111,060 results match your criteria Hand Anatomy


The Pronephros; a fresh perspective.

Integr Comp Biol 2019 Jan 15. Epub 2019 Jan 15.

Department of Medical Biology, Section Clinical Anatomy & Embryology, Amsterdam UMC, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands. Tel.: +31 20 5665396; Fax: +31 20 6976177.

Contemporary papers and book chapters on nephrology open with the assumption that human kidney development passes through three morphological stages: pronephros, mesonephros and metanephros. Current knowledge of the human pronephros, however, appears to be based on only a hand full of human specimens. The ongoing use of variations in the definition of a pronephros hamper the interpretation of study results. Read More

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https://academic.oup.com/icb/advance-article/doi/10.1093/icb
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http://dx.doi.org/10.1093/icb/icz001DOI Listing
January 2019
1 Read

The Prion 2018 round tables (I): The structure of PrP.

Prion 2019 Jan 15. Epub 2019 Jan 15.

f Department of Biochemistry and Centre for Prions and Protein Folding Diseases , University of Alberta , Edmonton , AB , Canada .

Understanding the structure of PrP is without doubt a sine qua non to understand not only PrP propagation, but also critical features of that process such as the strain phenomenon and transmission barriers. While elucidation of the PrP structure has been full of difficulties, we now have a large amount of structural information that allows us to begin to understand it. This commentary article summarizes a round table that took place within the Prion 2018 meeting held in Santiago de Compostela to discuss the state of the art in this matter. Read More

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http://dx.doi.org/10.1080/19336896.2019.1569450DOI Listing
January 2019

Reverse vascularized bone graft of the lateral distal humerus for non-union of the radial neck fracture: anatomical study and case report.

J Plast Surg Hand Surg 2019 Jan 12:1-5. Epub 2019 Jan 12.

a Department of Orthopaedic Surgery , Nara Medical University , Kashihara , Japan.

A few treatment options for radial neck non-union have been reported, including radial head excision, radial head replacement, and internal fixation with a bone graft. We describe a new treatment for radial neck non-union using a reverse vascularized bone graft of the lateral distal humerus. In the anatomical study, the posterior radial collateral artery (PRCA) was dissected in eight fresh-frozen cadaver arms. Read More

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http://dx.doi.org/10.1080/2000656X.2018.1520122DOI Listing
January 2019

Heritability estimation of 2D:4D finger ratio in a Chuvashian population-based sample.

Am J Hum Biol 2019 Jan 11:e23212. Epub 2019 Jan 11.

Human Population Biology Research Unit, Department of Anatomy and Anthropology, Tel Aviv University, Tel Aviv, Israel.

Objectives: The purpose of this study was to evaluate the familial correlations and heritability of 2D:4D ratio traits using a large population-based sample of ethnically homogeneous pedigrees from Chuvasha and Bashkortostan Autonomies of the Russian Federation.

Methods: We calculated the familial correlations and performed a heritability analysis of 2D:4D ratio traits in a sample of 1541 subjects (803 men and 738 women, mean age 47.78 ± 16. Read More

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http://dx.doi.org/10.1002/ajhb.23212DOI Listing
January 2019

[Senile rheumatoid arthritis associated with rheumatoid lung: a caricatural observation].

Pan Afr Med J 2018 6;30:253. Epub 2018 Aug 6.

Service de Médecine Interne B, Hôpital Charles Nicolle, Université de Tunis El Manar, Faculté de Médecine de Tunis, Tunis, Tunisie.

In the elderly, rheumatoid arthritis is defined by an average age of onset over 60 years. Prognosis mainly depends upon functional capacity, evolutionary stage of the disease, onset or no onset of joint malformations. We report the case of a 70-year old female patient with a history of arterial hypertension, hypothyroidism and Sjögren syndrome diagnosed in 2005. Read More

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http://dx.doi.org/10.11604/pamj.2018.30.253.16372DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307917PMC
January 2019
2 Reads

How Deep Brain Stimulation of the Nucleus Accumbens Affects the Cingulate Gyrus and Vice Versa.

Brain Sci 2019 Jan 4;9(1). Epub 2019 Jan 4.

C.N.S. Alliance Research Group, 14123 Athens, Greece.

The nucleus accumbens (NA) and the cingulate gyrus (CG) are two vital limbic brain structures. They have attracted attention as deep brain stimulation (DBS) targets in the treatment of common refractory psychiatric illness. The primary purpose of this article was to review the current knowledge regarding the way that NA DBS affects the CG and vice versa. Read More

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http://dx.doi.org/10.3390/brainsci9010005DOI Listing
January 2019

A Comprehensive RNA-seq Analysis of Human Bocavirus 1 Transcripts in Infected Human Airway Epithelium.

Viruses 2019 Jan 7;11(1). Epub 2019 Jan 7.

Department of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas City, KS 66160, USA.

Human bocavirus 1 (HBoV1) infects well-differentiated (polarized) human airway epithelium (HAE) cultured at an air-liquid interface (ALI). In the present study, we applied next-generation RNA sequencing to investigate the genome-wide transcription profile of HBoV1, including viral mRNA and small RNA transcripts, in HBoV1-infected HAE cells. We identified novel transcription start and termination sites and confirmed the previously identified splicing events. Read More

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http://dx.doi.org/10.3390/v11010033DOI Listing
January 2019

Mechanism and Prevention of Titanium Particle-Induced Inflammation and Osteolysis.

Front Immunol 2018 18;9:2963. Epub 2018 Dec 18.

Department of Anatomy and Anthropology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

The worldwide number of dental implants and orthopedic prostheses is steadily increasing. Orthopedic implant loosening, in the absence of infection, is mostly attributable to the generation of wear debris. Dental peri-implantitis is characterized by a multifactorial etiology and is the main cause of implant failure. Read More

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http://dx.doi.org/10.3389/fimmu.2018.02963DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305459PMC
December 2018

Imbalance in Renal Vasoactive Enzymes Induced by Mild Hypoxia: Angiotensin-Converting Enzyme Increases While Neutral Endopeptidase Decreases.

Front Physiol 2018 11;9:1791. Epub 2018 Dec 11.

Laboratorio de Neurobiología, Department of Physiology, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile, Santiago, Chile.

Chronic hypoxia has been postulated as one of the mechanisms involved in salt-sensitive hypertension and chronic kidney disease (CKD). Kidneys have a critical role in the regulation of arterial blood pressure through vasoactive systems, such as the renin-angiotensin and the kallikrein-kinin systems, with the angiotensin-converting enzyme (ACE) and kallikrein being two of the main enzymes that produce angiotensin II and bradykinin, respectively. Neutral endopeptidase 24. Read More

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http://dx.doi.org/10.3389/fphys.2018.01791DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297360PMC
December 2018

Individual variations of the human corticospinal tract and its hand-related motor fibers using diffusion MRI tractography.

Brain Imaging Behav 2019 Jan 8. Epub 2019 Jan 8.

Department of Psychiatry, Psychiatry Neuroimaging Laboratory, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

The corticospinal tract (CST) is one of the most well studied tracts in human neuroanatomy. Its clinical significance can be demonstrated in many notable traumatic conditions and diseases such as stroke, spinal cord injury (SCI) or amyotrophic lateral sclerosis (ALS). With the advent of diffusion MRI and tractography the computational representation of the human CST in a 3D model became available. Read More

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http://link.springer.com/10.1007/s11682-018-0006-y
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http://dx.doi.org/10.1007/s11682-018-0006-yDOI Listing
January 2019
2 Reads

The Polish version of the Boston Carpal Tunnel Questionnaire: Associations between patient-rated outcome measures and nerve conduction studies.

J Plast Reconstr Aesthet Surg 2018 Dec 14. Epub 2018 Dec 14.

Department of Neurology, Jagiellonian University Medical College, Kraków, Poland.

Purpose: The aim of this study was to investigate the associations between nerve conduction studies and three commonly used patient-reported outcome measures (Disabilities of the Arm, Shoulder and Hand [DASH], Michigan Hand Outcomes Questionnaire [MHQ], and the Polish version of the Boston Carpal Tunnel Questionnaire [BCTQ]) METHODS: A total of 218 consecutive patients with carpal tunnel syndrome (CTS) completed the BCTQ, MHQ, and DASH questionnaires followed by nerve conduction studies on their first visit to the clinic.

Results: After a 14-day interval, 189 of these patients completed the BCTQ for the second time. The Polish version of the BCTQ was shown to have excellent internal consistency, test-retest reliability, and validity. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S17486815183047
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http://dx.doi.org/10.1016/j.bjps.2018.12.032DOI Listing
December 2018
2 Reads

Flexor tendon repair with a polytetrafluoroethylene (PTFE) suture material.

Arch Orthop Trauma Surg 2019 Jan 4. Epub 2019 Jan 4.

Department of Plastic and Hand Surgery, University of Erlangen Medical Center, Erlangen, Germany.

Background: There is a consensus that after a flexor tendon repair an aggressive rehabilitation protocol with early active motion can improve functional outcome, provided that the combination of material and suturing technique can meet the higher biomechanic demands. Bearing this in mind we evaluated a polytetrafluoroethylene (PTFE) suture (SERAMON, Serag-Wiessner) as a possible material for flexor tendon repair.

Materials And Methods: 40 flexor tendons were harvested from fresh cadaveric upper extremities. Read More

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http://dx.doi.org/10.1007/s00402-018-03105-3DOI Listing
January 2019

Commentary on: Detailed Sonographic Anatomy of Dorsal Hand Augmentation With Hyaluronic Acid and Calcium Hydroxyapatite Fillers.

Authors:
Miles H Graivier

Aesthet Surg J 2019 Jan 4. Epub 2019 Jan 4.

Plastic surgeon in private practice in Alpharetta, GA.

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http://dx.doi.org/10.1093/asj/sjy322DOI Listing
January 2019

Trigger finger secondary to a neglected flexor tendon rupture.

Medicine (Baltimore) 2019 Jan;98(1):e13980

Department of Orthopedic Surgery, Research Institute of Clinical Medicine of Chonbuk National University-Biomedical Research Institute of Chonbuk National University Hospital, Jeonju, Chonbuk, Republic of Korea.

Secondary trigger finger caused by trauma to the hand, especially associated with partial flexor tendon rupture, is not a common condition. Thus, the clinical manifestations of these patients are not well-known. The aim of this study is to present secondary trigger finger caused by a neglected partial flexor tendon rupture including discussion of the mechanism and treatment. Read More

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http://dx.doi.org/10.1097/MD.0000000000013980DOI Listing
January 2019
1 Read

Apatinib with EGFR-TKIs in advanced wild gene-type NSCLC: A case report.

Medicine (Baltimore) 2019 Jan;98(1):e13924

Department of Oncology, Xinjin County People's Hospital.

Rationale: For advanced non-small-cell lung cancer (NSCLC), targeted therapy and chemoradiotherapy are recommended as the first-line treatment. For patients with a performance status (PS) score over 2 and without gene mutation, however, only supportive treatment is provided and survival time is extremely short. We believe that more can be done to improve the patient's survival time and their quality of life. Read More

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http://Insights.ovid.com/crossref?an=00005792-201901040-0004
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http://dx.doi.org/10.1097/MD.0000000000013924DOI Listing
January 2019
9 Reads

[Anatomy and pathobiomechanics of the scaphoid].

Unfallchirurg 2019 Jan 3. Epub 2019 Jan 3.

Klinik für Unfall‑, Hand- und Wiederherstellungschirurgie, Universitätsklinikum Münster, Waldeyerstr. 1, 48149, Münster, Deutschland.

Among the carpal bones the scaphoid (Os scaphoideum) is the most important. The most frequent fracture of the carpus is a fracture of the scaphoid bone. The frequently occurring absence of healing of these fractures as well as unhealed ruptures of the ligament complex between the scaphoid and lunate, lead to the most severe biomechanical and thus the most severe clinical changes of the wrist. Read More

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http://link.springer.com/10.1007/s00113-018-0597-1
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http://dx.doi.org/10.1007/s00113-018-0597-1DOI Listing
January 2019
1 Read

Unconscious Semantic Priming Influences Performance of Visuomotor Tasks Differently but the Effects are Similar in Young and Older Adults.

J Mot Behav 2019 Jan 2:1-7. Epub 2019 Jan 2.

b Institute of Physiology and Anatomy , German Sport University , Köln , Germany.

We examined the effects of semantic priming of attention on two sequentially presented visuomotor tasks, traffic judgments and saccadic adaptation. Priming was accomplished with the scrambled sentence task: participants formed meaningful sentences from a list of words where a word denoting wide attention focus was involved. The results showed that semantic priming influenced positively saccade adaptation (its' benefit increased) while it attenuated visuomotor performance in the traffic task (RT of hand movements increased). Read More

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http://dx.doi.org/10.1080/00222895.2018.1545216DOI Listing
January 2019
1 Read

Persistent Median Artery as an Unusual Finding in the Carpal Tunnel: Its Contribution to the Blood Supply of the Hand and Clinical Significance.

Med Sci Monit 2019 Jan 2;25:32-39. Epub 2019 Jan 2.

Department of Normal and Clinical Anatomy, Interfaculty Chair of Anatomy and Histology, Medical University of Łódź, Łódź, Poland.

BACKGROUND Knowledge of the variable relation of the persistent median artery (PMA) to the median nerve and its contribution to the formation of the superficial palmar arch is of great clinical significance. This study presents a proposal of specific variables which might be introduced to characterize the PMA in the wrist region. MATERIAL AND METHODS One hundred and twenty-five randomly selected, isolated upper limbs fixed in 10% formalin solution were subjected to anatomical dissection. Read More

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http://dx.doi.org/10.12659/MSM.912269DOI Listing
January 2019

Nerve transfer of the anterior interosseous nerve to the thenar branch of the median nerve - an anatomical and histological analysis.

J Plast Reconstr Aesthet Surg 2018 Dec 15. Epub 2018 Dec 15.

Department for Hand, Plastic and Aesthetic Surgery, Ludwig - Maximilian University Munich, Germany.

Objective: Nerve transfer has become a vital method in the reconstruction of hand function. Reconstructing the motor function to the thenar musculature has proven to be difficult and is rarely satisfactory following direct anatomic repair. The aim of this investigation was to describe the anatomic results obtained by transferring the anterior interosseous nerve to the thenar branch of the median nerve and analyze the histomorphometric results. Read More

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http://dx.doi.org/10.1016/j.bjps.2018.12.017DOI Listing
December 2018

Complexities of transcatheter mitral valve replacement (TMVR) and why it is not transcatheter aortic valve replacement (TAVR).

Ann Cardiothorac Surg 2018 Nov;7(6):724-730

Department of Cardiovascular Surgery, Houston Methodist Hospital, Houston, Texas, USA.

Transcatheter mitral valve replacement (TMVR) is currently being investigated as a procedural alternative to surgical mitral valve repair or replacement (SMVR). Early data from first-in-man trials with current devices suggest that TMVR is technically feasible but carries a high mortality. This is substantially different from the early success transcatheter aortic valve replacement (TAVR) has seen and is related to complexities of the mitral valve anatomy, differences in pathology that require mitral valve replacement as well as the impact that mitral valve replacement has on physiology and cardiac function, irrespective of the modality by which the mitral valve is replaced. Read More

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http://dx.doi.org/10.21037/acs.2018.10.06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288216PMC
November 2018
1 Read

Age-Related Variations in Volar Cortical Angle of the Distal Radius.

Hand (N Y) 2018 Dec 31:1558944718820962. Epub 2018 Dec 31.

1 University of Pennsylvania, Philadelphia, USA.

Background: The ideal volar locking plate for the treatment of distal radius fracture should anatomically fit the volar surface of the distal radius. The purpose of this study was to measure the volar cortical angle (VCA) of uninjured adult distal radii to determine how well the VCA matches that of modern volar locking plates and whether variations in the VCA are related to demographic factors.

Methods: A retrospective radiographic analysis of 273 uninjured adult distal radii was performed. Read More

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http://dx.doi.org/10.1177/1558944718820962DOI Listing
December 2018

Unedited microneurosurgery of a large recurrent papillary tumor of the pineal region.

Surg Neurol Int 2018 28;9:234. Epub 2018 Nov 28.

International Center for Neurosurgery, Henan Provincial People's Hospital, Zhengzhou, China.

Background: Papillary tumor of the pineal region (PTPR) is a new entity introduced in the 2007 World Health Organization (WHO) nomenclature to describe a rare grade II-III pineal lesion with epithelial-like papillary architecture and particular immunohistochemical features. PTPR is extremely rare in children. Herein, we present an unedited gross total microsurgical resection of a histologically confirmed WHO grade III PTPR. Read More

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http://dx.doi.org/10.4103/sni.sni_347_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287332PMC
November 2018

Carpal tunnel syndrome caused by synovial osteochondromatosis of the finger flexor tendon: A case report.

Medicine (Baltimore) 2018 Dec;97(52):e13943

Department of Rehabilitation Medicine.

Rationale: Carpal tunnel syndrome (CTS) is the most common peripheral nerve neuropathy resulting from compression of the median nerve as it traverses the carpal tunnel. The pathophysiology of this condition is multifactorial, and majority of cases of CTS are idiopathic. We report cases of CTS caused by synovial osteochondromatosis (SOC), which has rarely been reported. Read More

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http://dx.doi.org/10.1097/MD.0000000000013943DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314781PMC
December 2018

Current Best Peripheral Nerve Transfers for Spinal Cord Injury.

Plast Reconstr Surg 2019 Jan;143(1):184e-198e

St. Louis, Mo. From the Division of Plastic and Reconstructive Surgery, Washington University.

Learning Objectives: After reviewing this article, the participant should be able to: 1. Understand the anatomy and pathophysiology of spinal cord injury and the resulting upper and lower motor neuron syndromes. 2. Read More

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http://dx.doi.org/10.1097/PRS.0000000000005173DOI Listing
January 2019

The Functional Anatomy of the Deep Facial Fat Compartments: A Detailed Imaging-Based Investigation.

Plast Reconstr Surg 2019 Jan;143(1):53-63

Albany and New York, N.Y.; Sacramento, Calif.; Munich, Germany; Zurich, Switzerland; and Salzburg, Austria From the Department of Medical Education, Albany Medical College; private practice; Facial Plastic and Reconstructive Surgery, University of California, Davis Medical Center; the Department for Hand, Plastic and Aesthetic Surgery, Ludwig Maximilian University; the Division of Thoracic Surgery, University Hospital Zurich; and the Department of Radiology, Paracelsus Medical University Salzburg & Nuremberg.

Background: Injection of soft-tissue fillers into the facial fat compartments is frequently performed to ameliorate the signs of facial aging. This study was designed to investigate the functional anatomy of the deep facial fat compartments and to provide information on the effects of injected material in relation to age and gender differences.

Methods: Forty fresh frozen cephalic specimens of 17 male and 23 female Caucasian body donors (mean age, 76. Read More

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http://Insights.ovid.com/crossref?an=00006534-201901000-0001
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http://dx.doi.org/10.1097/PRS.0000000000005080DOI Listing
January 2019
12 Reads

Overexpression of MicroRNA-1 in Prostate Cancer Cells Modulates the Blood Vessel System of an Hen's Egg Test-Chorioallantoic Membrane Model.

In Vivo 2019 Jan-Feb;33(1):41-46

Department of Urology, University Medicine Greifswald, Greifswald, Germany

Background/aim: In prostate cancer (PC), the formation of new blood vessels is stimulated by hypoxic conditions, androgens, and a number of molecular factors including microRNAs. MicroRNA-1 (miR-1) has been characterized in some tumor entities as anti-angiogenic, but this has not yet been investigated in PC.

Materials And Methods: PC cells stably overexpressing miR-1 (LNCaP-miR-1) were incubated on an in vivo hen's egg test-chorioallantoic membrane (HET-CAM) model and compared to maternal LNCaP cells. Read More

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http://dx.doi.org/10.21873/invivo.11436DOI Listing
September 2018

Necrosis of the Fingers and Toes.

N Engl J Med 2018 Dec;379(26):2557

Kochi Medical School, Nankoku, Japan

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http://dx.doi.org/10.1056/NEJMicm1802619DOI Listing
December 2018

Humeral anatomy of the KNM-ER 47000 upper limb skeleton from Ileret, Kenya: Implications for taxonomic identification.

J Hum Evol 2019 Jan 7;126:24-38. Epub 2018 Dec 7.

Department of Human Evolution, Max Planck Institute for Evolutionary Anthropology, Germany; Division of Anthropology, American Museum of Natural History, USA.

KNM-ER 47000 is a fossil hominin upper limb skeleton from the Koobi Fora Formation, Kenya (FwJj14E, Area 1A) that includes portions of the scapula, humerus, ulna, and hand. Dated to ∼1.52 Ma, the skeleton could potentially belong to one of multiple hominin species that have been documented in the Turkana Basin during this time, including Homo habilis, Homo erectus, and Paranthropus boisei. Read More

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http://dx.doi.org/10.1016/j.jhevol.2018.06.011DOI Listing
January 2019

The anatomic location and importance of the tibialis posterior fascicular bundle at the sciatic nerve bifurcation: report of 3 cases.

J Neurosurg 2018 Dec 21:1-7. Epub 2018 Dec 21.

Departments of2Neurosurgery and.

The authors present the cases of 3 patients with severe injuries affecting the peroneal nerve combined with loss of tibialis posterior function (inversion) despite preservation of other tibial nerve function. Loss of tibialis posterior function is problematic, since transfer of the tibialis posterior tendon is arguably the best reconstructive option for foot drop, when available. Analysis of preoperative imaging studies correlated with operative findings and showed that the injuries, while predominantly to the common peroneal nerve, also affected the lateral portion of the tibial nerve/division near the sciatic nerve bifurcation. Read More

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http://dx.doi.org/10.3171/2018.8.JNS181190DOI Listing
December 2018
10 Reads

The p75 neurotrophin receptor in cells of oral mucosal epithelium.

J Biol Regul Homeost Agents 2018 Nov-Dec;32(6):1519-1523

Department of Anatomy, Poznan University of Medical Sciences, Poznan, Poland.

The p75 neurotrophin receptor (p75NTR) can play different roles in cells. This protein can on the one hand act in the regulation of cell growth and survival, while being an apoptosis inducing factor in different contexts. p75NTR regulates cell cycle not only in nerve cells but also in epithelial oral mucosal cells. Read More

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December 2018

Removal of an intraorbital metallic foreign body following double-penetrating ocular injury: A case report.

Medicine (Baltimore) 2018 Dec;97(51):e13790

Department of Ophthalmology, Qilu Hospital.

Rationale: Open eye injury is one of the commonest ophthalmic emergencies, and when accompanied by intraorbital foreign bodies, the condition carries a poor prognosis.

Patient Concerns: A 28-year-old man presented to the emergency department of our hospital complaining of sudden painful loss of vision in the left eye after he hammered an iron plate.

Diagnosis: The ocular examination revealed a 4-mm full thickness scleral laceration with prolapsed uveal tissue, a traumatic cataract. Read More

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http://dx.doi.org/10.1097/MD.0000000000013790DOI Listing
December 2018

Electromagnetic Fields of Mobile Phone Jammer Exposure on Blood Factors in Rats.

J Biomed Phys Eng 2018 Dec 1;8(4):403-408. Epub 2018 Dec 1.

Ionizing and Non-ionizing Radiation Protection Research Center (INIRPRC), Shiraz University of Medical Sciences, Shiraz, Iran.

Background: The increasing demand for using mobile phones has led to increasing mobile phone jammers as well. On the other hand, reports show that exposure to electromagnetic field causes an increase in the incidence of diseases such as leukemia, cancer, depression and failure in pregnancy outcomes; therefore, the aim of this study is to investigate the effects of exposure to electromagnetic fields of mobile phone jammers on blood factors.

Materials And Methods: Thirty male Wistar immature and thirty mature rats were selected randomly and each one was divided into three groups of ten. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280113PMC
December 2018

Surgical Technique for Nasal Cleft Repair.

Ann Plast Surg 2018 Dec 18. Epub 2018 Dec 18.

From the Department of Plastic, Reconstructive, and Hand Surgery, Hadassah University Medical Center, Jerusalem, Israel.

Background: Congenital nasal cleft is a very rare yet challenging deformity to reconstruct. Atypical craniofacial clefts that involve the nasal ala are designated as number 1 and number 2 under the Tessier classification system. These clefts typically present as notches in the medial one-third of either nasal ala and may be accompanied by a malpositioned cartilaginous framework. Read More

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http://dx.doi.org/10.1097/SAP.0000000000001688DOI Listing
December 2018

IDH mutations but not TERTp mutations are associated with seizures in lower-grade gliomas.

Medicine (Baltimore) 2018 Dec;97(50):e13675

Department of Neurosurgery.

Glioma is the most common malignant tumor in the central nervous system (CNS). Lower-grade gliomas (LGG) refer to Grade II and III gliomas. In LGG patients, seizure often appears as an initial symptom and play an important role in clinical performance and quality of life of the patients. Read More

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http://Insights.ovid.com/crossref?an=00005792-201812140-0011
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http://dx.doi.org/10.1097/MD.0000000000013675DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320119PMC
December 2018
1 Read
5.723 Impact Factor

Clinical efficacy and safety of apatinib in patients with advanced colorectal cancer as the late-line treatment.

Medicine (Baltimore) 2018 Dec;97(50):e13635

Department of First Chemotherapy.

There is currently no standard therapeutic regimen available for patients with advanced colorectal cancer in whom the disease continues to progress after 2 or more lines of chemotherapy. The purpose of this study is to investigate the efficacy and safety of apatinib in patients with advanced colorectal cancer for whom at least two lines of prior chemotherapy had failed.Twenty seven patients with advanced colorectal cancer who had failed at least 2 lines chemotherapy were treated with apatinib (500 mg/day). Read More

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http://Insights.ovid.com/crossref?an=00005792-201812140-0009
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http://dx.doi.org/10.1097/MD.0000000000013635DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320137PMC
December 2018
5 Reads
5.723 Impact Factor

Nicotine protects against manganese and iron-induced toxicity in SH-SY5Y cells: Implication for Parkinson's disease.

Neurochem Int 2018 Dec 14;124:19-24. Epub 2018 Dec 14.

Department of Pharmacology, Howard University College of Medicine, Washington, DC, USA. Electronic address:

Manganese (Mn) and iron (Fe) are trace elements that are essential for proper growth and physiological functions as both play critical role in a variety of enzymatic reactions. At high concentrations, however, they can be toxic and cause neurodegenerative disorders, particularly Parkinson-like syndromes. Nicotine, on the other hand, has been shown to have neuroprotective effects against various endogenous or exogenous toxins that selectively damage the dopaminergic cells. Read More

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http://dx.doi.org/10.1016/j.neuint.2018.12.003DOI Listing
December 2018

Just flip it!-CRT implantation in a patient with dextrocardia and situs inversus totalis.

J Arrhythm 2018 Dec 6;34(6):656-658. Epub 2018 Oct 6.

Heart Rhythm Services - St-Paul's Hospital University of British Columbia Vancouver BC Canada.

Implantation of a cardiac resynchronization therapy (CRT) device in patients with congenital heart disease may be challenging because of the particular underlying anatomy. We present the case of a right-sided transvenous implantation of a dual-chamber CRT-D device in a patient with situs inversus totalis and mirror image dextrocardia. To facilitate our anatomic orientation and to overcome unusual hand-eye coordination problems, we decided to flip the fluoroscopic image projection by 180° (right-left), creating the optical impression of a "normalized" heart position (levocardia). Read More

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http://dx.doi.org/10.1002/joa3.12120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288602PMC
December 2018

The Use of Three-Dimensional Printing for Complex Scaphoid Fractures.

J Hand Surg Am 2018 Dec 14. Epub 2018 Dec 14.

Division of Hand and Upper Extremity Surgery, Hospital for Special Surgery, New York, NY. Electronic address:

Scaphoid fractures are one of the most common fractures treated by hand surgeons. The complex anatomy and size of the scaphoid bone can make the reduction and fixation of these fractures technically challenging. Careful preoperative planning is required to ensure stable fixation is achieved. Read More

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http://dx.doi.org/10.1016/j.jhsa.2018.10.018DOI Listing
December 2018

Abnormal dartos fascia in buried penis and hypospadias: Evidence from histopathology.

J Pediatr Urol 2018 Dec 21;14(6):536.e1-536.e7. Epub 2018 Jun 21.

Department of Urology, Dr. Cipto Mangunkusumo National General Hospital, Jakarta Pusat, Indonesia.

Introduction: The importance of the pathology of the dartos fascia in hypospadias and buried penis is still debatable. Understanding the properties of connective tissue of dartos fascia in hypospadias and buried penis may give a clue to the underlying mechanism.

Objective: This study aimed to compare connective tissue and vascularization of dartos fascia between normal penis, buried penis, and hypospadias. Read More

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http://dx.doi.org/10.1016/j.jpurol.2018.04.034DOI Listing
December 2018

Towards viscoelastic characterisation of the human ulnar nerve: An early assessment using embalmed cadavers.

Med Eng Phys 2018 Dec 13. Epub 2018 Dec 13.

Department of Anatomy, College of Medical and Dental Sciences, University of Birmingham, United Kingdom. Electronic address:

Cubital tunnel syndrome is the most prevalent neuropathy of the ulnar nerve and its aetiology is controversial. Potential replacement materials should display similar viscoelastic properties. The purpose of this study was to assess the feasibility and merit of quantifying the frequency-dependent viscoelastic properties of proximal and distal sections of the human ulnar nerve. Read More

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http://dx.doi.org/10.1016/j.medengphy.2018.12.009DOI Listing
December 2018
1.825 Impact Factor

Influence of reduced tip-apex distance on helical blade fixation-a biomechanical study.

J Orthop Res 2018 Dec 13. Epub 2018 Dec 13.

AO Research Institute Davos, Clavadelerstrasse 8, Davos Platz, 7270, Switzerland.

Migration profile of helical blades differs from conventional screw design. Tip-apex distance (TAD) greater than 25 mm is associated with early failure in hip screws. This study investigates the effect of a reduced TAD on helical blade fixation. Read More

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http://dx.doi.org/10.1002/jor.24202DOI Listing
December 2018

Visuospatial Integration and Hand-Tool Interaction in Cognitive Archaeology.

Curr Top Behav Neurosci 2018 Dec 15. Epub 2018 Dec 15.

Sociograph Marketing Science Consulting, Valladolid, Spain.

Testing cognitive hypotheses in extinct species can be challenging, but it can be done through the integration of independent sources of information (e.g., anatomy, archaeology, neurobiology, psychology), and validated with quantitative and experimental approaches. Read More

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http://dx.doi.org/10.1007/7854_2018_71DOI Listing
December 2018

Calretinin Functions in Malignant Mesothelioma Cells Cannot Be Replaced by the Closely Related Ca-Binding Proteins Calbindin-D28k and Parvalbumin.

Int J Mol Sci 2018 Dec 12;19(12). Epub 2018 Dec 12.

Anatomy, Section of Medicine, University of Fribourg, Route Albert-Gockel 1, 1700 Fribourg, Switzerland.

Calretinin (CR; ) belonging to the family of EF-hand Ca-binding proteins (CaBP) is widely used as a positive marker for the identification of human malignant mesothelioma (MM) and functionally was suggested to play a critical role during carcinogenesis of this highly aggressive asbestos-associated neoplasm. Increasing evidence suggests that CR not only acts as a prototypical Ca buffer protein, i.e. Read More

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http://www.mdpi.com/1422-0067/19/12/4015
Publisher Site
http://dx.doi.org/10.3390/ijms19124015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321210PMC
December 2018
3 Reads

An Innovative Technique for Craniocaudal Pedicle Screw Guidance: A Technical Note.

Tech Orthop 2018 Dec 25;33(4):e15-e16. Epub 2017 Dec 25.

Department of Orthopedics, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India.

In spine surgery, pedicle screw instrumentation is being used very commonly. However, putting pedicle screws in the right place and direction needs the use of image intensifier in 2 orthogonal planes. This consumes valuable time while moving the image intensifier and operating table multiple times during the surgery and also excess radiation exposure. Read More

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http://dx.doi.org/10.1097/BTO.0000000000000331DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6250265PMC
December 2018

Corneal Subbasal Nerve Plexus Changes in Severe Diabetic Charcot Foot Deformity: A Pilot Study in Search for a DNOAP Biomarker.

J Diabetes Res 2018 4;2018:5910639. Epub 2018 Nov 4.

Department of Ophthalmology, Rostock University Medical Center, Doberaner Straße 140, 18057 Rostock, Germany.

Introduction: Diabetic neuroosteoarthropathy (DNOAP) early symptoms are unspecific, mimicking general infectious symptoms and rendering a diagnosis challenging. Consequently, unfavourable outcomes occur frequently, with recurrent foot ulceration, infectious complications, and eventually amputation. Corneal confocal microscopy (CCM) of the subbasal nerve plexus (SNP) is used to detect early peripheral neuropathy in diabetic patients without diabetic retinopathy. Read More

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http://dx.doi.org/10.1155/2018/5910639DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247393PMC
November 2018
3 Reads

Sulforaphane-conjugated selenium nanoparticles: towards a synergistic anticancer effect.

Nanotechnology 2019 Feb;30(6):065101

Department of Chemistry, University of Warsaw, Pasteura 1, 02-093, Warsaw, Poland.

Sulforaphane-modified selenium nanoparticles can be prepared in a simple aqueous-phase redox reaction through reduction of selenite with ascorbic acid. The sulforaphane molecules present in the reaction mixture adsorb on the nanoparticle surface, forming an adlayer. The resulting conjugate was examined with several physicochemical techniques, including microscopy, spectroscopy, x-ray diffraction, dynamic light scattering and zeta potential measurements. Read More

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http://stacks.iop.org/0957-4484/30/i=6/a=065101?key=crossref
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http://dx.doi.org/10.1088/1361-6528/aaf150DOI Listing
February 2019
7 Reads

Mechanisms of disease: The endocrinology of obstructive sleep apnoea.

Eur J Endocrinol 2018 Dec 1. Epub 2018 Dec 1.

A Tahrani, University of Birmingham, Institute of Metabolism and Systems Research, Birmingham, United Kingdom of Great Britain and Northern Ireland.

Obstructive sleep apnoea (OSA) is a common disorder that is associated with serious co-morbidities with a negative impact on quality of life, life expectancy and health costs. As OSA is related to obesity and is associated with sleep disruption, increased inflammation and oxidative stress, it is not surprising that OSA has an impact on the secretion of multiple hormones and is implicated in the development of many endocrine conditions. On the other hand, many endocrine conditions that can affect obesity and/or upper airways anatomy and stability have been implicated in the development or worsening of OSA. Read More

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http://dx.doi.org/10.1530/EJE-18-0411DOI Listing
December 2018
1 Read

Distal radial access for coronary angiography and percutaneous coronary intervention: A state-of-the-art review.

Authors:
Thierry Corcos

Catheter Cardiovasc Interv 2018 Dec 11. Epub 2018 Dec 11.

Department of Cardiology, American Hospital of Paris and Hôpital Foch, Suresnes, France.

Since its introduction by Lucien Campeau three decades ago, percutaneous radial artery approach at the forearm has been shown to provide advantages over the femoral approach and has become the standard approach for coronary angiography and intervention. Though infrequent, vascular complications still remain, mainly radial artery occlusion. Therefore, a more distal radial approach at the snuffbox or at the dorsum of hand has been suggested, initially by anethesiologists for perioperative patient monitoring, and more recently by Babunashvili et al. Read More

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http://dx.doi.org/10.1002/ccd.28016DOI Listing
December 2018
2 Reads