Neuropsychol Rev 2009 Jun 9;19(2):169-85. Epub 2009 May 9.
Brain Sciences, University of New South Wales, and Department of Neurology, Xavier Building, Level 4, St. Vincent's Hospital, 390 Victoria Street, Sydney, NSW, 2010, Australia.
This article presents a review of studies that have investigated the neuropsychological effects of antiretroviral treatment (ART) for HIV-1 infection. It provides a brief overview of the era of monotherapy, dual-therapy, and an extended overview of the current era of combination antiretroviral therapy (CART). This review highlights that while CART has had a dramatic effect on the incidence and the severity of HIV-associated neurocognitive disorders (HAND), HAND, in its mild form, still remains prevalent. Read More