822 results match your criteria Hairy Leukoplakia


Oral hairy leukoplakia associated with the use of adalimumab.

Cutis 2020 Nov;106(5):E4-E6

Dermatology Center of Southern Indiana, Bloomington, and the Indiana University School of Medicine, Bloomington, USA.

View Article and Full-Text PDF
November 2020

Treatment options for oral hairy leukoplakia: A case report.

Authors:

Dermatol Ther 2020 Sep 27;33(5):e14148. Epub 2020 Aug 27.

View Article and Full-Text PDF
September 2020

Oral Hairy Leukoplakia in Immunocompetent Patients Revisited with Literature Review.

Head Neck Pathol 2021 Jan 11. Epub 2021 Jan 11.

Department of Oral and Maxillofacial Diagnostic Sciences, University of Florida College of Dentistry, 1395 Center Drive, Gainesville, FL, 32610, USA.

Oral hairy leukoplakia (OHL) is an Epstein-Barr virus (EBV) related lesion seen in severely immunocompromised patients especially, those with concomitant human immunodeficiency virus (HIV) infection. It has been rarely reported in immunocompetent patients. OHL most often presents on the lateral border of the tongue as an asymptomatic, white, and corrugated plaque that does not rub off. Read More

View Article and Full-Text PDF
January 2021

Oral Hairy Leukoplakia Related to Orodispersible Budesonide Use.

ACG Case Rep J 2020 Dec 9;7(12):e00502. Epub 2020 Dec 9.

Department of Gastroenterology, Belfast City Hospital, Belfast, Northern Ireland.

View Article and Full-Text PDF
December 2020

Diagnosis of latent tuberculosis infection is associated with reduced HIV viral load and lower risk for opportunistic infections in people living with HIV.

PLoS Biol 2020 12 7;18(12):e3000963. Epub 2020 Dec 7.

Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Zurich, Switzerland.

Approximately 28% of the human population have been exposed to Mycobacterium tuberculosis (MTB), with the overwhelming majority of infected individuals not developing disease (latent TB infection (LTBI)). While it is known that uncontrolled HIV infection is a major risk factor for the development of TB, the effect of underlying LTBI on HIV disease progression is less well characterized, in part because longitudinal data are lacking. We sorted all participants of the Swiss HIV Cohort Study (SHCS) with at least 1 documented MTB test into one of the 3 groups: MTB uninfected, LTBI, or active TB. Read More

View Article and Full-Text PDF
December 2020

Oral health status and treatment needs among HIV/AIDS patients attending antiretroviral therapy center in Western India: A cross-sectional study.

J Family Med Prim Care 2020 Jul 30;9(7):3722-3728. Epub 2020 Jul 30.

Conservative and Endodontics, Daswani Dental College & Research Centre, Kota, Rajasthan, India.

Aims And Objectives: Human immunodeficiency virus infection/acquired immunodeficiency syndrome (HIV/AIDS) is a major public health problem across the globe. Among 37.9 million people are living with HIV in the world and 21. Read More

View Article and Full-Text PDF

A real-world, cross sectional study of oral lesions and their association with CD4 cell counts and HIV viral load in Yunnan, China.

Medicine (Baltimore) 2020 Oct;99(40):e22416

Department of Stomatology, Kunming Medical University Yan An Hospital and Yan An Hospital of Kunming City.

Human immunodeficiency virus (HIV) supresses immune system, primarily cell-mediated immunity. Cluster of differentiation 4 (CD4) cell count, viral load, and oral lesions are the most important laboratory parameters to evaluate the evolution of acquired immunodeficiency syndrome. The present study aims to determine the incidence of HIV-related oral lesions with CD4 cell count and viral load in Yunnan, China. Read More

View Article and Full-Text PDF
October 2020

Oral manifestations of HIV: Can they be an indicator of disease severity? (A systematic review).

Oral Dis 2020 Sep;26 Suppl 1:133-136

Department of Oral Medicine, Faculty of Dentistry, Universitas Indonesia, Jakarta, Indonesia.

Objective: To review the existing research literature on the paradigm that the oral lesions could be an indicator of the disease severity with the objective of documenting the current status of research, highlighting its major findings.

Material And Methods: Publications were identified through a careful search, of which a majority focused on oral lesions as an indicator for HIV progression. A PubMed journal search of 10 years OF period publication (2009-2019) for "oral lesion, oral manifestation, indicator, HIV and HIV-associated" was performed and analysed. Read More

View Article and Full-Text PDF
September 2020

The global changing pattern of the oral manifestations of HIV.

Authors:
Anwar R Tappuni

Oral Dis 2020 Sep;26 Suppl 1:22-27

Institute of Dentistry, Queen Mary University of London, London, UK.

The significance of the oral manifestations of HIV has been widely recognised since the start of the epidemic. It is estimated that more than 38 million people are living with HIV currently, with more than a third presenting with oral manifestations. Access to optimum clinical management and effective treatment in resource-rich countries has led to a remarkable decrease in some of the oral manifestations in the HIV population but this is not mirrored in developing countries, where most HIV-positive patients reside. Read More

View Article and Full-Text PDF
September 2020

Detection of Epstein-Barr virus DNA in saliva of HIV-1-infected individuals with oral hairy leukoplakia.

Oral Dis 2020 Sep;26 Suppl 1:158-160

Oral Medicine Department, Faculty of Dentistry, Universitas Padjadjaran, Sumedang, Indonesia.

We present three cases of oral hairy leukoplakia (OHL) in whom the diagnosis was established by EBV DNA detection in whole saliva. Three HIV-infected patients came to the Oral Medicine Clinic with similar chief complaints of asymptomatic white lesions on the tongue. All patients were diagnosed with suspected OHL and oral thrush also in the first patient. Read More

View Article and Full-Text PDF
September 2020

A 45-year-old Female with an Atypical Presentation of Pharyngitis.

Clin Pract Cases Emerg Med 2020 May 27;4(2):234-240. Epub 2020 Apr 27.

Reynold's Memorial Hospital, Department of Emergency Medicine, Glen Dale, West Virginia.

Introduction: Emergency physicians are trained to treat a variety of ailments in the emergency department (ED), some of which are emergent, while others are not. A common complaint seen in the ED is a sore throat. While most sore throats are easily diagnosed and treated, less common causes are often not considered in the differential diagnoses. Read More

View Article and Full-Text PDF

Oral hairy leukoplakia in a child using a corticosteroid nasal spray.

Pediatr Dermatol 2020 Jul 5;37(4):721-723. Epub 2020 May 5.

Department of Biosciences and Oral Diagnosis, Institute of Science and Technology, São Paulo State University (Unesp), São José dos Campos, Brazil.

We report a case of atypical oral hairy leukoplakia (OHL) in a 9-year-old immunocompetent girl treated with fluticasone propionate nasal spray for allergic rhinitis. The OHL in childhood is uncommon and should be included in a differential diagnosis of white lesions in the oral mucosa. Read More

View Article and Full-Text PDF

Treatment options for oral hairy leucoplakia: A case report.

Dermatol Ther 2020 05 3;33(3):e13425. Epub 2020 May 3.

Department of Dermatology, University Hospital Basel, Basel, Switzerland.

View Article and Full-Text PDF

Oral Manifestations in HIV-TB Co- infected Patients and Their Correlation with CD4 Count in Telangana State, India.

J Int Soc Prev Community Dent 2020 Jan-Feb;10(1):21-35. Epub 2020 Jan 24.

Department of Oral and Maxillofacial Pathology, Panineeya Mahavidyalaya Institute of Dental Sciences, Dilsukhnagar, Hyderabad, Telangana, India.

Aims And Objectives: Human immunodeficiency virus (HIV)-related oral lesions are often an early finding, and they reflect the underlying immunosuppression, and tuberculosis (TB) coinfection can have further deteriorating effect. Hence, a cross-sectional study was conducted to evaluate clinical and oral presentations of patients coinfected with HIV-TB, correlating with various parameters such as the type of TB with CD4 cell count, the type of TB with oral manifestations, site of the lesion, oral manifestations with CD4 cell counts, age, and gender.

Materials And Methods: A cross-sectional study was conducted among selected 200 patients coinfected with HIV-TB, registered at Gandhi Medical College, Hyderabad, Telangana, India, and demographic data, CD4 count, diagnosis of TB, and clinical presentation of TB were correlated with site, age, gender, and the type of lesions in the oral cavity. Read More

View Article and Full-Text PDF
January 2020

Oral leukoplakia; a proposal for simplification and consistency of the clinical classification and terminology.

Authors:
I van der Waal

Med Oral Patol Oral Cir Bucal 2019 Nov 1;24(6):e799-e803. Epub 2019 Nov 1.

Department of Oral and Maxillofacial Surgery and Oral Pathology VU University Medical Center P.O. Box 7057, 1007 MB Amsterdam, The Netherlands

There is a distinct lack of uniformity in the definitions and clinical terminologies related to oral leukoplakia and leukoplakialike lesions and disorders. Proposals have been put forward to subclassify leukoplakia into a homogeneous and a non-homogeneous type based on color only, being either predominantly white or mixed whiteand-red, respectively, irrespective of the texture of the lesion. In this proposal there is no need anymore to regard the poorly defined proliferative verrucous leukoplakia as a separate entity. Read More

View Article and Full-Text PDF
November 2019

Racial differences in dermatologic conditions associated with HIV: A cross-sectional study of 4679 patients in an urban tertiary care center.

J Am Acad Dermatol 2020 May 6;82(5):1117-1123. Epub 2019 Sep 6.

Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, Maryland; Hopkins Bloomberg School of Public Health, Baltimore, Maryland. Electronic address:

Background: Because of reduced mortality, patients with HIV are living longer and presenting with chronic diseases. Little is known about racial differences in dermatologic conditions associated with HIV infection.

Objective: This study examines associated dermatologic conditions in a large population of patients with HIV at a tertiary care center with a diverse patient population. Read More

View Article and Full-Text PDF

Oral Hairy Leukoplakia in Patients With No Evidence of Immunosuppression: A Case Series and Review of the Literature.

J Can Dent Assoc 2018 05;84:i4

Objectives: Oral hairy leukoplakia (OHL) is caused by Epstein-Barr virus (EBV) and is often associated with HIV and other immunosuppressive conditions. It is rare in HIV-negative patients, but has been reported in patients who use immune-modulating medications (e.g. Read More

View Article and Full-Text PDF

HIV status does not worsen oral health outcomes.

J Clin Periodontol 2019 06;46(6):640-641

Department of Oral Biology, School of Dental Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.

Last January 31st, Journal of Clinical Periodontology just made available the report titled "A Retrospective Analysis of Dental Implant Survival in HIV Patients," which concluded that "implants placed in HIV-positive patients had similar survival rates as HIV-negative patients." These data support our hypothesis that infection by HIV does not lead to worse oral health outcomes, including worse periodontitis. We looked 6,092 individuals and selected all HIV-positive subjects (N = 73) and matched them by age, sex, ethnicity, and smoking habits with 261 HIV-negative control subjects. Read More

View Article and Full-Text PDF

Hairy Tongue: Differential Diagnosis by Use of Widefield Optical Fluorescence.

Braz Dent J 2019 Mar-Apr;30(2):191-196. Epub 2019 Apr 4.

Núcleo de Pesquisa em Química Biológica (NQBio), UFSJ - Universidade Federal de São João Del Rei, Divinópolis, MG, Brasil.

Hairy tongue is a benign pathology, characterized clinically by hyperkeratinized plaques on the dorsal surface of the tongue, hairlike, whose coloration ranges from unpigment, whitish, yellowish, green, brown to black. Diagnosis is clinical, and, in cases of whitish plaques, it may be difficult to differentiate between oral hairy leukoplakia, potentially malignant leukoplakia or squamous cell carcinoma. Thus, widefield optical fluorescence complementary examination may allow a better visualization of the local hairlike pattern of hyperkeratinization, typical of the hairy tongue, facilitating the diagnosis. Read More

View Article and Full-Text PDF
October 2019

Knowledge of Oral Cancer among the Fourth and Fifth Year Dental Students.

Acta Stomatol Croat 2018 Dec;52(4):340-347

Department of Oral Medicine, School of Dental Medicine, University of Zagreb, Zagreb, Croatia.

Background: The literature data show insufficient knowledge and awareness about oral cancer among dental and medical students.

Objective: To assess the knowledge of graduating dental students regarding oral cancer and to assess their awareness regarding the prevention and early detection of oral cancer. Also student's smoking status was examined aimed to investigate their attitude towards smoking as a risk factor for development of oral cancer and to assess the prevalence of smoking among dental students. Read More

View Article and Full-Text PDF
December 2018

A White Patch on the Tongue.

JAMA Dermatol 2018 12;154(12):1475-1476

Section of Oral and Maxillofacial Pathology, Division of Dermatopathology, Department of Dermatology, University of Pennsylvania Health System, Philadelphia.

View Article and Full-Text PDF
December 2018

Oral hairy leukoplakia in healthy immunocompetent patients: a small case series.

Oral Maxillofac Surg 2018 Sep 6;22(3):335-339. Epub 2018 Aug 6.

Department of Oral Medicine, The University of Bristol Dental Hospital, Lower Maudlin Street, Bristol, BS1 2LY, England.

Background: Oral hairy leukoplakia (OHL) is caused by the Epstein-Barr virus (EBV) and usually presents in patients with human immunodeficiency virus (HIV) infection and systemic immunosuppression. It is rarely seen in patients who are immunocompetent. It is clinically characterised as an asymptomatic, soft, white and corrugated lesion that cannot be scraped from the surface it adheres to. Read More

View Article and Full-Text PDF
September 2018

Systematic review of the changing pattern of the oral manifestations of HIV.

J Investig Clin Dent 2018 Nov 17;9(4):e12351. Epub 2018 Jul 17.

Department of Oral Medicine, Institute of Dentistry, Queen Mary University of London, London, UK.

The purpose of the present study paper was to review the reported prevalence of the oral manifestations of HIV (OM-HIV) worldwide since 1980, and to determine the global variation in its prevalence over time. PubMed, Scopus, Embase and Google Scholar were searched. The filter "English" was used. Read More

View Article and Full-Text PDF
November 2018

Encyclopedia of EBV-Encoded Lytic Genes: An Update.

Authors:
Takayuki Murata

Adv Exp Med Biol 2018 ;1045:395-412

Department of Virology, Nagoya University Graduate School of Medicine, Nagoya, Japan.

In addition to latent genes, lytic genes of EBV must also be of extreme significance since propagation of the virus can be achieved only through execution of lytic cycle. Research on EBV lytic genes may thus prevent spreading of the virus and alleviate disorders, such as infectious mononucleosis and oral hairy leukoplakia, which are highly associated with EBV lytic infection. Moreover, recent advancements have been demonstrating that at least several lytic genes are expressed to some extent even during latent state. Read More

View Article and Full-Text PDF
November 2018

Prevalence and Distribution of Oral Mucosal Lesions by Sex and Age Categories: A Retrospective Study of Patients Attending Lebanese School of Dentistry.

Int J Dent 2018 17;2018:4030134. Epub 2018 May 17.

Faculty of Pharmacy, Lebanese University, Beirut, Lebanon.

Background: Prevalence and distribution of oral mucosal lesions in a sample of Lebanese population attending the School of Dentistry of Lebanese University is necessary to evaluate their oral health situation.

Objectives: The aim of the present study was to determine the prevalence and distribution of oral mucosal lesions of patients attending the School of Dentistry.

Methods: A descriptive study was carried out by retrospectively examining a total of 231 medical and clinical examination record files of patients, attending the School of Dentistry Lebanese University for multidisciplinary dental treatments. Read More

View Article and Full-Text PDF

Oral lesions as an important marker for HIV progression.

Dermatol Online J 2017 Sep 15;23(9). Epub 2017 Sep 15.

Laboratory of Virology, Institute of Tropical Medicine of São Paulo, University of São Paulo, São Paulo, Brazil 2 Department of Stomatology, Division of General Pathology, School of Dentistry, University of São Paulo, São Paulo, Brazil. br.

Background: Oral hairy leukoplakia (OHL) is a benign lesion caused by Epstein-Barr virus (EBV) replication in the oral epithelium affecting the borders of the tongue. It is strongly associated with immunosuppression, especially in HIV+ adults but is uncommon in pediatric population. The aim of the study is to show the importance of the correct diagnosis of OHL and its influence on HIV treatment. Read More

View Article and Full-Text PDF
September 2017

Prevalence of HIV-related oral manifestations and their association with HAART and CD4+ T cell count: a review.

J Biol Regul Homeost Agents 2018 Jan-Feb;32(2 Suppl. 1):51-59

Department of Medicine and Surgery, University of Insubria, Varese, Italy.

HIV infection is one of the major health problem of the last decades. This disease causes a chronic infection that can lead to acquired immunodeficiency syndrome (AIDS). According to the Global AIDS update, released in 2016 by HIV department of World Health Organization (WHO) and by the Joint United Nations Program on HIV/AIDS (UNAIDS), at the end of 2015, 36. Read More

View Article and Full-Text PDF
February 2019

Oral lesions associated with human immunodeficiency virus in 75 adult patients: a clinical study.

J Korean Assoc Oral Maxillofac Surg 2017 Dec 26;43(6):388-394. Epub 2017 Dec 26.

Department of Oral Medicine and Diagnosis, School of Dentistry, Lebanese University, Beirut, Lebanon.

Objectives: The objective of this study was to investigate the presence of oral lesions in human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) patients in a descriptive cross-sectional study, and to establish their presence according to levels of CD4+ cells (including the CD4+/CD8+ cell ratio).

Materials And Methods: A total of 75 patients infected with HIV were included. Oral lesions were observed and classified using World Health Organization classification guidelines. Read More

View Article and Full-Text PDF
December 2017

Considerations in the diagnosis of oral hairy leukoplakia-an institutional experience.

Oral Surg Oral Med Oral Pathol Oral Radiol 2018 03 15;125(3):232-235. Epub 2017 Nov 15.

Department of Diagnostic Sciences, School of Dentistry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

Objective: We report here the 10-year experience with oral hairy leukoplakia (OHL) at the Division of Oral and Maxillofacial Pathology at the University of North Carolina at Chapel Hill, NC, USA.

Study Design: All the associated hematoxylin and eosin and Epstein-Barr virus encoding region in situ hybridization slides of OHL cases between January 1, 2008, and February 1, 2017, were retrieved and reviewed. Collected demographic characteristics, clinical presentation, medical and social histories were reviewed and reported. Read More

View Article and Full-Text PDF