Search Our Scientific Publications & Authors

Microorganisms 2020 May 30;8(6). Epub 2020 May 30.

Department of Anesthesia and Intensive Care, University of Foggia, Azienda Ospedaliero-Universitaria Ospedali Riuniti, Viale Pinto 241, 71122 Foggia, Italy.

Ventilator-associated pneumonia (VAP) is the most common hospital-acquired infection in the intensive care unit (ICU), accounting for relevant morbidity and mortality among critically ill patients, especially when caused by multidrug resistant (MDR) organisms. The rising problem of MDR etiologies, which has led to a reduction in treatment options, have increased clinician's attention to the employment of effective prevention strategies. In this narrative review we summarized the evidence resulting from 27 original articles that were identified through a systematic database search of the last 15 years, focusing on several pathogenesis-targeted strategies which could help preventing MDR-VAP. Read More

ACS Omega 2020 May 12;5(20):11677-11686. Epub 2020 May 12.

Laboratory of Anesthesia and Critical Care Medicine, Translational Neuroscience Center and National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu 610041, China.

Formation of amyloid fibrils by misfolding α-synuclein is a characteristic feature of Parkinson's disease, but the exact molecular mechanism of this process has long been an unresolved mystery. Identification of critical amyloid peptide fragments from α-synuclein may hold the key to decipher this mystery. Focusing on consecutive hydrophobic amino acids (CHAA) in the protein sequence, in this study we proposed a sequence-based strategy for direct identification of amyloid peptide fragments in α-synuclein. Read More

Urol Case Rep 2020 Sep 21;32:101257. Epub 2020 May 21.

Department of Obstetrics and Gynecology, University Medical Center Mannheim, Heidelberg University, Mannheim, Germany.

In a 40-year-old caucasian patient with stress incontinence was a TVT operation performed with an autologous semitendinosus tendon transplant. The operation was done with spinal anesthesia. The tendon of the right musculus semitendinosus was stripped from the popliteal fossa and used instead of a synthetic tape as midurethral sling, as it is done in a classical retropubic TVT procedure. Read More

J Ultrasound 2020 May 30. Epub 2020 May 30.

Department of Orthopaedic Hand and Microsurgery Center, Osaka Ekisaikai Hospital, 2-1-10 Honden, Nishi-ku, Osaka, 550-0022, Japan.

Purpose: To evaluate the effectiveness of sonographic evaluation of the radial nerve at the first operation for closed humeral fracture cases.

Methods: Seventeen cases of closed humeral fractures were included in this study. These cases were categorized into two groups: Group P, consisting of seven cases with complete radial nerve palsy after the injuries; and Group C, consisting of ten cases without radial nerve palsy after the injuries. Read More

Rev Bras Anestesiol 2020 May 13. Epub 2020 May 13.

Meikai University School of Dentistry, Department of Diagnostic and Therapeutic Sciences, First Division of Oral and Maxillofacial Surgery, Sakado-Shi, Japan.

Background And Objectives: Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a genetic cardiomyopathy characterized by potentially lethal ventricular tachycardia. Here we describe a patient with ARVC and an Implantable Cardioverter Defibrillator (ICD) in whom maxillary sinus surgery was performed under general anesthesia.

Case Report: The patient was a 59 year-old man who was scheduled to undergo maxillary sinus surgery under general anesthesia. Read More

PLoS One 2020 29;15(5):e0233778. Epub 2020 May 29.

HepatoGastro Lab, Servicio de Ap. Digestivo del HGU Gregorio Marañón, Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM), Madrid, Spain.

The selection of the anesthetic regime is a crucial component in many experimental animal studies. In rodent models of liver disease, the combination of ketamine and diazepam (KD), generally by the intramuscular (i.m. Read More

J Heart Lung Transplant 2020 Apr 30;39(4S):S447-S448. Epub 2020 Mar 30.

Cardiology, Odense University Hospital, Odense C, Denmark.

Purpose: To compare the effect of equipotent dosages of epinephrine, dopamine, norepinephrine, and phenylephrine on left ventricular (LV) work and end-organ perfusion in a porcine model of profound ischemic cardiogenic shock (CS) supported by Impella CP.

Methods: CS was induced in 10 pigs by stepwise intracoronary injection of microspheres. After CS was induced and Impella CP support initiated, animals were treated in a blinded crossover design with norepinephrine (0. Read More

BJU Int 2020 May 26. Epub 2020 May 26.

Department of Urology, San Giovanni Battista Hospital, Città della Salute e della Scienza and University of Turin, Turin, Italy.

Background: No large multicentre prospective studies ever addressed the outcomes of mpMRI targeted fusion transperineal biopsy (TPFBx) under local anesthesia (LA). The debate upon best biopsy modality is still open.

Patients And Methods: We prospectively screened for inclusion 1,327 men with a positive mpMRI undergoing TPFBx (targeted cores and systematic cores) under LA, at two tertiary referral institutions, from Sep2016 to May2019. Read More

J Chromatogr Sci 2020 May 25. Epub 2020 May 25.

Department of Hand Surgery, China-Japan Union Hospital, Jilin University, Xiantai Street 126, Changchun 130033, P.R. China.

An ultrasound-assisted ionic liquid (IL) salting-out microextraction system was developed and applied for the extraction of quinolone antibiotics from urine. A precipitate was formed from the salt and IL, and it acted as the sorbent for the analytes. The precipitate containing the analyte was separated by filtration, redissolved, and the solution then was evaporated. Read More

Med Leg J 2020 May 21:25817220923653. Epub 2020 May 21.

Department of Anaesthesia, PGIMER, Chandigarh, India.

Hunger strike is a protest where an informed person refuses essential nourishment with the intention of accomplishing a specific goal. Hunger strikes conflict with medical, ethical, humanitarian and legal values. A multidisciplinary approach is important when dealing with hunger strike patients. Read More

BMC Oral Health 2020 May 20;20(1):149. Epub 2020 May 20.

Epidemiology and Biostatistics Unit, Department of Statistics, College of Sciences, Eritrean Institute of Technology, MaiNefhi, Eritrea.

Background: Oral care is a fundamental nursing practice that has a great impact on patient well-being and general health during hospitalization. Nurses are responsible for providing oral care in the hospital, however, they usually implement it unsatisfactorily due to inadequate resources, lack of standard protocol, time shortage and ineffective training. The aim of the study was, therefore, to assess nurses' barriers to quality oral care practice at a generalized hospital. Read More

Anasthesiol Intensivmed Notfallmed Schmerzther 2020 May 20;55(5):289-299. Epub 2020 May 20.

Drug interactions cause numerous hospital admissions and even death. Administration of multiple therapeutic drugs increases the risk of relevant interactions. Pharmacologist consultation and also IT-based drug-interaction examination focus on this risk and may improve the safety and quality of the medical therapy. Read More

J Sex Med 2020 May 16. Epub 2020 May 16.

Department of Plastic, Reconstructive and Hand Surgery, Amsterdam UMC, location VUMC, Amsterdam, The Netherlands.

Background: Penile inversion vaginoplasty is the surgical gold standard for genital gender-affirmative surgery in transgender women. However, there is an increase of attention for gender-confirming vulvoplasty (GCV), in which no neovaginal cavity is created.

Aim: To describe underlying motives and surgical outcomes of GCV in transgender women. Read More

J Cardiothorac Surg 2020 May 13;15(1):92. Epub 2020 May 13.

Department of Cardiovascular Surgery, Guangdong Cardiovascular Institute, Guangdong Provincial Key Laboratory of South China Structural Heart Disease, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, China.

Background: Certain pregnant women suffer from cardiac pathology,and a few of them need cardiac operations under cardiopulmonary bypass during pregnancy. Feto-neonatal and maternal outcomes have not been sufficiently described.

Methods: We conducted a retrospective review of 22 cases of women undergoing cardiac operations under cardiopulmonary bypass during pregnancy in our hospital from Jan. Read More

BMC Health Serv Res 2020 May 13;20(1):421. Epub 2020 May 13.

Department of Anesthesiology, International University of Health and Welfare, Mita Hospital, Tokyo, Japan.

Background: The indications for general anesthesia (GA) in obstetric settings, which are determined in consideration of maternal and fetal outcome, could be affected by local patterns of clinical practice grounded in unique situations and circumstances that vary among medical institutions. Although the use of GA for cesarean delivery has become less common with more frequent adoption of neuraxial anesthesia, GA was previously chosen for pregnancy with placenta previa at our institution in case of unexpected massive hemorrhage. However, the situation has been gradually changing since formation of a team dedicated to obstetric anesthesia practice. Read More

Paediatr Anaesth 2020 May 12. Epub 2020 May 12.

Sheffield Children's Hospital NHS Trust, Sheffield, UK.

Exposure to environmental tobacco smoke (ETS), also known as passive or second-hand smoking, describes the inhalation of the products of burnt tobacco. This article describes the scale of the population of children exposed to ETS and the risks to their general and their peri-operative health. We explore the concept of a "teachable moment" in peri-operative medicine;an ideal opportunity to deliver a public health intervention at a time where families feel motivated to make a behavioural change. Read More

J Pregnancy 2020 6;2020:5986269. Epub 2020 Jan 6.

Addis Ababa University School of Anesthesia, Addis Ababa, Ethiopia.

Background: Newborns can be assessed clinically using the Apgar score test to quickly and summarily assess the health of newborn physical condition immediately after delivery and to determine any immediate need for extra medical or emergency care. This study is aimed at assessing factors associated with Apgar score among newborns delivered by cesarean sections and factors associated with Apgar score.

Method: Institutional-based cohort study design was conducted. Read More

Physiol Behav 2020 May 6;222:112942. Epub 2020 May 6.

Veterinary Diagnostics and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, 1809 South Riverside Drive, Ames, IA, United States. Electronic address:

Cautery disbudding of goat kids causes thermal burns and tissue destruction, which results in acute and post-operative pain and negatively affects animal welfare. The objectives of this study were to evaluate acute cortisol concentrations and behavioral responses associated with (1) injecting a lidocaine ring block prior to cautery disbudding and comparing this to saline injections and (2) pain mitigation strategies (lidocaine ring block, topical eutectic mixture of local anesthetics (EMLA) cream, oral meloxicam) on cautery disbudded dairy goat kids. Sixty doe kids were allocated to one of six treatments: (1) disbudding without pain relief (DB), (2) a ring block using 1% lidocaine (DBLA) 20 min before disbudding, (3) saline injection (DBSA) 20 min before disbudding, (4) oral meloxicam 60 min before disbudding (DBMEL), (5) EMLA cream rubbed into the buds 60 min before disbudding (DBEM) and (6) handled but not disbudded (HAND). Read More

Hand Surg Rehabil 2020 May 4. Epub 2020 May 4.

Department of General and Hand Surgery, Pomeranian Medical University in Szczecin, ul. Unii Lubelskiej 1, 71-252 Szczecin, Poland. Electronic address:

The Levine questionnaire is commonly used to assess the treatment outcomes of carpal tunnel syndrome (CTS). However, specific items in this questionnaire do not address symptoms or impairment in each hand separately. One concern is that patients with unilateral disease would experience greater improvement as a result of surgery than those with bilateral who have only one hand treated. Read More

J Craniofac Surg 2020 May 4. Epub 2020 May 4.

Yeni Yüzyil University, Health Occupation High-School Audiometry.

Aim: The prominent ear is the most common congenital deformity of the external ear. Otoplasty is performed to correct the appearance of the prominent ear. This study was planned to compare the analgesic and anesthetic effects of local nerve blockade and local infiltration anesthesia in the otoplasties. Read More

Front Med 2020 May 4. Epub 2020 May 4.

Department of Anesthesiology, Peking University Third Hospital, Beijing, 100191, China.

Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2), has caused a global pandemic in only 3 months. In addition to major respiratory distress, characteristic neurological manifestations are also described, indicating that SARS-CoV-2 may be an underestimated opportunistic pathogen of the brain. Based on previous studies of neuroinvasive human respiratory coronaviruses, it is proposed that after physical contact with the nasal mucosa, laryngopharynx, trachea, lower respiratory tract, alveoli epithelium, or gastrointestinal mucosa, SARS-CoV-2 can induce intrinsic and innate immune responses in the host involving increased cytokine release, tissue damage, and high neurosusceptibility to COVID-19, especially in the hypoxic conditions caused by lung injury. Read More

Indian J Anaesth 2020 Apr 28;64(4):267-274. Epub 2020 Mar 28.

Department of Anaesthesiology, Critical Care and Emergency Medicine, Narmada Trauma Center, Bhopal, Madhya Pradesh, India.

World Health Organization (WHO) declared novel coronavirus outbreak a "pandemic" on March 11, 2020. India has already reached Stage 2 (local transmission) and the Indian Government, in collaboration with the Indian Council of Medical Research (ICMR), is taking all necessary steps to halt the community transmission(Stage 3). Anaesthesiologists and intensivists around the globe are making untiring efforts akin to soldiers at the final frontier during war. Read More

BMC Anesthesiol 2020 May 2;20(1):101. Epub 2020 May 2.

Department of Anesthesiology, the First Affiliated Hospital, Wenzhou Medical University, Shangcai village, Nanbaixiang town, Ouhai District, Wenzhou City, 325000, Zhejiang Province, China.

Background: Butorphanol, a synthetic opioid partial agonist analgesic, has been widely used to control perioperative pain. However, the ideal dose and availability of butorphanol for gastrointestinal (GI) endoscopy are not well known. The aim of this study was to evaluated the 95% effective dose (ED) of butorphanol and sufentanil in GI endoscopy and compared their clinical efficacy, especially regarding the recovery time. Read More

Zhongguo Gu Shang 2020 Apr;33(4):363-7

Hand Anesthesiology Department, Changping District Integrated Traditional Chinese and Western Medicine Hospital, Beijing 102208, China.

Objective: To evaluate the effect of femoral and sciatic nerve block in total knee replacement of elderly patients under general anesthesia.

Methods: From July 2017 to July 2019, 60 patients with unilateral total knee replacement were selected, including 35 males and 25 females; aged 66 to 74(70.2±10. Read More

J Nippon Med Sch 2020 Apr 30. Epub 2020 Apr 30.

Department of Orthopaedic Surgery, Nippon Medical School.

This review aimed to clarify the following aspects of tenosynovial giant cell tumors (TSGCTs): the use of multiple names, the complex relationship between the tumor growth pattern and location, the high postoperative recurrence rates, local invasiveness, and the use of non-surgical therapy with molecular targeted drugs, as well as to discuss the currently available best treatments. This tumor has been called by various names in the past, but it is in the direction of being unified to TSGCT. TSGCT is classified into the localized and diffuse types according to the growth characteristics. Read More

J Intern Med 2020 Apr 29. Epub 2020 Apr 29.

Unit of Anaesthesia, Intensive Care and Pain Management, Department of Medicine, Campus Bio Medico University and Teaching Hospital, Rome, Italy.

Severe acute respiratory syndrome coronavirus (SARS-CoV)-2, a novel coronavirus from the same family as SARS-CoV and Middle East respiratory syndrome coronavirus, has spread worldwide leading the World Health Organization to declare a pandemic. The disease caused by SARS-CoV-2, coronavirus disease 2019 (COVID-19), presents flu-like symptoms which can become serious in high-risk individuals. Here, we provide an overview of the known clinical features and treatment options for COVID-19. Read More

Anaesthesist 2020 Apr 28. Epub 2020 Apr 28.

Universitätsklinik für Anästhesiologie, Intensiv‑, Palliativ- und Schmerzmedizin, BG Universitätsklinikum Bergmannsheil GmbH der Ruhr Universität Bochum, Bochum, Deutschland.

Background: The incorporation into the routine operating procedure of patients with small but acute hand and forearm injuries requiring surgery who present in the emergency admission department, represents a challenge due to limited resources. The prompt treatment in the emergency admission department represents an alternative. This article retrospectively reports the authors' experiences with a treatment algorithm in which emergency patients were treated by ultrasound-guided axillary brachial plexus blocks (ABPB) and surgery carried out in the emergency department without further anesthesia attendance. Read More

J Foot Ankle Surg 2020 Apr 25. Epub 2020 Apr 25.

Department of Hand Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.

Dorsal dislocation of the interphalangeal joint of the great toe is quite rare. Closed reduction is often attempted in the emergency setting, but this measure is seldom successful because of invagination of the sesamoid-plantar plate complex into the interphalangeal space. Generally, open reduction is indicated when closed reduction fails. Read More

Kurume Med J 2020 Apr 24. Epub 2020 Apr 24.

Department of Orthopaedics and Traumatology, "251" Hellenic Air Force General Hospital of Athens.

Anterior shoulder dislocations following an epileptic event are considered rare. An extremely rare case of a 41 year old female suffering from bilateral anterior shoulder dislocation with concomitant greater tuberosities fractures after an epileptic seizure is presented. The patient presented to the out-patient orthopaedic clinic due to persistent pain and restriction of shoulders movement, 4 weeks after an epileptic seizure. Read More

BMC Health Serv Res 2020 Apr 25;20(1):353. Epub 2020 Apr 25.

Discipline of General Practice, School of Medicine, National University of Ireland Galway, Co. Galway, Ireland.

Background: Improving hand hygiene (HH) compliance is one of the most important, but elusive, goals of infection control. The purpose of this study was to use the capability (C), opportunity (O), motivation (M), and behaviour (B; COM-B) model and the theoretical domains framework (TDF) to gain an understanding of the barriers and enablers of HH behaviours in an intensive care unit (ICU) in order to identify specific interventions to improve HH compliance.

Methods: A semi-structured interview schedule was developed based upon the COM-B model. Read More

Surg Radiol Anat 2020 Apr 24. Epub 2020 Apr 24.

Department of Anatomy, Second Faculty of Medicine, Charles University, V Úvalu 84, Motol, 150 06, Prague, Czech Republic.

Purpose: The variability of the recurrent branch (RB) of the median nerve lends itself to an increased risk of injury when performing the minimally invasive approach for carpal tunnel release without its direct visualization. This risk is less so when it is released via the more invasive open approach as the RB can be easily identified, but the drawback is that of longer postoperative patient recovery time. Therefore, performing these releases via the less invasive approach should be more favorable for patients providing it could be done safely. Read More

Plast Reconstr Surg 2020 May;145(5):1197-1203

Ankara, Turkey From the Department of Orthopaedics and Traumatology, and the Department of Anesthesiology and Reanimation, University of Health Sciences Turkey, Diskapi Yildirim Beyazit Training and Research Hospital.

Background: The authors conducted a prospective study to compare patients' intraoperative experience of open carpal tunnel release under "wide awake, local anesthesia, no tourniquet" (WALANT) on the one hand and intravenous regional anesthesia on the other. The authors hypothesized that WALANT would offer a better intraoperative experience than intravenous regional anesthesia.

Methods: Twenty-four patients with bilateral carpal tunnel syndrome had one hand operated on using WALANT and the contralateral hand with the intravenous regional anesthesia method. Read More

Climacteric 2020 Apr 22:1-5. Epub 2020 Apr 22.

Department of Obstetrics and Gynaecology, Royal North Shore Hospital School, Saint Leonards, NSW, Australia.

Hysteroscopy and anesthesia have come a long way in the last 150 years. While traditionally performed in the operating theater under general anesthesia, the alternative approach - so-called 'office' hysteroscopy - has gained popularity in recent years. Supporters of this modality cite the 'see and treat' capabilities, avoidance of anesthesia, more rapid turn-around time, and favorable economics as advantages. Read More

Ann Burns Fire Disasters 2019 Sep;32(3):216-221

Lebanese Geitaoui Hospital, Beirut, Lebanon.

Burn injuries are serious lesions requiring specialized medical care, and are associated with prolonged length of hospital stay (LOS). This study aims to elucidate the epidemiological and clinical factors affecting the LOS of pediatric and adult patients with burn wounds. A single-centre retrospective study was conducted at the Hopital Libanais Geitawi Burn Centre in Lebanon. Read More

Pediatrics 2020 May 20;145(5). Epub 2020 Apr 20.

Department of Surgery, University of Louisville, Louisville, Kentucky.

Surgical procedures are performed in the United States in a wide variety of clinical settings and with variation in clinical outcomes. In May 2012, the Task Force for Children's Surgical Care, an ad hoc multidisciplinary group comprising physicians representing specialties relevant to pediatric perioperative care, was convened to generate recommendations to optimize the delivery of children's surgical care. This group generated a white paper detailing the consensus opinions of the involved experts. Read More

Medicine (Baltimore) 2020 Apr;99(16):e19733

Department of Anesthesiology.

Rationale: Becker muscular dystrophy (BMD) and Duchenne muscular dystrophy (DMD) are progressive neuromuscular disorders caused by mutations in the dystrophin gene. The management of anesthesia in patients with BMD is complicated because they are highly sensitive to the conventional anesthetics such as volatile anesthetics and muscle relaxants. It is reported that anesthesia in patients with DMD is associated with several complications. Read More

BMC Anesthesiol 2020 Apr 18;20(1):86. Epub 2020 Apr 18.

Department of Anesthesiology, Pain and Perioperative Medicine, The First Affiliated Hospital of Zhengzhou University, No.1 Jianshe East Road, Zhengzhou, 450052, China.

Background: Postoperative pain is the most prominent concern among surgical patients. It has previously been reported that venous cannulation-induced pain (VCP) can be used to predict postoperative pain after laparoscopic cholecystectomy within 90 mins in the recovery room. Its potential in predicting postoperative pain in patients with patient-controlled intravenous analgesia (PCIA) is worth establishing. Read More

Eur J Trauma Emerg Surg 2020 Apr 17. Epub 2020 Apr 17.

Department of Trauma, Hand, and Reconstructive Surgery, University Hospital Frankfurt, Frankfurt, Germany.

A series of recommendations regarding hospital perioperative preparation for the COVID-19 pandemic were compiled to inform surgeons worldwide on how to provide emergency surgery and trauma care during enduring times.The recommendations are divided into eight domains: (1) General recommendation for surgical services; (2) Emergency Surgery for critically ill COVID-19 positive or suspected patients -Preoperative planning and case selection; (3) Operating Room setup; (4) patient transport to the OR; (5) Surgical staff preparation; (6) Anesthesia considerations; (7) Surgical approach; and (8) Case Completion.The European Society of Emergency Surgery board endorsed these recommendations. Read More

Ann Thorac Surg 2020 Apr 14. Epub 2020 Apr 14.

Department of Thoracic and Vascular Surgery and Department of Medical and Health Sciences, Linköping University, Linköping, Sweden.

Background: This study was performed to develop and validate a cardiac surgical intensive care risk adjustment model for mixed cardiac surgery based on a few preoperative laboratory tests, extracorporeal circulation time, and measurements at arrival to the intensive care unit.

Methods: This was a retrospective study of admissions to 5 cardiac surgical intensive care units in Sweden that submitted data to the Swedish Intensive Care Registry. Admissions from 2008 to 2014 (n = 21,450) were used for model development, whereas admissions from 2015 to 2016 (n = 6463) were used for validation. Read More

J Clin Endocrinol Metab 2020 Apr 17. Epub 2020 Apr 17.

Department of Medicine, Austin Health, Heidelberg, Victoria, Australia.

Intro: Sodium glucose cotransporter 2 inhibitors (SGLT2i) have emerged as an important class of blood glucose lowering medications due to cardiovascular, metabolic and renal benefits. However, there is a small but significant risk of diabetic ketoacidosis (DKA) associated with their use.

Methods: A literature search was conducted in Ovid MEDLINE and Embase to July 2019 using variants on the key search terms sodium-glucose cotransporter 2, diabetic ketoacidosis and type 2 diabetes. Read More

J Intensive Care Soc 2020 Feb 12;21(1):2-6. Epub 2018 Jul 12.

Department of Anaesthesia and Intensive Care Medicine, Frimley Health Foundation Trust, Wexham Park Hospital, Slough, UK.

All decisions made by doctors have a moral dimension. When a moral judgement demands a different course of action to one that represents the usual practice, many doctors do struggle. The inability to embrace such decisions can represent moral negligence, as often the consequence is greater suffering for the individual in question or loss of utility for the population. Read More

Eur J Dent Educ 2020 Apr 13. Epub 2020 Apr 13.

School of Dentistry, Universidad Veracruzana, Rio Blanco, México.

Introduction: We compared the motor learning, self-confidence whilst performing an anaesthesia technique and the perception of confidence between a group of students trained (G1) with two distinct dental anaesthesia simulation models (DASM) and a group of students (G2) not trained with DASM.

Materials And Methods: The G1 students (n = 22) were trained with a learning protocol including a DASM for simulating a puncture and a DASM for simulating an injection of dental anaesthesia. The G2 students (n = 22) received no such training. Read More

Anesth Pain Med 2019 Dec 1;9(6):e92695. Epub 2019 Dec 1.

Department of Anesthesiology, Pain Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

Background: Regional anesthesia provides safe anesthesia for upper extremity surgery. Axillary plexus block approach for hand and forearm surgery is commonly used. The use of adjuvants in combination with local anesthetics for peripheral nerve blocks enhances the quality and duration of anesthesia and postoperative analgesia. Read More

J Hand Surg Eur Vol 2020 Apr 11:1753193420916418. Epub 2020 Apr 11.

Stroke Research Group department of clinical Neurosciences, University of Cambridge, Cambridge, UK.

Surgical fixation of distal radius fractures under local anaesthesia with the patient wide awake allows an intraoperative testing of the fixation stability under active mobilization. We evaluated the feasibility and clinical results of this technique in 45 patients prospectively in two matched comparable groups: wide-awake local anaesthesia no tourniquet and loco-regional anaesthesia. We found that the pain scores during the anaesthetic administration and the surgical procedure were similar in two groups. Read More

Ann Card Anaesth 2020 Apr-Jun;23(2):161-164

Department of Anesthesia and Intensive Care, Sakurabashi-Watanabe Hospital, 2-4-32 Umeda, Kita-ku,Osaka, Japan.

Background: Prior experience may be important for successful placement of a pulmonary artery catheter (PAC). However, there is no report about the minimum number of the placement to reach acceptable technique for the catheter placement during residency.

Aims: This study was designed to examine quality of the catheter placement and to assess the effect of prior experience. Read More

Hand Surg Rehabil 2020 Apr 1. Epub 2020 Apr 1.

Orthopedic resident, Faculty of medicine and pharmacy of Agadir Agadir, Morroco.

J Hand Surg Am 2020 Mar 31. Epub 2020 Mar 31.

Division of Plastic and Reconstructive Surgery. Electronic address:

Purpose: Replant survival rates have reportedly declined over the past decade. Although this problem is multifactorial, 1 potential solution may include the development of a relevant teaching model. The development of an in vivo animal model that can be used for surgical training could enhance surgeon and resident experience and potentially improve outcomes. Read More

BMC Bioinformatics 2020 Apr 3;21(1):132. Epub 2020 Apr 3.

Department of Bioinformatics, University of Würzburg, 97074, Würzburg, Germany.

Background: Processing and analysis of DNA sequences obtained from next-generation sequencing (NGS) face some difficulties in terms of the correct prediction of DNA sequencing outcomes without the implementation of bioinformatics approaches. However, algorithms based on NGS perform inefficiently due to the generation of long DNA fragments, the difficulty of assembling them and the complexity of the used genomes. On the other hand, the Sanger DNA sequencing method is still considered to be the most reliable; it is a reliable choice for virtual modeling to build all possible consensus sequences from smaller DNA fragments. Read More

Br J Sports Med 2020 Apr 2. Epub 2020 Apr 2.

Faculty of Medicine and Health Technology; Department of Orthopaedics and Traumatology, Tampere University Hospital, Tampere University, Tampere, Pirkanmaa, Finland.

Objectives: To assess the rates and secular trends of different joint arthroscopies-shoulder, elbow, wrist, hip, knee and ankle-in Finland between 1997 and 2016.

Design: Retrospective nationwide registry study.

Participants: All adults in Finland with any arthroscopic intervention procedure code for knee, shoulder, ankle, wrist, elbow or hip arthroscopy between 1 January 1997 and 31 December 2016 were included. Read More