Search Our Scientific Publications & Authors

Hand (N Y) 2019 Mar 17:1558944719836237. Epub 2019 Mar 17.

1 The Ohio State University Wexner Medical Center, Columbus, USA.

Purpose: Carpal tunnel syndrome is a common disease treated operatively. During the operation, the patient may be wide-awake or sedated. The current literature has only compared separate cohorts. Read More

J Palliat Care 2019 Mar 14:825859719833659. Epub 2019 Mar 14.

20 Palliative Care Unit, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Meldola, Italy.

This paper is aimed at focusing on the writings and the experience of the Hospice movemente Founder, Dame Cicely Saunders. The in-depth analysis carried out had the objective of verifying if "the way" of Cicely to understand, live and propose palliative care was still current and "beautiful", so that we can nowadays refer to her fascinating "Original Palliative Care". With "beauty" we mean, on the one hand, a way able to allow a personal path of research of the meaning of the disease and of the care, both for those who care and for those who are cared for. Read More

Plast Surg (Oakv) 2019 Feb 3;27(1):10-13. Epub 2018 Oct 3.

Faculty of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada.

Dr Michael Bell was born in Kingston, Ontario, on October 14, 1944. He was always a curious child who exhibited a tendency toward innovation and experimentation. Dr Bell was accepted into the MD program at the University of Toronto graduating in 1969 before completing his plastic surgery residency there. Read More

J Orthop Surg (Hong Kong) 2019 Jan-Apr;27(1):2309499019833002

Hand and Microsurgery Unit, Department of Orthopedics, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.

Background:: Trigger finger release utilizing wide-awake local anesthesia no tourniquet (WALANT) usage in extremity surgery is not widely used in our setting due to the possibility of necrosis. Usage of a tourniquet is generally acceptable for providing surgical field hemostasis. We evaluate hemostasis score, surgical field visibility, onset and duration of anesthesia, pain score, and the duration of surgery and potential side effects of WALANT. Read More

J Mot Behav 2019 Mar 8:1-13. Epub 2019 Mar 8.

a Department of Physical Therapy, College of Staten Island , City University of New York , Staten Island , NY , USA .

The present study investigates the effect of sensory deprivation of the index and middle finger on motor function of all digits during maximal voluntary force production tasks. A total of 27 subjects performed maximal isometric pressing tasks by using different instructed finger combinations. Subjects completed the same tasks in two visits: a control visit when they had normal sensory feedback in all fingers, and an anesthesia visit when digital nerve blocks were performed on their right index and middle fingers. Read More

Iran J Allergy Asthma Immunol 2019 Feb;18(1):100-107

Department of Immunology, Iran University of Medical Sciences, Tehran, Iran.

Systemic sclerosis is a female predominant, a fibrotic autoimmune disease in which disturbance in tissue homeostasis and cell turnover including cell apoptosis are central events in pathogenesis. Sex hormones are known as the important players in sexual dimorphism of autoimmune diseases and in tissue homeostasis. Progesterone influences autoimmune disease via its immunomodulatory effect or by its direct action on parenchymal cell function. Read More

Intensive Care Med 2019 Mar 8. Epub 2019 Mar 8.

Department of Neurology, Columbia-Presbyterian Medical Center, New York, NY, USA.

Purpose: Functional outcomes vary between centers after out-of-hospital cardiac arrest (OHCA) and are partially explained by pre-existing health status and arrest characteristics, while the effects of in-hospital treatments on functional outcome are less understood. We examined variation in functional outcomes by center after adjusting for patient- and arrest-specific characteristics and evaluated how in-hospital management differs between high- and low-performing centers.

Methods: Analysis of observational registry data within the International Cardiac Arrest Registry was used to perform a hierarchical model of center-specific risk standardized rates for good outcome, adjusted for demographics, pre-existing functional status, and arrest-related factors with treatment center as a random effect variable. Read More

Ann Chir Plast Esthet 2018 Dec 5. Epub 2018 Dec 5.

Department of Plastic and Reconstructive Surgery, Centre Hospitalier de l'Université de Montréal (CHUM), 850, Rue Saint-Denis, Montréal, QC H2X 0A9, Canada. Electronic address:

Introduction: Despite positive outcomes reported in the literature, some surgeons remain reluctant to the systematic use of venous couplers in free flap tissue transfer. In our institution, the use of the coupler devices for venous anastomosis in free flap breast reconstruction has yet to be adopted by all surgeons. The purpose of the study was to compare postoperative outcomes of coupler-assisted venous anastomoses with hand-sewn techniques in free flap breast reconstruction. Read More

Resuscitation 2019 Mar 2. Epub 2019 Mar 2.

Predictive Analytics and Comparative Effectiveness (PACE) Center, Institute for Clinical Research and Health Policy Studies (ICRHPS), Tufts Medical Center, 800 Washington St. Boston, MA, USA.

Aim: "Early" withdrawal of life support therapies (eWLST) within the first 3 calendar days after resuscitation from cardiac arrest (CA) is discouraged. We evaluated a prospective multicenter registry of patients admitted to hospitals after resuscitation from CA to determine predictors of eWLST and estimate its impact on outcomes.

Methods: CA survivors enrolled from 2012-2017 in the International Cardiac Arrest Registry (INTCAR) were included. Read More

Anesthesiology 2019 Mar 1. Epub 2019 Mar 1.

From the Department of Anesthesiology, University of Wisconsin School of Medicine and Public Health, William S. Middleton Memorial Veterans Hospital, Madison, Wisconsin.

This fourth and last installment of my history of basic airway management discusses the current (i.e., "modern") era of anesthesia and resuscitation, from 1960 to the present. Read More

Anaesthesiol Intensive Ther 2019 Mar 4. Epub 2019 Mar 4.

Kamakura Hospital, 3-1-8, Hase, 248-0016 Kamakura, Japan.

Background: The purpose of this study was to compare the analgesic effect between intravenous regional anesthesia (IVRA) and supraclavicular block in forearm surgery.

Methods: Eighty patients aged 30 to 70 years for forearm surgery were divided into Supraclavicular group and IVRA group. Supraclavicular block was performed with 1% lidocaine 20 mL. Read More

Cont Lens Anterior Eye 2019 Feb 26. Epub 2019 Feb 26.

Department of Medical Surgical Nursing, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Purpose: The present investigation was done to assess the status of tear film and corneal topography in individuals with long-term exposure to X-ray.

Method: This historical cohort study was carried out to compare the lacrimal and corneal findings between radiographers (n = 126) and non-radiographers (n = 172). Radiographers included individuals with at least 5 years of experience in radiography while subjects in the control group had no history of exposure to X-ray. Read More

Plast Reconstr Surg 2019 Mar;143(3):800-810

Dayton, Ohio; and Rochester, Minn. From the Department of Orthopedic Surgery, Wright-Patterson Air Force Base; and the Division of Hand Surgery, Department of Orthopedic Surgery, Mayo Clinic.

Most unstable metacarpal and phalangeal fractures for which operative treatment is indicated can be reduced and stabilized with either open or closed techniques using local anesthetic with epinephrine instead of intravenous sedation or general anesthesia. With the patient wide-awake during surgery, the hand can be taken through active range of motion to assess fracture stability. In this article, the authors review the rationale and technique for wide-awake, local anesthesia, no tourniquet surgery in the treatment of phalangeal and metacarpal fractures and impart pearls to optimize the patient experience and illustrate common fixation techniques using percutaneous Kirschner wires. Read More

J Educ Health Promot 2019 29;8. Epub 2019 Jan 29.

Department of Nursery, Institute of Health Sciences, Hasan Kalyoncu University, Gaziantep, Turkey.

Purpose: Postpartum period is a critical interval in which the woman is under risk for psychiatric disorders including postpartum depression (PD). This study was performed to investigate the impact of the mode of delivery on the occurrence of PD in primiparous mothers.

Materials And Methods: This correlational study was performed on 244 primiparous women (aged 15-49 years) in 17 primary health-care centers. Read More

J Pediatr Surg 2019 Feb 12. Epub 2019 Feb 12.

Unit of Pediatric Surgery, Giannina Gaslini Institute, Genoa, Italy.

Introduction: The association of Hirschsprung disease (HSCR) and Down Syndrome (DS) is not uncommon (HSCR+DS). This paper aims at reporting the results of a 24-year series focusing on surgical approach, complications and long term outcome.

Materials And Methods: The notes of all patients admitted with a diagnosis of HSCR+DS have been retrospectively reviewed. Read More

BMC Anesthesiol 2019 Feb 26;19(1):28. Epub 2019 Feb 26.

Maquet Critical Care, AB, Rontgenvagen 2, S-17154, Solna, Sweden.

Background: There is continuing interest among clinicians in the potential for advanced hemodynamic monitoring and "goal directed" intravenous fluid administration guided by minimally-invasive cardiac output measurement to reduce complication rates in high risk patients undergoing major surgery. However, the adoption of the available technologies has been limited, due to cost, complexity and reliability of measurements provided. We review progress in the development of new generation methods for continuous non-invasive monitoring of cardiac output from measurement of carbon dioxide elimination in ventilated patients using the Differential Fick method. Read More

Hand (N Y) 2019 Feb 27:1558944719831333. Epub 2019 Feb 27.

1 New York University Langone Orthopedic Hospital, New York City, USA.

Background: No study exists on preparatory time-from patient's entrance into the operating room to skin incision-and its role in hand surgery operating room inefficiency. The purpose of this study was to investigate the length and variability of preparatory time and assess the relationship between several variables and preparatory time.

Methods: Consecutive upper extremity cases performed for a period of 1 month by hand surgeons were reviewed at 3 surgical sites. Read More

J Clin Monit Comput 2019 Feb 26. Epub 2019 Feb 26.

Anesthesiology Department, CHU UCL Namur, Avenue Dr Gaston Thérasse, 1, 5530, Yvoir, Belgium.

The variability or inaccuracy of acceleromyographic measurements could interfere with the interpretation of the train-of-four (TOF) ratio during neuromuscular block (NMB) recovery. This study evaluated the precision and performance of the Philips Intellivue NMT module (NMT) before (part 1) and after (part 2) several technical upgrades (i.e. Read More

Crit Care 2019 Feb 22;23(1):62. Epub 2019 Feb 22.

Department of Anaesthesia, Critical Care and Pain Medicine, Division of General Anaesthesia and Intensive Care Medicine, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.

There is a high degree of uncertainty regarding optimum care of patients with potential or known intake of oral anticoagulants and traumatic brain injury (TBI). Anticoagulation therapy aggravates the risk of intracerebral hemorrhage but, on the other hand, patients take anticoagulants because of an underlying prothrombotic risk, and this could be increased following trauma. Treatment decisions must be taken with due consideration of both these risks. Read More

Hand (N Y) 2019 Feb 22:1558944718822086. Epub 2019 Feb 22.

1 University Hospital of Verona, Italy.

Background: We want to describe a treatment for advanced Dupuytren disease using a spanning external fixator (EF) applied dorsally to produce progressive extension, followed by collagenase injection.

Methods: Between October 2014 and September 2016, a total of 22 fingers from 18 patients were treated with an EF. The devices were implanted under local anesthesia, and the patients were instructed to gradually extend the hinge to gain a progressive extension. Read More

Hand (N Y) 2019 Feb 21:1558944719828006. Epub 2019 Feb 21.

1 VA Palo Alto Health Care System, Menlo Park, CA, USA.

Background: Carpal tunnel release (CTR) can be performed with a variety of anesthesia techniques. General anesthesia is associated with higher risk profile and increased resource utilization, suggesting it should not be routinely used for CTR. The purpose of this study was to examine the patient factors associated with surgeons' requests for general anesthesia for CTR and the frequency of routine use of general anesthesia by Veterans Health Administration (VHA) surgeons and facilities. Read More

Anaesthesia 2019 Feb 20. Epub 2019 Feb 20.

Nuffield Department of Anaesthetics, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.

A decision by a society to sanction assisted dying in any form should logically go hand-in-hand with defining the acceptable method(s). Assisted dying is legal in several countries and we have reviewed the methods commonly used, contrasting these with an analysis of capital punishment in the USA. We expected that, since a common humane aim is to achieve unconsciousness at the point of death, which then occurs rapidly without pain or distress, there might be a single technique being used. Read More

J Surg Orthop Adv 2018 ;27(4):317-320

Department of Orthopaedic Surgery, Medical University of South Carolina, Charleston, South Carolina.

The purpose of this study was to assess patient preferences in this population with respect to anesthesia for minor hand procedures. This prospective cohort study assessed 183 patients undergoing minor hand surgery to determine their preferences for local-only anesthesia with or without sedation and the reasons for their choices. Fifty-six percent of patients preferred local anesthesia with sedation, 43% preferred local-only anesthesia, and 2% had no preference. Read More

J Neurosurg Anesthesiol 2019 Jan;31(1):125-128

Department of Anesthesiology and Perioperative Medicine, Neurology, and Psychiatry, University of Rochester Medical Center, Rochester, NY.

An important aspect of any research endeavor is engaging various stakeholders to work toward the common goal of pushing knowledge forward about the question at hand. Research into pediatric anesthetic neurotoxicity could benefit greatly from interventions designed to improve the efforts and dedication of government agencies, pharmaceutical companies, research communities, and most importantly, patients. The Pediatric Anesthesia Neurodevelopment Assessment (PANDA) symposium is a biennial meeting where updates in research in the field are presented, and issues relevant to the community are discussed in round table discussions. Read More

J Digit Imaging 2019 Jan 31. Epub 2019 Jan 31.

George W. Woodruff School of Mechanical Engineering, Georgia Institute of Technology, Atlanta, GA, USA.

The effect of percutaneous, surgical, and medical therapies for vascular malformations (VMs) is often difficult to quantify volumetrically using cross-sectional imaging. Volumetric measurement is often estimated with serial, expensive MRI examinations which may require sedation or anesthesia. We aim to explore whether a portable 3D scanning device is capable of rapid, accurate volumetric analysis of pediatric VMs. Read More

Intensive Crit Care Nurs 2019 Feb 5. Epub 2019 Feb 5.

Anesthesia, Intensive Care and Emergency Department, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milano, Italy; Department of Pathophysiology and Transplantation, University of Milan, Milano, Italy. Electronic address:

Background: Careful hand hygiene of healthcare workers is recommended to reduce transmission of pathogenic microorganisms to patients. Mobile phones are commonly used during work shifts and may act as vehicles of pathogens.

Objective: To assess the colonizsation rate of intensive care unit healthcare workers' mobile phones before and after work shifts. Read More

PM R 2019 Feb 7. Epub 2019 Feb 7.

Division of Physical Medicine and Rehabilitation, Department of Medicine, University of Toronto, Toronto.

Background: Carpal tunnel syndrome (CTS) is the most common entrapment mono-neuropathy of the median nerve. In comparison to open surgical and endoscopic carpal tunnel release, a new ultrasound guided hook knife carpal tunnel release (CTR) procedure was reported to have superior results in terms of reduced morbidity and early return to work.

Objective: To evaluate the reproducibility of the hook knife CTR procedure when performed by musculoskeletal ultrasound trained physicians without a prior experience in this technique. Read More

Med Princ Pract 2019 Feb 6. Epub 2019 Feb 6.

Objective: Mandibular third molar extractions are important in oral maxillofacial surgery. Damage to the lingual nerves, although rare, is a possible complication. There are reports of postoperative recovery after lingual nerve repair, but few reports compared subjective and objective assessments of neurosensory function. Read More

Ann Plast Surg 2019 Mar;82(3 Suppl 2):S162-S168

Spaulding Rehabilitation Hospital/Harvard Medical School, Boston, MA.

Introduction: Postburn scarring is common, but the risk factors, natural history, and consequences of such scars are still poorly understood. This study aims to describe the frequency of scar-related morbidity for up to 2 years after injury and to analyze the impact of burn scars on long-term functional, psychosocial, and reintegration outcomes.

Methods: Analysis was conducted on data collected between January 2006 and May 2014 from 960 patients (2440 anatomic burn sites) using the Burn Model System (BMS) database. Read More

Anaesthesiol Intensive Ther 2019 Feb 6. Epub 2019 Feb 6.

Department of Paediatric Anaesthesiology and Critical Care Medicine, Asklepios Kinderklinik Sankt Augustin, German Paediatric Heart Centre, Arnold-Janssen Street 29, 53757 Sankt Augustin, Germany.

To the Editor, Nasotracheal intubation is a widely used technique in anaesthesia management for procedures including oropharyngeal, dental, and maxillofacial surgeries[1-3]. It provides an uninhibited access to the mouth and plays an important role when dealing with difficult airways[4-6]. It is also used in patients with cervical spine instability owing to injury[7] or in patients with a cervical spine fixation owing to a disease or previous operation[8]. Read More

Sci Rep 2019 Feb 4;9(1):1174. Epub 2019 Feb 4.

Department of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

Pediatric patients have large heads and relatively small bodies, making it difficult to perform intubation even in the sniffing position. Therefore, this study was planned on the assumption that hand-assisted elevation and caudad traction of the shoulder (HA-ECTS) would compensate for the laryngoscopic view. In this observational study, 45 pediatric patients aged 0-36 months with an ASA physical status of I-III and scheduled for elective surgery under general anesthesia were enrolled. Read More

Acta Biomed 2018 Dec 20;90(1-S):158-161. Epub 2018 Dec 20.

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Background And Aim Of The Work: Hypothenar Hammer Syndrome is a relatively rare disease process caused by repetitive stress or injury to the hypothenar eminence leading to chronic injury to the ulnar artery. Our study reports an unusual case.

Methods: A 57 years old Plumber presented in April 2016 with a history of constant pain and recurrent paresthesia involving the fingers of the right hand for several months, over the previous 1 year, his hand had become more intolerant of exposure to cold temperatures. Read More

Epilepsy Res 2019 Mar 18;151:7-16. Epub 2019 Jan 18.

A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Finland.

Multi-center preclinical studies can facilitate the discovery of biomarkers of antiepileptogenesis and thus facilitate the diagnosis and treatment development of patients at risk of developing post-traumatic epilepsy. However, these studies are often limited by the difficulty in harmonizing experimental protocols between laboratories. Here, we assess whether the production of traumatic brain injury (TBI) using the lateral fluid-percussion injury (FPI) in adult male Sprague-Dawley rats (12 weeks at the time of injury) was harmonized between three laboratories - located in the University of Eastern Finland (UEF), Monash University in Melbourne, Australia (Melbourne) and The University of California, Los Angeles, USA (UCLA). Read More

Methods Mol Biol 2019 ;1929:679-690

Department of Anaesthesia and Intensive Care, Länssjukhuset Halland, Halmstad, Sweden.

S100B is a calcium-binding protein most abundant in neuronal tissue. It is expressed in glial cells and Schwann cells and exerts both intra- and extracellular effects. Depending on the concentration, secreted S100B exerts either trophic or toxic effects. Read More

J Intensive Care 2019 22;7. Epub 2019 Jan 22.

11Department of Emergency Medicine, Vident Medical Center, East Carolina University Brody School of Medicine, 600 Moye Blvd, Greenville, NC 27834 USA.

Objective: To determine if real-time compression feedback using a non-automated hand-held device improves patient outcomes from in-hospital cardiac arrest (IHCA).

Methods: We conducted a prospective, randomized, controlled, parallel study (no crossover) of patients with IHCA in the mixed medical-surgical intensive care units (ICUs) of eight academic hospitals. Patients received either standard manual chest compressions or compressions performed with real-time feedback using the Cardio First Angel™ (CFA) device. Read More

J Hand Surg Am 2019 Jan 23. Epub 2019 Jan 23.

Department of Orthopaedic Surgery, Surgical Science, Tokai University School of Medicine, Isehara-shi, Kanagawa, Japan.

Injuries to the ulnar collateral ligament (UCL) of the thumb are common and require prompt attention. Diagnostic findings and treatment options differ in acute and chronic injuries of the UCL. Pain and weakness of pinch and grip occur with chronic UCL instability. Read More

World Neurosurg 2019 Jan 24. Epub 2019 Jan 24.

Department of Neurosurgery, University Hospital of Salamanca, Salamanca, Spain.

Objective: Our objective is to define the clinical, radiologic, and technical factors that can condition the emergence of postbiopsy symptomatic intracranial hemorrhage. Based on our findings, we suggest recommendations to improve its usual clinical practice.

Methods: We performed a retrospective study of 407 cases with stereotactic biopsies performed in the last 34 years. Read More

CNS Neurosci Ther 2019 Jan 24. Epub 2019 Jan 24.

Department of Anesthesiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Aims: Anesthesia and surgery can cause delirium-like symptoms postoperatively. Increasing evidence suggests that gut microbiota is a physiological regulator of the brain. Herein, we investigated whether gut microbiota plays a role in postoperative delirium (POD). Read More

Am J Infect Control 2019 Jan 18. Epub 2019 Jan 18.

Duke University School of Nursing, Durham, NC; Duke University Hospital, Durham, NC.

Background: Anesthesia providers commonly cross-contaminate their workspace and subsequently put patients at risk for a health care-acquired infection. The primary objective of this project was to determine if education and implementation of standardized infection control guidelines that address evidence-based best practices would improve compliance with infection control procedures in the anesthesia workspace.

Methods: Patient care-related hand hygiene of nurse anesthetists was observed in 3 areas of anesthesia practice before and 3 weeks and 3 months after staff education, placement of visual reminders, and the implementation of infection control guidelines. Read More

Saudi Pharm J 2019 Jan 7;27(1):126-132. Epub 2018 Sep 7.

Pharmacology, Clinical Pharmacy and Quality Control Laboratory, Faculty of Pharmacy, Saint-Joseph University of Beirut, Lebanon.

Objective: To evaluate treatment adherence to oral glucose lowering drugs (OGLD) and health related quality of life in Lebanese diabetics. Secondary objectives were to examine associations between treatment adherence, quality of life (QOL), treatment satisfaction and illness perception.

Methods: This cross-sectional study, conducted in all districts of Lebanon between August 2016 and April 2017, enrolled 207 adult patients, taking any OGLD. Read More

Anesth Essays Res 2018 Oct-Dec;12(4):843-847

Department of Anaesthesia, M.S. Ramaiah Medical College, Bengaluru, Karnataka, India.

Introduction: Awareness following noxious stimuli like intubation could be as high as 25% compared to postoperative recall. The isolated forearm technique (IFT) allows us to assess consciousness by verbal command to move isolated hand. Hence we conducted study to establish IFT responses following intubation under standard general anaesthesia. Read More

Endocr Metab Immune Disord Drug Targets 2019 Jan 18. Epub 2019 Jan 18.

Ionian Department, University of Bari "Aldo Moro", Bari. Italy.

Background And Objective: Oral cancer is one of the most common malignancies that affect human beings across the world and early detection of oral cancer is believed to reduce the morbidity significantly. Fluorescence diagnosis is emerging as a promising method in the differentiation of cancerous lesions and thus helping in the determination of resolution for the surgical resection of affected area of malignancy very accurately. The aim of this study was to evaluate the usefulness of an autofluorescence hand held device (OralID) to detect oral premalignant lesions. Read More

J Drug Alcohol Res 2018 Jun;7

Department of Pharmacology, University of Tennessee Health Science Center, Memphis, TN 38163, USA.

Approximately half of pregnant women engage in alcohol consumption some time during pregnancy. On the other hand, a small percentage of pregnant women undergo surgery and anesthesia at some time during pregnancy. In emergencies, anesthesia has to be administered to patients who are under alcohol intoxication. Read More

Rev Bras Anestesiol 2019 Jan 14. Epub 2019 Jan 14.

Universidade Estadual Paulista (Unesp), Faculdade de Medicina de Botucatu, Departamento de Anestesiologia, Botucatu, SP, Brasil.

Introduction: The importance and benefits of breastfeeding for the babies and mothers are well established and documented in the literature. However, it is frequent that lactating mothers need to undergo general or spinal anesthesia and, due to the lack of information, many of them interrupt breastfeeding after anesthesia. There are limited data available regarding anesthetics transfer to breast milk. Read More

Anaesthesist 2019 Jan;68(1):3-14

Klinik für Anästhesiologie mit S. op. Intensivmedizin, Charité - Universitätsmedizin Berlin, Campus Virchow-Klinikum, Berlin, Deutschland.

The discovery of the local anaesthetic effect by blocking sodium ion channels was a milestone in anaesthesia but was soon limited by sometimes life-threatening toxic effects of the local anaesthetics. By developing novel local anaesthetics and also by adding so-called adjuvants, attempts have been made to limit these life-threatening events. This article focuses on the historic background and the current state of the use of these adjuvants for regional anaesthesia. Read More

J Biol Regul Homeost Agents 2018 Nov-Dec;32(6 Suppl. 1):57-63

Intensive Unit Care, University of Pisa, Italy.

Hardware removal after surgical treatment fracture is one of the most common procedures in orthopaedic daily activity. A percentage from 14.5 to 21 of total removal involves the ankle joint. Read More

J Clin Monit Comput 2019 Jan 11. Epub 2019 Jan 11.

Department of Acute Medicine, Section Cardiothoracic and Vascular Anesthesia, Cliniques Universitaires Saint Luc, Avenue Hippocrate 10, 1200, Brussels, Belgium.

Studies have associated electroencephalogram (EEG) suppression with postoperative delirium (POD) and postoperative cognitive decline (POCD). Otherwise, improving cerebral tissue oxygen saturation (rScO) seems beneficial. No study has evaluated the impact of EEG suppression and decreased rScO on the incidence of POD and POCD when the intraoperative management of patients is performed with a depth-of-anesthesia (DOA) monitor and a cerebral oximetry. Read More

Medicine (Baltimore) 2019 Jan;98(2):e13940

The Department of Anaesthesia, Second Affiliated Hospital, Jiaxing University, Zhejiang Province, China.

Background: Residual postoperative neuromuscular blockade is an important clinical issue. Neuromuscular monitoring is usually used to evaluate neuromuscular recovery in patients undergoing general anesthesia. However, this procedure is inconvenient and not widely adopted. Read More

BMC Anesthesiol 2019 Jan 10;19(1). Epub 2019 Jan 10.

Department of Anesthesiology and Pain Medicine, CHA Bundang Medical Center, CHA University, 59 Yatap-ro, Bundang-gu, Seongnam-si, Gyeonggi-do, 13496, South Korea.

Background: Several methods have been used to predict difficult tracheal intubation. Among recently suggested methods, the upper lip bite test (ULBT) could serve as a good predictor. Soft tissue and skeletal hard tissue profiles are affected by many factors including ethnicity. Read More