604,024 results match your criteria Head & Face Medicine [Journal]


Using Inertial Sensors to Quantify Postural Sway and Gait Performance during the Tandem Walking Test.

Sensors (Basel) 2019 Feb 13;19(4). Epub 2019 Feb 13.

Department of Otolaryngology Head and Neck Surgery, Laboratory of Vestibular Neuroadaptation, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.

Vestibular dysfunction typically manifests as postural instability and gait irregularities, in part due to inaccuracies in processing spatial afference. In this study, we have instrumented the tandem walking test with multiple inertial sensors to easily and precisely investigate novel variables that can distinguish abnormal postural and gait control in patients with unilateral vestibular hypofunction. Ten healthy adults and five patients with unilateral vestibular hypofunction were assessed with the tandem walking test during eyes open and eyes closed conditions. Read More

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http://dx.doi.org/10.3390/s19040751DOI Listing
February 2019

Chronic Rhinosinusitis: Does Allergy Play a Role?

Med Sci (Basel) 2019 Feb 18;7(2). Epub 2019 Feb 18.

Department of Otolaryngology-Head and Neck Surgery, Emory University, Atlanta, GA 30308, USA.

A few chronic rhinosinusitis (CRS) variants have demonstrated a strong association with environmental allergy, including allergic fungal rhinosinusitis (AFRS) and central compartment atopic disease (CCAD). However, the overall relationship between CRS and allergy remains poorly defined. The goal of this review is to evaluate the relationship between CRS and allergy with a focus on specific CRS variants. Read More

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http://dx.doi.org/10.3390/medsci7020030DOI Listing
February 2019

The Emerging Role of Robotic Surgery among Minimally Invasive Surgical Approaches in the Treatment of Hypopharyngeal Carcinoma: Systematic Review and Meta-Analysis.

J Clin Med 2019 Feb 18;8(2). Epub 2019 Feb 18.

Otorhinolaryngology Unit, Humanitas University, Humanitas Clinical and Research Center-IRCCS, 20089 Rozzano, Italy.

The aim of this systematic review with meta-analysis was to investigate the available literature on transoral approaches in the treatment of hypopharyngeal squamous cell carcinoma, with a special focus on transoral robotic surgery (TORS). A systematic review was conducted according to the PRISMA (preferred reporting items for systematic reviews and meta-analyses) check-list, and 15 studies were included. Five of the included studies evaluated TORS, while ten studies focused on transoral laser microsurgery (TLM) for the treatment of early or advanced stage hypopharyngeal cancer. Read More

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http://dx.doi.org/10.3390/jcm8020256DOI Listing
February 2019

Mortality Risk and Risk Factors in Patients with Posttraumatic Epilepsy: A Population-Based Cohort Study.

Int J Environ Res Public Health 2019 Feb 18;16(4). Epub 2019 Feb 18.

Graduate Institute of Biomedical Sciences and School of Medicine, College of Medicine, China Medical University, Taichung 404, Taiwan.

Use the National Health Insurance Research Database of Taiwan to determine whether patients with posttraumatic epilepsy (PTE) have an increased risk of mortality. Patients ≥20 years old ever admitted because of head injury (per International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) codes 850⁻854 and 959.01) during 2000⁻2012 were enrolled into a traumatic brain injury (TBI) cohort. Read More

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http://dx.doi.org/10.3390/ijerph16040589DOI Listing
February 2019

Enhanced Three Layer Hybrid Clustering Mechanism for Energy Efficient Routing in IoT.

Sensors (Basel) 2019 Feb 18;19(4). Epub 2019 Feb 18.

Department of Electrical Engineering, Bahria University, Islamabad 44000, Pakistan.

Recently, different routing techniques were proposed for three layer clustering topology in Wireless Sensor Network (WSN) which outperform the basic two layer clustering hierarchy. The problem that remains in these approaches is the heavy control packet exchange between nodes after every round in order to choose efficient lower layer heads. Among these techniques is Hybrid Hierarchical Clustering Approach (HHCA), in which a distributed approach is proposed. Read More

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http://dx.doi.org/10.3390/s19040829DOI Listing
February 2019

Infiltration of FoxP3+ Regulatory T Cells is a Strong and Independent Prognostic Factor in Head and Neck Squamous Cell Carcinoma.

Cancers (Basel) 2019 Feb 15;11(2). Epub 2019 Feb 15.

Department of Human Anatomy and Experimental Oncology, Faculty of Medicine and Pharmacy, University of Mons, 7000 Mons, Belgium.

Head and Neck Squamous Cell Carcinomas (HNSCC) are characterized by a large heterogeneity in terms of the location and risk factors. For a few years now, immunotherapy seems to be a promising approach in the treatment of these cancers, but a better understanding of the immune context could allow to offer a personalized treatment and thus probably increase the survival of HNSCC patients. In this context, we evaluated the infiltration of FoxP3+ Tregs on 205 human formalin-fixed paraffin-embedded HNSCC and we assessed its prognostic value compared to other potential prognostic factors, including HPV infection. Read More

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http://dx.doi.org/10.3390/cancers11020227DOI Listing
February 2019

Combining many-objective radiomics and 3-dimensional convolutional neural network through evidential reasoning to predict lymph node metastasis in head and neck cancer.

Phys Med Biol 2019 Feb 19. Epub 2019 Feb 19.

Department of Radiation Oncology, University of Texas Southwestern Medical Centre, 5801 Forest Park Road, Dallas, TX 75390-9183, Dallas, Texas, UNITED STATES.

Lymph node metastasis (LNM) is a significant prognostic factor in patients with head and neck cancer, and the ability to predict it accurately is essential to optimizing treatment. Positron emission tomography (PET) and computed tomography (CT) imaging are routinely used to identify LNM. Although large or highly active lymph nodes (LNs) have a high probability of being positive, identifying small or less reactive LNs is challenging. Read More

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http://dx.doi.org/10.1088/1361-6560/ab083aDOI Listing
February 2019

A cone-shaped gradient coil design for high-resolution MRI head imaging.

Phys Med Biol 2019 Feb 19. Epub 2019 Feb 19.

School of Information Technology and Electrical Engineering, University of Queensland, Brisbane, Queensland, AUSTRALIA.

Insertable head gradient coils offer significant advantages such as high gradient strength and fast gradient switching speed owing to close distance to the target region of interest than whole-body cylindrical coils. To produce superior gradient performance, the local head coil is typically designed with an asymmetric configuration to accommodate both the shoulders and head of a patient, leading to tough dimensional constraints and practical limits to the coil implementation. In this paper, we proposed a new cone-shaped model to improve the performance of the asymmetric head coils and also to mitigate patient claustrophobia. Read More

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http://dx.doi.org/10.1088/1361-6560/ab084aDOI Listing
February 2019

Immunotoxicity of estrogen and nonylphenol on apoptosis and expression of ERs in goldfish macrophage: Opening new avenue for discovering the role of experimental model systems and sexes.

Aquat Toxicol 2019 Feb 13;209:159-167. Epub 2019 Feb 13.

Department of Fisheries, Faculty of Marine Natural resources, Khorramshahr University of Marine Science and Technology, P.O. Box 669, Khorramshahr, Iran. Electronic address:

The expression of estrogen receptors (ERs) and their roles in important cell processes such as apoptosis in the macrophages exposed to estrogen/xenoestrogen have remained a complex secret. This study focused on the expression of estrogen receptors (ERs) and the stimulation of apoptosis in the macrophages from the two sexes of goldfish (Carassius auratus) exposed to 17-βestradiol (E2) and nonylphenol (NP) under in vivo and in vitro conditions. For the in vivo experiment, fish were exposed to NP (10 M and 10 M) and E2 (10 M) for 24 days. Read More

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http://dx.doi.org/10.1016/j.aquatox.2019.02.007DOI Listing
February 2019

PD-L1 expression, tumor mutational burden and cancer gene mutations are stronger predictors of benefit from immune checkpoint blockade than HLA class I genotype in non-small cell lung cancer.

J Thorac Oncol 2019 Feb 16. Epub 2019 Feb 16.

Department of Thoracic / Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Unit 0432, Houston, Texas, 77030, United States of America. Electronic address:

Introduction: Immune checkpoint blockade (ICB) has revolutionized the treatment of non-small cell lung cancer (NSCLC), but only ∼15% of patients achieve durable benefit. Understanding resistance mechanisms to ICB is pivotal in developing more effective treatment strategies. Recent studies showed human leukocyte antigen (HLA) class I heterozygosity might be important in mediating benefit from ICB. Read More

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http://dx.doi.org/10.1016/j.jtho.2019.02.008DOI Listing
February 2019

Effects of dietary dandelion extracts on growth performance, liver histology, immune-related gene expression and CCl resistance of hybrid grouper (Epinephelus lanceolatus♂ × Epinephelus fuscoguttatus♀).

Fish Shellfish Immunol 2019 Feb 16. Epub 2019 Feb 16.

Institute of Modern Aquaculture Science and Engineering, Guangzhou Key Laboratory of Subtropical Biodiversity and Biomonitoring, Guangdong Provincial Key Laboratory for Healthy and Safe Aquaculture, School of Life Science, South China Normal University, Guangzhou, 510631, PR China. Electronic address:

The study investigated the effects of dietary supplementation with dandelion extracts (DE) on growth performance, feed utilization, body composition, serum biochemical, liver histology, immune-related gene expression and CCl resistance of hybrid grouper (Epinephelus lanceolatus♂ × Epinephelus fuscoguttatus♀). A basal diet supplemented with DE at 0% (diet 0%), 0.1% (diet 0. Read More

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http://dx.doi.org/10.1016/j.fsi.2019.02.031DOI Listing
February 2019

Ultrasound and clinical features of hip involvement in patients with gout.

Joint Bone Spine 2019 Feb 16. Epub 2019 Feb 16.

Università Politecnica delle Marche, Clinica Reumatologica, Dipartimento di Scienze Cliniche e Molecolari, Ancona, 60126, Italy.

Objectives: To investigate the prevalence of the ultrasound findings indicative of monosodium urate crystal deposits at the hip joint in patients with gout and to explore the association between the ultrasound findings and the clinical and serological features.

Methods: Bilateral ultrasound assessment of the hip joint was carried out in 40 consecutive patients with gout, diagnosed according to the latest Gout American College of Rheumatology/European League Against Rheumatism classification criteria, and 25 disease controls. Ultrasound evidence of crystal deposits was obtained using the Outcome Measures in Rheumatology definitions: hip intra-articular aggregates and/or tophi, and "double contour" sign over the hyaline cartilage of the femoral head. Read More

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http://dx.doi.org/10.1016/j.jbspin.2019.01.027DOI Listing
February 2019

A 2-Year Prospective Study of Injury Epidemiology in Elite Australian Rugby Sevens: Exploration of Incidence Rates, Severity, Injury Type, and Subsequent Injury in Men and Women.

Am J Sports Med 2019 Feb 19:363546518825380. Epub 2019 Feb 19.

La Trobe Sport and Exercise Medicine Research Centre, La Trobe University, Bundoora, Australia.

Background:: Injuries are common in rugby sevens, but studies to date have been limited to short, noncontinuous periods and reporting of match injuries only.

Purpose:: To report the injury incidence rate (IIR), severity, and burden of injuries sustained by men and women in the Australian rugby sevens program and to provide the first longitudinal investigation of subsequent injury occurrence in rugby sevens looking beyond tournament injuries only.

Study Design:: Descriptive epidemiology study. Read More

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http://dx.doi.org/10.1177/0363546518825380DOI Listing
February 2019

Association of Periodontitis with Oral Cancer: A Case-Control Study.

J Dent Res 2019 Feb 19:22034519827565. Epub 2019 Feb 19.

1 Department of Preventive and Social Dentistry, School of Dentistry, Seoul National University, Seoul, Korea.

The association between oral squamous cell carcinoma (OSCC) and periodontitis in large hospital cases with cohort controls has yet to be evaluated. The aim of this study was to investigate the association of periodontitis with OSCC across tumor location and tumor-node-metastasis (TNM) stage among Koreans ( N = 424). OSCC cases ( n = 146) were recruited from Seoul National University Dental Hospital and matched by age, sex, and smoking to controls ( n = 278) from the Yangpyeong health and periodontal cohort in Korea. Read More

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http://dx.doi.org/10.1177/0022034519827565DOI Listing
February 2019

Prediction of lymph node metastasis in oral squamous cell carcinoma based on protein profile.

Expert Rev Proteomics 2019 Feb 19. Epub 2019 Feb 19.

a Department of Oral and Maxillofacial-Head & Neck Oncology, Shanghai Ninth People's Hospital & College of Stomatology , Shanghai Jiao Tong University School of Medicine ; Shanghai 200011 , China.

Objective: Lymph node metastasis leads to high mortality rates of oral squamous cell carcinoma (OSCC). However, it is still controversial to define clinically negative neck (cN0) and positive neck (cN1-3).

Methods: We retrieved candidate biomarkers identified by proteomic analysis in OSCC from published literatures. Read More

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http://dx.doi.org/10.1080/14789450.2019.1584039DOI Listing
February 2019

A high-fat diet aggravates osteonecrosis through a macrophage-derived IL-6 pathway.

Int Immunol 2019 Feb 19. Epub 2019 Feb 19.

Department of Orthopaedic Surgery, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.

Inflammation plays an important role in osteonecrosis. Obesity, a risk factor for osteonecrosis, leads to a chronic inflammatory status. We hypothesized that inflammation mediated the effects of obesity on osteonecrosis and tested our hypothesis in a mouse model of osteonecrosis. Read More

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http://dx.doi.org/10.1093/intimm/dxz002DOI Listing
February 2019

Preoperative difficult airway prediction using suprahyoid and infrahyoid ultrasonography derived measurements in anesthesiology.

Med Ultrason 2019 Feb;21(1):83-88

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Airway management is one of the most important skills in everyday practice of anesthesia. Improper airway management might contribute to significant morbidity and mortality. In some patients, clinical parameters do not anticipate all difficulties related to airway management. Read More

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http://dx.doi.org/10.11152/mu-1764DOI Listing
February 2019

Clinical management of localized undifferentiated sinonasal carcinoma: our experience and review of the literature.

Anticancer Drugs 2019 Mar;30(3):308-312

Departments of Head and Neck and Sarcoma Oncology.

Undifferentiated sinonasal carcinoma (SNUC) is defined as a small round blue cell tumor that is immunohistochemically distinct from other sinonasal malignancies, such as lymphoma, mucosal melanoma, nasopharyngeal carcinoma, neuroendocrine carcinoma, and olfactory neuroblastoma. SNUCs are very aggressive malignancies, provoking quick destruction of the splanchnocranium structures. Being a very rare neoplasm, there are no prospective clinical trials assessing their treatment strategies, so lots of data are derived by small retrospective trials. Read More

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http://dx.doi.org/10.1097/CAD.0000000000000707DOI Listing

Review of DNA tumour viruses.

Authors:
Aldo Venuti

Hum Vaccin Immunother 2019 Feb 19. Epub 2019 Feb 19.

a Head HPV Unit, UOSD Tumor Immunology and Immunotherapy , IRCCS Regina Elena National Cancer Institute , Rome , Italy ,

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http://dx.doi.org/10.1080/21645515.2019.1577677DOI Listing
February 2019

Epistaxis Risk Associated with Intranasal Corticosteroid Sprays: A Systematic Review and Meta-analysis.

Otolaryngol Head Neck Surg 2019 Feb 19:194599819832277. Epub 2019 Feb 19.

1 Department of Otolaryngology-Head and Neck Surgery, School of Medicine, Tulane University, New Orleans, Louisiana, USA.

Objective: Intranasal corticosteroids (INCSs) are widely utilized for the treatment of allergic rhinitis. Epistaxis is a known adverse effect of INCSs, but it is not known if the risk of epistaxis differs among INCSs.

Data Sources: Systematic review of primary studies identified through Medline, Embase, Web of Science, PubMed Central, and Cochrane databases. Read More

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http://dx.doi.org/10.1177/0194599819832277DOI Listing
February 2019

The relationship between 3D dentofacial photogrammetry measurements and traditional cephalometric measurements.

Angle Orthod 2019 Mar;89(2):275-283

Objectives:: To determine the relationship between traditional cephalometric measurements and corresponding nonradiographic three-dimensional (3D) photogrammetry measurements.

Materials And Methods:: This was a cross-sectional study of 20 orthodontic patients (10 male and 10 female) who received lateral cephalometric radiographs and 3D dentofacial photogrammetric records with each subject serving as his or her own control for a total sample size of 40 images (20 per method). A 3D analysis that resembled a traditional cephalometric analysis was established using the eyes and natural head orientation as substitutes for the cranial base. Read More

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http://dx.doi.org/10.2319/120317-825.1DOI Listing

Effects of spinal immobilization and spinal motion restriction on head-neck kinematics during ambulance transport.

Prehosp Emerg Care 2019 Feb 19:1-12. Epub 2019 Feb 19.

g University of Winnipeg , Gupta Faculty of Kinesiology and Applied Health , 515 Portage Avenue , Winnipeg , Manitoba , R3B 2E9 Canada.

Objective: To determine the influence of ambulance motion on head-neck (H-N) kinematics and to compare the effectiveness of two spinal precaution (SP) protocols: spinal immobilization (SI) and spinal motion reduction (SMR).

Methods: Eighteen healthy volunteers (7 females) underwent a series of standardized ambulance transport tasks, across various speeds, under the two SP protocols in a balanced order (n = 12 drivers, n = 7 ambulances). Inertial measurement units were placed on participants' heads and sternums, with another affixed to the stretcher mattress frame. Read More

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http://dx.doi.org/10.1080/10903127.2019.1584833DOI Listing
February 2019

Fine needle aspiration cytology and intraoperative frozen section in parotid gland tumor surgery: A retrospective multicenter analysis of 417 cases.

Clin Otolaryngol 2019 Feb 19. Epub 2019 Feb 19.

Department of Otorhinolaryngology and Head and Neck Surgery, Medical University of Vienna, Vienna, Austria.

Salivary gland tumors represent a group of heterogeneous lesions with distinct biological behavior and complex clinicopathological characteristics. In 70% of the cases the parotid gland is affected and in about 80% the tumor is benign. In general, an accurate diagnosis of parotid tumors consists of a triple assessment, comprising clinical examination, imaging and histological or cytological analysis. Read More

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http://dx.doi.org/10.1111/coa.13314DOI Listing
February 2019

Intraoperative electron beam radiotherapy for locoregionally persistent or recurrent head and neck cancer.

Head Neck 2019 Feb 19. Epub 2019 Feb 19.

Department of Radiation Oncology, Arthur G. James Comprehensive Cancer Center and Richard J. Solove Research Institute, The Ohio State University Medical Center, Columbus, Ohio.

Background: To report our institutional experience with intraoperative radiotherapy for persistent or recurrent head and neck cancer.

Methods: Sixty-one patients were treated with salvage surgery and intraoperative radiation therapy (IORT). Fifty-eight patients (95%) had previously received external beam radiotherapy (EBRT) as a component of their definitive therapy. Read More

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http://dx.doi.org/10.1002/hed.25673DOI Listing
February 2019

VOR adaptation training and retention in a patient with profound bilateral vestibular hypofunction.

Laryngoscope 2019 Feb 19. Epub 2019 Feb 19.

Laboratory of Vestibular NeuroAdaptation, Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, U.S.A.

A novel training method known as incremental VOR adaptation (IVA) can improve the vestibulo-ocular reflex (VOR) gain for both active and passive head rotation by coupling active head rotations with a laser-projected target that moves in the opposite direction of the head at a fraction of the head velocity. A 51-year-old male with bilateral vestibular hypofunction participated in a research protocol using a portable IVA device for 645 days. Passive VOR gains improved 179% to 600%; standing posture and gait also improved. Read More

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http://dx.doi.org/10.1002/lary.27838DOI Listing
February 2019

Radiotherapy for benign head and neck paragangliomas.

Head Neck 2019 Feb 19. Epub 2019 Feb 19.

Department of Otolaryngology, University of Florida College of Medicine, Gainesville, Florida.

Purpose: To update our experience treating benign head-and-neck paragangliomas (PGs) with radiotherapy (RT).

Methods: A total of 149 patients with 176 PGs received curative-intent RT; 126 received RT to 1 PG and 23 to 2 or more PGs. The most common dose fractionation schedule was 45 Gy/25 once-daily fractions/5 weeks which was used to treat 147 PGs (83. Read More

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http://dx.doi.org/10.1002/hed.25664DOI Listing
February 2019

Staging soft tissue sarcoma of the head and neck: Evaluation of the AJCC 8th edition revised T classifications.

Authors:
Justin M M Cates

Head Neck 2019 Feb 19. Epub 2019 Feb 19.

Department of Pathology, Microbiology and Immunology, Division of Anatomic Pathology, Vanderbilt University Medical Center, Nashville, Tennessee.

Background: The American Joint Committee on Cancer (AJCC) has proposed new T classifications for head and neck sarcomas in the 8th edition of the AJCC Cancer Staging Manual, but these classifications have not been evaluated for prognostic utility in tumor staging.

Methods: The predictive ability of revised AJCC T classifications was evaluated by nonlinear multivariable regression using records from the Surveillance, Epidemiology, and End Results database (N = 2756). A proposed staging algorithm was developed using a subset of records and compared to the AJCC 7th edition using a separate validation dataset. Read More

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http://dx.doi.org/10.1002/hed.25701DOI Listing
February 2019

Hypopharyngeal cancer treatment: Does initial surgery confer survival benefit?

Head Neck 2019 Feb 19. Epub 2019 Feb 19.

Department of Otolaryngology and Immunology, University of Pittsburgh Medical Center and Cancer Institute, Pittsburgh, Pennsylvania.

Background: Organ preservation protocols have increasingly been applied for the treatment of head and neck cancers, including hypopharyngeal squamous cell carcinoma (HSCC). We sought to evaluate whether patients treated with primary surgery followed by adjuvant therapy had survival benefit over patients treated with initial nonsurgical modalities.

Methods: We retrospectively reviewed patients with new diagnosis of HSCC at the University of Pittsburgh (1994-2014) treated with either primary total laryngectomy with pharyngectomy or organ preservation. Read More

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http://dx.doi.org/10.1002/hed.25687DOI Listing
February 2019

Cancer-related financial hardship among head and neck cancer survivors: risk factors and associations with health-related quality-of-life.

Psychooncology 2019 Feb 19. Epub 2019 Feb 19.

Institute of Health & Society, Newcastle University.

Objective: Cancer survivors are susceptible to financial hardship. In head and neck (HNC) survivors, we investigated (i) predictors for cancer-related financial hardship and (ii) associations between financial hardship and health-related quality-of-life (HRQoL).

Methods: We conducted a cross-sectional study in HNC survivors identified from the National Cancer Registry Ireland. Read More

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http://dx.doi.org/10.1002/pon.5034DOI Listing
February 2019

Establishment of a large animal model for Eustachian tube functional study in miniature pigs.

Anat Rec (Hoboken) 2019 Feb 18. Epub 2019 Feb 18.

Department of Otolaryngology & Head Neck Surgery, Chinese PLA General Hospital, Beijing, China.

Objectives: This study was performed to investigate whether miniature pigs are a suitable animal model for studies of the Eustachian tube (ET).

Methods: Sixteen Chinese experimental miniature pigs were used in this investigation. Ten animals were used for anatomical and morphometric analyses to obtain qualitative and quantitative information regarding the ET. Read More

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http://dx.doi.org/10.1002/ar.24098DOI Listing
February 2019

Recent historic perspective on modified neck dissection.

Authors:
Ashok R Shaha

Head Neck 2019 Feb 18. Epub 2019 Feb 18.

Department of Surgery, Head and Neck Service, Memorial Sloan Kettering Cancer Center, New York, NY.

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http://dx.doi.org/10.1002/hed.25700DOI Listing
February 2019

Thyroid cancer clinical trials in the United States: Understanding trends to maximize impact.

Head Neck 2019 Feb 18. Epub 2019 Feb 18.

Departments of Otolaryngology-Head and Neck Surgery, Neurologic Surgery, and Ophthalmology, Boston Medical Center, Boston, Massachusetts.

Background: We sought to understand thyroid cancer study modalities, publications, and grants. This provides scope, resources, and dissemination patterns to inform future directions for research and policy.

Methods: A retrospective study of thyroid cancer trials using ClinicalTrials. Read More

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http://dx.doi.org/10.1002/hed.25703DOI Listing
February 2019

Clinicopathological findings and clinical outcomes in 49 cases of feline pemphigus foliaceus examined in Northern California, USA (1987-2017).

Vet Dermatol 2019 Feb 18. Epub 2019 Feb 18.

Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, One Shields Avenue, Davis, CA, 95616, USA.

Background: Few studies have described the pathophysiology, clinical course, treatment outcomes and quality of life (QoL) of cats with pemphigus foliaceus (PF).

Objective: Describe clinicopathological features, treatment outcomes and impacts on QoL in feline PF.

Animals: Forty-nine client-owned cats with PF that presented to a veterinary teaching hospital between 1987 and 2017. Read More

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http://dx.doi.org/10.1111/vde.12731DOI Listing
February 2019

Role of phase angle in the evaluation of effect of an immuno-enhanced formula in post-surgical cancer patients: a randomized clinical trial.

Eur Rev Med Pharmacol Sci 2019 Feb;23(3):1322-1334

Section of Clinical Nutrition and Nutrigenomic, Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy.

Objective: Neoplastic disease is frequently associated with poor nutritional status or severe malnutrition. Diet and nutritional intervention are becoming increasingly important for prognosis and quality of life in cancer patients. Accessible and repeatable tools for assessing nutritional status with body composition techniques seems to be fundamental. Read More

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http://dx.doi.org/10.26355/eurrev_201902_17027DOI Listing
February 2019

SP1-induced upregulation of long noncoding RNA LINC00313 contributes to papillary thyroid cancer progression via the miR-422a.

Eur Rev Med Pharmacol Sci 2019 Feb;23(3):1134-1144

Department of Head and Neck Surgery, National Cancer Center/ National Clinical Research Center for Cancer/ Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union.

Objective: Long noncoding RNA LINC00313 (LINC00313) has been reported to be dysregulated in several tumors, including papillary thyroid carcinoma (PTC). Our present study aimed to further explore the potential mechanism of LINC00313 in the progression of papillary thyroid carcinoma (PTC).

Patients And Methods: RT-PCR was performed to detect the expression of LINC00313 in both PTC tissues and cell lines. Read More

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http://www.europeanreview.org/article/17004
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http://dx.doi.org/10.26355/eurrev_201902_17004DOI Listing
February 2019
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Treatment of sleep-disordered breathing with positional therapy: long-term results.

Sleep Breath 2019 Feb 18. Epub 2019 Feb 18.

Department of Otorhinolaryngology, Head and Neck Surgery, Antwerp University Hospital, Wilrijkstraat 10, 2650, Edegem, Belgium.

Purpose: The aim of the present study was to assess the efficacy of a sleep position trainer (SPT) in patients with an established diagnosis of positional obstructive sleep apnea and to evaluate the adherence after 1-year follow-up.

Methods: Polysomnography (PSG) was performed at baseline and after 1 year of SPT use. Patients received questionnaires to assess treatment satisfaction and subjective adherence. Read More

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http://dx.doi.org/10.1007/s11325-019-01792-9DOI Listing
February 2019

CARING: The Impact of a Parent-Child, Play-Based Intervention to Promote Latino Head Start Children's Social-Emotional Development.

J Prim Prev 2019 Feb 18. Epub 2019 Feb 18.

Hofstra University, Hempstead, NY, USA.

CARING is a preventive, play-based, parent-child intervention designed to promote preschoolers' social-emotional development by strengthening their bonds with their parents. We describe the qualitative impact of the CARING Preschool program on Latino preschool children and their parents. One hundred and eleven Latino families participated in a larger study of the efficacy of the CARING preschool program. Read More

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http://dx.doi.org/10.1007/s10935-019-00542-7DOI Listing
February 2019

Cerebrolysin as a New Treatment Option for Post-Stroke Spasticity: Patient and Physician Perspectives.

Neurol Ther 2019 Feb 18. Epub 2019 Feb 18.

, Kiev, Ukraine.

Introduction: Recent studies show that spasticity occurs in 20-30% of all stroke victims, especially in younger patients. Botulinum toxin is a very effective treatment; however, it is not reimbursed in the Ukraine, thus leaving patients untreated and unable to use the paralyzed limb. Finally, this might result in long-term disability with economic consequences and negative impact on the psychological state of patients. Read More

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http://dx.doi.org/10.1007/s40120-019-0128-1DOI Listing
February 2019

Measurement properties of instruments for assessment of cervical spine function in infants with torticollis: a systematic review.

Eur J Pediatr 2019 Feb 18. Epub 2019 Feb 18.

Department of Physiotherapy, Trinity College, Dublin University, Dublin 2, Ireland.

The aim of this study was to systematically review the measurement properties of instruments which assess cervical spine function in infants with torticollis. Electronic searches were performed in MEDLINE, CINAHL, Embase, Web of Science and the Cochrane Library, combining three constructs ('torticollis', 'cervical spine assessment' and 'measurement properties'). Two reviewers independently rated the methodological quality and the quality of measurement properties of identified articles, using both the COSMIN (COnsensus-based Standards for the selection of health status Measurement INstruments) checklist and quality criteria for measurement properties. Read More

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http://dx.doi.org/10.1007/s00431-019-03338-3DOI Listing
February 2019

Indications for tracheostomy in children with head and neck lymphatic malformation: analysis of a nationwide survey in Japan.

Surg Today 2019 Feb 18. Epub 2019 Feb 18.

Department of Pediatric Surgery, Osaka Women's and Children's Hospital, 840, Murodocho, Izumi, Osaka, Japan.

Purpose: Airway obstruction caused by lymphatic malformation (LM) in the head and neck may require a tracheostomy. We present the results of our analysis of a nationwide survey on the indications for tracheostomy in children with head and neck LM.

Methods: We analyzed data in relation to tracheostomy based on a questionnaire about 518 children with head and neck LM without mediastinal involvement. Read More

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http://dx.doi.org/10.1007/s00595-018-1755-3DOI Listing
February 2019

Parcellation of motor cortex-associated regions in the human corpus callosum on the basis of Human Connectome Project data.

Brain Struct Funct 2019 Feb 18. Epub 2019 Feb 18.

Functional Imaging Unit, Institute of Diagnostic Radiology and Neuroradiology, University Medicine Greifswald, Walther- Rathenau-Str. 46, 17475, Greifswald, Germany.

The corpus callosum (CC) is the largest white matter structure of the brain and offers the structural basis for an intense interaction between both cerebral hemispheres. Especially with respect to the interaction of both motor cortices it shows a differentiated somatotopic organization. Neuropathological processes are often reflected in structural alterations of the CC and a spatially precise description of structures for the healthy brain is essential for further differentiation of structural damage in patients. Read More

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http://dx.doi.org/10.1007/s00429-019-01849-1DOI Listing
February 2019

Lymphomas of the head and neck region: an update.

Virchows Arch 2019 Feb 18. Epub 2019 Feb 18.

International Head and Neck Scientific Group, Padua, Italy.

The field of haematopathology is rapidly evolving and for the non-specialized pathologist receiving a specimen with the possibility of a lymphoid malignancy may be a daunting experience. The coincidence of the publication, in 2017, of the WHO monographies on head and neck and haematopoietic and lymphoid tumours prompted us to write this review. Although not substantially different from lymphomas elsewhere, lymphomas presenting in this region pose some specific problems and these are central to the review. Read More

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http://dx.doi.org/10.1007/s00428-019-02543-7DOI Listing
February 2019

Exploring molecular tools for transformation and gene expression in the cultivated edible mushroom Agrocybe aegerita.

Mol Genet Genomics 2019 Feb 18. Epub 2019 Feb 18.

Junior Research Group Genetics and Genomics of Fungi, Senckenberg Biodiversity and Climate Research Centre (SBiK-F), Senckenberganlage 25, 60325, Frankfurt am Main, Germany.

Agrocybe aegerita is a cultivated edible mushroom in numerous countries, which also serves as a model basidiomycete to study fruiting body formation. Aiming to create an easily expandable customised molecular toolset for transformation and constitutive gene of interest expression, we first created a homologous dominant marker for transformant selection. Progeny monokaryons of the genome-sequenced dikaryon A. Read More

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http://dx.doi.org/10.1007/s00438-018-01528-6DOI Listing
February 2019

Unusual and multiple variations of head and neck veins: a case report.

Surg Radiol Anat 2019 Feb 18. Epub 2019 Feb 18.

Department of Anatomy, JIPMER, Puducherry, India.

We report an unusual and multiple variation involving the right head and neck veins which were found during routine dissection in a 50-year-old male cadaver, facial vein draining into both external and internal jugular veins, fenestration in external jugular vein transmitting the supraclavicular nerve trunk, the anterior division of the retromandibular vein draining into anterior jugular vein and the absence of the common facial vein. The knowledge about these variations is important during various surgical and diagnostic procedures involving head and neck region. Read More

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http://dx.doi.org/10.1007/s00276-019-02203-0DOI Listing
February 2019

Anatomic variations of the paranasal sinuses in the general pediatric population.

Rhinology 2019 Feb 19. Epub 2019 Feb 19.

Department of Otolaryngology, Head and Neck Surgery, Kaplan Medical Center, Rehovot, Israel.

Background: The prevalence of sinuses' anatomic variations in the healthy pediatric population has not been studied. The study describes the prevalence of known anatomic variations with regard to gender and age in this population.

Methods: A single academic institute observational cohort study. Read More

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http://dx.doi.org/10.4193/Rhin18.193DOI Listing
February 2019

[Kleine Levin syndrome: Review of diagnosed cases of Buenos Aires, Argentina].

Vertex 2018 May;XXIX(139):165-171

Sección de Medicina del sueño. Neurología. Hospital Italiano. Hospital Británico. Buenos Aires.

Kleine-Levin syndrome is an uncommon disorder with recurrent episodes of hypersomnia, and behavioral abnormalities such as binge-eating and hypersexuality. Our aims were to report cases of the Kleine-Levin syndrome diagnosed in Buenos Aires, Argentina and to characterize the clinical presentation of these patients. We evaluated patients with Kleine-Levin syndrome according to the International Classification of Sleep Disorders. Read More

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Eotaxin-3 as a Plasma Biomarker for Mucosal Eosinophil Infiltration in Chronic Rhinosinusitis.

Front Immunol 2019 4;10:74. Epub 2019 Feb 4.

Department of Otorhinolaryngology, Head and Neck Surgery, Graduate School of Medicine, Akita University, Akita, Japan.

Chronic rhinosinusitis with nasal polyps exhibits marked eosinophilic infiltration and its mucosal eosinophilia is associated with more severe symptoms. The Japanese epidemiological survey of refractory eosinophilic chronic rhinosinusitis found that patients with nasal polyps required multiple surgeries when there were higher infiltrating eosinophils in the mucosa. In order to identify plasma biomarkers for local eosinophil infiltration in rhinosinusitis for surgery, we examined the levels of molecules in the plasma of patients and compared the number of infiltrating eosinophils in the nasal mucosa. Read More

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http://dx.doi.org/10.3389/fimmu.2019.00074DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369170PMC
February 2019

Three-Dimensional Magnetic Resonance Imaging Reveals the Relationship Between the Control of Vertigo and Decreases in Endolymphatic Hydrops After Endolymphatic Sac Drainage With Steroids for Meniere's Disease.

Front Neurol 2019 4;10:46. Epub 2019 Feb 4.

Department of Otolaryngology- Head and Neck Surgery, Nara Medical University, Kashihara, Japan.

Meniere's disease is a common disease, that presents with recurrent vertigo and cochlear symptoms. The pathology of Meniere's disease was first reported to involve endolymphatic hydrops in 1938. The endolymphatic sac is thought to have a role to keep the hydrostatic pressure and endolymph homeostasis for the inner ear. Read More

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http://dx.doi.org/10.3389/fneur.2019.00046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369164PMC
February 2019

Polypeptide Nanogels With Different Functional Cores Promote Chemotherapy of Lung Carcinoma.

Front Pharmacol 2019 4;10:37. Epub 2019 Feb 4.

Department of Geriatrics, The First Hospital of Jilin University, Changchun, China.

Two kinds of tumor microenvironment-responsive polypeptide nanogels were developed for intracellular delivery of cytotoxics to enhance the antitumor efficacies and reduce the side effects in the chemotherapy of lung carcinoma. The sizes of both doxorubicin (DOX)-loaded nanogels methoxy poly(ethylene glycol)-poly(L-phenylalanine--L-cystine) [mPEG-P(LP--LC)] and methoxy poly(ethylene glycol)-poly(L-glutamic acid--L-cystine) [mPEG-P(LG--LC)] (NGP/DOX and NGG/DOX) were less than 100 nm, which was appropriate for the enhanced permeability and retention (EPR) effect. The bigger and smaller scale of nanoparticle could induce the elimination of reticuloendothelial system (RES) and decrease the circulating half-life, respectively. Read More

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http://dx.doi.org/10.3389/fphar.2019.00037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369202PMC
February 2019
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