50 results match your criteria Gynecologic Cryosurgery


Feasibility and safety of cryoablation on the porcine ureter using a new balloon cryoprobe.

Cryobiology 2020 10 21;96:130-136. Epub 2020 Jul 21.

Department of Gynecologic Oncology, The International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200030, China; Shanghai Municipal Key Clinical Specialty of Gynecologic Oncology, Shanghai, 200030, China; Shanghai Key Laboratory of Embryo Original Diseases Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200030, China. Electronic address:

Cryoablation, as a well-characterized technology, has multifarious clinical applications. But few are reported on ureteral endometriosis. Thus, we examined the feasibility and safety of cryotherapy with a novel balloon cryoprobe on ureter in a live porcine model. Read More

View Article and Full-Text PDF
October 2020

Cryoablation used in fertility-sparing treatment for early endometrial cancer: A pig model experiment using a new designed balloon cryoprobe.

Cryobiology 2020 06 17;94:89-94. Epub 2020 Apr 17.

Department of Gynecologic Oncology, The International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200030, China; Shanghai Municipal Key Clinical Specialty of Gynecologic Oncology, Shanghai, 200030, China; Shanghai Key Laboratory of Embryo Original Diseases Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200030, China. Electronic address:

Young patients with early endometrial cancer have a strong desire to retain reproductive function, which require us to develop a therapeutic method that can not only assure the complete resection of tumor but also retain the uterine integrity. In the present study, we proposed a fertility-sparing surgery option that combined hysteroscopic resection with cryoablation to achieve this goal. To verify the safety and effectiveness of cryoablation for local uterine wall, we designed the experiment in pig model using a novel cryoablation balloon probe. Read More

View Article and Full-Text PDF

Comparison of Cold-Knife Conization versus Loop Electrosurgical Excision for Cervical Adenocarcinoma In Situ (ACIS): A Systematic Review and Meta-Analysis.

PLoS One 2017 26;12(1):e0170587. Epub 2017 Jan 26.

Department of Gynecologic Oncology, Affiliated Tumor Hospital of Guangxi Medical University, Nanning, China.

Objective: The objective of this systematic review was to conduct a more comprehensive literature search and meta-analysis of original studies to evaluate the efficacy and safety of the loop electrosurgical excision procedure (LEEP) versus cold-knife conization (CKC) in conservative surgical treatment of cervical adenocarcinoma in situ (ACIS) for women who have not completed childbearing.

Methods: Systematic searches were conducted in the PUBMED, EMBASE, Cochrane, and China National Knowledge Infrastructure (CNKI) databases to identify all potential studies involving patients with ACIS treated with LEEP versus CKC published until December 2015.

Results: Eighteen retrospective studies were included in this systematic review. Read More

View Article and Full-Text PDF

[Cervical cryosurgery: thousand cases report].

Ginecol Obstet Mex 2014 Aug;82(8):518-22

Background: Treatments for cervical lesions through the years have been varied, from cauterization with chemicals, to the use of electrosurgery with diathermic loop, however the method to be chosen should be one that offers greater benefits and lower risks.

Objective: Present a well structured study protocol in patients presenting with cervical disease and offer treatment cryotherapy as ablative method of choice in this group of patients and returning this widely known process, but nevertheless had been relegated.

Material And Method: By an analytical and descriptive retrospective study and treatment of one thousand patients with cervical pathology in the course of 20 years, in which in addition to the drug treatment of individual patients, treatment was performed as ablative cryosurgery cervical is reported, having obtained very good results. Read More

View Article and Full-Text PDF

Clinical outcomes of cases with cervical dysplasia absent in cold knife conization specimens.

Asian Pac J Cancer Prev 2014 Jan;14(11):6693-6

Department of Gynecologic Oncology, Zekai Tahir Burak Women's Health Education and Research Hospital, Ankara, Turkey E-mail :

Background: Cold knife conization is a surgical procedure that allows both diagnosis and treatment of cervical lesions at the same time. It is mainly performed for indications of high-grade cervical intraepithelial neoplasia (CIN). In this study, we aimed to investigate the clinical outcome of cases without CIN in cold knife conization specimen, following a high-grade lesion (CIN2/3) in cervical biopsy. Read More

View Article and Full-Text PDF
January 2014

Long-term oncological and reproductive outcomes of fertility-sparing cytoreductive surgery in females aged 25 years and younger with malignant ovarian germ cell tumors.

J Obstet Gynaecol Res 2014 Mar 10;40(3):797-805. Epub 2013 Dec 10.

Department of Gynecologic Oncology, Tepecik Education and Research Hospital, Izmir, Turkey.

Aim: To evaluate the long-term oncological and reproductive outcomes of patients aged 25 years and younger who were treated by fertility-sparing cytoreductive surgery (FSCS) plus adjuvant chemotherapy (ACT) or observation alone for malignant ovarian germ cell tumors (MOGCT).

Methods: Records of 42 eligible female patients treated for MOGCT between 1 May 1995 and 31 December 2010 at two centers were analyzed retrospectively. A telephone questionnaire was performed to gather reproductive and menstrual history. Read More

View Article and Full-Text PDF

The relationship between previous treatment for cervical dysplasia and preterm delivery in twin gestations.

J Matern Fetal Neonatal Med 2014 May 23;27(8):821-4. Epub 2013 Sep 23.

Department of Gynecology and Obstetrics, Division of Maternal-Fetal Medicine, Johns Hopkins University School of Medicine , Baltimore, MD , USA .

Objective: To describe the impact of previous cervical surgery on preterm birth prior to 34 weeks in twins.

Methods: A retrospective review of twin pregnancies delivered between January 1998 and December 2005 at two institutions was performed. Women with a prior cold knife cone (CKC), loop electrosurgical excision procedure (LEEP), or ablative procedure were compared to a control group of women who had not undergone a previous treatment for cervical dysplasia. Read More

View Article and Full-Text PDF

Risk of residual disease and invasive carcinoma in women treated for adenocarcinoma in situ of the cervix.

Gynecol Oncol 2013 Jun 28;129(3):513-6. Epub 2013 Mar 28.

Department of Gynecologic Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.

Objective: Cervical adenocarcinoma in situ (AIS) is increasing in incidence among reproductive-age women. Cervical conization is an alternative to hysterectomy that allows future fertility, however reports regarding the risk of residual AIS and underlying adenocarcinoma are conflicting. The purpose of this study was to determine the outcomes of a large cohort of women treated for AIS. Read More

View Article and Full-Text PDF

Fertility-sparing treatment in younger women with adenocarcinoma in situ of the cervix.

Gynecol Oncol 2012 Jan 24;124(1):72-7. Epub 2011 Oct 24.

Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Brigham and Women's Hospital, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.

Objective: For women who have completed childbearing, the treatment of choice for adenocarcinoma in situ (ACIS) of the cervix is hysterectomy. In women who desire future fertility, however, conservative therapy is an acceptable alternative. In this study we compare the outcomes for young women who underwent loop conization or were treated with cold knife conization. Read More

View Article and Full-Text PDF
January 2012

[Study on high risk factors associated with positive margin of cervix conization in patient with cervical intraepithelial neoplasia].

Zhonghua Fu Chan Ke Za Zhi 2009 Mar;44(3):200-3

Department of Gynecologic Oncology, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou 310006, China.

Objective: To assess the high risk factors associated with the positive margin of conization in patients with cervical intraepithelial neoplasia (CIN).

Methods: From January 2000 to February 2008, 1699 consecutive patients with CIN undergoing conization was reviewed retrospectively in order to analyze the relationship between the positive margin of conization with clinical prognostic factors, such as patients age, disease grade, size of lesion, the procedure of excision and menopause. chi2 tests was used to compare the different frequencies of factors in groups of positive and negative margin conization, then seven factors with positive margin were processed into unconditional logistic regression analysis. Read More

View Article and Full-Text PDF

Global endometrial ablation devices.

Clin Obstet Gynecol 2008 Mar;51(1):167-75

Department of Obstetrics and Gynecology, University of Utah Health Sciences Center, Salt Lake City, Utah, USA.

Since 1997, the US Food and Drug Administration has approved 5 global endometrial ablation (GEA) devices for the minimally invasive treatment of idiopathic menorrhagia. These include a variety of modalities to ablate the endometrium, including thermal balloon, circulated hot fluid, cryotherapy, radiofrequency electrosurgery, and microwave energy. Level I evidence is available to support high subjective satisfaction rates regardless of GEA method. Read More

View Article and Full-Text PDF

Costs of colposcopy services and their impact on the incidence and mortality rate of cervical cancer in Canada.

J Low Genit Tract Dis 2005 Jul;9(3):160-6

Division of Gynecologic Oncology, Department of Obstertics and Gynecology, University of British Columbia, 805 W. 12th Avenue, Vancouver, B.C., V5Z 1M4 Canada.

Objective: Organized cervical cancer screening services consisting of conventional Papanicolaou cervical smears, colposcopy, and related treatment modalities are readily available in all provinces. The purpose of this report was to study the impact of colposcopy usage and costs on cervical cancer incidence and mortality rates in several Canadian provinces. Knowledge of such information is essential before newer technology such as liquid-based cytology and human papillomavirus testing is introduced or replaces the traditional systems used. Read More

View Article and Full-Text PDF

Directed laparoscopic cryomyolysis for symptomatic leiomyomata: one-year follow up.

J Minim Invasive Gynecol 2005 Jul-Aug;12(4):343-6

Department of Gynecology, Tor Vergata University of Rome, Italy.

Study Objective: To evaluate the long-term effectiveness of laparoscopic cryomyolysis as a minimally invasive technique for the treatment of symptomatic uterine myomas in menstruating women.

Design: Open, one-arm pilot study (Canadian Task Force classification II).

Setting: University-affiliated public hospital. Read More

View Article and Full-Text PDF
November 2005

Recent trends in laproscopic myomectomy.

J Ayub Med Coll Abbottabad 2004 Jan-Mar;16(1):58-63

Combined Military Hospital, Peshawer.

Recently there is an increasing trend for minimal access surgery (MAS) for treatment of uterine myomas. Laparoscopic myomectomy has provided minimal invasive alternative to laparotomy for subserosa and intramural myomas. It is associated with faster postoperative recovery and potentially less postoperative adhesions. Read More

View Article and Full-Text PDF

Human papillomavirus infections: diagnosis, treatment, and hope for a vaccine.

Authors:
Kevin A Ault

Obstet Gynecol Clin North Am 2003 Dec;30(4):809-17

Department of Obstetrics and Gynecology, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, IA 52242, USA.

HPV infections are common, with millions of Americans infected. Common gynecologic manifestations of HPV infection include genital warts and cervical neoplasia. The CDC recently issued guidelines for the treatment of genital warts. Read More

View Article and Full-Text PDF
December 2003

Frozen section evaluation of cervical cold knife cone specimens is accurate in the diagnosis of microinvasive squamous cell carcinoma.

Gynecol Oncol 2003 Nov;91(2):280-4

Division of Gynecologic Oncology, Thomas Jefferson University, Philadelphia, PA 19107, USA.

Objectives: The purpose of this study was to determine the accuracy of frozen section evaluation of cervical cold knife cone (CKC) specimens in the diagnosis of microinvasive squamous cell carcinoma (SCC).

Methods: Using ICD-9 codes for invasive and microinvasive carcinoma of the cervix, a medical record from 1986 to 1998 identified 110 potential study subjects. Society of Gynecologic Oncologists criteria including depth of invasion < or =3 mm and absence of lymph-vascular space involvement were utilized for the diagnosis of microinvasion. Read More

View Article and Full-Text PDF
November 2003

[Sparing therapy of aged patients with cancer of the endometrium, uterine cervix, and vulva].

Lik Sprava 2002 (7):54-6

Outlined in the article are main principles of organ-preserving and sparing treatment of aged female patients with carcinoma of the body of the womb and vulva. Indications are determined for surgical management of the above medical problem in elderly women. Revelant treatment options are described. Read More

View Article and Full-Text PDF

[Treatment of precancerous changes of the uterine cervix].

Authors:
V Zlatkov

Akush Ginekol (Sofiia) 2002 ;41(6):48-52

The aim of the present review is to view the possibilities for the treatment of the precancer lesions of the uterine cervix, on the basis of the modern tendencies in the gynecological practice. The description and criteria for the applicability of the actively observation, different destructive--chemical, thermo-, cryo-, electro- and laser ablation, as well as excisional methods--classical, surgical, laser and LEEP/LLETZ conization were discussed. The advantages and disadvantages of each method were pointed out. Read More

View Article and Full-Text PDF

Advances in endometrial ablation.

Obstet Gynecol Surv 2002 Dec;57(12):789-802

Department of Obstetrics and Gynecology, Good Samaritan Regional Medical Center, Phoenix, Arizona 85006, USA.

Unlabelled: The evolution of the surgical treatment of dysfunctional uterine bleeding has resulted in the design and manufacture of instrumentation that is minimally invasive, has a low risk profile, and is technically simple to operate. Whereas hysterectomy was the only definitive surgical option before 1981, operative hysteroscopy with transcervical resection of the endometrium and rollerball ablation of the endometrium gained favor in the mid-1980s and 1990s. During the past 10 years, devices dedicated entirely to the ablation (or destruction) of the endometrium have been designed, modeled, tested, and approved for clinical use in the United States. Read More

View Article and Full-Text PDF
December 2002

Cold knife conization vs. LEEP. Are they the same procedure?

J Reprod Med 2002 Jan;47(1):33-5

Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Medical College of Ohio, Richard D. Ruppert Health Center, Toledo, OH 43614-5809, USA.

Objective: To prospectively evaluate the amount of tissue removed at loop electrosurgical excision procedure (LEEP) vs. cold knife conization.

Study Design: Forty consecutive LEEP or cold knife conization specimens were prospectively measured and weighed by a single pathology technician. Read More

View Article and Full-Text PDF
January 2002

Minimally invasive management of hepatic metastases.

Semin Laparosc Surg 2000 Jun;7(2):118-28

Brown University School of Medicine, Providence, RI 02905, USA.

The introduction of laparoscopy for diagnosis of abdominal tumors has also allowed for the destruction of hepatic metastases by cryotherapy and radiofrequency ablation. The advantage of laparoscopically based therapy over the percutaneous treatment is the benefit of finding additional lesions that preoperative studies may not have detected. The results from available data in patients with metastatic colorectal carcinoma suggest an improvement in survival. Read More

View Article and Full-Text PDF

Conservative management of adenocarcinoma in situ of the cervix.

Gynecol Oncol 2000 Oct;79(1):6-10

Division of Gynecologic Oncology, Division of Women's and Perinatal Pathology, Brigham and Women's Hospital, 75 Francis Street, Boston, Massachusetts 02115, USA.

Objective: The purpose of this study was to determine the method of treatment and outcome of women with cervical adenocarcinoma in situ (AIS).

Methods: Following institutional review board approval, all women diagnosed with cervical AIS from 1987 to 1999 were identified. Data were retrospectively collected by record review and correspondence with medical providers. Read More

View Article and Full-Text PDF
October 2000

Cryotherapy: evidence-based interventions and informed consent.

Authors:
C J Dunton

J Fam Pract 2000 Aug;49(8):707-8

Thomas Jefferson University, Division of Gynecologic Oncology, Philadelphia, PA 19107, USA.

View Article and Full-Text PDF

Global endometrial ablation technologies.

Obstet Gynecol Clin North Am 2000 Jun;27(2):385-96, viii

Department of Obstetrics and Gynecology, University of Arizona, School of Medicine, Phoenix Baptist Hospital, USA.

The value of extirpative surgery for excessive uterine bleeding is questionable. A number of technologies have been developed that destroy the endometrial lining while preserving the uterus. This article compares and contrasts multiple modalities of global endometrial ablation technology. Read More

View Article and Full-Text PDF

Colposcopy, cervicography, speculoscopy and endoscopy. International Academy of Cytology Task Force summary. Diagnostic Cytology Towards the 21st Century: An International Expert Conference and Tutorial.

Acta Cytol 1998 Jan-Feb;42(1):33-49

Issues: The colposcope was developed in 1925 and is well established in clinical gynecologic practice for defining and delineating cytologically detected lesions mainly of the cervix but also the vagina and vulva. Additionally, various endoscopic procedures in gastroenterology, pulmonary and urologic lesions enhance the cytologic detection and histologic verification of precancerous and cancerous lesions. The cost-effectiveness of all these devices and their applicability, particularly in countries with a limited health budget, is a major issue. Read More

View Article and Full-Text PDF

Cryotherapy.

Authors:
K D Hatch

Baillieres Clin Obstet Gynaecol 1995 Mar;9(1):133-43

Division of Gynecologic Oncology, University of Arizona, Tucson 85724, USA.

Cryotherapy is as effective as any other therapy for CIN 1 and CIN 2. It can be performed with a minimum of side-effects and long-term sequelae. It is more cost-efficient than other methods since the equipment is inexpensive and it requires little technical training. Read More

View Article and Full-Text PDF

Small FIGO stage IB cervical cancer.

Gynecol Oncol 1994 Dec;55(3 Pt 1):427-32

Department of Obstetrics and Gynecology, University of Graz, Austria.

The International Federation of Gynecology and Obstetrics (FIGO) currently defines stage IA cervical cancer as lesions invading up to 5 mm into the stroma and with no more than 7 mm width; vascular invasion does not affect the stage assignment. The Society of Gynecologic Oncology (SGO) definition of stage IA is more restrictive with regard to depth of invasion but ignores width. We reviewed 69 patients with lesions exceeding the FIGO definition of stage IA treated between 1958 and 1991; 46 patients also exceeded the SGO criteria for stage IA. Read More

View Article and Full-Text PDF
December 1994

Use of the Cytobrush for cervical sampling after cryotherapy.

Acta Cytol 1991 Jan-Feb;35(1):79-80

Department of Obstetrics and Gynecology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612-9497.

The presence of endocervical cells in routine gynecologic smears (prepared from spatula and cotton swab samples) and Cytobrush smears was analyzed in 52 patients with a history of prior cryotherapy. These cases represented 11% of the 491 women evaluated using both techniques between August 1, 1987, and January 31, 1990. The routine smear contained endocervical cells in 25 (48%) of the 52 cases while the Cytobrush smear contained endocervical cells in 49 (94%) of the cases. Read More

View Article and Full-Text PDF

Pediatric bowenoid papulosis: risks and management.

Pediatr Dermatol 1989 Dec;6(4):303-5

Department of Dermatology, Mount Sinai Medical Center, Miami Beach, Florida 33140.

A 34-month-old Haitian girl had a six-month history of asymptomatic vulvar papules. Histologic features and DNA probe studies were diagnostic of bowenoid papulosis. Resolution of the lesions was enhanced by cryotherapy. Read More

View Article and Full-Text PDF
December 1989

[Approaches to treatment for gynecologic malignancies--particularly on hyperthermic treatment].

Authors:
K Sekiba

Nihon Sanka Fujinka Gakkai Zasshi 1989 Aug;41(8):937-41

Department of Obstetrics and Gynecology, Okayama University Medical School.

Diagnosis and treatment at the early stage are bases of therapy for cancer. Great efforts have been made from this policy also in treatment of cervical cancer most frequently encountered in gynecology. Recent progress of cytodiagnosis and prevalence of mass screening enable us to more frequently detect intraepithelial lesions, such as dysplasia, CIS, and early cancer at Stage Ia, and are about to achieve the initial object with 5-years surgical cure rate close to 100%. Read More

View Article and Full-Text PDF