Pediatr Cardiol 2021 Dec 22;42(8):1862-1870. Epub 2021 Jul 22.
Section of Cardiac Surgery, Department of Surgery, Dentistry, Pediatrics and Gynecology, University of Verona, O. C. M. Piazzale Stefani 1, 37126, Verona, Italy.
During cardiopulmonary bypass (CPB), high flows can allow an adequate perfusion to kidneys, but, on the other hand, they could cause emboli production, increased vascular pressure, and a more intense inflammatory response, which are in turn causes of renal damage. Along with demographic variables, other intra-operative management and post-operative events, this might lead to Acute kidney injury (AKI) in infants undergoing cardiac surgery. The aim of our study was to investigate if a CPB strategy with flow requirements based on monitoring of continuous metabolic and hemodynamic parameters could have an impact on outcomes, with a focus on renal damage. Read More