331 results match your criteria Gynecologic Needle Biopsy


Primary cytoreductive surgery with or without hyperthermic intraperitoneal chemotherapy (HIPEC) for FIGO stage III epithelial ovarian cancer: OVHIPEC-2, a phase III randomized clinical trial.

Int J Gynecol Cancer 2020 Jun 23;30(6):888-892. Epub 2020 Mar 23.

Department of Gynaecology, Netherlands Cancer Institute, Amsterdam, The Netherlands

Background: The addition of hyperthermic intraperitoneal chemotherapy (HIPEC) to interval cytoreductive surgery improves recurrence-free and overall survival in patients with FIGO stage III ovarian cancer who are ineligible for primary cytoreductive surgery. The effect of HIPEC remains undetermined in patients who are candidates for primary cytoreductive surgery.

Primary Objective: The primary objective is to evaluate the effect of HIPEC on overall survival in patients with FIGO stage III epithelial ovarian cancer who are treated with primary cytoreductive surgery resulting in no residual disease, or residual disease up to 2. Read More

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http://dx.doi.org/10.1136/ijgc-2020-001231DOI Listing

An interdisciplinary approach for laparoscopic removal of a large retroperitoneal pelvic schwannoma attached to vital vessels: A case report.

Medicine (Baltimore) 2019 Dec;98(51):e18149

Department of Vascular Surgery, Azienda Ospedaliera Brotzu, Cagliari, Italy.

Rationale: Retroperitoneal schwannomas are very rare and may grow very close to major abdominal vessels. Since the surgical approach to the retroperitoneal space may be complex due to surrounding vital organs, including major vessels, laparoscopic surgery is challenging and has only been recently adopted. Here, we report a case of laparoscopic resection of a large retroperitoneal schwannoma attached to large vital vessels. Read More

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http://dx.doi.org/10.1097/MD.0000000000018149DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6940178PMC
December 2019

Step-by-step demonstration of laparoscopic laterally extended endopelvic resection for a recurrent endometrial cancerous tumor at a sciatic foramen, with a detailed explanation of the pelvic sidewall anatomy.

Gynecol Oncol 2020 01 27;156(1):260-261. Epub 2019 Nov 27.

Department of Gynecologic Oncology, Cancer Institute Hospital, 3-8-31 Ariake, Koutouku, Tokyo, 135-8550, Japan.

Objective: Laterally extended endopelvic resection (LEER) is regarded as a surgical salvage therapy for patients with laterally recurrent gynecologic carcinomas [1]. A prerequisite for R0 resection using this excision technique is carcinoma location remote from the sciatic foramen [1,2]. However, considering the advantages provided by laparoscopy in terms of visualization and dissection, laparoscopic LEER can potentially be used to achieve R0 resection of a laterally recurrent carcinoma at the sciatic foramen [3]. Read More

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http://dx.doi.org/10.1016/j.ygyno.2019.11.015DOI Listing
January 2020

Retrospective analysis of transvaginal ultrasound-guided aspiration of simple ovarian cysts.

Adv Clin Exp Med 2019 Nov;28(11):1531-1535

Polish Mother's Memorial Hospital Research Institute Department of Operative Gynecology and Gynecologic Oncology, Łódź, Poland.

Background: The widespread availability of ultrasonography means that transvaginal ultrasonography has become a routine procedure during gynecological examinations, even in asymptomatic patients. Nowadays the imaging technology offered by ultrasonography and tumor biomarkers give us an opportunity to implement transvaginal ultrasound-guided aspiration as a less radical treatment of simple ovarian cysts (SOC).

Objectives: The aim of the study was a retrospective evaluation of the diagnostic and therapeutic efficacy of transvaginal ultrasound-guided aspiration of SOC in postmenopausal and premenopausal patients. Read More

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http://dx.doi.org/10.17219/acem/104549DOI Listing
November 2019

Role of transvaginal ultrasound-guided biopsy in gynecology.

Int J Gynecol Cancer 2020 01 23;30(1):128-132. Epub 2019 Oct 23.

Dipartimento per le Scienze della salute della donna e del bambino, Fondazione Policlinico Universitario A. Gemelli, IRCCS, Gynecologic Oncology, Rome, Italy.

Background: Ultrasound-guided biopsy is an easy technique for obtaining tissue samples. It is commonly used for different types of tumors, such as breast and prostate cancers, in order to plan early and adequate treatment.

Objective: To evaluate the indications, adequacy, and safety of transvaginal ultrasound-guided biopsy in women with pelvic lesions suspected of gynecologic malignancy. Read More

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http://dx.doi.org/10.1136/ijgc-2019-000734DOI Listing
January 2020
1 Read

Fine-needle aspiration cytology of chondroid syringoma.

Diagn Cytopathol 2019 Dec 1;47(12):1324-1325. Epub 2019 Oct 1.

Department of Cytology and Gynecologic Pathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

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http://dx.doi.org/10.1002/dc.24317DOI Listing
December 2019
1 Read

A Systematic Review of Tissue Sampling Techniques for the Diagnosis of Adenomyosis.

J Minim Invasive Gynecol 2020 Feb 6;27(2):344-351. Epub 2019 Sep 6.

Department of Minimally Invasive Gynecologic Surgery, Newton Wellesley Hospital, Newton, Massachusetts (all authors).

Objective: Evaluate the accuracy of tissue sampling techniques for the diagnosis of adenomyosis.

Data Sources: Systematic Review via MEDLINE and the Cochrane Library searches.

Methods Of Study Selection: Review performed utilizing the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, utilizing MeSH terms and keywords including "Adenomyosis/diagnosis" or "Adenomyosis/pathology" or "Myometrium/pathology" and "Biopsy" or "Hysteroscopy" or "Laparoscopy. Read More

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http://dx.doi.org/10.1016/j.jmig.2019.09.001DOI Listing
February 2020
1 Read

Large pedunculated vulval fibroepithelial polyp.

BMJ Case Rep 2019 Jul 19;12(7). Epub 2019 Jul 19.

Obstetrics and Gynaecology, South West Health Campus, Bunbury, Western Australia, Australia.

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http://dx.doi.org/10.1136/bcr-2019-230449DOI Listing
July 2019
8 Reads

The spectrum of malignant melanoma on cytology: A tertiary care center study.

Diagn Cytopathol 2019 Oct 1;47(10):1018-1023. Epub 2019 Jul 1.

Department of Cytology and Gynecologic Pathology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

Introduction: Malignant melanoma accounts for around 3% of all malignancies. Fine-needle aspiration cytology (FNAC) is a convenient diagnostic procedure for the diagnosis of melanoma and its metastases.

Aim: To explore the cytological spectrum of malignant melanoma including the rare metastatic sites. Read More

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http://dx.doi.org/10.1002/dc.24265DOI Listing
October 2019
7 Reads

Trends in Thyroid Fine-Needle Aspiration Cytology Practices: Results From a College of American Pathologists 2016 Practice Survey.

Arch Pathol Lab Med 2019 11 24;143(11):1364-1372. Epub 2019 May 24.

From the Gynecologic & Breast Pathology and Cytopathology Divisions, Joint Pathology Center, Silver Spring, Maryland (Dr Crothers); the Department of Pathology, University of Texas Health Sciences Center University Hospital, San Antonio (Drs Mais and Hackman); the Department of Pathology, University of Central Florida College of Medicine, Orlando (Dr Davey); Anatomic Pathology, Department of Pathology, Walter Reed National Military Medical Center, Bethesda, Maryland (Dr Natale); the Department of Pathology, Northwestern Memorial Hospital, Chicago, Illinois (Dr Nayar); Biostatistics and Surveys (Ms Souers) and Surveys, Cytopathology (Ms Blond), College of American Pathologists, Northfield, Illinois; and the Department of Pathology, St Joseph Mercy Hospital, Ann Arbor, Michigan (Dr Tworek).

Context.—: The College of American Pathologists periodically surveys laboratories to determine changes in cytopathology practices. We report the results of a 2016 survey concerning thyroid fine-needle aspiration (FNA). Read More

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http://www.archivesofpathology.org/doi/10.5858/arpa.2018-042
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http://dx.doi.org/10.5858/arpa.2018-0429-CPDOI Listing
November 2019
13 Reads
2.838 Impact Factor

Uterine Papillary Serous Carcinoma Arising in a Polyp: A Multicenter Retrospective Analysis on 75 Patients.

Am J Clin Oncol 2019 05;42(5):472-480

Unit of Obstetrics and Gynecology, Azienda USL-IRCCS of Reggio Emilia.

Objectives: The objectives of this study were to evaluate whether the international recommendations on the management of uterine papillary serous carcinoma arising in a polyp are uniformly followed in Italian Oncologic Centers and whether the strategy adopted is effective.

Materials And Methods: Patients with uterine papillary serous carcinoma arising in a polyp and who had undergone a hysterectomy were identified in the 2003-2013 database of 7 Italian Gynecologic Oncology Centers. Clinical and pathologic characteristics and outcomes were compared between staging procedure types. Read More

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http://dx.doi.org/10.1097/COC.0000000000000541DOI Listing
May 2019
6 Reads

Six months response rate of combined oral medroxyprogesterone/levonorgestrel-intrauterine system for early-stage endometrial cancer in young women: a Korean Gynecologic-Oncology Group Study.

J Gynecol Oncol 2019 Mar 7;30(2):e47. Epub 2019 Jan 7.

Department of Obstetrics and Gynecology, Ajou University School of Medicine, Suwon, Korea.

Objective: To evaluate the efficacy of combined oral medroxyprogesterone acetate (MPA)/levonorgestrel-intrauterine system (LNG-IUS) treatment and to compare the diagnostic accuracy of endometrial aspiration biopsy with dilatation & curettage (D&C) in young women with early-stage endometrial cancer (EC) who wished to preserve their fertility.

Methods: A prospective phase II multicenter study was conducted from January 2012 to January 2017. Patients with grade 1 endometrioid adenocarcinoma confined to the endometrium were treated with combined oral MPA (500 mg/day)/LNG-IUS. Read More

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http://dx.doi.org/10.3802/jgo.2019.30.e47DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393640PMC
March 2019
29 Reads
1.600 Impact Factor

Touch imprint (TI) cytology of needle core biopsies (NCB) in pathology laboratories: A practice survey of participants in the College of American Pathologists (CAP) Non Gynecologic Cytopathology (NGC) Education Program.

Diagn Cytopathol 2019 Mar 23;47(3):149-155. Epub 2018 Nov 23.

Department of Pathology and Immunology, Baylor College of Medicine, Ben Taub General Hospital, Houston, Texas.

Background: Intra-procedural assessment of touch imprint (TI) cytology from needle core biopsies (NCB) is used to ensure sample adequacy and to provide immediate diagnosis in various settings. We aimed to survey laboratories for current practices on the use of cytology with NCB.

Methods: A voluntary supplemental questionnaire including questions on demographics, personnel involved, sites, accessioning, and reporting was sent with the College of American Pathologists (CAP) 2015 Non gynecologic Cytopathology Education Program to survey practices of cytologic assessment of NCB. Read More

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http://dx.doi.org/10.1002/dc.24023DOI Listing
March 2019
9 Reads

Development of Patient-Derived Tumor Xenograft Models.

Methods Mol Biol 2019 ;1862:217-225

Gynecological Oncology, Oncology Department, LKI Leuven Cancer Institute KU Leuven-University of Leuven, Leuven, Belgium.

In spite of the latest advancements in understanding cancer development and progression, drugs successful in preclinical testing often fail upon reaching phase III clinical trials. A reason for this is the use of inappropriate preclinical models that do not preserve tumor heterogeneity. Although used for decades, cell cultures derived from patients substantially deviate from their original biopsy upon culturing; moreover, they cannot predict the response of an organism as a whole. Read More

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http://dx.doi.org/10.1007/978-1-4939-8769-6_15DOI Listing
June 2019
9 Reads

Gastrointestinal Endoscopic Ultrasound-Guided Fine-Needle Aspiration for Assessing Suspected Deep Pelvic or Abdominal Recurrence in Gynecologic Cancer: A Feasibility Study.

J Ultrasound Med 2019 Mar 31;38(3):761-765. Epub 2018 Aug 31.

Department of Obstetrics and Gynecology, Clinica Universidad de Navarra, Pamplona, Spain.

Objectives: To assess the feasibility of gastrointestinal endoscopic ultrasound (EUS)-guided fine-needle aspiration (FNA) for histologic confirmation of cancer recurrence in women with gynecologic cancer.

Methods: This work was a retrospective cohort study comprising 46 consecutive women treated for gynecologic cancer and suspected of having a deep pelvic or abdominal recurrence on ultrasound imaging, computed tomography, positron emission tomography-computed tomography, or magnetic resonance imaging, evaluated at our institution from January 2010 to December 2017. Primary cancer was ovarian (n = 22), cervical (n = 13), endometrial (n = 4), sarcoma (n = 4), and other (n = 3). Read More

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http://dx.doi.org/10.1002/jum.14766DOI Listing
March 2019
23 Reads

Fine needle aspiration cytology of a recurrent parotid tumour.

Cytopathology 2019 01 24;30(1):119-120. Epub 2018 Sep 24.

Department of Cytology and Gynecologic Pathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

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http://dx.doi.org/10.1111/cyt.12623DOI Listing
January 2019
17 Reads

Factors affecting pain during outpatient clinic based surgical procedures in gynecologic oncology.

Medicine (Baltimore) 2018 Aug;97(31):e11721

Department of Obstetrics and Gynecology, Seoul National University Bundang Hospital, Seongnam-Si, Gyeonggi-Do.

Colposcopy-directed punch biopsy (punch biopsy) and endocervical curettage (ECC) are accompanied by considerable pain. However, many physicians perform these procedures without adequate pain management. Therefore, identification of factors affecting pain experienced during the procedures may encourage physician effort in selective pain management. Read More

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http://dx.doi.org/10.1097/MD.0000000000011721DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081132PMC
August 2018
18 Reads
5.720 Impact Factor

A Randomized Trial Evaluating the Effect of 10 versus 20 Revolutions Inside the Lymph Node on the Diagnostic Yield of EBUS-TBNA in Subjects with Sarcoidosis.

Respiration 2018;96(5):464-471. Epub 2018 Jul 24.

Department of Pulmonary Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Background: Endobronchial ultrasound (EBUS)-guided transbronchial needle aspiration (TBNA) is the preferred modality for sampling intrathoracic lymph nodes in patients with suspected sarcoidosis. Whether the number of revolutions of the needle inside the lymph node while performing TBNA affects the diagnostic yield is unknown.

Objectives: The aim of this paper was to compare the yield of different numbers of needle revolutions (10 vs. Read More

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https://www.karger.com/Article/FullText/490192
Publisher Site
http://dx.doi.org/10.1159/000490192DOI Listing
October 2019
5 Reads
2.593 Impact Factor

Pelvic and pulmonary benign metastasizing leiomyoma: A case report.

Case Rep Womens Health 2018 Apr 31;18:e00061. Epub 2018 Mar 31.

Center for Infertility and Reproductive Surgery, Department of Obstetrics, Gynecology, and Reproductive Biology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

Seven years after she had a total abdominal hysterectomy for benign leiomyomas, a 46-year-old woman presented with a pelvic mass and multiple pulmonary nodules. She underwent resection of the mass and core needle biopsy of a pulmonary lesion. Histopathologic analysis revealed that both the pelvic and the pulmonary lesions were consistent with benign leiomyomas. Read More

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http://dx.doi.org/10.1016/j.crwh.2018.e00061DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5960028PMC
April 2018
13 Reads

Ultrasound-guided follicle aspiration at time of laparotomy in a patient with Mayer-Rokitansky-Küster-Hauser syndrome.

Fertil Steril 2018 05;109(5):940

Department of Reproductive Endocrinology and Infertility, Washington University, St. Louis, Missouri.

Objective: To demonstrate a unique case of direct ultrasound-guided follicle aspiration at time of a laparotomy in a patient with Mayer-Rokitansky-Küster-Hauser Syndrome.

Design: Video presentation.

Setting: Academic fertility center PATIENT(S): A 32-year-old gravida 0 with Mayer-Rokitansky-Küster-Hauser Syndrome and bilateral ovarian masses presented as a fertility preservation consult from gynecologic oncology due to the possibility of bilateral oophorectomy. Read More

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http://dx.doi.org/10.1016/j.fertnstert.2018.02.007DOI Listing
May 2018
22 Reads

International telecytology: Current applications and future potential.

Diagn Cytopathol 2019 Jan 4;47(1):28-34. Epub 2018 May 4.

Department of Pathology & Laboratory Medicine, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, California 90025.

International telecytology can improve patient care by increasing access to regional and international expertise in cytopathology. The majority of international telecytology studies published to date have been based on static telepathology platforms. Overall concordance rates for these studies ranged from 71% to 93%. Read More

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http://doi.wiley.com/10.1002/dc.23960
Publisher Site
http://dx.doi.org/10.1002/dc.23960DOI Listing
January 2019
25 Reads

Aspiration cytology of a scalp lump.

Cytopathology 2018 10 1;29(5):492-493. Epub 2018 May 1.

Department of Cytology and Gynecologic Pathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

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http://dx.doi.org/10.1111/cyt.12549DOI Listing
October 2018
2 Reads

Sarcoid-Like Mediastinal Lymphadenopathy in Gynecologic Malignancy.

Pulm Med 2018 14;2018:5141575. Epub 2018 Feb 14.

Pulmonary-Critical Care Medicine, Abington Jefferson Health, Abington, PA, USA.

Noncaseating granulomas are seen surrounding tumors with varying frequency, possibly as part of an immune response to tumor cells. However, data about the association of sarcoid with gynecologic malignancy is sparse. We performed a search of our institutional database for all EBUS-TBNA biopsies conducted within the past five years that revealed granulomatous inflammation. Read More

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https://www.hindawi.com/journals/pm/2018/5141575/
Publisher Site
http://dx.doi.org/10.1155/2018/5141575DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832114PMC
January 2019
11 Reads

Suitability of the Cellient cell block method for diagnosing soft tissue and bone tumors.

Diagn Cytopathol 2018 Apr 10;46(4):299-305. Epub 2018 Jan 10.

Department of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, P.O. Box 30.001, RB Groningen, 9700, The Netherlands.

Background: The diagnosis of tumors of soft tissue and bone (STB) heavily relies on histological biopsies, whereas cytology is not widely used. Cellient cell blocks often contain small tissue fragments. In addition to Hematoxylin and Eosin (H&E) interpretation of histological features, immunohistochemistry (IHC) can be applied after optimization of protocols. Read More

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http://doi.wiley.com/10.1002/dc.23887
Publisher Site
http://dx.doi.org/10.1002/dc.23887DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5888188PMC
April 2018
26 Reads

Treatment of Low-Risk Endometrial Cancer and Complex Atypical Hyperplasia With the Levonorgestrel-Releasing Intrauterine Device.

Obstet Gynecol 2018 01;131(1):109-116

Department of Gynecologic Oncology and Reproductive Medicine and the Division of Quantitative Sciences, University of Texas MD Anderson Cancer Center, Houston, Texas.

Objective: To assess efficacy of the levonorgestrel-releasing intrauterine device (LNG-IUD) for treatment of complex atypical hyperplasia or low-grade endometrial cancer.

Methods: This retrospective case series included all patients treated with the LNG-IUD for complex atypical hyperplasia or early-grade endometrial cancer from January 2003 to June 2013. Response rates were calculated and the association of response with clinicopathologic factors, including age, body mass index, and uterine size, was determined. Read More

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http://dx.doi.org/10.1097/AOG.0000000000002390DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739955PMC
January 2018
54 Reads

Cytomorphologic features of metastatic endometrioid carcinoma by fine needle aspiration.

Diagn Cytopathol 2018 Feb 4;46(2):105-110. Epub 2017 Nov 4.

Department of Pathology, The University of Chicago, Chicago, Illinois.

Background: Although metastatic disease is commonly seen in high grade carcinomas of gynecologic origin, it also occurs in low to intermediate grade endometrioid carcinomas (LGEMCAs), and may even be the primary presentation of disease. Tissue confirmation is necessary to guide therapy, but performing biopsies might not always be feasible or practical. In such instances, fine needle aspiration (FNA) is a safe and efficient alternative. Read More

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http://dx.doi.org/10.1002/dc.23855DOI Listing
February 2018
35 Reads

Performance of ovarian cyst fluid fine-needle aspiration cytology.

Cancer Cytopathol 2018 02 21;126(2):112-121. Epub 2017 Aug 21.

Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland.

Background: Although ovarian fine-needle aspiration (FNA) cytology is not commonly used as a primary modality of diagnosis for patients with ovarian lesions, many ovarian cysts are aspirated intraoperatively and occasionally for diagnostic purposes. Therefore, the ability to interpret these specimens remains critical. Previous studies have suggested a high specificity but low sensitivity as a limitation. Read More

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http://dx.doi.org/10.1002/cncy.21911DOI Listing
February 2018
9 Reads

Three-year cytohistological correlation of salivary gland FNA cytology at a tertiary center with the application of the Milan system for risk stratification.

Cancer Cytopathol 2017 Oct 7;125(10):767-775. Epub 2017 Aug 7.

Department of Histopathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Background: Fine-needle aspiration (FNA) cytology of salivary glands is a well-established technique that plays a critical role in the preoperative diagnosis of lesions. A risk stratification of FNA diagnostic categories has been recently proposed to be useful in reporting. The aims of this study were to evaluate the diagnostic accuracy of salivary gland FNA and to apply the proposed Milan system for reporting salivary gland lesions. Read More

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http://dx.doi.org/10.1002/cncy.21900DOI Listing
October 2017
86 Reads

Laparoscopic Minimally Invasive Approach to Sentinel Lymph Node Mapping of the Ovary Using the Near-infrared Fluorescent S1 HD Pinpoint System with Indocyanine Green Dye.

J Minim Invasive Gynecol 2018 02 29;25(2):336-337. Epub 2017 Jul 29.

Gynecologic Oncology Unit, Department of Obstetrics and Gynecology, San Gerardo Hospital, University of Milano-Bicocca, Monza, Italy.

Study Objective: To show a novel minimally invasive approach to sentinel lymph node (SLN) detection of the ovary with near-infrared-guided surgery using indocyanine green (ICG).

Design: A step by step description of the technique with video and figures (educational video).

Setting: The standard surgical staging of early-stage I-II ovarian cancer includes systematic pelvic and aortic lymphadenectomy even in the absence of clear evidence regarding the survival benefits associated with comprehensive retroperitoneal staging. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S15534650173040
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http://dx.doi.org/10.1016/j.jmig.2017.07.018DOI Listing
February 2018
30 Reads

The evolving role of cytopathology in the era of neoadjuvant chemotherapy for the accurate pathologic diagnosis of epithelial ovarian cancer.

Authors:
Elise N Everett

Cancer Cytopathol 2017 10 31;125(10):743-744. Epub 2017 Jul 31.

Associate Professor of Gynecologic Oncology, Department of Obstetrics, Gynecology, and Reproductive Sciences, Larner College of Medicine at the University of Vermont, Burlington, Vermont.

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http://dx.doi.org/10.1002/cncy.21894DOI Listing
October 2017
7 Reads

Fine-needle aspiration cytology in primary cutaneous tumors.

Diagn Cytopathol 2017 Aug 4;45(8):681-688. Epub 2017 May 4.

Department of Cytology and Gynecologic Pathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Background: Fine-needle aspiration biopsy (FNAB) is occasionally used in the evaluation of primary skin tumors. However, in routine evaluation of any soft tissue swelling we encounter the cases of skin lesions. It is essential to know FNAB features of skin lesions. Read More

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http://dx.doi.org/10.1002/dc.23741DOI Listing
August 2017
49 Reads

Impact of Preoperative Breast MR Imaging and MR-guided Surgery on Diagnosis and Surgical Outcome of Women with Invasive Breast Cancer with and without DCIS Component.

Radiology 2017 09 26;284(3):645-655. Epub 2017 Apr 26.

From the Department of Diagnostic and Interventional Radiology (C.K.K., K.S., S.S.), Section of Bioinformatics, Department of Diagnostic and Interventional Radiology (H.B.), and Department of Gynecology and Gynecologic Oncology (N.M.), University of Aachen, RWTH, Pauwelsstr 30, 52074 Aachen, Germany; Department of Pathology, University of Muenster, Muenster, Germany (E.W.); and Department of Gynecology, University of Bonn, Bonn, Germany (W.K.).

Purpose To (a) compare the diagnostic accuracy of breast magnetic resonance (MR) imaging with that of conventional imaging (digital mammography and breast ultrasonography) in the identification of ductal carcinoma in situ (DCIS) components of biopsy-proven invasive breast cancer before surgery and (b) investigate the surgical outcome (positive margin rates and mastectomy rates) of women with breast cancer who underwent preoperative MR imaging combined with MR-guided needle biopsy and/or MR-guided lesion localization or bracketing where appropriate. Materials and Methods The authors performed a prospective two-center study of 593 consecutive patients with biopsy-proven invasive breast cancer who underwent breast MR imaging in addition to conventional imaging. MR-guided vacuum biopsy and MR-guided lesion bracketing were performed for DCIS components visible at MR imaging alone. Read More

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http://dx.doi.org/10.1148/radiol.2017161449DOI Listing
September 2017
35 Reads

Agreement between cytotechnologists and cytopathologists as a new measure of cytopathologist performance in gynecologic cytology.

Cancer Cytopathol 2017 Jul 27;125(7):576-580. Epub 2017 Mar 27.

Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.

Background: Although objective measures of cytotechnologist (CT) and cytopathologist (CP) performance exist, challenges remain. Two assumptions deserve examination: CPs' interpretations are correct, and CTs and CPs render interpretations independently of each other. This study presents a CT-CP interpretation comparison and provides insight into these assumptions. Read More

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http://dx.doi.org/10.1002/cncy.21856DOI Listing
July 2017
33 Reads

Changing Trends and Practices in Cytopathology.

Acta Cytol 2017 22;61(2):91-95. Epub 2017 Mar 22.

Department of Pathology, University of Mississippi Medical Center, Jackson, MS, USA.

Objective: To explore the current and anticipated changes in the practice of cytopathology.

Study Design: The present review is based on a review of recent literature and an evaluation of the authors' personal experiences.

Results And Conclusion: In recent years the practice of cytopathology, nationwide and in our institute, has witnessed a major change affecting gynecologic and nongynecologic cytology. Read More

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http://dx.doi.org/10.1159/000460236DOI Listing
May 2017
17 Reads

Needleoscopic Conservative Staging of Borderline Ovarian Tumor.

J Minim Invasive Gynecol 2017 May - Jun;24(4):529-530. Epub 2016 Oct 27.

Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Catholic University of the Sacred Heart, Rome, Italy.

Study Objective: To investigate the safety and technical feasibility of needleoscopic fertility-sparing staging of borderline ovarian tumors.

Design: Video article and review of the literature (Canadian Task Force classification Level III).

Setting: This 29-year-old woman had a right ovarian cyst suspicious for borderline ovarian tumor on preoperative magnetic resonance imaging and ultrasound showing the presence of a right unilocular ovarian cyst with a papillary projection. Read More

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http://dx.doi.org/10.1016/j.jmig.2016.10.009DOI Listing
December 2017
19 Reads

Endometriosis-associated clear cell carcinoma arising in caesarean section scar: a case report and review of the literature.

World J Surg Oncol 2016 Dec 3;14(1):300. Epub 2016 Dec 3.

Department Pathology, Catholic University, Rome, Italy.

Background: Malignant transformation has been reported in approximately 1% of the endometriosis cases; herein, we report a case of clear cell endometrial carcinoma arising from endometriosis foci located within a caesarean section scar.

Case Presentation: In November 2014, a Caucasian, 44-year-old woman was transferred to our institution because of severe respiratory failure due to massive lung embolism and rapid enlargement of a subcutaneous suprapubic mass. Abdomino-pelvic magnetic resonance showed a 10. Read More

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http://dx.doi.org/10.1186/s12957-016-1054-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135835PMC
December 2016
50 Reads

Successful application of endoscopic ultrasound-guided fine needle biopsy to establish pancreatic patient-derived tumor xenografts: a pilot study.

Endoscopy 2016 Nov 14;48(11):1016-1022. Epub 2016 Sep 14.

Laboratory of Gynecologic Oncology, Department of Oncology, University of Leuven, Leuven, Belgium.

Typically, pancreatic patient-derived tumor xenografts (PDXs) are established by transplanting large tumor biopsies obtained through invasive surgery approaches into immunocompromised mice. We aimed to develop pancreatic PDXs by transplanting tumor tissue acquired by endoscopic ultrasound (EUS)-guided fine needle biopsies (FNB), assess take rates compared to surgery-derived PDXs, and demonstrate the histological and genetic resemblance to the original tumor. Biopsies of untreated pancreatic carcinoma were collected at surgery and during EUS and processed to generate PDXs. Read More

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http://dx.doi.org/10.1055/s-0042-113597DOI Listing
November 2016
46 Reads

Pregnancy-associated Breast Cancer.

Authors:
Ashley S Case

Clin Obstet Gynecol 2016 12;59(4):779-788

Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Mountain Area Health Education Center, Hope Women's Cancer Center, Asheville, North Carolina.

Breast cancer is one of the most common malignancies affecting pregnancy. Pregnancy-associated breast cancer refers to breast cancer that is diagnosed during pregnancy or within the first postpartum year. The incidence is increasing as more women delay childbearing. Read More

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http://dx.doi.org/10.1097/GRF.0000000000000235DOI Listing
December 2016
21 Reads

Sensitivity of Follow-Up Methods in Patients After Fertility-Sparing Surgery for Cervical Cancers.

Int J Gynecol Cancer 2017 01;27(1):147-153

*1st Faculty of Medicine, Department of Gynecology and Obstetrics, Gynecologic Oncology Centre, Charles University and General University Hospital in Prague; and †Institute of Biostatistics and Analyses, Masaryk University, Brno, Czech Republic.

Objective: The aim of our study was to compare the sensitivity of various methods and their combinations in the follow-up of patients with cervical cancer after fertility-sparing surgery (FSS).

Methods: Included were women with cervical cancer in stages IA2 to IB2 who underwent FSS, which includes pelvic lymphadenectomy, sentinel lymph node biopsy, abdominal radical trachelectomy, vaginal trachelectomy, or needle conization. Follow-up visits were scheduled at 3-month intervals and included symptom-oriented discussion, gynecological and physical examination, colposcopy, Papanicolaou test, human papillomavirus (HPV) DNA test, and ultrasound examination. Read More

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http://dx.doi.org/10.1097/IGC.0000000000000835DOI Listing
January 2017
34 Reads

Percutaneous image-guided pelvic procedures in women with gynecologic cancers: utilization, complications, and impact on patient management.

Abdom Radiol (NY) 2016 12;41(12):2460-2465

Department of Radiology, University of Michigan, 1500 E. Medical Center Drive, Ann Arbor, MI, 48109-5030, USA.

Purpose: Image-guided percutaneous pelvic procedures often play an important role in the management of women with gynecologic cancers. The purpose of this study is to evaluate the utilization of and indications for these procedures, and quantify their impact on patient management.

Methods: IRB-approved retrospective record review of percutaneous pelvic procedures requested by gynecologic oncology, 2005 to 2015. Read More

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http://dx.doi.org/10.1007/s00261-016-0882-9DOI Listing
December 2016
37 Reads

Vaginal fine-needle aspiration: A useful alternative to biopsy.

Diagn Cytopathol 2016 Aug 24;44(8):665-9. Epub 2016 May 24.

Rush University Medical Center, Chicago, Illinois.

Background: Vaginal fine-needle aspiration (FNA) is infrequently performed to assess palpable lesions. We perform the first multi-institutional study to evaluate this procedure.

Methods: We retrospectively reviewed vaginal FNAs performed at two institutions for the past 27 years. Read More

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http://dx.doi.org/10.1002/dc.23504DOI Listing
August 2016
33 Reads

Transvaginal Ultrasound-Guided Biopsy of Deep Pelvic Masses: How We Do It.

J Ultrasound Med 2016 Jun 18;35(6):1113-22. Epub 2016 Apr 18.

Department of Radiology and Biomedical Imaging, University of California, San Francisco, California USA.

The purpose of this review is to discuss the rationale and indications for transvaginal ultrasound-guided biopsy. Transvaginal ultrasound-guided biopsy can be a helpful tool for diagnosis and treatment planning in the evaluation of pelvic masses, particularly when the anatomy precludes a transabdominal or posterior transgluteal percutaneous biopsy approach. A step-by-step summary of the technique with preprocedure and postprocedure considerations is included. Read More

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http://dx.doi.org/10.7863/ultra.15.08002DOI Listing
June 2016
15 Reads

Management of Endometrial Hyperplasia With a Levonorgestrel-Releasing Intrauterine System: A Korean Gynecologic-Oncology Group Study.

Int J Gynecol Cancer 2016 May;26(4):711-5

*Departments of Obstetrics and Gynecology, CHA Gangnam Medical Center, CHA University; †Seoul National University College of Medicine, Seoul; ‡Soonchunhyang University Cheonan Hospital, Soonchunhyang University College of Medicine, Cheonan; §Chonnam National University Medical School, Gwangju; ∥Cheil General Hospital and Women's Healthcare Center, Dankook University College of Medicine, Seoul; ¶Gyeongsang National University School of Medicine, Jinju,; #Ewha Womans University Mokdong Hospital, Ewha Womans University School of Medicine, Seoul; **Inha University College of Medicine, Incheon; ††CHA Bundang Medical Center, CHA University, Bundang; ‡‡Ajou University School of Medicine, Suwon; §§Sanggye Paik Hospital, Inje University College of Medicine; and ∥∥Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Korea.

Objective: The aim of the study was to evaluate the efficacy of the levonorgestrel intrauterine system (LNG-IUS) for treatment of endometrial hyperplasia (EH).

Methods: A prospective multicenter study was conducted from November 2010 to March 2014. Patients with histologically confirmed EH were treated with LNG-IUS. Read More

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http://dx.doi.org/10.1097/IGC.0000000000000669DOI Listing
May 2016
52 Reads

The Utility of Core Needle Biopsy and Fine-Needle Aspiration in the Workup of Tumors of Suspected Müllerian Origin.

Acta Cytol 2015 11;59(6):465-73. Epub 2016 Feb 11.

Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Tex., USA.

Objectives: Core needle biopsy (CNB) and fine-needle aspiration (FNA) for tumors of suspected Müllerian origin may prevent unnecessary laparotomies and allow patients the benefit of neoadjuvant chemotherapy. An assessment of the utility and limitations of CNB/FNA, with incorporation of current immunohistochemistry, is needed.

Study Design: Two hundred nineteen female patients with CNB/FNA of the omentum, pelvis, abdomen, adnexa, ovary, uterus, and fallopian tube were identified. Read More

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http://dx.doi.org/10.1159/000443517DOI Listing
July 2016
18 Reads

Comparison of EASYPREP(®) and SurePath(®) in thyroid fine-needle aspiration.

Diagn Cytopathol 2016 Apr 5;44(4):283-90. Epub 2016 Feb 5.

Department of Hospital Pathology, the Catholic University of Korea, Seoul, Republic of Korea.

Background: While fine-needle aspiration cytology (FNAC) using conventional smear has been widely accepted as the primary diagnostic tool for thyroid lesions, liquid-based preparations (LBPs) are increasingly replacing it. A new automated LBP method, EASYPREP(®) (EP), was recently introduced and has shown relevant diagnostic efficacy in gynecologic samples. We compared the diagnostic utility of EP and SurePath(®) (SP), a more widely established LBP method, in thyroid FNAC. Read More

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http://doi.wiley.com/10.1002/dc.23438
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http://dx.doi.org/10.1002/dc.23438DOI Listing
April 2016
38 Reads

Is adjuvant chemotherapy indicated in ovarian immature teratomas? A combined data analysis from the Malignant Germ Cell Tumor International Collaborative.

Cancer 2016 Jan 20;122(2):230-7. Epub 2015 Oct 20.

Dana-Farber Cancer Institute and Boston Children's Hospital, Boston, Massachusetts.

Background: There is a debate regarding the management of ovarian immature teratomas (ITs). In adult women, postoperative chemotherapy is standard except for stage I, grade 1 disease, whereas surgery alone is standard in pediatric patients. To determine the role of chemotherapy, a pooled analysis of pediatric and adult clinical trials was conducted. Read More

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http://dx.doi.org/10.1002/cncr.29732DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5134834PMC
January 2016
95 Reads

Povidone Iodine Rectal Preparation at Time of Prostate Needle Biopsy is a Simple and Reproducible Means to Reduce Risk of Procedural Infection.

J Vis Exp 2015 Sep 21(103). Epub 2015 Sep 21.

Department of Veterinary and Biomedical Sciences, Penn State University.

Single institution and population-based studies highlight that infectious complications following transrectal ultrasound guided prostate needle biopsy (TRUS PNB) are increasing. Such infections are largely attributable to quinolone resistant microorganisms which colonize the rectal vault and are translocated into the bloodstream during the biopsy procedure. A povidone iodine rectal preparation (PIRP) at time of biopsy is a simple, reproducible method to reduce rectal microorganism colony counts and therefore resultant infections following TRUS PNB. Read More

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http://dx.doi.org/10.3791/52670DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692615PMC
September 2015
13 Reads

Management of Vulvar Cancer.

Rev Recent Clin Trials 2015 ;10(4):282-8

Department of Obstetrics & Gynecology, University College of Medical Sciences & Guru Teg Bahadur Hospital, Delhi 110095.

Vulvar cancer is an uncommon malignancy and accounts for around 5% of all gynecologic cancers. Incidence rates have increased for young adults and may be linked to increasing HPV prevalence. Treatment of vulvar cancer has evolved from 'en-bloc' surgery with high morbidity to more conservative approaches without compromising oncological safety. Read More

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http://dx.doi.org/10.2174/1574887110666150923112723DOI Listing
August 2016
38 Reads

Management of Vaginal Cancer.

Rev Recent Clin Trials 2015 ;10(4):289-97

BIMR Oncology Centre, BIMR Hospitals, Gwalior (M.P.), India.

Context: Vaginal cancer is a rare gynecologic cancer with very little documentation.

Objective: Literature search to have useful information for the management of vaginal cancer and share.

Material Methods: We have searched the PUBMED database, Google search engine and other database. Read More

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http://dx.doi.org/10.2174/1574887110666150923112958DOI Listing
August 2016
58 Reads

Optimizing Strategies for Sentinel Lymph Node Mapping in Early-Stage Cervical and Endometrial Cancer: Comparison of Real-Time Fluorescence With Indocyanine Green and Methylene Blue.

Int J Gynecol Cancer 2015 Oct;25(8):1513-8

*Gynecologic Oncology Unit, Department of Obstetrics and Gynecology, San Gerardo Hospital; and †University of Milano-Bicocca, Monza, Italy.

Objective: This retrospective study aimed to compare the sentinel lymph node (SLN) mapping results of methylene blue (MB) and indocyanine green (ICG) in women with early-stage endometrial or cervical cancer.

Methods: From August 2011 to March 2015, all consecutive patients with stage I endometrial or cervical cancer who underwent SLN mapping with intracervical injection of MB or ICG using a 22-gauge spinal needle were included in the study. Radical or simple hysterectomy with bilateral pelvic and/or aortic lymphadenectomy was performed after SLN mapping. Read More

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http://dx.doi.org/10.1097/IGC.0000000000000526DOI Listing
October 2015
29 Reads