Search Our Scientific Publications & Authors

Hand (N Y) 2019 Mar 21:1558944719837694. Epub 2019 Mar 21.

2 INTEGRIS Baptist Medical Center, Oklahoma City, Oklahoma, USA.

Background: There are several congenital hand differences that cause thumb-index (TI) web space deficiency. There is a knowledge gap in the literature about the hand differences that are associated with TI web space deficiency. We aimed to identify these congenital differences and the various specific reconstructive surgical procedures that are used for these conditions. Read More

Hand (N Y) 2019 Mar 21:1558944719836234. Epub 2019 Mar 21.

1 Department of Orthopaedic Surgery and Sports Medicine, Temple University Hospital, Philadelphia, PA, USA.

Background: Hand infections frequently involve the dorsal aspect of the hand and often develop secondary to some traumatic mechanism. Although Staphylococcus aureus is most commonly isolated, anaerobic and polymicrobial infections are not uncommon. To date, treatment is largely anecdotal, with some surgeons preferring a formal debridement in the operating room, while others opt for an initial debridement at the bedside. Read More

Hand (N Y) 2019 Mar 21:1558944719837009. Epub 2019 Mar 21.

2 Holy Cross Hospital, Fort Lauderdale, FL, USA.

Background: Proximal interphalangeal arthroplasty (PIPA) has been indicated for patients suffering from osteoarthritis (OA) or rheumatoid arthritis of the hand. Although there is extensive literature showing the outcomes of PIPA, there is paucity in the literature regarding trends of PIPA in patients with OA of the hand. The purpose of this study was to determine annual primary utilization and revision PIPA trends within the Medicare population with the use of an administrative database. Read More

Sci Rep 2019 Mar 18;9(1):4750. Epub 2019 Mar 18.

Institut Jacques Monod, UMR7592 CNRS-Université Paris Diderot, Sorbonne Paris Cité, F-75205, Paris, France.

Although structural nuclear pore proteins (nucleoporins) are seemingly required in every cell type to assemble a functional nuclear transport machinery, mutations or deregulation of a subset of them have been associated with specific human hereditary diseases. In particular, previous genetic studies of patients with nephrotic syndrome identified mutations in Nup107 that impaired the expression or the localization of its direct partner at nuclear pores, Nup133. In the present study, we characterized the zebrafish nup133 orthologous gene and its expression pattern during larval development. Read More

Periodontol 2000 2019 Feb;79(1):151-167

Unit of Periodontology, Department of Estomatology, Santiago de Compostela University, Santiago de Compostela, Spain.

Recent systematic reviews have shown that the survival rate of immediate implant placement is similar to those with a delayed approach. However, preclinical models and human studies have shown that immediate implant placement per se does not preserve the anatomy of the alveolus, mainly at the buccal bone crest, leading to bony dehiscences and subsequently to soft-tissue recession, with a great impact on esthetic outcomes. On the other hand, preclinical and human studies have identified factors that may prevent bone resorption after immediate implant placement, such as anatomical/biological (alveolus, gingival biotype, periapical/periodontal pathology) and surgical/restorative ones (implant diameter and positioning, flap/flapless, bone and connective tissue grafts, immediate loading/provisionalization, antibiotics). Read More

J Plast Surg Hand Surg 2019 Mar 19:1-6. Epub 2019 Mar 19.

a Department of Plastic and Reconstructive Surgery , Medical/Graduate School of Kagawa University , Takamatsu , Japan.

This study verifies the hypothesis that bone/cartilage proportion in deformed ribs of male pectus excavatum patients varies according to their ages. Anatomical evaluation of the thoraces was performed for 79 male pectus excavatum patients, referring to their three-dimensional computer-tomographic images. The patients were divided into Child Group (5-9 years old: n = 35); Adolescent Group (12-15 years old: n = 15) and Adult Group (18+ years old: n = 29). Read More

Cereb Cortex 2019 Mar 19. Epub 2019 Mar 19.

Institute of Biophysics Carlos Chagas Filho, Federal University of Rio de Janeiro, 21941-902, Rio de Janeiro, Brazil.

The posterior parietal cortex (PPC) is a central hub for the primate forebrain networks that control skilled manual behavior, including tool use. Here, we quantified and compared the sources of thalamic input to electrophysiologically-identified hand/forearm-related regions of several PPC areas, namely areas 5v, AIP, PFG, and PF, of the capuchin monkey (Sapajus sp). We found that these areas receive most of their thalamic connections from the Anterior Pulvinar (PuA), Lateral Posterior (LP) and Medial Pulvinar (PuM) nuclei. Read More

JBJS Essent Surg Tech 2014 Mar 13;3(1):e3. Epub 2013 Feb 13.

Emory Orthopaedic and Spine Center, 59 Executive Park South, Suite 1000, Atlanta, GA 30329. E-mail address for J.W. Xerogeanes: E-mail address for D.C. Todd:

Introduction: Our technique for physeal-sparing, anatomic anterior cruciate ligament (ACL) reconstruction reliably produces femoral tunnels that are of adequate length and that safely avoid the femoral physis without the addition of time-consuming surgical methods or substantial utilization of fluoroscopy.

Step 1 Preoperative Planning: Obtain radiographs and MRI of the knee as well as an anteroposterior radiograph of the hand (to obtain a bone age).

Step 2 Patient Setup Portal Placement And Graft Harvest: The affected knee must be able to flex at least 90° with the end of the operative table lowered, in order to properly visualize the anatomy of the ACL femoral footprint. Read More

Plast Reconstr Surg Glob Open 2018 Nov 5;6(11):e1996. Epub 2018 Nov 5.

Department of Surgery, Division of Plastic and Reconstructive Surgery, Keck School of Medicine of the University of Southern California, Los Angeles, Calif.

Preaxial polydactyly represents an embryologic failure of formation and differentiation that is most commonly classified according to the level of bony duplication. The soft-tissue anatomy and approach to reconstruction of a Wassel VI thumb, an uncommon variant in which complete duplication begins at the metacarpals has not been extensively discussed in the literature. Here, we present 2 patients with a Wassel VI duplication and a shared soft-tissue variant of anomalous insertion of the opponens pollicis muscle onto the radial hypoplastic digit. Read More

Hand (N Y) 2019 Mar 17:1558944719829905. Epub 2019 Mar 17.

1 Massachusetts General Hospital, Division of Plastic and Reconstructive Surgery, Harvard Medical School, Boston, USA.

Background: Firework injuries to the hand can be devastating due to the explosive and ballistic nature of these devices. The aim of this study was to describe the injury and treatment characteristics of patients requiring surgery for firework-related hand injuries and to investigate which factors are associated with an increased utilization of health care resources.

Methods: A retrospective chart review of patients undergoing surgery for firework-related hand injuries at two American College of Surgeons level I trauma centers between 2005 and 2016 was performed. Read More

Arch Oral Biol 2019 Feb 27;101:43-50. Epub 2019 Feb 27.

Division of Oral Anatomy, Department of Oral Biological Science, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan; Department of Craniofacial Development and Stem Cell Biology, Dental Institute, King's College London, Guy's Hospital, London Bridge, London, UK. Electronic address:

Objective: The development of the maxillary bone is under strict molecular control because of its complicated structure. Primary cilia play a critical role in craniofacial development, since defects in primary cilia are known to cause congenital craniofacial dysmorphologies as a wide spectrum of human diseases: the ciliopathies. The primary cilia also are known to regulate bone formation. Read More

World J Plast Surg 2019 Jan;8(1):103-107

Department of Oral- Maxillo-Facial Surgery, Plastic Operations, Dietrich-Bonhoeffer-Klinikum Neubrandenburg, Germany.

Head and neck squamous cell carcinoma (HNSCC) is the most frequent carcinoma of the head and neck region. For coverage of an entire resected mandible with floor of the mouth, 3/4 of the tongue and soft tissue of cheeks and neck bony reconstruction of the mandible and soft tissue reconstruction of tongue, cheeks and a neck large flap are needed. A patient with a superinfected T4 HNSCC was presented to our outpatient clinic. Read More

J Orthop Surg (Hong Kong) 2019 Jan-Apr;27(1):2309499019834072

1 National Key Discipline of Human Anatomy, School of Basic Medical Science, Southern Medical University, Guangdong Province, China.

Objective:: To investigate the effectiveness and accuracy of internal fixation of calcaneal fractures with a three-dimensional (3-D) printing navigation module via the sinus approach.

Methods:: Eleven lateral lower extremity specimens were used in the experiment and divided into the digital design (DD) group ( n = 11) and the real surgery (RS) group ( n = 11). For the DD group, thin-section computed tomography (CT) scans, virtual fracture modeling, virtual bone plate fixation, sinus occlusal module design, and navigation module design were performed for the cadaver specimens. Read More

Bull Hosp Jt Dis (2013) 2019 Mar;77(1):57-63

The basal joint is a collection of articulations at the base of thumb that serve an important function in the overall dexterity of the hand. The unique anatomy of the basal joint provided many evolutionary advantages to the human hand, but also made this joint susceptible to arthrosis and degenerative changes. Surgical treatment of basal joint arthritis has continued to evolve since it was first described in 1949, including excisional arthroplasty, tendon interposition, ligament reconstruction, implant arthroplasty, and arthroscopy. Read More

Int J Comput Assist Radiol Surg 2019 Mar 12. Epub 2019 Mar 12.

Computer Aided Medical Procedures, Johns Hopkins University, Baltimore, MD, USA.

Purpose: As the trend toward minimally invasive and percutaneous interventions continues, the importance of appropriate surgical data visualization becomes more evident. Ineffective interventional data display techniques that yield poor ergonomics that hinder hand-eye coordination, and therefore promote frustration which can compromise on-task performance up to adverse outcome. A very common example of ineffective visualization is monitors attached to the base of mobile C-arm X-ray systems. Read More

Sci Rep 2019 Mar 12;9(1):4200. Epub 2019 Mar 12.

Department of Anatomy and Cell Biology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, QC, Canada.

Mutations in the HNF4A gene cause MODY1 and are associated with an increased risk of Type 2 diabetes mellitus. On the other hand, incretins are hormones that potentiate reductions in blood glucose levels. Given the established role of incretin-based therapy to treat diabetes and metabolic disorders, we investigated a possible regulatory link between intestinal epithelial HNF4α and glucose-dependent insulinotropic polypeptide (GIP), an incretin that is specifically produced by gut enteroendocrine cells. Read More

Br J Neurosurg 2019 Mar 12:1-6. Epub 2019 Mar 12.

a Department of Hand Surgery, Huashan Hospital, Shanghai Medical College , Fudan University , Shanghai , China.

Objective: The objective of the study was to investigate the feasibility of CUBE-SITR MRI and high-frequency ultrasound for the structural imaging of the brachial plexus to exclude neoplastic brachial plexopathy or structural variation and measure the lengths of anterior and posterior divisions of the C7 nerve, providing guidelines for surgeons before contralateral cervical 7 nerve transfer.

Methods: A total of 30 patients with CNS and 20 with brachial plexus injury were enrolled in this retrospective study. All patients underwent brachial plexus CUBE-STIR MRI and high-frequency ultrasound, and the lengths of the anterior and posterior divisions of C7 nerve were measured before surgery. Read More

Contraception 2019 Mar 8. Epub 2019 Mar 8.

Seattle Science Foundation, Seattle, WA.

Objective: Anatomic assessment of the medial upper arm to identify potential sites for insertion of the etonogestrel (ENG) implant.

Study Design: Forty female cadaveric arms were dissected. Two rows of 1 x 2cm dissection windows were created in the inner arm overlying the triceps approximately 2-3 and 4-5cm posterior to the bicipital sulcus (sulcus). Read More

Hand (N Y) 2019 Mar 12:1558944719832040. Epub 2019 Mar 12.

4 Thomas Jefferson University, Philadelphia, PA, USA.

Background: Ultrasound can provide evaluation of the anatomy of the carpal tunnel in a convenient, noninvasive office setting. This study is intended to determine the accuracy and diagnostic performance of ultrasound, used by surgeons, for the evaluation of completeness of carpal tunnel release (CTR).

Methods: Ten cadaver arms underwent randomized sectioning of 0%, 25%, 50%, 75%, or 100% of the transverse carpal ligament. Read More

Front Cell Neurosci 2019 12;13. Epub 2019 Feb 12.

Department of Cellular Biology & Anatomy, Louisiana State University Health Sciences Center-Shreveport, Shreveport, LA, United States.

Chronic ethanol consumption dose-dependently affects both incidence and prognosis of ischemic stroke. Our goal was to determine whether the influence of chronic ethanol consumption on ischemic stroke is related to an altered inflammatory profile in the brain. Male C57BL/6J mice were divided into six groups and gavage fed with 0. Read More

Brain Res 2019 Mar 6. Epub 2019 Mar 6.

Department of Anatomy, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP, Brazil. Electronic address:

Growth hormone (GH) and prolactin (PRL) are known as pleiotropic hormones. Accordingly, the distribution of their receptors comprises several organs and tissues, including the central nervous system. The appropriate secretion of both hormones is essential for sexual maturation and maintenance of reproductive functions, while defects in their secretion affect puberty onset and can cause infertility. Read More

Orthop Clin North Am 2019 Apr;50(2):211-221

Department of Orthopaedic Surgery and Biomedical Engineering, Campbell Clinic, University of Tennessee, 1211 Union Avenue, Suite 510, Memphis, TN 38104, USA.

Distal radial fractures account for up to 18% of all fractures in patients over 65 years of age, and osteoporosis is a predominant factor in these fractures. Fracture treatment may include closed reduction and casting/splinting, external fixation, and open reduction and internal fixation. Read More

Clin Biomech (Bristol, Avon) 2019 Feb 27;63:63-72. Epub 2019 Feb 27.

Shriners Hospitals for Children Northern California, Sacramento, CA, United States; Department of Orthopaedic Surgery, University of California San Francisco, San Francisco, CA, United States. Electronic address:

Background: Clinical assessment of thumb motion is challenging, due to the complex anatomy and motion of the thumb. It is especially difficult to measure hand movement during activity, and to measure the effects of surgery that changes the morphology of the thumb. A three-dimensional model of the hand may enable clinicians to better assess prehension and thumb motion at baseline, and following surgical intervention. Read More

Angle Orthod 2019 Mar 6. Epub 2019 Mar 6.

Objectives:: To assess correlation of dermatoglyphic (DG) pattern with quantitative palatal anatomic parameters measured using three-dimensional (3D) scanning of dental casts and to explore the possibility of utilizing these to predict future occurrence of malocclusion.

Materials And Methods:: Pretreatment casts of 477 Saudi Arabian patients were divided into Class I, II, and III malocclusion groups. Fingerprints were recorded for all hand digits using a digital biometric device. Read More

ANZ J Surg 2019 Mar 5. Epub 2019 Mar 5.

J Anstee Research Group, Department of Plastic, Hand and Faciomaxillary Surgery, Alfred Health, Melbourne, Victoria, Australia.

Background: The anterolateral thigh flap is a workhorse reconstructive flap. Versatility in design is a key strength but perforator anatomy can be variable. Inability to locate perforators prompts consideration of contralateral thigh exploration. Read More

Curr Rev Musculoskelet Med 2019 Mar 5. Epub 2019 Mar 5.

Orthopaedic Surgery, Hand to Shoulder Center, Thomas Jefferson University, 834 Chestnut Street Suite G114, Philadelphia, PA, 19107, USA.

Purpose Of Review: Fragment-specific fixation can be a useful tool in treating distal radius fractures. In order to best utilize these techniques, surgeons require an understanding of the normal anatomy, fracture patterns, approaches, and fixation strategies.

Recent Findings: Fragment-specific fixation may be appropriate for certain fracture patterns particularly when monoblock plating techniques are not sufficient. Read More

J Endod 2019 Mar 1. Epub 2019 Mar 1.

Dental Specialty Center, Brazilian Military Police, Minas Gerais, Brazil.

Introduction: In the literature, several prevalence studies on root canal anatomy using cone-beam computed tomographic technology are currently available although their results remain disperse. This systematic review aimed to appraise and combine, under strict criteria conditions, selected prevalence studies in order to comprehend the distribution of root canal configuration types among different populations.

Methods: This systematic review was registered in PROSPERO. Read More

Med Image Anal 2019 Jan 29;54:45-62. Epub 2019 Jan 29.

Medical Image Processing Group, Department of Radiology, University of Pennsylvania, 602 Goddard building, 3710 Hamilton Walk, 6th Floor, Rm 602W, Philadelphia, PA 19104, United States.

Contouring (segmentation) of Organs at Risk (OARs) in medical images is required for accurate radiation therapy (RT) planning. In current clinical practice, OAR contouring is performed with low levels of automation. Although several approaches have been proposed in the literature for improving automation, it is difficult to gain an understanding of how well these methods would perform in a realistic clinical setting. Read More

Brain Res 2019 Mar 1. Epub 2019 Mar 1.

Department of Clinical Pharmacy, School of Pharmaceutical Sciences, Kobe Gakuin University, 1-1-3 Minatojima, Chuo-ku, Kobe 650-8586, Japan. Electronic address:

N-3 fatty acids, including docosahexaenoic acid (DHA), have a beneficial effect in both pain and psychiatric disorders. In fact, we previously reported that stress-induced pain prolongation might be mediated through the suppression of the G-protein coupled-receptor 40/free fatty acid receptor 1 (GPR40/FFAR1), which is activated by DHA and long-chain fatty acids. However, the involvement of GPR40/FFAR1 ligands in the development of stress-induced chronic pain has not yet been described. Read More

Orthopade 2019 Mar 4. Epub 2019 Mar 4.

Handchirurgie, Vulpiusklinik, Vulpiusstraße 29, 74906, Bad Rappenau, Deutschland.

The thumb has a crucial role in the hand due to its position with regard to the fingers. The CMC-1 joint enables an extraordinary range of motion, since its geometry allows for opposition. The former joint may often succumb to osteoarthritis because a great range of motion in combination with large forces, small contact areas, and thorough usage are always present. Read More

J Clin Orthop Trauma 2019 Mar-Apr;10(2):278-281. Epub 2018 Feb 23.

Dept. of Orthopedics, All India Institute of Medical Sciences, Bhubaneswar, India.

Objectives: Variations of the tendons of the first dorsal compartment of the wrist may be one of reasons of treatment failure and recurrence in De Quervain's tenosynovitis (DQT). The present cadaveric study was designed to look into the variations of the Extensor pollicis brevis (EPB) tendon in Indian population.

Methods: Seventy-seven formaldehyde-fixed cadaveric upper limbs of Indian origins were dissected to observe the number of EPB tendons and its variations. Read More

Urol Oncol 2019 Feb 27. Epub 2019 Feb 27.

Department of Urology, Hokkaido University Graduate School of Medicine, Sapporo, Hokkaido.

Objective: To evaluate the association between the RENAL nephrometry score (RNS) and tumor proliferative activity assessed by immunohistochemistry in patients with localized renal cell carcinoma.

Methods: The current study included 145 pathological T1 (pT1) clear cell renal cell carcinomas (ccRCC). Tumor proliferative activity was assessed with the Ki67 index and microvessel density (MVD). Read More

Cell Death Dis 2019 Mar 1;10(3):211. Epub 2019 Mar 1.

Key Laboratory of the Ministry of Education for Experimental Teratology, Shandong Provincial Key Laboratory of Mental Disorders, Department of Human Anatomy and Histoembryology, School of Basic Medical Sciences, Shandong University, Jinan, Shandong, China.

Offspring of mothers with hyperglycemia during pregnancy have a higher incidence of long-term neuropsychiatric disorders than offspring from a normal pregnancy, indicating that neocortical neurogenesis might be affected by maternal hyperglycemia. A paucity of study evaluating the effects of hyperglycemia on neocortical neurogenetic differentiation of neural stem cells, and the mechanism remains unclear. We sought to investigate the the roles and possible molecular mechanism of maternal hyperglycemia on neocortical neurogenetic differentiation of neural stem cells. Read More

Pediatr Rheumatol Online J 2019 Feb 28;17(1):10. Epub 2019 Feb 28.

Department of Pediatrics, Hacettepe University, Ankara, Turkey.

Background: Nephritis is the most important chronic complication of IgA Vasculitis (IgAV)/Henoch-Schönlein purpura (IGAV/HSP) and thus the main prognostic factor of this most common childhood vasculitis. Since the prognosis and treatment selection depends on the mode of interpretation of biopsy material, in this manuscript we have presented several issues related to the uneven application of different histological classifications in IgAV/Henoch-Schönlein purpura nephritis (HSPN). The nephritis of IgAV/IGAV/HSP will be abbreviated as HSPN for this paper. Read More

Hand (N Y) 2019 Feb 28:1558944719831239. Epub 2019 Feb 28.

1 Western University, London, ON, Canada.

Background: Distal radius fracture reduction by internal fixation is most commonly achieved using volar locking plates (VLPs). Many standard VLP designs make little point contact with radius anatomy, and most postsurgical complications following fixation are attributed to poor implant fit. Sex differences may require consideration in implant design, as females more commonly require VLP removal. Read More

World J Surg Oncol 2019 Feb 27;17(1):44. Epub 2019 Feb 27.

Department of Hand and Plastic Surgery, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, The Second School of Medicine, The Second Clinical Medical College of Wenzhou Medical University, Wenzhou Medical University, No. 109, Xue Yuan Road (West), Lucheng District, Wenzhou, 325000, China.

Background: Bradykinin, a vasoactive peptide, has many biological functions. For example, it accelerates angiogenesis. Thus, we studied the effects of bradykinin on the survival of perforator flaps. Read More

Medicine (Baltimore) 2019 Feb;98(8):e14606

Department of Nuclear Medicine, Third Central Hospital of Tianjin, Tianjin Institute of Hepatobiliary Disease, Tianjin Key Laboratory of Artificial Cell, Artificial Cell Engineering Technology Research Center of Public Health Ministry.

Rationale: Thyroid hemiagenesis is a rare congenital dysplasia, whereas a variety of pathological changes may occur in residual thyroid lobe. The most frequently described pathology in residual thyroid lobe is Graves' hyperthyroidism. Although I therapy has been generally recommended as the preferred treatment for Graves' disease (GD), subjects relating to hemiagenesis are very limited, especially in China. Read More

Clin Orthop Relat Res 2019 Apr;477(4):741-755

I. Gallardo-Calero, A. Sallent, M. Vicente, M. Aguirre, R. Vélez, Orthopedic Surgery Department, Hospital Universitari Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain S. Barrera-Ochoa, F. Soldado, Hand Surgery and Microsurgery Unit, Hospital Sant Joan de Déu, Universitat de Barcelona, Barcelona, Spain S. Barrera-Ochoa, Hand and Microsurgery Unit, Hospital Universitari Quiron-Dexeus, ICATME, Barcelona, Spain M.C. Manzanares, Human Anatomy and Embryology Unit, Dpt Experimental Pathology and Therapeutics, Faculty of Medicine and Health Sciences, University of Barcelona, Barcelona, Spain I. Gallardo-Calero, S. Barrera-Ochoa, A. Sallent, M. Vicente, A. López-Fernández, M. Aguirre, R. Vélez, Vall d'Hebron Research Institute, Musculoskeletal Tissue Engineering Group, Universitat Autònoma de Barcelona, Barcelona, Spain M. De Albert, Radiology Department, Hospital Universitari Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain.

Background: Surgical reconstruction of large bone defects with structural bone allografts can restore bone stock but is associated with complications such as nonunion, fracture, and infection. Vascularized reconstructive techniques may provide an alternative in the repair of critical bone defects; however, no studies specifically addressing the role of vascularized periosteal flaps in stimulating bone allograft revascularization and osseointegration have been reported.

Questions/purposes: (1) Does a vascularized periosteal flap increase the likelihood of union at the allograft-host junction in a critical-size defect femoral model in rats? (2) Does a vascularized periosteal flap promote revascularization of a critical-size defect structural bone allograft in a rat model? (3) What type of ossification occurs in connection with a vascularized periosteal flap?

Methods: Sixty-four rats were assigned to two equal groups. Read More

J Plast Reconstr Aesthet Surg 2019 Feb 10. Epub 2019 Feb 10.

Department of Plastic and Reconstructive Surgery, Plastic Surgery Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, No. 33 Ba-Da-Chu Road, Beijing 100144, PR China. Electronic address:

Background: The medial arm flap has a long history but remains underused despite providing multiple advantages. We reviewed our experience with using the medial arm flap to clarify the distribution of septocutaneous perforators and its relationship with pedicled flap design.

Patients And Methods: This retrospective study included 36 consecutive patients who underwent reconstructive surgery with a medial arm flap (42 arms). Read More

Hand (N Y) 2019 Feb 27:1558944719831238. Epub 2019 Feb 27.

1 Beth Israel Deaconess Medical Center, Boston, MA, USA.

Background: The optimal treatment of human bites to the dorsal metacarpophalangeal region (ie, "fight bite") in the absence of gross purulence is controversial. Few studies have compared the outcomes of operative debridement with expectant wound care and oral antibiotics.

Methods: We performed a retrospective chart review of all patients evaluated at a Level 1 trauma center over a 10-year period. Read More

Radiat Prot Dosimetry 2019 Feb 26. Epub 2019 Feb 26.

Department of Radiation Measurement and Dose Assessment, National Institutes for Quantum and Radiological Sciences and Technology, National Institute of Radiological Sciences, 4-9-1 Anagawa, Inage-ku, Chiba-city, Chiba, Japan.

One of the authors (O.K.) stayed in the area located ~110 km south from the Fukushima Daiichi Nuclear Power Plant during the arrival of radioactive plumes released into the environment due to the accident in March 2011 in Japan. Read More

Plast Surg Nurs 2019 Jan/Mar;39(1):14-17

José María García-Sánchez, MD, is Plastic Surgeon, Department of Plastic and Reconstructive Surgery and Burns, La Fe Hospital, Valencia, Spain. Laura Ibáñez Beltrán, MD, is Pediatrician, Department of Pediatrics, La Fe Hospital, Valencia, Spain. Eduardo Simón-Sanz, MD, is Plastic Surgeon, Department of Plastic and Reconstructive Surgery and Burns, La Fe Hospital, Valencia, Spain. Alberto Ruiz Cases, MD, is Plastic Surgeon, Department of Plastic and Reconstructive Surgery and Burns, La Fe Hospital, Valencia, Spain. Enrique Salmerón-González, MD, is Plastic Surgeon, Department of Plastic and Reconstructive Surgery and Burns, La Fe Hospital, Valencia, Spain. María Dolores Pérez del Caz, MD, is Plastic Surgeon, Department of Plastic and Reconstructive Surgery and Burns, La Fe Hospital, Valencia, Spain.

The upper limb is involved in burns in a high percentage of cases and its reconstruction is extremely important, given the functional impact of this anatomical region. Among the reconstruction choices for severe and large structural defects, the pedicled anterolateral thigh flap is an available option. This case study discusses the utilization of the pedicled anterolateral thigh flap for reconstruction of a complex full-thickness hand burn, when adequate arterial perforators were not available. Read More

Tohoku J Exp Med 2019 02;247(2):139-147

Department of Surgical Oncology, Tohoku University Graduate School of Medicine.

About 20% of patients with breast cancer are likely to develop breast cancer-related lymphedema (BCRL) following an axillary clearance, and BCRL can be refractory or irreversible to treatment. The aim of this pilot randomized controlled study was to evaluate the effectiveness of a 10-min holistic self-care program for patients with BCRL in Japan. The intervention group (n = 22) practiced the BCRL self-care program including 1) modified Japanese Radio Taiso (Rajio Taiso, national calisthenics in Japan), 2) gentle arm exercises combined with deep breathing, 3) central lymphatic drainage, and 4) skin care using a traditional lymphatic drainage technique daily for 6 months, while the control group (n = 21) received usual care from their hospitals. Read More

Glia 2019 Feb 22. Epub 2019 Feb 22.

Department of Ophthalmology, University Hospital of Bern, University of Bern, Bern, Switzerland.

Microglia are the resident tissue macrophages of the central nervous system including the retina. Under pathophysiological conditions, microglia can signal to Müller cells, the major glial component of the retina, affecting their morphological, molecular, and functional responses. Microglia-Müller cell interactions appear to be bidirectional shaping the overall injury response in the retina. Read More

Neoplasma 2019 Feb 17;2019. Epub 2019 Feb 17.

3rd Surgical Clinic, Faculty of Medicine, Comenius University, Bratislava, Slovakia.

In past decades, both prognosis and therapy of rectal cancer patients showed significant improvement, on the other hand, the incidence of rectal carcinoma continues to have a rising tendency. According to current UICC classification, patients in stage II rectal cancer or higher are indicated for neoadjuvant chemoradiotherapy (nCRT). Magnetic resonance imaging (MRI) is currently the most common diagnostic method used for preoperative staging of rectal cancer. Read More

Clin J Sport Med 2019 Feb 13. Epub 2019 Feb 13.

School of Public Health, University of Sydney, Sydney, Australia.

Background: The use of local anesthetic painkilling injections to improve player availability is common practice in elite-level sport.

Objective: To document the published use of local anesthetic injections in sport, according to number of injections, sites of injections, and complications reported.

Data Sources: A systematic search of MEDLINE, Embase, CINAHL, AMED, Cochrane Database of Systematic reviews, SportDiscus, EBSCO Host, and Google Scholar. Read More

J Therm Biol 2019 Feb 9;80:82-88. Epub 2019 Jan 9.

Science Research Department, Alexander Muss High School in Israel (AMHSI) affiliated to the Alexander Muss Institute for Israel Education (AMIIE), Hod HaSharon, Israel. Electronic address:

The continuing development and manufacture of infrared devices, together with improvements in thermal body mapping techniques have simplified surface skin thermography which is being used more extensively than ever before. Normative thermography data, however, remains incomplete. A normative blood redistribution range of skin temperatures was established for use as a reference for laboratory infrared thermography (IT), thermal body mapping, and mass fever screenings. Read More