11,978 results match your criteria Headache Children


Hydrocephalus-induced neurogenic stunned myocardium and cardiac arrest in a child: completely reversed with CSF diversion.

J Neurosurg Pediatr 2019 Apr 19:1-6. Epub 2019 Apr 19.

Neurogenic stunned myocardium (NSM) is a potentially fatal cause of sudden cardiogenic dysfunction due to an acute neurological event, most commonly aneurysmal subarachnoid hemorrhage in adults. Only two pediatric cases of hydrocephalus-induced NSM have been reported. Here the authors report a third case in a 14-year-old boy who presented with severe headache, decreased level of consciousness, and shock in the context of acute hydrocephalus secondary to fourth ventricular outlet obstruction 3 years after standard-risk medulloblastoma treatment. Read More

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http://dx.doi.org/10.3171/2019.2.PEDS18711DOI Listing

Relaxation training for management of paediatric headache: A rapid review.

Paediatr Child Health 2019 May 7;24(2):103-114. Epub 2019 Feb 7.

Department of Pediatrics, Faculty of Medicine & Dentistry, University of Alberta, Edmonton, Alberta.

The objective of this review was to assess the evidence on relaxation training for management of paediatric headaches. Our methodology was a rapid review of English-language peer reviewed published literature focused on studies evaluating relaxation training as a primary or adjunct management option for headache in a paediatric population (0 to 18 years of age). Seven studies involving 571 children were included in the review. Read More

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https://academic.oup.com/pch/article/24/2/103/5308619
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http://dx.doi.org/10.1093/pch/pxy157DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462122PMC
May 2019
1 Read

Characteristics of children and adolescents at the Switzerland-wide first ambulatory interdisciplinary pain clinic at the University Children's Hospital Basel - a retrospective study.

Swiss Med Wkly 2019 Apr 17;149:w20073. Epub 2019 Apr 17.

Pain Therapy Unit, Department for Anaesthesia, Surgical Intensive Care, Prehospital Emergency Medicine and Pain Therapy, University Hospital Basel, Switzerland.

Aims Of The Study: Given the long history of underestimating chronic pain in children and adolescents, we lack valid data on its assessment and treatment. The psychological and economic burden for patients, their families and society is substantial. The aim of this study was to assess patient characteristics of the first ambulatory interdisciplinary clinic for children and adolescents with chronic pain in Switzerland and compare them with data from other international centres. Read More

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http://dx.doi.org/10.4414/smw.2019.20073DOI Listing

Clinical predictors of symptom resolution for children and adolescents with sport-related concussion.

J Neurosurg Pediatr 2019 Apr 16:1-8. Epub 2019 Apr 16.

1Sports Medicine Center and.

OBJECTIVEThe goal of this study was to determine which variables assessed during an initial clinical evaluation for concussion are independently associated with time until symptom resolution among pediatric patients.METHODSData collected from a prospective clinical registry of pediatric patients with concussion were analyzed. The primary outcome variable was time from injury until symptom resolution. Read More

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http://dx.doi.org/10.3171/2018.11.PEDS18626DOI Listing
April 2019
1 Read

Optimal management after paediatric lumbar puncture: a randomized controlled trial.

BMC Neurol 2019 Apr 13;19(1):64. Epub 2019 Apr 13.

Department of Infectious Diseases, Beijing Children's Hospital, Capital Medical University, Nalishi Road 56#, Xicheng District, Beijing, 100045, China.

Background: To evaluate whether a shorter time of lying supine without a pillow and fasting for solids and liquids (LSFSL) after a lumbar puncture (LP) is associated with a higher risk of post-lumbar puncture headache (PLPH) and post-lumbar puncture lower back pain (PLPBP) in a randomized, assessor-blinded, controlled trial.

Methods: Paediatric patients who underwent their first LP after hospital admission were randomly allocated to either the group with half an hour of LSFSL (0.5 h LSFSL) or 4 h of LSFSL (4 h LSFSL) immediately after LP. Read More

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http://dx.doi.org/10.1186/s12883-019-1275-9DOI Listing
April 2019
1 Read
2.040 Impact Factor

[Headache in children: treatment of the crisis or preventive].

Rev Prat 2019 Feb;69(2):e46

Service de neuropédiatrie, hôpital Salengro, CHRU, 59037 Lille Cedex, France.

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February 2019
2 Reads

[Acute and chronic headache in children].

Rev Prat 2019 Feb;69(2):e39-e45

Service de neuropédiatrie, hôpital Salengro, CHRU, 59037 Lille Cedex, France.

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February 2019

Tolosa-Hunt Syndrome: Clinical Manifestations in Children.

Pediatr Neurol 2019 Feb 20. Epub 2019 Feb 20.

Pediatric Department, University Hospital Of Heraklion, Medical School, University of Crete, Heraklion, Crete, Greece. Electronic address:

Background: Tolosa-Hunt syndrome (THS) is a rare condition in children characterized by painful ophthalmoplegia caused by inflammation of unknown etiology in the cavernous sinus, superior orbital fissure, or orbital apex. Our main purpose was to report two pediatric cases of THS, a typical one and another extremely rare one preceded by facial palsy.

Methods: Both cases were diagnosed with THS based on the 2013 International Classification of Headache Disorders (ICHD-3 beta) criteria. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S08878994183072
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http://dx.doi.org/10.1016/j.pediatrneurol.2019.02.013DOI Listing
February 2019
5 Reads

Cyclic vomiting syndrome and benign paroxysmal torticollis are associated with a high risk of developing primary headache: A longitudinal study.

Cephalalgia 2019 Apr 13:333102419844542. Epub 2019 Apr 13.

1 Headache Center, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.

Background And Aim: Episodic syndromes that may be associated with migraine are a group of disorders affecting patients with migraine or with an increased risk of presenting it, and likely represent an early life expression of migraine. Cyclic vomiting syndrome and benign paroxysmal torticollis are well characterized and represent a frequent cause of request for specialist consultations. The aim of this study is to longitudinally assess the rate of headache in patients presenting with cyclic vomiting syndrome and benign paroxysmal torticollis during infancy, and to define the main clinical features of the disorder. Read More

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http://dx.doi.org/10.1177/0333102419844542DOI Listing
April 2019
2 Reads

Atypical Case of Rosai-Dorfman Disease of the Lacrimal Gland with Adjacent Bone Erosion.

Ocul Oncol Pathol 2019 Feb 18;5(2):128-134. Epub 2018 Jul 18.

Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts, USA.

Background/aims: Rosai-Dorfman disease (RDD) is a rare, self-limited disorder of unknown etiology that affects children and young adults worldwide and typically manifests as chronic, painless cervical lymphadenopathy. Orbital involvement is very rare and may be an isolated extranodal manifestation or associated with concurrent systemic disease. Adjacent bone involvement is most exceptional, and secondary optic neuropathy has never been reported. Read More

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http://dx.doi.org/10.1159/000489127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422131PMC
February 2019

Age- and sex-specific first health care use for migraine in 2016 in children and adolescents from prospectively collected health insurance data in Germany.

Cephalalgia 2019 Apr 11:333102419844543. Epub 2019 Apr 11.

2 Department of Neurology, Ludwig-Maximilians-University Munich, Munich, Germany.

Background: Migraine in children and adolescents is associated with significant disability and a high risk of persistence into adulthood.

Objective: Data on migraine incidence in children and adolescents are few and relatively coarse. To tailor interventions starting shortly after disease onset, detailed information on age- and sex-specific incidence of migraine in children and adolescents is needed. Read More

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http://dx.doi.org/10.1177/0333102419844543DOI Listing
April 2019
1 Read

New Daily Persistent Headache? Comment on "Pediatric Headache and Sleep Disturbance: A Comparison of Diagnostic Groups".

Authors:
Carlo Cianchetti

Headache 2019 Apr;59(4):619-620

Child and Adolescent NeuroPsychiatry, University of Cagliari, Cagliari, Italy.

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https://onlinelibrary.wiley.com/doi/abs/10.1111/head.13509
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http://dx.doi.org/10.1111/head.13509DOI Listing
April 2019
2 Reads

The Mystery of "Red Ear Syndrome": Sign or Syndrome.

Headache 2019 Apr;59(4):624-625

Department of Experimental Biomedicine and Clinical Neurosciences, University of Palermo, Palermo, Italy.

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http://dx.doi.org/10.1111/head.13524DOI Listing

Efficacy of China-made praziquantel for treatment of Schistosomiasis haematobium in Africa: A randomized controlled trial.

PLoS Negl Trop Dis 2019 Apr 10;13(4):e0007238. Epub 2019 Apr 10.

Jiangsu Institute of Parasitic Diseases, Wuxi, Jiangsu, China.

Background: In the roadmap on the neglected tropical diseases (NTD) the World Health Organization (WHO) aims at attaining at least 75% coverage of preventive chemotherapy in pre-school and school-age children by 2020. A randomized controlled trial was used to compare the effectiveness of praziquantel in treating Schistosoma haematobium in Africa using two different sources for the drug, Merck Limited Partnership (KgaA), Germany and Nanjing Pharmaceutical Factory (NPF), China.

Methods: More than 6,000 participants testing positive for S. Read More

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http://dx.plos.org/10.1371/journal.pntd.0007238
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http://dx.doi.org/10.1371/journal.pntd.0007238DOI Listing
April 2019
2 Reads

Discrepancies between self-reported tick bites and evidence of tick-borne disease exposure among nomadic Mongolian herders.

Zoonoses Public Health 2019 Apr 10. Epub 2019 Apr 10.

Division of Infectious Disease, Duke Global Health Institute, Duke University, Durham, North Carolina.

Twenty-six per cent of Mongolians live pastoral lifestyles, increasing their likelihood of exposure to ticks and placing them at a higher risk for contracting tick-borne diseases (TBDs). Anaplasma spp. and Rickettsia spp. Read More

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http://dx.doi.org/10.1111/zph.12579DOI Listing
April 2019
1 Read

ALPK1 missense pathogenic variant in five families leads to ROSAH syndrome, an ocular multisystem autosomal dominant disorder.

Genet Med 2019 Apr 10. Epub 2019 Apr 10.

Department of Ophthalmology and Visual Sciences, John A Moran Eye Center, University of Utah School of Medicine, Salt Lake City, UT, USA.

Purpose: To identify the molecular cause in five unrelated families with a distinct autosomal dominant ocular systemic disorder we called ROSAH syndrome due to clinical features of retinal dystrophy, optic nerve edema, splenomegaly, anhidrosis, and migraine headache.

Methods: Independent discovery exome and genome sequencing in families 1, 2, and 3, and confirmation in families 4 and 5. Expression of wild-type messenger RNA and protein in human and mouse tissues and cell lines. Read More

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http://www.nature.com/articles/s41436-019-0476-3
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http://dx.doi.org/10.1038/s41436-019-0476-3DOI Listing
April 2019
4 Reads
7.329 Impact Factor

Spectrum of the neurologic manifestations in childhood-onset cryopyrin-associated periodic syndrome.

Eur J Paediatr Neurol 2019 Mar 28. Epub 2019 Mar 28.

Department of Pediatric Neurology, Istanbul University-Cerrahpasa, Cerrahpasa Medical School, Istanbul, Turkey.

Objective: Neurologic complications of chronic infantile neurologic, cutaneous and articular syndrome (CINCA) are well-known, whereas there are scarce data regarding neurologic features of milder cryopyrin-associated periodic syndrome (CAPS) phenotypes. We aimed to review the neurologic features in detail and summarize the other CAPS-related manifestations in 12 children.

Methods: All children with CAPS that have been followed-up from pediatric rheumatology outpatient clinic, were enrolled to the study. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10903798183056
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http://dx.doi.org/10.1016/j.ejpn.2019.03.006DOI Listing
March 2019
2 Reads

Efficacy and safety of Levetiracetam as adjunctive treatment in children with focal onset seizures: A systematic review and meta-analysis.

Epilepsy Res 2019 Apr 3;153:40-48. Epub 2019 Apr 3.

College of Pharmacy, Jinan University, Guangzhou, 510632, China; Institute of Dongguan-Jinan University, Dongguan, 523808, China; International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE), Jinan University, Guangzhou, 510632, China. Electronic address:

Objective: To assess the efficacy and safety of levetiracetam (LEV) as adjunctive treatment in children (0-18 years) with focal-onset seizures (FOS) with a larger dataset.

Methods: A pooled analysis would be performed for prospective clinical trials and a meta-analysis for controlled studies. Retrospectives studies were also summarized using descriptive statistics. Read More

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http://dx.doi.org/10.1016/j.eplepsyres.2019.04.001DOI Listing
April 2019
1 Read

The role of obesity and vitamin D deficiency in primary headaches in childhood.

Acta Neurol Belg 2019 Apr 8. Epub 2019 Apr 8.

Division of Neonatology, Abant İzzet Baysal University, 14030, Bolu, Turkey.

This study evaluates the role of obesity, overweight and vitamin D deficiency in primary headaches in childhood. This retrospective observational study included pediatric patients aged 5-17 years admitted to the pediatric neurology clinic with headaches between January 2015 and August 2018 and diagnosed with primary headache based on ICHD III-beta criteria. The control group consisted of healthy children without headache admitted to the pediatric outpatient clinic for check-ups before engaging in athletic or school activities. Read More

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http://dx.doi.org/10.1007/s13760-019-01134-2DOI Listing

Primary headaches during lifespan.

J Headache Pain 2019 Apr 8;20(1):35. Epub 2019 Apr 8.

Headache Research, Wolfson CARD, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.

Primary headaches are one of the most prevalent neurological disorders and can occur during a wide range of lifespan. Primary headaches, especially migraine, are cyclic disorders with a complex sequence of symptoms within every headache attack. There is no systematic review of whether these symptoms changes during lifespan. Read More

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http://dx.doi.org/10.1186/s10194-019-0985-0DOI Listing
April 2019
3 Reads

Craniocervical Arterial Dissection in Children: Pathophysiology and Management.

Pediatr Neurol 2019 Feb 2. Epub 2019 Feb 2.

Section of Pediatric Neurology, Department of Pediatrics and Child Health, University of Manitoba, Manitoba, Canada; Children's Hospital Research Institute of Manitoba, Winnipeg, Manitoba, Canada. Electronic address:

Background: Craniocervical arterial dissection is a commonly reported arteriopathy associated with stroke in children. It is characterized by a high stroke recurrence rate and variable outcomes. Here we review the pathophysiology, clinical presentation, and diagnostic neuroimaging approaches that are helpful in accurate diagnosis and follow-up of children with arterial dissection. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S08878994183130
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http://dx.doi.org/10.1016/j.pediatrneurol.2019.01.020DOI Listing
February 2019
3 Reads

Low Usage of Analgesics for Pediatric Concussion-Related Pain in US Emergency Departments Between 2007 and 2015.

J Pediatr 2019 Apr 4. Epub 2019 Apr 4.

Department of Pediatrics, Division of Pediatric Emergency Medicine, Montreal Children's Hospital, McGill University Health Centre, Montreal, Quebec, Canada. Electronic address:

Objective: To estimate the proportion of pediatric patients with a concussion who received analgesia when presenting with pain to US emergency departments, and to describe the analgesics used.

Study Design: This was a repeated cross-sectional analysis study using the National Hospital Ambulatory Medical Care Survey database of nationally representative emergency department visits from 2007 to 2015. We included children under 18 years old with isolated concussions. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00223476193026
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http://dx.doi.org/10.1016/j.jpeds.2019.02.035DOI Listing
April 2019
2 Reads

Guidelines of the International Headache Society for controlled trials of preventive treatment of migraine in children and adolescents, 1st edition.

Cephalalgia 2019 Apr 4:333102419842188. Epub 2019 Apr 4.

4 Headache Science Center, IRCCS C. Mondino Foundation, Pavia, Italy.

Background: Because the results of clinical trials of investigational treatments influence regulatory policy, prescribing patterns, and use in clinical practice, high quality trials are an essential component of the evidence base for migraine. The International Headache Society has published guidelines for clinical trials in adults with migraine since 1991. With multiple issues specific to children and adolescents with migraine, as well as the emergence of novel trial designs and advances in pharmaceuticals, biologics, devices, and behavioural interventions, there is a need for guidance focusing on issues specific to the conduct of clinical trials in children and adolescents with migraine. Read More

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http://dx.doi.org/10.1177/0333102419842188DOI Listing
April 2019
3 Reads

Two cases of neuroangiostrongyliasis: A rare disease because rarely considered or rarely diagnosed?

J Paediatr Child Health 2019 Apr 3. Epub 2019 Apr 3.

Faculty of Medicine, University of Queensland, Brisbane, Queensland, Australia.

Aim: The rat lungworm, Angiostrongylus cantonensis, is well established in eastern Australia, where it is the almost exclusive cause of human eosinophilic meningoencephalitis (EME). While neuroangiostrongyliasis can result in severe morbidity or death, its diagnosis requires a high index of clinical suspicion among medical practitioners. Prevention requires a high level of public awareness. Read More

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http://dx.doi.org/10.1111/jpc.14461DOI Listing
April 2019
1 Read

Elbasvir/Grazoprevir in People With Hepatitis C Genotype 1 Infection and Child-Pugh Class B Cirrhosis: The C-SALT Study.

Clin Transl Gastroenterol 2019 Mar 28. Epub 2019 Mar 28.

Department of Infectious Disease, Merck & Co., Inc., Kenilworth, New Jersey, USA.

Introduction: Treatment options are limited for people infected with hepatitis C virus (HCV) with decompensated liver disease. The C-SALT study assessed elbasvir (EBR) plus grazoprevir (GZR) in individuals with HCV genotype 1 infection and Child-Pugh class B (CP-B) cirrhosis.

Methods: In this 12-week, phase 2, nonrandomized, open-label study (NCT02115321; Protocol MK-5172-059), participants with CP-B cirrhosis received EBR 50 mg plus GZR 50 mg once daily, and a control group of noncirrhotic participants received EBR 50 mg plus GZR 100 mg once daily. Read More

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http://dx.doi.org/10.14309/ctg.0000000000000007DOI Listing
March 2019
2 Reads

Psychological therapies (remotely delivered) for the management of chronic and recurrent pain in children and adolescents.

Cochrane Database Syst Rev 2019 Apr 2;4:CD011118. Epub 2019 Apr 2.

Cochrane Pain, Palliative and Supportive Care Group, Pain Research Unit, Churchill Hospital, Oxford, UK.

Background: This is the first update of a review published in 2015, Issue 1. Chronic pain is common during childhood and adolescence and is associated with negative outcomes, such as increased severity of pain, reduced function, and low mood. Psychological therapies, traditionally delivered face-to-face with a therapist, are efficacious at reducing pain intensity and disability. Read More

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http://dx.doi.org/10.1002/14651858.CD011118.pub3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445568PMC
April 2019
4 Reads

[Clinical analysis of cerebral venous sinus thrombosis in six children].

Zhonghua Er Ke Za Zhi 2019 Apr;57(4):277-280

Department of Pediatrics, First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.

To summarize the clinical features of cerebral venous sinus thrombosis (CVST) in 6 children, and to improve the understanding of CVST in children. The risk factors, clinical presentations, laboratory findings, imaging manifestations, treatments and outcomes of 6 children (3 males, 3 females) with CVST admitted to the Department of Pediatrics, First Affiliated Hospital of Zhengzhou University from January 2012 to December 2017 were analyzed retrospectively. The risk factors of disease were found in 5 cases, including 3 cases of infection, 1 case of L-asparaginase and dexamethasone chemotherapy and 1 case of oral prednisone alone. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0578-1310.2019.04.009DOI Listing
April 2019
1 Read

Pediatric vs. Adult Prodrome and Postdrome: A Window on Migraine Pathophysiology?

Front Neurol 2019 8;10:199. Epub 2019 Mar 8.

Division of Pediatric Neurology, Department of Pediatrics, Lille Faculty of Medicine and Children's Hospital, Lille, France.

Few studies have been conducted on the prodromal and postdromal phases of the migraine attack in children and adolescents. Using a questionnaire, we found that 67% of 103 children and adolescents with migraine reported at least one prodromal symptom, with a mean number per subject of 1.8 (median 2. Read More

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http://dx.doi.org/10.3389/fneur.2019.00199DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423905PMC
March 2019
4 Reads

Indications and Imaging Modality of Choice in Pediatric Headache.

Neuroimaging Clin N Am 2019 May;29(2):271-289

Department of Radiology, Harvard Medical School, Boston Children's Hospital, 300 Longwood Avenue, Boston, MA 02130, USA.

Pediatric headache is a common problem, with various underlying causes. Appropriate patient selection for neuroimaging is necessary to optimize the clinical evaluation. This review aims to provide a focused discussion of the clinical evaluation of children with headache, including published guidelines pertaining to neuroimaging, technical considerations for neuroimaging, and tailoring of examinations for specific clinical entities known to cause pediatric headache. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10525149193000
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http://dx.doi.org/10.1016/j.nic.2019.01.007DOI Listing
May 2019
3 Reads

Contemporary management of essential thrombocythemia in children.

Expert Rev Hematol 2019 Mar 29. Epub 2019 Mar 29.

b Department of Women's and Children's Health, Pediatric Hemato-Oncology , University of Padova , Padova , Italy.

Introduction: Essential thrombocythemia (ET) is a disease which is extremely rare in children. Only recently, data on pediatric ET have become available Areas covered: In children with sustained platelet count over 450 x 10/L, secondary thrombocytosis must be ruled out. ET workup comprehends research of JAK2V617F, CALR and MPL mutations and bone marrow biopsy (BM). Read More

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https://www.tandfonline.com/doi/full/10.1080/17474086.2019.1
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http://dx.doi.org/10.1080/17474086.2019.1602034DOI Listing
March 2019
18 Reads

A Phase II Double-Blind, Placebo-Controlled, Efficacy and Safety Study of SPN-812 (Extended-Release Viloxazine) in Children With ADHD.

J Atten Disord 2019 Mar 29:1087054719836159. Epub 2019 Mar 29.

6 Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Objective: The objective of this study is to evaluate efficacy and safety of SPN-812 (extended-release viloxazine) for ADHD in children aged 6 to 12 years.

Method: In an 8-week study, 222 participants were randomized to placebo or SPN-812 100, 200, 300, or 400 mg/day. Measurements included ADHD Rating Scale (RS)-IV total score and Clinical Global Impression-Severity (CGI-S) and Clinical Global Impression-Improvement (CGI-I) scores. Read More

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http://dx.doi.org/10.1177/1087054719836159DOI Listing
March 2019
1 Read

Safety and Pharmacokinetics of Glecaprevir/Pibrentasvir in Adults With Chronic Genotype 1-6 Hepatitis C Virus Infections and Compensated Liver Disease.

Clin Infect Dis 2019 Mar 28. Epub 2019 Mar 28.

AbbVie Inc., North Chicago, Illinois.

Background: Untreated, chronic hepatitis C virus (HCV) infection may lead to progressive liver damage, which can be mitigated by successful treatment. This integrated analysis reports the safety, efficacy, and pharmacokinetics (PK) of the ribavirin-free, direct-acting, antiviral, fixed-dose combination of glecaprevir/pibrentasvir (G/P) in patients with chronic HCV genotype 1-6 infections and compensated liver disease, including patients with chronic kidney disease stages 4 or 5 (CKD 4/5).

Methods: Data from 9 Phase II and III clinical trials, assessing the efficacy and safety of G/P treatment for 8-16 weeks, were included. Read More

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http://dx.doi.org/10.1093/cid/ciz022DOI Listing
March 2019
4 Reads

Headache in Postoperative Isolated Sagittal Synostosis.

Plast Reconstr Surg 2019 Apr;143(4):798e-805e

Rotterdam, The Netherlands From the Department of Plastic and Reconstructive Surgery and Hand Surgery and Department of Neurosurgery, Dutch Craniofacial Centre, Erasmus University Medical Center.

Background: This study investigates the relationship between headache and the occurrence of signs associated with intracranial hypertension such as ophthalmic signs, restricted skull growth, and a vertex bulge in children who were operated on for sagittal synostosis.

Methods: A total of 94 patients (aged 6 to 18 years) with sagittal synostosis were asked to indicate their headache frequency. Based on their age at referral, the patients had undergone either frontobiparietal remodeling or an extended strip craniotomy. Read More

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http://dx.doi.org/10.1097/PRS.0000000000005481DOI Listing

Neuroimaging of Pediatric Arteriopathies.

J Neuroimaging 2019 Mar 28. Epub 2019 Mar 28.

Department of Radiology, SUNY Upstate Medical University, Syracuse, NY.

Pediatric arteriopathies are increasingly recognized in school-aged children with a variety of presenting symptoms ranging from headache, seizures, encephalopathy, and neuropsychiatric symptoms as well as focal neurologic deficits due to acute ischemic strokes. However, unlike the adult stroke population, there are differences in the clinical manifestations, the stroke mechanism, and risk factors in pediatric ischemic stroke. There has been increasing awareness and recognition of pediatric cerebral arteriopathies as a predominant stroke etiology. Read More

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http://dx.doi.org/10.1111/jon.12614DOI Listing

Familial hemiplegic migraine in a child with seizure disorder: clinical history is the key to diagnosis.

BMJ Case Rep 2019 Mar 25;12(3). Epub 2019 Mar 25.

Department of Paediatrics, Manipal Melaka Medical College, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India.

Headache is a common presenting complaint in the paediatric population, with often migraine being a clinical diagnosis. Hemiplegic migraine is characterised by aura, sudden onset weakness of one side of the body which usually recovers without any residual neurological deficit. We report a child with a history of seizure disorder, well controlled and off medication for 3 years, who presented with a headache, aura and transient hemiplegia. Read More

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http://dx.doi.org/10.1136/bcr-2018-228687DOI Listing
March 2019
1 Read

Clinical Characteristics of Saffold Virus Infection in Children.

Pediatr Infect Dis J 2019 Mar 21. Epub 2019 Mar 21.

Department of Pediatrics, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan.

Background: Saffold virus (SAFV) is a novel human cardiovirus that was identified in 2007. Recently, SAFV has been isolated from nasal and stool specimens of infants presenting with respiratory and gastrointestinal symptoms and from cerebrospinal fluid (CSF) specimens of children with central nervous system infection. However, little is known regarding clinical characteristics of SAFV in children. Read More

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http://dx.doi.org/10.1097/INF.0000000000002298DOI Listing
March 2019
12 Reads

[Clinical features of children with acute disseminated encephalomyelitis and related recurrence factors].

Zhongguo Dang Dai Er Ke Za Zhi 2019 Mar;21(3):223-228

Department of Neurology, Children's Hospital of Chongqing Medical University/Ministry of Education Key Laboratory of Child Development and Disorders/China International Science and Technology Cooperation Base of Child Development and Critical Disorders/Chongqing Key Laboratory of Pediatrics, Chongqing 400014, China.

Objective: To study the clinical features of children with acute disseminated encephalomyelitis (ADEM) and related recurrence factors.

Methods: A retrospective analysis was performed for the clinical data and prognosis of 73 children with ADEM who were hospitalized from November 2011 to January 2017.

Results: Among the 73 children, 41 (56%) had a history of infection before onset and 7 (10%) had a history of vaccination. Read More

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March 2019
1 Read

Primary intracranial malignant ectomesenchymoma in an adult: Report of a rare case and review of the literature.

Neuropathology 2019 Mar 25. Epub 2019 Mar 25.

Department of Pathology, All India Institute of Medical Sciences, New Delhi, India.

Malignant ectomesenchymoma (MEM) is an exceedingly rare rapidly progressing tumor of soft tissues of the central nervous system, believed to be derived from neural crest cells. The majority of cases have been observed in young children or adolescents. So far only 11 patients with intracranial manifestations (with confirmed clinicopathological data) have been documented. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/neup.12547
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http://dx.doi.org/10.1111/neup.12547DOI Listing
March 2019
3 Reads

The absence of fundus abnormalities in Stargardt disease.

Graefes Arch Clin Exp Ophthalmol 2019 Mar 22. Epub 2019 Mar 22.

Department of Ophthalmology (400), Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands.

Purpose: To raise awareness of Stargardt disease (STGD1) patients without fundus abnormalities.

Methods: Medical records were evaluated for age at onset, initial symptoms and diagnosis, reason for delay of diagnosis, age at STGD1 diagnosis, best-corrected visual acuity (BCVA), ophthalmoscopy, fundus photography, fundus autofluorescence (FAF), fluorescein angiography (FA), spectral-domain optical coherence tomography (SD-OCT), full-field electroretinography (ffERG), color vision test, and the presence of ABCA4 variants.

Results: In 11. Read More

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http://link.springer.com/10.1007/s00417-019-04280-8
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http://dx.doi.org/10.1007/s00417-019-04280-8DOI Listing
March 2019
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Prevalence and association of pain experiences, medication literacy, and use of medication among children and adolescents in Taiwan.

J Pediatr Nurs 2019 Mar 18. Epub 2019 Mar 18.

National Taiwan University Hospital, Taiwan.

Objective: This study assessed the prevalence of children's and adolescents' pain experiences and use of medicine and examined the relationships between pain experiences, medication knowledge, literacy, and use of medicine.

Method: A probability-proportionate-to-size sampling method was used to systematically draw a random sample of schools. In 2014, a national representative sample of 2309 students from 35 primary schools (5th-6th grade), 2700 students from 30 middle schools, and 2013 students from 20 high schools completed the online survey. Read More

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http://dx.doi.org/10.1016/j.pedn.2019.03.002DOI Listing
March 2019
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Rhinologic manifestations of Burkitt Lymphoma in a pediatric population: Case series and systematic review.

Int J Pediatr Otorhinolaryngol 2019 Mar 13;121:127-136. Epub 2019 Mar 13.

Department of Otolaryngology - Head and Neck Surgery, McGill University, Montreal, Canada. Electronic address:

Introduction: Burkitt lymphoma (BL), an aggressive form of B-cell non-Hodgkin's lymphoma, arising from the nose and paranasal sinuses is relatively rare. It can present with various symptoms leading to potential misdiagnosis and delayed treatment. BL is fatal if left untreated, while early identification and treatment can improve prognosis. Read More

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http://dx.doi.org/10.1016/j.ijporl.2019.03.013DOI Listing
March 2019
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The impact of parental attitudes toward children with primary headaches.

Clin Child Psychol Psychiatry 2019 Mar 21:1359104519838571. Epub 2019 Mar 21.

2 Department of Neurology, Cerrahpasa School of Medicine, Istanbul University, Turkey.

There is a lack of data on parental attitudes toward children with primary headaches. The aim of this study is to determine whether there is a relationship between primary headaches and parental attitudes in the pre-adolescent pediatric population. In this cross-sectional study, 195 children with primary headache and 43 healthy children aged 9-16 years were included. Read More

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http://dx.doi.org/10.1177/1359104519838571DOI Listing
March 2019
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Characteristics and predictors of 7- and 30-day hospital readmissions to pediatric neurology.

Neurology 2019 Apr 20;92(16):e1926-e1932. Epub 2019 Mar 20.

From the Division of Child Neurology (A.H., Y.S., S. Karkare, S. Kothare), Department of Pediatrics, Cohen Children's Medical Center, New Hyde Park, NY; and Department of Pediatrics (K.S.), University of Massachusetts Medical School, Worcester.

Objective: Hospital readmission is an important quality improvement measure that has not been well-studied in pediatric neurology. We examined predictors of 7-day and 30-day readmissions for pediatric patients hospitalized with a neurologic diagnosis.

Methods: This was a retrospective study of hospital readmission rates in pediatric neurology patients admitted to a tertiary children's hospital from January 2017 to December 2017. Read More

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http://dx.doi.org/10.1212/WNL.0000000000007280DOI Listing
April 2019
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Comparative Study of Dental Pain Between Children With and Without a History of Maltreatment.

J Oral Facial Pain Headache 2019 Mar 20. Epub 2019 Mar 20.

Aims: To assess the presence of dental pain in child abuse victims and to compare the findings to children in the same age group with no history of abuse in a Southern Brazilian city.

Methods: This cross-sectional comparative study was carried out in a convenience sample of 68 child abuse victims from a center for psychologic support and in a comparative group of 204 students from public and private schools, all aged between 8 and 12 years. Data for socioeconomic and demographic variables were collected, and information regarding dental pain in the last 6 months was obtained via interviews with the children. Read More

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http://dx.doi.org/10.11607/ofph.2291DOI Listing

Neurological Complications associated with Pediatric Liver Transplant in Namazi Hospital: One-Year Follow-Up.

Int J Organ Transplant Med 2019 1;10(1):30-35. Epub 2019 Feb 1.

Department of Pediatrics, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.

Background: 13%-43% of liver transplant (LT) recipients experience severe neurologic events with increased morbidity and mortality.

Objective: To evaluate the incidence of neurological complications after LT in pediatric patients in Namazi Hospital.

Methods: The medical records of 101 children aged between 1 and 18 years who underwent LT between May 2016 and May 2017 at Namazi Hospital were reviewed. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416997PMC
February 2019
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Features of Primary Chronic Headache in Children and Adolescents and Validity of Ichd 3 Criteria.

Front Neurol 2019 15;10:92. Epub 2019 Feb 15.

Headache Center, Department of Neuroscience, Bambino Gesù Children Hospital, Rome, Italy.

Chronic headaches are not a rare condition in children and adolescents with negative effects on their quality of life. Our aims were to investigate the clinical features of chronic headache and usefulness of the International Classification of Headache Disorders 3rd edition (ICHD 3) criteria for the diagnosis in a cohort of pediatric patients. We retrospectively reviewed the charts of patients attending the Headache Center of Bambino Gesù Children and Insubria University Hospital during the 2010-2016 time interval. Read More

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http://dx.doi.org/10.3389/fneur.2019.00092DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413701PMC
February 2019

Case Series of Adolescents With Stroke-Like Symptoms Following Head Trauma.

J Emerg Med 2019 Mar 16. Epub 2019 Mar 16.

McGovern Medical School at the University of Texas Health Science Center at Houston, Houston, Texas.

Background: Studies cite the incidence of pediatric blunt cerebrovascular injuries (BCVI) ranges from 0.03% to 1.3%. Read More

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http://dx.doi.org/10.1016/j.jemermed.2019.01.029DOI Listing
March 2019
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Occipital Neuralgia and Cervicogenic Headache: Diagnosis and Management.

Curr Neurol Neurosci Rep 2019 Mar 19;19(5):20. Epub 2019 Mar 19.

Women's College Hospital Centre for Headache, Division of Neurology, University of Toronto, Toronto, Canada.

Purpose Of Review: Occipital neuralgia (ON) and cervicogenic headache (CGH) are secondary headache disorders with occipital pain as a key feature. Due to significant phenotypic overlap, differentiating ON and CGH from primary headache disorders such as migraine or tension-type headache, or other secondary headache disorders, can be clinically challenging. This article reviews the anatomy, clinical features, unique diagnostic considerations, and management approaches relating to ON and CGH. Read More

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http://dx.doi.org/10.1007/s11910-019-0937-8DOI Listing
March 2019
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Gliomatosis Cerebri Among Children and Adolescents: An Individual-Patient Data Meta-analysis of 182 Patients.

J Child Neurol 2019 Mar 19:883073819836551. Epub 2019 Mar 19.

1 Department of Hygiene, Epidemiology and Medical Statistics, Medical School, National and Kapodistrian University of Athens, Athens, Greece.

Background:: Gliomatosis cerebri is a rare but fatal widespread infiltrating central nervous system tumor. We aimed to describe diagnostic and prognostic features of gliomatosis cerebri among children and adolescents.

Methods:: We conducted a systematic literature review for published case reports and case series on patients with histologically confirmed gliomatosis cerebri and extracted data on an individual patient level for those aged 0-18 years. Read More

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http://dx.doi.org/10.1177/0883073819836551DOI Listing
March 2019
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The prevalence of headache in German pupils of different ages and school types.

Cephalalgia 2019 Mar 18:333102419837156. Epub 2019 Mar 18.

1 Pain Center, University Hospital and Faculty of Medicine Carl Gustav Carus, TU Dresden, Dresden, Germany.

Background/objective: Headache in pupils is underestimated and has a negative impact on learning and life. The aim of this study was to investigate headache prevalence and its collateral effects, in pupils of different ages and school types in a German city.

Methods: Anonymized questionnaires were distributed to 5419 pupils attending primary and secondary schools. Read More

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http://dx.doi.org/10.1177/0333102419837156DOI Listing
March 2019
2 Reads