ro/SSA-antibody-positive pregnancies; second, to determine if PR interval could be predicted by AV interval; and third, to assess the neonatal outcome of fetuses with prolonged AV and PR intervals, with the goal of developing criteria for fetal first-degree AV block (AVB-I).

Methods: This was a retrospective study of anti-Ro/SSA-antibody-positive pregnancies (cases) and controls that underwent fMCG and fetal echocardiography at the same recording session. Cardiac cycle length, GA and AV (by mitral inflow/aortic outflow Doppler) and PR (by fMCG) intervals were measured. Read More

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http://dx.doi.org/10.1002/uog.20245DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699937PMC
November 2019
3 Reads

Case report: Atrioventricular block after transcatheter atrial septal closure using the Figulla® Flex II ASD occluder.

Catheter Cardiovasc Interv 2019 04 17;93(5):E298-E301. Epub 2019 Feb 17.

Department of Paediatric Cardiology, Japan Community Health Organization Chukyo Hospital, Nagoya, Japan.

We report a 7-year-old male patient who developed severe atrioventricular block after transcatheter closure of the atrial septal defect with an Occlutech Figulla® Flex II ASD occluder (FSO). He had a small aortic rim and the defect measuring 22.3 mm by balloon sizing. Read More

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http://dx.doi.org/10.1002/ccd.28148DOI Listing
April 2019
29 Reads

Second degree heart block following the administration of dexmedetomidine.

J Clin Anesth 2019 08 9;55:103-104. Epub 2019 Jan 9.

Division of Pediatric Critical Care Medicine, Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, Madison, WI 53792, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jclinane.2018.12.052DOI Listing
August 2019
7 Reads

Resolution of fetal second-degree atrioventricular block.

J Electrocardiol 2018 Nov - Dec;51(6):945-947. Epub 2018 Aug 17.

University of Massachusetts Medical School, Department of Pediatric Cardiology, 55 Lake Avenue North, Worcester, MA 01655, United States of America.

Fetal atrioventricular (AV) block is a rare and potentially devastating condition. Most commonly fetal AV block is mediated by maternal lupus antibodies which cause irreversible damage to the AV node. For many fetuses, the only potential intervention is premature delivery and highly invasive pacemaker implantation. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00220736183048
Publisher Site
http://dx.doi.org/10.1016/j.jelectrocard.2018.08.020DOI Listing
October 2019
42 Reads

Dysrhythmias in patients with a complete atrioventricular septal defect: From surgery to early adulthood.

Congenit Heart Dis 2019 Mar 28;14(2):280-287. Epub 2018 Nov 28.

Department of Cardiothoracic Surgery, Erasmus University Medical Center, Rotterdam, The Netherlands.

Objective: Outcomes after surgical repair of complete atrioventricular septal defect (cAVSD) have improved. With advancing age, the risk of development of dysrhythmias may increase. The aims of this study were to (1) examine development of sinus node dysfunction (SND), atrial and ventricular tachyarrhythmias, and (2) study progression of atrioventricular conduction abnormalities in young adult patients with repaired cAVSD. Read More

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http://dx.doi.org/10.1111/chd.12724DOI Listing
March 2019
38 Reads