248 results match your criteria Granulomatous Prostatitis


Fungal prostatitis due to endemic mycoses and Cryptococcus: A multicenter case series.

Prostate 2020 Jun 22. Epub 2020 Jun 22.

Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, Maryland.

Background: Fungal prostatitis is exceedingly rare with mostly case reports.

Methods: Electronic medical records at three medical centers were searched for cases of fungal prostatitis due to endemic mycoses and Cryptococcus over the preceding 10 years.

Results: Seven cases were identified from 105 600 prostate biopsies within the Southern California Permanente Medical Group for an incidence of 0. Read More

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http://dx.doi.org/10.1002/pros.24034DOI Listing

Negative Biopsy Histology in Men With PI-RADS Score 5 in Daily Clinical Practice: Incidence of Granulomatous Prostatitis.

Clin Genitourin Cancer 2020 Apr 14. Epub 2020 Apr 14.

Urology Unit, Cannizzaro Hospital, Catania, Italy.

Introduction: The purpose of this study was to evaluate the biopsy histology of men who underwent transperineal multi-parametric magnetic resonance imaging (mpMRI)/transrectal ultrasound fusion biopsy for Prostate Imaging Reporting and Data System (PI-RADS) score 5 lesions.

Patients And Methods: From January 2016 to June 2019, 105 men with PI-RADS score 5 underwent mpMRI/transrectal ultrasound fusion biopsy combined with systematic prostate biopsy. All the patients underwent a 3. Read More

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http://dx.doi.org/10.1016/j.clgc.2020.04.001DOI Listing

Granulomatous prostatitis: a challenging differential diagnosis to take into consideration.

Future Oncol 2020 May 17;16(13):805-806. Epub 2020 Mar 17.

Department of Neurosciences, Reproductive Sciences & Odontostomatology, University of Naples Federico II, Naples, Italy.

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http://dx.doi.org/10.2217/fon-2020-0185DOI Listing

Histopathology of nonspecific granulomatous prostatitis with special reference to eosinophilic epithelial metaplasia: Pathophysiologic, diagnostic and differential diagnostic correlations.

Indian J Pathol Microbiol 2020 Feb;63(Supplement):S34-S40

Department of Medical Biology, Medical University of Plovdiv; Technological Center for Emergency Medicine, Plovdiv, Bulgaria.

Background: Recently, we publish two case reports about association of nonspecific granulomatous prostatitis (NSGP) and eosinophilic metaplasia (EM) in benign prostatic epithelium. There is no investigation of large series of this association in medical literature. Aim of the current study is to investigate the frequency of association of NSGP and prostatic EM in a large series of cases and their relationship with the basic prostate pathology: benign prostatic hyperplasia (BPH), National Institutes of Health-category IV prostatitis (so-called histologic prostatitis (HP)), and prostatic adenocarcinoma (PCa). Read More

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http://dx.doi.org/10.4103/IJPM.IJPM_568_18DOI Listing
February 2020

GRANULOMATOUS DISEASE OF UNUSUAL SITES CAUSING HYPERCALCEMIA: TWO CASE REPORTS.

AACE Clin Case Rep 2019 Jan-Feb;5(1):e44-e49. Epub 2019 Jan 30.

Objective: Hypercalcemia with suppressed parathyroid hormone (PTH) levels is mostly due to granulomatous disease (GD) or neoplastic disease. In GD, autonomous activity of extra-renal 1α-hydroxylase enzyme is usually the underlying cause. We describe a pair of cases where hypercalcemia resulted from GD of unusual sites posing significant diagnostic challenges. Read More

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http://dx.doi.org/10.4158/ACCR-2018-0313DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6876985PMC
January 2019

[NON-SPECIFIC GRANULOMATOUS PROSTATITIS: A CASE REPORT].

Nihon Hinyokika Gakkai Zasshi 2019 ;110(1):65-69

Department of Urology, Yokosuka-Kyosai Hospital.

We report non-specific granulomatous prostatitis in a 58-year-old man who visited a Urology clinic with fever and dysuria. Digital rectal examination revealed prostatic tenderness, and laboratory examination of the urinary sediment revealed pyuria. Thus, he was diagnosed with acute bacterial prostatitis and treated with antibiotics. Read More

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http://dx.doi.org/10.5980/jpnjurol.110.65DOI Listing
January 2019

Granulomatous Prostatitis Mimicking Prostate Cancer.

Urology 2020 Mar 31;137:e3-e5. Epub 2019 Dec 31.

Department of Radiology, Kyung Hee University Hospital, School of Medicine, Kyung Hee University, Seoul, South Korea.

Multiparametric magnetic resonance imaging plays an important role in the detection of clinically significant prostate cancer. However, there is some overlap between prostate cancer and granulomatous prostatitis. We describe the imaging features of granulomatous prostatitis, which frequently mimics prostate cancer, and differential diagnosis between these conditions according to Prostate Imaging-Reporting and Data System (PI-RADS) version. Read More

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http://dx.doi.org/10.1016/j.urology.2019.12.028DOI Listing

Tuberculosis of the prostate gland masquerading prostate cancer; five cases experience at IGIMS.

Urol Ann 2019 Oct-Dec;11(4):389-392

Department of Urology, IGIMS, Patna, Bihar, India.

Objectives: Tuberculosis (TB) of the prostate is a very rare disease. Most urologists are not familiar with it. Here, we present our experience with five cases of this disease and a review of literature. Read More

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http://dx.doi.org/10.4103/UA.UA_119_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6798287PMC
October 2019

Xanthogranulomatous prostatitis presenting as prostatic abscesses: An uncommon complication after kidney transplantation.

IDCases 2019 10;17:e00559. Epub 2019 May 10.

Department of Medicine, Division of Infectious Diseases, University of Alberta, Edmonton, Alberta, Canada.

Xanthogranulomatous (XG) prostatitis is a rare form of granulomatous prostatitis characterized by a benign inflammatory process of non-specific etiology that clinically may mimic carcinoma. Few cases have been reported in the English language medical literature, with only four reported cases presenting as prostatic abscesses. A 70-year-old male with type 2 diabetes mellitus and two previous kidney transplants presented with septic shock secondary to bacteremia 4 days after undergoing a cystoscopy. Read More

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http://dx.doi.org/10.1016/j.idcr.2019.e00559DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6667697PMC
May 2019
8 Reads

FDG PET/CT in a Case of Bilateral Tuberculous Epididymo-orchitis.

Clin Nucl Med 2019 Sep;44(9):757-760

Department of Nuclear Medicine, Changhai Hospital, Second Military Medical University, Shanghai, China.

Isolated genital tuberculosis is rare. We present a case of bilateral tuberculous epididymo-orchitis showing high FDG uptake on FDG PET/CT. In addition, the patient had a prostatic FDG-avid lesion, consistent with tuberculous prostatitis. Read More

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http://dx.doi.org/10.1097/RLU.0000000000002606DOI Listing
September 2019
10 Reads

[Granulomatous Prostatitis : Three Cases Report].

Hinyokika Kiyo 2019 Mar;65(3):69-73

The Department of Pathology, Saiseikai Noe Hospital.

Case 1 : A 65-year-old man visited withfrequent urination and dysuria. Pyuria and bacteriuria were observed and prostate specific antigen (PSA) was elevated to 5.69 ng/ml. Read More

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http://hdl.handle.net/2433/241230
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http://dx.doi.org/10.14989/ActaUrolJap_65_3_69DOI Listing
March 2019
16 Reads

Multiparametric MRI appearances of primary granulomatous prostatitis.

Br J Radiol 2019 Jun 9;92(1098):20180075. Epub 2019 Apr 9.

4 Department of Radiology, Southend University Hospital, Westcliff-on-Sea , Essex , UK.

Objective: Radiological features of granulomatous prostatitis (GP) overlap with those of prostate adenocarcinoma. Identification of specific GP features may aid diagnosis. We aimed to evaluate the multiparametric MRI (mpMRI) features of GP. Read More

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http://dx.doi.org/10.1259/bjr.20180075DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592093PMC
June 2019
7 Reads

Case 258: Granulomatous Prostatitis.

Radiology 2018 10;289(1):267-271

From the Departments of Radiology (A.D.d.L., D.N.C., I.P.), Urology (I.P.), and Pathology (F.F.), and the Advanced Imaging Research Center (D.N.C., I.P.), University of Texas Southwestern Medical Center, 2201 Inwood Rd, 2nd Floor, Suite 202, Dallas, TX 75390-9085.

History A 68-year-old man with a remote history of a previously resected high-grade urothelial carcinoma in the renal pelvis was being observed and was undergoing urologic treatment for recurrent low-grade urothelial carcinoma of the bladder. During his most recent evaluation, he reported no specific symptoms and denied experiencing hematuria, dysuria, or abdominal pain. At routine surveillance MRI of the abdomen and pelvis (images not shown), a lesion was noted in the peripheral zone of the prostate gland. Read More

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http://dx.doi.org/10.1148/radiol.2018161272DOI Listing
October 2018
24 Reads

Histologic findings associated with false-positive multiparametric magnetic resonance imaging performed for prostate cancer detection.

Hum Pathol 2019 01 1;83:159-165. Epub 2018 Sep 1.

Department of Urology, University of Alabama at Birmingham, Birmingham, AL 35249, USA; Department of Radiology, University of Alabama at Birmingham, Birmingham, AL 35249, USA.

Magnetic resonance imaging (MRI)/ultrasound fusion-targeted biopsy (TB) has been shown to more accurately identify higher-grade prostate cancers compared with standard-of-care systematic sextant prostate biopsy (SB). However, occasional false-positive imaging findings occur. We investigated the histologic findings associated with false-positive prostate MRI findings. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00468177183033
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http://dx.doi.org/10.1016/j.humpath.2018.08.021DOI Listing
January 2019
48 Reads
2.769 Impact Factor

Prostatitis, a rare presentation of granulomatosis with polyangiitis, successfully treated with rituximab and prednisone.

BMJ Case Rep 2018 Aug 14;2018. Epub 2018 Aug 14.

Division of Rheumatology, Department of Medicine, Albany Medical Center, Albany, New York, USA.

A previously healthy 21-year-old man presented with an 8-month history of weight loss, lethargy and dysuria unresponsive to empiric antibiotics and paraurethral drainage of a prostatic abscess. Urinalysis showed pyuria, but cultures failed to grow any organisms. Additionally, he developed new onset sensorineural hearing loss. Read More

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http://casereports.bmj.com/lookup/doi/10.1136/bcr-2018-22537
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http://dx.doi.org/10.1136/bcr-2018-225379DOI Listing
August 2018
46 Reads

The distribution of BCG prostatitis: A clue for pathogenetic processes?

Prostate 2018 11 10;78(15):1134-1139. Epub 2018 Jul 10.

Department of Histopathology, Norfolk and Waveney Cellular Pathology Service, The Cotman Centre, Norfolk and Norwich University Hospitals NHS Foundation Trust, Norwich, Norfolk, UK.

Background: We observed in cystoprostatectomy specimens that Bacillus Calmette-Guérin (BCG) granulomatous prostatitis tended preferentially to affect the peripheral zone (PZ) and aimed to study the matter, postulating that assessment of its distribution might contribute to understanding pathogenetic processes.

Methods: Entire prostate glands from 27 men (47-83 years; mean = 69 years), who had previously received intravesical BCG therapy for non-muscle-invasive urothelial carcinoma of the bladder, were studied as whole-mount sections to determine the anatomical distribution and histopathological characteristics of BCG prostatitis.

Results: Twenty-two (81. Read More

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http://dx.doi.org/10.1002/pros.23688DOI Listing
November 2018
67 Reads

A novel view on the pathogenesis of complications after intravesical BCG for bladder cancer.

Int J Infect Dis 2018 Jul 17;72:63-68. Epub 2018 May 17.

Department of Infectious Diseases, Leiden University Medical Centre, Leiden, The Netherlands. Electronic address:

Intravesical bacillus Calmette-Guérin (BCG) is widely used for high-risk, non-muscle-invasive bladder cancer. This report describes four cases that illustrate the spectrum of BCG-induced complications, varying from granulomatous prostatitis to sepsis. There is considerable debate regarding whether inflammation or infection is the predominant mechanism in the pathogenesis of BCG disease. Read More

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http://dx.doi.org/10.1016/j.ijid.2018.05.006DOI Listing
July 2018
29 Reads

Treatment experience for incidentally diagnosed asymptomatic prostate tuberculosis in a patient with history of BCG intravesical therapy.

Urol Case Rep 2018 Mar 29;17:39-41. Epub 2017 Dec 29.

Department of Radiology in Trauma Center, Aju University School of Medicine, Suwon, South Korea.

Intravesical BCG therapy after transurethral resection of bladder tumor (TURB) is considered the most effective treatment for prophylaxis against the recurrence of high risk non-muscle invasive bladder cancer, and generally well tolerated and infectious complication are rare. We reported a case of granulomatous prostatitis is a patient who had undergone intravesical BCG therapy due to non-invasive superficial urothelial carcinoma of bladder. This patient was diagnosed by prostate biopsy because of PSA elevation without any other voiding symptoms and abnormal abscess pocket in transrectal ultrasonography. Read More

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http://dx.doi.org/10.1016/j.eucr.2017.12.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849809PMC
March 2018
19 Reads

A case of renal granulomatosis with polyangiitis following intravesical bacillus Calmette-Guérin therapy.

Saudi J Kidney Dis Transpl 2018 Jan-Feb;29(1):185-188

Department of Nephrology, La Rabta Hospital, Jebbari, Tunis, Tunisia.

Various adverse reactions may occur after intravesical bacillus Calmette-Guérin (BCG) therapy. Although the virulence of attenuated BCG is low, serious complications such as bacterial cystitis, bladder contractures, granulomatous prostatitis, epididymitis, orchitis, and systemic reactions such as fever and malaise have been described. Disseminated granulomatosis such as hepatitis and pneumonitis have also been described, but are rare. Read More

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http://dx.doi.org/10.4103/1319-2442.225178DOI Listing
October 2019
28 Reads

Nonspecific granulomatous prostatitis in association with eosinophilic epithelial metaplasia and prostatic adenocarcinoma.

Indian J Pathol Microbiol 2017 Jul-Sep;60(3):409-411

Department of General and Clinical Pathology, Medical University - Plovdiv, Plovdiv, Bulgaria.

We present the first case of nonspecific granulomatous prostatitis (NSGP) associated with both eosinophilic epithelial metaplasia (EM) in benign glands and prostatic adenocarcinoma (PCa). The patient was a 68-year old man with a history of obstructive prostatic syndrome. After a transurethral resection of the prostate, the histologic analysis revealed NSGP and PCa. Read More

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http://dx.doi.org/10.4103/IJPM.IJPM_130_16DOI Listing
May 2018
21 Reads

Pulmonary manifestations of urothelial carcinoma of the bladder.

Respir Med 2017 07 16;128:65-69. Epub 2017 May 16.

Northwell Health, Department of Pulmonary, Critical Care and Sleep Medicine, 410 Lakeville Rd. Suite 107, New Hyde Park, NY 11040, United States. Electronic address:

Urothelial carcinoma (Transitional cell carcinoma) of the bladder is the pre-dominant histological type of bladder cancer in the United States and Europe. Patients with bladder cancer usually present with painless hematuria. The diagnosis is often delayed, as the symptoms are similar to various other benign conditions such as urinary tract infection, prostatitis or renal calculi. Read More

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http://dx.doi.org/10.1016/j.rmed.2017.05.006DOI Listing
July 2017
152 Reads

Granulomatous prostatitis: clinical and histomorphologic survey of the disease in a tertiary care hospital.

Prostate Int 2017 Mar 12;5(1):29-34. Epub 2017 Jan 12.

Department of Pathology, Bhopal Memorial Hospital and Research Centre, Bhopal, India.

Background: Granulomatous prostatitis is an uncommon entity that is diagnosed incidentally on histopathology and is broadly classified as nonspecific, specific, postsurgical (post-transurethral resection), or secondary to other rare systemic granulomatous diseases. Only very few studies are available in the literature that describe the clinical and histomorphological spectrum of the disease.

Methods: A retrospective analysis of histopathological records of 1,181 prostatic specimens received in the pathology department was done over a period of 13 years (January 2003 to January 2016). Read More

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http://dx.doi.org/10.1016/j.prnil.2017.01.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357972PMC
March 2017
27 Reads

Clinical and multiparametric MRI signatures of granulomatous prostatitis.

Abdom Radiol (NY) 2017 07;42(7):1956-1962

Department of Urology, University of Alabama at Birmingham, Faculty Office Tower 1107, 510 20th Street South, Birmingham, AL, 3529, USA.

Purpose: The purpose of the study is to differentiate granulomatous prostatitis (GP) from high-grade prostate cancer (PCa) based on clinical findings and imaging characteristics on multiparametric MRI (MP-MRI).

Methods: Pathology from patients undergoing MRI/US fusion-guided prostate biopsies between 2014 and 2015 was reviewed. Five patients with biopsy proven GP were identified as well as 15 patients with biopsy-proven Gleason score ≥4 + 3 = 7 PCa. Read More

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http://dx.doi.org/10.1007/s00261-017-1080-0DOI Listing
July 2017
35 Reads

Multi-parametric MRI findings of granulomatous prostatitis developing after intravesical bacillus calmette-guérin therapy.

Abdom Radiol (NY) 2017 07;42(7):1963-1967

Rolling Oaks Radiology, 415 Rolling Oaks Dr #125, Thousand Oaks, CA, 91361, USA.

Purpose: To evaluate the multi-parametric MRI (mpMRI) findings in patients with biopsy-proven granulomatous prostatitis and prior Bacillus Calmette-Guérin (BCG) exposure.

Materials And Methods: MRI was performed in six patients with pathologically proven granulomatous prostatitis and a prior history of bladder cancer treated with intravesical BCG therapy. Multi-parametric prostate MRI images were recorded on a GE 750W or Philips Achieva 3. Read More

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http://dx.doi.org/10.1007/s00261-017-1081-zDOI Listing
July 2017
26 Reads

Granulomatous prostatitis after intravesical immunotherapy mimicking prostate cancer.

J Ultrason 2016 Dec 30;16(67):404-410. Epub 2016 Dec 30.

Department of Clinical Pathomorphology, Medical University of Lublin, Poland.

Intravesical immunotherapy with attenuated strains of is a widely used therapeutic option in patients with non-muscle-invasive transitional cell carcinoma of the bladder. A rare complication of intravesical therapy with the Bacillus Calmette-Guérin vaccine is granulomatous prostatitis, which due to increasing levels of prostate-specific antigen and abnormalities found in transrectal examination of the prostate may suggest concomitant prostate cancer. A case of extensive granulomatous prostatitis in a 61-year-old patient which occurred after the first course of a well-tolerated Bacillus Calmette-Guérin therapy is presented. Read More

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http://dx.doi.org/10.15557/JoU.2016.0040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5269527PMC
December 2016
25 Reads

Prostate-Specific Membrane Antigen PET/CT: False-Positive Results due to Sarcoidosis?

Case Rep Oncol 2016 May-Aug;9(2):457-463. Epub 2016 Aug 17.

Center for Radiotherapy and Radiooncology Bremen and Westerstede, Westerstede, Germany; Department for Radiotherapy, Karl-Lennert Cancer Center, University of Schleswig Holstein, Campus Kiel, Kiel, Germany.

We report on a 72-year-old male patient who developed sarcoidosis of the mediastinal lymph nodes, the liver, and the prostate 11 years ago. Seven years later, he underwent transurethral resection of the prostate by laser due to hematuria. Pathology of the resected chips showed a 'granulomatous prostatitis with epitheloid cells'. Read More

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http://dx.doi.org/10.1159/000447688DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5043264PMC
August 2016
31 Reads

Xanthogranulomatous prostatitis with prostato-rectal fistula: a case report and review of the literature.

Res Rep Urol 2016 16;8:165-168. Epub 2016 Sep 16.

Department of Urology, Tangshan People's Hospital, Tangshan, People's Republic of China.

Purpose: Xanthogranulomatous prostatitis (XP) is a rare form of nonspecific granulomatous prostatitis that can clinically mimic high-grade prostatic carcinoma. It is difficult to diagnose it definitely in clinical settings.

Methods: We report a case of XP with prostate-rectal fistula and review the relevant literatures. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5033499PMC
http://dx.doi.org/10.2147/RRU.S110658DOI Listing
September 2016
35 Reads

Disseminated tuberculosis with prostatic abscesses in an immunocompromised patient-A case report and review of literature.

IDCases 2016 23;5:15-20. Epub 2016 Jun 23.

Department of Pathology, Anatomy, and Cell Biology, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, PA 19107, United States.

We describe a case of disseminated Mycobacterium tuberculosis (mTB) with prostatic abscess in a newly diagnosed HIV patient in the United States. The patient is a 34 year-old male who presented with respiratory symptoms and was diagnosed with HIV/AIDS complicated by disseminated mTB infection of the lungs, liver, and prostate. His prostate showed abscess formation on imaging that required drainage however he did not present with any genitourinary complaints. Read More

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http://dx.doi.org/10.1016/j.idcr.2016.06.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4925914PMC
July 2016
45 Reads

Late-onset granulomatous prostatitis following intravesical bacille Calmette-Guerin therapy: case report.

Medwave 2016 Jun 20;16(5):e6473. Epub 2016 Jun 20.

Departamento Anatomía Patológica Clínica Santa María, Santiago, Chile.

Bacille Calmette-Guerin intravesical treatment is the most effective treatment for reducing the recurrence of non-muscle-invasive urothelial carcinomas. This treatment can sometimes have side effects and serious complications. Granulomatous prostatitis is a common histological finding but it rarely has a clinical presentation. Read More

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http://dx.doi.org/10.5867/medwave.2016.05.6473DOI Listing
June 2016
36 Reads

Radiologic presentation of chronic granulomatous prostatitis mimicking locally advanced prostate adenocarcinoma.

Radiol Case Rep 2016 Jun 16;11(2):78-82. Epub 2016 Mar 16.

Department of Radiology, Southend University Hospital, Prittlewell Chase, Westcliff-on-Sea, Essex, SS0 0RY, UK.

We present a case of nonspecific granulomatous prostatitis (GP), a clinical mimic of prostate adenocarcinoma. A 54-year-old man presented with lower urinary tract symptoms and raised prostate-specific antigen. Magnetic resonance imaging showed features consistent with prostate cancer, including low T2-signal intensity in the peripheral and transition zones with signs of extracapsular extension. Read More

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http://dx.doi.org/10.1016/j.radcr.2016.02.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878930PMC
June 2016
35 Reads

A Case of Epididymo-orchitis after intravesical bacille Calmette-Guérin therapy for superficial bladder carcinoma in a patient with latent tuberculosis infection.

Infect Agent Cancer 2016 2;11:25. Epub 2016 Jun 2.

Dipartimento di scienze per la promozione della salute e materno-infantile, Università di Palermo, via del vespro 129, Palermo, 90127 Italy.

Background: Intravesical instillation of bacille Calmette-Guérin (BCG) has been established as efficient therapy for superficial bladder carcinoma. Overall, intravesical BCG is well tolerated and results in complications of less than 5 %. However, adverse effects such as granulomatous prostatitis, pneumonitis, hepatitis, sepsis, and hypersensitivity reactions may occur. Read More

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http://dx.doi.org/10.1186/s13027-016-0072-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890504PMC
June 2016
25 Reads

Benign causes of diffusion restriction foci in the peripheral zone of the prostate: diagnosis and differential diagnosis.

Abdom Radiol (NY) 2016 05;41(5):910-8

Department of Radiology, Virginia Commonwealth University Health System, Main Hospital, 3rd Floor, 401 North 12th Street, P.O. Box 980615, Richmond, VA, 23298, USA.

Multiparametric-MRI is an important tool in the diagnosis of prostate cancer (PCa), particularly diffusion-weighted imaging for peripheral zone (PZ) cancer in the untreated prostate. However, there are many benign entities that demonstrate diffusion restriction in the PZ mimicking PCa resulting in diagnostic challenges. Fortunately, these benign entities usually have unique MR features that may help to distinguish them from PCa. Read More

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http://dx.doi.org/10.1007/s00261-016-0719-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871918PMC
May 2016
35 Reads

Clinicopathological Overview of Granulomatous Prostatitis: An Appraisal.

J Clin Diagn Res 2016 Jan 1;10(1):EC20-3. Epub 2016 Jan 1.

Professor, Department of Public Health Dentistry, ACPM Dental College , Dhule, Maharashtra, India .

Introduction: Granulomatous prostatitis is a rare inflammatory condition of the prostate. Granulomatous prostatitis is important because, it mimics prostatic carcinoma clinically and hence the diagnosis can be made only by histopathological examination.

Aim: To study the histomorphological features and to know the prevalence of granulomatous prostatitis. Read More

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http://dx.doi.org/10.7860/JCDR/2016/15365.7146DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740601PMC
January 2016
35 Reads

Granulomatous Prostatitis After Intravesical Bacillus Calmette-Guérin Instillation Therapy: A Potential Cause of Incidental F-18 FDG Uptake in the Prostate Gland on F-18 FDG PET/CT in Patients with Bladder Cancer.

Nucl Med Mol Imaging 2016 Mar 11;50(1):31-7. Epub 2015 Sep 11.

Department of Nuclear Medicine, Kyungpook National University Medical Center and School of Medicine, 807 Hoguk-ro, Buk-gu, Daegu, 702-210 Republic of Korea.

Purpose: This study aimed to evaluate the possibility that Bacillus Calmette-Guérin (BCG)-induced granulomatous prostatitis can be a potential cause of benign F-18 FDG uptake.

Methods: A total of 395 bladder cancer patients who underwent F-18 FDG PET/CT (PET/CT) were retrospectively evaluated. Patients were divided into two groups according to BCG therapy status. Read More

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http://dx.doi.org/10.1007/s13139-015-0364-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4762869PMC
March 2016
78 Reads

Benign Conditions That Mimic Prostate Carcinoma: MR Imaging Features with Histopathologic Correlation.

Radiographics 2016 Jan-Feb;36(1):162-75. Epub 2015 Nov 20.

From the Departments of Medical Imaging (Y.X.K.) and Urology (C.V.), Macquarie University Hospital, Sydney, Australia; Department of Radiology, Hospital Vera Cruz, Campinas, Brazil (A.P.); Department of Radiology, University of Chicago, Chicago, Ill (G.S.K., A.O.); and Douglass Hanly Moir Pathology, Sydney, Australia (F.M.).

Multiparametric magnetic resonance (MR) imaging combines anatomic and functional imaging techniques for evaluating the prostate and is increasingly being used in diagnosis and management of prostate cancer. A wide spectrum of anatomic and pathologic processes in the prostate may masquerade as prostate cancer, complicating the imaging interpretation. The histopathologic and imaging findings of these potential mimics are reviewed. Read More

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http://dx.doi.org/10.1148/rg.2016150030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496681PMC
October 2016
72 Reads

Urologic and male genital manifestations of granulomatosis with polyangiitis.

Autoimmun Rev 2015 Oct 28;14(10):897-902. Epub 2015 May 28.

Vasculitis Research Unit, Department of Systemic Autoimmune Diseases, Hospital Clínic, University of Barcelona, Institut d'Investigacions Biomèdiques August Pi Sunyer (IDIBAPS), Barcelona, Spain. Electronic address:

Granulomatosis with polyangiitis (GPA) is a systemic necrotizing granulomatous vasculitis, which predominantly affects small-sized blood vessels. Major organ involvement includes the upper/lower respiratory tract and kidneys. In contrast, genitourinary disease is rare in GPA patients, reported in <1% of cases in large cohorts. Read More

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http://dx.doi.org/10.1016/j.autrev.2015.05.012DOI Listing
October 2015
17 Reads

Multiphase contrast-enhanced magnetic resonance imaging features of Bacillus Calmette-Guérin-induced granulomatous prostatitis in five patients.

Korean J Radiol 2015 Mar-Apr;16(2):342-8. Epub 2015 Feb 27.

Department of Radiology, Gifu University Hospital, Gifu 501-1194, Japan.

Objective: To evaluate the multiphase contrast-enhanced magnetic resonance (MR) imaging features of Bacillus Calmette-Guérin (BCG)-induced granulomatous prostatitis (GP).

Materials And Methods: Magnetic resonance images obtained from five patients with histopathologically proven BCG-induced GP were retrospectively analyzed for tumor location, size, signal intensity on T2-weighted images (T2WI) and diffusion-weighted images (DWI), apparent diffusion coefficient (ADC) value, and appearance on gadolinium-enhanced multiphase images. MR imaging findings were compared with histopathological findings. Read More

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http://dx.doi.org/10.3348/kjr.2015.16.2.342DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4347270PMC
August 2015
31 Reads

Orchitis and Epididymitis in Koalas (Phascolarctos cinereus) Infected With Chlamydia pecorum.

Vet Pathol 2015 Nov 30;52(6):1254-7. Epub 2015 Jan 30.

Faculty of Veterinary Science, The University of Sydney, Australia.

Although Chlamydia causes disease of the urethra and prostate of male koalas, its impact on the testis and epididymis has not been examined. This study describes chronic-active and granulomatous orchitis and epididymitis with interstitial fibrosis associated with infection by Chlamydia pecorum in 2 of 18 adult male koalas being euthanized at a koala hospital, 8 of which also had chlamydial prostatitis. By immunohistochemistry and transmission electron microscopy, chlamydial inclusions were demonstrated within Sertoli cells directly associated with mild inflammation surrounding intact seminiferous and epididymal tubules, marked pyogranulomatous inflammation around disrupted tubules, replacement of tubules by interstitial fibrosis, and aspermia. Read More

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http://dx.doi.org/10.1177/0300985815570069DOI Listing
November 2015
20 Reads

Bacillus Calmette-Guérin therapy-associated granulomatous prostatitis mimicking prostate cancer on MRI: A case report and literature review.

Mol Clin Oncol 2015 Jan 19;3(1):249-251. Epub 2014 Sep 19.

Department of Radiology, St. Spiridon Hospital, Gr. T. Popa University of Medicine, 700111 Iasi, Romania.

Granulomatous prostatitis following bacillus Calmette-Guérin (BCG) immunotherapy is a well-known pathological entity, developing following initiation of BCG therapy as a prophylactic measure against the recurrence of non-muscle invasive bladder cancer. In addition, there are certain imaging similarities between granulomatous prostatitis and prostate cancer, including hypoechoic area on transrectal ultrasonography and low T2 signal intensity in some prostate areas on magnetic resonance imaging (MRI). This is the report of a case exhibiting a perfect imaging cross-match between granulomatous prostatitis and potential prostate cancer on repeated MRI exams, adding two supplementary aspects to the already known similarities, namely progressive restricted diffusion and increased contrast enhancement, which are specific to prostate cancer. Read More

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http://dx.doi.org/10.3892/mco.2014.422DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4251198PMC
January 2015
39 Reads

Incidental detection of increased (18)F-FDG uptake and its follow-up in patients with granulomatous prostatitis after BCG treatment for urinary bladder cancer.

Hell J Nucl Med 2014 Sep-Dec;17(3):204-7. Epub 2014 Nov 12.

Department of Nuclear Medicine, Kyungpook National University, Medical Center and School of Medicine, 807 Hoguk-ro, Buk-gu, Daegu, 702-210, Republic of Korea.

Incidental prostate uptake of fluorine-18-fluorodeoxyglucose in positron emission tomography/computed tomography ((18)F-FDG PET/CT) may represent malignancies like prostate malignancy, inflammation or benign prostatic lesions. We report two cases of bacillus Calmette-Guérin (BCG)-induced granulomatous prostatitis that showed (18)F-FDG uptake of the prostate gland on (18)F-FDG PET/CT in patients who had previously received intravesical BCG treatment for bladder cancer. The degree of (18)F-FDG uptake was decreased on the follow-up PET/CT scan after one year, without any specific treatment. Read More

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http://dx.doi.org/10.1967/s002449910146DOI Listing
March 2015
44 Reads

Granulomatous prostatitis: a rare diagnosis of prostatic disease.

Minerva Urol Nefrol 2014 Sep;66(3):201-2

Department of Urology, Haydarpaşa Numune Training and Research Hospital, Istanbul, Turkey -

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September 2014
24 Reads

Investigation of granulomatous prostatitis incidence following intravesical BCG therapy.

Int J Clin Exp Med 2014 15;7(6):1554-7. Epub 2014 Jun 15.

Department of Urology, Meram Medical School, Necmettin Erbakan University Konya, Turkey.

Unlabelled: In the present manuscript, we studied the incidence of granulomatous prostatitis in the prostatectomy specimen of the patients who underwent transurethral resection of the prostate (TURP) after superficial bladder cancer treatment with intravesical Bacillus Calmette-Guerin (BCG) and were diagnosed with benign prostate hyperplasia (BPH). The clinical data and histopathological specimen records of 472 patients who underwent TUR-P due to BPH diagnosis, obtained over a period of 6 years in the urology department of Private Konya Hospital, Konya, Turkey, were studied retrospectively. The cases were divided into two groups as (Group I) who did not undergo any treatment and as (Group II) who underwent BCG treatment. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100965PMC
July 2014
85 Reads

Best practices recommendations in the application of immunohistochemistry in the prostate: report from the International Society of Urologic Pathology consensus conference.

Am J Surg Pathol 2014 Aug;38(8):e6-e19

*Departments of Pathology, Urology, and Oncology, The John Hopkins Medical Institutions, Baltimore, MD ‡Department of Pathology, Yale University School of Medicine, New Haven, CT †Department of Oncology-Pathology, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden §Section of Pathological Anatomy, Polytechnic University of the Marche Region, School of Medicine, United Hospitals, Ancona, Italy.

The following are the International Society of Urological Pathology (ISUP) recommendations for the use of immunohistochemistry (IHC) in prostate specimens. Either high-molecular weight cytokeratin (34βE12 or CK5/6 or others) or p63 or a combination of the 2 with AMACR either in a double or triple cocktail is recommended for the workup of small foci of atypical glands suspicious for adenocarcinoma of the prostate (PCa). ERG is optional as it is present in only 40% to 50% of prostate cancers and also positive in high-grade prostatic intraepithelial neoplasia. Read More

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http://pdfs.journals.lww.com/ajsp/9000/00000/Best_Practices_
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http://pdfs.journals.lww.com/ajsp/2014/08000/Best_Practices_
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http://dx.doi.org/10.1097/PAS.0000000000000238DOI Listing
August 2014
58 Reads

Multiparametric MRI findings of granulomatous prostatitis after intravesical bacillus Calmette-Guérin therapy in a patient undergoing active surveillance.

Clin Genitourin Cancer 2014 Oct 10;12(5):e215-9. Epub 2014 Jun 10.

Russell H. Morgan Department of Radiology, Johns Hopkins Medical Institutions, Baltimore, MD; James Buchanan Brady Urological Institute, Johns Hopkins Medical Institutions, Baltimore, MD. Electronic address:

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http://dx.doi.org/10.1016/j.clgc.2014.03.015DOI Listing
October 2014
26 Reads

Xanthogranulomatous prostatitis: multiparametric MRI appearances.

Clin Imaging 2014 Sep-Oct;38(5):755-7. Epub 2014 Mar 22.

Department of Radiology, Tianjin First Central Hospital, Tianjin, China, 300192. Electronic address:

Granulomatous prostatitis is an unusual form of prostatitis, and xanthogranulomatous prostatitis (XGP) is an even rarer granulomatous inflammation. Very few XGP cases have been reported in the literature. The reports concerning MRI features of XGP are even less. Read More

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http://search.proquest.com/openview/e87ac48a9eb5ad00880602cb
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http://linkinghub.elsevier.com/retrieve/pii/S089970711400073
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http://dx.doi.org/10.1016/j.clinimag.2014.03.008DOI Listing
May 2015
24 Reads

Changes observed in multiparametric prostate magnetic resonance imaging characteristics correlate with histopathological development of chronic granulomatous prostatitis after intravesical Bacillus Calmette-Guerin therapy.

J Comput Assist Tomogr 2014 Mar-Apr;38(2):274-6

From the *Urologic Oncology Branch, †Laboratory of Pathology, ‡Molecular Imaging Program, and §Center for Interventional Oncology, National Cancer Institute, National Institutes of Health, Bethesda, MD.

Administration of Bacillus Calmette-Guerin (BCG) has been shown to cause granulomatous prostatitis, a rare inflammatory process that can be mistaken for prostate cancer. We present a case of a 78-year-old man on active surveillance for prostate cancer with a subsequent diagnosis of high-grade urothelial carcinoma. After intravesical BCG therapy, he developed chronic granulomatous prostatitis. Read More

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http://dx.doi.org/10.1097/RCT.0b013e3182aac58aDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995030PMC
May 2014
20 Reads

Hematospermia and xanthogranulomatous prostatitis: An unusual onset of a rare diagnosis.

Can Urol Assoc J 2013 Nov-Dec;7(11-12):E820-2

Sapienza University of Rome, Faculty of Pharmacy and Medicine; Department of Medico-Surgical Sciences and Biotechnologies, Urology Unit - I.C.O.T, Latina, Italy;

Xanthogranulomatous prostatitis is a rare type of granulomatous prostatitis, with very few cases described. We report the clinical, radiological and pathological findings of 5 cases of xanthogranulomatous prostatitis. All patients came for recurrent episodes of hematospermia (associated with fever in 3 patients). Read More

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http://dx.doi.org/10.5489/cuaj.1525DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879734PMC
January 2014
24 Reads

Diagnostic dilemma in histopathology report following robot assisted laparoscopic prostatectomy: tumour 'hide and seek'.

Indian J Cancer 2013 Jul-Sep;50(3):170-4

Department of Urology, All India Institute of Medical Sciences, New Delhi, India.

Introduction: Widespread PSA (prostate specific antigen) screening has resulted in stage migration of prostate cancer. Smaller tumor volumes are being detected in radical prostatectomy specimens. This has coincided with increasing reports about the 'vanishing cancer phenomenon. Read More

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http://dx.doi.org/10.4103/0019-509X.118719DOI Listing
March 2014
9 Reads