1,445 results match your criteria Heart Block First Degree


[Pulmonary embolism and complete atrioventricular block].

J Med Vasc 2018 Dec 27;43(6):375-378. Epub 2018 Sep 27.

Institut de cardiologie d'Abidjan, 01 BP V, 206 Abidjan, Côte d'Ivoire.

Complete atrioventricular block is a rare complication of pulmonary embolism. We describe the case of a black African patient, aged 42 years, who presented to the emergency department of Abidjan Heart Institute for sudden onset dyspnea and hemoptysis. ECG revealed a third degree atrioventricular block. Read More

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http://dx.doi.org/10.1016/j.jdmv.2018.08.002DOI Listing
December 2018

Heart involvement in patients with myotonic dystrophy type 2.

Acta Neurol Belg 2018 Dec 7. Epub 2018 Dec 7.

Neurology Clinic, Clinical Centre of Serbia, School of Medicine, University of Belgrade, 6, Dr Subotica Street, Belgrade, 11000, Serbia.

Myotonic dystrophy type 2 (DM2) is a slowly progressive, autosomal-dominant disease. This is a multisystemic disorder that affects the heart, which is one of the main causes of morbidity and mortality in DM2. The aim of the study was to define cardiac impairments in patients with DM2 and its association with sociodemographic and clinical features of patients. Read More

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http://link.springer.com/10.1007/s13760-018-1052-3
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http://dx.doi.org/10.1007/s13760-018-1052-3DOI Listing
December 2018
2 Reads

Transcatheter Closure of Perimembranous Ventricular Septal Defects in Children using a Wire-Drifting Technique.

Clinics (Sao Paulo) 2018 Nov 29;73:e371. Epub 2018 Nov 29.

Department of Structural Heart Disease, The First Affiliated Hospital of Xi'an Jiaotong University, Shaanxi Province, China.

Objective: Explore the feasibility and safety of transcatheter closure of perimembranous ventricular septal defects using a wire-drifting technique (WT) in children.

Methods: We retrospectively analyzed 121 pediatric patients diagnosed with perimembranous ventricular septal defects who underwent interventional treatment at the First Affiliated Hospital of Xi'an Jiaotong University from Dec 2011 to Dec 2014. Based on the method used for arteriovenous loop establishment during the procedure, the patients were divided into a conventional technique (CT) group and a WT group. Read More

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http://dx.doi.org/10.6061/clinics/2018/e371DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238823PMC
November 2018
2 Reads

Dysrhythmias in patients with a complete atrioventricular septal defect: From surgery to early adulthood.

Congenit Heart Dis 2018 Nov 28. Epub 2018 Nov 28.

Department of Cardiothoracic Surgery, Erasmus University Medical Center, Rotterdam, The Netherlands.

Objective: Outcomes after surgical repair of complete atrioventricular septal defect (cAVSD) have improved. With advancing age, the risk of development of dysrhythmias may increase. The aims of this study were to (1) examine development of sinus node dysfunction (SND), atrial and ventricular tachyarrhythmias, and (2) study progression of atrioventricular conduction abnormalities in young adult patients with repaired cAVSD. Read More

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http://dx.doi.org/10.1111/chd.12724DOI Listing
November 2018
1 Read

Prenatal heart block screening in mothers with SSA/SSB autoantibodies: Targeted screening protocol is a cost-effective strategy.

Congenit Heart Dis 2018 Nov 16. Epub 2018 Nov 16.

Children's Heart Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.

Objective: Maternal anti-Ro/SSA and anti-La/SSB antibodies can lead to fetal complete heart block (CHB). Current guidelines recommend weekly echocardiographic screening between 16 and 28 weeks gestation. Given the cost of screening and the rarity of conduction abnormalities in fetuses of mothers with low anti-Ro levels (<50 U/mL), we sought to identify a strategy that optimizes resource utilization. Read More

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http://doi.wiley.com/10.1111/chd.12713
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http://dx.doi.org/10.1111/chd.12713DOI Listing
November 2018
5 Reads

Disruption of RHOA-ROCK Signaling Results in Atrioventricular Block and Disturbed Development of the Putative Atrioventricular Node.

Anat Rec (Hoboken) 2018 Nov 9. Epub 2018 Nov 9.

Department of Anatomy & Embryology, Leiden University Medical Center, Leiden, The Netherlands.

The RHOA-ROCK signaling pathway is involved in numerous developmental processes, including cell proliferation, differentiation and migration. RHOA is expressed in the atrioventricular node (AVN) and altered expression of RHOA results in atrioventricular (AV) conduction disorders in mice. The current study aims to detect functional AVN disorders after disturbing RHOA-ROCK signaling in chicken embryos. Read More

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http://doi.wiley.com/10.1002/ar.23912
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http://dx.doi.org/10.1002/ar.23912DOI Listing
November 2018
6 Reads

Home Monitoring for Fetal Heart Rhythm During Anti-Ro Pregnancies.

J Am Coll Cardiol 2018 Oct;72(16):1940-1951

Division of Cardiology, Department of Pediatrics, Hospital for Sick Children, Toronto, Canada.

Background: Fetal atrioventricular block (AVB) occurs in 2% to 4% of anti-Ro antibody-positive pregnancies and can develop in <24 h. Only rarely has standard fetal heart rate surveillance detected AVB in time for effective treatment.

Objectives: Outcome of anti-Ro pregnancies was surveilled with twice-daily home fetal heart rate and rhythm monitoring (FHRM) and surveillance echocardiography. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S07351097183694
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http://dx.doi.org/10.1016/j.jacc.2018.07.076DOI Listing
October 2018
15 Reads

A Rare Case of Second Degree Mobitz Type II AV Block Associated with Cocaine Use.

Am J Med Case Rep 2018 21;6(7):146-148. Epub 2018 Aug 21.

Department of Internal Medicine, State University of New York Downstate Medical Center, Brooklyn, New York, U.S.A- 11203.

Cocaine is a commonly abused illicit drug in the United States. The complex effects of cocaine on the conduction system of the human heart has not been completely understood. Cocaine acts as a sympathomimetic by inhibition of reuptake of neuronal catecholamines, leading mostly to tachyarrhythmias on presentation. Read More

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http://pubs.sciepub.com/ajmcr/6/7/7/index.html
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http://dx.doi.org/10.12691/ajmcr-6-7-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173318PMC
August 2018
2 Reads

Dynamic Electrocardiography is Useful in the Diagnosis of Persistent Atrial Fibrillation Accompanied with Second-Degree Atrioventricular Block.

Acta Cardiol Sin 2018 Sep;34(5):409-416

Department of Cardiology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310003, China.

Background: Periodic electrocardiography (ECG) at every clinical visit is generally performed for heart rhythm surveillance, and 24-h Holter ECG is usually used as the gold standard. We aimed to investigate the electrocardiographic features of persistent atrial fibrillation (AF) accompanied with second-degree atrioventricular block (AVB).

Methods: From October 2012 to November 2015, 204 patients with an RR interval > 2. Read More

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http://dx.doi.org/10.6515/ACS.201809_34(5).20180326EDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160510PMC
September 2018
2 Reads
0.840 Impact Factor

[Bachmann bundle pacing].

Herz 2018 Nov;43(7):584-595

Klinik für Innere Medizin - Kardiologie, Diabetologie & Nephrologie, Evangelisches Klinikum Bethel, Burgsteig 13, 33617, Bielefeld, Deutschland.

In pacemaker and ICD therapy, atrial leads are usually implanted in the right atrial appendage (RAA). This is easy but associated with a risk of negative hemodynamic and electrophysiological effects. Atrial depolarization, atrial contraction, and atrioventricular conduction can be delayed and desynchronized by RAA pacing leading to atrial fibrillation, pacing-induced long first-degree AV block, right ventricular pacing and the development of heart failure. Read More

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http://dx.doi.org/10.1007/s00059-018-4755-6DOI Listing
November 2018
7 Reads

Rapid Progression of Heart Failure in a Patient with Idiopathic Inflammatory Myopathy.

Am J Med Case Rep 2018 23;6(8):157-160. Epub 2018 Aug 23.

Divisions of Cardiovascular Disease and Rheumatology, Department of Internal Medicine, State University of New York, Downstate Medical Center, Brooklyn, New York, U.S.A- 11203.

Idiopathic inflammatory myopathy (IIM) is a rare autoimmune myopathy that includes polymyositis, dermatomyositis, inclusion body myositis and autoimmune necrotizing myositis. Cardiac involvement was considered a rare occurrence in IIM however, recent reports suggests that cardiac involvement is a common feature and portends poor prognosis as it is usually encountered in advanced disease. IIM leads to myocarditis with subsequent development of myocardial fibrosis, cardiac conduction system disease and cardiomyopathy resulting in both systolic and diastolic heart failure. Read More

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http://dx.doi.org/10.12691/ajmcr-6-8-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138443PMC
August 2018
5 Reads

Association between decreasing estimated glomerular filtration rate and risk of cardiac conduction defects in patients with type 2 diabetes.

Diabetes Metab 2018 12 5;44(6):473-481. Epub 2018 Sep 5.

Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, University and Azienda Ospedaliera Universitaria Integrata of Verona, Piazzale Stefani, 1, 37126 Verona, Italy. Electronic address:

Aim: We aimed to assess the association between decreasing estimated glomerular filtration rate (eGFR) or abnormal albuminuria and the risk of certain cardiac conduction defects in patients with type 2 diabetes mellitus (T2DM).

Methods: We examined a hospital-based sample of 923 patients with T2DM discharged from our Division of Endocrinology over the years 2007-2014. Standard electrocardiograms (ECGs) were performed in all patients. Read More

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http://dx.doi.org/10.1016/j.diabet.2018.08.007DOI Listing
December 2018
1 Read

Morphological Substrates for Atrial Arrhythmogenesis in a Heart With Atrioventricular Septal Defect.

Front Physiol 2018 23;9:1071. Epub 2018 Aug 23.

School of Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, United Kingdom.

Due to advances in corrective surgery, congenital heart disease has an ever growing patient population. Atrial arrhythmias are frequently observed pre- and post-surgical correction. Pharmaceutical antiarrhythmic therapy is not always effective, therefore many symptomatic patients undergo catheter ablation therapy. Read More

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http://dx.doi.org/10.3389/fphys.2018.01071DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115687PMC
August 2018
3 Reads

Second-degree interatrial block: Brief review and concept.

Ann Noninvasive Electrocardiol 2018 Nov 2;23(6):e12583. Epub 2018 Sep 2.

National Academy of Medicine, Buenos Aires, Argentina.

The advanced interatrial block (A-IAB) (P ≥ 120 ms plus ± pattern in II, III and aVF) corresponds at atrial level, to right or left advanced bundle branch block at ventricular level, and it is well known that these patterns may be seen transiently in relation to taquicardia or bradycardia (tachycardia or bradycardia dependent right or left bundle branch block). We present for the first time, the same phenomenon at atrial level. In one case, the A-IAB appears in relation to tachycardization and in the other disappears during a pause induced by ventricular premature complex. Read More

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http://dx.doi.org/10.1111/anec.12583DOI Listing
November 2018
3 Reads

The prevention, screening and treatment of congenital heart block from neonatal lupus: a survey of provider practices.

Rheumatology (Oxford) 2018 07;57(suppl_5):v9-v17

Division of Rheumatology, New York University School of Medicine, NY, USA.

Objective: To survey an international sample of providers to determine their current practices for the prevention, screening, and treatment of congenital heart block (CHB) due to maternal Ro/SSA antibodies.

Methods: A survey was designed by the organizing committee of the 9th International Conference of Reproduction, Pregnancy and Rheumatic Diseases. It was sent to attendants of the conference and authors of recent publications or abstracts at ACR 2012, 2013 or 2014 on rheumatic diseases and pregnancy. Read More

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http://dx.doi.org/10.1093/rheumatology/key141DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099126PMC
July 2018
13 Reads

"First-degree AV block-a benign entity?" Insertable cardiac monitor in patients with 1st-degree AV block reveals presence or progression to higher grade block or bradycardia requiring pacemaker implant.

J Interv Card Electrophysiol 2018 Aug 13;52(3):303-306. Epub 2018 Aug 13.

Cardiovascular Center, University Hospital Zurich, Zurich, Switzerland.

Background: First-degree AV block has in the past generally been considered a benign condition. A few recent studies have shown that 1st-degree AV block is associated with an increased risk for heart failure, pacemaker (IPG) implantation, and death. We investigated the outcomes of patients who received an insertable cardiac monitor (ICM) (Medtronic Reveal XT®) within the scope of the INSIGHT XT study and had 1st-degree AV block at baseline. Read More

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http://dx.doi.org/10.1007/s10840-018-0439-7DOI Listing
August 2018
2 Reads

Lyme Carditis: A Case Report and Review of Management.

Hosp Pharm 2018 Jul 2;53(4):263-265. Epub 2018 Jan 2.

University of Pittsburgh Medical Center Mercy, PA, USA.

A case report of a patient who presented with an acute onset, fluctuating atrioventricular (AV) block and was diagnosed with Lyme carditis is presented. A 55-year-old man with progressively worsening generalized malaise, flu-like symptoms, dyspnea on exertion, and near syncope was admitted with bradycardia (heart rate was between 20 and 30 beats per minute upon admission). He endorsed having several tick bites after which he developed erythema migrans on his arm and abdomen. Read More

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http://dx.doi.org/10.1177/0018578717749927DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050884PMC
July 2018
1 Read

Cryoablation of the right anteroseptal or midseptal accessory pathways in children: A 2-year single-center experience.

Authors:
He Jiang Xiaomei Li

Pacing Clin Electrophysiol 2018 09 26;41(9):1123-1128. Epub 2018 Jul 26.

School of Medicine, Tsinghua University & Department of Pediatric Cardiology, Heart Center, The First Hospital of Tsinghua University, Beijing, China.

Background: Radiofrequency catheter ablation (RFCA) in the septum close to the atrioventricular node or His bundle has an increased risk of irreversible complications. Cryothermal energy has the advantages of reversible cryomapping and increased catheter stability. The study aims to evaluate the efficacy and safety of cryoablation of the right anteroseptal or midseptal accessory pathways (APs) in pediatric patients. Read More

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http://dx.doi.org/10.1111/pace.13438DOI Listing
September 2018
1 Read

Electrocardiographic abnormalities in Chagas disease in the general population: A systematic review and meta-analysis.

PLoS Negl Trop Dis 2018 06 13;12(6):e0006567. Epub 2018 Jun 13.

Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.

Background: Chagas disease (CD) is a major public health concern in Latin America and a potentially serious emerging threat in non-endemic countries. Although the association between CD and cardiac abnormalities is widely reported, study design diversity, sample size and quality challenge the information, calling for its update and synthesis, which would be very useful and relevant for physicians in non-endemic countries where health care implications of CD are real and neglected. We performed to systematically review and meta-analyze population-based studies that compared prevalence of overall and specific ECG abnormalities between CD and non-CD participants in the general population. Read More

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https://dx.doi.org/10.1371/journal.pntd.0006567
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http://dx.doi.org/10.1371/journal.pntd.0006567DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999094PMC
June 2018
8 Reads

Safety of ticagrelor in patients with baseline conduction abnormalities: A PLATO (Study of Platelet Inhibition and Patient Outcomes) analysis.

Am Heart J 2018 Aug 7;202:54-60. Epub 2018 May 7.

Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA. Electronic address:

Background: Although bradyarrhythmias have been observed with ticagrelor and its use with advanced atrioventricular block is not recommended, questions arise regarding its use in patients with mild conduction abnormalities. The objectives were to compare rates of clinically relevant arrhythmias in relation to any mild baseline conduction abnormality in patients with acute coronary syndrome randomized to ticagrelor versus clopidogrel.

Methods: We included all subjects in the electrocardiographic (ECG) substudy of the Platelet Inhibition and Patient Outcomes trial, excluding those with missing baseline ECG or with a pacemaker at baseline (N = 15,460). Read More

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http://dx.doi.org/10.1016/j.ahj.2018.04.020DOI Listing
August 2018
11 Reads

Low-energy ablation of anteroseptal accessory pathways in two dogs.

J Vet Cardiol 2018 Aug 30;20(4):285-293. Epub 2018 May 30.

Department of Clinical Sciences, Cornell University, Ithaca, NY 14853, USA.

In humans, accessory pathways (APs) in an anteroseptal and midseptal position are often challenging to ablate because of their close proximity with the conduction pathways of the atrioventricular junction. The use of low-energy ablation techniques can be useful to reduce the risk of permanently damaging the atrioventricular node and the His bundle. This report describes the use of low-energy radiofrequency catheter ablation to successfully and permanently ablate anteroseptal APs in two dogs with orthodromic atrioventricular reciprocating tachycardia. Read More

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http://dx.doi.org/10.1016/j.jvc.2018.05.001DOI Listing
August 2018
1 Read

Glibenclamide Prevents Hypoglycemia-Induced Fatal Cardiac Arrhythmias in Rats.

Endocrinology 2018 Jul;159(7):2614-2620

Division of Endocrinology, Metabolism, and Diabetes, Department of Internal Medicine, University of Utah, Salt Lake City, Utah.

Sulfonylureas increase the incidence of severe hypoglycemia in people with type 2 diabetes and might increase the risk of sudden cardiac death. Sulfonylureas stimulate insulin secretion by closing pancreatic ATP-sensitive potassium ion (KATP) channels. To investigate the role of KATP channel modulators on cardiac arrhythmias and mortality in the setting of severe hypoglycemia, adult Sprague-Dawley rats underwent hyperinsulinemic (0. Read More

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http://dx.doi.org/10.1210/en.2018-00419DOI Listing
July 2018
2 Reads

Chagasic cardiomyopathy and Pompe disease: case report.

Am J Cardiovasc Dis 2018 5;8(2):19-23. Epub 2018 Apr 5.

Hospital das Clínicas da UFPE, Department of Cardiology Brazil.

Background: Pompe disease is a lysosomal storage disease with an autosomal recessive inheritance characterized by an insufficient activity of the acid alpha-glucosidase enzyme. The incidence varies from 1:40000 to 1:200000 live births and cardiac involvement in adults is rare. Chagas disease is an infection caused by the protozoan Trypanosoma cruzi, in which one-third of the cases progress to the chronic form, and may lead to cardiac involvement, usually from the fifth decade of life onwards. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944812PMC
April 2018
3 Reads

Primary central sleep apnea and anesthesia: a retrospective case series.

Can J Anaesth 2018 Aug 1;65(8):884-892. Epub 2018 May 1.

Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, 200 First St SW, Rochester, MN, 55905, USA.

Purpose: Primary (idiopathic) central sleep apnea (PCSA) is a rare central sleep-related breathing disorder characterized by increased chemoreceptor sensitivity to partial pressure of carbon dioxide, which manifests as hyperventilation followed by apnea during non-rapid eye movement sleep. The purpose of this retrospective study was to describe the postoperative course of patients who had PCSA and underwent procedures requiring anesthetic management.

Methods: Patients who received a diagnosis of PCSA at our institution and required procedural anesthesia between 1 January 2010 and 1 June 2016 underwent a comprehensive review of their health records with a focus on identifying respiratory complications. Read More

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http://dx.doi.org/10.1007/s12630-018-1144-9DOI Listing
August 2018
2 Reads

Acute Pediatric Colchicine Toxicity is Associated with Marked Bradydysrhythmias.

J Emerg Med 2018 09 29;55(3):e65-e69. Epub 2018 May 29.

Division of Cardiology, Department of Pediatrics, Rush University Medical College, Chicago, Illinois.

Background: Colchicine ingestion is rare but highly lethal. Patients usually die of multiorgan failure and cardiogenic shock. Colchicine is not only associated with depressed myocardial function but also with fatal heart rhythm disturbances, such as complete heart block, ventricular tachycardia, and asystole. Read More

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http://dx.doi.org/10.1016/j.jemermed.2018.03.004DOI Listing
September 2018
1 Read

Transient left anterior and septal fascicular blocks after self-expandable percutaneous transcatheter aortic valve implantation.

Ann Noninvasive Electrocardiol 2018 Apr 19:e12553. Epub 2018 Apr 19.

Heart Center, Tampere University Hospital and Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland.

Transcatheter aortic valve implantation (TAVI) is indicated in severe symptomatic aortic stenosis, when there is intermediate-high surgical risk, or a condition considered inoperable, as in the case of "porcelain aorta" that could turn clamping or cannulation of the ascending aorta hazardous in open-heart surgery. Among the complications of this less invasive procedure, intraventricular conduction disorders subsequent to the procedure stand out. TAVI causes worsening of intraventricular dromotropic disorders in more than 75% of the cases, with the presence of preexisting right bundle branch block and first-degree atrioventricular block, deep prosthesis implant, male gender, size of the aortic annulus smaller than the prosthesis, and porcelain aorta being predictive of requirement for permanent pacemaker implant. Read More

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http://dx.doi.org/10.1111/anec.12553DOI Listing
April 2018
6 Reads

Severe brady-arrhythmias in systemic lupus erythematosus: prevalence, etiology and associated factors.

Lupus 2018 Aug 17;27(9):1415-1423. Epub 2018 Apr 17.

1 Centre for Prognosis Studies in Rheumatic Diseases, Toronto Lupus Clinic, University Health Network, Toronto, Canada.

Background Severe brady-arrhythmias, requiring a permanent pacemaker (PPM), have been sparsely reported in systemic lupus erythematosus (SLE). The aim of this study was to describe the characteristics of such arrhythmias in a defined lupus cohort. Patients and methods The database of the Toronto Lupus Clinic ( n = 1366) was searched for patients who received a PPM. Read More

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http://dx.doi.org/10.1177/0961203318770526DOI Listing
August 2018
3 Reads

European Society of Cardiology-Proposed Diagnostic Echocardiographic Algorithm in Elective Patients with Clinical Suspicion of Infective Endocarditis: Diagnostic Yield and Prognostic Implications in Clinical Practice.

J Cardiovasc Echogr 2018 Jan-Mar;28(1):26-31

Department of Cardiology, Policlinico University Hospital, Modena and Reggio Emilia University, Modena, Italy.

Background: Echocardiography plays a central role in diagnosing infective endocarditis (IE). Accordingly, the European Society of Cardiology (ESC) has proposed a diagnostic echocardiographic algorithm. However, new studies are still needed to evaluate the degree of implementation of these guidelines in clinical practice and their consequences on incidence and prognosis of IE. Read More

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http://dx.doi.org/10.4103/jcecho.jcecho_49_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5875132PMC
April 2018
5 Reads

Clinical and electrocardiographic presentations of transient trifascicular block in three cats.

J Vet Cardiol 2018 Jun 20;20(3):204-212. Epub 2018 Mar 20.

Cornell University College of Veterinary Medicine, 930 Campus Road, 14853, Ithaca, NY, USA. Electronic address:

This report describes transient trifascicular block in three cats presented with lethargy and inappetence, and elevated cardiac troponin I concentrations. The electrocardiogram (ECG) of cat 1 showed a sinus rhythm with pronounced first-degree atrioventricular (AV) block, right bundle branch block, and left anterior fascicular block. The ECG of cat 2 showed truncular left bundle branch block alternating with left anterior fascicular block coupled with prolonged PR intervals, second-degree heart block, and paroxysmal third-degree AV block. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S17602734173020
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http://dx.doi.org/10.1016/j.jvc.2018.02.002DOI Listing
June 2018
6 Reads

Beer, hyponatraemia and cardiac conduction defects.

BMJ Case Rep 2018 Mar 14;2018. Epub 2018 Mar 14.

Department of Medicine, Mater Dei Hospital, Msida, Malta.

The authors report a case of a 68-year-old man who was diagnosed with an irreversible second-degree atrioventricular (AV) Mobitz II 2:1 block temporally associated with profound hyponatraemia. The cause of the hyponatraemia was beer potomania. The co-occurrence of reversible first, second and third-degree heart blocks and hyponatraemia has been described in a few published case reports. Read More

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http://dx.doi.org/10.1136/bcr-2018-224260DOI Listing
March 2018
4 Reads

[Lacosamide associated with high-degree block in a patient with trigeminal neuralgia].

Rev Neurol 2018 Mar;66(6):189-192

Hospital Clinico Universitario Lozano Blesa, 50009 Zaragoza, Espana.

Introduction: Lacosamide is an antiepileptic drug whose exact mechanism of action remains unknown. It acts by increasing the slow inactivation of the voltage-dependent sodium channels of the cell membranes. It is indicated in the treatment of focal seizures with or without secondary generalisation and is occasionally used as adjunct treatment in neuropathic pain. Read More

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March 2018
4 Reads

The electrocardiographic manifestations of athlete's heart and their association with exercise exposure.

Eur J Sport Sci 2018 May 12;18(4):587-593. Epub 2018 Mar 12.

a Department of Cardiology and Centre for Sports and Exercise Medicine , University of Groningen, University Medical Centre Groningen , Netherlands.

Objective: The aim of this study was to define the minimum amount of exercise per week ('current exposure') and the total amount of exercise ('lifetime exposure') needed to lead to the electrocardiographic changes fitting athlete's heart.

Methods: All the pre-participation screenings (including electrocardiograms (ECGs)) from collegiate athletes performed at University Sports Medical Center in 2013 and 2014 were collected. Data on height, weight, sex, age, current sport(s) participation and lifetime sport(s) participation were collected. Read More

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http://dx.doi.org/10.1080/17461391.2018.1441910DOI Listing
May 2018
5 Reads

Maternal steroid therapy for fetuses with second-degree immune-mediated congenital atrioventricular block: a systematic review and meta-analysis.

Acta Obstet Gynecol Scand 2018 Jul 18;97(7):787-794. Epub 2018 Apr 18.

Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Sidney Kimmel Medical College of Thomas Jefferson University, Philadelphia, PA, USA.

Introduction: The aim of this study was to explore the effect of maternal fluorinated steroid therapy on fetuses affected by second-degree immune-mediated congenital atrioventricular block.

Material And Methods: Studies reporting the outcome of fetuses with second-degree immune-mediated congenital atrioventricular block diagnosed on prenatal ultrasound and treated with fluorinated steroids compared with those not treated were included. The primary outcome was the overall progression of congenital atrioventricular block to either continuous or intermittent third-degree congenital atrioventricular block at birth. Read More

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http://dx.doi.org/10.1111/aogs.13338DOI Listing
July 2018
14 Reads
1.990 Impact Factor

Case presentation: implantation of cardiac resynchronization therapy pacemaker via the coronary sinus in a patient with triple valve replacement.

BMC Cardiovasc Disord 2018 02 21;18(1):37. Epub 2018 Feb 21.

Department of Cardiology, Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, 109 Xueyuan Road, Wenzhou, Zhejiang, 325000, China.

Background: In patients with triple valve replacement developing third-degree atrioventricular block (AVB), the most appropriate approach for permanent pacemaker implantation remains questionable.

Case Presentation: In this case presentation, we first described the approach of implantation of the cardiac resynchronization therapy pacemaker (CRT-P) via one bipolar pacing lead in middle cardiac vein (MCV) and one quadripolar pacing lead in anterior interventricular vein (AIV) in a patient developing complete AVB, who had been previously diagnosed with rheumatic valvular heart disease with triple valve replaced. After the CRT-P implantation, the two pacing leads in coronary sinus (CS) provided a dual-site ventricular pacing from the anterior septum and posterior septum, which resulted in a narrow QRS complex and an increased ventricular synchrony. Read More

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https://bmccardiovascdisord.biomedcentral.com/articles/10.11
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http://dx.doi.org/10.1186/s12872-018-0775-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5822565PMC
February 2018
13 Reads

Variation in cardiac markers and electrocardiographic alterations in young calves naturally infected with bovine tropical theileriosis.

Trop Anim Health Prod 2018 Aug 17;50(6):1227-1230. Epub 2018 Feb 17.

College of Veterinary Science and Animal Husbandry, U.P. Pandit Deen Dayal Upadhyaya Pashu Chikitsa Vigyan Vishwavidyalaya Evam Go Anusandhan Sansthan (DUVASU), Mathura, 281001, India.

The present study was designed to assess the deleterious effects of bovine tropical theileriosis on the cardiovascular system and the consequent myocardial involvement in young calves. Myocardial effects in parasitic diseases are often neglected. Hemolytic anemia, associated secondary hypoxia, and vasculitis are cardinal features of bovine theileriosis. Read More

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http://dx.doi.org/10.1007/s11250-018-1548-0DOI Listing
August 2018
1 Read
0.820 Impact Factor

Marked First-Degree Atrioventricular Block and Pseudo-Pacemaker Syndrome in a Pediatric Patient.

Pediatr Cardiol 2018 Mar 12;39(3):637-639. Epub 2018 Feb 12.

Division of Pediatric Cardiology, Children's Hospital of Pittsburgh of UPMC, One Children's Hospital Drive, 4401 Penn Avenue, Pittsburgh, PA, 15224, USA.

We describe a 17-year-old female who presented with 3 weeks of abdominal pain, exercise intolerance, and an episode of altered mental status found to have marked first-degree atrioventricular block. Exercise stress test and cardiac catheterization demonstrated pseudo-pacemaker syndrome, and a permanent pacemaker was placed. Following placement, she has resolution of symptoms and markedly improved exercise tolerance. Read More

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http://dx.doi.org/10.1007/s00246-018-1829-4DOI Listing
March 2018
4 Reads

Pregabalin-induced first degree atrioventricular block in a young patient treated for pain from extrapulmonary tuberculosis.

Monaldi Arch Chest Dis 2017 Sep 28;87(3):838. Epub 2017 Sep 28.

Federico II University School of Medicine.

Pregabalin, widely used in the treatment of several pain disorders, is usually well tolerated. Uncommonly, the drug may induce cardiac side effects, rarely prolongation of the PR interval. The latter has never been described in patients with healthy heart or normal renal function. Read More

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http://monaldi-archives.org/index.php/macd/article/view/838
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http://dx.doi.org/10.4081/monaldi.2017.838DOI Listing
September 2017
15 Reads

A case of cardiac sarcoidosis mimicking cardiac amyloidosis on cardiovascular magnetic resonance.

ESC Heart Fail 2018 04 5;5(2):306-310. Epub 2018 Feb 5.

Department of Cardiology and Nuclear Medicine, National Center for Global Health and Medicine, Tokyo, Japan.

A 52-year-old male visited our hospital with abnormal electrocardiogram and exertional fatigue. The electrocardiogram showed first-degree atrioventricular block, complete right bundle branch block, and inverted T waves in Leads II, III, aVF, V3, and V4. Echocardiography showed biventricular wall thickening involving granular sparkling of the interventricular septum. Read More

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http://doi.wiley.com/10.1002/ehf2.12263
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http://dx.doi.org/10.1002/ehf2.12263DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880662PMC
April 2018
9 Reads

Development and Validation of a New Scoring System to Predict Survival in Patients With Myotonic Dystrophy Type 1.

JAMA Neurol 2018 May;75(5):573-581

Cardiology Department, Cochin Hospital, Filière Neuromusculaire, Paris-Descartes University, Sorbonne Paris Cité University, Assistance Publique-Hôpitaux de Paris, Paris, France.

Importance: Life expectancy is greatly shortened in patients presenting with myotonic dystrophy type 1 (DM1), the most common neuromuscular disease. A reliable prediction of survival in patients with DM1 is critically important to plan personalized health supervision.

Objective: To develop and validate a prognostic score to predict 10-year survival in patients with DM1. Read More

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http://dx.doi.org/10.1001/jamaneurol.2017.4778DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5885178PMC
May 2018
40 Reads

The analysis of the parameters of 24-hr ECG Holter monitoring in patients with blood neoplasms undergoing high-dose chemotherapy and stem cell transplantation.

Ann Noninvasive Electrocardiol 2018 Jul 24;23(4):e12534. Epub 2018 Jan 24.

Department of Internal Medicine, Occupational Diseases and Hypertension, Wroclaw Medical University, Wroclaw, Poland.

Background: Hematopoietic stem cell transplantation (HSCT) is a widely used procedure in the treatment of malignant diseases, including blood neoplasms and has increased survival in hematological diseases. The aim of the study was to analyze parameters of 24-hr ECG monitoring in patients with selected blood neoplasms in whom the procedure of hematopoietic stem cell transplantation was performed.

Methods: The study group consisted of 64 adults diagnosed with hematologic cancer qualified for HSCT with the previous high dose chemotherapy (HDC). Read More

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http://doi.wiley.com/10.1111/anec.12534
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http://dx.doi.org/10.1111/anec.12534DOI Listing
July 2018
9 Reads

Efficacy and Safety of Subcutaneous Neostigmine for Ileus, Acute Colonic Pseudo-obstruction, or Refractory Constipation.

Ann Pharmacother 2018 Jun 23;52(6):505-512. Epub 2018 Jan 23.

1 Duke University Hospital, Durham, NC, USA.

Background: Neostigmine is traditionally administered intravenously for treatment of acute colonic pseudo-obstruction (ACPO), though use is associated with administration constraints and adverse effects.

Objective: To evaluate whether an alternative route of administration for neostigmine via subcutaneous (SQ) delivery is safe and effective in a broad cohort of medical and surgical patients.

Methods: This multicenter, retrospective observational study included adult patients administered SQ neostigmine for ileus, ACPO, or refractory constipation. Read More

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http://dx.doi.org/10.1177/1060028018754302DOI Listing
June 2018
7 Reads

Impaired Recovery of Left Ventricular Function in Patients With Cardiomyopathy and Left Bundle Branch Block.

J Am Coll Cardiol 2018 Jan;71(3):306-317

Division of Cardiology, Department of Medicine, Duke University, Durham, North Carolina; Duke Clinical Research Institute, Duke University, Durham, North Carolina. Electronic address:

Background: Patients with left bundle branch block (LBBB) often respond to cardiac resynchronization therapy (CRT) with left ventricular ejection fraction (LVEF) improvement. Guideline-directed medical therapy (GDMT), not CRT, is first-line therapy for patients with reduced LVEF with LBBB. However, there are little data on how patients with reduced LVEF and LBBB respond to GDMT. Read More

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http://dx.doi.org/10.1016/j.jacc.2017.11.020DOI Listing
January 2018
3 Reads

Hypothermia and severe first-degree heart block.

Cleve Clin J Med 2018 Jan;85(1):10-11

Department of Internal Medicine, Albert Einstein Medical Center, Philadelphia, PA, USA.

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http://dx.doi.org/10.3949/ccjm.85a.17003DOI Listing
January 2018
3 Reads

Lyme carditis with isolated left bundle branch block and myocarditis successfully treated with oral doxycycline.

IDCases 2018 16;11:48-50. Epub 2017 Dec 16.

Infectious Disease Division Winthrop-University Hospital Mineola, New York, United States.

Lyme disease may present with a variety of cardiac manifestations ranging from first degree to third degree heart block. Cardiac involvement with Lyme disease may be asymptomatic, or symptomatic. Atrioventrical conduction abnormalities are the most common manifestation of Lyme carditis. Read More

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http://dx.doi.org/10.1016/j.idcr.2017.12.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760251PMC
December 2017
5 Reads

Experience of Asian males communicating cardiac genetic risk within the family.

J Community Genet 2018 Jul 8;9(3):293-303. Epub 2018 Jan 8.

Cardiovascular Research Institute, National University Health System, 1E Kent Ridge Road, NUHS Tower Block, Level 9, Singapore, Singapore.

The genetic nature of an inherited cardiac condition (ICC) places first- and second-degree relatives at risk of cardiac complications and sudden death, even in the absence of symptoms. Communication of cardiac genetic risk information allows at-risk relatives to clarify, manage, and potentially prevent ICC-associated risks through cardiac screening. Literature regarding family communication of genetic risk information are predominantly based on Western populations, with limited insight into the Asian experience. Read More

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http://dx.doi.org/10.1007/s12687-017-0352-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002304PMC
July 2018
3 Reads

Electrocardiographic patterns and long-term training-induced time changes in 2484 elite football players.

Arch Cardiovasc Dis 2018 May 21;111(5):380-388. Epub 2017 Dec 21.

Service de cardiologie, institut Lorrain du cœur et des vaisseaux Louis-Mathieu, centre hospitalier universitaire de Nancy, 4, rue du Morvan, 54500 Vandœuvre-lès-Nancy, France.

Background: High-level physical training induces cardiac structural and functional changes, including 12-lead electrocardiogram modifications.

Objectives: The purpose of this cross-sectional longitudinal study was to establish a quantitative electrocardiographic profile in highly trained football players. Initial and serial annual electrocardiogram monitoring over subsequent years allowed us to investigate the long-term effects of exercise on cardiac conduction and electrophysiological remodelling. Read More

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http://dx.doi.org/10.1016/j.acvd.2017.10.005DOI Listing
May 2018
19 Reads

Severe cardiac toxicity following alcohol intake in a patient using therapeutic dose of propafenone.

Turk Kardiyol Dern Ars 2017 Dec;45(8):752-754

Department of Cardiology, Kartal Koşuyolu Yüksek İhtisas Training and Research Hospital, İstanbul, Turkey.

An unconscious, 25-year-old, male patient was brought to the emergency department. The patient's electrocardiography demonstrated a wide QRS interval and first-degree atrioventricular block. He was being treated with propafenone twice daily (450 mg) for paroxysmal atrial fibrillation. Read More

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http://dx.doi.org/10.5543/tkda.2017.84553DOI Listing
December 2017
8 Reads

Symptomatic first-degree atrioventricular block in a young woman after taking a fat burner supplement.

Int J Health Sci (Qassim) 2017 Nov-Dec;11(5):79-80

Department of Cardiology, Homerton University Hospital Homerton Row, London E9 6SR, UK.

A 22-year-old woman collapsed at home and was brought to the accident and emergency department. History revealed that she was fit and taken T5 capsule the night before the collapse. There was no history of similar collapses or seizure. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678045PMC
November 2017
6 Reads

Cardiac involvement in myotonic dystrophy: The role of troponins and N-terminal pro B-type natriuretic peptide.

Atherosclerosis 2017 Dec 21;267:110-115. Epub 2017 Oct 21.

Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Via Massarenti 9, 40138 Bologna, Italy. Electronic address:

Background And Aims: Myotonic dystrophy type 1 (DM1) and type 2 (DM2) are dominant inherited muscular dystrophies with multiple systemic involvement, often producing cardiac injury. This study sought to determine the clinical significance of elevated high sensitivity cardiac troponin T and I (hs-cTnT and hs-cTnI), and N-terminal pro B-type natriuretic peptide (NT-pro-BNP) in this population.

Methods: Sixty DM patients (35 men and 25 women; mean age: 45. Read More

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http://dx.doi.org/10.1016/j.atherosclerosis.2017.10.020DOI Listing
December 2017
17 Reads

The Bridge Occlusion Balloon as a safety net in a high-risk transvenous lead extraction procedure.

Interact Cardiovasc Thorac Surg 2018 02;26(2):360-361

Department of Cardiovascular Surgery, University Heart Center Hamburg, Hamburg, Germany.

Injuries to the superior vena cava (SVC) during transvenous lead extraction (TLE) procedures are a rare but life-threatening complication. The Bridge Occlusion Balloon (BOB) is specifically designed for temporary SVC occlusion in TLE procedures. We report the first case of a 27-year-old man using the BOB as a safety net in a high-risk TLE procedure. Read More

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http://dx.doi.org/10.1093/icvts/ivx296DOI Listing
February 2018
11 Reads