83,990 results match your criteria Hair Transplantation


Occupational exposure to metals and other elements in the tractor production.

PLoS One 2018 14;13(12):e0208932. Epub 2018 Dec 14.

National Center of Occupational Safety and Health, Minsk, Belarus.

Background: Exposure to metals via air sampling in workplace has been extensively studied; however, the magnitude of individual exposure in various occupational groups may vary dramatically. The aim of this cross-sectional study was to ascertain exposure to selected metals from metal fumes in a series of typical workplaces of contemporary tractor production.

Methods: Ninety-eight (median age 41 (interquartile range (IQR) 23) years, all men) workers from Minsk Tractor Plant were categorized into four groups, including assembly shop workers (group 1); thermal shop staff (group 2); steelmakers (group 3) and welders (group 4). Read More

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December 2018

[Research progress on auditory neuropathy spectrum disorder and cochlear implantation in infants and young children].

Authors:
J Y Chen Y X Li

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Jul;32(14):1120-1124

Auditory neuropathy is a disorder characterized by absent or severely abnormal auditory brainstem response (ABR) with intact outer hair cell function, as evidenced by the presence of evoked otoacoustic emissions and/or cochlear microphonics. Unlike patients with sensory hearing loss who show clinical evidence of impaired outer hair cell function. For ANSD patients, clinical rehabilitation is mainly limited to hearing aid wearing and cochlear implantation. Read More

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A homozygous MITF mutation leads to familial Waardenburg syndrome type 4.

Am J Med Genet A 2018 Dec 14. Epub 2018 Dec 14.

Department of Otolaryngology - Head and Neck Surgery, The Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.

Waardenburg syndrome (WS) is a genetic disorder characterized by hearing loss and pigmentary abnormalities with variable penetrance. Though heterozygous mutations in MITF are a major cause for Waardenburg syndrome type 2 (WS2), homozygous mutations in this gene and the associated phenotype have been rarely characterized. In this study, we identified a novel p. Read More

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December 2018
1 Read

A highly resistant structure between the cuticle and the cortex of human hair. II. - CARB, a penetration barrier.

Authors:
Toshie Takahashi

Int J Cosmet Sci 2018 Dec 14. Epub 2018 Dec 14.

Development Research, Kao Corporation, 2-1-3, Bunka, Sumida-ku, Tokyo, 131-8501, Japan.

Objective: We previously reported that a chemically resistant structure is present at the interface between the cuticle and the cortex of human hair. The goal of this study was to identify the position of that structure and to clarify its barrier ability.

Methods: Untreated, partially and completely decuticled hair fibers were characterized. Read More

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December 2018

Effects of Extrusion Conditions on Chemical Properties of Extruded White Ginseng Root Hair.

J Sci Food Agric 2018 Dec 12. Epub 2018 Dec 12.

Department of Food Science and Engineering, Yanbian University, Yanbian, China.

Background: This study was to investigate the significant effects of extrusion process variables on chemical properties of extruded white ginseng root hair. The extrusion conditions were set as follows: barrel temperature (110 and 140°C), moisture content (20 and 30%), and screw speed (200 and 300 rpm). The powder of white ginseng root hair was extruded as L (2 ) orthogonal experimental design. Read More

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December 2018

Canine non-epitheliotropic CD4-positive cutaneous T-cell lymphoma: a case report.

Vet Med Sci 2018 Dec 12. Epub 2018 Dec 12.

Synergy Animal General Hospital, Kawaguchi, Saitama, Japan.

A 5-year-old, spayed female French Bulldog presented with multiple papules on the skin of the scapular area. Histopathological examination of punch biopsy samples revealed dense infiltration of small lymphoid cells in the superficial dermis and in areas surrounding hair follicles. Immunohistochemical analysis indicated that these cells were positive for CD3, CD4, and TCRαβ, but negative for CD1c, CD8α, CD8β, CD11c, CD20, CD45RA, CD90, MHC-II, and TCRγδ. Read More

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December 2018
2 Reads

Allergic contact connubial dermatitis caused by hair products.

Contact Dermatitis 2018 Dec 12. Epub 2018 Dec 12.

Immunology and Allergology Department, Centro Hospitalar Vila Nova de Gaia/Espinho, Espinho, Portugal.

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December 2018

Allogrooming behavior inCercocebus torquatus: The case for the hygienic functional hypothesis.

Primates 2000 Apr;41(2):199-207

Departamento de Psiquiatría y Psicobiología Clínica, Universidad de Barcelona, Passeig de la Vall d'Hebron 171, 08035, Barcelona, Spain.

The hygienic functional hypothesis of allogrooming behavior was examined in two captive groups (N=9 andN=8) of white-crowned mangabeys (Cercocebus torquatus lunulatus) by analyzing: (1) the corporal distribution of manipulation type according to hair density, and (2) the corporal distribution of allogrooming according to presence of wounds. In both groups the sites with higher hair density received more bouts of Superficial Grooming, which implies a tactile screening of a fragment of the body surface. Only one group tended to emit more allogrooming on the body sites when they were wounded. Read More

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Analysis of Artisanal Small-scale Gold Mining Sector in West Sumbawa Regency, Indonesia.

J Health Pollut 2016 Dec 19;6(12):26-33. Epub 2016 Dec 19.

Agriculture Faculty, University of Mataram, Indonesia.

Background: The high value of gold reserves in West Sumbawa Regency (WSR) and West Nusa Tenggara Province, Indonesia has resulted in an increase in small-scale gold mining activity in this area. Artisanal and small-scale gold mining (ASGM) is an attractive alternative livelihood for rural workers because it has good potential to improve the wealth of a community. Miners need very little training to mine gold and the transition from traditional farming or fishing is easy to make. Read More

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December 2016

Effect of Mercury Exposure on Renal Function and Hematological Parameters among Artisanal and Small-scale Gold Miners at Sekotong, West Lombok, Indonesia.

J Health Pollut 2015 Dec 21;5(9):25-32. Epub 2015 Dec 21.

Agriculture Faculty, University of Mataram, Mataram, Indonesia.

Background: Mercury is a toxic metal with effects on human health ranging from acute to chronic in a very short time of exposure. Artisanal and small-scale gold mining (ASGM) is the main source of direct human exposure to mercury. Human exposure to mercury (Hg) can occur through both direct inhalation of mercury vapor and consumption of material taken from contaminated areas. Read More

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December 2015

The Role of Vitamins and Minerals in Hair Loss: A Review.

Dermatol Ther (Heidelb) 2018 Dec 13. Epub 2018 Dec 13.

Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, 1475 NW 12th Ave. Suite 2175, Miami, FL, 33136, USA.

People commonly inquire about vitamin and mineral supplementation and diet as a means to prevent or manage dermatological diseases and, in particular, hair loss. Answering these queries is frequently challenging, given the enormous and conflicting evidence that exists on this subject. There are several reasons to suspect a role for micronutrients in non-scarring alopecia. Read More

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December 2018
2 Reads

Waardenburg Syndrome and Left Persistent Superior Vena Cava.

J Clin Imaging Sci 2018 15;8:44. Epub 2018 Nov 15.

Department of Radiology, University of Kentucky, Kentucky, USA.

Waardenburg syndrome (WS) is a rare genetic disorder secondary to neural crest cell developmental abnormalities. It is predominantly described as an auditory-pigmentary syndrome with diverse patient presentation, typically involving congenital sensorineural hearing loss and pigmentation abnormalities of the skin, hair, and iris. Other developmental abnormalities that may be associated with this syndrome are Hirschsprung's disease and a myriad of cardiovascular congenital defects. Read More

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November 2018
1 Read

Phospholipase A in skin biology: new insights from gene-manipulated mice and lipidomics.

Inflamm Regen 2018 7;38:31. Epub 2018 Dec 7.

1Laboratory of Microenvironmental and Metabolic Health Science, Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655 Japan.

The skin represents one of the tissues that are most profoundly influenced by alterations in the quality of lipids (lipoquality). Lipids not only constitute cellular membranes, but also serve as bioactive lipid mediators and essential components of the skin barrier. Phospholipase A (PLA) enzymes supply fatty acids and lysophospholipids from membrane phospholipids, thereby variably affecting cutaneous homeostasis. Read More

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December 2018
1 Read

Bone marrow-derived epithelial cells and hair follicle stem cells contribute to development of chronic cutaneous neoplasms.

Nat Commun 2018 Dec 13;9(1):5293. Epub 2018 Dec 13.

Department of Pathology and Cell Biology, Columbia University, New York, 10032, NY, USA.

We used allogeneic bone marrow transplantation (BMT) and a mouse multistage cutaneous carcinogenesis model to probe recruitment of bone marrow-derived epithelial cells (BMDECs) in skin tumors initiated with the carcinogen, dimethylbenz[a]anthracene (DMBA), and promoted with 12-O-tetradecanolyphorbol-13-acetate (TPA). BMDECs clustered in the lesional epithelium, expressed cytokeratins, proliferated, and stratified. We detected cytokeratin induction in plastic-adherent bone marrow cells (BMCs) cultured in the presence of filter-separated keratinocytes (KCs) and bone morphogenetic protein 5 (BMP5). Read More

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December 2018

Plasma-induced unconventional shock waves on oil surfaces.

Sci Rep 2018 Dec 13;8(1):17813. Epub 2018 Dec 13.

Institute of Technological Sciences, Wuhan University, Wuhan, Hubei, 430072, China.

Electric corona discharge in a multi-phase system results in complex electro-hydrodynamic phenomena. We observed unconventional shock wave propagation on an oil thin film sprayed over a polymer-coated conductor. A hair-thin single shock wave arose when the high voltage bias of an overhung steel needle was abruptly removed. Read More

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December 2018

Tissue engineering of human hair follicles using a biomimetic developmental approach.

Nat Commun 2018 Dec 13;9(1):5301. Epub 2018 Dec 13.

Department of Dermatology, Columbia University Medical Center, New York, NY, 10032, USA.

Human skin constructs (HSCs) have the potential to provide an effective therapy for patients with significant skin injuries and to enable human-relevant drug screening for skin diseases; however, the incorporation of engineered skin appendages, such as hair follicles (HFs), into HSCs remains a major challenge. Here, we demonstrate a biomimetic approach for generation of human HFs within HSCs by recapitulating the physiological 3D organization of cells in the HF microenvironment using 3D-printed molds. Overexpression of Lef-1 in dermal papilla cells (DPC) restores the intact DPC transcriptional signature and significantly enhances the efficiency of HF differentiation in HSCs. Read More

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December 2018
1 Read

RSL Class Ⅱ Transcription Factors Guide the Nuclear Localization of RHL1 to Regulate Root Hair Development.

Plant Physiol 2018 Dec 13. Epub 2018 Dec 13.

Kyung Hee University CITY: Yongin STATE: Gyeonggi-do POSTAL_CODE: 17104 Korea (South), Republic Of

Root hairs are important for absorption of nutrients and water from the rhizosphere. The ROOT HAIR DEFECTIVE-SIX LIKE (RSL) Class Ⅱ family of transcription factors is expressed preferentially in root hairs and has a conserved role in root hair development in land plants. We functionally characterized the seven members of the RSL Class II subfamily in the rice (Oryza sativa) genome. Read More

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December 2018

Mosaicism in carrier of Duchenne muscular dystrophy mutation - Implication for prenatal diagnosis.

Taiwan J Obstet Gynecol 2018 Dec;57(6):878-880

Center for Gene-Protein Research, Hanoi Medical University, Hanoi, Vietnam. Electronic address:

Objective: Duchenne muscular dystrophy (DMD) is a severe disorder caused by mutation in the X-linked dystrophin gene, therefor carrier testing is required for all female family members. However, there are cases mutation analysis cannot detect any mutation due to a phenomenon called mosaicism. The case report describes a case of mosaicism in a DMD carrier and discusses the approach in diagnosis and counseling of familial disorder. Read More

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December 2018

A Comparison of Stress Perception in International and Local First Semester Medical Students Using Psychometric, Psychophysiological, and Humoral Methods.

Int J Environ Res Public Health 2018 Dec 11;15(12). Epub 2018 Dec 11.

Department of General Internal Medicine and Psychosomatics, University Hospital Heidelberg, Ruprecht-Karls-University Heidelberg, 69115 Heidelberg, Germany.

(1) Medical doctors and medical students show increased psychological stress levels. International medical students seem to be particularly vulnerable. (2) We compared different methods of assessing stress levels in international and local first year medical students. Read More

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December 2018

Evaluation of Serum Paraoxonase, Arylesterase, Prolidase Activities and Oxidative Stress in Patients with Alopecia Areata.

Skin Pharmacol Physiol 2018 Dec 13;32(2):59-64. Epub 2018 Dec 13.

Private practice, Kutahya, Turkey.

Background: Alopecia areata (AA) is a disease characterized by the hair loss sharply limited in any part of the body, especially on the scalp, in circular or oval areas. The purpose of this study is to search the serum paraoxonase 1 (PON1), arylesterase and oxidative status with serum prolidase activities in people with AA.

Methods: The study included 60 AA and 50 healthy control subjects. Read More

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December 2018

Genome-wide meta-analysis implicates mediators of hair follicle development and morphogenesis in risk for severe acne.

Nat Commun 2018 Dec 12;9(1):5075. Epub 2018 Dec 12.

Department of Medical and Molecular Genetics, School of Basic & Medical Biosciences, King's College London, London, SE1 9RT, UK.

Acne vulgaris is a highly heritable common, chronic inflammatory disease of the skin for which five genetic risk loci have so far been identified. Here, we perform a genome-wide association study of 3823 cases and 16,144 controls followed by meta-analysis with summary statistics from a previous study, with a total sample size of 26,722. We identify 20 independent association signals at 15 risk loci, 12 of which have not been previously implicated in the disease. Read More

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December 2018

Non-ossifying fibroma with a pathologic fracture in a 12-year-old girl with tricho-rhino-phalangeal syndrome: a case report.

BMC Med Genet 2018 Dec 12;19(1):211. Epub 2018 Dec 12.

Department of Endocrinology and Diabetes, The First Affiliated Hospital of Xiamen University, 55# Zhenhai Road, Xiamen, 361003, China.

Background: Tricho-rhino-phalangeal syndrome (TRPS) is a rare autosomal dominant genetic disorder characterized by distinctive craniofacial and skeletal abnormalities, while non-ossifying fibroma (NOF) is a common benign bone tumour in children and adolescents. To date, no case of TRPS coexisting with NOF has been reported. This report presents a 12-year-old girl who had the characteristic features of tricho-rhino-phalangeal syndrome and non-ossifying fibroma with a fibula fracture. Read More

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December 2018

Scalable biosynthesis of melanin by the basidiomycete Armillaria cepistipes.

J Agric Food Chem 2018 Dec 12. Epub 2018 Dec 12.

Natural melanin features many interesting properties, including the ability to shield electromagnetic radiation, to act as scavenger for radical and reactive oxygen species and the capacity to chelate different metal ions. For these reasons, melanin is becoming increasingly relevant for the development of functional materials, for potential applications such as cosmetics, drug delivery and water purification. However, the extraction and purification of melanin from conventional sources (e. Read More

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December 2018

Implementation of human biomonitoring in the Dehcho region of the Northwest Territories, Canada (2016-2017).

Arch Public Health 2018 3;76:73. Epub 2018 Dec 3.

1School of Public Health and Health Systems, Faculty of Applied Health Sciences, University of Waterloo, 200 University Ave W, Waterloo, ON Canada.

Background: Human biomonitoring represents an important tool for health risk assessment, supporting the characterization of contaminant exposure and nutrient status. In communities where country foods (locally harvested foods: land animals, fish, birds, plants) are integrated in the daily diet, as is the case in remote northern regions where food security is a challenge, such foods can potentially be a significant route of contaminant exposure. To assess this issue, a biomonitoring project was implemented among Dene/Métis communities of the Dehcho region of the Northwest Territories, Canada. Read More

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December 2018

Spiking Pattern of the Mouse Developing Inner Hair Cells Is Mostly Invariant Along the Tonotopic Axis.

Front Cell Neurosci 2018 14;12:407. Epub 2018 Nov 14.

Institut des Neurosciences de Montpellier (INM), Inserm, University of Montpellier, Montpellier, France.

During development, the sensory cells of the cochlea, the inner hair cells (IHCs), fire spontaneous calcium action potentials. This activity at the pre-hearing stage allows the IHCs to autonomously excite the auditory nerve fibers and hence, represents an efficient mechanism to shape the tonotopic organization along the ascending auditory pathway. Using calcium imaging, we show that the activity in the developing cochlea consists of calcium waves that propagate across the supporting and sensory cells. Read More

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November 2018

The impact of external facial features on the construction of facial composites.

Ergonomics 2018 Dec 7:1-54. Epub 2018 Dec 7.

d School of Psychology , University of Central Lancashire , Preston PR1 2HE.

Witnesses may construct a composite face of a perpetrator using a computerised interface. Police practitioners guide witnesses through this unusual process, the goal being to produce an identifiable image. However, any changes a perpetrator makes to their external facial-features may interfere with this process. Read More

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December 2018

A novel and safe small molecule enhances hair follicle regeneration by facilitating metabolic reprogramming.

Exp Mol Med 2018 Dec 6;50(12):160. Epub 2018 Dec 6.

Department of Functional Genomics, Korea University of Science & Technology (UST), 217 Gajungro, Yuseong-gu, Daejeon, 34113, Republic of Korea.

Targeting hair follicle regeneration has been investigated for the treatment of hair loss, and fundamental studies investigating stem cells and their niche have been described. However, knowledge of stem cell metabolism and the specific regulation of bioenergetics during the hair regeneration process is currently insufficient. Here, we report the hair regrowth-promoting effect of a newly synthesized novel small molecule, IM176OUT05 (IM), which activates stem cell metabolism. Read More

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December 2018

Trichorhinophalangeal syndrome.

Reumatol Clin 2018 Dec 3. Epub 2018 Dec 3.

Servicio de Inmunología, Hospital Clinic, Barcelona, España.

Trichorhinophalangeal syndrome I (TPRSI) has an autosomal dominant inheritance; the proportion of «de novo» cases is unknown. It is characterized by unique facial features, bulbous nose, flat and elongated nasolabial furrow, thin hair and slow growth. Skeletal abnormalities that include short phalanges and metacarpals -brachydactyly-, cone-shaped epiphyses, hip dysplasia and short stature. Read More

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December 2018

A synaptic theory of internal delays.

J Acoust Soc Am 2018 Nov;144(5):2967

Department of Neuroscience, Erasmus MC, NL-3000 CA Rotterdam, The Netherlands.

Neurons in the medial superior olive perform a coincidence analysis between inputs from the two ears, as predicted by Jeffress [J. Comp. Psychol. Read More

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November 2018

Maternal Stress During Pregnancy Is Associated with Decreased Cortisol and Cortisone Levels in Neonatal Hair.

Horm Res Paediatr 2018 Dec 12:1-9. Epub 2018 Dec 12.

Department of Pediatric Endocrinology, VU University Medical Center, Amsterdam, The Netherlands.

Background: Hair glucocorticoids (GCs) offer a retrospective view on chronic GC exposure. We assessed whether maternal pre- and postnatal stress was associated with neonatal and maternal hair GCs postpartum (pp).

Methods: On the first day pp 172 mother-infant pairs donated hair, of whom 67 had consulted a centre of expertise for psychiatric disorders during pregnancy. Read More

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December 2018

Lower allergen levels in hypoallergenic Curly Horses? A comparison among breeds by measurements of horse allergens in hair and air samples.

PLoS One 2018 12;13(12):e0207871. Epub 2018 Dec 12.

Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Ruhr-Universität Bochum (IPA), Bochum, Germany.

Background: Exposure to horses can cause severe allergic reactions in sensitized individuals. The breed, American Bashkir Curly Horse is categorized as hypoallergenic, primarily due to reports of allergic patients experiencing fewer symptoms while handling this special breed. The possible reasons for this phenomenon could be lower allergen production and/or reduced allergen release into the air because of increased sebum content in their skin and hair compared to other breeds. Read More

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December 2018
2 Reads

Screen for modulators of atonal homolog 1 gene expression using notch pathway-relevant gene transcription based cellular assays.

PLoS One 2018 12;13(12):e0207140. Epub 2018 Dec 12.

R&D Alternative Discovery and Development, GlaxoSmithKline, Stevenage, Hertfordshire, United Kingdom.

Atonal homolog 1 (Atoh1) is a basic helix-loop-helix 9 (bHLH) transcription factor acting downstream of Notch and is required for the differentiation of sensory hair cells in the inner ear and the specification of secretory cells during the intestinal crypt cell regeneration. Motivated by the observations that the upregulation of Atoh1 gene expression, through genetic manipulation or pharmacological inhibition of Notch signaling (e.g. Read More

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December 2018

Hypohidrotic Ectodermal Dysplasia: A Rare Disorder with Bilateral Infantile Glaucoma.

J Glaucoma 2018 Dec 11. Epub 2018 Dec 11.

Glaucoma and anterior segment, Dr. Shroff's charity eye hospital, Delhi.

Ectodermal dysplasia is a disorder that occurs due to abnormalities of ectodermal structures such as skin, teeth, hair, nails, and eccrine glands. Approximately 200 different conditions have been identified as ectodermal dysplasia, the most common being hypohidrotic ectodermal dysplasia (HED). It is characterized by hypotrichosis (sparse scalp or body hair), hypodontia (absent or malformed teeth) and hypohidrosis (reduced ability to sweat). Read More

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December 2018
2 Reads

Sustainability in Biobanking.

Methods Mol Biol 2019 ;1897:1-6

Division of Neuropathology, Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.

Biobanks are storage places for biospecimens that can be used for current and future scientific research. Biospecimens are exceptional sources of biological data that can be potentially translated from molecular and genetic information to clinically relevant treatment modalities. Examples of such biospecimens include, but are not limited to, blood, skin, hair, saliva, stem cells, DNA, and RNA. Read More

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January 2019
1 Read

Heteroplasmy Detection of Mitochondrial DNA A3243G Mutation Using Quantitative Real-Time PCR Assay Based on TaqMan-MGB Probes.

Biomed Res Int 2018 13;2018:1286480. Epub 2018 Nov 13.

Chinovo Laboratory, Beijing, China.

A point mutation of mitochondrial DNA (mtDNA) at nucleotide position 3243 A to G (mt.3243A>G) is involved in many common diseases, including maternally inherited diabetes and deafness (MIDD) and mitochondrial encephalomyopathy, lactic acidosis with stroke-like episodes (MELAS). However, the mutant level of mt. Read More

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November 2018

Novel gene mutation in a patient with Menkes disease.

Appl Clin Genet 2018 22;11:151-155. Epub 2018 Nov 22.

Health Sciences Faculty, Universidad Icesi, Cali, Colombia,

Background: Menkes disease is a congenital neurodegenerative disorder caused by gene mutations. Clinical features include epilepsy, growth delay, reduced muscle strength, skin laxity, abnormal hair, and urologic abnormalities.

Case Presentation: We describe an infant with developmental delay, neurologic degeneration, and kinky hair. Read More

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November 2018
2 Reads

Investigation on spp. eggs in hair coat of dogs in YSR Kadapa district of Andhra Pradesh, India.

J Parasit Dis 2018 Dec 15;42(4):550-553. Epub 2018 Oct 15.

2Department of Veterinary Clinical Complex, College of Veterinary Science, Faculty of Veterinary Medicine, Sri Venkateswara Veterinary University, Proddatur, Andhra Pradesh 516 360 India.

Present study was aimed to record the spp. eggs in dog's hair and to analyze the incidence in breed and age wise along with incidence variations in the anatomical locations of hair over the body. Dogs presented to the hospital were screened for enteric parasitic ova and hair samples were collected from the different body regions including head and neck region, ventral and lateral abdomen, perianal and hindquarters and tail region. Read More

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December 2018

Protective Mechanism of Adipose-Derived Stem Cells in Remodelling of the Skin Stem Cell Niche During Photoaging.

Cell Physiol Biochem 2018 11;51(5):2456-2471. Epub 2018 Dec 11.

Background/aims: Skin photoaging is primarily caused by the functional attrition of skin stem cells. The skin stem cell niche plays an important role in maintaining stem cell survival and behaviour. In our study, we hypothesized that UVB irradiation induces skin photoaging by changing skin stem cell niches and that transferred adipose-derived stem cells (ADSCs) can remodel the niches by affecting the BMP signalling pathway and transdifferentiating into skin stem cells. Read More

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December 2018
3 Reads

Gonadotropin- and Adrenocorticotropic Hormone-Independent Precocious Puberty of Gonadal Origin in a Patient with Adrenal Hypoplasia Congenita Due to DAX1 Gene Mutation - A Case Report and Review of the Literature: Implications for the Pathomechanism.

Horm Res Paediatr 2018 Dec 11:1-10. Epub 2018 Dec 11.

Division of Pediatric Endocrinology and Diabetes, Department of Pediatrics and Adolescent Medicine, University of Ulm, Ulm, Germany.

Background/aims: Mutations in the DAX1 gene cause X-linked adrenal hypoplasia congenita (AHC) classically associated with hypogonadotropic hypogonadism. Unexpectedly, precocious puberty (PP) has been reported in some cases, its mechanism remaining unclear.

Methods: We longitudinally studied a boy with AHC due to DAX1 gene mutation who developed peripheral PP at age 4. Read More

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December 2018
1 Read

Regulation of melanocyte stem cells in the pigmentation of skin and its appendages: Biological patterning and therapeutic potentials.

Exp Dermatol 2018 Dec 11. Epub 2018 Dec 11.

Integrative Stem Cell Center, China Medical University Hospital, China Medical University, Taichung, 40402, Taiwan.

Skin evolves essential appendages and indispensable types of cells that synergistically insulate the body from environmental insults. Residing in the specific regions in the skin such as epidermis, dermis and hair follicle, melanocytes perform an array of vital functions including defending the ultraviolet radiation and diversifying animal appearance. As one of the adult stem cells, melanocyte stem cells in the hair follicle bulge niche can proliferate, differentiate, and keep quiescence to control and coordinate tissue homeostasis, repair, and regeneration. Read More

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December 2018
1 Read

Efficacy of topical dithranol (Dithrocream ) in the treatment of alopecia areata: a retrospective case series.

Authors:
A Daunton M Harries

Br J Dermatol 2018 Dec 10. Epub 2018 Dec 10.

The Dermatology Centre, Salford Royal NHS Foundation Trust, Salford, U.K.

Topical dithranol is an alternative therapy to topical diphencyprone for extensive AA, with the advantage that it can be applied at home. It is also safe in children and has low risk for use during pregnancy. Its precise mechanism of action is unknown, but it is plausible that the local cytokine profile induced by its irritant effect "compete" with the inflammatory milieu incited during the inflammatory cell attack on hair follicles. Read More

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December 2018
1 Read

Evaluation of long-term efficacy of finasteride in Korean men with androgenetic alopecia using the basic and specific classification system.

J Dermatol 2018 Dec 7. Epub 2018 Dec 7.

Department of Dermatology, Seoul National University Bundang Hospital, Seongnam, Korea.

Finasteride 1 mg is considered to be the standard treatment method for male androgenetic alopecia (AGA). However, there have only been a few studies investigating its long-term efficacy. Moreover, its effect on various types of AGA remains unknown. Read More

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December 2018

De novo and inherited loss-of-function variants of ATP2B2 are associated with rapidly progressive hearing impairment.

Hum Genet 2018 Dec 8. Epub 2018 Dec 8.

Hearing and Genes, Department of Otorhinolaryngology, Head and Neck Surgery, Radboud University Medical Center, Nijmegen, The Netherlands.

ATP2B2 encodes the PMCA2 Ca pump that plays an important role in maintaining ion homeostasis in hair cells among others by extrusion of Ca from the stereocilia to the endolymph. Several mouse models have been described for this gene; mice heterozygous for loss-of-function defects display a rapidly progressive high-frequency hearing impairment. Up to now ATP2B2 has only been reported as a modifier, or in a digenic mechanism with CDH23 for hearing impairment in humans. Read More

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December 2018
1 Read

Papillae formation on Arabidopsis leaf trichomes requires the function of Mediator tail subunits 2, 14, 15a, 16, and 25.

Planta 2018 Dec 7. Epub 2018 Dec 7.

School of Biological Sciences, Illinois State University, Normal, IL, 61790, USA.

Main Conclusion: Arabidopsis Mediator subunits 2, 14, 15a, 16, and 25 are required for papillae development on the trichome cell wall surface. Arabidopsis leaf hairs exhibit raised protrusions, termed papillae, on their cell wall surfaces. Here, we show that the glassy hair mutant, glh2, exhibits trichomes with an approximate 11-fold decrease in papillae density on their surfaces in comparison to wild type. Read More

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December 2018

A patient with pilomatricoma in the parotid region: case report and review of the literature.

Rom J Morphol Embryol 2018 ;59(3):917-926

Department of Histology, University of Medicine and Pharmacy of Craiova, Romania;

Pilomatricoma is a benign skin tumor originating from the matrix cells of the hair follicles. Sometimes, its diagnosis can be difficult, especially in the preauricular region, where in the differential diagnosis, in addition to other dermal and subcutaneous masses, primary and secondary parotid gland tumor lesions must be also considered. A 34-year-old female was referred to our Institution with a right preauricular swelling over 12 months, which enlarged in the last two months. Read More

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January 2018

Dry skin and the use of leave-on products in nursing care: A prevalence study in nursing homes and hospitals.

Nurs Open 2019 Jan 27;6(1):189-196. Epub 2018 Sep 27.

Department of Dermatology and Allergy, Clinical Research Center for Hair and Skin Science Charité - Universitätsmedizin Berlin Berlin Germany.

Aims: To describe the prevalence of dry skin in nursing homes and hospitals and to describe relationships between topical skincare interventions and dry skin.

Design: Two multicentre descriptive cross-sectional prevalence studies.

Methods: The studies were performed in German nursing homes and hospitals in 2015 and 2016. Read More

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January 2019

(Trichocomaceae): A Natural, Eco-Friendly Mycoinsecticide for Control of Malaria, Filariasis, Dengue Vectors and Its Toxicity Assessment Against an Aquatic Model Organism .

Front Pharmacol 2018 26;9:1355. Epub 2018 Nov 26.

Natural Drug Research Laboratory, Department of Biotechnology, School of Biosciences, Periyar University, Salem, India.

Vector-borne diseases like malaria, filariasis, and dengue are transmitted by mosquitoes and they cause global mortality and morbidity due to an increased resistance against commercial insecticides. The present study was aimed to evaluate the neurobehavioral toxicity, knock-down effect, histopathology, ovicidal, adulticidal, and smoke toxicity effect of extract against three mosquito species, namely , and (Diptera: Culicidae). The isolated fungal strain was identified as (GenBank accession no: KX694148. Read More

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November 2018

Comparative (Quantitative and Qualitative) Analysis of Three Different Reagents for Preparation of Platelet-Rich Plasma for Hair Rejuvenation.

Authors:
Sukhbir Singh

J Cutan Aesthet Surg 2018 Jul-Sep;11(3):127-131

Resplendent the cosmetic studio, R-9, GK Part 1, New Delhi-48.

Objective: The aim of this study was to compare the quantity and quality of platelets in platelet-rich plasma (PRP) samples prepared using three different reagents, namely, ethylenediaminetetraacetic acid (EDTA), sodium citrate, and acid citrate dextrose-A (ACD-A) solution.

Materials And Methods: A prospective study was carried out in which all the 50 patients who attended the outpatient department for hair rejuvenation were enrolled for the study. All the patients had a history of hair fall with diffuse thinning of hair, Norwood Grades 2 and 3. Read More

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December 2018