43,851 results match your criteria Hand Infections

Effects of the COVID-19 Pandemic on Spinal Fusion Procedures for Spinal Infections in a Nationwide Hospital Network in Germany.

J Neurol Surg A Cent Eur Neurosurg 2022 Jun 27. Epub 2022 Jun 27.

Faculty of Health Sciences Brandenburg, Brandenburg Medical School Theodor Fontane, Bad Saarow, Germany.

Background:  The full impact of the COVID-19 pandemic on surgical spine care is difficult to assess due to a lack in nationwide evidence from more recent phases of the pandemic. We aimed to describe changes in in-hospital processes associated with spinal fusion procedures in the treatment of spinal infections (SI) during different phases of the pandemic.

Methods:  In this retrospective observational study, we examined the in-hospital prevalence and outcomes of spinal fusion procedures for SI (along with patient characteristics, rates of transfer to intensive care units, and mortality rates) during the first four waves of the pandemic compared with the corresponding prepandemic periods in 2019. Read More

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Assessment of disinfectant efficacy in reducing microbial growth.

PLoS One 2022 27;17(6):e0269850. Epub 2022 Jun 27.

Reference Laboratory for Microbiology, Executive Department of Reference Laboratories, Research and Laboratories Sector, Saudi Food and Drug Authority (SFDA), Riyadh, Saudi Arabia.

The incidence of hospital- and community-acquired infections has been dramatically increased worldwide. Accordingly, hands hygiene and the use of disinfectants have been increased leading to the expansion in hand sanitizers production to meet public demand. This study was conducted to assess the efficiency of common disinfectants in the market of Riyadh, Saudi Arabia in inhibiting the microbial growth during the time of Coronavirus disease 2019 (COVID-19) pandemic. Read More

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A Qualitative Examination of Interprofessional Teamwork for Infection Prevention: Development of a Model and Solutions.

Med Care Res Rev 2022 Jun 25:10775587221103973. Epub 2022 Jun 25.

The Ohio State University, Columbus, USA.

Health care-associated infections (HAIs), such as central line-associated bloodstream infections (CLABSIs) and catheter-associated urinary tract infections (CAUTIs), are associated with patient mortality and high costs to the health care system. These are largely preventable by practices such as prompt removal of central lines and Foley catheters. While seemingly straightforward, these practices require effective teamwork between physicians and nurses to be enacted successfully. Read More

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COVID-19 Infectious Disease Prevention and Mitigation Practices by Chiropractic Physicians and Licensed Massage Therapists in Mississippi: A Needs Assessment to Inform Health Education and Promotion.

J Chiropr Med 2022 Jun 18. Epub 2022 Jun 18.

College of Nursing and Health Professors, University of Southern Mississippi, Hattiesburg, Mississippi.

Objective: The purpose of this study was to assess self-reported infection prevention processes and their effect on businesses of chiropractic doctors (DCs) and licensed massage therapists (LMTs) in Mississippi during the COVID-19 pandemic.

Methods: We developed a survey that was electronically delivered to all licensed DCs and LMTs in Mississippi between August and September 2020. Assessments were made using Qualtrics software, with data management and subsequent analysis including Pearson's χ test. Read More

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Unveiling the Pathogenic Bacteria Causing Descending Necrotizing Mediastinitis.

Front Cell Infect Microbiol 2022 8;12:873161. Epub 2022 Jun 8.

Department of Oral and Maxillofacial Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.

The combination of maxillofacial infections (MI) with descending necrotizing mediastinitis (DNM) is a complex disease characterized by rapid development and high mortality. Here, we performed metagenomic next-generation sequencing (mNGS) using samples from 21 patients with MI and eight patients with DNM. In this study, we found that the species richness of the DNM group was higher than that of the MI group, and the species diversity of the DNM group was higher than that of the MI group, with no statistically significant differences between groups (P > 0. Read More

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Public Health Issue of Indoor Dilution Ventilation for Disease Prevention Versus PM2.5 in Intake Air in Auditoriums of Premier Engineering Institutes in India.

Raja Singh

Cureus 2022 May 23;14(5):e25258. Epub 2022 May 23.

Architecture, School of Planning and Architecture, New Delhi, IND.

Background: Dilution ventilation by enhancing fresh air intake has been prescribed to reduce airborne infection spread during the COVID-19 pandemic. This is all the more important in assembly spaces like auditoriums. Premier technology institutes have large campuses with large auditoriums for academic and cultural events in India. Read More

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Is the World Health Organization Multimodal Hand Hygiene Improvement Strategy applicable and effective at the primary care level in resource-limited settings? A quantitative assessment in healthcare centers of Faranah, Guinea.

IJID Reg 2022 Jun 3;3:27-33. Epub 2022 Mar 3.

Centre for International Health Protection, Robert Koch Institute, Nordufer 20, 13353 Berlin, Germany.

Background: The World Health Organization Multimodal Hand Hygiene Improvement Strategy aims at reducing healthcare-associated infections; however, evidence of applicability and effectiveness at the primary care level is scarce, especially in healthcare centers in resource-limited settings. The objectives of this study were to improve hand hygiene knowledge and compliance at two healthcare centers in the region of Faranah, Guinea, to increase the availability of alcohol-based hand rub (ABHR), and to assess the effectiveness of the strategy at the primary care level.

Methods: Knowledge, perceptions, and compliance were assessed prior to the intervention and compared to those of two follow-up assessments, immediately and 6 months after the intervention. Read More

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The presumed receptivity and susceptibility to monkeypox of European animal species.

Nadia Haddad

Infect Dis Now 2022 Jun 23. Epub 2022 Jun 23.

Anses, INRAe, Ecole Nationale Vétérinaire d'Alfort, UMR BIPAR, Laboratoire de Santé Animale, Maisons-Alfort, F-94700 France. Electronic address:

The Monkeypox virus belongs to the Orthopoxviral genus, as does the specifically human smallpox virus. It is zoonotic and had never previously been considered as capable of human-to-human transmission over more than nine viral generation cycles. While relevant animal reservoirs have yet to be identified, non-human primates (NHP) are only accidental hosts. Read More

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Complications and range of motion of patients with an elbow dislocation treated with a hinged external fixator: a retrospective cohort study.

Eur J Trauma Emerg Surg 2022 Jun 25. Epub 2022 Jun 25.

Trauma Research Unit, Department of Surgery, Erasmus MC, University Medical Center Rotterdam, P.O. Box 2040, 3000 CA, Rotterdam, The Netherlands.

Purpose: Elbow dislocations are at risk for persistent instability and stiffness of the joint. Treatment with a hinged external fixation provides elbow joint stability, and allows early mobilization to prevent stiffness. Mounting a hinged elbow fixator correctly, however, is technically challenging. Read More

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Awareness of Pet Owners in Riyadh Regarding Pet-Related Health Risks and Their Associated Preventative Measures.

Vector Borne Zoonotic Dis 2022 Jun 24. Epub 2022 Jun 24.

College of Medicine, King Saud University, Riyadh, Saudi Arabia.

This study aims to determine the sociodemographic characteristics of pet owners and their sources of information regarding pet-related health risks. It also assesses pet owners' perception of pet-related health risks and evaluates their attitudes and practices regarding preventative measures toward pet-related health risks. A cross-sectional study was conducted in Riyadh, Saudi Arabia from September 2020 to February 2021. Read More

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Luliconazole topical dermal drug delivery for superficial fungal infections: Penetration hurdles and role of functional nanomaterials.

Curr Pharm Des 2022 Jun 23. Epub 2022 Jun 23.

Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research, Hyderabad, Telangana, India.

Luliconazole is the first and only anti-fungal agent approved for the short-term treatment of superficial fungal infections. However, commercially available conventional topical dermal drug delivery cargo of luliconazole is associated with certain limitations like lower skin permeation and shorter skin retention of drug. Therefore, present review is an attempt to decode the penetration hurdles in luliconazole topical dermal drug delivery. Read More

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Analysis of Blood Transfusion Request and Utilization Pattern at the Blood Centre of the Tribal District, Dahod, India.

Cureus 2022 May 23;14(5):e25237. Epub 2022 May 23.

Pathology, Zydus Medical College and Hospital, Dahod, IND.

Introduction Blood is the most commonly donated, vital and essential tissue, saving many lives. It is better to use components instead of whole blood for maximum benefits of blood. Blood is considered a life-saving medicine, so it must be used with precautions as blood and its components can cause side effects such as transfusion-transmitted infections and various transfusion reactions in the recipients. Read More

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Hand Hygiene Auditing: Is It a Roadway to Improve Adherence to Hand Hygiene Among Hospital Personnel?

Cureus 2022 May 22;14(5):e25221. Epub 2022 May 22.

Department of Biochemistry, All India Institute of Medical Sciences, Bibinagar, Hyderabad, IND.

Background Over the years, there has been an increase in hospital-acquired infections (HAIs) among patients in India. One of the main reasons is a lack of compliance with infection control guidelines, such as hand hygiene. So the present study was conducted to determine the compliance of hand hygiene among healthcare workers in a private tertiary care teaching hospital in South India. Read More

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Influenza Virus Infections in Polarized Cells.

Viruses 2022 Jun 15;14(6). Epub 2022 Jun 15.

MU Center for Influenza and Emerging Infectious Diseases, University of Missouri, Columbia, MO 65211, USA.

In humans and other mammals, the respiratory tract is represented by a complex network of polarized epithelial cells, forming an apical surface facing the external environment and a basal surface attached to the basement layer. These cells are characterized by differential expression of proteins and glycans, which serve as receptors during influenza virus infection. Attachment between these host receptors and the viral surface glycoprotein hemagglutinin (HA) initiates the influenza virus life cycle. Read More

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Molnupiravir and Its Active Form, EIDD-1931, Show Potent Antiviral Activity against Enterovirus Infections In Vitro and In Vivo.

Viruses 2022 May 25;14(6). Epub 2022 May 25.

National Engineering Research Center for the Emergency Drug, Beijing Institute of Pharmacology and Toxicology, Beijing 100850, China.

Enterovirus infections can cause hand, foot, and mouth disease (HFDM), aseptic meningitis, encephalitis, myocarditis, and acute flaccid myelitis, leading to death of infants and young children. However, no specific antiviral drug is currently available for the treatment of this type of infection. The Unites States and United Kingdom health authorities recently approved a new antiviral drug, molnupiravir, for the treatment of COVID-19. Read More

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Biological Properties of SARS-CoV-2 Variants: Epidemiological Impact and Clinical Consequences.

Vaccines (Basel) 2022 Jun 9;10(6). Epub 2022 Jun 9.

Biomedical Research Center and College of Health Sciences-QU Health, Qatar University, Doha 2713, Qatar.

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a virus that belongs to the coronavirus family and is the cause of coronavirus disease 2019 (COVID-19). As of May 2022, it had caused more than 500 million infections and more than 6 million deaths worldwide. Several vaccines have been produced and tested over the last two years. Read More

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Integrating In Vitro and In Silico Analysis of a Cationic Antimicrobial Peptide Interaction with Model Membranes of Colistin-Resistant Strains.

Pharmaceutics 2022 Jun 12;14(6). Epub 2022 Jun 12.

Research Group of Chemistry and Biotechnology, Faculty of Basic Sciences, Universidad Santiago of Cali, Cali 760035, Colombia.

Bacterial antibiotic resistance is a serious global public health concern. Infections caused by colistin-resistant (CRPa) strains represent a serious threat due to their considerable morbidity and mortality rates, since most of the current empirical antibiotic therapies are ineffective against these strains. Accordingly, cationic antimicrobial peptides (CAMPs) have emerged as promising alternatives to control resistant bacteria. Read More

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The Effects of an Intensive Rehabilitation Program on the Nutritional and Functional Status of Post-COVID-19 Pneumonia Patients.

Nutrients 2022 Jun 16;14(12). Epub 2022 Jun 16.

Grupo de Patologia Médica, Nutrição e Exercício Clínico (PaMNEC) do Centro de Investigação Interdisciplinar Egas Moniz (CiiEM), 2829-511 Almada, Portugal.

Most hospitalized COVID-19 pneumonia patients are older adults and/or have nutrition-related issues. Many are bedridden in intensive care units (ICU), a well-documented cause of malnutrition, muscle wasting, and functional impairment. Objectives: To assess the effectiveness of an intensive rehabilitation program over the nutritional/functional status of patients recovering from COVID-19 pneumonia. Read More

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Comparative Evaluation of Antimicrobial, Antiamoebic, and Antiviral Efficacy of Ophthalmic Formulations.

Microorganisms 2022 Jun 4;10(6). Epub 2022 Jun 4.

Department of Pharmacy, University of Salerno, 84084 Fisciano, Italy.

The extensive use of ophthalmic antibiotics is contributing to the appearance of resistant bacterial strains, which require prolonged and massive treatments with consequent detrimental outcomes and adverse effects. In addition to these issues, antibiotics are not effective against parasites and viruses. In this context, antiseptics could be valuable alternatives. Read More

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Contribution of Topical Agents such as Hyaluronic Acid and Silver Sulfadiazine to Wound Healing and Management of Bacterial Biofilm.

Medicina (Kaunas) 2022 Jun 20;58(6). Epub 2022 Jun 20.

Department of Plastic and Reconstructive Surgery, Faculty of Medicine, Fukuoka University, Fukuoka 814-0180, Japan.

Wound healing is commonly associated with critical bacterial colonization or bacterial infection, which induces prolonged inflammation, resulting in delayed re-epithelialization. An appropriate wound dressing requires a humid environment, which also functions as a barrier against bacterial contamination and will accelerate a regenerative response of the wound. Silver sulfadiazine (SSD) is used to prevent wound infection. Read More

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CFD Numerical Simulation in Building Drainage Stacks as an Infection Pathway of COVID-19.

Int J Environ Res Public Health 2022 Jun 18;19(12). Epub 2022 Jun 18.

Department of Architecture, National Taiwan University of Science and Technology, Taipei 10607, Taiwan.

Being aware of global pandemics, this research focused on the potential infection routes in building drainage systems. Case studies have found that dysfunctional building drainage systems not only failed to block contaminants but also potentially became a route for the spreading of viruses. Several fluid simulations in pipelines were conducted in this research using COMSOL Multiphysics. Read More

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Factors Predicting Post-Traumatic Positive and Negative Psychological Changes Experienced by Nurses during a Pandemic COVID-19: A Cross-Sectional Study.

Int J Environ Res Public Health 2022 Jun 9;19(12). Epub 2022 Jun 9.

Department of Anaesthesiological and Intensive Care Nursing, Medical University of Lublin, Chodźki 7 Str., PL-20-093 Lublin, Poland.

It is common knowledge that COVID-19 affects physiopathological changes in all systems of the human body. On the other hand, events related to the COVID-19 pandemic also have a significant impact on the social and mental sphere of human functioning. The aim of this study is to determine the relationship between selected sociodemographic variables and selected subjective cognitive resources, and the positive and negative perception of the consequences of the COVID-19 pandemic in a group of nurses working in Poland. Read More

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The DendrisCHIP Technology as a New, Rapid and Reliable Molecular Method for the Diagnosis of Osteoarticular Infections.

Diagnostics (Basel) 2022 May 30;12(6). Epub 2022 May 30.

Dendris SAS, 335 rue du Chêne Vert, F-31670 Labège, France.

Osteoarticular infections are major disabling diseases that can occur after orthopedic implant surgery in patients. The management of these infections is very complex and painful, requiring surgical intervention in combination with long-term antibiotic treatment. Therefore, early and accurate diagnosis of the causal pathogens is essential before formulating chemotherapeutic regimens. Read More

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Aberrant Synaptic Pruning in CNS Diseases: A Critical Player in HIV-Associated Neurological Dysfunction?

Cells 2022 06 16;11(12). Epub 2022 Jun 16.

Stony Brook University Pain and Analgesia Research Center (SPARC), Department of Anesthesiology, Renaissance School of Medicine, Stony Brook University, Stony Brook, NY 11794, USA.

Even in the era of effective antiretroviral therapies, people living with Human Immunodeficiency Virus (HIV) are burdened with debilitating neurological dysfunction, such as HIV-associated neurocognitive disorders (HAND) and HIV-associated pain, for which there are no FDA approved treatments. Disruption to the neural circuits of cognition and pain in the form of synaptic degeneration is implicated in developing these dysfunctions. Glia-mediated synaptic pruning is a mechanism of structural plasticity in the healthy central nervous system (CNS), but recently, it has been discovered that dysregulated glia-mediated synaptic pruning is the cause of synaptic degeneration, leading to maladaptive plasticity and cognitive deficits in multiple diseases of the CNS. Read More

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Bacterial Resistance to Antibiotics and Clonal Spread in COVID-19-Positive Patients on a Tertiary Hospital Intensive Care Unit, Czech Republic.

Antibiotics (Basel) 2022 Jun 8;11(6). Epub 2022 Jun 8.

Department of Microbiology, Faculty of Medicine and Dentistry, Palacky University Olomouc, Hnevotinska 3, 779 00 Olomouc, Czech Republic.

This observational retrospective study aimed to analyze whether/how the spectrum of bacterial pathogens and their resistance to antibiotics changed during the worst part of the COVID-19 pandemic (1 November 2020 to 30 April 2021) among intensive care patients in University Hospital Olomouc, Czech Republic, as compared with the pre-pandemic period (1 November 2018 to 30 April 2019). A total of 789 clinically important bacterial isolates from 189 patients were cultured during the pre-COVID-19 period. The most frequent etiologic agents causing nosocomial infections were strains of (17%), (11%), (10%), coagulase-negative staphylococci (9%), (8%), (6%), (5%), (5%) and (5%). Read More

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Biodiversity in Times of COVID-19 and its Relationship with the Socio-Economic and Health Context: A Look from the Digital Media.

Environ Manage 2022 Jun 23. Epub 2022 Jun 23.

Departamento de Biología, Facultad de Ciencias, Universidad de La Serena, La Serena, Chile.

The COVID-19 pandemic has caused a pause in people's activities and a socio-economic crisis worldwide due to confinement. This situation is an unprecedented opportunity to understand how these changes may impact biodiversity and its conservation, as well as to study human-nature interaction. Biodiversity plays an essential role in conservation and economic activities, and in countries with greater inequality and low gross domestic product (GDP), biodiversity could have a low priority. Read More

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Chicken embryo lethality assay for determining the lethal dose, tissue distribution and pathogenicity of clinical Enterococcus cecorum isolates from poultry.

Sci Rep 2022 Jun 23;12(1):10675. Epub 2022 Jun 23.

Department of Pathology and Veterinary Diagnostics, Institute of Veterinary Medicine, Warsaw University of Life Sciences - SGGW, Nowoursynowska 159c St., 02-776, Warsaw, Poland.

Enterococcus cecorum is a well-known component of the normal poultry intestinal microbiota and an important bacterial pathogen. Infections caused by E. cecorum have negative effects on the poultry production worldwide. Read More

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Is latent Toxoplasma gondii infection associated with the occurrence of schizophrenia? A case-control study.

PLoS One 2022 23;17(6):e0270377. Epub 2022 Jun 23.

Department of Microbiology, Immunology and Parasitology, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.

Introduction: Neurotropic pathogens such as Toxoplasma gondii (T. gondii) which result in chronic infections in the brain are associated with mental illnesses. In view of this, a growing body of literature has revealed the possible interaction of schizophrenia and T. Read More

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Assessing the impact of ambient temperature on the risk of hand, foot, and mouth disease in Guangdong, China: New insight from the disease severity and burden.

PLoS Negl Trop Dis 2022 Jun 23;16(6):e0010470. Epub 2022 Jun 23.

Department of Medical Statistics, School of Public Health, Sun Yat-sen University, Guangzhou, China.

Background: The association between the incidence of hand, foot, and mouth disease (HFMD) and ambient temperature has been well documented. Although the severity of symptoms is an important indicator of disease burden and varies significantly across cases, it usually was ignored in previous studies, potentially leading to biased estimates of the health impact of temperature.

Methods: We estimated the disability-adjusted life year (DALY) by considering the severity of symptoms for each HFMD case reported during 2010-2012 in Guangdong and used distributed lag-nonlinear models to estimate the association between the daily average temperature and daily DALY of HFMD cases at the city-level. Read More

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Attitudes and perceptions of Nigerians regarding receiving COVID-19 vaccines: an online cross-sectional study.

Pan Afr Med J 2022 25;41:247. Epub 2022 Mar 25.

College of Health Science, Mizan- Tepi University, Tepi bushira, Ethiopia.

Introduction: the success of controlling pandemics like COVID-19 can be achieved through its vaccination program. Besides masks, social distance, and good hand hygiene, a rapid vaccine program is crucial in controlling this COVID-19 pandemic. Thus, this study aimed to assess the attitudes and perceptions of Nigerians regarding accepting the COVID-19 vaccine. Read More

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