4,894 results match your criteria HPB Surgery [Journal]


Perioperative Antithrombotic Therapy Does Not Increase the Incidence of Early Postoperative Thromboembolic Complications and Bleeding in Kidney Transplantation. - a retrospective study.

Transpl Int 2018 Dec 10. Epub 2018 Dec 10.

Division of Transplantation Surgery, Department of Surgery, University of Groningen, University Medical Center Groningen, the Netherlands.

Perioperative antithrombotic therapy could play a role in preventing thromboembolic complications (TEC) after kidney transplantation (KTx), but little is known on postoperative bleeding risks. This retrospective analysis comprises 2000 single-organ KTx recipients transplanted between 2011-2016 in the two largest transplant centers of the Netherlands. TEC and bleeding events were scored ≤7 days post-KTx. Read More

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December 2018

Thirty days are inadequate for assessing readmission following complex hepatopancreatobiliary procedures.

Surg Endosc 2018 Dec 10. Epub 2018 Dec 10.

Division of Bariatric, Foregut and Advanced Gastrointestinal Surgery, Department of Surgery, Stony Brook University Medical Center, 100 Nichols Road, HSC T18-040, Stony Brook, 11794, NY, USA.

Introduction: Early readmissions (30 days) have been used as a measure of health care quality. The purpose of our study was to evaluate patterns of readmission for a longer period (up to 2 years) following Hepatopancreatobiliary (HPB) surgery in the state of New York.

Methods: The State Planning and Research Cooperative System database was utilized to identify patients undergoing complex HPB procedures between 2010 and 2012. Read More

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December 2018
1 Read

Perioperative monitoring of intracranial pressure using optic nerve sheath diameter in paediatric liver transplantation.

Indian J Anaesth 2018 Nov;62(11):892-895

Apollo LT and HPB Surgery, Indraprastha Apollo Hospitals, New Delhi, India.

An elevation of intracranial pressure (ICP) secondary to cerebral oedema is a major contributor to morbidity and mortality in acute liver failure (ALF). We present a case of ICP monitoring with ocular ultrasonography in a 2-year-old child with ALF for liver transplantation. Since invasive ICP monitoring was risky considering the level of coagulopathy, optic nerve sheath diameter (ONSD) monitoring was done by ultrasound. Read More

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November 2018

A Three-dimensional scaffold from decellularized human umbilical artery for bile duct reconstruction.

Ann Ital Chir 2018 Dec 5;7. Epub 2018 Dec 5.

cord artery and use it to reconstruct common bile duct obstruction with preservation of sphincter of Oddi.

Material And Methods: SDS and Triton X-100 were used for decellularization of the artery. Allogeneic isolated cholangiocytes were seeded onto the inner surface of the decellularized artery. Read More

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December 2018

Age-related risks of complications after distal pancreatectomy for neuroendocrine and cystic neoplasms.

HPB (Oxford) 2018 Dec 7. Epub 2018 Dec 7.

Department of Surgery, Virginia Commonwealth University Medical Center, Richmond, VA, USA. Electronic address:

Background: Distal pancreatic neuroendocrine tumors (PNET) and pancreatic cystic neoplasms (PCN) are often incidentally found in older adults, requiring careful consideration between operative management and watchful waiting. This study analyzes the short-term complications associated with distal pancreatectomy (DP) for PNET and PCN in older adults to inform clinical decision-making.

Methods: Patients undergoing DP for PNET and PCN were analyzed using the American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) database and the pancreatectomy procedure-targeted dataset. Read More

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December 2018

Laparoscopic pancreatoduodenectomy with open or laparoscopic reconstruction during the learning curve: a multicenter propensity score matched study.

HPB (Oxford) 2018 Dec 4. Epub 2018 Dec 4.

Department of Surgery, Cancer Center Amsterdam, Amsterdam UMC, University of Amsterdam, The Netherlands. Electronic address:

Background: Laparoscopic pancreatoduodenectomy with open reconstruction (LPD-OR) has been suggested to lower the rate of postoperative pancreatic fistula reported after laparoscopic pancreatoduodenectomy with laparoscopic reconstruction (LPD). Propensity score matched studies are, lacking.

Methods: This is a multicenter prospective cohort study including patients from 7 Dutch centers between 2014-2018. Read More

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December 2018

Management of asymptomatic, well-differentiated PNETs: results of the Delphi consensus process of the Americas Hepato-Pancreato-Biliary Association.

HPB (Oxford) 2018 Dec 5. Epub 2018 Dec 5.

Department of Surgery, Sunnybrook Health Sciences Centre, Toronto, ON, USA.

Background: Variation in the management of PNETs exist due to the limited high-level evidence to guide clinical practice. The aim of this work is to generate consensus guidelines with a Delphi process for managing PNETs.

Methods: A panel of experts reviewed the surgical literature and scored a set of clinical case statements using a web-based survey to identify areas of agreement and disagreement. Read More

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December 2018

Contemporary practice and short-term outcomes after liver resections in a complete national cohort.

Langenbecks Arch Surg 2018 Dec 5. Epub 2018 Dec 5.

Clinical Surgery, Royal Infirmary of Edinburgh and University of Edinburgh, Edinburgh, UK.

Background: Improved outcome after liver resections have been reported in several series, but outcomes from national cohorts are scarce. Our aim was to evaluate nationwide practice and short-term outcomes after liver surgery in a universal healthcare system.

Methods: A complete 5-year cohort of all liver resections from the Norwegian Patient Registry (NPR). Read More

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December 2018
2 Reads

Demographic and facility volume related outcomes in radiofrequency ablation for early-stage hepatocellular carcinoma.

HPB (Oxford) 2018 Dec 3. Epub 2018 Dec 3.

University of California, Irvine School of Medicine, Department of Radiological Sciences, 101 The City Drive South, Orange, CA 92868, USA.

Background: To evaluate outcomes related to disparities in facility volume and patient demographics in patients with early-stage hepatocellular carcinoma (HCC) treated with radiofrequency ablation (RFA).

Methods: This is a retrospective study of patients with stage I/II HCC treated with RFA in the National Cancer Database. Independent contributors to overall survival were determined with Cox regression analysis. Read More

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December 2018

Liver microwave ablation: a systematic review of various FDA-approved systems.

Eur Radiol 2018 Nov 30. Epub 2018 Nov 30.

Department of HPB Surgery and Liver Transplantation, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.

Objectives: The aim of the present study is to analyze preclinical and clinical data on the performance of the currently US Food and Drug Administration (FDA)-approved microwave ablation (MWA) systems.

Methods: A review of the literature, published between January 1, 2005, and December 31, 2016, on seven FDA-approved MWA systems, was conducted. Ratio of ablation zone volume to applied energy R(AZ:E) and sphericity indices were calculated for ex vivo and in vivo experiments. Read More

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November 2018

Double cholecystectomy in case of accessory gallbladder: Not as easy as two cholecystectomies.

Hepatobiliary Pancreat Dis Int 2018 Nov 24. Epub 2018 Nov 24.

Department of General Surgery and Liver Transplantation, Hospices Civils de Lyon, Croix-Rousse University Hospital, Lyon, France; Ecole Doctorale EDISS 205, Université Lyon 1, EMR 3738, Lyon, France.

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November 2018
1 Read

Lower phosphate levels following pancreatectomy is associated with postoperative pancreatic fistula formation.

HPB (Oxford) 2018 Nov 29. Epub 2018 Nov 29.

Harvard Medical School, 25 Shattuck St., Boston, MA 02115, USA; Massachusetts General Hospital, 55 Fruit St., Boston, MA 02114, USA. Electronic address:

Background: Whereas hypophosphatemia following hepatectomy is associated with decreased morbidity, hypophosphatemia following pancreatectomy may be associated with increased morbidity, including the development of postoperative pancreatic fistula (POPF). This study aimed to evaluate the relationship between postoperative hypophosphatemia and POPF formation.

Methods: Patients from our institutional Research Patient Data Registry who underwent pancreatectomy from 2001 to 2017 were included. Read More

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November 2018

Living or deceased organ donors in liver transplantation for hepatocellular carcinoma: a systematic review and meta-analysis.

HPB (Oxford) 2018 Nov 29. Epub 2018 Nov 29.

Department of Liver Surgery & Liver Transplantation Center, West China Hospital, Sichuan University, Chengdu, 610041, China; Laboratory of Liver Surgery, West China Hospital, Sichuan University, Chengdu, 610041, China. Electronic address:

Background: The outcomes of living donor liver transplantation (LDLT) versus deceased donor liver transplantation (DDLT) for HCC patients were not well defined and it was necessary to reassess.

Methods: A comprehensive literature search was conducted in PubMed, Embase, Cochrane Library, Google Scholar and WanFang database for eligible studies. Perioperative and survival outcomes of HCC patients underwent LDLT were pooled and compared to those underwent DDLT. Read More

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November 2018

Tweeting the meeting: Quantitative and qualitative twitter activity during the 38th ESSO conference.

Eur J Surg Oncol 2018 Nov 24. Epub 2018 Nov 24.

Department of Surgery, Hospital Clinico San Carlos de Madrid, Instituto de Investigación Sanitaria San Carlos, Universidad Complutense de Madrid, Martín-Lagos, S/N, 28040, Madrid, Spain.

Introduction: Social media is increasingly used to share information with the potential for fast and wide reach. Data on use during surgical oncology conferences is limited. We aimed to monitor twitter usage during a surgical oncology conference to audit impact of activity. Read More

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November 2018

The impact of resection margin on overall survival for patients with colon cancer liver metastasis varied according to the primary cancer location.

HPB (Oxford) 2018 Nov 27. Epub 2018 Nov 27.

Department of General Surgery, Digestive Disease and Surgery Institute, Cleveland Clinic, Cleveland, OH, USA. Electronic address:

Introduction: Investigation into right and left-sided primary colon liver metastasis (CLM) has revealed differences in the tumor biology and prognosis. This indicates that preoperative and operative factors may affect outcomes of right-sided primary CLM differently than left. This retrospective analysis investigated the effects of resection margin stratified by left and right-sided primary CLM on overall survival (OS) for patients undergoing hepatectomy. Read More

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November 2018

Hypovolemic phlebotomy in liver surgery is associated with decreased red blood cell transfusion.

HPB (Oxford) 2018 Nov 27. Epub 2018 Nov 27.

Liver and Pancreas Unit, Department of Surgery, The Ottawa Hospital, University of Ottawa, Ottawa, ON, Canada; Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, ON, Canada. Electronic address:

Background: Perioperative red blood cell (RBC) transfusion is associated with poor outcomes in liver surgery. Hypovolemic phlebotomy (HP) is a novel intervention hypothesized to decrease transfusion requirements. The objective of this study was to examine this hypothesis. Read More

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November 2018
7 Reads
2.050 Impact Factor

Can post-hoc video review of robotic pancreaticoduodenectomy predict portal/superior mesenteric vein margin status in pancreatic adenocarcinoma?

HPB (Oxford) 2018 Nov 27. Epub 2018 Nov 27.

Department of Surgery, University of Pittsburgh Medical Center, 5150 Center Ave, Pittsburgh, PA 15232, USA; Department of Surgery, West Virginia University, PO Box 9238 HSCS, Morgantown, WV 26506, USA. Electronic address:

Background: Achieving margin negative resection is a significant determinant of outcome in pancreatic adenocarcinoma (PDA). However, because of the fibrotic nature of PDA, it can be difficult to discriminate fibrosis from active disease intra-operatively. We sought to determine if post-hoc video review of robotic pancreatico-duodenectomy (RPD) could predict the portal/superior mesenteric vein (PV/SMV) margin status on final pathology. Read More

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November 2018
3 Reads

Perioperative blood transfusions for vein resection during pancreaticoduodenectomy for pancreatic adenocarcinoma: Identification of clinical targets for optimization.

HPB (Oxford) 2018 Nov 27. Epub 2018 Nov 27.

Department of Surgical Oncology, University of Texas MD Anderson Cancer Center, USA. Electronic address:

Background: Perioperative blood transfusion (PBT) during resection of pancreatic adenocarcinoma (PDAC) has been linked to worse short-term and oncologic outcomes. However, little is known about contemporary rates of transfusion utilization among patients requiring pancreaticoduodenectomy with vein resection (PDVR). The primary aims of this study were to evaluate rates of PBT and to identify modifiable factors associated with PBT during PDVR. Read More

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November 2018

Prevalence of Steatosis Hepatis in the Region: Impact on Graft Acceptance Rates.

HPB Surg 2018 1;2018:6094936. Epub 2018 Nov 1.

Department of Surgery, Campus Charité Mitte ∣ Campus Virchow-Klinikum, Experimental Surgery and Regenerative Medicine, Charité - Universitätsmedizin Berlin 13353, Germany.

Due to the shortage of liver allografts and the rising prevalence of fatty liver disease in the general population, steatotic liver grafts are considered for transplantation. This condition is an important risk factor for the outcome after transplantation. We here analyze the characteristics of the donor pool offered to the from 2010 to 2016 with respect to liver allograft nonacceptance and steatosis hepatis. Read More

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November 2018

Underutilization of surgical resection in patients with pancreatic acinar cell carcinoma.

HPB (Oxford) 2018 Dec 1. Epub 2018 Dec 1.

Duke University Medical Center, Department of Surgery, Durham, NC, USA. Electronic address:

Background: Pancreatic acinar cell carcinoma (pACC) is a rare malignancy and surgical utilization has been historically low in these patients. Contemporary outcomes for this patient population remain unknown.

Methods: The 1998-2012 National Cancer Data Base was queried for baseline characteristics in patients with pACC. Read More

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December 2018
1 Read

Modulation of Human Complement System by Antimicrobial Peptide Arenicin-1 from .

Mar Drugs 2018 Dec 1;16(12). Epub 2018 Dec 1.

Institute of Experimental Medicine, Acad. Pavlov Str. 12, Saint Petersburg 197376, Russia.

Antimicrobial peptides from marine invertebrates are known not only to act like cytotoxic agents, but they also can display some additional activities in mammalian organisms. In particular, these peptides can modulate the complement system as was described for tachyplesin, a peptide from the horseshoe crab. In this work, we investigated the influence on complement activation of the antimicrobial peptide arenicin-1 from the marine polychaete . Read More

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December 2018

International publication trends in hepato-pancreato-biliary surgery: emergency compared to oncology.

ANZ J Surg 2018 Dec 4. Epub 2018 Dec 4.

Sydney Medical School, The University of Sydney, Sydney, New South Wales, Australia.

Background: There is growing interest in publishing trends given the increasing amount of research publication across various specialities. Studies relating to hepato-pancreato-biliary (HPB) surgery show an oncological focus compared to benign, emergency and trauma.

Methods: Analysis of ISI JCR impact factors in the Web of Knowledge and the Scimago Journal Rank through Scopus was performed to select four readily available, relevant and frequently read journals from the surgery category. Read More

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December 2018
4 Reads

Does IgG4 level at the time of diagnosis correlate with disease outcome in IgG4-Related disease?

Pancreatology 2018 Oct 29. Epub 2018 Oct 29.

HPB Unit, Freeman Hospital, Freeman Road, Newcastle Upon Tyne, NE7 7DN, UK. Electronic address:

Background/objectives: Serum IgG4 level is used as a diagnostic criterion for immunoglobulin G4-related disease (IgG4-RD) but whether it predicts disease progression is unclear. Aim of the study was to investigate if serum IgG4 level at the time of diagnosis correlates with disease outcome.

Methods: Patients with a definitive diagnosis of IgG4-RD were included in this study. Read More

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October 2018

Does robotic pancreaticoduodenectomy improve outcomes in patients with high risk morphometric features compared to the open approach.

HPB (Oxford) 2018 Nov 30. Epub 2018 Nov 30.

Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA. Electronic address:

Background: We sought to investigate whether robotic pancreatoduodenectomy (RPD) mitigates adverse outcomes in patients with high-risk morphometric features compared to the open approach (OPD).

Methods: Morphometric parameters for RPD and OPDs were measured by two blinded radiologists. The morphometric parameter best correlating with adverse outcomes was identified and used in multivariable models to evaluate the impact of surgical approach (open vs. Read More

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November 2018
5 Reads

Highlights in this issue.

Authors:

HPB (Oxford) 2018 Dec;20(12):iv

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December 2018

Hot spotting surgical patients undergoing hepatopancreatic procedures.

HPB (Oxford) 2018 Nov 26. Epub 2018 Nov 26.

Department of Surgery, The Ohio State University Wexner Medical Center, Columbus, OH, USA. Electronic address:

Background: The burden of health care spending in the United States is a major concern, as health care costs have exponentially increased during the last three decades. The objective of the current study was to investigate the degree of cost-concentration among Medicare patients undergoing liver and pancreatic surgery.

Methods: Medicare claims data from 2013 to 2015 were used to identify patients undergoing elective liver and pancreatic resections. Read More

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November 2018
1 Read

Perioperative blood transfusions following hepatic lobectomy: A national analysis of academic medical centers in the modern era.

HPB (Oxford) 2018 Nov 26. Epub 2018 Nov 26.

Cincinnati Research in Outcomes and Safety in Surgery (CROSS), Department of Surgery, University of Cincinnati College of Medicine, Cincinnati, OH, USA. Electronic address:

Background: The purpose of the study was to characterize the prevalence and impact of perioperative blood use for patients undergoing hepatic lobectomy at academic medical centers.

Methods: The University HealthSystem Consortium (UHC) database was queried for hepatic lobectomies performed between 2011 and 2014 (n = 6476). Patients were grouped according to transfusion requirements into high (>5 units, 7%), medium (2-5 units, 6%), low (1 unit, 8%), and none (0 units, 79%) during hospital stay for comparison of outcomes. Read More

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November 2018

Letter: the effect of sirolimus on recurrence and survival in liver transplant recipients with hepatocellular carcinoma-authors' reply.

Aliment Pharmacol Ther 2018 Dec;48(11-12):1331-1332

Institute of Liver Studies, King's College Hospital, London, UK.

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December 2018

Performance validation of the ALPPS risk model.

HPB (Oxford) 2018 Nov 23. Epub 2018 Nov 23.

Swiss HPB and Transplantation Center, Department of Surgery, University Hospital Zurich, Switzerland. Electronic address:

Background: Based on the International ALPPS registry, we have recently proposed two easily applicable risk models (pre-stage1 and 2) for predicting 90-day mortality in ALPPS but a validation of both models has not been performed yet.

Methods: The validation cohort (VC) was composed of subsequent cases of the ALPPS registry and cases of centers outside the ALPPS registry.

Results: The VC was composed of a total of 258 patients including 70 patients outside the ALPPS registry with 32 cases of early mortalities (12%). Read More

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November 2018
2 Reads

Different approaches to liver transplantation in propionic acidemia patients.

Liver Transpl 2018 Nov 24. Epub 2018 Nov 24.

HPB Surgery and Transplants Department, Hospital Universiatri Vall d'Hebron, Barcelona, Spain.

We thank Rammohan et cols for the comment on our paper entitled "The Role of Liver Transplantation in Propionic Acidemia". As the authors highlight, the reported rates of Hepatic Arterial Thrombosis (HAT) in Propionic Acidemia (PA) patients that undergo Liver Transplantation (LT) are higher than in other indications of LT (1). As described in the paper, the rate of HAT in our series is 33% (2/6) similar to those reported by other groups (1-2). Read More

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November 2018
1 Read

Crowdsourced Assessment of Inanimate Biotissue Drills: A Valid and Cost-Effective Way to Evaluate Surgical Trainees.

J Surg Educ 2018 Nov 21. Epub 2018 Nov 21.

Department of Surgery, Northshore University HealthSystem, Chicago, Illinois. Electronic address:

Objective: Providing feedback to surgical trainees is a critical component for assessment of technical skills, yet remains costly and time consuming. We hypothesize that statistical selection can identify a homogenous group of nonexpert crowdworkers capable of accurately grading inanimate surgical video.

Design: Applicants auditioned by grading 9 training videos using the Objective Structured Assessment of Technical Skills (OSATS) tool and an error-based checklist. Read More

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November 2018

Neoadjuvant therapy and major arterial resection for potentially reconstructable arterial involvement by stage 3 adenocarcinoma of the pancreas.

HPB (Oxford) 2018 Nov 21. Epub 2018 Nov 21.

Department of Surgery, University Health Network, University of Toronto, Toronto, Canada; University of Toronto, Toronto, Canada. Electronic address:

Background: Stage 3 pancreatic ductal adenocarcinoma (PDAC) is defined by arterial involvement. This study objective was to evaluate outcomes for patients with stage 3 PDAC with potentially reconstructable arterial involvement, considered for neoadjuvant therapy (NAT) and pancreatic resection, and to compare outcomes following arterial (AR) and non-arterial resection (NAR).

Methods: This study included patients from 2009 to 2016 with biopsy-proven stage 3 PDAC who were offered NAT before surgical exploration. Read More

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November 2018
6 Reads

CA19.9 decrease >15% is a predictor of favourable outcome in patients treated for advanced pancreatic carcinoma: analysis of two independent cohorts.

HPB (Oxford) 2018 Nov 19. Epub 2018 Nov 19.

Normandie Univ, UNIROUEN, Inserm U1245, IRON Group, Rouen University Hospital, Digestive Oncology Unit and Department of Medical Oncology, Henri Becquerel Centre, Rouen, F 76000, Rouen, France. Electronic address:

Background: Although carbohydrate antigen 19.9 (CA19.9) is widely used in pancreatic adenocarcinoma (PA), no consensual cut-off value of CA19. Read More

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November 2018
3 Reads

ASO Author Reflections: Is It Important to Do Exercise Before Surgery for HPB Malignancy?

Ann Surg Oncol 2018 Nov 21. Epub 2018 Nov 21.

Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan.

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November 2018
1 Read

Fluxional motion in a dinuclear copper(i) complex with a propeller-type ligand: metal hopping on both sides.

Dalton Trans 2018 Dec 22;47(48):17206-17210. Epub 2018 Nov 22.

Department of Chemistry, Pohang University of Science and Technology, 77 Cheongam-Ro, 37673, Pohang, Republic of Korea. and Division of Advanced Materials Science, Pohang University of Science and Technology, 77 Cheongam-Ro, 37673, Pohang, Republic of Korea.

The first study of fluxional motion in [Cu(2-HPB)(MeCN)Cl] (1,2-HPB = hexa(2-pyridyl)benzene) is presented. For detailed examination of the fluxional motion mechanism, a monofluorinated derivative of the ligand (MFHPB) and its copper(i) complexes were synthesized and characterized. The solution NMR studies of monofluoro copper(i) complex 1a suggest the existence of five species in equilibrium. Read More

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December 2018

Laparoscopic duodenum-preserving total pancreatic head resection: a novel surgical approach for benign or low-grade malignant tumors.

Surg Endosc 2018 Nov 19. Epub 2018 Nov 19.

Department of Hepatobiliopancreatic Surgery, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Yanjiangxi Road 107#, Guangzhou, China.

Background: Duodenum-preserving total pancreatic head resection (DPPHRt) is an accepted alternative surgical procedure for benign or low-grade malignant tumors of the pancreatic head by preserving the duodenum with its intact blood supply from the pancreatic duodenal arterial arcade. This study describes our experience in laparoscopic DPPHRt (LDPPHRt). To our knowledge, this is the first description of this novel minimally invasive operation. Read More

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November 2018
3 Reads

Anastomotic reconstruction and external drainage of Wirsung's duct as treatment for pancreaticojejunal stenosis following pancreaticoduodenectomy.

Cir Esp 2018 Nov 15. Epub 2018 Nov 15.

Unidad de Cirugía HPB y Trasplante de Órganos Abdominales, Hospital Universitario 12 de Octubre, Madrid, España; Departamento de Cirugía de la Facultad de Medicina, Universidad Complutense de Madrid, Madrid, España.

Stenosis of the pancreaticodigestive anastomosis (pancreaticogastrostomy and pancreaticojejunostomy) is a very rare complication that usually develops several years after pancreaticoduodenectomy (PD). Only a few cases have been previously reported. We have reviewed the literature and present 2 more cases of pancreaticojejunostomy stenosis that started with episodes of recurrent acute pancreatitis 6 years and 1 year after PD, respectively. Read More

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November 2018
10 Reads

Patient blood management for liver resection: consensus statements using Delphi methodology.

HPB (Oxford) 2018 Nov 13. Epub 2018 Nov 13.

Department of Surgery, Odette Cancer Centre - Sunnybrook Health Sciences Centre, Toronto, ON, Canada; Department of Surgery, University of Toronto, Toronto, ON, Canada.

Background: Blood loss and transfusion remain a significant concern in liver resection (LR). Patient blood management (PBM) programs reduce use of transfusions and improve outcomes and costs, but are not standardized for LR. This study sought to create an expert consensus statement on PBM for LR using modified Delphi methodology. Read More

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November 2018
1 Read

Does attending a Delphi consensus conference impact surgeon attitudes? Survey results from the Americas HepatoPancreatoBiliary Association consensus conference on small asymptomatic pancreatic neuroendocrine tumors.

HPB (Oxford) 2018 Nov 12. Epub 2018 Nov 12.

Department of Surgery, UT Southwestern, Dallas, TX, USA.

Background: Management of asymptomatic small well-differentiated (panNET) <2 cm remains controversial. A consensus conference was held on this topic. The impact of attending the conference and participating in the audience response survey on surgeon's clinical approach to pancreatic neuroendocrine tumors was assessed. Read More

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November 2018

Laparoscopic Transcystic Common Bile Duct Exploration in the Emergency Is as Effective and Safe as in Elective Setting.

J Gastrointest Surg 2018 Nov 12. Epub 2018 Nov 12.

Department of General Surgery, Division of HPB Surgery, Hospital Italiano de Buenos Aires, Juan D. Peron 4190, C1181ACH, Buenos Aires, Argentina.

Background: Emergent laparoscopic transcystic common bile duct exploration (LTCBDE) has been reported to be on the increase in some institutions, reflecting the growing confidence with the technique. However, no study has focused on the outcomes of LTCBDE in the non-elective setting. The aim of this study is to investigate whether LTCBDE can be performed effectively and safely in the emergency. Read More

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November 2018
5 Reads

Robotic-assisted versus laparoscopic left pancreatectomy at a high-volume, minimally invasive center.

Surg Endosc 2018 Nov 12. Epub 2018 Nov 12.

Division of HPB Surgery, Department of Surgery, Carolinas Medical Center, Charlotte, NC, USA.

Introduction: While minimally invasive left pancreatectomy has become more widespread and generally accepted over the last decade, opinions on modality of minimally invasive approach (robotic or laparoscopic) remain mixed with few institutions performing a significant portion of both operative approaches simultaneously.

Methods: 247 minimally invasive left pancreatectomies were retrospectively identified in a prospectively maintained institutional REDCap™ database, 135 laparoscopic left pancreatectomy (LLP) and 108 robotic-assisted left pancreatectomy (RLP). Demographics, intraoperative variables, postoperative outcomes, and OR costs were compared between LLP and RLP with an additional subgroup analysis for procedures performed specifically for pancreatic adenocarcinoma (35 LLP and 23 RLP) focusing on pathologic outcomes and 2-year actuarial survival. Read More

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November 2018
6 Reads

Proposal of Two Prognostic Models for the Prediction of 10-Year Survival after Liver Resection for Colorectal Metastases.

HPB Surg 2018 21;2018:5618581. Epub 2018 Oct 21.

General, Visceral and Transplantation Surgery, Hannover Medical School, Germany.

Background: One-third of 5-year survivors after liver resection for colorectal liver metastases (CLM) develop recurrence or tumor-related death. Therefore 10-year survival appears more adequate in defining permanent cure. The aim of this study was to develop prognostic models for the prediction of 10-year survival after liver resection for colorectal liver metastases. Read More

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October 2018
5 Reads

Recurrence of Hepatitis B Infection in Liver Transplant Patients Receiving Long-Term Hepatitis B Immunoglobulin Prophylaxis.

Ann Transplant 2018 Nov 13;23:789-801. Epub 2018 Nov 13.

Transplant Centre, Faculty of Medicine, Azienda Ospedaliera Policlinico Tor Vergata, Rome, Italy.

BACKGROUND Long-term real-world data are relatively sparse regarding recurrence of chronic hepatitis B virus (HBV) infection after liver transplantation using hepatitis B immunoglobulin (HBIg) and nucleos(t)ide analogue (NUC) prophylaxis. MATERIAL AND METHODS Data from 371 adults transplanted for HBV-related disease at 20 European centers and given HBIg for ³12 months ± NUC therapy were analyzed retrospectively. RESULTS HBIg comprised Hepatect® (iv HBIgB; n=299), subcutaneous Zutectra® (sc HBIg, n=236), and other HBIg preparations (n=130); 93. Read More

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November 2018
10 Reads

Transthoracic cholecystectomy following biliary pancreatitis arising from a thoracic herniated gallbladder.

J Visc Surg 2018 Dec 9;155(6):513-515. Epub 2018 Nov 9.

Department of HPB Surgery and Liver Transplant, Beaujon Hospital, Clichy, Université Paris VII Diderot, Assistance Publique-Hôpitaux de Paris, 100, boulevard du Général Leclerc, 92110 Clichy, Paris, France.

Asymptomatic right diaphragmatic rupture with liver and gallbladder herniation and secondary Budd-Chiari syndrome is a rare complication of abdominal trauma. In this setting, the management of gallbladder stones remains poorly described and may require a thoracic approach. Read More

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December 2018
4 Reads

Impact of Donor Hepatectomy Time during Organ Procurement in Donation after Circulatory Death Liver Transplantation: The United Kingdom Experience.

Transplantation 2018 Nov 9. Epub 2018 Nov 9.

Department of HPB and Transplantation, St James University Hospital, Beckett Street, Leeds, United Kingdom, LS9 7TF.

Background: No data exists to evaluate how hepatectomy time (HT), in the context of donation after cardiac death (DCD) procurement, impacts on short and long-term outcomes following liver transplantation (LT). In this study we analyse the impact of the time from aortic perfusion to end of hepatectomy on outcomes following DCD LT in the UK.

Methods: An analysis of 1112 DCD donor LT across all UK transplant centres between 2001 and 2015 was performed, using data from the UK Transplant Registry. Read More

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November 2018

Extended laparoscopic distal pancreatectomy for adenocarcinoma in the body and tail of the pancreas: a single-center experience.

Langenbecks Arch Surg 2018 Nov 11. Epub 2018 Nov 11.

The Intervention Center, Oslo University Hospital, Rikshospitalet, 0027, Oslo, Norway.

Purpose: Extended resection is required for pancreatic adenocarcinoma infiltrating adjacent organs and structures. The role of laparoscopy in this setting is unclear. In this study, the outcomes of extended laparoscopic distal pancreatectomy (ELDP) for pancreatic body/tail adenocarcinoma were examined. Read More

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November 2018
2 Reads

Typing of pancreatic cancer-associated fibroblasts identifies different subpopulations.

World J Gastroenterol 2018 Nov;24(41):4663-4678

Department of Pathology, Odense University Hospital, Department of Clinical Research, University of Southern Denmark, Odense Pancreas Center (OPAC), Odense C 5000, Denmark.

Aim: To determine whether it is possible to identify different immune phenotypic subpopulations of cancer-associated fibroblasts (CAFs) in pancreatic cancer (PC).

Methods: We defined four different stromal compartments in surgical specimens with PC: The juxtatumoural, peripheral, lobular and septal stroma. Tissue microarrays were produced containing all pre-defined PC compartments, and the expression of 37 fibroblast (FB) and 8 extracellular matrix (ECM) markers was evaluated by immunohistochemistry, immunofluorescence (IF), double-IF, and/or hybridization. Read More

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November 2018
1 Read

Five year experience of gallbladder polyp surveillance and cost effective analysis against new European consensus guidelines.

HPB (Oxford) 2018 Nov 8. Epub 2018 Nov 8.

Hepatopancreatobiliary Unit, Addenbrooke's Hospital, Hills Road, Cambridge, CB2 0QQ, United Kingdom.

Background: Gallbladder polyp (GBP) surveillance seeks to identify early neoplasms, but practice varies amongst surgical units. Recent European consensus guidelines have recommended an evidence-based GBP surveillance strategy. In a tertiary centre Hepato-Pancreato-Biliary unit we examine GBP surveillance, malignant yield, and assess cost-effectiveness of the new European consensus guidelines. Read More

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November 2018
1 Read

Training for Minimally Invasive Cancer Surgery.

Surg Oncol Clin N Am 2019 Jan 23;28(1):11-30. Epub 2018 Oct 23.

Virginia Mason Medical Center, 1100 Ninth Avenue, GS-C6, Seattle, WA 98101, USA; HPB and Endocrine Surgery, Virginia Mason Medical Center, 1100 Ninth Avenue, GS-C6, Seattle, WA 98101, USA.

The surgical oncologist of the future requires training in minimally invasive techniques. Increasing constraints on time and resources have led to a new emphasis on finding innovative ways to teach these surgical skills inside and outside the operating room. The goal of producing technically gifted minimally invasive surgical (MIS) oncologists requires robust, educationally sound training curricula. Read More

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January 2019
1 Read
1.674 Impact Factor

Emergency presentations of acute biliary pain: changing patterns of management in a tertiary institute.

ANZ J Surg 2018 Dec 9;88(12):1337-1342. Epub 2018 Nov 9.

HPB and Transplant Unit, Austin Hospital, Melbourne, Victoria, Australia.

Background: Acute biliary pain is the most common presentation of gallstone disease. Untreated patients risk recurrent pain, cholecystitis, obstructive jaundice, pancreatitis and multiple hospital presentations. We examine the outcome of implementing a policy to offer laparoscopic cholecystectomy on index presentation to patients with biliary colic in a tertiary hospital in Australia. Read More

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December 2018
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