83,218 results match your criteria Headache Care: education research and management for the practising clinician [Journal]


What are the research priorities for idiopathic intracranial hypertension? A priority setting partnership between patients and healthcare professionals.

BMJ Open 2019 Mar 15;9(3):e026573. Epub 2019 Mar 15.

Department of Metabolic Neurology, University of Birmingham, Birmingham, UK.

Objective: Idiopathic intracranial hypertension (IIH) is under-researched and the aim was to determine the top 10 research priorities for this disease.

Design: A modified nominal group technique was used to engage participants who had experience of IIH.

Setting: This James Lind Alliance Priority Setting Partnership was commissioned by IIH UK, a charity. Read More

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http://dx.doi.org/10.1136/bmjopen-2018-026573DOI Listing

Ventriculostomy and endoscopic biopsy of pineal mass with hydrocephalus and unexpected definitive diagnosis.

Neurocirugia (Astur) 2019 Mar 13. Epub 2019 Mar 13.

Servicio de Neurocirugía, Complejo Hospitalario de Jaén, Hospital Neurotraumatológico, Jaén, España.

A 72-year-old female with no relevant medical history consulted in the emergency room for a two-week history of headache, vomiting and gait disturbance. Head CT scan revealed obstructive hydrocephalus secondary to a pineal mass with compression of the third ventricle. Magnetic Resonance showed another mass located in the right Lushcka foramen. Read More

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http://dx.doi.org/10.1016/j.neucir.2019.01.005DOI Listing

A Retrospective, Epidemiological Review of Hemiplegic Migraines in a Military Population.

Mil Med 2019 Mar 16. Epub 2019 Mar 16.

University of Texas at San Antonio, One UTSA Circle, San Antonio, TX.

Introduction: Headaches are one of the world's most common disabling conditions. They are also both highly prevalent and debilitating among military personnel and can have a significant impact on fitness for duty. Hemiplegic migraines are an uncommon, yet severely incapacitating, subtype of migraine with aura for which there has been a significant increase amongst US military personnel over the past decade. Read More

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http://dx.doi.org/10.1093/milmed/usz040DOI Listing

Response of migraine without aura to kudzu.

Neurol Sci 2019 Mar 16. Epub 2019 Mar 16.

Neurology Departmet, Casa di Cura del Policlinico - Igea Headache Center, Via Marcona 69, Milan, Italy.

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http://dx.doi.org/10.1007/s10072-019-03798-3DOI Listing

Headache attributed to IIH: clinical evolution in IHS criteria through the years.

Neurol Sci 2019 Mar 16. Epub 2019 Mar 16.

Casa di Cura del Policlinico, Igea Headache Center, Via Marcona, 69, Milan, Italy.

Idiopathic intracranial hypertension (IIH) is a condition characterized by increased intracranial pressure without a detectable cause. The most common symptom of IIH is a headache, which occurs in almost all cases at the time of diagnosis with various headache phenotypes. In clinical practice, diagnosis of headache attributed to IIH is given referring to the International Headache Society (IHS) criteria of the International Classification of Headache Disorders. Read More

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http://dx.doi.org/10.1007/s10072-019-03795-6DOI Listing

Anatomic considerations in headaches associated with cervical sagittal imbalance: A cadaveric biomechanical study.

J Clin Neurosci 2019 Mar 12. Epub 2019 Mar 12.

Edward Hines Jr. VA Hospital, Hines, IL, USA; Loyola University Medical Center Dept. of Orthopaedic Surgery, Maywood, IL, USA. Electronic address:

Chronic Forward Head Posture is associated with headaches, neck pain, and disability, though few studies have investigated the effects it has on the suboccipital triangle. The objective of this study was to quantitatively assess whether the biomechanical changes in the suboccipital triangle help explain the clinical manifestations of Forward Head Posture. Specifically, this study aimed to identify whether the Greater Occipital Nerve or C2 nerve root may be compressed in Forward Head Posture. Read More

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http://dx.doi.org/10.1016/j.jocn.2019.02.003DOI Listing

A rare cause of postpartum acute hyponatremia.

Endocrinol Diabetes Metab Case Rep 2019 Mar 15;2019. Epub 2019 Mar 15.

Department of Internal Medicine F, Soroka University Medical Center, Beer Sheva, Israel.

A previously healthy 24-year-old female underwent an emergent caesarean section without a major bleeding described. During the first post-operative days (POD) she complained of fatigue, headache and a failure to lactate with no specific and conclusive findings on head CT. On the following days, fever rose with a suspicion of an obstetric surgery-related infection, again with no evidence to support the diagnosis. Read More

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http://dx.doi.org/10.1530/EDM-18-0124DOI Listing

CGRP Antagonists for the Treatment of Chronic Migraines: a Comprehensive Review.

Curr Pain Headache Rep 2019 Mar 14;23(5):29. Epub 2019 Mar 14.

Valley Anesthesiology and Pain Consultants, Phoenix, AZ, USA.

Purpose Of Review: The purpose of the following review is to summarize the most recent understanding of migraine pathophysiology, as well as of basic and clinical science pharmacologic literature regarding the development of calcitonin gene receptor peptide (CGRP) antagonists as a novel therapeutic modality for the treatment of migraine headaches. A review is provided of erenumab, the first of its class FDA approved CGRP antagonist.

Recent Findings: Despite its high prevalence, the occurrence and treatment of migraine headaches is poorly understood. Read More

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http://dx.doi.org/10.1007/s11916-019-0768-yDOI Listing

The Hypertensive Headache: a Review.

Curr Pain Headache Rep 2019 Mar 14;23(5):30. Epub 2019 Mar 14.

Mayo Clinic Arizona, 13400 E Shea Blvd, Scottsdale, AZ, 85259, USA.

Purpose Of Review: The purpose of this review is to provide an overview and update on the common causes of headache attributed to arterial hypertension with a focus on secondary headache disorders. We will also highlight uncommon and recent findings in this area of research.

Recent Findings: There is some controversy in the relationship between chronic hypertension and headache, particularly migraine; recent research suggests that there may be a link, but it is likely complex and multifactorial. Read More

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http://link.springer.com/10.1007/s11916-019-0767-z
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http://dx.doi.org/10.1007/s11916-019-0767-zDOI Listing
March 2019
1 Read

[Memory and attention deficit in migraine: overlooked symptoms].

Zh Nevrol Psikhiatr Im S S Korsakova 2019 ;119(2):39-43

Sechenov First Moscow State Medical University, Moscow, Russia.

Aim: To evaluate the prevalence of objective cognitive impairment (CI) in patients with episodic migraine (EM) during the interictal period and in the chronic migraine (CM) population.

Material And Methods: Sixty-four patients with CM and 42 patients with low-frequency EM (less than 4 headache days a month), aged 18-59, were enrolled. Depression and anxiety were assessed with the Hospital Anxiety and Depression Scale (HADS). Read More

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http://dx.doi.org/10.17116/jnevro201911902139DOI Listing
January 2019

Soy Isoflavone Extract Does Not Increase the Intoxicating Effects of Acute Alcohol Ingestion in Human Volunteers.

Front Pharmacol 2019 27;10:131. Epub 2019 Feb 27.

Department of Psychiatry and Legal Medicine and Department of Pharmacology, Therapeutics and Toxicoloy, Universitat Autònoma de Barcelona, Cerdanyola del Vallés, Spain.

Soy beans contain isoflavones, including daidzein and genistein, with biological activities related to therapeutic effects in reducing osteoporosis, decreasing adverse menopausal manifestations, providing protection from cardiovascular diseases, and reducing hormone-dependent cancers and age-related cognitive-decline. Daidzein has been described as inhibiting the aldehyde-dehydrogenase-2 enzyme (ALDH2), and reducing alcohol use in clinical pilot studies. Our aim was to evaluate the possible interactions between a soy extract product and alcohol in a crossover, single blind, randomized study. Read More

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http://dx.doi.org/10.3389/fphar.2019.00131DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400998PMC
February 2019

Efficacy, immunogenicity and safety of a recombinant tetravalent dengue vaccine (CYD-TDV) in children aged 2-17 years: systematic review and meta-analysis.

BMJ Open 2019 Mar 13;9(3):e019368. Epub 2019 Mar 13.

Instituto de Estudos em Saúde Coletiva, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.

Background: Randomised controlled trials have evaluated the recombinant tetravalent dengue vaccine (CYD-TDV). However, individual results may have little power to identify differences among the populations studied.

Objective: To evaluate efficacy, immunogenicity and safety of CYD-TDV in the prevention of dengue in children aged 2-17 years. Read More

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http://dx.doi.org/10.1136/bmjopen-2017-019368DOI Listing

Tip of the iceberg in idiopathic intracranial hypertension.

Pract Neurol 2019 Apr;19(2):178-179

Metabolic Neurology, Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK

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http://dx.doi.org/10.1136/practneurol-2019-002198DOI Listing

Entirely suprasellar Rathke cleft cysts: clinical features and surgical efficacy of endoscopic endonasal transtuberculum sellae approach.

World Neurosurg 2019 Mar 11. Epub 2019 Mar 11.

Department of Neurosurgery, Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan.

Introduction: Rathke cleft cysts (RCCs) arise from the remnant of the Rathke pouch and are usually found in the intermediate lobe. In most cases, RCCs remain intrasellar and extended into the suprasellar region. Rarely, they emerge entirely into the suprasellar cistern. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.03.011DOI Listing

Betaine anhydrous in homocystinuria: results from the RoCH registry.

Orphanet J Rare Dis 2019 Mar 14;14(1):66. Epub 2019 Mar 14.

CHRU de Tours, Service de Médecine Interne, Université François Rabelais, Tours, France.

Background: The Registry of Adult and Paediatric Patients Treated with Cystadane® - Homocystinuria (RoCH) is a non-interventional, observational, multi-centre, post-authorization safety study that aimed to identify safety of betaine anhydrous (Cystadane®) in the treatment of patients with inborn errors of homocysteine metabolism (homocystinuria) in order to minimise the treatment associated risks and establish better knowledge on its clinical use. The registry included patients of all ages with homocystinuria who were treated with betaine anhydrous in conjunction with other therapies. Clinical data were collected retrospectively from 2007 to 2013, then prospectively up to February 2014. Read More

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http://dx.doi.org/10.1186/s13023-019-1036-2DOI Listing

Concurrent infections of dengue virus serotypes in Bali, Indonesia.

BMC Res Notes 2019 Mar 12;12(1):129. Epub 2019 Mar 12.

Eijkman Institute for Molecular Biology, Ministry of Research, Technology, and Higher Education of the Republic of Indonesia, Jl. Diponegoro 69, Jakarta, 10430, Indonesia.

Objective: To describe cases of dengue virus (DENV) concurrent infections in patients from both local and international traveler visiting Bali, Indonesia.

Results: During a hospital-based study, 260 patients (from 161 local and 99 international traveler patients) were recruited. Among them, 190 were positive by DENV RT-PCR in which eight patients (five local and three international travelers) detected as having concurrent infections by two different DENV serotypes. Read More

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http://dx.doi.org/10.1186/s13104-019-4164-9DOI Listing

An observational study of fixed-dose Tanacetum parthenium nutraceutical preparation for prophylaxis of pediatric headache.

Ital J Pediatr 2019 Mar 12;45(1):36. Epub 2019 Mar 12.

Child Neurology, Pediatric Headache & Sleep Disorders Centre, Chair of Pediatrics, NESMOS Department, Faculty of Medicine and Psychology, Sapienza University, Via Di Grottarossa, 1035-1039, 00189, Rome, Italy.

Background: Migraine is one of the most prevalent chronic pain manifestations of childhood. Despite the multitude of available treatments, parents are often concerned about chronic therapies and pediatricians have insufficient confidence in prescribing prophylactic drugs. Therefore, there is now growing interest for natural supplements used to control recurrent migraine headaches. Read More

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http://dx.doi.org/10.1186/s13052-019-0624-zDOI Listing
March 2019
1.236 Impact Factor

Combinations of Symptoms in Emergency Presentations: Prevalence and Outcome.

J Clin Med 2019 Mar 12;8(3). Epub 2019 Mar 12.

Emergency Department, University Hospital Basel, Petersgraben 2, CH-4031 Basel, Switzerland.

The predictive power of certain symptoms, such as dyspnoea, is well known. However, research is limited to the investigation of single chief complaints. This is in contrast to patients in the emergency department (ED) presenting usually more than one symptom. Read More

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http://dx.doi.org/10.3390/jcm8030345DOI Listing

Endogenous Neurostimulation and Physiotherapy in Cluster Headache: A Clinical Case.

Brain Sci 2019 Mar 12;9(3). Epub 2019 Mar 12.

Departamento de Fisioterapia, Centro Superior de Estudios Universitarios La Salle, Universidad Autónoma de Madrid, Madrid 28023, Spain.

Objective: The aim of this paper is to describe the progressive changes of chronic cluster headaches (CHs) in a patient who is being treated by a multimodal approach, using pharmacology, neurostimulation and physiotherapy.

Subject: A male patient, 42 years of age was diagnosed with left-sided refractory chronic CH by a neurologist in November 2009. In June 2014, the patient underwent a surgical intervention in which a bilateral occipital nerve neurostimulator was implanted as a treatment for headache. Read More

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http://dx.doi.org/10.3390/brainsci9030060DOI Listing

Influence of Selection Bias in Survey Studies Derived From a Patient-Focused Organization: A Comparison of Response Data From a Single Tertiary Care Center and the Acoustic Neuroma Association.

Otol Neurotol 2019 Apr;40(4):504-510

Department of Otolaryngology - Head and Neck Surgery.

Background: The Acoustic Neuroma Association (ANA) is a national, nonprofit organization, focused on the education and support of patients with vestibular schwannoma (VS). The aim of the present study is to characterize the profile of ANA survey respondents and compare them with non-ANA patients evaluated at a single tertiary academic referral center to investigate the potential influence of selection bias.

Methods: A prospectively maintained VS quality-of-life (QOL) database, comprised of patients evaluated at the authors' center and members of the ANA, was queried. Read More

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http://dx.doi.org/10.1097/MAO.0000000000002151DOI Listing
April 2019
1 Read

Acute neurological adverse events during immune checkpoint inhibition therapy in patients with melanoma brain metastases.

Melanoma Res 2019 Mar 11. Epub 2019 Mar 11.

Departments of Dermatology.

The common adverse effects of immune checkpoint blockade therapy are well recognised. However, neurological adverse effects of checkpoint inhibitor therapy are less widely appreciated, and their clinical management remains challenging. Therefore, we report our experience of managing acute, life-threatening neurological toxicity during immune checkpoint inhibitor therapy. Read More

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http://dx.doi.org/10.1097/CMR.0000000000000597DOI Listing

A clinical analysis on 40 cases of spontaneous intracranial hypotension syndrome.

Somatosens Mot Res 2019 Mar 14:1-7. Epub 2019 Mar 14.

c Department of Neurology , the Affiliated Hospital of Xuzhou Medical University , Xuzhou , China.

Objective: To investigate clinical and imaging features of 40 patients with spontaneous intracranial hypotension (SIH).

Methods: 40 cases of spontaneous intracranial hypotension (SIH) diagnosed in our hospital from June 2013 to September 2017 were collected and retrospectively analyzed.

Results: In our study, the male to female ratio was 2:3. Read More

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http://dx.doi.org/10.1080/08990220.2019.1566122DOI Listing

[Migraine, trigeminal neuralgia and cluster headache].

Authors:
Caroline Roos

Rev Prat 2018 Nov;68(9):e339-e350

Neurologue, responsable du centre d'urgence des céphalées, hôpital Lariboisière, 75010 Paris, France.

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November 2018

Nummular Headache: 2 Cases With Good Beta Blocker Responses and a Narrative Review.

Headache 2019 Mar 14. Epub 2019 Mar 14.

Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.

Objective: To report 2 new nummular headache (NH) cases and review the clinical features and management of NH.

Background: NH is a coin-shaped headache with a fixed shape and size. Since the first case series was reported by Pareja, approximately 300 cases have been reported. Read More

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http://doi.wiley.com/10.1111/head.13503
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http://dx.doi.org/10.1111/head.13503DOI Listing
March 2019
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Efficacy and safety of perampanel in generalized and focal to bilateral tonic-clonic seizures: A comparative study of Asian and non-Asian populations.

Epilepsia 2019 Mar;60 Suppl 1:47-59

Eisai Singapore Pte. Ltd., Singapore.

Perampanel is an approved adjunctive treatment for focal seizures with or without focal to bilateral tonic-clonic (FBTC) seizures and generalized tonic-clonic (GTC) seizures. We compared efficacy and safety of perampanel vs placebo in Asian and non-Asian populations in a post hoc analysis of pooled data from 5 randomized phase 3 studies. Patients (≥12 years old) with focal + FBTC seizures received perampanel 2, 4, 8, or 12 mg or placebo; patients with GTC seizures received perampanel 8 mg or placebo (titration: 4-6 weeks; maintenance: 13 weeks). Read More

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http://dx.doi.org/10.1111/epi.14644DOI Listing

Efficacy, safety, and tolerability of perampanel in Asian and non-Asian patients with epilepsy.

Epilepsia 2019 Mar;60 Suppl 1:37-46

Eisai Singapore Pte. Ltd., Singapore.

People of different ethnic or racial backgrounds may experience variations in pharmacokinetic and pharmacodynamic responses to drug therapies. Our post hoc analysis evaluated the efficacy, safety, and tolerability of perampanel in Asian and non-Asian populations with refractory focal seizures with or without focal to bilateral tonic-clonic (FBTC) seizures. This analysis pooled data from 4 randomized, placebo-controlled, phase-3 studies involving patients aged ≥12 years who have focal seizures with or without FBTC seizures. Read More

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http://doi.wiley.com/10.1111/epi.14642
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http://dx.doi.org/10.1111/epi.14642DOI Listing
March 2019
1 Read

Familial Hemiplegic Migraines and Baseline Neuropsychological Testing: A Case Report.

Headache 2019 Mar 14. Epub 2019 Mar 14.

Brooke Army Medical Center, Fort Sam Houston, TX, USA.

Objective: To explore the neuropsychological correlates and implications of familial hemiplegic migraines (FHMs).

Background: FMH is a rare, autosomal dominant subtype of migraine that only occurs in 0.01% of the population. Read More

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http://dx.doi.org/10.1111/head.13505DOI Listing

Louse-borne relapsing fever (Borrelia recurrentis infection).

Authors:
David A Warrell

Epidemiol Infect 2019 Jan;147:e106

Nuffield Department of Clinical Medicine,University of Oxford,Oxford,UK.

Louse-borne relapsing fever (LBRF) is an epidemic disease with a fascinating history from Hippocrates' times, through the 6th century 'Yellow Plague', to epidemics in Ireland, Scotland and England in the 19th century and two large Afro-Middle Eastern pandemics in the 20th century. An endemic focus persists in Ethiopia and adjacent territories in the Horn of Africa. Since 2015, awareness of LBRF in Europe, as a re-emerging disease, has been increased dramatically by the discovery of this infection in dozens of refugees arriving from Africa. Read More

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http://dx.doi.org/10.1017/S0950268819000116DOI Listing
January 2019

Invited Commentary on Preventive Anti-Migraine Therapy (PAMT).

Curr Treat Options Neurol 2019 Mar 14;21(4):14. Epub 2019 Mar 14.

Thomas Jefferson University, Jefferson Headache Center, 900 Walnut St #200, Philadelphia, PA, 19107, USA.

Migraine is a chronic paroxysmal neurological disorder characterized by multiphase attacks of head pain and a myriad of neurological symptoms. Chronic migraine causes a great personal and societal burden. Many patients are poorly responsive to, or non-compliant with, conventional migraine preventive therapies. Read More

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http://link.springer.com/10.1007/s11940-019-0555-4
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http://dx.doi.org/10.1007/s11940-019-0555-4DOI Listing
March 2019
1 Read

Clinical use of Tc-HMPAO-labeled platelets in cerebral sinus thrombosis imaging.

Acta Neurol Belg 2019 Mar 13. Epub 2019 Mar 13.

Department of Nuclear Medicine, Vali-Asr Hospital, Tehran University of Medical Sciences, Tehran, 1419731351, Iran.

Magnetic resonance imaging (MRI) and computed tomography (CT) are not always conclusive for the detection of cerebral venous sinus thrombosis (CVST). Tc-HMPAO-labeled platelets may be useful in cases with high clinical suspicion. Three patients with headaches with or without intraparenchymal hemorrhage that were highly suspected to have CVST, despite inconclusive anatomical imaging, were selected for inclusion in the study. Read More

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http://dx.doi.org/10.1007/s13760-019-01107-5DOI Listing

Enhanced Recovery for Breast Reconstruction Surgery.

Curr Pain Headache Rep 2019 Mar 14;23(4):27. Epub 2019 Mar 14.

Department of Anesthesiology, LSU Health Science Center, 1542 Tulane Avenue, Suite 659, New Orleans, LA, 70112, USA.

Purpose Of Review: Enhanced recovery pathways are a well-described perioperative healthcare program involving evidence-based interventions. Enhanced recovery is designed to standardize techniques such as drug selection and nerve blocks in order to speed recovery and reduce overall hospital costs.

Recent Findings: A PubMed literature search was performed for articles that included the terms enhanced recovery and breast reconstruction surgery. Read More

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http://dx.doi.org/10.1007/s11916-019-0761-5DOI Listing

When to Consider Prophylactic Antimigraine Therapy in Children with Migraine.

Curr Treat Options Neurol 2019 Mar 14;21(4):15. Epub 2019 Mar 14.

Department of Neurology, Emory Brain Health Center, Atlanta, GA, USA.

Purpose Of Review: Headache is not an uncommon complaint in children, and recognition of migraine is increasing in children and adolescents. Treatment options consist of abortive and preventive medications; however, when to start the preventive treatment is not clear in the pediatric population. This article reviews current guidelines and practices to provide a better clinical approach in the management of migraines in children and adolescents. Read More

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http://link.springer.com/10.1007/s11940-019-0560-7
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http://dx.doi.org/10.1007/s11940-019-0560-7DOI Listing
March 2019
1 Read

Spinal Cord Stimulation: Comparing Traditional Low-frequency Tonic Waveforms to Novel High Frequency and Burst Stimulation for the Treatment of Chronic Low Back Pain.

Curr Pain Headache Rep 2019 Mar 14;23(4):25. Epub 2019 Mar 14.

Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA, 02115, USA.

Purpose Of Review: The purpose of the present investigation is to summarize supporting evidence for novel sub-perception spinal cord stimulation (SCS) therapy over traditional paresthesia inducing low-frequency waveforms for the treatment of chronic pain. The focus of this review is to summarize key studies comparing traditional low-frequency tonic waveforms to modern high frequency and burst stimulation for the treatment of patients with chronic intractable low back pain and/or leg pain.

Recent Findings: Several recent studies have demonstrated the benefit of novel SCS therapies over traditional low-frequency SCS for the treatment of patients with chronic low back and/or leg pain. Read More

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http://dx.doi.org/10.1007/s11916-019-0763-3DOI Listing

Enhanced Recovery Pathways for Cardiac Surgery.

Curr Pain Headache Rep 2019 Mar 14;23(4):28. Epub 2019 Mar 14.

Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Boston, MA, USA.

Purpose Of Review: Enhanced recovery after surgery (ERAS) has become a widespread topic in perioperative medicine over the past 20 years. The goals of ERAS are to improve patient outcomes and perioperative experience, reduce length of hospital stay, minimize complications, and reduce cost. Interventions and factors before, during, and after surgery all potentially play a role with the cumulative effect being superior quality of patient care. Read More

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http://link.springer.com/10.1007/s11916-019-0764-2
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http://dx.doi.org/10.1007/s11916-019-0764-2DOI Listing
March 2019
1 Read

Current Approach to Undifferentiated Headache Management in the Emergency Department.

Curr Pain Headache Rep 2019 Mar 14;23(4):26. Epub 2019 Mar 14.

Department of Emergency Medicine, George Washington University School of Medicine and Health Sciences, 2120 L St., Washington, DC, 20037, USA.

Purpose Of Review: To discuss pharmacological interventions in the emergency department (ED) setting for the management of acute primary headache.

Recent Findings: Acute headache treatment in the ED has seen an expansion in terms of possible pharmacological interventions in recent years. After a thorough evaluation ruling out dangerous causes of headache, providers should take the patient's history, comorbidities, and prior therapy into consideration. Read More

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http://dx.doi.org/10.1007/s11916-019-0765-1DOI Listing

Regional Catheters for Outpatient Surgery-a Comprehensive Review.

Curr Pain Headache Rep 2019 Mar 14;23(4):24. Epub 2019 Mar 14.

Department of Anesthesiology, Louisiana State University Health Science Center, New Orleans, LA, USA.

Purpose Of Review: This review summarizes and discusses the history of continuous catheter blockade (CCB), its current applications, clinical considerations, economic benefits, potential complications, patient education, and best practice techniques.

Recent Findings: Regional catheters for outpatient surgery have greatly impacted acute post-operative pain management and recovery. Prior to development, options for acute pain management were limited to the use of opioid pain medications, NSAIDS, neuropathic agents, and the like as local anesthetic duration of action is limited to 4-8 h. Read More

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http://link.springer.com/10.1007/s11916-019-0762-4
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http://dx.doi.org/10.1007/s11916-019-0762-4DOI Listing
March 2019
1 Read

Acute Hepatitis in Infections Caused by Dengue Virus in Southern Punjab, Pakistan.

Cureus 2018 Dec 28;10(12):e3788. Epub 2018 Dec 28.

Internal Medicine, Quaid-E-Azam Medical College, Bahawalpur, PAK.

Background Dengue is the most common vector-borne disease worldwide. It poses a significant health burden in tropical and subtropical countries. Common clinical presentations include retro-orbital pain, fever, headache, nausea, vomiting and aches and pains in the body. Read More

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http://dx.doi.org/10.7759/cureus.3788DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402748PMC
December 2018

Epidemiology, diagnosis and treatment of moyamoya disease.

Exp Ther Med 2019 Mar 25;17(3):1977-1984. Epub 2019 Jan 25.

Department of Neurosurgery, The First People's Hospital of Jining, Jining, Shandong 272011, P.R. China.

Moyamoya disease (MMD) is a type of chronic cerebrovascular occlusion disease, which frequently occurs in East Asian populations, including pediatric and adult patients, and may lead to ischemic or hemorrhagic stroke, headache, epilepsy or transient ischemic attack. To date, the underlying mechanisms of MMD have remained to be fully elucidated, but certain studies have indicated that genetic factors may be an important component of its development. Cerebral angiography is the best approach for diagnosing MMD. Read More

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http://dx.doi.org/10.3892/etm.2019.7198DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395994PMC
March 2019
1 Read

Chronic persistent Horner's syndrome in trigeminal autonomic cephalalgia subtypes and alleviation with treatment: two case reports.

J Med Case Rep 2019 Mar 14;13(1):60. Epub 2019 Mar 14.

Private Practice Interventional Pain Management, Willow Grove, PA, USA.

Background: The trigeminal autonomic cephalalgias are a group of primary headache syndromes marked by severe head pain and associated cranial autonomic symptoms which can include a full or partial Horner's syndrome. Rarely, the eye-related symptoms will become fixed even between headache attacks. There is minimal documentation that the Horner's syndrome can be reversed if successful treatment of the underlying headache disorder is initiated. Read More

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http://dx.doi.org/10.1186/s13256-019-1986-yDOI Listing

Manual therapy for the pediatric population: a systematic review.

BMC Complement Altern Med 2019 Mar 13;19(1):60. Epub 2019 Mar 13.

Parker University, 2540 Walnut Hill Lane, Dallas, TX, 75229, USA.

Background: This systematic review evaluates the use of manual therapy for clinical conditions in the pediatric population, assesses the methodological quality of the studies found, and synthesizes findings based on health condition. We also assessed the reporting of adverse events within the included studies and compared our conclusions to those of the UK Update report.

Methods: Six databases were searched using the following inclusion criteria: children under the age of 18 years old; treatment using manual therapy; any type of healthcare profession; published between 2001 and March 31, 2018; and English. Read More

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https://bmccomplementalternmed.biomedcentral.com/articles/10
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http://dx.doi.org/10.1186/s12906-019-2447-2DOI Listing
March 2019
1 Read

CGRP and migraine from a cardiovascular point of view: what do we expect from blocking CGRP?

J Headache Pain 2019 Mar 12;20(1):27. Epub 2019 Mar 12.

UOC Neurologia e Stroke Unit, Ospedale SS Filippo e Nicola, Avezzano, Italy.

Calcitonin gene-related peptide (CGRP) is a neuropeptide with a pivotal role in the pathophysiology of migraine. Blockade of CGRP is a new therapeutic target for patients with migraine. CGRP and its receptors are distributed not only in the central and peripheral nervous system but also in the cardiovascular system, both in blood vessels and in the heart. Read More

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http://dx.doi.org/10.1186/s10194-019-0979-yDOI Listing

Genotypic diversity and clinical outcome of cryptococcosis in renal transplant recipients in Brazil.

Emerg Microbes Infect 2019 ;8(1):119-129

b Division of Infectious Disease, Department of Medicine , Duke University School of Medicine , Durham , NC , USA.

Genotypic diversity and fluconazole susceptibility of 82 Cryptococcus neoformans and Cryptococcus gattii isolates from 60 renal transplant recipients in Brazil were characterized. Clinical characteristics of the patients and prognostic factors were analysed. Seventy-two (87. Read More

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http://dx.doi.org/10.1080/22221751.2018.1562849DOI Listing
January 2019

Chikungunya virus in Asia - Pacific: a systematic review.

Emerg Microbes Infect 2019 ;8(1):70-79

a Institute of Health and Biomedical Innovation, School of Biomedical Sciences , Queensland University of Technology , Brisbane , QLD , Australia.

Chikungunya virus (CHIKV) is a mosquito-borne pathogen that causes an acute febrile syndrome and severe, debilitating rheumatic disorders in humans that may persist for months. CHIKV's presence in Asia dates from at least 1954, but its epidemiological profile in the region remains poorly understood. We systematically reviewed CHIKV emergence, epidemiology, clinical features, atypical manifestations and distribution of virus genotypes, in 47 countries from South East Asia (SEA) and the Western Pacific Region (WPR) during the period 1954-2017. Read More

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https://www.tandfonline.com/doi/full/10.1080/22221751.2018.1
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http://dx.doi.org/10.1080/22221751.2018.1559708DOI Listing
January 2019
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Influence of Climate on the Incidence of RCVS - A Retrospective Study From Taiwan.

Headache 2019 Mar 13. Epub 2019 Mar 13.

Faculty of Medicine, National Yang-Ming University School of Medicine, Taipei, Taiwan.

Background: Cold weather is reportedly a precipitator of reversible cerebral vasoconstriction syndrome (RCVS) in a few cases. We systematically investigated whether meteorological factors correlate with the occurrence of RCVS.

Methods: We conducted a retrospective analysis of a cohort of patients diagnosed with RCVS or probable RCVS, based on International Classification of Headache Disorders, third edition (ICHD-3) criteria, in a hospital-based headache center from March 2005 to February 2014. Read More

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http://dx.doi.org/10.1111/head.13504DOI Listing

Single-Dose Pharmacokinetics and Safety of Solriamfetol in Participants With Normal or Impaired Renal Function and With End-Stage Renal Disease Requiring Hemodialysis.

J Clin Pharmacol 2019 Mar 13. Epub 2019 Mar 13.

Orlando Clinical Research Center, Orlando, FL, USA.

Solriamfetol (JZP-110), a selective dopamine and norepinephrine reuptake inhibitor with wake-promoting effects, is renally excreted ∼90% unchanged within 48 hours. Effects of renal impairment and hemodialysis on the pharmacokinetics and safety of 75-mg single-dose solriamfetol were evaluated in adults with normal renal function (n = 6); mild (n = 6), moderate (n = 6), or severe (n = 6) renal impairment; and end-stage renal disease (ESRD) with and without hemodialysis (n = 7). Relative to normal renal function, geometric mean area under the plasma concentration-time curve from time zero to infinity increased 53%, 129%, and 339%, and mean half-life was 1. Read More

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http://dx.doi.org/10.1002/jcph.1402DOI Listing
March 2019
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The unique role of the trigeminal autonomic reflex and its modulation in primary headache disorders.

Curr Opin Neurol 2019 Mar 6. Epub 2019 Mar 6.

Department of Systems Neuroscience, University Medical Center Eppendorf, Hamburg, Germany.

Purpose Of Review: The trigeminal autonomic reflex is a physiological reflex with an important protective function which also plays a role in pathophysiological conditions, such as primary headache. It is not understood whether the autonomic symptoms in trigeminal autonomic cephalalgias and migraine are the consequence of severe trigeminal discharge or indeed directly driven by central generators as part of the pathophysiology, underlying these syndromes.

Recent Findings: Modulating this reflex, and particularly the parasympathetic reflex arc, has been shown to be effective in treating headache. Read More

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http://dx.doi.org/10.1097/WCO.0000000000000691DOI Listing

Clinical Characteristics and Outcome of Children Hospitalized With Scrub Typhus in an Area of Endemicity.

J Pediatric Infect Dis Soc 2019 Mar 13. Epub 2019 Mar 13.

Department of Medicine, Swiss Tropical and Public Health Institute and Faculty of Medicine, University of Basel, Switzerland.

Background: Scrub typhus, caused by Orientia tsutsugamushi, is a major cause of acute febrile illness in children in the rural tropics.

Methods: We recruited 60 febrile pediatric patients with a positive scrub typhus rapid diagnostic test result and 40 healthy controls from Chiang Rai Province in northern Thailand. Diagnosis was confirmed by the detection of (1) O. Read More

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http://dx.doi.org/10.1093/jpids/piz014DOI Listing
March 2019
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Clinical and hormonal characteristics of patients with different types of hypophysitis: a single-center experience.

Arch Endocrinol Metab 2019 Feb;63(1):47-52

Saglik Bilimleri University, Ankara Numune Education and Research Hospital Department of Endocrinology and Metabolism, Ankara, Turkey.

Objective: The inflammation of the pituitary gland is known as hypophysitis. It is a rare disease accounting for approximately 0.24%-0. Read More

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http://dx.doi.org/10.20945/2359-3997000000102DOI Listing
February 2019
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