Search Our Scientific Publications & Authors

J Surg Case Rep 2022 Jun 10;2022(6):rjac166. Epub 2022 Jun 10.

Department of Pathology, Institut Claudius Regaud-Institut Universitaire du Cancer de Toulouse (IUCT), Oncopole, Toulouse, France.

Disseminated peritoneal leiomyomatosis (DPL) is a rare gynecologic disease involving multifocal proliferation of myomas. The pathogenesis remains unclear. Although there is no standard treatment, medical therapies have attempted to suppress estrogen levels by using gonadotrophin-releasing hormone agonist and aromatase inhibitor (AI) therapy with differing degrees of success. Read More

Fertil Steril 2022 Jun 9. Epub 2022 Jun 9.

Division of Minimally Invasive Gynecologic Surgery, Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, Texas. Electronic address:

Objective: To describe a novel, minimally invasive technique for performing myomectomy, a fertility-sparing procedure.

Design: This technique was developed based on similar techniques for other surgeries that showed a benefit. Liu et al. Read More

Obstet Gynecol Clin North Am 2022 Jun;49(2):329-353

Minimally Invasive Gynecologic Surgery, Mayo Clinic, 4500 San Pablo Road South, Jacksonville, FL 32224, USA.

Hysteroscopic myomectomy is the treatment of choice for symptomatic submucosal myomas, with excellent success rate and low complication rate. Read More

Diagnostics (Basel) 2022 May 9;12(5). Epub 2022 May 9.

Division of Gynecology and Obstetrics, Department of Surgical Sciences, University of Cagliari, 09124 Cagliari, Italy.

Abnormal uterine bleeding (AUB) is a frequent symptom in perimenopausal women. It is defined as uterine bleeding in which the duration, frequency, or amount of bleeding is considered excessive and negatively affects the woman's quality of life (QoL) and psychological well-being. In cases of structural uterine pathology, hysterectomy (usually performed via a minimally invasive approach) offers definitive symptom relief and is associated with long-lasting improvement of QoL and sexuality. Read More

J Minim Invasive Gynecol 2022 Apr 29. Epub 2022 Apr 29.

Division of Minimally Invasive Gynecologic Surgery, Baylor College of Medicine, Houston, Texas (Drs. Zi, Ding, Thigpen, and Guan). Electronic address:

Study Objective: To demonstrate tips and tricks for the successful use of single-site laparoscopic surgery for pedunculated myomectomy during pregnancy.

Design: Stepwise demonstration with narrated video footage.

Setting: An academic tertiary care hospital affiliated with Baylor College of Medicine. Read More

Am J Obstet Gynecol 2022 Apr 27. Epub 2022 Apr 27.

Department of Obstetrics and Gynecology, Cedars-Sinai Medical Center, Los Angeles, CA.

Background: Simulation is an important adjunct to traditional surgical training, allowing for repetitive practice of new skills without compromising patient safety. Although several simulation models have been described and evaluated for gynecologic procedures, there is a lack of such models for laparoscopic myomectomy.

Objective: This study aimed to design a low-cost, low-fidelity laparoscopic myomectomy simulation model and to assess the model's validity as a training tool. Read More

Medicina (Kaunas) 2022 Apr 17;58(4). Epub 2022 Apr 17.

Department of Gynecologic Oncology and Minimally-Invasive Gynecologic Surgery, Università degli Studi di Messina, Policlinico G. Martino, 98124 Messina, Italy.

Since the Food and Drug Administration's (FDA) approval in 2005, the application of robotic surgery (RS) in gynecology has been adopted all over the world. This study aimed to provide an update on RS in benign gynecological pathology by reporting the scientific recommendations and high-value scientific literature available to date. A systematic review of the literature was performed. Read More

Surg Technol Int 2022 May;40:190-196

Department of Women's Health, Tuebingen University Hospital, Tuebingen, Germany.

Electrosurgery in gynecology has changed over the past few decades. The use of energy-based devices, especially in minimally invasive procedures, is extremely important for preparation, short reconvalescence and patient safety. Recently, there have been major advances in energy-based surgical devices that have further shortened OR time and increased patient safety. Read More

Abdom Radiol (NY) 2022 Jun 26;47(6):2197-2208. Epub 2022 Mar 26.

Department of Medical Imaging and Intervention, Chang Gung Memorial Hospital at Linkou, 5 Fuhsing St., Guishan, Taoyuan, 33382, Taiwan.

Uterine leiomyoma, also known as uterine fibroid, is the most common gynecological tumor, affecting almost 80% of women at some point during their lives. In the same time, other fibroid-like tumors have similar clinical presentations and about 0.5% of resected tumors of which were presumed benign fibroids in the preoperative diagnosis revealed as malignant sarcomas in the final histopathological examination. Read More

Ginekol Pol 2022 Mar 22. Epub 2022 Mar 22.

The Second Affiliated Hospital of Soochow University, Gusu District, Suzhou, China, China.

Objectives: Open power morcellation during a laparoscopic myomectomy (LM) can result in the dissemination of benign or occult malignant tumor cells in the abdominopelvic cavity. The development of a new contained collection bag for power morcellation is now favored by gynecologic surgeons worldwide.

Material And Methods: This study was a single-arm trial comprising 20 women who consecutively underwent an LM involving the use of a newly designed contained collection bag for power morcellation between November 3rd 2017 and April 31st 2018. Read More

Gynecol Minim Invasive Ther 2022 Jan-Mar;11(1):47-50. Epub 2022 Feb 14.

Cambridge Endometriosis and Endoscopic Surgery Unit, Cambridge University Hospitals NHS Foundation Trust, Cambridge, England.

Leiomyomas are the most common uterine benign tumor, and their malignant counterpart leiomyosarcomas are extremely rare. Despite this, a preoperative diagnosis could be useful for safe surgical minimally invasive management. At present, some clinical and ultrasound findings help recognizing lesions at risk of malignancy. Read More

Wiad Lek 2022 ;75(2):545-550

DEPARTMENT OF GYNECOLOGIC ONCOLOGY, MEDICAL UNIVERSITY PLEVEN,PLEVEN, BULGARIA.

Uterine fibroids are the most common benign gynecological neoplasms, with a higher prevalence in women aged between 30 and 50 years old. Fibroids may be asymptomatic, but in some cases, they can affect seriously the quality of life of the patients. In some cases, we can recommend expectant management for asymptomatic patients. Read More

Taiwan J Obstet Gynecol 2022 Jan;61(1):75-79

Department of Obstetrics and Gynecology, Fibroid Center, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, 222, Banpo-daero, Seocho-Gu, Seoul, 06591, Republic of Korea. Electronic address:

Objective: To introduce our novel technique for myometrial defect closure after adenomyomectomy.

Materials And Methods: A retrospective cohort study. A total of 40 patients with adenomyosis who visited our clinic between October 2012 and January 2018 were recruited. Read More

J Coll Physicians Surg Pak 2022 Mar;32(3):383-385

Department of Laboratory of Gynecologic Oncology, Fujian Provincial Maternity and Children's Hospital, Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China.

Submucosal uterine fibroids are usually associated with infertility and miscarriage. Hence, term pregnancies with large submucosal fibroids are rare in clinical practice. The management of fibroids during pregnancy remains controversial. Read More

J Minim Invasive Gynecol 2022 Jun 24;29(6):726-737. Epub 2022 Jan 24.

Department of Obstetrics, Gynecology and Reproductive Sciences (Dr. Levy), San Diego, California; Department of Obstetrics and Gynecology, George Washington University School of Medicine and Health Sciences (Dr. Levy), Washington, District of Columbia. Electronic address:

Study Objective: The objective of this study was to determine the efficacy, safety, and healthcare resource use of laparoscopic radiofrequency ablation (LAP-RFA) compared with myomectomy in patients with symptomatic uterine leiomyomas (ULs).

Design: This was a secondary analysis of the original postmarket randomized, multicenter, longitudinal, comparative TRUST (Treatment Results of Uterine Sparing Technologies) United States trial in patients with symptomatic ULs. After the procedure, subjects were followed over a 12-month period. Read More

Yonsei Med J 2022 Feb;63(2):179-186

Department of Obstetrics and Gynecology, Women's Cancer Center, Yonsei Cancer Center, Institute of Women's Life Medical Science, Yonsei University College of Medicine, Seoul, Korea.

Purpose: To report preliminary experience of single-port robotic surgery using the da Vinci SP surgical system in gynecologic tumors.

Materials And Methods: This was a retrospective study on 100 consecutive patients who underwent da Vinci SP single-port robotic surgery between November 2018 and January 2021. All procedures were performed by an experienced gynecologic surgeon using a single 2. Read More

PLoS One 2022 25;17(1):e0263058. Epub 2022 Jan 25.

Division of Interventional Radiology, Northwestern University, Chicago, IL, United States of America.

Background: Multidisciplinary collaboration has generally been shown to have positive effects on healthcare but can be difficult to facilitate. This study assessed the effects of a multidisciplinary fibroid clinic on practice patterns and clinician perceptions to better understand drivers of interspecialty collaboration.

Materials And Methods: Annual rates of hysterectomies, myomectomies, and uterine fibroid embolizations (UFEs) performed in an urban healthcare system were collected from 2012-2019. Read More

J Clin Med 2022 Jan 7;11(2). Epub 2022 Jan 7.

Department of Obstetrics and Gynecology, Wayne State University, Detroit, MI 48201, USA.

Adhesions frequently occur postoperatively, causing morbidity. In this noninterventional observational cohort study, we enrolled patients who presented for repeat abdominal surgery, after a history of previous abdominal myomectomy, from March 1998 to June 20210 at St. Vincent's Catholic Medical Centers. Read More

Fertil Steril 2022 02 31;117(2):456-457. Epub 2021 Dec 31.

Department of Obstetrics and Gynecology, Medical University of Vienna, Vienna, Austria.

Objective: To provide a video tutorial on myomectomy via mini-laparotomy in women with large uterine fibroids.

Design: Stepwise demonstration of the technique with narrated video footage.

Setting: Uterine fibroids represent the most common benign gynecologic disease, and myomectomy is a frequent reproductive surgery aiming to preserve or improve fertility. Read More

Front Surg 2021 9;8:788749. Epub 2021 Dec 9.

Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, National Clinical Research Center for Obstetric & Gynecologic Diseases, Beijing, China.

To investigate the clinical characteristics, treatment and prognosis of leiomyomatosis peritonealis disseminata (LPD) following laparoscopic surgery with uncontained morcellation and to summarize clinical features of iatrogenic LPD based on published literature together with our own experience. A cohort of 13 cases with iatrogenic LPD diagnosed and treated in Peking Union Medical College Hospital from 2011 to 2020 was reported focusing on clinical characteristics, treatment and prognosis. All the patients had a history of laparoscopic myomectomy with uncontained morcellation. Read More

J Obstet Gynaecol 2021 Dec 17:1-6. Epub 2021 Dec 17.

Obstetrics and Gynecologic Section, Department of Odontostomatologic and Specialized Clinical Sciences, Università Politecnica delle Marche, Ancona, Italy.

A retrospective study was conducted on patients subjected to laparoscopic myomectomy at our institution from January 2017 to December 2018 to identify predictive factors of blood loss. Two multiple regression models were run to predict intraoperative blood loss and haemoglobin drop. Predictors of an increased intraoperative blood loss and haemoglobin drop were the presence of three-four fibroids at ultrasound (+47 ml,  = . Read More

Eur J Obstet Gynecol Reprod Biol 2022 Jan 1;268:121-128. Epub 2021 Dec 1.

Endoscopic Training Center Antwerp (ETCA), Stuivenberg General Hospital, Ziekenhuis Netwerk Antwerpen (ZNA), Antwerp, Belgium; Università degli Studi dell'Insubria, Varese, Italy.

Objective: With this publication, the International Society for Gynecologic Endoscopy (ISGE) aims to provide the clinicians with the recommendations arising from the best evidence currently available on hysteroscopic myomectomy (HM).

Study Design: The ISGE Task Force for HM defined key clinical questions, which led the search of Medline/PubMed and the Cochrane Database. We selected and analyzed relevant English-language articles, published from January 2005 to June 2021, including original works, reviews and the guidelines previously published by the European Society for Gynecological Endoscopy (ESGE) and the American Association of Gynecologic Laparoscopists (AAGL), in which bibliographies were also checked in order to identify additional references, using the medical subject heading (MeSH) term "Uterine Myomectomy" (MeSH Unique ID: D063186) in combination with ''Myoma" (MeSH Unique ID: D009214) and ''Hysteroscopy" (MeSH Unique ID: D015907). Read More

Radiol Case Rep 2022 Feb 25;17(2):293-297. Epub 2021 Nov 25.

Department of Obstetrics and Gynecology, National Taiwan University Hospital, Taipei, Taiwan.

Leiomyomatosis peritonealis disseminata (LPD) is a rare clinical condition characterized by the development of multiple smooth muscle-like nodules in the peritoneal or abdominal cavity. Here, we report a case of a patient who was diagnosed with LPD after laparoscopic myomectomy with power morcellation. Growing evidence has shown that LPD might develop after using power morcellation for hysterectomy or myomectomy, and this can worsen the prognosis if the spreading tissue contains malignancies, such as leiomyosarcoma. Read More

Int J Environ Res Public Health 2021 11 19;18(22). Epub 2021 Nov 19.

Università Cattolica del Sacro Cuore, 00168 Rome, Italy.

Uterine myomas or uterine fibroids are the most common benign uterine masses affecting women. The management of large myoma during pregnancy is challenging, and surgical treatment is a possible option. We report nine cases of pregnant women affected by uterine masses larger than 10 cm, who underwent surgical treatment during the second trimester of pregnancy. Read More

Minerva Obstet Gynecol 2021 Nov 18. Epub 2021 Nov 18.

Service of Gynecology and Obstetrics, Department of Gynecology and Obstetrics, Ospedale Regionale di Lugano EOC, Lugano, Switzerland.

Introduction: Conventionally, laparoscopic surgery in gynecology requires multiple accesses in the abdominal cavity. Laparo-Endoscopic Single-Site surgery (LESS) is a more recent technique consisting in a laparoscopy in which the abdominal cavity is reached by a single umbilical incision. The aim of this systematic review is to summarize and comment the benefits and drawbacks in benign gynecological surgeries, including hysterectomy, myomectomy, and adnexal surgery, by LESS and conventional Multi-Port Laparoscopy (MPL), respectively. Read More

J Adv Pharm Res 2021 ;5(2):260-275

Department of Obstetrics and Gynecology, University of Chicago, Chicago, IL, 60637, USA.

Uterine fibroids (UFs) are the most prevalent gynecologic neoplasm, affecting 70-80% of women over their lifespan. Although UFs are benign they can become life-threatening and require invasive surgeries such as myomectomy and hysterectomy. Notwithstanding the significant negative influence UFs have on female reproductive health, very little is known about early events that initiate tumor development. Read More

Minim Invasive Ther Allied Technol 2022 Jun 3;31(5):698-703. Epub 2021 Nov 3.

Lebanese American University Medical Center - Rizk Hospital, Beirut, Lebanon.

Purpose: The purpose of this systematic review was to assess the characteristics of endobags present in the market, the weight of specimen removed, complications of the operations and time required for in-bag morcellation in women undergoing laparoscopic gynecologic surgeries.

Material And Methods: We performed a systematic review, including prospective and retrospective studies, with or without randomized allocation of the patients, using endobags in laparoscopic gynecologic surgeries. We extracted data about study design, type and price of bag used, type of surgical procedure, specimen weight, mean time for morcellation and for total surgical procedure, complications. Read More

Pain Physician 2021 11;24(7):E997-E1006

National and Kapodistrian University of Athens School of Health Sciences: Ethniko kai Kapodistriako Panepistemio Athenon, Athen, Greece.

Background: The management of acute postoperative pain remains challenging, and the search for adjuvants to reduce opioid use continues.

Objectives: We studied the effect of intravenous dexmedetomidine and lidocaine on postoperative pain, opioid consumption, and functional recovery.

Study Design: A randomized controlled trial was performed. Read More

Int J Surg Case Rep 2021 Nov 14;88:106507. Epub 2021 Oct 14.

Department B of Gynecologic Surgery, Tunis Maternity Center, Tunis Medical School, el Manar University, Tunisia.

Introduction And Importance: Abdominal wall endometriosis is a rare clinical condition associated with abdominal pain and psychologic disorders. It's pathophysiology remains unclear. Clinical history and imaging findings are necessary for the diagnosis. Read More

Medicine (Baltimore) 2021 Oct;100(40):e27441

Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.

Abstract: No studies have examined the issue of intraabdominal port-site adhesion following single-port access (SPA) laparoscopic surgeries. The purpose of the present study was to investigate the clinical effects of temperature-sensitive adhesion barrier solution in preventing periumbilical adhesion in SPA laparoscopy. This was a prospective, single-arm study in which patients were given GUARDIX-SGTM after SPA laparoscopic surgery for benign gynecologic diseases. Read More