83,689 results match your criteria Headache: The Journal of Head and Face Pain[Journal]


Arteriopathy Influences Pediatric Ischemic Stroke Presentation, but Sickle Cell Disease Influences Stroke Management.

Stroke 2019 May;50(5):1089-1094

Departments of Pediatrics, Neurology and Neurotherapeutics, University of Texas Southwestern Medical Center at Dallas and Children's Health Dallas (M.M.D.).

Background and Purpose- Sickle cell disease (SCD) and arteriopathy are pediatric stroke risk factors that are not mutually exclusive. The relative contributions of sickled red blood cells and arteriopathy to stroke risk are unknown, resulting in unclear guidelines for primary and secondary stroke prevention when both risk factors are present. We hypothesized that despite similarities in clinical presentation and radiographic appearance of arteriopathies, stroke evaluation and management differ in children with SCD compared with those without SCD. Read More

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https://www.ahajournals.org/doi/10.1161/STROKEAHA.118.022800
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http://dx.doi.org/10.1161/STROKEAHA.118.022800DOI Listing
May 2019
1 Read

N-Methyl-d-aspartate receptor open-channel blockers memantine and magnesium modulate nociceptive trigeminovascular neurotransmission in rats.

Eur J Neurosci 2019 Apr 22. Epub 2019 Apr 22.

Department of Neurology, University of California, San Francisco, San Francisco, CA, USA.

Experimental and clinical studies suggest that the low-affinity N-methyl-d-aspartate (NMDA) receptor open-channel blockers Mg and memantine are effective in reducing trigeminal nociceptive activation. The aim of the present study was to investigate the apparent effectiveness of these channel blockers using a model of trigeminal activation in vivo. Rats were anesthetized before electrically stimulating the dura mater adjacent the middle meningeal artery. Read More

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http://dx.doi.org/10.1111/ejn.14423DOI Listing

Atypical case of posterior reversible encephalopathy syndrome related to late onset postpartum eclampsia: A case report.

Medicine (Baltimore) 2019 Apr;98(16):e15187

Advanced Emergency and Critical Care Medical Center, Okayama University Hospital, Okayama City, Okayama, Japan.

Rationale: Eclampsia, an obstetric emergency frequently seen in pregnant or puerperal women, is a risk factor for posterior reversible encephalopathy syndrome (PRES). Most cases of eclampsia occur postpartum. We report a woman with PRES associated with eclampsia 10 weeks post-delivery, the latest onset ever reported. Read More

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http://dx.doi.org/10.1097/MD.0000000000015187DOI Listing

Psychosocial and Demographic Characteristics of Children and Adolescents With Headache Presenting for Treatment in a Headache Infusion Center.

Headache 2019 Apr 22. Epub 2019 Apr 22.

NeuroDevelopmental Science Center, Akron Children's Hospital, Akron, OH, USA.

Background: Approximately 10% of pediatric patients have recurrent headaches, with migraine being the most common headache type. If untreated, migraine may progress to status migrainosus, a debilitating condition of prolonged duration, high pain severity, and significant disability. There is high variability in the treatment of status migrainosus including medications used and treatment setting, which may occur in the emergency room, as an inpatient admission, or, less often, in an outpatient infusion center. Read More

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http://dx.doi.org/10.1111/head.13537DOI Listing

Cerebral Sinus Venous Thrombosis in the Setting of Acute Mastoiditis.

Cureus 2019 Feb 6;11(2):e4023. Epub 2019 Feb 6.

Internal Medicine, University of Connecticut, Farmington, USA.

Cerebral sinus venous thrombosis (CSVT) is a rare complication of acute mastoiditis with a declining incidence in the post-antibiotic era. In the adult population its incidence ranges from three to four cases per million. Here we present a case of a 47-year-old female with triple negative breast cancer on chemotherapy who underwent a molar tooth extraction, which was followed two weeks later by the sudden onset of left-sided frontotemporal headache radiating down the face, left ear fullness with associated hearing loss, toothache, and left orbital pain. Read More

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https://www.cureus.com/articles/16460-cerebral-sinus-venous-
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http://dx.doi.org/10.7759/cureus.4023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6453619PMC
February 2019
1 Read

Use of atypical antipsychotics and risk of hypertension: A case report and review literature.

SAGE Open Med Case Rep 2019 9;7:2050313X19841825. Epub 2019 Apr 9.

University Center of Votuporanga (UNIFEV), São Paulo, Brazil.

Atypical antipsychotics is being considered in the treatment of "negative" symptoms of psychoses, such as schizophrenia. In this case report, we presented a case of a patient with psychiatric disorder who developed hypertension soon after starting using atypical antipsychotic. A 53-year-old woman had reported having episodes of tachycardia, nausea, headache and high blood pressure. Read More

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http://dx.doi.org/10.1177/2050313X19841825DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6457028PMC

Targeting the Blood-Brain Barrier to Prevent Sepsis-Associated Cognitive Impairment.

J Cent Nerv Syst Dis 2019 9;11:1179573519840652. Epub 2019 Apr 9.

Graduate Programs in Neuroscience, Department of Neuroscience, School of Medicine, Health Sciences Center, West Virginia University, Morgantown, WV, USA.

Sepsis is a systemic inflammatory disease resulting from an infection. This disorder affects 750 000 people annually in the United States and has a 62% rehospitalization rate. Septic symptoms range from typical flu-like symptoms (eg, headache, fever) to a multifactorial syndrome known as sepsis-associated encephalopathy (SAE). Read More

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http://dx.doi.org/10.1177/1179573519840652DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456845PMC

Comments on "Short-lasting, unilateral, neuralgiform headache attacks".

Ann Indian Acad Neurol 2019 Apr-Jun;22(2):249-250

Department of Neurosurgery, St. Olav's Hospital, Trondheim University Hospital, Trondheim, Norway.

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http://dx.doi.org/10.4103/aian.AIAN_353_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472229PMC

[Study on the safety and immunogenicity of simultaneous vaccination on both hepatitis E and hepatitis B vaccines].

Zhonghua Liu Xing Bing Xue Za Zhi 2019 Apr;40(4):451-456

Beijing Chaoyang District Center for Disease Control and Prevention, Beijing 100021, China.

Safety and immunogenicity regarding simultaneous vaccination on both hepatitis E and hepatitis B vaccines were studied. A total of 600 healthy subjects aged 18-60 were recruited in Chaoyang district of Beijing city, from September 2015 to December 2016. Subjects meeting the inclusion and exclusion criteria were randomly divided into 3 groups: the simultaneous vaccination group of hepatitis E and hepatitis B, the hepatitis B vaccination group and the hepatitis E vaccination group. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0254-6450.2019.04.015DOI Listing

Comparing the effects of 3 oxygen delivery methods plus intravenous ketorolac on primary headaches: A randomized clinical trial.

Am J Emerg Med 2019 Apr 13. Epub 2019 Apr 13.

Tehran University of Medical Sciences, Department of Emergency Medicine, Dr. Shariati Hospital, Kargar Ave, P.O Box 14117-13137, Tehran, Iran. Electronic address:

Objective: To compare three different oxygen therapy methods in primary headaches.

Methods: Design: A randomized placebo-controlled clinical trial was conducted between January 2016 and October 2017.

Setting: The emergency department of a university-affiliated urban hospital in Tehran, Iran. Read More

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http://dx.doi.org/10.1016/j.ajem.2019.04.018DOI Listing

Zhixiong Capsule (ZXC), a traditional Chinese patent medicine, prevents atherosclerotic plaque formation in rabbit carotid artery and the related mechanism investigation based on network pharmacology and biological research.

Phytomedicine 2018 Dec 7;59:152776. Epub 2018 Dec 7.

School of Traditional Chinese Material, Shenyang Pharmaceutical University, Shenyang 110016, China. Electronic address:

Background And Aims: Chinese patent medicine Zhixiong Capsule (ZXC) has been used in clinical treatment against blood stasis-induced dizziness and headache for many years in China.

Hypothesis/purpose: Recent clinical observations demonstrated a good efficacy of ZXC against atherosclerotic plaque formation in carotid arteries. The aims of this study were to verify the plaque-preventing efficacy of ZXC in animals and to investigate the underlying mechanisms. Read More

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http://dx.doi.org/10.1016/j.phymed.2018.11.036DOI Listing
December 2018

Safety and Efficacy of 0.5% Carbomer 980 Gel for Treatment of Symptoms of Common Cold: Results of 2 Randomized Trials.

Authors:
Lara Dennie

Drugs R D 2019 Apr 19. Epub 2019 Apr 19.

Clinical Research Innovation, GlaxoSmithKline Consumer Healthcare, 184 Liberty Corner Rd, Warren, NJ, 07059, USA.

Background: Two studies of intranasal 0.5% carbomer 980 gel were conducted evaluating nasal tolerability in healthy volunteers and safety and efficacy in adults with common cold symptoms.

Methods: Study 1 randomly assigned healthy adults to 0. Read More

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http://link.springer.com/10.1007/s40268-019-0270-3
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http://dx.doi.org/10.1007/s40268-019-0270-3DOI Listing

Onset of efficacy and duration of response of galcanezumab for the prevention of episodic migraine: a post-hoc analysis.

J Neurol Neurosurg Psychiatry 2019 Apr 19. Epub 2019 Apr 19.

Eli Lilly and Company, Indianapolis, Indiana, USA.

Background And Objective: As new migraine prevention treatments are developed, the onset of a preventive effect, how long it is maintained and whether patients initially non-responsive develop clinically meaningful responses with continued treatment can be assessed.

Methods: Analyses were conducted post-hoc of a double-blind, placebo-controlled, phase II-a study in patients with episodic migraine receiving galcanezumab 150 mg or placebo biweekly for 12 weeks ( 13:885, 2014). The number of migraine headache days per week, and onset of efficacy measured as the first week galacanezumab separated from placebo were determined. Read More

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http://jnnp.bmj.com/lookup/doi/10.1136/jnnp-2018-320242
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http://dx.doi.org/10.1136/jnnp-2018-320242DOI Listing
April 2019
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Quantitative analysis of medicinal plants used to treat musculoskeletal ailments by non-institutionally trained siddha practitioners of Virudhunagar district, Tamil Nadu, India.

J Ayurveda Integr Med 2019 Apr 16. Epub 2019 Apr 16.

Division of Ethnopharmacology, Entomology Research Institute, Loyola College, Nungambakkam, Chennai, Tamil Nadu, 600 034, India. Electronic address:

Background: Siddha is one of the traditional medical systems of India; previous ethnobotanical survey in Virudhunagar district indicated a high consensus for treating musculoskeletal ailments.

Objectives: This study was aimed to quantitatively document the medicinal plants used to treat musculoskeletal ailments by non-institutionally trained siddha practitioners of Virudhunagar district, Tamil Nadu, India.

Materials And Methods: This work was the outcome of free-list interviews conducted among 45 informants between April 2016 and January 2017. Read More

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http://dx.doi.org/10.1016/j.jaim.2018.11.005DOI Listing

Hydrocephalus-induced neurogenic stunned myocardium and cardiac arrest in a child: completely reversed with CSF diversion.

J Neurosurg Pediatr 2019 Apr 19:1-6. Epub 2019 Apr 19.

Neurogenic stunned myocardium (NSM) is a potentially fatal cause of sudden cardiogenic dysfunction due to an acute neurological event, most commonly aneurysmal subarachnoid hemorrhage in adults. Only two pediatric cases of hydrocephalus-induced NSM have been reported. Here the authors report a third case in a 14-year-old boy who presented with severe headache, decreased level of consciousness, and shock in the context of acute hydrocephalus secondary to fourth ventricular outlet obstruction 3 years after standard-risk medulloblastoma treatment. Read More

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http://dx.doi.org/10.3171/2019.2.PEDS18711DOI Listing

Murine typhus Presenting with Status Epilepticus.

Int J Infect Dis 2019 Apr 16. Epub 2019 Apr 16.

Department of General Medicine, Changi General Hospital, 2 Simei Street 3, 529889 Singapore.

Patients with rickettsial infection usually present with a febrile illness, headache, arthromyalgia and various biochemical abnormalities. Neurologic involvement is rare in murine typhus. Here, we report a case of a patient who presented with status epilepticus secondary to Rickettsia typhi infection. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S12019712193018
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http://dx.doi.org/10.1016/j.ijid.2019.04.012DOI Listing
April 2019
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Efficacy and Safety of High-frequency Repetitive Transcranial Magnetic Stimulation for Post-Stroke Depression:A Systematic Review and Meta-Analysis.

Arch Phys Med Rehabil 2019 Apr 16. Epub 2019 Apr 16.

Department of psychology rehabilitation, the First Affiliated Hospital of the Medical ,College, Shihezi University, Shihezi, Xinjiang, China. Electronic address:

Objective: To summarize and systematically review the efficacy and safety of high frequency repetitive transcranial magnetic stimulation (HF-rTMS) for depression in stroke patients.

Data Sources: Six databases (Wanfang, CNKI, PubMed, Embase, Cochrane Library, and Web of Science) were searched from inception until November 15, 2018.

Study Selection: Seventeen randomized controlled trials were included for meta-analysis. Read More

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http://dx.doi.org/10.1016/j.apmr.2019.03.012DOI Listing

Assessment of the Olfactory Function in Patients With Idiopathic Intracranial Hypertension Using the Sniffin' Sticks Test: A Case-Control Study.

Headache 2019 Apr 18. Epub 2019 Apr 18.

Department of Neurology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.

Objective: Despite the lack of recognition in clinical practice, there is increasing evidence that patients with idiopathic intracranial hypertension may suffer from hyposmia. The current case-control study aims to evaluate olfactory dysfunction in a large series of patients with idiopathic intracranial hypertension.

Methods: All subjects, 44 idiopathic intracranial hypertension patients and 57 healthy controls, underwent olfactory function assessment using standardized "Sniffin' Sticks" test at a tertiary referral center of a university hospital. Read More

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http://dx.doi.org/10.1111/head.13538DOI Listing

A Case of Spontaneous Spinal Subdural Hematoma Complicated by Cranial Subarachnoid Hemorrhage and Spinal Adhesive Arachnoiditis.

Case Rep Orthop 2019 13;2019:7384701. Epub 2019 Mar 13.

Department of Orthopedic Surgery, Toho University, Tokyo, Japan.

A 76-year-old woman with a spinal subdural hematoma (SDH) was presented with severe back pain without headache. Magnetic resonance imaging (MRI) performed 4 days after onset showed SDH extending from Th2 to L3. She was diagnosed with spontaneous SDH without neurological manifestation, and conservative treatment was selected. Read More

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http://dx.doi.org/10.1155/2019/7384701DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436331PMC

Decompression Hemicraniectomy for Refractory Intracranial Hypertension in Reversible Cerebral Vasoconstriction Syndrome.

J Neurosci Rural Pract 2019 Apr-Jun;10(2):355-359

Division of Neurocritical Care, Cerebrovascular Center, Cleveland Clinic Foundation, Cleveland, Ohio, USA.

Reversible cerebral vasoconstriction syndrome (RCVS) is a disorder of dysregulation of cerebrovascular tone resulting in transient segmental vasoconstriction which resolves in 1-3 months. Cerebral edema is an underrecognized complication in RCVS. It is likely multifactorial. Read More

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http://dx.doi.org/10.4103/jnrp.jnrp_334_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454955PMC

Concurrent Venous Stenting of the Transverse and Occipito-Marginal Sinuses: An Analogy with Parallel Hemodynamic Circuits.

J Neurosci Rural Pract 2019 Apr-Jun;10(2):334-338

Department of Neurosurgery, Pennsylvania State University, Hershey, Pennsylvania, USA.

Nonthrombotic intracranial venous occlusive disease (NIVOD) has been implicated in the pathophysiology of idiopathic intracranial hypertension (IIH) and various non-IIH headache syndromes. Endovascular stenting of stenotic, dominant transverse sinuses (TSs) may reduce trans-stenosis pressure gradients, decrease intracranial pressure, and alleviate symptoms in a subset of NIVOD patients. We present a case in which concurrent stenting of the occipito-marginal sinus obliterated the residual trans-stenosis pressure gradient across an initially stented dominant TS. Read More

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http://dx.doi.org/10.4103/jnrp.jnrp_259_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454934PMC

Microsurgical Management for Aneurysm Arising from a Low-Lying Internal Carotid Artery-Posterior Communicating Artery Bifurcation through the Anterior Temporal Approach.

J Neurosci Rural Pract 2019 Apr-Jun;10(2):331-333

Department of Neurosurgery, Iwate Prefectural Chubu Hospital, Kitakami, Iwate, Japan.

A low-lying internal carotid artery (ICA) running closer to the skull base than in usual cases prevents use of the standard transsylvian approach (TSA) to view an aneurysm through the retrocarotid space. A 75-year-old male had a 10-day history of headache and left eyelid ptosis. Initial computed tomography (CT) showed no evidence of subarachnoid hemorrhage. Read More

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http://www.ruralneuropractice.com/text.asp?2019/10/2/331/254
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http://dx.doi.org/10.4103/jnrp.jnrp_274_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454945PMC
April 2019
1 Read

Tuberculosis: A Common Infection with Rare Presentation, Isolated Sellar Tuberculoma with Panhypopituitarism.

J Neurosci Rural Pract 2019 Apr-Jun;10(2):327-330

Department of Neurosurgery, Superspeciality Hospital and Government Medical College, Nagpur, Maharashtra, India.

Isolated sellar tuberculoma is a very rare condition and usually presents with headache and decreased vision. It can present with panhypopituitarism with 3 nerve palsy. Tuberculoma mimics pituitary adenoma clinically as well as radiologically and requires endoscopic transsphenoidal surgery and histopathological examination for the final diagnosis. Read More

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http://www.ruralneuropractice.com/text.asp?2019/10/2/327/254
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http://dx.doi.org/10.4103/jnrp.jnrp_332_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454932PMC
April 2019
1 Read

Etiologic and Clinical Features of Cerebral Venous Sinus Thrombosis in Saudi Arabia.

J Neurosci Rural Pract 2019 Apr-Jun;10(2):278-282

Department of Medicine, Division of Neurology, 7-112L Clinical Sciences Building, University of Alberta, Edmonton, Canada.

Objective: Our study aims to evaluate the etiologic and clinical features of cerebral venous sinus thrombosis (CVST) in Saudi Arabia, and secondarily whether gender plays a role in CVST.

Materials And Methods: Data were collected retrospectively from the stroke registry during the period from January 2008 to April 2018, and the patients with the diagnosis of CVST were identified, and data were analyzed for any gender-specific differences in clinical presentation and etiology of cerebral venous thrombosis.

Results: There were 15 females while 11 males with a female:male ratio of 1. Read More

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http://www.ruralneuropractice.com/text.asp?2019/10/2/278/254
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http://dx.doi.org/10.4103/jnrp.jnrp_305_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454937PMC
April 2019
2 Reads

Changes in MIDAS, Perceived Stress, Frontalis Muscle Activity and Non-Steroidal Anti-Inflammatory Drugs Usage in Patients with Migraine Headache without Aura following Ayurveda and Yoga Compared to Controls: An Open Labeled Non-Randomized Study.

Ann Neurosci 2018 Dec 11;25(4):250-260. Epub 2018 Sep 11.

Division of Yoga and Life Sciences, Swami Vivekananda Yoga Anusandhana Samsthana (S-VYASA) A Deemed to be University, Bengaluru, India.

Background: There has been a significant increase in the use of complementary and integrative medicine to provide long-term healing solutions in migraine headache patients. Knowing the limitations of conventional medical approach, the present study evaluated the influence of two Indian traditional systems of medicine on migraine-related disability, autonomic variables, perceived stress, and muscle activity in patients with migraine headache without aura.

Methods: Thirty subjects recruited to the Ayurveda and Yoga (AY) group underwent traditional (Bio-purification) using therapeutic Purgation followed by yoga therapy, while 30 subjects of control (CT) group continued on symptomatic treatment (non-steroidal anti-inflammatory drugs [NSAID's]) for 90 days. Read More

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http://dx.doi.org/10.1159/000492269DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470355PMC
December 2018
1 Read

Readability, content, quality and accuracy assessment of internet-based patient education materials relating to labor analgesia.

Int J Obstet Anesth 2019 Jan 8. Epub 2019 Jan 8.

Section of Obstetric Anesthesiology, Department of Anesthesiology, Cedars-Sinai Medical Center, USA.

Background: With over 90% of parturients searching the internet for health information, the quality of information is important. Web-based patient education materials (PEMs) related to labor analgesia are frequently of low readability. This study compares the readability, content, quality and accuracy of labor analgesia-related PEMs from relevant healthcare society websites and the top internet search results. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S0959289X183027
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http://dx.doi.org/10.1016/j.ijoa.2019.01.003DOI Listing
January 2019
1 Read

Idiopathic intracranial hypertension presenting with isolated unilateral facial nerve palsy: a case report.

J Med Case Rep 2019 Apr 19;13(1):94. Epub 2019 Apr 19.

Neurology Department, University of Minnesota, Minneapolis, MN, USA.

Background: Idiopathic intracranial hypertension, also known as pseudotumor cerebri, is a disorder characterized by increased intracranial pressure of unclear pathogenesis in the absence of other structural and obstructive lesions that is predominantly, although not exclusively, seen in obese women of childbearing age. Patients with idiopathic intracranial hypertension commonly present with a headache, transient visual obscurations, and intracranial noises with some cranial nerves occasionally involved, most commonly CN VI. We report idiopathic intracranial hypertension presenting with isolated complete unilateral facial nerve palsy, as the sole cranial nerve involved, which is a presentation rarely reported in the literature. Read More

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http://dx.doi.org/10.1186/s13256-019-2060-5DOI Listing

Efficacy and safety of namilumab, a human monoclonal antibody against granulocyte-macrophage colony-stimulating factor (GM-CSF) ligand in patients with rheumatoid arthritis (RA) with either an inadequate response to background methotrexate therapy or an inadequate response or intolerance to an anti-TNF (tumour necrosis factor) biologic therapy: a randomized, controlled trial.

Arthritis Res Ther 2019 Apr 18;21(1):101. Epub 2019 Apr 18.

Takeda Development Centre, London, UK.

Background: Namilumab (AMG203), an immunoglobulin G1 monoclonal antibody that binds with high affinity to granulocyte-macrophage colony-stimulating factor (GM-CSF), was evaluated in a phase II randomized, double-blind, placebo-controlled study to investigate the efficacy and safety in patients with rheumatoid arthritis (RA) with an inadequate response to methotrexate (MTX-IR) or anti-tumour necrosis factor therapy (TNF-IR).

Methods: Subcutaneous namilumab (20, 80, or 150 mg) or placebo was administered at baseline and weeks 2, 6, and 10 in patients on stable background methotrexate therapy who were with MTX-IR or TNF-IR. Primary endpoint was mean change from baseline in the 28-joint Disease Activity Score, C-reactive protein version (DAS28-CRP) at week 12 comparing each of the three doses of namilumab to placebo. Read More

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http://dx.doi.org/10.1186/s13075-019-1879-xDOI Listing

Association between anxiety and aggression in adolescents: a cross-sectional study.

BMC Pediatr 2019 Apr 18;19(1):115. Epub 2019 Apr 18.

College of Pharmacy and Division of Life and Pharmaceutical Sciences, Ewha Womans University, 52 Ewhayeodae-gil, Seodaemun-Gu, Seoul, 03760, South Korea.

Background: The purpose of this study was to investigate the relationship between anxiety proneness and aggressive behavior in adolescents.

Methods: A quantitative, large scale cross-sectional study was conducted in Korea. The survey questionnaire included general health behavior and scales for assessing anxiety (Revised Children's Manifest Anxiety Scale; RCMAS) and aggressive behavior (The Aggression Questionnaire; AQ) in adolescents. Read More

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https://bmcpediatr.biomedcentral.com/articles/10.1186/s12887
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http://dx.doi.org/10.1186/s12887-019-1479-6DOI Listing
April 2019
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The self-reported needs of patients following subarachnoid hemorrhage (SAH).

Disabil Rehabil 2019 Apr 18:1-7. Epub 2019 Apr 18.

b Division of Cardiovascular Sciences , The University of Manchester, Core Technology Facility , Manchester , UK.

Background: Despite advances in the acute care of subarachnoid haemorrhage, longer-term services remain under-developed. Clinical measures are commonly used to assess outcome and quality of life, but patient-reported needs and the extent to which they are met have not been measured. This information is essential to plan and develop evidence-based, patient-centred services. Read More

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http://dx.doi.org/10.1080/09638288.2019.1595748DOI Listing

Meningioma and psychiatric symptoms: An individual patient data analysis.

Asian J Psychiatr 2019 Mar 28;42:94-103. Epub 2019 Mar 28.

Department of Psychiatry, Dr Ram Manohar Lohia Hospital PGIMER, New Delhi, India.

Meningioma is a slow-growing benign tumor arising from meninges and is usually asymptomatic. Though neuropsychiatric symptoms are common in patients with brain tumors, they often can be the only manifestation in cases of meningioma. Meningiomas might present with mood symptoms, psychosis, memory disturbances, personality changes, anxiety, or anorexia nervosa. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S18762018183113
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http://dx.doi.org/10.1016/j.ajp.2019.03.029DOI Listing
March 2019
2 Reads

The diagnostic accuracy of headache measurement instruments: A systematic review and meta-analysis focusing on headaches associated with musculoskeletal symptoms.

Cephalalgia 2019 Apr 18:333102419840777. Epub 2019 Apr 18.

6 University Medical Center Utrecht, Utrecht University, Department of Oral-Maxillofacial Surgery and Special Dental Care, Utrecht, the Netherlands.

Aim: To systematically review the available literature on the diagnostic accuracy of questionnaires and measurement instruments for headaches associated with musculoskeletal symptoms.

Design: Articles were eligible for inclusion when the diagnostic accuracy (sensitivity/specificity) was established for measurement instruments for headaches associated with musculoskeletal symptoms in an adult population. The databases searched were PubMed (1966-2018), Cochrane (1898-2018) and Cinahl (1988-2018). Read More

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http://dx.doi.org/10.1177/0333102419840777DOI Listing
April 2019
1 Read

Nummular Headache.

Curr Neurol Neurosci Rep 2019 Apr 17;19(6):26. Epub 2019 Apr 17.

Jefferson Headache Center, 900 Walnut Street, Suite 200, Philadelphia, PA, USA.

Purpose Of Review: This article reviews nummular headache (NH), including the latest literature on the epidemiological and clinical features, the most recent proposed pathophysiology, and novel management.

Recent Findings: NH is characterized by continuous or intermittent head pain confined to a focal circumscribed area (1-6 cm in diameter). It is usually of mild to moderate intensity, although some patients have severe continuous pain or disabling exacerbations. Read More

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http://dx.doi.org/10.1007/s11910-019-0943-xDOI Listing
April 2019
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Analysis of the Factors Affecting the Prognosis of Glioma Patients.

Open Med (Wars) 2019 4;14:331-335. Epub 2019 Apr 4.

Department of Neurosurgery, Zhangjiajie People's Hospital, 192 Guyong road, Zhangjiajie, Hunan, China 427000.

This retrospective study was carried out to investigate factors affecting the prognosis of gliomas for better management of treatment. Clinical data from 186 glioma patients treated in our hospital from January 2013 to June 2016 were analyzed. There was slightly more male than female patients in the cohort. Read More

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http://www.degruyter.com/view/j/med.2019.14.issue-1/med-2019
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http://dx.doi.org/10.1515/med-2019-0031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463817PMC
April 2019
1 Read

Relaxation training for management of paediatric headache: A rapid review.

Paediatr Child Health 2019 May 7;24(2):103-114. Epub 2019 Feb 7.

Department of Pediatrics, Faculty of Medicine & Dentistry, University of Alberta, Edmonton, Alberta.

The objective of this review was to assess the evidence on relaxation training for management of paediatric headaches. Our methodology was a rapid review of English-language peer reviewed published literature focused on studies evaluating relaxation training as a primary or adjunct management option for headache in a paediatric population (0 to 18 years of age). Seven studies involving 571 children were included in the review. Read More

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https://academic.oup.com/pch/article/24/2/103/5308619
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http://dx.doi.org/10.1093/pch/pxy157DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462122PMC
May 2019
1 Read

Migraine-like Headache after Transseptal Puncture for Catheter Ablation: A Case Report and Review of the Literature.

Intern Med 2019 Apr 17. Epub 2019 Apr 17.

Department of Neurology and Cerebrovascular Medicine, Saitama Medical University International Medical Center, Japan.

Catheter ablation for atrial fibrillation creates an iatrogenic atrial septal defect by transseptal puncture, which may produce a transient right-to-left shunt. We encountered a 44-year-old man who presented with de novo migraine-like headache after cryoballoon ablation for atrial fibrillation. On reviewing the literature, we found additional cases in which migraine-like headache occurred within one week after the procedure and spontaneously within three months. Read More

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http://dx.doi.org/10.2169/internalmedicine.2519-18DOI Listing
April 2019
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Diffusion Weighted Whole Body Imaging with Background Body Signal Suppression (DWIBS) Was Useful for the Diagnosis and Follow-Up of Giant Cell Arteritis.

Intern Med 2019 Apr 17. Epub 2019 Apr 17.

Department of Clinical Research, National Hospital Organization Osaka Minami Medical Center, Japan.

A 66-year-old woman with symptoms of fatigue and headache was diagnosed with giant cell arteritis (GCA). Fluorodeoxyglucose (FDG)-PET/computed tomography (CT) revealed the strong accumulation of FDG in the descending aorta, abdominal aorta, bilateral subclavian artery, and total iliac artery. Diffusion-weighted whole-body imaging with background body signal suppression (DWIBS) showed signal enhancement at the descending aorta and abdominal aorta. Read More

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http://dx.doi.org/10.2169/internalmedicine.2479-18DOI Listing
April 2019
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Isolated pontine involvement in posterior reversible encephalopathy syndrome with coincidental acute ischaemic stroke.

BMJ Case Rep 2019 Apr 16;12(4). Epub 2019 Apr 16.

DMOP, Basildon University Hospital, Basildon, Essex, UK.

Posterior reversible encephalopathy syndrome (PRES) is a cliniconeuroradiological syndrome characterised by a unique reversible pattern on imaging and total regression of clinical symptoms and signs. We describe an unusual case of PRES with isolated pontine involvement with coincidental acute ischaemic stroke in a 60-year-old man who presented with headache, unsteadiness of gait, blurred vision and elevated blood pressure. MRI scan revealed an expanded pons with diffuse T2 and Fluid attenuated Inversion Recovery (FLAIR) hyperintensities and an acute infarct in the right temporal lobe. Read More

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http://dx.doi.org/10.1136/bcr-2018-227132DOI Listing
April 2019
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Erenumab in chronic migraine: Patient-reported outcomes in a randomized double-blind study.

Neurology 2019 Apr 17. Epub 2019 Apr 17.

From the Department of Neurology (R.B.L.), Albert Einstein College of Medicine, Bronx, New York; Geisel School of Medicine at Dartmouth (S.J.T.), Hanover, NH; Department of Neurology (U.R.), Charité Universitätsmedizin Berlin, Germany; Jefferson Headache Center (S.S.), Thomas Jefferson University, Philadelphia, PA; Sutter Health (W.F.S.), Walnut Creek, CA; and Amgen Inc. (J.N., D.K.L., P.D., S.C., D.D.M., R.L.), Thousand Oaks, CA.

Objective: To determine the effect of erenumab, a human monoclonal antibody targeting the calcitonin gene-related peptide receptor, on health-related quality of life (HRQoL), headache impact, and disability in patients with chronic migraine (CM).

Methods: In this double-blind, placebo-controlled study, 667 adults with CM were randomized (3:2:2) to placebo or erenumab (70 or 140 mg monthly). Exploratory endpoints included migraine-specific HRQoL (Migraine-Specific Quality-of-Life Questionnaire [MSQ]), headache impact (Headache Impact Test-6 [HIT-6]), migraine-related disability (Migraine Disability Assessment [MIDAS] test), and pain interference (Patient-Reported Outcomes Measurement Information System [PROMIS] Pain Interference Scale short form 6b). Read More

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http://dx.doi.org/10.1212/WNL.0000000000007452DOI Listing

Erenumab in chronic migraine with medication overuse: Subgroup analysis of a randomized trial.

Neurology 2019 Apr 17. Epub 2019 Apr 17.

From the Geisel School of Medicine at Dartmouth (S.J.T.), Hanover, NH; Department of Neurology (H.-C.D.), University of Duisburg-Essen, Germany; Department of Neurology (M.A.), Danish Headache Center, Rigshospitalet Glostrup, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Department of Neurology (J.L.B.), Vanderbilt University School of Medicine; Nashville Neuroscience Group (J.L.B.), TN; Neurology and Neurotherapeutics and Ophthalmology (D.I.F.), University of Texas Southwestern Medical Center, Dallas; Department of Neurology (U.R.), Charité Universitätsmedizin Berlin, Germany; and Amgen Inc (S.C., J.N., D.K.L., R.A.L., D.D.M.), Thousand Oaks, CA.

Objective: To determine the effect of erenumab, a human anti-calcitonin gene-related peptide receptor monoclonal antibody, in patients with chronic migraine and medication overuse.

Methods: In this double-blind, placebo-controlled study, 667 adults with chronic migraine were randomized (3:2:2) to placebo or erenumab (70 or 140 mg), stratified by region and medication overuse status. Data from patients with baseline medication overuse at baseline were used to assess changes in monthly migraine days, acute migraine-specific medication treatment days, and proportion of patients achieving ≥50% reduction from baseline in monthly migraine days. Read More

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http://dx.doi.org/10.1212/WNL.0000000000007497DOI Listing
April 2019
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Relationship between changes in resting-state spontaneous brain activity and cognitive impairment in patients with CADASIL.

J Headache Pain 2019 Apr 17;20(1):36. Epub 2019 Apr 17.

Department of Neurology and Jiuyuan Municipal Stroke Center, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, 639 Zhizaoju Road, Shanghai, 200011, People's Republic of China.

Background: Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) mainly manifests with cognitive impairment. Cognitive deficits in patients with CADASIL are correlated with structural brain changes such as lacunar lesion burden, normalized brain volume, and anterior thalamic radiation lesions, but changes in resting-state functional brain activity in patients with CADASIL have not been reported.

Methods: This study used resting-state functional magnetic resonance imaging (fMRI) to measure the amplitude of low-frequency fluctuation (ALFF) in 22 patients with CADASIL and 44 healthy matched controls. Read More

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http://dx.doi.org/10.1186/s10194-019-0982-3DOI Listing

Therapeutic novelties in migraine: new drugs, new hope?

J Headache Pain 2019 Apr 17;20(1):37. Epub 2019 Apr 17.

Danish Headache Center and Department of Neurology, Rigshospitalet Glostrup, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark.

Background: In the past decade, migraine research has identified novel drug targets. In this review, we discuss recent data on emerging anti-migraine therapies.

Main Body: The development of ditans, gepants and anti-calcitonin gene-related peptide monoclonal antibodies for the treatment of migraine is one of the greatest advances in the migraine field. Read More

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https://thejournalofheadacheandpain.biomedcentral.com/articl
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http://dx.doi.org/10.1186/s10194-019-0974-3DOI Listing
April 2019
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A Review of the Role of Auditory Evoked Potentials in Mild Traumatic Brain Injury Assessment.

Trends Hear 2019 Jan-Dec;23:2331216519840094

3 Department of Communication Sciences and Disorders, University of North Carolina at Greensboro, NC, USA.

Around 75% to 90% of people who experience a traumatic brain injury (TBI) are classified as having a mild TBI (mTBI). The term mTBI is synonymous with concussion or mild head injury (MHI) and is characterized by symptoms of headache, nausea, dizziness, and blurred vision. Problems in cognitive abilities such as deficits in memory, processing speed, executive functioning, and attention are also considered symptoms of mTBI. Read More

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http://dx.doi.org/10.1177/2331216519840094DOI Listing
April 2019
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An Extended Endoscopic Endonasal Approach for Sellar Area Chondrosarcoma: A Case Report and Literature Review.

World Neurosurg 2019 Apr 14. Epub 2019 Apr 14.

Department of Neurosurgery, the First Affiliated Hospital of Fujian Medical University, Fuzhou, People's Republic of China.

Background: Chondrosarcoma is a malignant tumor that originates from mesenchymal cells that have differentiated into chondrocytes, often growing laterally, rarely seen in the cranium, and seldom seen in the saddle area. We believe that only a few cases have been reported in the literature. We report a case of pituitary fossa chondrosarcoma, which was completely resected by an extended endoscopic endonasal approach, and a literature review. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.04.075DOI Listing
April 2019
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A curious association of chronic homeopathic arsenic ingestion with nonspecific symptoms in a Swiss teenager.

Authors:
Sergio U Dani

Swiss Med Wkly 2019 Apr 17;149:w20071. Epub 2019 Apr 17.

Medawar Institute for Medical and Environmental Research, Acangau Foundation, Paracatu, MG, Brazil, and PizolCare Praxis Sargans, Switzerland.

Arsenic is a toxicant that has no dose threshold below which exposures are not harmful. Here I report a curious association of chronic homeopathic arsenic ingestion with nonspecific symptoms in a Swiss teenager. For about 4 years she had taken globules of a freely purchasable homeopathic remedy containing inorganic arsenic (iAs), infinitesimally diluted to D6 (average arsenic content per single globule: 0. Read More

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https://doi.emh.ch/smw.2019.20071
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http://dx.doi.org/10.4414/smw.2019.20071DOI Listing
April 2019
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Characteristics of children and adolescents at the Switzerland-wide first ambulatory interdisciplinary pain clinic at the University Children's Hospital Basel - a retrospective study.

Swiss Med Wkly 2019 Apr 17;149:w20073. Epub 2019 Apr 17.

Pain Therapy Unit, Department for Anaesthesia, Surgical Intensive Care, Prehospital Emergency Medicine and Pain Therapy, University Hospital Basel, Switzerland.

Aims Of The Study: Given the long history of underestimating chronic pain in children and adolescents, we lack valid data on its assessment and treatment. The psychological and economic burden for patients, their families and society is substantial. The aim of this study was to assess patient characteristics of the first ambulatory interdisciplinary clinic for children and adolescents with chronic pain in Switzerland and compare them with data from other international centres. Read More

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http://dx.doi.org/10.4414/smw.2019.20073DOI Listing

Clinical predictors of symptom resolution for children and adolescents with sport-related concussion.

J Neurosurg Pediatr 2019 Apr 16:1-8. Epub 2019 Apr 16.

1Sports Medicine Center and.

OBJECTIVEThe goal of this study was to determine which variables assessed during an initial clinical evaluation for concussion are independently associated with time until symptom resolution among pediatric patients.METHODSData collected from a prospective clinical registry of pediatric patients with concussion were analyzed. The primary outcome variable was time from injury until symptom resolution. Read More

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http://dx.doi.org/10.3171/2018.11.PEDS18626DOI Listing
April 2019
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Acute Community-Acquired Bacterial Meningitis: Update on Clinical Presentation and Prognostic factors.

New Microbiol 2019 Apr 17;41(2). Epub 2019 Apr 17.

Department of Infectious Diseases, Hospital Fundación Jiménez-Díaz, Universidad Autonoma, Madrid, Spain.

The epidemiology of community-acquired bacterial meningitis (CABM) in adults has changed significantly in the past several years. Despite substantial improvement in patient care, CABM remains a major cause of morbidity and mortality. Thus, new prognostic factors could help improve patient stratification. Read More

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April 2019
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Cerebral venous thrombosis in adults.

Vasa 2019 Apr 17:1-10. Epub 2019 Apr 17.

1 Vivantes Klinikum im Friedrichshain, Berlin, Germany.

Thromboses of cerebral veins and/or sinuses (CVT) encompass a clinically rather heterogenous, relatively rare entity, which is nonetheless an important cause of stroke in the young. While until the mid of the last century the prognosis of CVT was thought to be poor or even fatal in the majority of cases, the advance and wider use of modern imaging technology since the early 1980s, together with the results of registries and population-based studies, revealed that CVT is more frequent and less life-threatening than previously assumed. However, because headache is frequently the only symptom, many oligosymptomatic cases might be overlooked. Read More

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https://econtent.hogrefe.com/doi/10.1024/0301-1526/a000788
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http://dx.doi.org/10.1024/0301-1526/a000788DOI Listing
April 2019
2 Reads

CADASIL with Atypical Clinical Symptoms, Magnetic Resonance Imaging, and Novel Mutations: Two Case Reports and a Review of the Literature.

J Mol Neurosci 2019 Apr 16. Epub 2019 Apr 16.

Department of Neurology, Celal Bayar University, 45000, Manisa, Turkey.

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a hereditary microangiopathy with adult onset caused by a missense mutation in the NOTCH3 gene in chromosome 19p13. It presents with autosomal dominant arteriopathy, subcortical infarctions, and leukoencephalopathy. Its common clinical presentations are seen as recurrent strokes, migraine or migraine-like headaches, progressive dementia, pseudobulbar paralysis, and psychiatric conditions. Read More

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http://dx.doi.org/10.1007/s12031-019-01313-zDOI Listing