354 results match your criteria Gynecologic Needle Biopsy


Fine-needle aspiration cytology and core-needle biopsy in the diagnosis of lymphadenopathies: words of endorsement.

Eur J Haematol 2021 May 7. Epub 2021 May 7.

Department of Medicine and Surgery, Università degli Studi di Salerno, Italy.

we read with interest the letter to the Editor by Pizzi et al.: "Lymph node core needle biopsy for the diagnosis of lymphoproliferative disorders: a word of caution" which is a comment to an article by Cohen et al. Pizzi et al. Read More

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Ultrasound-Guided Omental Biopsy: Diagnostic Yield and Association with CT Features Based on a Single-Institution 18-Year Series.

AJR Am J Roentgenol 2021 Apr 14. Epub 2021 Apr 14.

Department of Radiology, University of Wisconsin School of Medicine and Public Health.

The greater omentum can serve as a useful target for percutaneous biopsy; in clinical practice, CT is commonly used for biopsy guidance. To evaluate the diagnostic yield of percutaneous ultrasound (US)-guided omental biopsy and to explore the association of diagnostic yield with pre-biopsy diagnostic CT findings. This retrospective study included 163 patients (mean age, 65±12 years; 120 women, 43 men; mean BMI, 28. Read More

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Assessing the value of second opinion pathology review.

Int J Qual Health Care 2021 Mar;33(1)

Department of Pathology, Medical College of Wisconsin, 9200 W. Wisconsin Avenue, Lab Building, Lower Level, Room L69, Milwaukee, WI 53226, USA.

Background: Second opinion review of pathology cases can identify diagnostic errors that impact patient care.

Objective: We sought out to determine discrepancy rates and clinical impact of review of pathology cases to reassess our policy of review on all second opinion cases.

Methods: All second opinion pathology cases over 1 year (2018) were retrospectively reviewed for discrepancy, multiple pathologist review and clinicopathologic features via chart and slide review. Read More

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Metastatic ovarian cancer spreading into mammary ducts mimicking an in situ component of primary breast cancer: a case report.

J Med Case Rep 2021 Feb 17;15(1):78. Epub 2021 Feb 17.

Division of Pathology, Cancer Institute of Japanese Foundation for Cancer Research, 3-8-31, Ariake, Koto-ku, Tokyo, 135-8550, Japan.

Background: Accurate diagnosis of metastatic tumors in the breast is crucial because the therapeutic approach is essentially different from primary tumors. A key morphological feature of metastatic tumors is their lack of an in situ carcinoma component. Here, we present a unique case of metastatic ovarian carcinoma spreading into mammary ducts and mimicked an in situ component of primary carcinoma. Read More

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February 2021

Surgical Technique for Sentinel Lymph Node Sampling in Presumed Early-stage Ovarian Cancer.

J Minim Invasive Gynecol 2020 Dec 30. Epub 2020 Dec 30.

Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Jewish General Hospital (all authors); Segal Cancer Center, Lady Davis Institute of Medical Research (Drs. Matanes, Kogan, Salvador, Gotlieb, and Lau), McGill University, Montreal, Quebec, Canada. Electronic address:

Study Objective: Surgical staging for apparent early-stage ovarian cancer includes systematic pelvic and para-aortic lymph node evaluation to detect occult stage III disease [1]. Although, lymphadenectomy procedure is associated with increased duration of surgery and a 13% risk of lymphocyst formation [2]. Sentinel lymph node (SLN) biopsy is still investigational, and no standardized approach has been studied. Read More

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December 2020

Breast Fine-Needle Aspiration Practice in 2019: Results of a College of American Pathologists National Survey.

Arch Pathol Lab Med 2020 Dec 22. Epub 2020 Dec 22.

The Department of Pathology, Ohio State University Medical Center, Columbus (Li).

Context.—: The College of American Pathologists surveys provide national benchmarks of pathology practice for laboratories.

Objective. Read More

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December 2020

Deep learning segmentation of general interventional tools in two-dimensional ultrasound images.

Med Phys 2020 Oct 30;47(10):4956-4970. Epub 2020 Aug 30.

Department of Medical Biophysics, Western University, London, Ontario, N6A 3K7, Canada.

Purpose: Many interventional procedures require the precise placement of needles or therapy applicators (tools) to correctly achieve planned targets for optimal diagnosis or treatment of cancer, typically leveraging the temporal resolution of ultrasound (US) to provide real-time feedback. Identifying tools in two-dimensional (2D) images can often be time-consuming with the precise position difficult to distinguish. We have developed and implemented a deep learning method to segment tools in 2D US images in near real-time for multiple anatomical sites, despite the widely varying appearances across interventional applications. Read More

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October 2020

Small Cell Carcinoma of Ovary, Hypercalcemic Type: Cytologic, Histopathologic, and Immunohistochemical Landscapes of a Rare Case.

J Pediatr Adolesc Gynecol 2021 Feb 1;34(1):98-102. Epub 2020 Aug 1.

Department of Histopathology, PGIMER, Chandigarh, India.

Background: Small cell carcinoma of ovary, hypercalcemia type (SCCOHT), also known as the malignant rhabdoid tumor of the ovary, is a rare and highly aggressive malignancy affecting younger women. The pathogenesis involves mutations in SWI/SNF-related, matrix-associated, actin-dependent regulator chromatin group A4 (SMARCA4)/Brahma-related gene 1 (BRG1) and/or SWI/SNF-related, matrix-associated, actin-dependent regulator chromatin group A2 (SMARCA2)/Brahma homolog (BRM).

Case: A 10-year-old girl presented with lower abdominal pain and a mass for the past 2 weeks. Read More

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February 2021

Two cases of spindle cell variant diffuse large B-cell lymphoma of the uterine cervix.

Gynecol Oncol Rep 2020 Aug 15;33:100611. Epub 2020 Jul 15.

Department of Gynecologic Oncology, Osaka International Cancer Institute, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-ku, Osaka 841-8567, Japan.

Lymphoma with prominent spindle cell features is a morphological variant of diffuse large B-cell lymphoma (DLBCL) and is categorized as a rare variant by the WHO classification. Most cases arise from the skin, with only two cases reported in the uterine cervix to date. Here, we report two cases of spindle cell variant DLBCL of the uterine cervix. Read More

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Solid Tumor Metastases to the Pancreas Diagnosed Using Fine-Needle Aspiration.

Am J Clin Pathol 2020 10;154(5):692-699

Department of Anatomical Pathology, Hepatology and Nutrition, University of Texas MD Anderson Cancer Center, Houston.

Objectives: Solid tumor metastases to the pancreas are rare, and only limited literature on the topic is available. In this retrospective study, we reviewed 107 cases of solid tumor metastases to the pancreas diagnosed by fine-needle aspiration (FNA) from 2005 to 2019.

Methods: Information including the patients' clinical histories, radiologic and pathologic findings, treatments, and follow-up were collected. Read More

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October 2020

A Proposal for the Performance, Classification, and Reporting of Lymph Node Fine-Needle Aspiration Cytopathology: The Sydney System.

Acta Cytol 2020 26;64(4):306-322. Epub 2020 May 26.

Department of Medicine and Surgery, Università degli Studi di Salerno, Fisciano, Salerno, Italy,

Background: The evaluation of lymph nodes (LN) by fine-needle aspiration cytology (FNAC) is routinely used in many institutions but it is not uniformly accepted mainly because of the lack of guidelines and a cytopathological diagnostic classification. A committee of cytopathologists has developed a system of performance, classification, and reporting for LN-FNAC.

Methods: The committee members prepared a document that has circulated among them five times; the final text has been approved by all the participants. Read More

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Primary cytoreductive surgery with or without hyperthermic intraperitoneal chemotherapy (HIPEC) for FIGO stage III epithelial ovarian cancer: OVHIPEC-2, a phase III randomized clinical trial.

Int J Gynecol Cancer 2020 06 23;30(6):888-892. Epub 2020 Mar 23.

Department of Gynaecology, Netherlands Cancer Institute, Amsterdam, The Netherlands

Background: The addition of hyperthermic intraperitoneal chemotherapy (HIPEC) to interval cytoreductive surgery improves recurrence-free and overall survival in patients with FIGO stage III ovarian cancer who are ineligible for primary cytoreductive surgery. The effect of HIPEC remains undetermined in patients who are candidates for primary cytoreductive surgery.

Primary Objective: The primary objective is to evaluate the effect of HIPEC on overall survival in patients with FIGO stage III epithelial ovarian cancer who are treated with primary cytoreductive surgery resulting in no residual disease, or residual disease up to 2. Read More

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Neuroendocrine carcinomas: Cytological mimics and diagnostic dilemmas.

Diagn Cytopathol 2020 May 24;48(5):440-445. Epub 2020 Jan 24.

Department of Cytology and Gynecologic Pathology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

Background: Neuroendocrine carcinomas (NEC) are rare tumours with multiple morphologic mimics. The cytologist may miss these cases if not aware.

Aims And Objects: We focused upon the clinical presentation, cytological features and problems in the diagnosis of NEC. Read More

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Lidocaine-Prilocaine Cream Compared With Injected Lidocaine for Vulvar Biopsy: A Randomized Controlled Trial.

Obstet Gynecol 2020 02;135(2):311-318

Department of Obstetrics and Gynecology, and Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Duke University Medical Center, and the Department of Biostatistics and Bioinformatics, Duke University School of Medicine, Durham, North Carolina.

Objective: To compare pain control during vulvar biopsy after either application of 5% lidocaine-prilocaine cream or injection of 1% lidocaine.

Methods: In a single-site randomized trial, patients who needed vulvar biopsy on a non-hair-bearing surface were recruited from a gynecologic oncology clinic to compare lidocaine-prilocaine cream (placed at least 10 minutes before biopsy) with lidocaine injection (at least 1 minute prior). A sample size of 53 participants in each arm (N=106) was planned. Read More

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February 2020

An interdisciplinary approach for laparoscopic removal of a large retroperitoneal pelvic schwannoma attached to vital vessels: A case report.

Medicine (Baltimore) 2019 Dec;98(51):e18149

Department of Vascular Surgery, Azienda Ospedaliera Brotzu, Cagliari, Italy.

Rationale: Retroperitoneal schwannomas are very rare and may grow very close to major abdominal vessels. Since the surgical approach to the retroperitoneal space may be complex due to surrounding vital organs, including major vessels, laparoscopic surgery is challenging and has only been recently adopted. Here, we report a case of laparoscopic resection of a large retroperitoneal schwannoma attached to large vital vessels. Read More

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December 2019

Step-by-step demonstration of laparoscopic laterally extended endopelvic resection for a recurrent endometrial cancerous tumor at a sciatic foramen, with a detailed explanation of the pelvic sidewall anatomy.

Gynecol Oncol 2020 01 27;156(1):260-261. Epub 2019 Nov 27.

Department of Gynecologic Oncology, Cancer Institute Hospital, 3-8-31 Ariake, Koutouku, Tokyo, 135-8550, Japan.

Objective: Laterally extended endopelvic resection (LEER) is regarded as a surgical salvage therapy for patients with laterally recurrent gynecologic carcinomas [1]. A prerequisite for R0 resection using this excision technique is carcinoma location remote from the sciatic foramen [1,2]. However, considering the advantages provided by laparoscopy in terms of visualization and dissection, laparoscopic LEER can potentially be used to achieve R0 resection of a laterally recurrent carcinoma at the sciatic foramen [3]. Read More

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January 2020

Extramedullary hematopoiesis: Clinical and cytological features.

Diagn Cytopathol 2020 Mar 27;48(3):191-196. Epub 2019 Nov 27.

Department of Cytology and Gynecologic Pathology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

Introduction: Hematopoiesis usually occurs in bone marrow in adults and when it occurs at sites except for bone marrow, it is termed as extramedullary hematopoiesis (EMH). It is usually found in organs, which are vigorously involved in fetal hematopoiesis, including liver, spleen, and lymph nodes. FNAC is easy and rapid method to diagnose EMH. Read More

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Tumor core biopsies adequately represent immune microenvironment of high-grade serous carcinoma.

Sci Rep 2019 11 26;9(1):17589. Epub 2019 Nov 26.

Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.

The prognostic and therapeutic value of the tumor microenvironment (TME) in various cancer types is of major interest. Characterization of the TME often relies on a small representative tissue sample. However, the adequacy of such a sample for assessing components of the TME is not yet known. Read More

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November 2019

Retrospective analysis of transvaginal ultrasound-guided aspiration of simple ovarian cysts.

Adv Clin Exp Med 2019 Nov;28(11):1531-1535

Polish Mother's Memorial Hospital Research Institute Department of Operative Gynecology and Gynecologic Oncology, Łódź, Poland.

Background: The widespread availability of ultrasonography means that transvaginal ultrasonography has become a routine procedure during gynecological examinations, even in asymptomatic patients. Nowadays the imaging technology offered by ultrasonography and tumor biomarkers give us an opportunity to implement transvaginal ultrasound-guided aspiration as a less radical treatment of simple ovarian cysts (SOC).

Objectives: The aim of the study was a retrospective evaluation of the diagnostic and therapeutic efficacy of transvaginal ultrasound-guided aspiration of SOC in postmenopausal and premenopausal patients. Read More

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November 2019

Role of transvaginal ultrasound-guided biopsy in gynecology.

Int J Gynecol Cancer 2020 01 23;30(1):128-132. Epub 2019 Oct 23.

Dipartimento per le Scienze della salute della donna e del bambino, Fondazione Policlinico Universitario A. Gemelli, IRCCS, Gynecologic Oncology, Rome, Italy.

Background: Ultrasound-guided biopsy is an easy technique for obtaining tissue samples. It is commonly used for different types of tumors, such as breast and prostate cancers, in order to plan early and adequate treatment.

Objective: To evaluate the indications, adequacy, and safety of transvaginal ultrasound-guided biopsy in women with pelvic lesions suspected of gynecologic malignancy. Read More

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January 2020

Sentinel Lymph Node Technique in Apparent Early Ovarian Cancer: Laparoscopic Technique.

J Minim Invasive Gynecol 2020 Jul - Aug;27(5):1019-1020. Epub 2019 Oct 16.

Department of Gynecologic Oncology, University Hospital La Fe (Drs. Lago, Matute, Padilla-Iserte, Marina, and Domingo).

Study Objective: To demonstrate the feasibility of laparoscopic sentinel lymph node technique in presumed early-stage ovarian cancer.

Design: Video illustrating the laparoscopic performance of the sentinel lymph node technique in ovarian cancer.

Setting: The Oncologic Gynecology Department at the University Hospital La Fe. Read More

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December 2020

Fine-needle aspiration cytology of chondroid syringoma.

Diagn Cytopathol 2019 Dec 1;47(12):1324-1325. Epub 2019 Oct 1.

Department of Cytology and Gynecologic Pathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

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December 2019

A Systematic Review of Tissue Sampling Techniques for the Diagnosis of Adenomyosis.

J Minim Invasive Gynecol 2020 02 6;27(2):344-351. Epub 2019 Sep 6.

Department of Minimally Invasive Gynecologic Surgery, Newton Wellesley Hospital, Newton, Massachusetts (all authors).

Objective: Evaluate the accuracy of tissue sampling techniques for the diagnosis of adenomyosis.

Data Sources: Systematic Review via MEDLINE and the Cochrane Library searches.

Methods Of Study Selection: Review performed utilizing the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, utilizing MeSH terms and keywords including "Adenomyosis/diagnosis" or "Adenomyosis/pathology" or "Myometrium/pathology" and "Biopsy" or "Hysteroscopy" or "Laparoscopy. Read More

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February 2020

Cystic swelling in a cervical lymph node: A diagnostic dilemma.

Cytopathology 2019 11 22;30(6):683-684. Epub 2019 Aug 22.

Department of Cytology and Gynecologic Pathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

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November 2019

Large pedunculated vulval fibroepithelial polyp.

BMJ Case Rep 2019 Jul 19;12(7). Epub 2019 Jul 19.

Obstetrics and Gynaecology, South West Health Campus, Bunbury, Western Australia, Australia.

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Artificial intelligence in cytopathology: a review of the literature and overview of commercial landscape.

J Am Soc Cytopathol 2019 Jul - Aug;8(4):230-241. Epub 2019 Mar 25.

Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.

Artificial intelligence (AI) has made impressive strides recently in interpreting complex images, thanks to improvements in deep learning techniques and increasing computational power. Researchers have started applying these advanced techniques to pathology images, although most efforts have been focused on histopathology. Cytopathology, however, remains the original field of pathology for which AI models for clinical use were successfully commercialized, to assist with automating Papanicolaou test screening. Read More

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The spectrum of malignant melanoma on cytology: A tertiary care center study.

Diagn Cytopathol 2019 Oct 1;47(10):1018-1023. Epub 2019 Jul 1.

Department of Cytology and Gynecologic Pathology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

Introduction: Malignant melanoma accounts for around 3% of all malignancies. Fine-needle aspiration cytology (FNAC) is a convenient diagnostic procedure for the diagnosis of melanoma and its metastases.

Aim: To explore the cytological spectrum of malignant melanoma including the rare metastatic sites. Read More

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October 2019

Diagnostic Utility and Safety of Endobronchial Ultrasound-guided Transbronchial Needle Aspiration in the Elderly.

J Bronchology Interv Pulmonol 2020 Jan;27(1):22-29

Departments of Pulmonary Medicine.

Background: There is limited evidence regarding the effect of age on the specimen adequacy, positivity rate of specimen on cytology (PR), and safety of endobronchial ultrasound (EBUS)-guided transbronchial needle aspiration (TBNA). The aim of this study was to investigate the utility of EBUS-TBNA in the elderly.

Methods: This was a retrospective study of subjects who underwent EBUS-TBNA. Read More

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January 2020