4,995 results match your criteria HPB : the official journal of the International Hepato Pancreato Biliary Association[Journal]


Outcomes of different surgical resection techniques for end-stage hepatic alveolar echinococcosis with inferior vena cava invasion.

HPB (Oxford) 2019 Feb 16. Epub 2019 Feb 16.

Department of Liver Surgery, Liver Transplantation Center, West China Hospital of Sichuan University, Chengdu, Sichuan Province, China. Electronic address:

Background: Hepatic alveolar echinococcosis (HAE) lesions with inferior vena cava (IVC) invasion require combined resection of the liver and IVC. The outcomes of different surgical treatments, including in situ, ante situm and ex vivo resection, remain unclear.

Methods: A total of 71 consecutive HAE patients who underwent hepatectomy with retrohepatic IVC resection were included. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.hpb.2018.10.023DOI Listing
February 2019

Pasireotide for the prevention of postoperative pancreatic fistula: an open debate.

HPB (Oxford) 2019 Feb 16. Epub 2019 Feb 16.

Surgical Oncology Unit, Azienda Unità Sanitaria Locale/IRCCS di Reggio Emilia, Arcispedale Santa Maria Nuova di Reggio Emilia, Viale Risorgimento, 80, 42123, Reggio Emilia, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.hpb.2019.01.010DOI Listing
February 2019

Diaphragmatic injury during laparoscopic cholecystectomy: An unusual complication during a routine case.

J Minim Access Surg 2019 Feb 18. Epub 2019 Feb 18.

Department of Surgical Gastroenterology, Institute of Digestive and HPB Sciences, Sakra World Hospital, Bengaluru, Karnataka, India.

Laparoscopic cholecystectomy is one of the most common procedures performed in surgical practice worldwide. Diaphragmatic injury is an extremely rare complication that can occur intraoperatively and needs to be dealt with immediately. This article describes a case report of diaphragmatic injury, technical details of how to deal with this complication and preventive strategies along with a review of literature on the topic. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4103/jmas.JMAS_315_18DOI Listing
February 2019

What should be known prior to performing EUS?

Endosc Ultrasound 2019 Jan-Feb;8(1):3-16

Department of Internal Medicine, Krankenhaus Maerkisch-Oderland, D-15344 Strausberg and Brandenburg Institute of Clinical Ultrasound at Medical University Brandenburg, Germany.

Direct referral of patients for EUS - instead of preprocedural consultation with the endosonographer - has become standard practice (like for other endoscopic procedures) as it is time- and cost-effective. To ensure appropriate indications and safe examinations, the endosonographer should carefully consider what information is needed before accepting the referral. This includes important clinical data regarding relevant comorbidities, the fitness of the patient to consent and undergo the procedure, and the anticoagulation status. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4103/eus.eus_54_18DOI Listing
February 2019

Surgical management of the grade C pancreatic fistula after pancreatoduodenectomy.

HPB (Oxford) 2019 Feb 15. Epub 2019 Feb 15.

Department of General, Gastroenterological and Oncological Surgery, Medical University of Warsaw, ul. Banacha 1A, 02-097, Warsaw, Poland.

Background: Surgical management of severe pancreatic fistula after pancreatoduodenectomy remains challenging, and carries high mortality. The aim of this retrospective study was to compare different surgical techniques used at relaparotomy for pancreatic fistula after pancreatoduodenectomy, and to identify factors predictive of failure to rescue.

Methods: A total of 43 patients after pancreatoduodenectomy developed a pancreatic fistula requiring relaparotomy. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.hpb.2019.01.006DOI Listing
February 2019

Cholecystectomy for gallstone pancreatitis should never be difficult.

HPB (Oxford) 2019 Feb 15. Epub 2019 Feb 15.

The University of Manchester, Manchester Academic Health Science Centre, Lancashire Teaching Hospital NHS Foundation Trust and the University of Central Lancashire, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.hpb.2019.01.013DOI Listing
February 2019

Isolated pulmonary recurrence after resection of pancreatic cancer: the effect of patient factors and treatment modalities on survival.

HPB (Oxford) 2019 Feb 15. Epub 2019 Feb 15.

Department of Surgery, The Sol Goldman Pancreatic Cancer Research Center, The Johns Hopkins University School of Medicine, Baltimore, MD, USA. Electronic address:

Background: The literature suggests favorable survival for patients with isolated pulmonary recurrence after resection of pancreatic ductal adenocarcinoma (PDAC) as compared to other recurrence patterns. Within this cohort, it remains unclear what factors are associated with improved survival.

Methods: Patients who developed pulmonary recurrence after pancreatectomy were selected from a prospective database. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.hpb.2018.12.002DOI Listing
February 2019

Factors predicting ablation site recurrence following percutaneous microwave ablation of colorectal hepatic metastases.

HPB (Oxford) 2019 Feb 16. Epub 2019 Feb 16.

Department of HPB Surgery, Churchill Hospital, Oxford University Hospitals NHS Foundation Trust.

Background: Microwave ablation (MWA) is a recognised treatment option for liver metastases. The size of the tumour is a well-established factor that influences the success of MWA. However, the effect of "heat sink" on the success of MWA for hepatic metastases is unclear. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.hpb.2019.01.007DOI Listing
February 2019

Can hypothermic oxygenated perfusion (HOPE) rescue futile DCD liver grafts?

HPB (Oxford) 2019 Feb 15. Epub 2019 Feb 15.

Department of Surgery and Transplantation, Swiss HPB Centre, University Hospital Zurich, Zurich, Switzerland. Electronic address:

Background: The new UK-DCD-Risk-Score has been recently developed to predict graft loss in DCD liver transplantation. Donor-recipient combinations with a cumulative risk of >10 points were classified as futile and achieved an impaired one-year graft survival of <40%. The aim of this study was to show, if hypothermic oxygenated perfusion (HOPE) can rescue such extended DCD livers and improve outcomes. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.hpb.2019.01.004DOI Listing
February 2019

The impact of posthepatectomy liver failure on long-term survival after hepatectomy for colorectal liver metastasis.

HPB (Oxford) 2019 Feb 15. Epub 2019 Feb 15.

Division of Hepato-Biliary-Pancreatic Surgery, Shizuoka Cancer Center Hospital, Shizuoka, Japan.

Background: Postoperative complications affect both the short-term and long-term outcomes. The aim of this study was to identify specific prognostic factors among complications after hepatectomy for colorectal liver metastasis (CRLM).

Methods: Between 2002 and 2014, 427 patients underwent initial hepatectomy for CRLM. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.hpb.2019.01.008DOI Listing
February 2019

Enteral versus parenteral nutrition following pancreaticoduodenectomy: a systematic review and meta-analysis.

HPB (Oxford) 2019 Feb 14. Epub 2019 Feb 14.

Department of Hepatobiliary Surgery, Nottingham Digestive Diseases Centre and National Institute for Health Research (NIHR), Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust and University of Nottingham, Queen's Medical Centre, Nottingham, NG7 2UH, United Kingdom. Electronic address:

Background: The need for nutritional support following pancreaticoduodenectomy is well recognised due to the high prevalence of malnutrition, but the optimal delivery route is still debated. This meta-analysis evaluated postoperative outcomes in patients receiving enteral or parenteral nutrition.

Methods: EMBASE, MEDLINE and Cochrane databases were searched to identify randomised controlled trials comparing enteral and parenteral nutrition in patients undergoing pancreaticoduodenectomy. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.hpb.2019.01.005DOI Listing
February 2019

Effect of pharmacological preconditioning with sevoflurane during hepatectomy with intermittent portal triad clamping.

HPB (Oxford) 2019 Feb 15. Epub 2019 Feb 15.

Anesthésie-Réanimation, Hôpital Huriez CHRU Lille, France.

Background: During hepatectomy, intermittent portal triad clamping (IPC) reduces ischemia-reperfusion injuries. Pharmacological preconditioning with sevoflurane revealed similar properties. The aim of the study was to evaluate the combination of a sevoflurane preconditioning regimen with IPC on ischemia-reperfusion injuries. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S1365182X193006
Publisher Site
http://dx.doi.org/10.1016/j.hpb.2019.01.009DOI Listing
February 2019
1 Read

Biological and conditional factors should be included when defining criteria for resectability for patients with pancreatic cancer.

HPB (Oxford) 2019 Feb 14. Epub 2019 Feb 14.

Department of Gastroenterological Surgery (Surgery II), Nagoya University Graduate School of Medicine, Nagoya, Japan.

Background: This study aimed to evaluate novel resectability criteria for pancreatic ductal adenocarcinoma (PDAC) proposed by the International Association of Pancreatology (IAP) by comparing them with the National Comprehensive Cancer Network (NCCN) guidelines.

Methods: 369 patients who underwent upfront surgery for PDAC were retrospectively analyzed. Overall survival (OS) of each group as defined by either of the guidelines were compared and preoperative prognostic factors for OS were identified. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.hpb.2019.01.012DOI Listing
February 2019
1 Read

Cholecystectomy During the Third Trimester of Pregnancy: Proceed or Delay?

J Am Coll Surg 2019 Jan 8. Epub 2019 Jan 8.

Department of Surgery, Massachusetts General Hospital, Boston, MA.

Background: Current guidelines suggest that cholecystectomy during the third trimester of pregnancy is safe for both the women and the fetus. However, no population-based study has examined this issue. The aim of this analysis was to compare the results of cholecystectomy during the third trimester of pregnancy with outcomes in women operated on in the early postpartum period in a large population. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S10727515193002
Publisher Site
http://dx.doi.org/10.1016/j.jamcollsurg.2018.12.024DOI Listing
January 2019
1 Read

Malnutrition associated with an increased risk of postoperative complications following hepatectomy in patients with hepatocellular carcinoma.

HPB (Oxford) 2019 Feb 11. Epub 2019 Feb 11.

Department of Nutrition, Chang Gung Memorial Hospital, Chiayi, 613, Taiwan.

Background: The aim of this study was to analyze the nutritional risk factors for postoperative complications following hepatic resection for hepatocellular carcinoma (HCC).

Methods: The preoperative nutritional status of patients with HCC who underwent hepatic resection was evaluated using the scored Patient-Generated Subjective Global Assessment (PG-SGA). The perioperative variables were compared between well-nourished and malnourished patients. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.hpb.2019.01.003DOI Listing
February 2019

Long term outcomes of patients transplanted for hepatocellular carcinoma with human immunodeficiency virus infection.

HPB (Oxford) 2019 Feb 11. Epub 2019 Feb 11.

Department of Surgery - Transplant Division, University of Kentucky, College of Medicine, Lexington, KY, USA. Electronic address:

Background: We aimed to study outcomes in HIV + patients with HCC in the US following Liver Transplantation (LT) using the UNOS dataset.

Methods: The database was queried from 2003 to 2016 for patients undergoing LT with HCC, HIV+, and HCC/HIV+.

Results: Out of 17,397 LT performed for HCC during the study period, 113 were transplanted for HCC with HIV infection (91 isolated livers). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.hpb.2019.01.001DOI Listing
February 2019

Characterization of early recurrences following liver resection by ALPPS and two stage hepatectomy in patients with colorectal liver-metastases and small future liver remnants; a translational substudy of the LIGRO-RCT.

HPB (Oxford) 2019 Feb 11. Epub 2019 Feb 11.

Department of Surgery and Clinical and Experimental Medicine, Linköping University, Linköping, Sweden.

Background: Associated liver partition and portal vein ligation in staged hepatectomy (ALPPS) is an alternative resection method to portal vein embolization (PVE) in patients with small future liver remnants (FLR) but has been associated with early tumor recurrences.

Methods: Twenty-four patients with colorectal liver metastases (CRLM) patients from the randomized multicenter LIGRO trial comparing outcome of ALPPS (n = 13) vs PVE (n = 11) were included in the study. Mutational analyses of the KRAS, NRAS, BRAF, PIC3CA and TP53 genes of the metastases were performed in 21 patients and correlated to early tumor recurrence. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.hpb.2018.12.003DOI Listing
February 2019

MRI texture analysis for differentiation of malignant and benign hepatocellular tumors in the non-cirrhotic liver.

Heliyon 2018 Nov 30;4(11):e00987. Epub 2018 Nov 30.

Institute of Interventional and Diagnostic Radiology, University Hospital Zurich and University of Zurich, Zurich, Switzerland.

Purpose: To find potentially diagnostic texture analysis (TA) features and to evaluate the diagnostic accuracy of two-dimensional (2D) magnetic resonance (MR) TA for differentiation between hepatocellular carcinoma (HCC) and benign hepatocellular tumors in the non-cirrhotic liver in an exploratory MR-study.

Materials And Methods: 108 non-cirrhotic patients (62 female; 41.5 ± 18. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.heliyon.2018.e00987DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286882PMC
November 2018

Hypothermic Oxygenated Perfusion (HOPE) - A simple and effective method to modulate the immune response in kidney transplantation.

Transplantation 2019 Feb 4. Epub 2019 Feb 4.

Department of Surgery and Transplantation, Swiss HPB Centre, University Hospital Zurich, Switzerland.

Background: Hypothermic oxygenated perfusion (HOPE) has been shown to protect liver recipients from acute rejection in an allogeneic model of liver transplantation in rats. Here we investigate the impact of HOPE on the T-Cell mediated immune response following kidney transplantation.

Methods: Kidneys from Lewis rats were transplanted into Brown Norway recipients to trigger acute rejection (allogeneic untreated group). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/TP.0000000000002634DOI Listing
February 2019

Yes-associated protein promotes early hepatocyte cell cycle progression in regenerating liver after tissue loss.

FASEB Bioadv 2019 Jan 27;1(1):51-61. Epub 2018 Nov 27.

Laboratory of the Swiss HPB and Transplantation Center, Department of Surgery University Hospital Zürich Zürich Switzerland.

The ability of the liver to restore its original volume following tissue loss has been associated with the Hippo-YAP1 pathway, a key controller of organ size. Yes-associated protein 1 (YAP1)-a growth effector usually restrained by Hippo signaling-is believed to be of particular importance; however, its role in liver regeneration remains ill-defined. To explore its function, we knocked down YAP1 prior to standard 70%-hepatectomy (sHx) using a hepatocyte-specific nanoformulation. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1096/fba.1023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351850PMC
January 2019
1 Read

The issue of how predict survival of patients affected by locally advanced pancreatic cancer.

Authors:
Benedetto Ielpo

Ann Transl Med 2018 Dec;6(Suppl 2):S128

HPB Unit, General Surgery, University Hospital of Leon, Calle Altos de Nava s/n León, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21037/atm.2018.12.41DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330600PMC
December 2018

Pancreatic fistula following laparoscopic distal pancreatectomy is probably unrelated to the stapler size but to the drainage modality and significantly decreased with a small suction drain.

Langenbecks Arch Surg 2019 Feb 9. Epub 2019 Feb 9.

Department of HPB surgery and liver transplantation, Beaujon Hospital, APHP, University Paris VII, 100 boulevard du General Leclerc, 92110, Clichy, France.

Introduction: Risk factors of postoperative pancreatic fistula (POPF) after laparoscopic distal pancreatectomy (LDP) are not well known and were studied, including the stapler cartridge size and drainage modality.

Methods: Between January 2008 and December 2016, 181 LDP were performed and the pancreas was sectioned by stapler in 130 patients (72%). Patients received white (2. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00423-019-01756-3DOI Listing
February 2019

Outcomes following percutaneous treatment of biliary stones.

HPB (Oxford) 2019 Feb 6. Epub 2019 Feb 6.

Radiology Unit, Department of Diagnostic and Preventive Medicine, S. Orsola-Malpighi University Hospital, Bologna, Italy.

Background: The percutaneous approach (PA) for management of biliary stones (BS) with or without an underlying biliary stenosis is an option for patients in whom an endoscopic approach (EA) is not possible. The aim of this study was to evaluate the efficacy of a PA in patients with BS unsuitable for an EA.

Methods: A retrospective review of a database was performed. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.hpb.2018.12.007DOI Listing
February 2019

A prospective, multi-institution assessment of irreversible electroporation for treatment of locally advanced pancreatic adenocarcinoma: initial outcomes from the AHPBA pancreatic registry.

HPB (Oxford) 2019 Feb 5. Epub 2019 Feb 5.

University of Louisville, Hiram C. Polk Jr, MD Department of Surgery, Division of Surgical Oncology, Louisville, KY, USA. Electronic address:

Background: The optimal treatment and management of locally advanced pancreatic cancer (LAPC) remains unclear and controversial. This study aimed to report the initial outcomes of the AHPBA Registry and evaluate the reproducibility of existing evidence that the addition of Irreversible Electroporation (IRE), a nonthermal ablative treatment, confers survival benefits beyond standard therapeutic options for patients with LAPC.

Methods: From December 2015 to October 2017, patients with LAPC were treated with open-technique IRE following the AHPBA Registry Protocols. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.hpb.2018.12.004DOI Listing
February 2019

Selective Indication of T-Tube in Liver Transplantation: Prospective Validation of the Results of a Randomized Controlled Trial.

Transplant Proc 2019 Jan - Feb;51(1):44-49. Epub 2018 Jun 28.

HPB Surgery and Transplant Unit, La Fe University Hospital, Valencia, Spain.

Background And Aims: T-tube placement during choledochocholedochostomy (CCS) associated with liver transplantation (LT) remains controversial. This study was designed to validate the results of an earlier prospective randomized controlled trial (RCT) on use versus nonuse of the T-tube during CCS associated with LT.

Methods: Prospective cohort study. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.transproceed.2018.03.133DOI Listing

Retroelement-Linked Transcription Factor Binding Patterns Point to Quickly Developing Molecular Pathways in Human Evolution.

Cells 2019 Feb 6;8(2). Epub 2019 Feb 6.

I.M. Sechenov First Moscow State Medical University, Moscow 119991, Russia.

Background: Retroelements (REs) are transposable elements occupying ~40% of the human genome that can regulate genes by providing transcription factor binding sites (TFBS). RE-linked TFBS profile can serve as a marker of gene transcriptional regulation evolution. This approach allows for interrogating the regulatory evolution of organisms with RE-rich genomes. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/cells8020130DOI Listing
February 2019
2 Reads

Radioembolisation with 90Y microspheres for neuroendocrine liver metastases: an institutional case series, systematic review and meta-analysis.

HPB (Oxford) 2019 Feb 4. Epub 2019 Feb 4.

Department of Imaging, Imperial College London, Hammersmith Hospital, London, W12 0HS, United Kingdom.

Background: Neuroendocrine liver metastases are clinically challenging due to their frequent disseminated distribution. This study aims to present a British experience with an emerging modality, radioembolisation with yttrium-90 labelled microspheres, and embed this within a meta-analysis of response and survival outcomes.

Methods: A retrospective case series of patients treated with SIR-Spheres (radiolabelled resin microspheres) was performed. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.hpb.2018.12.014DOI Listing
February 2019

The predictive value of future liver remnant function after liver resection for HCC in noncirrhotic and cirrhotic patients.

HPB (Oxford) 2019 Feb 4. Epub 2019 Feb 4.

Department of Surgery, Campus Virchow-Klinikum and Campus Charité Mitte, Charité - Universitätsmedizin Berlin, Augustenburger Platz 1, 13353, Berlin, Germany; Department of General, Visceral, Vascular and Pediatric Surgery, Universitätsklinikum des Saarlandes, Kirrberger Straße, 66421 Homburg, Germany. Electronic address:

Background: Surgical procedures in patients with underlying liver disease are still burdened by a high rate of postoperative morbidity, especially posthepatectomy liver failure (PHLF), ranging from 1.2 to 33.8%. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.hpb.2018.11.012DOI Listing
February 2019

CD11bLy6G myeloid-derived suppressor cells promote liver regeneration in a murine model of major hepatectomy.

FASEB J 2019 Feb 7:fj201801733R. Epub 2019 Feb 7.

The Surgical Division, Department of Surgery B, The Laboratory of Molecular Genetics, Hepato-Pancreato-Biliary (HPB) Cancer Research, Tel-Aviv Sourasky Medical Center-The Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel.

Liver regeneration depends on sequential activation of pathways and cells involving the remaining organ in recovery of mass. Proliferation of parenchyma is dependent on angiogenesis. Understanding liver regeneration-associated neovascularization may be useful for development of clinical interventions. Read More

View Article

Download full-text PDF

Source
https://www.fasebj.org/doi/10.1096/fj.201801733R
Publisher Site
http://dx.doi.org/10.1096/fj.201801733RDOI Listing
February 2019
1 Read

Detection of visually occult metastatic lymph nodes using molecularly targeted fluorescent imaging during surgical resection of pancreatic cancer.

HPB (Oxford) 2019 Feb 2. Epub 2019 Feb 2.

Department of Surgery, Stanford University, Stanford, CA, USA. Electronic address:

Background: Although most patients with PDAC experience distant failure after resection, a significant portion still present with local recurrence. Intraoperative fluorescent imaging can potentially facilitate the visualization of involved peritumoral LNs and guide the locoregional extent of nodal dissection. Here, the efficacy of targeted intraoperative fluorescent imaging was examined in the detection of metastatic lymph nodes (LNs) during resection of pancreatic ductal adenocarcinoma (PDAC). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.hpb.2018.11.008DOI Listing
February 2019

Complex liver resection under hepatic vascular exclusion and hypothermic perfusion with versus without veno-venous bypass: a comparative study.

HPB (Oxford) 2019 Feb 2. Epub 2019 Feb 2.

Department of Hepato-Pancreatico-Biliary Surgery and Liver Transplant, Hôpital Beaujon, Assistance Publique-Hôpitaux de Paris, 100 Boulevard du Général Leclerc, 92110, Clichy, France(4). Electronic address:

Background: While hypothermic liver perfusion has been shown to improve parenchymal tolerance to complex resections in patients requiring prolonged hepatic vascular exclusion (HVE), the benefit of associated veno-venous bypass (VVB) in this setting remains poorly evaluated.

Methods: All patients undergoing liver resection requiring HVE and hypothermic liver perfusion for at least 55 min between 2006 and 2017 were retrospectively reviewed. Perioperative outcomes were compared between patients with (VVB+) or without VVB (VVB-). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.hpb.2018.12.012DOI Listing
February 2019
1 Read

Transversus abdominis plane block reduces pain and narcotic consumption after robot-assisted distal pancreatectomy.

HPB (Oxford) 2019 Feb 2. Epub 2019 Feb 2.

Pancreas and Liver Institute, Beth Israel Deaconess Medical Center, Boston, MA, USA. Electronic address:

Background: Minimizing pain and disability are key postoperative objectives of robot-assisted distal pancreatectomy (RADP). This study tested effects of bupivacaine transversus abdominis plane (TAP) block on opioid consumption and pain after RADP.

Methods: Retrospective case-control study (June 2012 -Oct 2017) evaluating bilateral intraoperative bupivacaine TAP block as an interrupted time series. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.hpb.2018.12.005DOI Listing
February 2019

Use of perioperative epidural analgesia among Medicare patients undergoing hepatic and pancreatic surgery.

HPB (Oxford) 2019 Feb 2. Epub 2019 Feb 2.

Division of Surgical Oncology, The Ohio State University Wexner Medical Center and James Comprehensive Cancer Center, Columbus, OH, USA. Electronic address:

Background: We sought to characterize epidural analgesia (EA) use among Medicare patients undergoing hepatopancreatic (HP) procedures, identify factors associated with EA use and asses perioperative outcomes.

Methods: Patients undergoing HP surgery were identified using the Inpatient Standard Analytic Files. Logistic regression was utilized to identify factors associated with EA receipt, and assess associations of EA with in-hospital outcomes and Medicare expenditures. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.hpb.2018.12.008DOI Listing
February 2019

Complications after liver surgery: a benchmark analysis.

HPB (Oxford) 2019 Feb 1. Epub 2019 Feb 1.

Department of Surgery, The Ohio State University Wexner Medical Center, Columbus, OH, USA. Electronic address:

Background: The best achievable short-term outcomes after liver surgery have not been identified. Several factors may influence the post-operative course of patients undergoing hepatectomy increasing the risk of post-operative complications. We sought to identify risk-adjusted benchmark values [BMV] for liver surgery. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.hpb.2018.12.013DOI Listing
February 2019

Impact of concomitant ablation on the perioperative outcomes of patients with colorectal liver metastases undergoing hepatectomy: a propensity score matched nationwide analysis.

HPB (Oxford) 2019 Feb 1. Epub 2019 Feb 1.

Department of Surgery, Wexner Medical Center at the Ohio State University, Columbus, OH, USA. Electronic address:

Background: Intraoperative ablation (IA) is often performed at the time of liver resection (LR) for colorectal liver metastases (CRLMs) but its impact on postoperative outcomes remains poorly understood.

Methods: The ACS-NSQIP targeted hepatectomy database was used to identify patients who underwent LR vs LR + IA for CRLMs during 2014-2016. Perioperative outcomes were compared following propensity score match based on age, receipt of neoadjuvant therapy, operative approach, liver resection type, tumor diameter and number of metastases. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.hpb.2018.12.010DOI Listing
February 2019

The impact of resection margin and microvascular invasion on long-term prognosis after curative resection of hepatocellular carcinoma: a multi-institutional study.

HPB (Oxford) 2019 Feb 1. Epub 2019 Feb 1.

Department of Hepatobiliary Surgery, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, China. Electronic address:

Background: The resection margin (RM) status and microscopic vascular invasion (MVI) are known prognostic factors for hepatocellular carcinoma (HCC). An enhanced understanding of their impact on long-term prognosis is required to improve oncological outcomes.

Methods: Using multi-institutional data, the different impact of the RM status (narrow, <1 cm, or wide, ≥1 cm) and MVI (positive or negative) on overall survival (OS) and recurrence-free survival (RFS) after curative liver resection of solitary HCC without macrovascular invasion was analyzed. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.hpb.2018.11.005DOI Listing
February 2019

Recipient body mass index and infectious complications following liver transplantation.

HPB (Oxford) 2019 Jan 31. Epub 2019 Jan 31.

Department of Hepato-Pancreato-Biliary Surgery & Liver Transplantation, Royal Free Hospital, Pond Street, Hampstead, NW3 2QG, London, UK.

Background: Nutritional problems are common in patients requiring liver transplantation. Recipient obesity or malnutrition are thought to increase postoperative complications. Body mass index (BMI) is commonly used prior to major surgery but its value specifically in liver transplant assessment has not been established. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.hpb.2019.01.002DOI Listing
January 2019

Expanded Makuuchi's criteria using estimated indocyanine green clearance rate of future liver remnant as a safety limit for maximum extent of liver resection.

HPB (Oxford) 2019 Jan 30. Epub 2019 Jan 30.

Hepato-Biliary-Pancreatic Surgery Division, Department of Gastroenterological Surgery, Toranomon Hospital, Japan; Okinaka Memorial Institute for Medical Disease, Tokyo, Japan. Electronic address:

Background: Recent advances in liver surgery have dramatically improved the safety of hepatectomy for hepatocellular carcinoma (HCC). The aim of this study was to compare outcomes for patients fulfilling an extended criteria vs. those fulfilling the conventional criteria based on the bilirubin and indocyanine green (ICG) clearance (Makuuchi's criteria). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.hpb.2018.12.001DOI Listing
January 2019

Incidental versus non-incidental gallbladder cancer: index cholecystectomy before oncologic re-resection negatively impacts survival in T2b tumors.

HPB (Oxford) 2019 Jan 30. Epub 2019 Jan 30.

Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. Electronic address:

Background: Conflicting data exists whether non-oncologic index cholecystectomy (IC) leading to discovery of incidental gallbladder cancer (IGBC) negatively impacts survival. This study aimed to determine whether a subgroup of patients derives a disadvantage from IC.

Methods: Patients with IGBC and non-IGBC treated at an academic USA and Chilean center during 1999-2016 were compared. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.hpb.2018.12.006DOI Listing
January 2019
1 Read

Living donor liver transplantation in a patient with cocoon abdomen - Anesthesia concerns!

Saudi J Anaesth 2019 Jan-Mar;13(1):75-77

Department of HPB and Liver Transplantation, Institute of Liver and Biliary Sciences, New Delhi, India.

Cocoon abdomen is a rare condition in which abdominal structures are surrounded by thick encapsulating peritoneum resulting in dense adhesions. Liver transplant is a high risk surgery with an already increased risk of massive blood loss due to the pre-existing coagulopathy and portal hypertension. Presence of cocoon abdomen with severe dense adhesions can either lead to difficult hepatectomy with massive intra-operative blood loss or failure to proceed with the surgery. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4103/sja.SJA_655_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329246PMC
January 2019
1 Read

Systematic Review on Characteristics and Reporting Quality of Animal Studies in Liver Regeneration Triggered by Portal Vein Occlusion and Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy: Adherence to the ARRIVE Guidelines.

J Surg Res 2019 Mar 5;235:578-590. Epub 2018 Dec 5.

Institute for Laboratory Animal Science and Experimental Surgery, University Hospital RWTH Aachen, Aachen, Germany.

Background: Portal vein occlusion and associating liver partition and portal vein ligation for staged hepatectomy techniques are in the spotlight of oncological liver surgery. Research involving animal models is indispensable to study the mechanisms of liver regeneration. Inaccurate reporting acts as a significant barrier during the correct interpretation of preclinical findings. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00224804183076
Publisher Site
http://dx.doi.org/10.1016/j.jss.2018.10.038DOI Listing
March 2019
6 Reads

Recipient obesity does not affect survival after deceased donor liver transplantation for hepatocellular carcinoma. A national retrospective cohort study in the United States.

HPB (Oxford) 2019 Jan 7;21(1):67-76. Epub 2018 Jul 7.

Division of Transplant Surgery, University of Pittsburgh Medical Centre, Pittsburgh, PA, USA. Electronic address:

Background: The oncological effects of obesity on liver transplant (LT) patients with hepatocellular carcinoma (HCC) remains unclear. We investigated patient overall survival and tested two-way interactions between donor and recipient obesity status.

Methods: Using the UNOS database, a total of 8352 LT recipients with HCC were included. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.hpb.2018.06.1797DOI Listing
January 2019

DNA-Decorated, Helically Twisted Nanoribbon: A Scaffold for the Fabrication of One-Dimensional, Chiral, Plasmonic Nanostructures.

Angew Chem Int Ed Engl 2019 Jan 28. Epub 2019 Jan 28.

School of Chemistry, Indian Institute of Science Education and Research (IISER) Thiruvananthapuram, Trivandrum-, 695551, Kerala, India.

Crafting of chiral plasmonic nanostructures is extremely important and challenging. DNA-directed organization of nanoparticle on a chiral template is the most appealing strategy for this purpose. Herein, we report a supramolecular approach for the design of DNA-decorated, helically twisted nanoribbons through the amphiphilicity-driven self-assembly of a new class of amphiphiles derived from DNA and hexaphenylbenzene (HPB). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/anie.201813900DOI Listing
January 2019

Robotic intersphincteric resection with right seminal vesicle excision via a right vascular approach using the Da Vinci Xi robotic system - a video vignette.

Colorectal Dis 2019 Jan 27. Epub 2019 Jan 27.

Division of Gastrointestinal and HPB Surgery, Tata Memorial Centre, Mumbai, India.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/codi.14570DOI Listing
January 2019
2.351 Impact Factor

Reproducibility of the Peritoneal Regression Grading Score (PRGS) for assessment of response to therapy in peritoneal metastasis.

Histopathology 2019 Jan 27. Epub 2019 Jan 27.

Department of Pathology, Odense University Hospital, Odense, Denmark.

Introduction: The 4-tiered Peritoneal Regression Grading Score (PRGS) is assessing response to chemotherapy in peritoneal metastasis (PM). The PRGS is for example used to assess response to Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC). However, the reproducibility of the PRGS is currently unkown. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/his.13829DOI Listing
January 2019

Chronic helminth infection does not impair immune response to malaria transmission blocking vaccine Pfs230D1-EPA/Alhydrogel® in mice.

Vaccine 2019 Feb 23;37(8):1038-1045. Epub 2019 Jan 23.

Laboratory of Malaria Immunology and Vaccinology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, USA. Electronic address:

Introduction: Malaria transmission blocking vaccines (TBV) are innovative approaches that aim to induce immunity in humans against Plasmodium during mosquito stage, neutralizing the capacity of the infected vectors to transmit malaria. Pfs230D1-EPA/Alhydrogel®, a promising protein-protein conjugate malaria TBV, is currently being tested in human clinical trials in areas where P. falciparum malaria is coendemic with helminth parasites. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.vaccine.2019.01.027DOI Listing
February 2019
4 Reads
3.624 Impact Factor

Can we predict recurrence in WHO G1-G2 pancreatic neuroendocrine neoplasms? Results from a multi-institutional Spanish study.

Pancreatology 2019 Jan 19. Epub 2019 Jan 19.

Pathology Department, Complejo Hospitalario Universitario de Vigo, Spain.

Introduction: Pancreatic neuroendocrine neoplasms (PNEN) are rare tumours and well differentiated PNEN are associated with relatively indolent physiological behaviour. For this reason, only few studies have investigated those factors associated with recurrence in this group of patients. The aim of this study is to analyse whether it is possible to predict tumour recurrence in World Health Organization (WHO) 2017 G1-G2 PNEN patients. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pan.2019.01.007DOI Listing
January 2019

Determinants of Health-related Quality of Life Among Mothers of Children With Cerebral Palsy.

J Pediatr Nurs 2019 Jan - Feb;44:1-8. Epub 2018 Oct 11.

College of Nursing, University of Illinois at Chicago, Chicago, IL, USA.

Purpose: Caring for a child with cerebral palsy (CP) can impact both the physical and mental health of parents. However, determinants associated with health-related quality of life (HRQOL) in these parents have yet to be adequately examined. The study aims were to identify the determinants affecting HRQOL among mothers of children with CP. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pedn.2018.10.001DOI Listing
October 2018
1 Read

Biomonitoring chronic lead exposure among battery manufacturing workers in Tunisia.

Environ Sci Pollut Res Int 2019 Jan 25. Epub 2019 Jan 25.

Laboratoire de Toxicologie et Environnement (LR12SP07), Centre d'Assistance Médicale et Urgente, 10 Rue Abou Kacem Chebbi, 1089, Montfleury, Tunis, Tunisia.

The aim of the study was the biomonitoring of the chronic exposure to Pb by measuring its levels in blood, urine, and hair of battery workers. Blood lead (BPb), urinary lead (UPb), hair lead (HPb), and urinary δ-aminolevulinic acid (UALA) levels were determined for 52 workers in a battery plant and compared to those of 20 non-occupational exposed subjects (controls). BPb and UPb levels were determined by graphite furnace atomic absorption spectrometry (GFAAS). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11356-019-04209-yDOI Listing
January 2019