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Cost Eff Resour Alloc 2022 Jun 25;20(1):27. Epub 2022 Jun 25.

Department of Ophthalmology, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.

Background And Aims: The misconception of the purpose of strabismus treatment has, on the one hand, affected the motivation of strabismus patients to seek care and, on the other hand, has resulted in strabismus not being covered by health insurance, both of which interact to limit the motivation of strabismus patients and also impose a financial burden on strabismus patients. Previous studies on the cost of strabismus had only addressed the cost utility and functional and psychosocial benefits of strabismus surgery. The aim of this study was to estimate the direct medical expenditure incurred for strabismus surgery and analyze the trend for the period 2014-2019 using the data collected by local eye hospitals in northeast China. Read More

J Clin Med 2022 Jun 13;11(12). Epub 2022 Jun 13.

Hand and Arm Center, Department of Orthopedic Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.

In the original publication [... Read More

Harefuah 2022 Jun;161(6):349-354

The Multidisciplinary Center for Functional Neurosurgery, Assuta Medical Centers , Tel Aviv, Israel.

Introduction: About one percent (over 81,000 patients) of the Israeli population suffer from epilepsy. The main treatment for this condition is medication, but about a third of the patients suffer from drug-resistant epilepsy (DRE). Each year about 5,000 new patients are diagnosed with epilepsy, of whom 3,000 are children. Read More

Acta Clin Croat 2021 Dec;60(4):749-757

1Department of Anesthesiology, Resuscitation, Intensive Medicine and Pain Management, Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia; 2Department of Health Studies, University of Zadar, Zadar, Croatia; 3Department of Anesthesiology, Resuscitation and Intensive Care Medicine, Zadar General Hospital, Zadar, Croatia; 4Department of Anesthesiology, Resuscitation and Intensive Care Medicine, Požega General County Hospital, Požega, Croatia; 5School of Medicine, University of Rijeka, Rijeka, Croatia; 6Department of Neurology, Rijeka University Hospital Center, Rijeka, Croatia; 7Department of Anesthesiology and Perioperative Medicine, School of Medicine, University of Missouri, Columbia, USA.

One of the most common surgeries in elderly patients is eye surgery. An increasing number of patients undergoing ambulatory eye surgery are on antithrombotic therapy. These drugs may increase the risk of perioperative bleeding associated with ophthalmic needle blocks and/or eye surgery. Read More

Pediatr Int 2022 Jan;64(1):e15225

Centre de Référence Neuromusculaire, Department of Neurology, Cliniques Universitaires de Bruxelles, Hôpital Erasme, Université libre de Bruxelles (ULB), Brussels, Belgium.

Background: Home mechanical ventilation (HMV) prolongs survival in patients with Duchenne muscular dystrophy (DMD) until ±35 years of age. This study evaluates the implementation of a HMV pilot project in children with DMD in Ukraine.

Methods: Children with DMD were invited to Kirovograd Regional Children's Clinical Hospital, Kropyvnytskyi, Ukraine, for 5 days' training with non-invasive ventilation. Read More

Acta Orthop 2022 Jun 21;93:583-587. Epub 2022 Jun 21.

Kuopio Musculoskeletal Research Unit (KMRU), University of Eastern Finland, Kuopio; Department of Orthopaedics, Traumatology and Hand Surgery, Kuopio University Hospital, Kuopio, Finland.

Background And Purpose: Manipulation under anesthesia (MUA) is considered to be effective in treating stiffness after total knee arthroplasty (TKA). However, not all patients achieve a satisfactory range of motion (ROM) after MUA. This retrospective study determined the outcome of MUA and identified the factors affecting it. Read More

J Hosp Infect 2022 Jun 17. Epub 2022 Jun 17.

Department of Infection Control, Oulu University Hospital, Finland.

Background: The improvement of hand hygiene compliance (HHC) is critical to preventing healthcare-associated infections (HCAIs). The present study explored how direct observation and feedback influences HHC among nurses and doctors in surgical and medical wards, and whether these actions impact HCAI incidence.

Methods: In this longitudinal observational study, HHC and the incidence of HCAIs were observed in six medical and seven surgical wards in a tertiary hospital in Finland from May 2013 to Dec 2020. Read More

Ann Geriatr Med Res 2022 Jun 20. Epub 2022 Jun 20.

Department of Anaesthesiology and Pain medicine, Konyang University Hospital, Myunggok Medical Research Center, Konyang University College of Medicine, Daejeon, Republic of Korea.

Background: Older patients are more vulnerable to inadvertent perioperative hypothermia. Prewarming contributes to the prevention of inadvertent perioperative hypothermia in patients under general or neuraxial anesthesia. However, the effects of brachial plexus block (BPB) on thermoregulation and the efficacy of prewarming in the prevention of hypothermia in older patients undergoing surgery with BPB remain unclear. Read More

J Public Health Afr 2022 May 24;13(1):1856. Epub 2022 May 24.

College of Medicine, Enugu State University of Science and Technology, Enugu, Enugu State, Nigeria.

Previous pandemics have had significant impact on psychological well-being of front-line health care workers. Issues such as fear of contracting the disease, high workload as a result of high numbers of infected cases, increased job stress and unavailability of personal protective equipment have been implicated in development of psychological distress in this subset of individuals. The aim of the present paper is to describe psychobehavioral responses of health care workers and potential predictors of emotional response at onset of COVID- 19 outbreak in Nigeria. Read More

Am J Otolaryngol 2022 Jun 11;43(5):103532. Epub 2022 Jun 11.

ENT, Maulana Azad Medical College, India.

Introduction: Juvenile nasopharyngeal angiofibroma(JNA) are highly vascular benign tumours originating in the sphenopalatine fossa and may extend to the pterygopalatine fossa, paranasal sinuses, and nasal cavity. The management of JNA has evolved greatly with development of endoscopy. Treatment modality has changed from open approach to endoscopic approach due to various advantages offered by the endoscopic approach. Read More

J Midlife Health 2022 Jan-Mar;13(1):67-73. Epub 2022 May 2.

Department of Obst and Gynae, S.N. Medical College, Agra, Uttar Pradesh, India.

Objectives: This study aimed to compare the diagnostic accuracy, inadequate sampling, pain during the procedure (Visual Analog Scale [VAS] score), and ease of insertion of the Karman's cannula and Pipelle biopsy for patients with abnormal uterine bleeding (AUB).

Methods: This prospective observational randomized comparative study included women of age more than 40 years with complaints of AUB. Two hundred and fifty women were randomly divided into two groups: (1) Group A ( = 125) who underwent endometrial aspiration using Karman's cannula and (2) Group B ( = 125) who underwent Pipelle endometrial sampling. Read More

Front Neurol 2022 30;13:834003. Epub 2022 May 30.

Department of Neurosurgery, University Hospital RWTH Aachen, Aachen, Germany.

The translation of preclinical stroke research into successful human clinical trials remains a challenging task. The first Stroke Therapy Academic Industry Roundtable (STAIR) recommendations for preclinical research and several other guidelines were published to address these challenges. Most guidelines recommend the use of physiological monitoring to detect the occurrence of undesired pathologies such as subarachnoid hemorrhage and to limit the variability of the infarct volume and-therefore-homogenize the experimental result for complete reporting particularly with respect to transparency and methodological rigor. Read More

Int J Prev Med 2022 27;13:73. Epub 2022 Apr 27.

Department of Plastic Surgery, Royal Devon & Exeter Hospital, Exeter, UK.

We describe a visual algorithm to help prevent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) contagion as well as manage COVID-19 disease according to categories of clinical severity. The algorithm is timely, with multiple countries worldwide declaring repeat surges in SARS-CoV-2 infections following the easing of lockdown measures. Its flowchart assimilates key effective interventions in a visual manner that will assist healthcare workers to manage COVID-19 disease algorithmically, and policymakers to suppress further SARS-CoV-2 waves. Read More

Transl Cancer Res 2022 May;11(5):1445-1450

Department of Anesthesiology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.

Background: Silent lung is a rare and potentially fatal disease. It is a critical sign of strong bronchospasm or extensive mucus plug blockage, which can result in the obvious weakening of breathing sounds or even disappearance of breathing sounds. Silent lung has an acute onset and rapid progress, which seriously threatens the life of patients. Read More

J Anaesthesiol Clin Pharmacol 2022 Jan-Mar;38(1):3-10. Epub 2022 Feb 4.

Consultant in Pain Medicine and Clinical Network Director Pain, St. Bartholomews Hospital, Barts Health NHS Trust West field, London.

Opioids play a crucial role in pain management in spite of causing increased hospital morbidity and related costs. It may also cause significant risks such as postoperative nausea and vomiting (PONV), sedation, sleep disturbances, urinary retention and respiratory depression (commonly referred to as opioid related adverse effects) in postoperative patients. In order to evade these opioid related side effects and also improve pain management, multimodal analgesia i. Read More

Arch Gynecol Obstet 2022 Jun 15. Epub 2022 Jun 15.

Department of Clinical Sciences, Polytechnic University of Marche Salesi Hospital, via Corridoni 11, 60123, Ancona, Italy.

Purpose: To analyze the mechanisms involved in the fetal heart rate (FHR) abnormalities after the epidural analgesia in labor.

Methods: A prospective unblinded single-center observational study on 55 term singleton pregnant women with spontaneous labor. All women recruited underwent serial bedside measurements of the main hemodynamic parameters using a non-invasive ultrasound system (USCOM-1A). Read More

Plast Reconstr Surg Glob Open 2022 May 13;10(5):e4285. Epub 2022 May 13.

Department of Surgery, Division of Plastic and Reconstructive Surgery, Michigan State University, East Lansing, Mich.

We transitioned our hand practice from the operating room (OR) to our office-based procedure room (OPR) to offer wide-awake, local anesthesia, no tourniquet (WALANT). We have established that using wide-awake virtual reality improves patient comfort and anxiety during wide-awake procedures and helps facilitate our patients' choice of venue. We aimed to assess the effect of this transition on infection rates for procedures performed by a single surgeon in the OR versus the OPR. Read More

Lasers Med Sci 2022 Jun 14. Epub 2022 Jun 14.

Adelaide Dental School, University of Adelaide, Adelaide, SA, Australia.

Purpose: Photobiomodulation (PBM) is reported in many studies to produce dental analgesia without producing thermal damage to tissues. This systematic review aims to assess in vivo studies to support the statement that PBM can produce dental analgesia.

Method: A systematic search strategy was constructed, and PubMed, Scopus, and Embase databases were searched. Read More

Tech Hand Up Extrem Surg 2022 May 4. Epub 2022 May 4.

Department of Hand Surgery, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.

We retrospectively reviewed our 34 first wrist dry arthroscopy cases using a single-use, 1.9 mm chip-on-tip system in wide-awake local anesthesia no tourniquet (WALANT). Thirteen patients were acute injuries; all acute patients underwent a magnetic resonance imaging (MRI) before arthroscopy. Read More

JBJS Essent Surg Tech 2022 Jan-Mar;12(1). Epub 2022 Feb 28.

Parc de Salut Mar, Universitat Autonoma Barcelona, Barcelona, Spain.

Proximal medial gastrocnemius release (PMGR) is a technique that is performed to relieve tension in the Achilles-calcaneus-plantar system when a biomechanical overload is present. One of the main indications for this technique is recalcitrant plantar fasciitis. This procedure may also be useful in second-rocker metatarsalgia or midportion Achilles tendinitis. Read More

Int J Mol Sci 2022 May 30;23(11). Epub 2022 May 30.

Department of Pharmacology and Physiology, School of Medicine and Dentistry, University Rochester, 601 Elmwood Avenue, Rochester, NY 14642, USA.

The history of direct cell-cell communication has evolved in several small steps. First discovered in the 1930s in invertebrate nervous systems, it was thought at first to be an exception to the "cell theory", restricted to invertebrates. Surprisingly, however, in the 1950s, electrical cell-cell communication was also reported in vertebrates. Read More

BMC Anesthesiol 2022 Jun 7;22(1):176. Epub 2022 Jun 7.

Department of Anesthesiology, the First Affiliated Hospital of Wenzhou Medical University, South Baixiang, Wenzhou City, 325000, Zhejiang Province, China.

Background: To study the respective peripheral and systemic mechanisms of action of dexmedetomidine, as adjuvant to regional anesthesia, we compared dexmedetomidine added to ropivacaine for mid-forearm nerve blocks, to either systemic-only dexmedetomidine, and to a control with no dexmedetomidine.

Methods: Sixty patients undergoing hand surgery were randomly divided into three groups (n = 20 per group). Each group underwent a triple-nerve (median, radial and ulnar) mid-forearm blocks with 0. Read More

J Hand Surg Am 2022 Jun 3. Epub 2022 Jun 3.

From the Philadelphia Hand to Shoulder Center, Thomas Jefferson University, King of Prussia, PA.

As demands for faster return to function, improvement in surgical scarring, and minimal disruption to personal schedule have increased, so also have the demands increased for minimally invasive procedures under the wide awake, local anesthetic, no tourniquet method. However, owing to the subcutaneous yet constrained position of the ulnar nerve at the elbow, wide-awake endoscopic cubital tunnel release has remained a technical challenge. We describe a 2-stage local anesthetic injection method that safely introduces local anesthetic within the cubital tunnel and simultaneously achieves comfort, sufficient visualization, and the ability to decompress multiple compression sites through a minimal incision. Read More

J Neuroeng Rehabil 2022 Jun 3;19(1):53. Epub 2022 Jun 3.

Department of Biomedical Engineering, University of Miami, 1251 Memorial Dr, MEA 204, Coral Gables, Miami, FL, 33146, USA.

Objective: The objective of this study was to develop a portable and modular brain-computer interface (BCI) software platform independent of input and output devices. We implemented this platform in a case study of a subject with cervical spinal cord injury (C5 ASIA A).

Background: BCIs can restore independence for individuals with paralysis by using brain signals to control prosthetics or trigger functional electrical stimulation. Read More

Hand (N Y) 2022 Jun 5:15589447221092061. Epub 2022 Jun 5.

Division of Plastic Surgery, Montreal General Hospital, McGill University, Quebec, Canada.

Background: Local anesthesia has shown to be safe and cost-effective for elective hand surgery procedures performed outside of the operating room. The economic benefits of local anesthesia compared to regional anesthesia for hand surgeries performed in the operating room involving repair of tendons, nerves, arteries, or bones are unclear. This study aimed to compare costs pertinent to hand surgeries performed in the main operating room under local anesthesia (LA) or brachial plexus (BP) block. Read More

Ulus Travma Acil Cerrahi Derg 2022 Jun;28(6):832-838

Parexel International Ltd. Chandigarh-India.

Background: Hip fractures (HF) are among the most common fractures present in the emergency department and are very painful. Pericapsular nerve group block (PENG) is a new regional anesthesia technique developed for analgesia in total hip arthroplas-ties. We aimed to determine the effectiveness of PENG block used to reduce pain in patients with HF in the emergency department. Read More

NPJ Digit Med 2022 May 31;5(1):66. Epub 2022 May 31.

Bakar Computational Health Sciences Institute, University of California San Francisco, San Francisco, CA, USA.

Machine learning (ML) and artificial intelligence (AI) algorithms have the potential to derive insights from clinical data and improve patient outcomes. However, these highly complex systems are sensitive to changes in the environment and liable to performance decay. Even after their successful integration into clinical practice, ML/AI algorithms should be continuously monitored and updated to ensure their long-term safety and effectiveness. Read More

Injury 2022 Jul 27;53(7):2573-2578. Epub 2022 May 27.

Department of Orthopaedic Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.

Introduction: One of the complications of the surgical therapy for proximal humerus fractures is fracture-related infection (FRI). This multicenter study aimed to investigate the incidence of FRI and clarify the risk factors associated with FRI in patients receiving open reduction and internal fixation for proximal humerus fracture.

Material And Methods: Among 684 patients diagnosed as having proximal humerus fracture and who were treated by surgical therapy in 13 institutions (named TRON group) from 2015 through 2020, 496 patients (men, n = 134, women, n = 362; mean [SD] age, 68. Read More

J Mater Sci Mater Med 2022 May 31;33(6):51. Epub 2022 May 31.

Polymer Chemistry & Biomaterials Research Group, Centre of Macromolecular Chemistry (CMaC), Ghent University, Krijgslaan 281 S4-bis, 9000, Ghent, Belgium.

Hand tendon injuries represent a major clinical problem and might dramatically diminish a patient's life quality. In this study, a targeted solution for flexor tendon repair was developed by combining a mechanical and biological approach. To this end, a novel acrylate-endcapped urethane-based polymer (AUP) was synthesized and its physico-chemical properties were characterized. Read More

Dis Markers 2022 17;2022:8563202. Epub 2022 May 17.

The First Affiliated Hospital, Department of Pain, Hengyang Medical School, University of South China, 421001, China.

Objective: To research the impact and mechanism of endothelin receptor A inhibitor BQ-123 combined with electroacupuncture on tibia cancer pain in rats.

Methods: Sprague-Dawley (SD) rats were randomly divided into sham group (SHAM group) and bone cancer pain model group (BCP group). The behavior of SD rats was measured. Read More