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    2817 results match your criteria Hair Transplantation

    1 OF 57

    Innovative modified hair follicle harvesting technique with reverse rake scalp elevator for lower occipital donor area in follicular unit extraction hair transplantation.
    Indian J Plast Surg 2016 Sep-Dec;49(3):390-396
    Department of Plastic Surgery, Grant Government Medical College and Sir J. J. Group of Hospitals, Mumbai, Maharashtra, India.
    Follicular unit extraction (FUE) is one of the widely practiced minimally invasive follicular harvesting techniques employed during hair transplantation. FUE technique has an advantage of utilising lower occipital area and supra-auricular region as a safe donor area described by Unger, in addition to the standard occipital donor area used in strip method (follicular unit transplant). Despite its potential advantages such as rapid recovery, minimal scarring and reduced post-operative pain; its widespread acceptance is limited due to various factors in variable contribution like steeper learning curve and potentially higher follicular transection rates (FTRs). Read More

    Enhanced Expansion and Sustained Inductive Function of Skin-Derived Precursor Cells in Computer-Controlled Stirred Suspension Bioreactors.
    Stem Cells Transl Med 2017 Feb 9;6(2):434-443. Epub 2016 Sep 9.
    Department of Comparative Biology and Experimental Medicine, Faculty of Veterinary Medicine, University of Calgary, Calgary, Alberta, Canada.
    Endogenous dermal stem cells (DSCs) reside in the adult hair follicle mesenchyme and can be isolated and grown in vitro as self-renewing colonies called skin-derived precursors (SKPs). Following transplantation into skin, SKPs can generate new dermis and reconstitute the dermal papilla and connective tissue sheath, suggesting they could have important therapeutic value for the treatment of skin disease (alopecia) or injury. Controlled cell culture processes must be developed to efficiently and safely generate sufficient stem cell numbers for clinical use. Read More

    Effect of Procedural-Related Variables on Melanocyte-Keratinocyte Suspension Transplantation in Nonsegmental Stable Vitiligo: A Clinical and Immunocytochemical Study.
    Dermatol Surg 2017 Feb;43(2):226-235
    Departments of *Dermatology, †Histology, and ‡Clinical Pathology, Kasr El-Ainy Teaching Hospital, Faculty of Medicine, Cairo University, Cario, Egypt.
    Background: Melanocyte-keratinocyte suspension (M-K susp) is gaining popularity for vitiligo treatment. Few studies have addressed procedure-related variables.

    Objective: To assess the effect of different M-K susp procedure-related variables on the clinical outcome in stable vitiligo. Read More

    Large Intragenic Deletion in DSTYK Underlies Autosomal-Recessive Complicated Spastic Paraparesis, SPG23.
    Am J Hum Genet 2017 Feb;100(2):364-370
    St John's Institute of Dermatology, King's College London (Guy's Campus), London SE1 9RT, UK; Centre for Dermatology and Genetic Medicine, Division of Molecular Medicine, University of Dundee, Dundee DD1 5EH, UK. Electronic address:
    SPG23 is an autosomal-recessive neurodegenerative subtype of lower limb spastic paraparesis with additional diffuse skin and hair dyspigmentation at birth followed by further patchy pigment loss during childhood. Previously, genome-wide linkage in an Arab-Israeli pedigree mapped the gene to an approximately 25 cM locus on chromosome 1q24-q32. By using whole-exome sequencing in a further Palestinian-Jordanian SPG23 pedigree, we identified a complex homozygous 4-kb deletion/20-bp insertion in DSTYK (dual serine-threonine and tyrosine protein kinase) in all four affected family members. Read More

    A case report of coup de sabre patient with hair transplantation.
    J Dermatolog Treat 2017 Jan 31:1-6. Epub 2017 Jan 31.
    b Tongde Hospital of Zhejiang Province , Hangzhou , China.
    Background: Treatment of coup de sabre must remain conservative until the disease is no longer in an active state. When activity has ceased, some operative intervention is safe and effective for the correction of deformity. While hair transplantation showed high survival rates for the correction of cicatricial alopecia, it has rarely reported to be performed for the correction of coup de sabre. Read More

    Evaluation of Quality of Life and Care Needs of Turkish Patients Undergoing Hematopoietic Stem Cell Transplantation.
    Nurs Res Pract 2016 26;2016:9604524. Epub 2016 Dec 26.
    Istanbul Bilim University Florence Nightingale Hospital School of Nursing, Yazarlar Sokak No. 17, Esentepe, Şişli, 34394 Istanbul, Turkey.
    This descriptive study explored the quality of life and care needs of Turkish patients who underwent hematopoietic stem cell transplantation. The study sample consisted of 100 hematopoietic stem cell transplant patients. Their quality of life was assessed using Functional Assessment of Cancer Therapy-Bone Marrow Transplant Scale. Read More

    Efficacy of 50 Hz electromagnetic fields on human epidermal stem cell transplantation seeded in collagen sponge scaffolds for wound healing in a murine model.
    Bioelectromagnetics 2017 Jan 20. Epub 2017 Jan 20.
    Department of Rehabilitation Medicine, Institute of Geriatric Medicine, Guangdong Academy of Medical Sciences, Guangdong General Hospital, Guangzhou, China.
    To explore the possible efficacy of electromagnetic fields (EMF) for skin tissue engineering, effects of EMF exposure on epidermal stem cells (ESC) seeded in collagen sponge scaffolds for wound healing in a murine model were investigated. The wound models of a full-thickness defect established with 36 7 ∼ 8-week-old nude mice were randomly divided into three groups: a control group, an ESC-only group, and an ESC with EMF exposure group (frequency of 50 Hz, magnetic induction of 5 mT, 60 min per day for 20 days). ESC were separated from human foreskin and cultured in vitro, and then transplanted with collagen sponge scaffolds as a delivery vehicle to wounds of the ESC-only group, and ESC with EMF exposure group was exposed to EMF after ESC transplantation. Read More

    Proliferation-independent regulation of organ size by Fgf/Notch signaling.
    Elife 2017 Jan 13;6. Epub 2017 Jan 13.
    Stowers Institute for Medical Research, Kansas City, United States.
    Organ morphogenesis depends on the precise orchestration of cell migration, cell shape changes and cell adhesion. We demonstrate that Notch signaling is an integral part of the Wnt and Fgf signaling feedback loop coordinating cell migration and the self-organization of rosette-shaped sensory organs in the zebrafish lateral line system. We show that Notch signaling acts downstream of Fgf signaling to not only inhibit hair cell differentiation but also to induce and maintain stable epithelial rosettes. Read More

    Fabrication of an Orbital Prosthesis Combined With Eyebrow Transplantation.
    J Craniofac Surg 2016 Dec 30. Epub 2016 Dec 30.
    *Department of Prosthodontics, Faculty of Dentistry, Okan University †Private Practice on Plastic Reconstructive and Aesthetic Surgery, Istanbul, Turkey.
    Fabrication of an orbital prosthesis is considered as a challenging procedure as compared to the other facial prosthesis due to the presence of inactive eye movements and the need of artificial hair in order to mimic eyelashes and eyebrows. Generally these structures are sewed or bonded in the silicone. However, deformation or hair loss is observed within time. Read More

    Pre-vascularization Enhances Therapeutic Effects of Human Mesenchymal Stem Cell Sheets in Full Thickness Skin Wound Repair.
    Theranostics 2017 1;7(1):117-131. Epub 2017 Jan 1.
    Department of Biomedical Engineering, Michigan Technological University, Houghton, Michigan, USA.
    Split thickness skin graft (STSG) implantation is one of the standard therapies for full thickness wound repair when full thickness autologous skin grafts (FTG) or skin flap transplants are inapplicable. Combined transplantation of STSG with dermal substitute could enhance its therapeutic effects but the results remain unsatisfactory due to insufficient blood supply at early stages, which causes graft necrosis and fibrosis. Human mesenchymal stem cell (hMSC) sheets are capable of accelerating the wound healing process. Read More

    A murine model of orthotopic periorbital subunit transplantation.
    Burns 2017 Mar 28;43(2):429-435. Epub 2016 Oct 28.
    Department of Plastic & Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, China. Electronic address:
    Background: Conventional reconstructive methods fail to achieve satisfactory results in total eyelid defect cases. Vascularized composite tissue allotransplantation might provide both good appearance and function for these patients. We developed an orthotopic periorbital transplantation model in rats to facilitate further experimentation in this field. Read More

    IBD-Like Features in Syndromic Diarrhea/Trichohepatoenteric Syndrome.
    J Pediatr Gastroenterol Nutr 2017 Jan;64(1):37-41
    *Pediatric Gastroenterology, Hepatology, and Liver Intestinal Transplantation Unit, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina †Nutrition et Gastroentérologie Pédiatriques, Hôpital Armand-Trousseau ‡UMR_S U1166 Nutriomics, UPMC, Sorbonne University, Paris, France §Pediatric Department, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina ||Département de Génétique Médicale, Hôpital de la Timone Enfant ¶UMR_S 910, Aix-Marseille Université #Service de Pédiatrie Multidisciplinaire, Hôpital de la Timone Enfant, Assistance Publique des Hôpitaux de Marseille, Marseille, France.
    Background: Very early onset inflammatory bowel disease (VEOIBD) (inflammatory bowel disease [IBD] before 6 years of age) may manifest as a monogenic disease affecting the gastrointestinal tract. Syndromic diarrhea/trichohepatoenteric syndrome (SD/THE), a rare disorder caused by alteration of a complex involved in RNA degradation, has been reported to present with some degree of colitis and in some cases an IBD-like presentation.

    Methods: We reviewed clinical and biological data of 4 previously published cases and added detailed data of 2 new cases of SD/THE with an IBD-like presentation. Read More

    Association Between Scalp Laxity, Elasticity, and Glidability and Donor Strip Scar Width in Hair Transplantation and a New Elasticity Measuring Method.
    Dermatol Surg 2016 Dec 21. Epub 2016 Dec 21.
    Dana Plastic Surgery Clinic, Seoul, Korea.
    Background: Hair transplantation requires precise evaluation of donor site laxity, elasticity, and glidability.

    Objective: The purpose of this study was to examine the relationship between donor strip scar width and preoperative laxity, elasticity, and glidability.

    Materials And Methods: Preoperative measurements of scalp laxity, elasticity, and glidability and of donor site scar width 10 months postoperatively were evaluated in 88 patients who underwent hair transplantation with strip harvesting. Read More

    Literature Review of Cosmetic Procedures in Men: Approaches and Techniques are Gender Specific.
    Am J Clin Dermatol 2017 Feb;18(1):87-96
    Department of Dermatology, Keck School of Medicine, University of Southern California, 1441 Eastlake Avenue, Ezralow Tower 5301, Los Angeles, CA, 90033, USA.
    The proportion of men receiving non-surgical cosmetic procedures has risen substantially in recent years. Various physiologic, anatomic, and motivational considerations differentiate the treatments for male and female patients. Nevertheless, research regarding approaches to the male cosmetic patient is scarce. Read More

    Preoperative evaluation and outcome of corneal transplantation for limbal dermoids: a ten-year follow-up study.
    Int J Ophthalmol 2016 18;9(12):1756-1760. Epub 2016 Dec 18.
    Shandong Eye Hospital, Shandong Eye Institute, Shandong Academy of Medical Sciences, Jinan 250021, Shandong Province, China.
    Aim: To summarize preoperative evaluation and outcome of corneal transplantation for limbal dermoids for ten years.

    Methods: Eighty-five patients diagnosed with limbal dermoids and treated with corneal transplantation were analyzed retrospectively. All patients were further divided into two groups according to absence or presence of neovascularization surrounding the dermoids in the corneal stroma. Read More

    Prenatal transplantation of epidermal neural crest stem cells in malformation of cortical development mouse model.
    Microsc Res Tech 2016 Dec 21. Epub 2016 Dec 21.
    Department of Anatomy, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
    Prenatal interventions may offer an immense opportunity in therapeutic protocols of malformations of cortical development (MCD). Epidermal neural crest stem cells (EPI-NCSCs) of the hair follicle bulge exhibit features of both embryonic and adult stem cells; these cells maintain their neurologic differentiation capability because of their neural crest origin. However, it is unknown if prenatal use of EPI-NCSCs could be beneficial in targeting methylazoxymethanol (MAM)-induced MCD, which further addressed in the present work. Read More

    Study of mouse induced pluripotent stem cell transplantation intoWistar albino rat cochleae after hair cell damage.
    Turk J Med Sci 2016 Nov 17;46(5):1603-1610. Epub 2016 Nov 17.
    Department of Pathology, Faculty of Medicine, Ankara University, Ankara, Turkey.
    Background/aim: As the regeneration capacity of hair cells is limited, inner ear stem cell therapies hold promise. Effects of mouse induced pluripotent stem cells (IPSCs) on Wistar albino rats (WARs) with hearing impairment were investigated.

    Materials And Methods: Thirty-five adult WARs with normal hearing were divided into 4 groups. Read More

    Comparative Study of Efficacy of Epidermal Melanocyte Transfer Versus Hair Follicular Melanocyte Transfer in Stable Vitiligo.
    Indian J Dermatol 2016 Nov-Dec;61(6):640-644
    Department of Dermatology and Venereology, Command Hospital Air Force, Bengaluru, Karnataka, India.
    Background: Vitiligo surgery has come up a long way from punch skin grafts to epidermal cell suspension and latest to the extracted hair follicle outer root sheath cell suspension (EHFORSCS) transplantation. The progressive development from one technique to the other is always on a quest for the best. In the latest development, EHFORSCS, which is an enriched source of follicular inactive melanocyte (melanocyte stem cells), seems to be a good addition to the prevailing cell-based therapies for vitiligo. Read More

    Towards a bacterial treatment for armpit malodour.
    Exp Dermatol 2016 Nov 28. Epub 2016 Nov 28.
    Center for Microbial Ecology and Technology (CMET), Ghent University, Gent, Belgium.
    Axillary malodour is a frustrating condition for many people. It can lead to significant discomforts and various psychological effects. The underarm microbiome plays a major role in axillary malodour formation. Read More

    Study on the Efficacy of Platelet-rich Fibrin Matrix in Hair Follicular Unit Transplantation in Androgenetic Alopecia Patients.
    J Clin Aesthet Dermatol 2016 Sep 1;9(9):29-35. Epub 2016 Sep 1.
    DiponEd BioIntelligence LLP, Bangalore, Karnataka, India.
    Objective: Hair loss is a significant problem worldwide. The most common cause of hair loss in men is male androgenetic alopecia, male pattern baldness, which is primarily due to the presence of nonfunctional or dead hair follicles in the scalp. Hair follicular unit transplantation has been a widely used technique to transplant hair follicles into bald areas. Read More

    Cryopreservation of Hair-Follicle Associated Pluripotent (HAP) Stem Cells Maintains Differentiation and Hair-Growth Potential.
    Adv Exp Med Biol 2016 ;951:191-198
    Department of Dermatology, Kitasato University, Sagamihara, Japan.
    Hair follicles contain nestin-expressing pluripotent stem cells which originate above the bulge area of the follicle, below the sebaceous gland. We have termed these cells hair follicle-associated pluripotent (HAP) stem cells. We have established efficient cryopreservation methods of the hair follicle that maintain the pluripotency of HAP stem cells as well as hair growth. Read More

    Study of frontal hairline patterns for natural design and restoration.
    Surg Radiol Anat 2016 Nov 10. Epub 2016 Nov 10.
    Department of Anatomy, Faculty of Medicine, Ege University, Izmir, Turkey.
    Objective: Hair loss is one of the most noticeable esthetic problems of the mankind. Hair transplantation has been a highly effective technique in reducing wide foreheads and recontouring the hairline. Creating a natural hairline is one of the most important elements of a successful hair transplant. Read More

    Development of a Novel Automated Hair Counting System for the Quantitative Evaluation of Laser Hair Removal.
    Photomed Laser Surg 2017 Feb 3;35(2):116-121. Epub 2016 Nov 3.
    5 Department of Biomedical Engineering, College of Medicine, Seoul National University , Seoul, Korea.
    Objective: We aimed to develop and validate a novel computer-assisted automated hair counting system for the quantitative evaluation of laser hair removal (LHR).

    Methods: We developed a computer-aided image processing system to count hairs on shaved skin and validated its performance through clinical trials. Five volunteers of Fitzpatrick skin type III-IV volunteered and were tested on both thighs. Read More

    Successful Treatment of Vitiligo on the Scalp of a 9-Year-Old Girl Using Autologous Cultured Pure Melanocyte Transplantation.
    Pediatr Dermatol 2017 Jan 4;34(1):e22-e23. Epub 2016 Nov 4.
    Department of Dermatology, Third People's Hospital of Hangzhou, Hangzhou, China.
    Leukotrichia frequently accompanies vitiligo on hairy areas such as the scalp. Treatment with conventional medical therapy is usually unsuccessful because of deficiencies in the melanocyte reservoir. We describe transplantation of autologous cultured pure melanocytes for scalp vitiligo with leukotrichia in a 9-year-old girl, resulting in almost complete and stable repigmentation of skin and hair. Read More

    Melanocytes from the outer root sheath of human hair and epidermal melanocytes display improved melanotic features in the niche provided by cGEL, oligomer-cross-linked gelatin-based hydrogel.
    J Biomed Mater Res A 2016 Dec 23;104(12):3115-3126. Epub 2016 Aug 23.
    Saxon Incubator for Clinical Translation/Translational Centre for Regenerative Medicine, Leipzig University, Phillip-Rosenthal-Str.55, Leipzig, 04103, Germany.
    Non-invasively based cell treatments of depigmented skin disorders are largely limited by means of cell sampling as much as by their routes of application. Human melanocytes cultivated from the outer root sheath of hair follicle (HUMORS) are among the cell types that fit the non-invasive concept by being cultivated out of a minimal sample: hair root. Eventual implementation of HUMORS as a graft essentially depends on a choice of suitable biocompatible, biodegradable carrier that would mechanically and biologically support the cells as transient niche and facilitate their engraftment. Read More

    The Kynurenine Pathway Is a Double-Edged Sword in Immune-Privileged Sites and in Cancer: Implications for Immunotherapy.
    Int J Tryptophan Res 2016 12;9:67-77. Epub 2016 Oct 12.
    Chronic Viral Illness Service, McGill University Health Centre, Montreal, QC, Canada.; Postdoctoral Fellow, The Research Institute of the McGill University Health Centre, Montreal, QC, Canada.
    The term "immune privilege" was originally coined to describe the suppression of inflammatory responses within organs protected by anatomic barriers, ie, the eyes, brain, placenta, and testes. However, cellular and metabolic processes, which orchestrate immune responses, also control inflammation within these sites. Our current understanding of tolerogenic mechanisms has extended the definition of immune privilege to include hair follicles, the colon, and cancer. Read More

    Comparative Study of a Novel Tool for Follicular Unit Extraction for Individuals with Afro-textured Hair.
    Plast Reconstr Surg Glob Open 2016 Sep 27;4(9):e1069. Epub 2016 Sep 27.
    Dermatology Division, Department of Medicine, University of California at Los Angeles, Calif.; and FineTouch Dermatology, Inc., Redondo Beach, Calif.
    Hair transplantation involving patients with tightly curled Afro-textured hair using follicular unit extraction (FUE) employing conventional rotary punches frequently leads to unacceptably high transection rates. These patients are unsuitable candidates for FUE hair transplantation. Transection rates were observed during FUE in a case series of 18 patients with tightly curled Afro-textured hair using different punches. Read More

    Body Hair Transplant by Follicular Unit Extraction: My Experience With 122 Patients.
    Aesthet Surg J 2016 Nov 30;36(10):1101-1110. Epub 2016 May 30.
    Dr Umar is a Clinical Instructor of Medicine, Department of Medicine, Division of Dermatology, University of California at Los Angeles, Los Angeles, CA.
    Background: Body hair shafts from the beard, trunk, and extremities can be used to treat baldness when patients have inadequate amounts of scalp donor hair, but reports in the literature concerning use of body hair to treat baldness are confined to case reports.

    Objectives: This study aimed to assess the outcome of body hair transplanted to bald areas of the scalp in selected patients.

    Methods: From 2005 through 2011, 122 patients preselected for adequate body hair had donor hair transplanted from the beard, trunk, and the extremities to the scalp by follicular unit extraction (FUE) by the author at a single center. Read More

    An Anatomical Murine Model of Heterotopic Periorbital Subunit Transplantation.
    Ophthal Plast Reconstr Surg 2016 Oct 13. Epub 2016 Oct 13.
    Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.
    Background: Conventional reconstructive methods fail to achieve satisfactory results in total eyelid defect cases. Vascularized composite tissue allotransplantation might provide both good appearance and function for these patients. The structure of the eyelid is exceptional because it simultaneously consists of skin, connective tissue, the striated muscle, fiber structure, aponeuroses, and mucosa. Read More

    Hair follicle-containing punch grafts accelerate chronic ulcer healing: A randomized controlled trial.
    J Am Acad Dermatol 2016 Nov;75(5):1007-1014
    Mediteknia Dermatology Clinic, Medical Pathology Group, University of Las Palmas de Gran Canaria, Gran Canaria, Spain. Electronic address:
    Background: A prominent role of hair follicle-derived cells in epidermal wound closure is now well established but clinical translation of basic research findings is scarce. Although skin punch grafts have been used as a therapeutic intervention to improve healing of chronic leg ulcers, they are normally harvested from nonhairy areas, thus not taking advantage of the reported role of the hair follicle as a wound-healing promoter.

    Objective: We sought to substantiate the role of hair follicles in venous leg ulcer healing by transplanting hair follicle-containing versus nonhairy punch grafts. Read More

    Allogeneic Hair Transplantation with Enhanced Survival by Anti-ICAM-1 Antibody with Short-Term Rapamycin Treatment in Nonhuman Primates.
    J Invest Dermatol 2017 Feb 7;137(2):515-518. Epub 2016 Oct 7.
    Department of Dermatology, Seoul National University College of Medicine, Seoul, Korea; Laboratory of Cutaneous Aging and Hair Research, Biomedical Research Institute, Seoul National University Hospital, Institute of Human-Environment Interface Biology, Medical Research Center, Seoul National University, Seoul, Korea. Electronic address:

    Cutaneous Mycobacterium abscessus infection following hair transplant.
    Clin Exp Dermatol 2016 Oct;41(7):768-70
    Department of Dermatology, Great Ormond Street Hospital, London, UK.
    A 28-year-old man presented with a 10-day history of scalp nodules. He had undergone hair transplantation 2 months previously. Incision and drainage of one of the nodules yielded gelatinous material, which was sent for microscopy and culture, including low-temperature culture. Read More

    A New Subtype of Lichen Planopilaris Affecting Vellus Hairs and Clinically Mimicking Androgenetic Alopecia.
    Dermatol Surg 2016 Oct;42(10):1174-80
    *American Board of Hair Restoration Surgery, Department of Dermatology, Abbasi Hair Clinic, Tehran, Iran; †Department of Dermatopathology, Razi Hospital, Tehran University of Medical Science, Tehran, Iran; ‡Department of Dermatology, Rasoul-e-Akram Hospital, Iran University of Medical Sciences, Tehran, Iran; §Department of Dermatology, Abbasi Hair Clinic, Tehran, Iran.
    Background: Lichen planopilaris (LPP) is a follicular variant of lichen planus. A new subtype of LPP mimicking androgenetic alopecia (AGA) may be misdiagnosed. Inappropriate medical therapy or hair transplantation may exacerbate this subtype. Read More

    Salvage urethroplasty using skin grafts for previously failed long-segment urethral strictures.
    Kaohsiung J Med Sci 2016 Sep 6;32(9):464-8. Epub 2016 Aug 6.
    Department of Urology, Medicana International Istanbul Hospital, Istanbul, Turkey.
    The aim of this study was to describe a technique using full-thickness skin grafts (FTSGs) from different parts of the body for salvage urethroplasties and the present outcomes. A total of 24 men underwent urethroplasties for strictures averaging 7.7 cm (range, 5-17 cm) in length, using FTSGs from the inner arm, inner thigh, or abdominal skin. Read More

    Masking the Close Eye Appearance in the East Asian Female Population: Infratemporal Hairline Reduction with Hair Grafting.
    Aesthetic Plast Surg 2016 Dec 8;40(6):921-925. Epub 2016 Sep 8.
    Dana Plastic Surgery Clinic, Human Tower 11F, Gangnamdaero 605, Seocho-gu, Seoul, Korea.
    Purpose: To investigate the effectiveness of hairline advancement in treating patients with perceived close-set eyes due to a wide infratemple area.

    Materials And Methods: Infratemple area hairline advancement was performed in 19 patients with perceived close-set eyes caused by a wide infratemple area; all were women with a mean age of 29.4 years. Read More

    The Effect of Ovine Secreted Soluble Factors on Human Dermal Papilla Cell Aggregation.
    Int J Trichology 2016 Jul-Sep;8(3):103-10
    Department of Medicine, University of Melbourne, Parkville, Australia; Department of Dermatology, Epworth Hospital, Melbourne, Australia.
    Context: In androgenetic alopecia, follicular miniaturization and dynamic changes to the hair cycle produce patterned baldness. The most effective treatment for baldness is hair transplantation surgery. The major limitation to hair transplantation is the availability of donor hair from the relatively unaffected occipital scalp. Read More

    Intellectual Disability: When the Hypertrichosis Is a Clue.
    J Pediatr Genet 2015 Sep 28;4(3):154-8. Epub 2015 Sep 28.
    Pediatric Highly Intensive Care Unit, Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy; Unit of Dermatology, Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy.
    The skin and the central and peripheral nervous system both derive from the ectoderm ridge. Therefore, several syndromes characterized by the presence of intellectual disability (ID) can be associated with specific congenital cutaneous manifestations. In this review, we list some of the most frequent diseases characterized by the presence of ID associated with hirsutism, which might be an incentive for the clinicians to pay attention to the ectodermal annexes in patients with ID. Read More

    Enhanced Expansion and Sustained Inductive Function of Skin-Derived Precursor Cells in Computer-Controlled Stirred Suspension Bioreactors.
    Stem Cells Transl Med 2016 Sep 9. Epub 2016 Sep 9.
    Department of Comparative Biology and Experimental Medicine, Faculty of Veterinary Medicine, University of Calgary, Calgary, Alberta, Canada Alberta Children's Hospital Research Institute, Calgary, Alberta, Canada Hotchkiss Brain Institute, Calgary, Alberta, Canada
    : Endogenous dermal stem cells (DSCs) reside in the adult hair follicle mesenchyme and can be isolated and grown in vitro as self-renewing colonies called skin-derived precursors (SKPs). Following transplantation into skin, SKPs can generate new dermis and reconstitute the dermal papilla and connective tissue sheath, suggesting they could have important therapeutic value for the treatment of skin disease (alopecia) or injury. Controlled cell culture processes must be developed to efficiently and safely generate sufficient stem cell numbers for clinical use. Read More

    Using Feily's method prevented scalp necrosis in three patients incline to the scalp recipient necrosis; what is new in prevention of scalp necrosis?
    Dermatol Ther 2017 Jan 9;30(1). Epub 2016 Sep 9.
    Department of Chemical treatment, Islamic, Azad University of Jahrom, Jahrom, Iran.
    Serious complications arising from surgical hair restoration are relatively uncommon following well-performed and well-planned surgery by skillful surgical techniques, good communication, and postoperative follow-up. Surgical complications often categorized as those which occur in the donor site and the recipient site. In this paper among recipient area complication we focused on recipient area necrosis that arises when an increased number of recipient grafts are utilized and de-vascularization of the scalp occurs as a result of the large wound area due to the dense packing splitting of recipient skin. Read More

    A Study of Noncultured Extracted Hair Follicle Outer Root Sheath Cell Suspension for Transplantation in Vitiligo.
    Int J Trichology 2016 Apr-Jun;8(2):67-72
    Department of Dermatology, NHL Medical College, V.S. General Hospital, Ahmedabad, Gujarat, India.
    Context: Vitiligo surgeries have come a long way from tissue grafts to cultured and non cultured cell transplantation. Extracted hair follicle outer root sheath cell transplantation (EHF ORS) suspension is more enriched with melanocyte. In a hair bulb, there is one melanocyte for every five keratinocytes which is much higher than the epidermal melanin unit. Read More

    Contributions of Mouse and Human Hematopoietic Cells to Remodeling of the Adult Auditory Nerve After Neuron Loss.
    Mol Ther 2016 Nov 7;24(11):2000-2011. Epub 2016 Sep 7.
    Department of Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston, South Carolina, USA.
    The peripheral auditory nerve (AN) carries sound information from sensory hair cells to the brain. The present study investigated the contribution of mouse and human hematopoietic stem cells (HSCs) to cellular diversity in the AN following the destruction of neuron cell bodies, also known as spiral ganglion neurons (SGNs). Exposure of the adult mouse cochlea to ouabain selectively killed type I SGNs and disrupted the blood-labyrinth barrier. Read More

    Hair Follicle Morphogenesis in the Treatment of Mouse Full-Thickness Skin Defects Using Composite Human Acellular Amniotic Membrane and Adipose Derived Mesenchymal Stem Cells.
    Stem Cells Int 2016 15;2016:8281235. Epub 2016 Aug 15.
    Department of Histology and Embryology, Second Military Medical University, Shanghai 200433, China.
    Early repair of skin injury and maximal restoration of the function and appearance have become important targets of clinical treatment. In the present study, we observed the healing process of skin defects in nude mice and structural characteristics of the new skin after transplantation of isolated and cultured adipose derived mesenchymal stem cells (ADMSCs) onto the human acellular amniotic membrane (AAM). The result showed that ADMSCs were closely attached to the surface of AAM and grew well 24 h after seeding. Read More

    Fractional CO2 Laser Pretreatment to Autologous Hair Transplantation and Phototherapy Improves Perifollicular Repigmentation in Refractory Vitiligo: A Randomized, Prospective, Half-Lesion, Comparative Study.
    Dermatol Surg 2016 Sep;42(9):1082-8
    *Department of Dermatology, Jahrom University of Medical Sciences, Jahrom, Iran; †Student Research Committee, Jahrom University of Medical Sciences, Jahrom, Iran; ‡Department of Radiation Oncology, SUNY Downstate Medical Center, New York.
    Background: Fractional CO2 laser and autologous hair transplantation are independently effective in the treatment of refractory and stable vitiligo.

    Objective: The authors' purpose was to evaluate the therapeutic efficacy of fractional CO2 laser pretreatment compared with autologous hair transplantation and phototherapy alone for refractory and stable vitiligo.

    Methods: A total of 20 patients with refractory and stable vitiligo were enrolled from our clinic. Read More

    5-Bromo-2'-deoxyuridine induced effluvium via p53-mediated CD326-positive keratinocyte apoptosis in C57BL/6 mice.
    J Dermatol 2016 Aug 20. Epub 2016 Aug 20.
    Graduate School of International Agricultural Technology, Seoul National University, Pyeongchang, Korea.
    Anagen effluvium develops because of disturbances in the hair follicle cycle, leading to acute and severe hair loss in humans. The objective of this study was to establish a mouse model of anagen effluvium by 5-bromo-2'-deoxyuridine (BrdU) treatment, and evaluate the pathological changes and underlying mechanisms. We treated 9-10-day-old pups and 3-7-week-old C57BL/6 mice with BrdU. Read More

    DNA profiling in blood, buccal swabs, and hair follicles of transplantation patients.
    Turk J Med Sci 2016 Jun 23;46(4):1177-81. Epub 2016 Jun 23.
    Department of Legal Medicine, Faculty of Medicine, Dokuz Eylül University, İzmir, Turkey.
    Background/aim: Peripheral blood DNA profiles are often used in forensic identification and paternity investigations. Currently, because of the increasing number of patients who undergo transplantation, determining the history of transplantation has gained importance in forensic cases. The aim of this study was to investigate the potential of genetic chimerism analysis of blood, hair follicle, and buccal swab samples for the forensic identification of transplant patients. Read More

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