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Arq Neuropsiquiatr 2020 May 1;78(5):290-300. Epub 2020 Jun 1.

Internal Medicine Department, Hospital de Clínicas, Universidade Federal do Paraná, Curitiba, PR, Brazil.

Background: As the COVID-19 pandemic unfolds worldwide, different forms of reports have described its neurologic manifestations.

Objective: To review the literature on neurological complications of SARS-CoV-2 infection.

Methods: Literature search performed following systematic reviews guidelines, using specific keywords based on the COVID-19 neurological complications described up to May 10th, 2020. Read More

Sci Rep 2020 Jun 2;10(1):8929. Epub 2020 Jun 2.

Bioinformatics Program, Taiwan International Graduate Program, Institute of Information Science, Academia Sinica, Taipei, 11529, Taiwan.

Zika virus (ZIKV) of the flaviviridae family, is the cause of emerging infections characterized by fever, Guillain-Barré syndrome (GBS) in adults and microcephaly in newborns. There exists an urgent unmet clinical need for anti-ZIKV drugs for the treatment of infected individuals. In the current work, we aimed at the promising virus drug target, ZIKV NS3 protease and constructed a Pharmacophore Anchor (PA) model for the active site. Read More

Pract Neurol 2020 Jun 2. Epub 2020 Jun 2.

Department of Neurology, Royal Preston Hospital, Lancashire Teaching Hospitals NHF Foundation Trust, Preston PR2 9HT, UK.

Vaccines (Basel) 2020 May 31;8(2). Epub 2020 May 31.

School of Veterinary Medicine and Biomedical Sciences, University of Nebraska-Lincoln, Lincoln, NE 68583, USA.

The recently emerged Zika virus (ZIKV) spread to the Americas, causing a spectrum of congenital diseases including microcephaly in newborn and Guillain-Barré syndrome (GBS) in adults. The unprecedented nature of the epidemic and serious diseases associated with the viral infections prompted the global research community to understand the immunopathogenic mechanisms of the virus and rapidly develop safe and efficacious vaccines. This has led to a number of ZIKV vaccine candidates that have shown significant promise in human clinical trials. Read More

Curr Pharm Biotechnol 2020 Jun 2. Epub 2020 Jun 2.

Department of Virology and Experimental Therapy, Aggeu Magalhães Institute, Oswaldo Cruz Foundation/FIOCRUZ, Recif. Brazil.

Background: Zika virus is an emerging arbovirus of global importance. ZIKV infection is associated with a range of neurological complications such as the Congenital Zika Syndrome and Guillain Barré Syndrome. Despite the magnitude of recent outbreaks, there is no specific therapy to prevent or to alleviate disease pathology. Read More

Ann Clin Transl Neurol 2020 Jun 2. Epub 2020 Jun 2.

Laboratory of Gut-Brain Signaling, Laboratory Sciences and Services Division (LSSD), icddr,b, Dhaka, 1212, Bangladesh.

Objective: Guillain-Barré syndrome (GBS) is a rare, life-threatening disorder of the peripheral nervous system. Immunoglobulin G Fc-gamma receptors (FcγRs) mediate and regulate diverse effector functions and are involved in the pathogenesis of GBS. We investigated whether the FcγR polymorphisms FcγRIIa H/R131 (rs1801274), FcγRIIIa V/F158 (rs396991), and FcγRIIIb NA1/NA2, and their haplotype patterns affect the affinity of IgG-FcγR interactivity and influence GBS susceptibility and severity. Read More

Neurol Sci 2020 Jun 1. Epub 2020 Jun 1.

Department of Midwifery, Faculty of Medicine, Social Development and Health Promotion Research Center, Gonabad University of Medical Sciences, Gonabad, Iran.

Results: Various neurological manifestations have been reported in the literature associated with COVID-19, which in the current study are classified into Central Nervous System (CNS) related manifestations including headache, dizziness, impaired consciousness, acute cerebrovascular disease, epilepsy, and Peripheral Nervous System (PNS) related manifestations such as hyposmia/anosmia, hypogeusia/ageusia, muscle pain, and Guillain-Barre syndrome.

Conclusion: During the current context of COVID-19 pandemic, physicians should be aware of wide spectrum of neurological COVID-19 sign and symptoms for early diagnosis and isolation of patients. In this regard, COVID-19 has been associated with many neurological manifestations such as confusion, anosmia, and ageusia. Read More

Theranostics 2020 16;10(14):6430-6447. Epub 2020 May 16.

CAS Key Laboratory of Special Pathogens and Biosafety, Center for Emerging Infectious Diseases, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, China.

: Zika virus (ZIKV) is a pathogenic virus known to cause a wide range of congenital abnormalities, including microcephaly, Guillain-Barre syndrome, meningoencephalitis, and other neurological complications, in humans. This study investigated the noninvasive detection of ZIKV infection , which is necessary for elucidating the virus's mechanisms of viral replication and pathogenesis, as well as to accelerate the development of anti-ZIKV therapeutic strategies. : In this study, a recombinant ZIKV harbouring Nluc gene (ZIKV-Nluc) was designed, recovered, and purified. Read More

Neurology 2020 Jun 1. Epub 2020 Jun 1.

Department of Neurology. Complejo Hospitalario Universitario de Albacete, Albacete, Castilla-La Mancha, Spain.

Objective: The coronavirus disease 2019 (COVID-19) has spread worldwide since December 2019. Neurological symptoms have been reported as part of the clinical spectrum of the disease. We aim to determine whether neurological manifestations are common in hospitalized COVID-19 patients and to describe their main characteristics. Read More

Eur J Neurol 2020 Jun 1. Epub 2020 Jun 1.

Division of Neurology, Department of Clinical Neuroscience, Geneva University Hospitals and University of Geneva, Faculty of Medicine, Geneva, Switzerland.

The entire world has been experiencing the outbreak of a novel infectious agent known as severe acute respiratory syndrome corona virus 2 (SARS-CoV-2), which is responsible for the coronavirus disease 19 (COVID-19) . Life-threatening complications described in SARS-CoV-2 infected patients include acute respiratory distress syndrome, acute kidney failure and cardiac injury . Nonetheless, only few neurological complications have been described so far . Read More

Virol Sin 2020 May 29. Epub 2020 May 29.

CAS Key Laboratory of Special Pathogens and Biosafety, Center for Emerging Infectious Diseases, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, 430071, China.

Zika virus (ZIKV) is emerging as a significant pathogen worldwide and may cause severe neurological disorders such as fetal microcephaly and Guillain-Barre syndrome. No drug or listed vaccines are currently available for preventing ZIKV infection. As a major target of neutralizing, ZIKV envelop (E) protein usually used for vaccine development. Read More

J Mol Neurosci 2020 May 29. Epub 2020 May 29.

Neurophysiology Research Center, Hamadan University of Medical Sciences, Hamadan, Iran.

Immune-mediated neuropathies include some specific types such as acute and chronic inflammatory demyelinating polyneuropathy (AIDP and CIDP). Previous studies have demonstrated abnormal cellular or humoral immune responses in these conditions. Although aberrant regulation of several cytokines have been reported in AIDP and CIDP, the significance of interleukin 19 (IL-19) in these conditions have not been elucidated yet. Read More

Hematol Oncol Stem Cell Ther 2020 May 20. Epub 2020 May 20.

Roswell Park Comprehensive Cancer Centre, Buffalo, NY, USA. Electronic address:

Paraneoplastic neurological syndromes are a rare manifestation of non-Hodgkin lymphoma and can make treatment of these patients more challenging. We report the case of a 67-year-old man with high grade diffuse large B-cell lymphoma who presented with severe paraneoplastic Guillain-Barré syndrome. He was treated with intravenous immunoglobulin therapy and definitive chemoimmunotherapy, and achieved a full neurological recovery. Read More

Arch Argent Pediatr 2020 Jun;118(3):e333-e337

Sala 3ª de Internación de Clínica Pediátrica del Hospital Interzonal de Agudos Especializado en Pediatría Superiora Sor María Ludovica de La Plata.

Miller-Fisher syndrome and Bickerstaff brainstem encephalitis, among others, constitute the anti-GQ1b syndrome, with a common immune pathophysiologic pathway characterized by the presence of anti-GQ1b antibodies, which react against the different nervous system GQ1b sites according to their different accessibility. The Miller-Fisher syndrome has a prevalence of 0.09 cases per 100 000 people-year but there are not epidemiological studies about Bickerstaff brainstem encephalitis, that it seems to be less frequent. Read More

Can J Neurol Sci 2020 May 29:1-10. Epub 2020 May 29.

Neurol Sci 2020 May 28. Epub 2020 May 28.

Neurology Unit, Galliera Hospital, Via Mura delle Cappuccine 14, 16128, Genova, Italy.

Cureus 2020 Apr 25;12(4):e7823. Epub 2020 Apr 25.

Neurology, Marcus Neuroscience Institute, Boca Raton Regional Hospital, Boca Raton, USA.

Guillain-Barre syndrome (GBS) is an acute paralytic neuropathy. Limited reports of GBS caused by tick-borne pathogens exist. Lyme disease is a tick-borne infectious disease that is commonly caused by Borrelia burgdorferi. Read More

AJNR Am J Neuroradiol 2020 May 28. Epub 2020 May 28.

From the Department of Radiology, Weill Cornell Medical Center/New York Presbyterian Hospital, New York, New York.

Miller Fisher syndrome, also known as Miller Fisher variant of Guillain-Barré syndrome, is an acute peripheral neuropathy that can develop after exposure to various viral, bacterial, and fungal pathogens. It is characterized by a triad of ophthalmoplegia, ataxia, and areflexia. Miller Fisher syndrome has recently been described in the clinical setting of the novel coronavirus disease 2019 (COVID-19) without accompanying imaging. Read More

J Neurol Sci 2020 May 7;414:116884. Epub 2020 May 7.

Pakistan International Neuroscience Society, Neurology, Aga Khan University, Karachi, Pakistan.

A comprehensive review of the neurological disorders reported during the current COVID-19 pandemic demonstrates that infection with SARS-CoV-2 affects the central nervous system (CNS), the peripheral nervous system (PNS) and the muscle. CNS manifestations include: headache and decreased responsiveness considered initial indicators of potential neurological involvement; anosmia, hyposmia, hypogeusia, and dysgeusia are frequent early symptoms of coronavirus infection. Respiratory failure, the lethal manifestation of COVID-19, responsible for 264,679 deaths worldwide, is probably neurogenic in origin and may result from the viral invasion of cranial nerve I, progressing into rhinencephalon and brainstem respiratory centers. Read More

Neurol Neuroimmunol Neuroinflamm 2020 09 27;7(5). Epub 2020 May 27.

From the Service de Neurologie (K.B., P.V., L.K., J.-B.C., J.S.), Hôpitaux Universitaires de Strasbourg; Service de Neurologie (M.M.), Centre Hospitalo-Universitaire de Grenoble Alpes, La Tronche; Service de Neuroradiologie (S.B.), Hôpitaux Universitaires de Strasbourg; Institut de Biologie Structurale (IBS) (B.N., P.M.), Université de Grenoble Alpes, CEA, CNRS; Laboratoire de virologie (B.N., P.M.), Centre Hospitalo-Universitaire de Grenoble Alpes, La Tronche; Service d'Accueil des Urgences (F.B.), Hôpitaux Universitaires de Strasbourg; and Service de Réanimation Polyvalente Chirurgicale (A.G.), Centre Hospitalo-Universitaire de Grenoble Alpes, La Tronche, France.

BMC Neurol 2020 May 27;20(1):214. Epub 2020 May 27.

Division of Neurology, Department of Internal Medicine IV, Osaka Medical College, 2-7 Daigaku-machi, Takatsuki, Osaka, 569-8686, Japan.

Background: It is not well defined whether Guillain-Barré syndrome (GBS) patients with elevated serum creatine kinase (CK) levels have characteristic clinical features and are related to the subgroups of GBS.

Methods: We retrospectively studied 51 consecutive patients with GBS, who visited our hospital, and compared clinical, laboratory and electrophysiological findings between patients with and without elevated CK levels.

Results: Of 51 patients, 14 patients (27%) showed an elevation of serum CK levels. Read More

J Neurol 2020 May 26. Epub 2020 May 26.

Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Avenue, Wuhan, Hubei, People's Republic of China.

Coronavirus disease 2019 (COVID-19), a disease caused by the novel betacoronavirus (SARS-CoV-2), has become a global pandemic threat. The potential involvement of COVID-19 in central nervous system (CNS) has attracted considerable attention due to neurological manifestations presented throughout the disease process. In addition, SARS-CoV-2 is structurally similar to SARS-CoV, and both bind to the angiotensin-converting enzyme 2 (ACE2) receptor to enter human cells. Read More

J Neurol 2020 May 26. Epub 2020 May 26.

Neurology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.

J Clin Neuromuscul Dis 2020 06;21(4):240-242

Department of Neurology and Neuroscience Institute, Allegheny General Hospital, Allegheny Health Network, Pittsburgh, PA.

J Clin Neuromuscul Dis 2020 Jun;21(4):225-229

Department of Neurology, NewYork-Presbyterian Hospital, Weill Cornell Medical College, Brain and Mind Research Institute, New York, NY.

Bickerstaff brainstem encephalitis, widely considered to be associated with Miller Fisher and Guillain-Barré syndromes, is a rare disease state defined by the triad of ophthalmoplegia, ataxia, and decreased consciousness. The presence of central nervous system involvement, commonly in the form of impaired arousal, solidifies it as a unique entity. We present a case of this rare syndrome after autologous stem cell transplant. Read More

Farm Hosp 2020 Mar 1;44(2):77-78. Epub 2020 Mar 1.

Pharmacy Service, Hospital Santa Bárbara, Puertollano, Ciudad Real. Spain..

J Neuroimmune Pharmacol 2020 06 23;15(2):167-173. Epub 2020 May 23.

Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, NE, 68198, USA.

A number of neurological disease complications have been seen following infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). While most person with COVID-19 respiratory disease demonstrate headache, nausea and vomiting, up to 40% present also experience dizziness, confusion, cerebrovascular disease, muscle pain, ataxia and seizures. Loss of taste and smell, defects in visual acuity and pain occur in parallel. Read More

J Neurol Sci 2020 May 16;415:116908. Epub 2020 May 16.

Laboratory of Gut-Brain Signaling, Laboratory Sciences and Services Division (LSSD), icddr,b, Dhaka 1212, Bangladesh. Electronic address:

Guillain-Barré syndrome (GBS) is an immune-mediated neurological disorder with a multifaceted nature. Infectious agents and immune-response genetic host factors may contribute to the development of GBS. The matrix metalloproteinase-9 (MMP-9), an enzyme is upregulated by pro-inflammatory cytokines and might play an important role in the pathogenesis of GBS. Read More

Brain Behav Immun 2020 May 20. Epub 2020 May 20.

Department of Neurology, King George Medical University, Lucknow, UP, India.

J Infect 2020 May 21. Epub 2020 May 21.

Nuffield Department of Primary Health Care Sciences, University of Oxford, Oxford, OX2 6GG, United Kingdom; NIHR Health Protection Research Unit, Gastrointestinal Infections Theme, University of Oxford, Oxford, United Kingdom.

Background: Reactive arthritis, irritable bowel syndrome (IBS), Guillain-Barré syndrome, ulcerative colitis, and Crohn's disease may be sequelae of Campylobacter or non-typhoidal Salmonella (NTS) infections. Proton pump inhibitors (PPI) and antibiotics may increase the risk of gastrointestinal infections (GII); however, their impact on sequelae onset is unclear. We investigated the incidence of sequelae, their association with antibiotics and PPI prescription, and assessed the economic impact on the NHS. Read More

Muscle Nerve 2020 May 23. Epub 2020 May 23.

Department of Neurology, Veterans Affairs Pittsburgh Healthcare System, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.

Medicine (Baltimore) 2020 May;99(20):e20227

Department of Neurology, Third Central Hospital of Tianjin.

Rationale: Although distal nerves located at sites prone to compression are susceptible to autoimmune attack, Guillain-Barre' syndrome (GBS) with exclusive hand muscle involvement is rarely found in clinics. All reported patients presented with a special variant - finger extensor weakness, especially claw hand caused by predominant ulnar extensor involvement. Similar to typical GBS, these patients showed bilateral symmetric onset with rapid clinical progression. Read More

J Pediatr Neurosci 2020 Jan-Mar;15(1):60-62. Epub 2020 Mar 19.

Department of Paediatrics, Grant Government Medical College and Sir Jamsetjee Jejeebhoy Group of Hospitals, Mumbai, Maharashtra, India.

Miller Fisher syndrome (MFS), a rare form of Guillain-Barré Syndrome, presents with the classical triad of ophthalmoplegia, areflexia, and ataxia. We describe the case of a 7-year-old boy who presented with diplopia, speech difficulty, dysphagia, gait disturbance, and difficulty in eyeball movements since 5 days. On examination, the child was having ataxia, areflexia, ophthalmoplegia, drooling of saliva, dysphonia, and absent gag reflex. Read More

Eur Rev Med Pharmacol Sci 2020 05;24(9):5178-5179

Department of Human Physiology and Pharmacology, "Sapienza" University of Rome, Rome, Italy.

J Neurol 2020 May 19. Epub 2020 May 19.

Clinical Neurology Unit, Santa Maria della Misericordia University Hospital, Udine, Italy.

Clin Pract Cases Emerg Med 2020 May 23;4(2):150-153. Epub 2020 Apr 23.

Brooke Army Medical Center, Department of Emergency Medicine, Fort Sam Houston, Texas.

Introduction: Facial diplegia, a rare variant of Guillain-Barré syndrome (GBS), is a challenging diagnosis to make in the emergency department due to its resemblance to neurologic Lyme disease.

Case Report: We present a case of a 27-year-old previously healthy man who presented with bilateral facial paralysis.

Discussion: Despite the variance in presentation, the recommended standard of practice for diagnostics (cerebrospinal fluid albumin-cytological dissociation) and disposition (admission for observation, intravenous immunoglobulin, and serial negative inspiratory force) of facial diplegia are the same as for other presentations of GBS. Read More

Am J Emerg Med 2020 May 16. Epub 2020 May 16.

Department of Emergency Medicine, Rush University Medical Center, Chicago, IL, United States of America.

Background: Much of the focus regarding the global pandemic of coronavirus disease of 2019 (COVID-19) has been on the cardiovascular, pulmonary, and hematologic complications. However, neurologic complications have arisen as an increasingly recognized area of morbidity and mortality.

Objective: This brief report summarizes the neurologic complications associated with COVID-19 with an emphasis on the emergency medicine clinician. Read More

Clin Neurophysiol 2020 07 11;131(7):1652-1654. Epub 2020 May 11.

Service de Neurologie, APHP, Hôpital Avicenne, Hôpitaux Universitaires de Paris - Seine Saint Denis, Sorbonne Paris Nord, Bobigny, France; Dynamics and Pathophysiology of Neuronal Networks Team, Center for Interdisciplinary Research in Biology, Collège de France, CNRS UMR7241/INSERM U1050, MemoLife Labex, 75005 Paris, France. Electronic address:

Ann Indian Acad Neurol 2020 Apr 21;23(Suppl 1):S40-S42. Epub 2020 Apr 21.

Dean, Bombay Hospital Institute of Medical Sciences, Mumbai, Maharashtra, India.

COVID-19 pandemic is ongoing and information on the neurological aspects of this viral infection is being gathered. Neuromuscular manifestations have been reported uncommonly in these early stages of the analysis. This manuscript studies the available information on the neuromuscular manifestations of COVID-19. Read More

Rev Neurol (Paris) 2020 May 15. Epub 2020 May 15.

Department of Neurology, University Hospital of Saint-Etienne, France.

J Crohns Colitis 2020 May 17. Epub 2020 May 17.

Department of Gastroenterology, University of São Paulo School of Medicine, São Paulo, SP, BR.

Eur J Neurol 2020 May 16. Epub 2020 May 16.

Department of Neurology, 4Brain, Gent University Hospital, Gent, Belgium.

Introduction: Infections with coronaviruses are not always confined to the respiratory tract and various neurological manifestations have been reported. The aim of this study was to perform a review to describe neurological manifestations in patients with COVID-19 and possible neuro-invasive mechanisms of Sars-CoV-2.

Methods: Pubmed, WebOfScience and Covid-dedicated databases were searched for the combination of COVID-19 terminology and neurology terminology up to May 10 2020. Read More

Clin Med (Lond) 2020 May;20(3):e12-e14

Aster Medcity, Kochi, India.

We present the case of a man who presented with severe left lower back pain radiating to the anterior aspect of left thigh. He also had fever and headache. Due to the exquisite tenderness along the inguinal region, the possibility of a psoas abscess was considered. Read More

Dermatol Ther 2020 May 15:e13591. Epub 2020 May 15.

Amity Institute of Pharmacy, Amity University Uttar Pradesh, Noida, Uttar Pradesh, India.

During the last few months, the whole humanity is experiencing largest and most severe sudden influx of COVID-19 outbreak caused by the novel coronavirus (CoV) originated from Wuhan, China. According to the WHO reports, total 3 862 676 positive cases and 265 961 deaths have been recorded worldwide due to COVID-19 infection as of May 9, 2020. CoVs are a large family of viruses (enveloped, single-stranded RNA viruses), which includes severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome-related coronavirus (MERS-CoV). Read More

Acta Neurol Scand 2020 May 15. Epub 2020 May 15.

Department of Cardiothoracic Surgery, Liverpool Heart and Chest, Liverpool, UK.

The novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was first identified in December of 2019 in the city of Wuhan, China. Since the outbreak, various reports detail its symptoms and outcomes, primarily focusing on respiratory complications. However, reports are emerging of the virus' effects systemically, including that of the nervous system. Read More

Mediterr J Rheumatol 2020 Mar 31;31(1):10-18. Epub 2020 Mar 31.

Aix Marseille Université, Institut de Neurosciences de la Timone, Medicine Faculty, Marseille, France.

Peripheral immune-mediated polyneuropathies (IMPN) are a diverse group of rare neurological illnesses characterized by nerve damage. Leading morphological features are mostly nerve fibre demyelination or combination of axonal damage and demyelination. There has been remarkable progress in the clinical and electrophysiological categorization of acute (fulminant, life-threatening) and chronic (progressive/remitting-relapsing) immune-mediated neuropathies recently. Read More

J Clin Neurosci 2020 May 14. Epub 2020 May 14.

Medical resident at the Department of Medical Oncology, Hospital General Universitario Gregorio Marañón, Madrid, Spain.

We present a case of facial diplegia after 10 days of SARS-CoV-2 confirmed infection symptoms in a 61 year old patient without prior clinically relevant background. There are few known cases of Guillain-Barré Syndrome (GBS) related to SARS-CoV-2 infection; we propose this case as a rare variant of GBS in COVID-19 infection context, due to Its chronology, clinical manifestations and cerebrospinal fluid (CSF) findings. Read More

Rev Neurol (Paris) 2020 May 14. Epub 2020 May 14.

Honorary professor, Dr DY Patil University, Pune, India.

Neurol Sci 2020 May 12. Epub 2020 May 12.

Neurology Unit, Rovereto Hospital, Azienda Provinciale per i Servizi Sanitari (APSS) di Trento, Trento, Italy.

Guillain-Barré syndrome (GBS) is an acute polyradiculoneuropathy associated with dysimmune processes, often related to a previous infectious exposure. During Italian severe acute respiratory syndrome coronavirus-2 outbreak, a woman presented with a rapidly progressive flaccid paralysis with unilateral facial neuropathy after a few days of mild respiratory symptoms. Coronavirus was detected by nasopharyngeal swab, but there was no evidence of its presence in her cerebrospinal fluid, which confirmed the typical albumin-cytological dissociation of GBS, along with consistent neurophysiological data. Read More

Viruses 2020 May 9;12(5). Epub 2020 May 9.

MRC-University of Glasgow Centre for Virus Research, Glasgow G61 1QH, UK.

Zika virus (ZIKV; Flaviviridae) is a mosquito-borne flavivirus shown to cause fetal abnormalities collectively known as congenital Zika syndrome and Guillain-Barré syndrome in recent outbreaks. Currently, there is no specific treatment or vaccine available, and more effort is needed to identify cellular factors in the viral life cycle. Here, we investigated interactors of ZIKV envelope (E) protein by combining protein pull-down with mass spectrometry. Read More