604,352 results match your criteria Head & Neck[Journal]


Anterolateral Thigh Flap in a Chicken Model: A Novel Perforator Training Model.

J Reconstr Microsurg 2019 Feb 22. Epub 2019 Feb 22.

Department of Human Pathology of the Adult, the Child and the Adolescent, University of Messina, Messina, Italy.

Background:  Preclinical training in perforator flap harvesting is typically conducted on living animal models; however, repeated training is not possible with these models because of ethical and/or economical constraints. We describe an anterolateral thigh flap (ALT flap) training model using chicken thigh that seems to be an appropriate training model prior, for example, to raise a perforator flap in a living rat or swine model.

Methods:  A total of 10 chicken legs were used in this study. Read More

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http://dx.doi.org/10.1055/s-0039-1679882DOI Listing
February 2019

Toward Tissue-engineering of Nasal Cartilages.

Acta Biomater 2019 Feb 19. Epub 2019 Feb 19.

Department of Biomedical Engineering, University of California Irvine, 3120 Natural Sciences II, Irvine, CA, 92697-2715, USA. Electronic address:

Nasal cartilage pathologies are common; for example, up to 80% of people are afflicted by deviated nasal septum conditions. Because cartilage provides the supportive framework of the nose, afflicted patients suffer low quality of life. To correct pathologies, graft cartilage is often required. Read More

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http://dx.doi.org/10.1016/j.actbio.2019.02.025DOI Listing
February 2019

Cerebral granuloma mimicking malignant neoplasm in a patient with seizures 21 years after head trauma.

World Neurosurg 2019 Feb 19. Epub 2019 Feb 19.

Department of Neurosurgery, The Affliated Hospital of Southwest Medical University, Luzhou, Sichuan 646000, P.R. China. Electronic address:

Background: Chronic post-traumatic cerebral granuloma is a rare, delayed complication of traumatic brain injury. Because of its late onset of symptoms and atypical appearance, the correct diagnosis of this rare lesion is difficult.

Case Report: A 49-year-old man presented with seizures, which occured 21 years after open right forehead trauma. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.01.286DOI Listing
February 2019

Unilateral Thalamic Deep Brain Stimulation vs. Focused Ultrasound Thalamotomy for Essential Tremor.

World Neurosurg 2019 Feb 19. Epub 2019 Feb 19.

Departments of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.

Background: The predominant neurosurgical approach to medication-refractory essential tremor (ET) is thalamic deep brain stimulation (DBS). The emergence of magnetic resonance-guided focused ultrasound (MRgFUS) thalamotomy has reawakened the debate surrounding the use of DBS vs. thalamotomy for this indication. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.01.281DOI Listing
February 2019

Diurnal rhythm and pathogens induced expression of toll-like receptor 9 (TLR9) in Pelteobagrus vachellii.

Fish Shellfish Immunol 2019 Feb 19. Epub 2019 Feb 19.

College of Life Science, Neijiang Normal University, Key Laboratory of Sichuan Province for Fishes Conservation and Utilization in the Upper Reaches of the Yangtze River, Neijiang, 641000, PR China.

Toll-like receptor 9 (TLR9) is activated by bacterial DNA and induces the production of inflammatory cytokines. In this study, the darkbarbel catfish Pelteobagrus vachellii TLR9 cDNA was cloned and sequenced. The daily expression pattern of TLR9 mRNA was investigated in various tissues. Read More

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http://dx.doi.org/10.1016/j.fsi.2019.02.038DOI Listing
February 2019

Common pathogenic mechanism in patients with dropped head syndrome caused by different mutations in the MYH7 gene.

Gene 2019 Feb 19. Epub 2019 Feb 19.

Medical Genetics Laboratory, Petrovsky Russian Research Center of Surgery, Moscow 119991, Russia; Pirogov Russian National Research Medical University, Moscow 117997, Russia.

Mutations in the MYH7 gene are the source of an allelic series of diseases, including various cardiomyopathies and skeletal myopathies that usually manifest in adulthood. We observed a 1.5 y. Read More

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http://dx.doi.org/10.1016/j.gene.2019.02.011DOI Listing
February 2019

Deep Parotid Lymph Node Metastasis Is Associated With Recurrence in High-Grade Mucoepidermoid Carcinoma of the Parotid Gland.

J Oral Maxillofac Surg 2019 Jan 30. Epub 2019 Jan 30.

Professor and Department Head, Department of Head and Neck, Affiliated Cancer Hospital of Zhengzhou University, Henan Cancer Hospital, Zhengzhou, China.

Purpose: The goal of the present study was to assess the association between intraparotid lymph node (IPN) metastasis and prognosis in high-grade mucoepidermoid carcinoma (MEC) of the parotid gland.

Patients And Methods: Patients with surgically treated primary high-grade MEC of the parotid gland were retrospectively enrolled. The association between IPN metastasis and clinicopathologic variables was analyzed using χ tests, and recurrence-free survival (RFS) rate was calculated by the Kaplan-Meier method; independent prognostic factors were evaluated by the Cox proportional hazards method. Read More

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http://dx.doi.org/10.1016/j.joms.2019.01.031DOI Listing
January 2019

Oral Cancer Treatment Through the Ages: Part 1.

J Oral Maxillofac Surg 2019 Jan 28. Epub 2019 Jan 28.

Consultant Oral and Maxillofacial Head and Neck Surgeon, Northampton General Hospital, Cliftonville, Northampton, UK.

There is substantial literature exploring the history of various aspects of oncology, spanning multiple languages and across continents. However, there are no articles describing the comprehensive development of oral cancer management throughout the ages. The present article attempts to chart the history of oral cancer and its associated surgical concepts, with the aim of providing a general overview of key events and prominent figures. Read More

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http://dx.doi.org/10.1016/j.joms.2019.01.023DOI Listing
January 2019

Oral Cancer Treatment Through the Ages: Part 2.

J Oral Maxillofac Surg 2019 Jan 28. Epub 2019 Jan 28.

Consultant Oral and Maxillofacial Head and Neck Surgeon, Northampton General Hospital, Cliftonville, United Kingdom.

In part 1, we learned the foundations of oral cancer and principles of treatment as described by prominent early surgeons and physicians from Hippocrates and Celsus to Henry T. Butlin, the prominent head and neck surgeon. Part 2 commences with the turn of the 20th century and focuses on the evolution of neck dissection, as well as adjunctive treatment options, leading to the reconstructive revolution with a growing focus on quality of life. Read More

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http://dx.doi.org/10.1016/j.joms.2019.01.024DOI Listing
January 2019

The Developmental Characteristics for the Head Capsule Width of Monochamus alternatus (Coleoptera: Cerambycidae) Larvae and Determination of the Number of Instars.

J Insect Sci 2019 Jan;19(1)

Major of Plant Resources Science and Environment, College of Agriculture & Life Sciences, SARI, Jeju National University, Jeju, South Korea.

The objective of this study was to determine the number of instars of Monochamus alternatus Hope (Coleoptera: Cerambycidae) larvae by comparing their head capsule widths (HCW) published in previous studies, as well as additional laboratory experiments. Larvae of M. alternatus showed repeated molting in the laboratory. Read More

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http://dx.doi.org/10.1093/jisesa/iez010DOI Listing
January 2019

Nasal microbial composition and chronic otitis media with effusion: A case-control study.

PLoS One 2019 22;14(2):e0212473. Epub 2019 Feb 22.

Department of Paediatrics: Child and Youth Health, The University of Auckland, Auckland, New Zealand.

Objectives: Chronic otitis media with effusion (COME) in children can cause prolonged hearing loss, which is associated with an increased risk of learning delays and behavioural problems. Dispersal of bacterial pathogens from the nasal passages to the middle ear is implicated in COME. We sought to determine whether there is an association between nasal microbial composition and COME in children. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0212473PLOS
February 2019

Changes in the temporal distribution of in-hospital mortality in severely injured patients-An analysis of the TraumaRegister DGU.

PLoS One 2019 22;14(2):e0212095. Epub 2019 Feb 22.

Department of Trauma Surgery, Technical University Munich, Hospital Rechts der Isar, Munich, Germany.

Background: The temporal distribution of trauma mortality has been classically described as a trimodal pattern with an immediate, early and late peak. In modern health care systems this time distribution has changed.

Methods: Data from the TraumaRegister DGU was analysed retrospectively. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0212095PLOS
February 2019

Genome-wide association studies for yield-related traits in soft red winter wheat grown in Virginia.

PLoS One 2019 22;14(2):e0208217. Epub 2019 Feb 22.

Department Of Crop and Soil Environmental Sciences, Virginia Tech, Blacksburg, Virginia, United States of America.

Grain yield is a trait of paramount importance in the breeding of all cereals. In wheat (Triticum aestivum L.), yield has steadily increased since the Green Revolution, though the current rate of increase is not forecasted to keep pace with demand due to growing world population and increasing affluence. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0208217PLOS
February 2019

Multi-User Redirected Walking and Resetting Using Artificial Potential Fields.

IEEE Trans Vis Comput Graph 2019 Feb 20. Epub 2019 Feb 20.

Head-mounted displays (HMDs) and large area position tracking systems can enable users to navigate virtual worlds through natural walking. Redirected walking (RDW) imperceptibly steers immersed users away from physical world obstacles allowing them to explore unbounded virtual worlds while walking in limited physical space. In cases of imminent collisions, resetting techniques can reorient them into open space. Read More

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http://dx.doi.org/10.1109/TVCG.2019.2898764DOI Listing
February 2019

Commercially Available Friction-Reducing Patient-Transfer Devices Reduce Biomechanical Stresses on Caregivers' Upper Extremities and Low Back.

Hum Factors 2019 Feb 22:18720819827208. Epub 2019 Feb 22.

Oregon State University, Corvallis, USA.

Objective:: The aim of this study was to evaluate the efficacy of commercially available friction-reducing patient-transfer devices in reducing biomechanical stresses on caregivers and patients.

Background:: Caregivers suffer from high prevalence of work-related musculoskeletal disorders, which is associated with manual patient handling. However, there is not enough information available on the efficacy of various friction-reducing devices in reducing biomechanical stresses in the upper extremities and low back. Read More

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http://dx.doi.org/10.1177/0018720819827208DOI Listing
February 2019

3D-printed, externally-implanted, bioresorbable airway splints for severe tracheobronchomalacia.

Laryngoscope 2019 Feb 22. Epub 2019 Feb 22.

Department of Otolaryngology-Head and Neck Surgery, University of Michigan, Ann Arbor, Michigan.

Objectives/hypothesis: To report the clinical safety and efficacy of three-dimensional (3D)-printed, patient-specific, bioresorbable airway splints in a cohort of critically ill children with severe tracheobronchomalacia.

Study Design: Case series.

Methods: From 2012 to 2018, 15 subjects received 29 splints on their trachea, right and/or left mainstem bronchi. Read More

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http://dx.doi.org/10.1002/lary.27863DOI Listing
February 2019

Recurrence patterns of sinonasal cancers after a 5-year disease-free period.

Laryngoscope 2019 Feb 22. Epub 2019 Feb 22.

Department of Otorhinolaryngology-Head and Neck Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.

Objectives/hypothesis: Sinonasal cancers are rare but have a poor prognosis. Most previous studies of these cancers have focused on 5-year disease-free survival, but recurrences are also known to occur after this period. We examined the post-5-year recurrence patterns in sinonasal cancer patients by histologic type to determine the indicators for extended and close follow-up requirements. Read More

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http://dx.doi.org/10.1002/lary.27866DOI Listing
February 2019

Is there a Threshold that Triggers Cortical Arousals in Obstructive Sleep Apnea.

Sleep 2019 Feb 22. Epub 2019 Feb 22.

Pulmonary, Critical Care and Sleep Division. University of California at San Diego, CA, United States.

Study Objectives: To determine whether there is a consistent epiglottic pressure value that predicts respiratory arousal from sleep.

Methods: 31 patients with obstructive sleep apnea underwent overnight polysomnography while instrumented with an epiglottic catheter to measure airway pressures. Nadir epiglottic pressures during respiration events (obstructive apneas/hypopneas) terminated with or without arousals were compared. Read More

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http://dx.doi.org/10.1093/sleep/zsz047DOI Listing
February 2019

Microbiome signatures in prostate cancer.

Carcinogenesis 2019 Feb 22. Epub 2019 Feb 22.

Department of Otorhinolaryngology-Head and Neck Surgery, University of Pennsylvania, Philadelphia, PA, USA.

We have established a microbiome signature for prostate cancer using an array-based metagenomic and capture-sequencing approach. A diverse microbiome signature (viral, bacterial, fungal and parasitic) was observed in the prostate cancer samples compared with benign prostate hyperplasia controls. Hierarchical clustering analysis identified three distinct prostate cancer-specific microbiome signatures. Read More

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http://dx.doi.org/10.1093/carcin/bgz008DOI Listing
February 2019

Can We Avoid Implant-selection Errors in Total Joint Arthroplasty?

Clin Orthop Relat Res 2019 Jan;477(1):130-133

M. P. Ast, Hospital for Special Surgery, New York, NY, USA D. J. Mayman, M. P. Bostrom, A. Gonzalez Della Valle, S. B. Haas, Hospital for Special Surgery, New York, NY.

Background: Implant selection in the operating room is a manual process. This manual process combined with complex compatibility rules and inconsistent implant labeling may lead to implant-selection errors. These might be reduced using an automated process; however, little is known about the efficacy of available automated error-reduction systems in the operating room. Read More

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http://dx.doi.org/10.1097/CORR.0000000000000536DOI Listing
January 2019

Editorial Comment: 2018 Knee Society Proceedings.

Clin Orthop Relat Res 2019 Jan;477(1):39-40

D. J. Backstein, Head, Granovsky Gluskin Division of Orthopaedic Surgery, Sinai Health System, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1097/CORR.0000000000000573DOI Listing
January 2019

What Is the Survivorship of Revision Surgery Performed for the Chronically Dislocated THA?

Clin Orthop Relat Res 2019 Feb;477(2):374-379

T. S. Brown, R. J. McLaughlin, D. J. Berry, D. G. Lewallen, R. T. Trousdale, R. J. Sierra, Department of Orthopedic Surgery, Mayo Clinic, Rochester, MN, USA.

Background: Instability remains one of the most common indications for revision THA. However, little is known about the efficacy of surgery for and the complications associated with revision THA for patients with a chronically dislocated THA, which we define as a dislocation of more than 4 weeks.

Questions/purposes: For patients with a chronically dislocated THA undergoing revision THA, we asked (1) What is the survivorship free from additional revision for these procedures? (2) What complications are associated with revision THA in this setting? (3) What are the clinical outcomes as measured by the Harris hip score in these procedures?

Methods: From 1998 to 2014, 1084 patients who underwent revision THA for instability were reviewed and 33 patients (33 hips) were identified who had a hip that had been dislocated for more than 4 weeks. Read More

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http://dx.doi.org/10.1097/CORR.0000000000000392DOI Listing
February 2019

Revisions of Modular Metal-on-metal THA Have a High Risk of Early Complications.

Clin Orthop Relat Res 2019 Feb;477(2):344-350

J. M. Jennings, C. C. Yang, T. M. Miner, D. A. Dennis, Colorado Joint Replacement, Denver, CO, USA S. White, Icahn School of Medicine at Mount Sinai, New York, NY, USA J. R. Martin, OrthoCarolina, Charlotte, NC, USA J. M. Jennings, D. A. Dennis, Department of Mechanical and Materials Engineering, University of Denver, Denver, CO, USA D. A. Dennis, Department of Orthopaedics, University of Colorado School of Medicine, Denver, CO, USA; and the Department of Biomedical Engineering, University of Tennessee, Knoxville, TN, USA.

Background: The risk of early complications is high after monoblock acetabular metal-on-metal (MoM) THA revisions. However, there is a paucity of evidence regarding clinical complications after isolated head-liner exchange of modular MoM THA.

Questions/purposes: The purposes of this study were (1) to describe the frequency of early complications after an isolated head-liner exchange revision of modular MoM THA; and (2) to determine whether patients who experienced complications or dislocation after head-liner exchanges had higher serum chromium (Cr) or cobalt (Co) ion levels than those who did not. Read More

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http://dx.doi.org/10.1097/CORR.0000000000000363DOI Listing
February 2019

Does Extracorporeal Irradiation and Reimplantation After Acetabular Resections Result in Adequate Hip Function? A Preliminary Report.

Clin Orthop Relat Res 2018 Sep;476(9):1738-1748

M. G. Agarwal, M. K. Gundavda, R. Reddy Orthopedic Oncology, P. D. Hinduja Hospital and Medical Research Center, Mumbai, India R. Gupta Orthopedic Oncology, Fortis Hospital, Mohali, India.

Background: Pelvic resections are challenging, and reconstruction of the resected acetabulum to restore mobility and stability is even more difficult. Extracorporeal radiation therapy (ECRT or extracorporeal irradiation) of autograft bone and reimplantation allows for a perfect size match and has been used with some success in the extremities. Although the risk of wound complications in pelvic surgery has discouraged surgeons from using ECRT of autografts in that anatomic site, we believe it may be a reasonable option. Read More

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http://dx.doi.org/10.1007/s11999.0000000000000103DOI Listing
September 2018

An Early Disc Herniation Identification System for Advancement in the Standard Medical Screening Procedure based on Bayes Theorem.

IEEE J Biomed Health Inform 2019 Feb 15. Epub 2019 Feb 15.

The aim of this research was to analyze objectively the process of disc herniation identification using Bayes Theorem. One of the symptoms of discus hernia is muscle weakness on the foot that is caused by displaced discs in the space of two vertebrae. This fact is used by experts in initial diagnosis of herniated discs and we used it to create non-invasive platform for the same purposes by measuring force values from four sensors placed on both feet (first, second and fourth metatarsal head as well as the heel). Read More

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http://dx.doi.org/10.1109/JBHI.2019.2899665DOI Listing
February 2019

SGaze: A Data-Driven Eye-Head Coordination Model for Realtime Gaze Prediction.

IEEE Trans Vis Comput Graph 2019 Feb 18. Epub 2019 Feb 18.

We present a novel, data-driven eye-head coordination model that can be used for realtime gaze prediction for immersive HMD-based applications without any external hardware or eye tracker. Our model (SGaze) is computed by generating a large dataset that corresponds to different users navigating in virtual worlds with different lighting conditions. We perform statistical analysis on the recorded data and observe a linear correlation between gaze positions and head rotation angular velocities. Read More

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http://dx.doi.org/10.1109/TVCG.2019.2899187DOI Listing
February 2019

Can AI Help Reduce Disparities in General Medical and Mental Health Care?

AMA J Ethics 2019 Feb 1;21(2):E167-179. Epub 2019 Feb 1.

An assistant professor of computer science and medicine at the University of Toronto and a faculty member at the Vector Institute, both in in Ontario, Canada; and previously served as a visiting researcher at Alphabet Inc. within its life sciences research organization, Verily, and as a postdoctoral fellow at the Massachusetts Institute of Technology.

Background: As machine learning becomes increasingly common in health care applications, concerns have been raised about bias in these systems' data, algorithms, and recommendations. Simply put, as health care improves for some, it might not improve for all.

Methods: Two case studies are examined using a machine learning algorithm on unstructured clinical and psychiatric notes to predict intensive care unit (ICU) mortality and 30-day psychiatric readmission with respect to race, gender, and insurance payer type as a proxy for socioeconomic status. Read More

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http://dx.doi.org/10.1001/amajethics.2019.167DOI Listing
February 2019

Clinical outcomes of platinum-based chemotherapy plus cetuximab for recurrent or metastatic squamous cell carcinoma of the head and neck: comparison between platinum-sensitive and platinum-resistant patients.

Acta Otolaryngol 2019 Feb 22:1-5. Epub 2019 Feb 22.

c Department of Head and Neck Oncology and Surgery , International University of Health and Welfare Mita Hospital , Tokyo, Japan.

Background: Combination therapy consisting of a platinum agent, 5-fluorouracil and cetuximab (EXTREME regimen) is recommended for recurrent or metastatic squamous cell carcinoma of the head and neck (R/M-SCCHN). However, it is advisable to use platinum-free regimens as first-line therapy in patients resistant to platinum agents. There has been no report comparing EXTREME regimen outcomes between platinum-resistant and platinum-sensitive patients. Read More

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http://dx.doi.org/10.1080/00016489.2018.1551623DOI Listing
February 2019

Post-operative complications of salvage total laryngectomy forpost-radiotherapy recurrent laryngeal cancer using pectoralis major myocutaneous flaps.

Acta Otolaryngol 2019 Feb 22:1-5. Epub 2019 Feb 22.

a Department of Otolaryngology, Head and Neck Surgery , Tokyo Medical University , Shinjuku-ku , Tokyo , Japan.

Background: Salvage surgery for laryngeal cancer recurring after radiotherapy is difficult and complications readily occur. Our institution has adopted the pharyngeal interposition graft (PIG) using a pectoralis major myocutaneous (PMMC) flap, which has copious blood flow, for preventing post-irradiation pharyngocutaneous fistula.

Aims/objectives: The purpose of this study was to examine the incidence of post-operative complications of salvage total laryngectomy (STL) using the PMMC flap for post-radiotherapy recurrent laryngeal cancer at our institution. Read More

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http://dx.doi.org/10.1080/00016489.2018.1532108DOI Listing
February 2019

TLR5 and TLR7 are differentially expressed in human papillomavirus-positive and negative base of tongue squamous cell carcinoma, and TLR7 may have an independent prognostic influence.

Acta Otolaryngol 2019 Feb 22:1-5. Epub 2019 Feb 22.

a Department of Oncology-Pathology , Karolinska Institute, CCK , Stockholm , Sweden.

Background: Human papillomavirus-positive (HPV) base of tongue squamous cell carcinoma (BOTSCC) has a better outcome than corresponding HPV cancer. TLR5 and TLR7 expression was previously shown to differ depending on HPV - status and correlate with outcome in oropharyngeal squamous cell carcinoma.

Aims/objectives: For validation, TLR5 and TLR7 were analyzed in a BOTSCC-cohort for correlation with HPV, survival, CD4 and CD8 tumor-infiltrating lymphocyte (TIL) counts, the latter being a well-documented prognostic marker. Read More

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http://dx.doi.org/10.1080/00016489.2018.1552014DOI Listing
February 2019

Assessment of preoperative psychologic distress in laryngeal cancer patients.

Acta Otolaryngol 2019 Feb 22:1-3. Epub 2019 Feb 22.

a Department of Anaesthesiology, The Eye Ear Nose and Throat Hospital , Fudan University , Shanghai , China.

Background: Preoperative psychologic distress is common in head and neck cancer patients and related to deleterious effects in patient treatment and recovery. Routine screening and appropriate referral of all patients with cancer for psychiatric assessment is now a part of the medical treatment.

Objects: The aim was to assess the level of preoperative psychologic distress in laryngeal cancer patients scheduled for surgical treatment. Read More

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http://dx.doi.org/10.1080/00016489.2018.1523555DOI Listing
February 2019

Anatomical study of presigmoid-retrolabyrinthine approach based on temporal bone high-resolution CT.

Acta Otolaryngol 2019 Feb 22:1-5. Epub 2019 Feb 22.

b Department of Radiology , Beijing Tongren Hospital, Affiliate of Capital Medical , Beijing , China.

Background: The surgical approach of acoustic neuroma includes translabyrinthine, transcranial fossa, suboccipital retrosigmoid sinus, and presigmoid retrolabyrinthine approach. Aims/Objective: To provide the anatomical basis for the surgical selection of presigmoid retrolabyrinthine approach by measuring the anatomical parameters of retrolabyrinthine space of the petrous bone by high-resolution CT.

Material And Methods: A retrospective study of 208 high-resolution CT (HRCT) images of 104 patients examined in our hospital were analyzed retrospectively. Read More

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http://dx.doi.org/10.1080/00016489.2018.1550585DOI Listing
February 2019

Prospective multi-center study on expansion sphincter pharyngoplasty.

Acta Otolaryngol 2019 Feb 22:1-4. Epub 2019 Feb 22.

d Department of Otolaryngology , Asia Sleep Centre, Paragon Medical Centre , Singapore.

Background And Objective: The aim of this study was to demonstrate the long-term effectiveness of Expansion Sphincter Pharyngoplasty (ESP) as a standalone surgical treatment of obstructive sleep apnea-hypopnea syndrome (OSAHS) patients through a prospective multi-center study.

Material And Methods: A prospective non-comparative multicenter study of patients suffering from OSHAS selected after drug-induced sleep endoscopy, with ESP as standing alone procedure was performed. Inclusion criteria were lateral collapse on oropharynx and preoperative AHI between 5 and 70. Read More

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http://dx.doi.org/10.1080/00016489.2018.1533992DOI Listing
February 2019

Effects of forefoot arthroplasty on plantar pressure, pain, gait and disability in rheumatoid arthritis.

Mod Rheumatol 2019 Feb 22:1-13. Epub 2019 Feb 22.

a Department of Rehabilitation , Yokohama City University Medical Center , Kanagawa , Japan.

Objectives: The purpose of this study was to clarify the effect of forefoot arthroplasty on plantar pressure, pain, gait, and disability within one year after arthroplasty in patients with RA.

Methods: Eleven patients with RA who underwent forefoot arthroplasty completed this quasi-experimental study. Outcome measures were in-shoe plantar pressure, visual analog scale (VAS) for pain, temporal gait parameters, and modified Health Assessment Questionnaire (mHAQ), obtained preoperatively and at 4 and 12 months postoperatively. Read More

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http://dx.doi.org/10.1080/14397595.2019.1584951DOI Listing
February 2019

Prior head injury but not sex or sports-participation affects expectations for post-injury rest and activity in simulated mild traumatic brain injury.

Appl Neuropsychol Adult 2019 Feb 22:1-9. Epub 2019 Feb 22.

a School of Psychology and Counselling , Queensland University of Technology (QUT) , Brisbane , Queensland , Australia.

Rest acutely followed by a gradual return to activity is commonly recommended for mild traumatic brain injury (TBI). However, the general public's rest and activity expectations for this injury are unknown, as are the individual factors that might affect them. 165 individuals completed an online survey. Read More

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http://dx.doi.org/10.1080/23279095.2018.1433180DOI Listing
February 2019

The Society for Craniofacial Genetics and Developmental Biology 41st Annual Meeting.

Am J Med Genet A 2019 Feb 22. Epub 2019 Feb 22.

Stowers Institute for Medical Research, Kansas City, Missouri.

The mission of the Society for Craniofacial Genetics and Developmental Biology (SCGDB) is to promote education, research, and communication about normal and abnormal development of the tissues and organs of the head. The SCGDB welcomes as members undergraduate students, graduate students, postdoctoral researchers, medical and dental practitioners, scientists, and academicians who possess an interest in craniofacial biology. Each year our members come together to share their novel findings, build upon, and challenge current knowledge of craniofacial biology. Read More

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http://dx.doi.org/10.1002/ajmg.a.61090DOI Listing
February 2019

Volume Assessment of the Effect of Obturators on Facial Form Following Surgery for Head and Neck Cancer Using Stereophotogrammetry.

J Prosthodont 2019 Feb 22. Epub 2019 Feb 22.

Academic Centre of Reconstructive Science, Kings College London, UK.

Purpose: To determine if stereophotogrammetry could be used to determine the effects of obturators on facial contour in relation to the measurement of facial volumes.

Materials And Methods: Stereophotogrammetry images were recorded from 20 subjects with and without their obturators in place. These were converted into a stereolithographic format and overlaid. Read More

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http://dx.doi.org/10.1111/jopr.13041DOI Listing
February 2019

Evolution of self-perceived swallowing function, tongue strength and swallow-related quality of life during radiotherapy in head and neck cancer patients.

Head Neck 2019 Feb 14. Epub 2019 Feb 14.

Department of Otolaryngology and Head and Neck Surgery - Rehabilitation Center for Communication Disorders, Antwerp University Hospital, Antwerp, Belgium.

Background: Radiation-associated-dysphagia is a serious side effect of radiotherapy (RT) for head and neck cancer (HNC).

Methods: Seventy-six patients had a weekly prospective follow-up from baseline until one week post-RT. Combined mixed model analysis (n = 43) determined the evolution of self-perceived swallowing function, isometric tongue strength (MIP), tongue strength (TS) during swallowing (Pswal), and quality of life (QoL) in these patients during RT. Read More

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http://dx.doi.org/10.1002/hed.25684DOI Listing
February 2019

Metastasis of cutaneous squamous cell carcinoma in organ transplant recipients and the immunocompetent population: is there a difference? a systematic review and meta-analysis.

J Eur Acad Dermatol Venereol 2019 Feb 22. Epub 2019 Feb 22.

Department of dermatology, Leiden University Medical Centre, Leiden, the Netherlands.

Background: Organ transplant recipients (OTR) have a higher risk of developing cutaneous squamous cell carcinoma (cSCC) compared to the immunocompetent population. Immunosuppression is often stated as a risk factor for metastasis. However, evidence for this is scarce. Read More

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http://dx.doi.org/10.1111/jdv.15396DOI Listing
February 2019

Outcomes of surgical treatment for hemangiomas.

Pediatr Dermatol 2019 Feb 22. Epub 2019 Feb 22.

Department of Biostatistics & Bioinformatics, Duke University, Durham, North Carolina.

Objective: To quantify complications and rates of adverse events associated with surgical excision of hemangiomas in children using a national surgical database.

Data Source: Pediatric American College of Surgeons (ACS) National Surgical Quality Improvement Program (ACS NSQIP -pediatric), years 2012-2016.

Methods: Subjects included children under 18 years with a postoperative diagnosis of International Classification of Diseases (ICD), 9th revision code: 228. Read More

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http://dx.doi.org/10.1111/pde.13751DOI Listing
February 2019

Shared extremes by ectotherms and endotherms: body elongation in mustelids is associated with small size and reduced limbs.

Evolution 2019 Feb 22. Epub 2019 Feb 22.

Department of Ecology and Evolutionary Biology, Coastal Biology Building, University of California, Santa Cruz, 130 McAllister Road, Santa Cruz, CA, 95060, USA.

An elongate body with reduced or absent limbs has evolved independently in many ectothermic vertebrate lineages. While much effort has been spent examining the morphological pathways to elongation in these clades, quantitative investigations into the evolution of elongation in endothermic clades are lacking. We quantified body shape in 61 musteloid mammals (red panda, skunks, raccoons, and weasels) using the head-body elongation ratio. Read More

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http://dx.doi.org/10.1111/evo.13702DOI Listing
February 2019

Development of an integrated multimodal optical imaging system with real-time image analysis for the evaluation of oral premalignant lesions.

J Biomed Opt 2019 Feb;24(2):1-10

Rice University, Department of Bioengineering, Houston, Texas, United States.

Oral premalignant lesions (OPLs), such as leukoplakia, are at risk of malignant transformation to oral cancer. Clinicians can elect to biopsy OPLs and assess them for dysplasia, a marker of increased risk. However, it is challenging to decide which OPLs need a biopsy and to select a biopsy site. Read More

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http://dx.doi.org/10.1117/1.JBO.24.2.025003DOI Listing
February 2019

The neuroplastic effect of olfactory training to the recovery of olfactory system in mouse model.

Int Forum Allergy Rhinol 2019 Feb 21. Epub 2019 Feb 21.

Department of Otorhinolaryngology-Head and Neck Surgery, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.

Background: Several studies have reported the benefits of olfactory training (OT) in the olfactory nervous system of mouse models. Therefore, in this study we performed next-generation sequencing to evaluate the effects of OT on mRNA sequencing in the olfactory area.

Methods: Mice in each group were administered 300 mg of 3-methylindole per kilogram of mouse weight. Read More

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http://dx.doi.org/10.1002/alr.22320DOI Listing
February 2019

Body mass index, body shape, and risk of nasopharyngeal carcinoma: A population-based case-control study in Southern China.

Cancer Med 2019 Feb 21. Epub 2019 Feb 21.

Department of Cancer Prevention Center, Sun Yat-sen University Cancer Center, Guangzhou, China.

Whether the association between body size or shape and nasopharyngeal carcinoma (NPC) risk exists or varies by age-specific body size indicators is unclear. In a population-based case-control study conducted in Southern China between 2010 and 2014, self-reported height, weight, and body shape at age 20 and 10 years before interview were collected from 2448 histopathologically confirmed NPC cases and 2534 population-based controls. Body mass index (BMI) was categorized according to the World Health Organization guidelines for Asian populations: underweight (<18. Read More

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http://dx.doi.org/10.1002/cam4.2027DOI Listing
February 2019

Separation of betacyanins from flowers of Amaranthus cruentus L. in a polar solvent system by high-speed counter-current chromatography.

J Sep Sci 2019 Feb 21. Epub 2019 Feb 21.

Department of Analytical Chemistry, Institute C-1, Faculty of Chemical Engineering and Technology, Cracow University of Technology, Cracow, Poland.

Betacyanin extract of Amaranthus cruentus L. flowers was fractionated for the first time by semi-preparative high-speed counter-current chromatography in highly polar solvent system: Propan-1-ol - Acetonitrile - (NH ) SO - H O (1.0:0. Read More

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http://dx.doi.org/10.1002/jssc.201801172DOI Listing
February 2019

EED and EZH2 constitutive variants: A study to expand the Cohen-Gibson syndrome phenotype and contrast it with Weaver syndrome.

Am J Med Genet A 2019 Feb 21. Epub 2019 Feb 21.

Department of Clinical Genetics, St George's University of London, London, United Kingdom.

Overgrowth-intellectual disability (OGID) syndromes are characterized by increased growth (height and/or head circumference ≥+2 SD) in association with an intellectual disability. Constitutive EED variants have previously been reported in five individuals with an OGID syndrome, eponymously designated Cohen-Gibson syndrome and resembling Weaver syndrome. Here, we report three additional individuals with constitutive EED variants, identified through exome sequencing of an OGID patient series. Read More

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http://dx.doi.org/10.1002/ajmg.a.61066DOI Listing
February 2019

Outcomes of very preterm infants with and without BPD followed to preschool age.

Pediatr Int 2019 Feb 22. Epub 2019 Feb 22.

Division of Neonatology, Department of Pediatrics and Adolescence Medicine, Medical University of Graz, Austria.

Background: Bronchopulmonary dysplasia (BPD) is the most frequent chronic lung disease in infancy and associated with neonatal comorbidities and impairments in pulmonary and neurodevelopmental (ND) long-term outcome.

Methods: Retrospective, single center, cohort study to compare a cohort of very preterm infants (gestational age (GA) 24 - 28 weeks) with BPD (n=44), with a cohort of GA matched preterms without BPD (n=44) concerning neonatal morbidities, incidence of lower respiratory tract infections (LRTIs), ND-outcome and growth to 2 years corrected age (CA) and preschool age.

Results: BPD (incidence 11. Read More

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http://dx.doi.org/10.1111/ped.13815DOI Listing
February 2019

Comparison of Bethesda cytopathology classification to surgical pathology across racial-ethnic groups.

Head Neck 2019 Feb 21. Epub 2019 Feb 21.

Department of Otorhinolaryngology-Head and Neck Surgery, Montefiore Medical Center/Albert Einstein College of Medicine, New York, New York.

Background: The Bethesda System standardized the reporting of thyroid cytopathology and created categories to provide an estimation of a nodule's risk of malignancy. There are limited data describing their utility in different racial-ethnic groups.

Methods: A retrospective chart review of thyroid fine-needle aspirations (FNA) was performed within our health-care systems. Read More

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http://dx.doi.org/10.1002/hed.25707DOI Listing
February 2019

Disruption of O-GlcNAc homeostasis during mammalian oocyte meiotic maturation impacts fertilization.

Mol Reprod Dev 2019 Feb 21. Epub 2019 Feb 21.

Department of Obstetrics and Gynecology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.

Meiotic maturation and fertilization are metabolically demanding processes, and thus the mammalian oocyte is highly susceptible to changes in nutrient availability. O-GlcNAcylation-the addition of a single sugar residue (O-linked β-N-acetylglucosamine) on proteins-is a posttranslational modification that acts as a cellular nutrient sensor and likely modulates the function of oocyte proteins. O-GlcNAcylation is mediated by O-GlcNAc transferase (OGT), which adds O-GlcNAc onto proteins, and O-GlcNAcase (OGA), which removes it. Read More

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http://dx.doi.org/10.1002/mrd.23131DOI Listing
February 2019
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