494 results match your criteria Hand Injury High Pressure


Imbalance in Renal Vasoactive Enzymes Induced by Mild Hypoxia: Angiotensin-Converting Enzyme Increases While Neutral Endopeptidase Decreases.

Front Physiol 2018 11;9:1791. Epub 2018 Dec 11.

Laboratorio de Neurobiología, Department of Physiology, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile, Santiago, Chile.

Chronic hypoxia has been postulated as one of the mechanisms involved in salt-sensitive hypertension and chronic kidney disease (CKD). Kidneys have a critical role in the regulation of arterial blood pressure through vasoactive systems, such as the renin-angiotensin and the kallikrein-kinin systems, with the angiotensin-converting enzyme (ACE) and kallikrein being two of the main enzymes that produce angiotensin II and bradykinin, respectively. Neutral endopeptidase 24. Read More

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http://dx.doi.org/10.3389/fphys.2018.01791DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297360PMC
December 2018
1 Read

Tachycardia after acute deceleration injury.

Heart 2018 Nov 15. Epub 2018 Nov 15.

Departments of Cardiology and Cardiac Surgery, University Hospital of Wales, Cardiff, UK.

A 29-year-old man crashed at high speed into another vehicle at traffic lights. He was able to get out of his van but then collapsed after running a few metres. On arrival in the emergency department he was conscious, with a pulse of 140 beats/min and blood pressure of 110/32 mm Hg. Read More

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http://dx.doi.org/10.1136/heartjnl-2018-314082DOI Listing
November 2018
1 Read

Effects of lumbo-pelvic rhythm on trunk muscle forces and disc loads during forward flexion: A combined musculoskeletal and finite element simulation study.

J Biomech 2019 Jan 25;82:116-123. Epub 2018 Oct 25.

Department of Mechanical Engineering, Khalifa University, Abu Dhabi, United Arab Emirates. Electronic address:

Previous in-vivo studies suggest that the ratio of total lumbar rotation over pelvic rotation (lumbo-pelvic rhythm) during trunk sagittal movement is essential to evaluate spinal loads and discriminate between low back pain and asymptomatic population. Similarly, there is also evidence that the lumbo-pelvic rhythm is key for evaluation of realistic muscle and joint reaction forces and moments predicted by various computational musculoskeletal models. This study investigated the effects of three lumbo-pelvic rhythms defined based on in-vivo measurements on the spinal response during moderate forward flexion (60°) using a combined approach of musculoskeletal modeling of the upper body and finite element model of the lumbosacral spine. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00219290183077
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http://dx.doi.org/10.1016/j.jbiomech.2018.10.009DOI Listing
January 2019
2 Reads
2.751 Impact Factor

Extract and Aucubin Prevent Desiccating Stress-Induced Corneal Epithelial Cell Injury and Improve Tear Secretion in a Mouse Model of Dry Eye Disease.

Molecules 2018 Oct 11;23(10). Epub 2018 Oct 11.

College Department of Oral Pathology, School of Dentistry, Chonbuk National University, Jeonju 54896, Korea.

Dry eye disease is affected by a broad range of causes such as age, lifestyle, environment, medication and autoimmune diseases. These causes induce tear instability that activates immune cells and promotes expression of inflammatory molecules. In this study, we investigated the therapeutic effects of an ethanolic extract of (AJE) and its bioactive compound, aucubin, on dry eye disease. Read More

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http://www.mdpi.com/1420-3049/23/10/2599
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http://dx.doi.org/10.3390/molecules23102599DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222834PMC
October 2018
1 Read

[High-pressure injection of paint into the hand: a severe injury that should not be underestimated].

An Sist Sanit Navar 2018 Dec 26;41(3):387-392. Epub 2018 Dec 26.

Complejo Hospitalario Universitario de Vigo (Pontevedra).

High-pressure injection into the hand causes a small skin lesion but severe subcutaneous tissue damage, which can result in permanent functional loss or amputation. Urgent and appropriate treatment is decisive. We present the case of an industrial painter who injected oil-based paint with a high-pressure gun into his left index finger. Read More

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http://dx.doi.org/10.23938/ASSN.0334DOI Listing
December 2018
3 Reads

Pulmonary effects of remote ischemic preconditioning in a porcine model of ventilation-induced lung injury.

Respir Physiol Neurobiol 2019 Jan 31;259:111-118. Epub 2018 Aug 31.

Department of Anesthesiology and Intensive Care Medicine, Otto-von-Guericke-University Magdeburg, Germany.

Background: One-lung ventilation (OLV) may result in lung injury due to increased mechanical stress and tidal recruitment. As a result, a pulmonary inflammatory response is induced. The present randomized, controlled, animal experiment was undertaken to assess the effects of remote ischemic preconditioning (RIP) on diffuse alveolar damage and immune response after OLV. Read More

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http://dx.doi.org/10.1016/j.resp.2018.08.009DOI Listing
January 2019

The entity of thermal-crush-avulsion hand injury (hot-press roller burns) treated with fast acting debriding enzymes (nexobrid): literature review and report of first case.

Ann Burns Fire Disasters 2018 Mar;31(1):31

Department of Plastic Surgery and Burn Centre, University Hospital of Parma, Italy.

Hand burns are present in >60% of all burn cases and in fire mass casualty incidents even up to 100%. Most trauma and especially burns may be detrimental to the complex and delicate structures of the hand by direct injury, indirect BICS (Burn Induced Compartment Syndrome and interstitial high pressure) or by delayed or faulty treatment. BICS represents a special threat as the increasing swelling and oedema of the small diameter hand and forearm will exert pressure on the capillary/venous system, eventually ending in irreversible damage to the skin, nerves, muscle and vascular bed. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116640PMC

Acute effects of different resistance training loads on cardiac autonomic modulation in hypertensive postmenopausal women.

J Transl Med 2018 Aug 30;16(1):240. Epub 2018 Aug 30.

Programa de Pós Graduação em Ciência da Saúde, Universidade Federal de Goiás, Goiânia, Brazil.

Background: Individuals with arterial hypertension often have an autonomic nervous system (ANS) imbalance with predominance of sympathetic ANS. This predominance can lead to injury of several organs affecting its functioning. There is evidence that performing high intensity resistance training (RT) with heavier loads and a lower number of repetitions results in lower cardiovascular stress when compared with lighter loads and a higher number of repetitions. Read More

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http://dx.doi.org/10.1186/s12967-018-1615-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117915PMC
August 2018
1 Read
3.930 Impact Factor

Physeal fracture in the wrist and hand due to stress injury in a child climber: A case report.

Medicine (Baltimore) 2018 Aug;97(34):e11571

Department of Orthopaedic Surgery, Soonchunhyang University Hospital, Cheonan.

Rationale: In competitive athletes, the upper extremity is subject to tremendous torsional forces with axial loading due to repetitive weight bearing. Approximately 25% of injuries in sports are related to the hand or wrist. Skeletal deformity on the wrist physis is common in athletes due to repetitive loading and presents at early ages between 6 and 13 years. Read More

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http://dx.doi.org/10.1097/MD.0000000000011571DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6112917PMC
August 2018
1 Read

High-pressure injection injury of the hand: peculiar MRI features and treatment implications.

Skeletal Radiol 2018 Jun 16. Epub 2018 Jun 16.

Department of Orthopedic Surgery, Mayo Clinic, 200 1st Street SW, Rochester, MN, 55905, USA.

High-pressure injection injuries of the hand are rare, but potentially devastating injuries. The amount of tissue damage is dependent on the magnitude of the pressure generated by the device and the composition of the injected material. The standard of care is emergent surgical debridement of the injected material and devitalized tissue. Read More

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http://dx.doi.org/10.1007/s00256-018-3005-6DOI Listing
June 2018
3 Reads

The effectiveness of a standard drill connected to a core biopsy needle: How to obtain specimens in very strong bone tumors.

Injury 2018 Aug 9;49(8):1612-1616. Epub 2018 Jun 9.

Oncological Orthopaedics Department, Regina Elena National Cancer Institute, Via Elio Chianesi no 53, 00144 Rome, Italy.

Introduction: Core biopsy is today recognized as the gold standard for the diagnosis of bone lesions; unfortunately, when the bone is too solid it can be very difficult to penetrate it; in case of failure, open biopsy is indicated but it is associated with greater contamination and complications. A possible solution is to connect a common orthopedic drill to the core biopsy needle. The aim of the presenting study was to present a technique useful for performing biopsies in case of very strong bone lesions and to evaluate the adequacy and quality of the obtained specimen. Read More

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http://dx.doi.org/10.1016/j.injury.2018.05.025DOI Listing

MRI and Neuropsychological Correlates in African Americans With Hypertension and Left Ventricular Hypertrophy.

Am J Hypertens 2018 Jul;31(8):865-868

Department of Emergency Medicine and Integrative Biosciences Center, Wayne State University, Detroit, Michigan, USA.

Background: African Americans (AAs) are at high risk for hypertension (HTN) and poor blood pressure (BP) control. Persistently elevated BP contributes to cardiovascular morbidity. White matter hyperintensities (WMHs) are a definable magnetic resonance imaging (MRI) marker of cerebrovascular injury linked to impairments in higher level thinking (i. Read More

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http://dx.doi.org/10.1093/ajh/hpy060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6049020PMC
July 2018
2 Reads

Case-control study on individual risk factors of carpal tunnel syndrome.

Exp Ther Med 2018 Mar 31;15(3):2761-2766. Epub 2018 Jan 31.

Department of Hand Surgery, Huashan Hospital, Fudan University, Shanghai 200040, P.R. China.

This study was conducted to observe the characteristics of the risk factors of carpal tunnel syndrome (CTS) in Chinese population. CTS of 1,512 outpatients aged 41-70 years were without any other diseases which could cause numbness as a case group, and 4,536 non-CTS outpatients as a control group were involved in the study in 2013-2014. Both groups received a questionnaire and the case group received another electrical physiological examination. Read More

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http://www.spandidos-publications.com/10.3892/etm.2018.5817
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http://dx.doi.org/10.3892/etm.2018.5817DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867472PMC
March 2018
5 Reads

Treatment of an Uncommon High-Pressure Orbital Injection Injury.

J Craniofac Surg 2018 Oct;29(7):1829-1831

Michigan State University College of Human Medicine.

Injection injuries occur most commonly in the hand and digits; however, there are a limited number of reports in the literature describing injection injuries involving the orbit. High-pressure orbital injection injuries pose a number of unique challenges to the treating physician, and the approach to treating these injuries remains controversial. Often times, the extent of tissue damage is not fully appreciated at presentation, which may lead to missed diagnoses or inadequate initial treatment. Read More

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http://dx.doi.org/10.1097/SCS.0000000000004521DOI Listing
October 2018
3 Reads

The open abdomen in trauma and non-trauma patients: WSES guidelines.

World J Emerg Surg 2018 2;13. Epub 2018 Feb 2.

Emergency and Trauma Surgery, Parma Maggiore Hospital, Parma, Italy.

Damage control resuscitation may lead to postoperative intra-abdominal hypertension or abdominal compartment syndrome. These conditions may result in a vicious, self-perpetuating cycle leading to severe physiologic derangements and multiorgan failure unless interrupted by abdominal (surgical or other) decompression. Further, in some clinical situations, the abdomen cannot be closed due to the visceral edema, the inability to control the compelling source of infection or the necessity to re-explore (as a "planned second-look" laparotomy) or complete previously initiated damage control procedures or in cases of abdominal wall disruption. Read More

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http://dx.doi.org/10.1186/s13017-018-0167-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797335PMC
September 2018
32 Reads

High-Pressure Water Injection Injuries of the Hand May Not Be Trivial.

Orthopedics 2018 Mar 29;41(2):e245-e251. Epub 2018 Jan 29.

High-pressure water injection injuries of the hand are uncommon, and there is limited literature to guide their treatment. The ideal management of these injuries, whether nonoperative with close observation or early surgical debridement, remains unknown. The authors retrospectively identified a cohort of patients with high-pressure water injection injuries to the hand during a 16-year period. Read More

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http://dx.doi.org/10.3928/01477447-20180123-04DOI Listing
March 2018
7 Reads

Abdominal Manual Therapy Repairs Interstitial Cells of Cajal and Increases Colonic c-Kit Expression When Treating Bowel Dysfunction after Spinal Cord Injury.

Biomed Res Int 2017 16;2017:1492327. Epub 2017 Nov 16.

The Second Clinical College, Nanjing University of Chinese Medicine, Nanjing, Jiangsu 210000, China.

Background: This study aimed to evaluate the therapeutic effects of abdominal manual therapy (AMT) on bowel dysfunction after spinal cord injury (SCI), investigating interstitial cells of Cajal (ICCs) and related c-kit expression.

Methods: Model rats were divided as SCI and SCI with drug treatment (intragastric mosapride), low-intensity (SCI + LMT; 50 g, 50 times/min), and high-intensity AMT (SCI + HMT; 100 g, 150 times/min). After 14 days of treatment, weight, improved Basso-Beattie-Bresnahan (BBB) locomotor score, and intestinal movement were evaluated. Read More

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http://dx.doi.org/10.1155/2017/1492327DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733934PMC
August 2018
7 Reads

Shoulder Functional Electrical Stimulation During Wheelchair Propulsion in Spinal Cord Injury Subjects.

Top Spinal Cord Inj Rehabil 2017 ;23(2):168-173

Department of Rehabilitation Medicine, FLENI Rehabilitation Institute, Buenos Aires, Argentina.

Subjects with spinal cord injury (SCI) propel their wheelchairs by generating a different level of muscle activity given their multiple deficits in muscle strength. Exercise training programs seem to be effective in improving wheelchair propulsion capacity. Functional electrical stimulation (FES) therapy is a complementary tool for rehabilitation programs. Read More

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http://dx.doi.org/10.1310/sci2302-168DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5672884PMC
August 2018
11 Reads

Evaluation of a functional hand orthosis combined with electrical stimulation adjunct to arm-hand rehabilitation in subacute stroke patients with a severely to moderately affected hand function.

Disabil Rehabil 2018 Jan 9:1-9. Epub 2018 Jan 9.

b Adelante Centre of Expertise in Rehabilitation and Audiology , Hoensbroek , the Netherlands.

Purpose: To investigate the usability and effectiveness of a functional hand orthosis, combined with electrical stimulation adjunct to therapy-as-usual, on functional use of the moderately/severely impaired hand in sub-acute stroke patients.

Materials And Methods: Single case experiment (A-B-A'-design) involving eight sub-acute stroke patients. The functional hand orthosis and electrical stimulation were used for six weeks, four days/week, 45'/day. Read More

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http://dx.doi.org/10.1080/09638288.2017.1423400DOI Listing
January 2018
7 Reads

Cold pressor test in spinal cord injury-revisited.

Spinal Cord 2018 06 20;56(6):528-537. Epub 2017 Dec 20.

International Collaboration on Repair Discoveries (ICORD), Blusson Spinal Cord Centre (BSCC), University of British Columbia, Vancouver, BC, Canada.

Study Design: Systematic review.

Objectives: A spinal cord injury (SCI) commonly results in alterations of cardiovascular physiology. In order to investigate such alterations, the cold pressor test (CPT) has been used as an established challenge test. Read More

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http://dx.doi.org/10.1038/s41393-017-0037-zDOI Listing
June 2018
8 Reads

High-Pressure Injection Injury Caused by Electronic Cigarette Explosion: A Case Report.

JBJS Case Connect 2017 Apr-Jun;7(2):e36

University of California San Diego, San Diego, California.

Case: Electronic cigarettes are an increasingly popular and poorly regulated alternative to traditional cigarettes that deliver nicotine and other aerosolized substances to the user via a battery-powered atomizer. We report a case in which an electronic cigarette explosion resulted in a high-pressure injection injury of the finger.

Conclusion: Explosions involving electronic cigarettes and similar handheld products should be treated as high-pressure injection injuries until proven otherwise. Read More

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http://dx.doi.org/10.2106/JBJS.CC.16.00177DOI Listing
August 2018
2 Reads

Ingestion of Coffee Polyphenols Improves a Scaly Skin Surface and the Recovery Rate of Skin Temperature after Cold Stress: A Randomized, Controlled Trial.

J Nutr Sci Vitaminol (Tokyo) 2017 ;63(5):291-297

Skin Care Products Research, Kao Corporation.

Coffee polyphenols (CPPs) derived from coffee beans have beneficial effects on blood pressure and vascular endothelial function. In addition, CPPs suppress ultraviolet light induced erythema. However, the effects of CPPs on dry skin and cutaneous vascular function have not been clarified. Read More

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http://dx.doi.org/10.3177/jnsv.63.291DOI Listing
July 2018
3 Reads

NOVEL CASE OF CLOSTRIDIUM PERFRINGENS ENDOPHTHALMITIS AFTER ANTI-VASCULAR ENDOTHELIAL GROWTH FACTOR INJECTION.

Retin Cases Brief Rep 2017 Nov 22. Epub 2017 Nov 22.

Ophthalmology Department, Kettering General Hospital, Kettering, United Kingdom.

Introduction: Endophthalmitis after anti-vascular endothelial growth factor injection is a rare complication but may lead to rapid destruction of structures within the eye. Infection with Clostridium perfringens has not previously been reported in this context.

Case Report: A 90-year-old woman presented with endophthalmitis of the right eye, 2 days after an intravitreal injection of ranibizumab. Read More

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http://dx.doi.org/10.1097/ICB.0000000000000656DOI Listing
November 2017
1 Read

Points of Concern in Post Acute Kidney Injury Management.

Nephron 2018 2;138(2):92-103. Epub 2017 Nov 2.

The incidence of acute kidney injury (AKI) will in the future remain high, partly due to an increase in comorbidities and other AKI favoring factors such as the rise in high-risk diagnostic and therapeutic interventions. AKI has emerged as a major public health concern with high human and financial costs. It has recently been demonstrated that patients surviving an AKI episode show increased all-cause mortality, chronic kidney disease (CKD), ESRD, cardiovascular events, and reduced quality of life. Read More

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http://dx.doi.org/10.1159/000484146DOI Listing
November 2017
9 Reads

Effects of dietary nitrate supplementation on the response to extremity cooling and endothelial function in individuals with cold sensitivity. A double blind, placebo controlled, crossover, randomised control trial.

Nitric Oxide 2017 Nov 20;70:76-85. Epub 2017 Sep 20.

Department of Sport and Exercise Science, University of Portsmouth, UK. Electronic address:

Individuals with cold sensitivity have low peripheral skin blood flow and skin temperature possibly due to reduced nitric oxide (NO•) bioavailability. Beetroot has a high concentration of inorganic nitrate and may increase NO-mediated vasodilation. Using a placebo-controlled, double blind, randomised, crossover design, this study tested the hypotheses that acute beetroot supplementation would increase the rate of cutaneous rewarming following a local cold challenge and augment endothelium-dependent vasodilation in cold sensitive individuals. Read More

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http://dx.doi.org/10.1016/j.niox.2017.09.005DOI Listing
November 2017
4 Reads

High-pressure injection injury: benign appearance belies potentially devastating consequences.

Med J Aust 2017 06;206(11):477

Royal Children's Hospital Melbourne, Melbourne, VIC.

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June 2017
3 Reads

Nonoperative Management and Novel Imaging for Posterior Circumflex Humeral Artery Injury in Volleyball.

Curr Sports Med Rep 2017 Sep/Oct;16(5):317-321

1Department of Radiology and Nuclear Medicine, Academic Medical Center/University of Amsterdam, Amsterdam, THE NETHERLANDS; 2Coronel Institute of Occupational Health, Amsterdam Public Health research institute, Academic Medical Center/University of Amsterdam, THE NETHERLANDS.

We report on a 34-yr-old male elite volleyball player with symptomatic emboli in the spiking hand from a partially thrombosed aneurysm of the posterior circumflex humeral artery (PCHA) in his dominant shoulder. At initial diagnosis and follow-up, a combination of time-resolved and high-resolution steady state contrast-enhanced magnetic resonance angiography (CE-MRA) enabled detailed visualization of: (1) emboli that were not detectable by vascular ultrasound; and (2) the PCHA aneurysm, including compression during abduction and external rotation (ABER provocation). At 15-month follow-up, including forced cessation of volleyball activities over the preceding 9 months, the PCHA aneurysm remained unchanged. Read More

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http://dx.doi.org/10.1249/JSR.0000000000000397DOI Listing
March 2018
6 Reads

[Functional outcome following high-pressure injection injuries of the hand].

Handchir Mikrochir Plast Chir 2017 Aug 14;49(3):162-168. Epub 2017 Aug 14.

 High-pressure injection injuries are devastating injuries that often lead to an amputation of the primarily affected finger. The available literature mainly focuses on amputation rates, while there is a lack of knowledge regarding functional results.  Between 1998 and 2016, 47 cases of high-pressure injection injuries of the hand were registered in our department. Read More

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http://dx.doi.org/10.1055/s-0043-115391DOI Listing
August 2017
32 Reads

Acute Alcohol Binge Deteriorates Metabolic and Respiratory Compensation Capability After Blunt Chest Trauma Followed by Hemorrhagic Shock-A New Research Model.

Alcohol Clin Exp Res 2017 Sep 9;41(9):1559-1567. Epub 2017 Aug 9.

Department of Trauma, Hand and Reconstructive Surgery, University Hospital Frankfurt, Goethe-University, Frankfurt am Main, Germany.

Background: The clinical relevance of blunt (thoracic) chest trauma (TxT) and hemorrhagic shock is indisputable due to the high prevalence of this injury type, as well as its close association with mortality and/or preventable deaths. Furthermore, there is an ongoing discussion about the influence of alcohol in trauma patients. Thus, we established a model of TxT followed by hemorrhagic shock with resuscitation (H/R) in alcohol-intoxicated rats. Read More

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http://dx.doi.org/10.1111/acer.13446DOI Listing
September 2017
27 Reads

Role of Hemorrhagic Shock in Experimental Polytrauma.

Shock 2018 02;49(2):154-163

Institute of Clinical and Experimental Trauma-Immunology, University Hospital of Ulm.

Hemorrhagic shock (HS) after tissue trauma increases the complication and mortality rate of polytrauma (PT) patients. Although several murine trauma models have been introduced, there is a lack of knowledge about the exact impact of an additional HS. We hypothesized that HS significantly contributes to organ injury, which can be reliably monitored by detection of specific organ damage markers. Read More

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http://dx.doi.org/10.1097/SHK.0000000000000925DOI Listing
February 2018
17 Reads

Does Incremental Positioning (Weight Shifts) Reduce Pressure Injuries in Critical Care Patients?

J Wound Ostomy Continence Nurs 2017 Jul/Aug;44(4):319-323

Lee Ann Krapfl, RN, CWOCN, Mercy Medical Center, Dubuque, Iowa. Julia Langin, RN, CWON, CMSRN, University of Iowa Hospitals and Clinics, Iowa City, Iowa. Caitlin A. Pike, MLS, AHIP, Indiana University-Purdue University, Indianapolis, Indiana. Patricia Pezzella, RN, CWOCN, University of Iowa Hospitals and Clinics, Iowa City, Iowa.

Background: Incremental positioning or weight shifts are often suggested as an alternative to standard repositioning/turning in critical care patients deemed clinically unstable.

Objective: This evidence-based report card reviews whether incremental positioning and/or weight shifts reduce hospital-acquired sacral/buttocks pressure injuries in critical care patients deemed too unstable to turn.

Methods And Search Strategy: A scoping review of the literature was conducted for studies related to repositioning and hospital-acquired pressure injuries in high-risk, critical care patients. Read More

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http://dx.doi.org/10.1097/WON.0000000000000340DOI Listing
November 2017
37 Reads

Remote Ischemic Perconditioning to Reduce Reperfusion Injury During Acute ST-Segment-Elevation Myocardial Infarction: A Systematic Review and Meta-Analysis.

J Am Heart Assoc 2017 May 17;6(5). Epub 2017 May 17.

Division of Emergency Medicine, Department of Family and Community Medicine, University of Toronto, Ontario, Canada

Background: Remote ischemic conditioning (RIC) is a noninvasive therapeutic strategy that uses brief cycles of blood pressure cuff inflation and deflation to protect the myocardium against ischemia-reperfusion injury. The objective of this systematic review was to determine the impact of RIC on myocardial salvage index, infarct size, and major adverse cardiovascular events when initiated before catheterization.

Methods And Results: Electronic searches of Medline, Embase, and Cochrane Central Register of Controlled Trials were conducted and reference lists were hand searched. Read More

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http://dx.doi.org/10.1161/JAHA.117.005522DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524098PMC
May 2017
19 Reads

[Morel-Lavallée lesion : Severely injured 13 year old after being run over].

Anaesthesist 2017 Sep 4;66(9):672-678. Epub 2017 May 4.

Klinik für Unfallchirurgie und Orthopädie, Berufsgenossenschaftliche Unfallklinik Ludwigshafen, Ludwigshafen, Deutschland.

Accidents in which a person is run over are often associated with multiple serious injuries. Immediate bleeding control is crucial. Pressure and shear stress at the borders of subcutaneous tissue to the muscle fascia can cause hypoperfusion and the emergence of blood-filled cavities that are associated with a high risk of infection and necrosis, a so-called Morel-Lavallée lesion. Read More

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http://dx.doi.org/10.1007/s00101-017-0318-0DOI Listing
September 2017
7 Reads

Soft Tissue Reconstruction of Complete Circumferential Defects of the Upper Extremity.

Arch Plast Surg 2017 Mar 15;44(2):117-123. Epub 2017 Mar 15.

Division of Plastic Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.

Background: Upper extremity soft tissue defects with complete circumferential involvement are not common. Coupled with the unique anatomy of the upper extremity, the underlying etiology of such circumferential soft tissue defects represent additional reconstructive challenges that require treatment to be tailored to both the patient and the wound. The aim of this study is to review the various options for soft tissue reconstruction of complete circumferential defects in the upper extremity. Read More

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http://dx.doi.org/10.5999/aps.2017.44.2.117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5366518PMC
March 2017
34 Reads

Use of Processed Nerve Allografts to Repair Nerve Injuries Greater Than 25 mm in the Hand.

Ann Plast Surg 2017 Jun;78(6S Suppl 5):S292-S295

From the *Division of Plastic Surgery, University of Kentucky, Lexington, KY; †Arizona Center for Hand Surgery, Phoenix, AZ; ‡Institute for Nerve, Hand, and Reconstructive Surgery, Rutherford, NJ; §Division of Plastic and Reconstructive Surgery, University of Washington, Harborview Medical Center, Seattle, WA; ∥Department of Plastic Surgery, Vanderbilt University, Nashville, TN; ¶Indiana Hand to Shoulder Center, Indianapolis, IN; #Duke University Department of Orthopedic Surgery, Durham, NC; and **The Buncke Clinic, San Francisco, CA.

Processed nerve allografts (PNAs) have been demonstrated to have improved clinical results compared with hollow conduits for reconstruction of digital nerve gaps less than 25 mm; however, the use of PNAs for longer gaps warrants further clinical investigation. Long nerve gaps have been traditionally hard to study because of low incidence. The advent of the RANGER registry, a large, institutional review board-approved, active database for PNA (Avance Nerve Graft; AxoGen, Inc, Alachua, FL) has allowed evaluation of lower incidence subsets. Read More

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http://dx.doi.org/10.1097/SAP.0000000000001037DOI Listing

Tumefactive foreign body giant cell reaction following high-pressure paint injection injury: A case report and review of literature.

J Cutan Pathol 2017 May 16;44(5):474-476. Epub 2017 Feb 16.

Department of Pathology and Laboratory Medicine, University of Texas Health Science Center at Houston, Houston, Texas.

High-pressure paint injection injury is an uncommon but well-described injury. The histologic features of long-term paint injection injury with retained material are less recognized. A 46-year-old male presented clinically as "recurrent giant cell tumor of tendon sheath. Read More

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http://doi.wiley.com/10.1111/cup.12905
Publisher Site
http://dx.doi.org/10.1111/cup.12905DOI Listing
May 2017
5 Reads

[Influence of the Weather on the Incidence of Fractures in the Elderly].

Acta Chir Orthop Traumatol Cech 2016 ;83(4):269-273

I. chirurgická klinika 1. lékařské fakulty Univerzity Karlovy v Praze a Všeobecné fakultní nemocnice, Praha.

PURPOSE OF THE STUDY The incidence of geriatric fractures (proximal femur, distal radius, proximal humerus and thoracolumbar spine injuries) in the population increases with ageing. However, the role of weather conditions, such as icy and slippery winter, should not be overlooked. A deeper insight into this relationship may bring about a better understanding of the fracture aetiology and thus allow for improvement in the prevention of fractures in elderly people. Read More

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February 2017
4 Reads

Quantitative Evaluation of the Mechanical Risks Caused by Focal Cartilage Defects in the Knee.

Sci Rep 2016 11 29;6:37538. Epub 2016 Nov 29.

Department of Applied Physics, University of Eastern Finland, POB 1627, FI-70211 Kuopio, Finland.

Focal cartilage lesions can proceed to severe osteoarthritis or remain unaltered even for years. A method to identify high risk defects would be of utmost importance to guide clinical decision making and to identify the patients that are at the highest risk for the onset and progression of osteoarthritis. Based on cone beam computed tomography arthrography, we present a novel computational model for evaluating changes in local mechanical responses around cartilage defects. Read More

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http://dx.doi.org/10.1038/srep37538DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5126640PMC
November 2016
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Efficacy of Monitoring Devices in Support of Prevention of Pressure Injuries: Systematic Review and Meta-analysis.

Adv Skin Wound Care 2016 Dec;29(12):567-574

Gurjot S. Walia, BS • Research Fellow • Department of Plastic and Reconstructive Surgery • Johns Hopkins University School of Medicine • Baltimore, Maryland Alison L. Wong, MD, MSE • Plastic Surgery Resident • Division of Plastic Surgery • Dalhousie University • Halifax, Nova Scotia, Canada • Graduate Student • Center for Bioengineering Innovation and Design • Johns Hopkins University Whiting School of Engineering • Baltimore, Maryland Andrea Y. Lo, BS • Summer Research Fellow • Department of Plastic and Reconstructive Surgery • Johns Hopkins University School of Medicine • Baltimore, Maryland Gina A. Mackert, MD • Plastic Surgery Resident • Department of Hand, Plastic, and Reconstructive Surgery • Burn Center, Trauma Center • Ludwigshafen, Germany • Department of Plastic Surgery • University of Heidelberg, Germany • Heidelberg, Germany Hannah M. Carl, BS • Medical Student • Department of Plastic and Reconstructive Surgery • Johns Hopkins University School of Medicine • Baltimore, Maryland Rachel A. Pedreira, BA • Medical Student • Department of Plastic and Reconstructive Surgery • Johns Hopkins University School of Medicine • Baltimore, Maryland Ricardo Bello, MD, MPH • Postdoctoral Fellow • Department of Plastic and Reconstructive Surgery • Johns Hopkins University School of Medicine • Baltimore, Maryland Carla S. Aquino, MSN, RN • Coordinator • Nursing Clinical Quality and Magnet Program • Department of Nursing Administration • Johns Hopkins Hospital • Baltimore, Maryland William V. Padula, PhD • Assistant Professor • Department of Health Policy and Management • Johns Hopkins University Bloomberg School of Public Health • Baltimore, Maryland Justin M. Sacks, MD, MBA • Assistant Professor • Department of Plastic and Reconstructive Surgery • Johns Hopkins University School of Medicine • Baltimore, Maryland.

General Purpose: To present a systematic review of the literature assessing the efficacy of monitoring devices for reducing the risk of developing pressure injuries.

Target Audience: This continuing education activity is intended for physicians, physician assistants, nurse practitioners, and nurses with an interest in skin and wound care.

Learning Objectives/outcomes: After participating in this educational activity, the participant should be better able to:1. Read More

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http://dx.doi.org/10.1097/01.ASW.0000504579.83707.f6DOI Listing
December 2016
17 Reads

The effects of upper extremity aerobic exercise in patients with spinal cord injury: a randomized controlled study.

Eur J Phys Rehabil Med 2017 Apr 8;53(2):219-227. Epub 2016 Nov 8.

Department of Biostatistics and Medical Informatics, Faculty of Medicine, Ege University, İzmir, Turkey.

Background: Immobility and secondary complications, including cardiopulmonary disease, pressure ulcers, and pain, occur in patients with spinal cord injury (SCI). These patients also have difficulty coping with the strain of daily activities. Thus, it is important for SCI patients to engage in aerobic exercise in order to be able to cope adequately with the strain of activities and SCI-related complications. Read More

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http://dx.doi.org/10.23736/S1973-9087.16.03804-1DOI Listing
April 2017
14 Reads

Microsurgical reconstruction for post-traumatic defects of lower leg in the elderly: A comparative study.

Injury 2016 Nov 6;47(11):2558-2564. Epub 2016 Sep 6.

Department of Hand-, Plastic and Reconstructive Surgery, Burn Center, BG Trauma Center Ludwigshafen, University of Heidelberg, 67071 Ludwigshafen, Germany. Electronic address:

Background: Lower leg microsurgical reconstruction in the elderly is challenging, especially for post - traumatic defects. The present study aimed to evaluate the risk factors, management and outcome of free tissue transfer in patients older than 65 years of post-traumatic defects.

Methods: Retrospective chart review was performed for all patients older than 18 years undergoing free tissue transfer for post-traumatic lower leg reconstruction from April 2000 to November 2014. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00201383163044
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http://dx.doi.org/10.1016/j.injury.2016.09.010DOI Listing
November 2016
23 Reads

Alcohol consumption and the risk for renal hyperfiltration in the general Chinese population.

Eur J Clin Nutr 2017 04 2;71(4):500-505. Epub 2016 Nov 2.

Department of Endocrinology, Fujian Provincial Hospital, Fujian Academy of Medical Sciences, Fujian Medical University, Fuzhou, China.

Background/objectives: Glomerular hyperfiltration has been considered an early marker of kidney injury in prediabetes and prehypertension. Heavy alcohol consumption remains highly prevalent and is considered a major public health problem worldwide. The degree of glomerular hyperfiltration associated with alcohol consumption remains unclear. Read More

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http://dx.doi.org/10.1038/ejcn.2016.168DOI Listing
April 2017
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Pulling Harder than the Hamate Tolerates: Evaluation of Hamate Injuries in Rock Climbing and Bouldering.

Wilderness Environ Med 2016 Dec 26;27(4):492-499. Epub 2016 Oct 26.

Department of Sports Orthopedics, Sports Medicine, Sports Traumatology, Department of Orthopedics and Traumatology, Klinikum Bamberg, Bamberg, Germany (Drs Lutter and Schöffl); Department of Trauma and Orthopedic Surgery, Friedrich Alexander University, Erlangen-Nuremberg, Germany (Dr Schöffl).

Objective: Hamate hook fractures are rare injuries, comprising 2% to 4% of all carpal fractures. Climbing athletes seem to be affected more frequently than others, as they strain the passive and active anatomical structures of their hands and fingers to maximum capacity during training or competing. This stress is transmitted to the hook of the hamate by tightened flexor tendons, which creates high contact pressure to the ulnar margin of the carpal tunnel. Read More

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http://dx.doi.org/10.1016/j.wem.2016.09.003DOI Listing
December 2016
26 Reads

Necrotising fasciitis of the extremities: implementation of new management technologies.

Injury 2016 Sep;47 Suppl 3:S66-S71

Septic and Reconstructive Surgery Unit, Orthopaedic Surgery Department, Vall d'Hebron University Hospital, Universitat Autònoma de Barcelona, Barcelona, Spain.

Introduction: Necrotising fasciitis (NF) is potentially life-threatening soft-tissue infection. Early diagnosis and aggressive surgical debridement are critical to decrease mortality and morbidity. The impacts of new management technologies such as hydro-bisturi-assisted debridement (HAD) and negative pressure wound therapy (NPWT) are not yet clear with respect to treatment of NF. Read More

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http://dx.doi.org/10.1016/S0020-1383(16)30609-XDOI Listing
September 2016
6 Reads

High performance mass spectrometry based proteomics reveals enzyme and signaling pathway regulation in neutrophils during the early stage of surgical trauma.

Proteomics Clin Appl 2017 01 9;11(1-2). Epub 2016 Nov 9.

Laboratory of Biochemistry and Protein Chemistry, Department of Cell Biology, Institute of Biology, University of Brasilia, Brasília, Brazil.

Purpose: In clinical conditions trauma is associated with high mortality and morbidity. Neutrophils play a key role in the development of multiple organ failure after trauma EXPERIMENTAL DESIGN: To have a detailed understanding of the neutrophil activation at primary stages after trauma, neutrophils are isolated from control and surgical trauma rats in this study. Extracted proteins are analyzed using nano liquid chromatography coupled with tandem mass spectrometry. Read More

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http://dx.doi.org/10.1002/prca.201600001DOI Listing
January 2017
42 Reads

Prevention of cardiac surgery-associated acute kidney injury.

Curr Opin Anaesthesiol 2017 Feb;30(1):76-83

Department of Anesthesiology, Intensive Care and Pain Medicine, University of Münster, Münster, Germany.

Purpose Of Review: Cardiac surgery-associated acute kidney injury (CSA-AKI) is a frequently occurring complication. It carries the risks of increasing mortality and development of chronic kidney disease. The complex pathophysiologic mechanisms still remain unexplained to a large extent. Read More

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http://www.biomedcentral.com/content/pdf/s13054-014-0517-x.p
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http://pdfs.journals.lww.com/co-anesthesiology/2017/02000/Pr
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http://dx.doi.org/10.1097/ACO.0000000000000392DOI Listing
February 2017
5 Reads

[V-Y ADVANCEMENT OF MEDIAL GASTROCNEMIUS MUSCLE FLAP FOR REPAIRING SOFT TISSUE DEFECTS IN MIDDLE AND LOWER SEGMENTS OF ANTERIOR TIBIA].

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2016 Sep;30(9):1122-1126

Department of Hand Surgery, Beijing Jishuitan Hospital.

Objective: To investigate the effectiveness of V-Y advanced medial gastrocnemius muscle flap to repair soft tissue defects in the middle and lower segments of the anterior tibia.

Methods: Between March 2008 and March 2014, 8 patients with skin and soft tissue defects of the anterior tibia were treated, including 6 males and 2 females with an average age of 36.2 years (range, 28-47 years). Read More

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http://dx.doi.org/10.7507/1002-1892.20160228DOI Listing
September 2016

[Clinical research of vacuum sealing drainage combined with artificial dermis for the treatment of ankle and foot soft tissue defects].

Zhongguo Gu Shang 2016 Aug;29(8):761-763

Department of Hand Surgery, the Second Affiliated Hospital of Wenzhou Medical University, Wenzhou 325027, Zhejiang, China.

Objective: To investigate the effect of vacuum sealing drainage (VSD) combined with artificial dermis for treatment of the ankle and foot soft tissue defects.

Methods: A total of 15 patients with skin and soft tissue defect of ankle and foot were treated from January 2011 to December 2013, including 10 males and 5 females, with an average age of 32.5 years old ranging from 3 to 55 years old, involving 8 cases by traffic accident, 2 cases by machine accident, 5 cases by crush injury;8 cases with soft tissue exposure, 2 cases with tendor exposure, 5 cases with bone exposure. Read More

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http://dx.doi.org/10.3969/j.issn.1003-0034.2016.08.017DOI Listing
August 2016
8 Reads

Hepatotoxicity of illegal home-made alcohols.

J Forensic Leg Med 2016 Oct 29;43:85-89. Epub 2016 Jul 29.

Mustafa Kemal University Medical Faculty, Department of Forensic Medicine, Hatay, Turkey.

Objective And Aim: Alcohol-related hepatotoxicity is not only caused by excessive alcohol consumption but also caused and even accelerated by hepatotoxic ingredients other than ethanol. Concentrations of hepatotoxic substances might be significantly high, particularly in illegally produced home-made alcohols. In this study we aim to analyze the hepatotoxic effects of a home-made alcohol traditionally called "bogma raki" in Turkey. Read More

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http://dx.doi.org/10.1016/j.jflm.2016.07.014DOI Listing
October 2016
10 Reads