271 results match your criteria Granulomatous Prostatitis

PD-L1 positive lympho-epithelial lesions in inflammatory prostate.

Histol Histopathol 2022 Jun 7:18479. Epub 2022 Jun 7.

Department of Medical Biology, Research Institute at Medical Faculty, Medical University of Plovdiv, Bulgaria.

Objectives: Ductal epithelial changes (lympho-epithelial lesions-LEL) in prostatic chronic inflammation (CI) are not well studied so far.

Aim: to investigate LEL immediately adjacent to prostatic CI.

Methods: We studied LEL in 144 prostatic surgical and autopsy specimens in various types of prostatic CI: NIH-category IV prostatitis (histologic prostatitis-HP), nonspecific granulomatous prostatitis (NSGP), and the reactive lymphoid infiltrates in the vicinity of benign prostatic hyperplasia (BPH) and prostate adenocarcinoma (PCa). Read More

View Article and Full-Text PDF

68Ga-DOTATATE and 68Ga-PSMA Uptake in Granulomatous Prostatitis.

Dan Ruan Long Sun

Clin Nucl Med 2022 Apr;47(4):359-361

Department of Nuclear Medicine and Minnan PET Center, Xiamen Cancer Hospital, The First Affiliated Hospital of Xiamen University, Xiamen, China.

Abstract: 68Ga-PSMA and 68Ga-DOTATATE PET/CT have shown promising performance in diagnosing prostate cancer and neuroendocrine tumors, but there are also pitfalls. We report a case of a 78-year-old man with prostate lesions showing intense uptake of 18FDG, 68Ga-PSMA, and 68Ga-DOTATATE simultaneously, with heterogeneous enhancement on contrast-enhanced CT and abnormal signal changes on PET/MRI. It was finally diagnosed as granulomatous prostatitis. Read More

View Article and Full-Text PDF

Imaging Patterns of Bacillus Calmette-Guérin-Related Granulomatous Prostatitis Based on Multiparametric MRI.

Korean J Radiol 2022 01;23(1):60-67

Department of Radiology, Research Institute and Hospital, National Cancer Center, Goyang, Korea.

Objective: To categorize multiparametric MRI features of Bacillus Calmette-Guérin (BCG)-related granulomatous prostatitis (GP) and discover potential manifestations for its differential diagnosis from prostate cancer.

Materials And Methods: The cases of BCG-related GP in 24 male (mean age ± standard deviation, 66.0 ± 9. Read More

View Article and Full-Text PDF
January 2022

Cryptococcal Prostatitis Forming Caseous and Suppurative Granulomas Diagnosed by Needle Biopsy: A Case Report.

Int J Surg Pathol 2021 Dec 31:10668969211070170. Epub 2021 Dec 31.

12756Dokkyo Medical University, Mibu, Tochigi, Japan.

Cryptococcal granulomatous prostatitis is extremely rare, and there have been few reports of its diagnosis by prostate needle biopsy. The patient, an 81-year-old man, was receiving immunosuppressive treatment for rheumatoid arthritis. He had an oropharyngeal ulcer, and it was diagnosed alongside a methotrexate-related diffuse large B-cell lymphoma. Read More

View Article and Full-Text PDF
December 2021

An ambivalent prostate nodule after Bacillus Calmette-Guérin therapy.

IDCases 2021 16;26:e01338. Epub 2021 Nov 16.

Infectious and Tropical Disease Unit, CHU Clermont-Ferrand, 58 Rue Montalembert, France.

A 65-year-old patient without specific associated pathology was treated for a high-grade non-invasive papillary urothelial carcinoma by surgery associated with repeated intravesical Bacillus Calmette-Guérin (BCG) instillations. During follow-up, magnetic resonance imaging (MRI) found a clinically indurated prostate nodule with suspected extensive capsular invasion. Prostatic biopsies showed epithelioid and giant-cell granuloma associated with a single focus of adenocarcinoma. Read More

View Article and Full-Text PDF
November 2021

Granulomatous and xanthogranulomatous prostatitis: A case report.

Urol Case Rep 2022 Jan 12;40:101887. Epub 2021 Oct 12.

Department of Surgery, Urology Section, Hamad Medical Corporation, Doha, Qatar.

Granulomatous prostatitis is a rare condition that is diagnosed only by histopathological examination. Though rare, the condition was reported to have different presentations (mimicking prostate cancer or prostatitis and prostatic abscess) and to have different etiologies which classified it into three main entities; nonspecific (idiopathic), post-surgery, and specific. Specific granulomatous prostatitis is further sub-classified to infective, xanthogranulomatous, Malacoplakia and associated with systemic granulomatous disease and allergy. Read More

View Article and Full-Text PDF
January 2022

Lymphoplasmacytic Prostatitis Associated With Urethral Obstruction in a Dog; A Case Report.

Top Companion Anim Med 2022 Jan-Feb;46:100593. Epub 2021 Oct 23.

Department of Internal Medicine, Companion Animal Clinic (Unit of Medicine), School of Veterinary Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, Greece.

A 10-year-old, male intact, mixed breed dog was admitted with a history of intermittent lower urinary tract signs of 18-months duration. Dysuria, stranguria, pollakiuria and overflow incontinence developed 2 weeks prior to presentation, while vomiting, polydipsia and anorexia were seen a few days prior to admission. Physical examination revealed prostatomegaly. Read More

View Article and Full-Text PDF
January 2022

Prostatic lithiasis complicating granulomatous prostatis of tuberculous origin: About a case report.

Urol Case Rep 2022 Jan 1;40:101875. Epub 2021 Oct 1.

Departement of Urology, La Rabta Hospital, Tunisia.

Urogenital tuberculosis remains a frequent disease in our country. It is the most common extra-pulmonary location. Prostatic involvement is extremely rare. Read More

View Article and Full-Text PDF
January 2022

Rapidly recurrent prostatic obstruction due to granulomatosis with polyangiitis.

Urol Case Rep 2021 Nov 7;39:101771. Epub 2021 Jul 7.

Anatpath, 120 Gardenvale Road, Gardenvale, VIC, 3185, Australia.

Granulomatosis with polyangiitis (GPA) is a rare cause of prostatitis. Our case illustrates a case of granulomatous prostatitis secondary to unrecognised GPA requiring multiple surgical interventions. The patient presented with lower urinary tract symptoms. Read More

View Article and Full-Text PDF
November 2021

Multiparametric Magnetic Resonance Imaging in Evaluation of Clinically Significant Prostate Cancer.

Indian J Radiol Imaging 2021 Jan 23;31(1):65-77. Epub 2021 May 23.

Department of Imaging Sciences and Pathology, Saifee Hospital, Mumbai, Maharashtra, India.

 In this prospective study, we evaluate the role of multiparametric magnetic resonance imaging (mp-MRI) in the assessment of clinically significant prostate cancer at 1.5 T without endorectal coil (ERC).  Forty-five men with clinical suspicion of prostate cancer (prostate-specific antigen [PSA] level > 4 ng/mL, hard prostate on digital rectal examination, and suspicious area at transrectal ultrasound [TRUS]) were evaluated using the mp-MRI protocol over a period of 24 months. Read More

View Article and Full-Text PDF
January 2021

The role of prostate-specific antigen and multiparametric magnetic resonance imaging in the diagnosis of granulomatous prostatitis induced by intravesical Bacillus Calmette-Guérin vaccine therapy in patients with nonmuscle invasive bladder cancer.

J Cancer Res Ther 2021 Jul;17(3):625-629

Department of Urology, Cheeloo College of Medicine, Shandong Provincial Hospital, Shandong University; Department of Urology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China.

Aims: This study aimed to evaluate the role of serum prostate-specific antigen (PSA) levels and multiparametric magnetic resonance imaging (mpMRI) in the diagnosis of granulomatous prostatitis (GP) induced by intravesical Bacillus Calmette-Guérin vaccine (BCG) therapy in patients with nonmuscle invasive bladder cancer (NMIBC).

Subjects And Methods: We retrospectively analyzed eight patients with bladder cancer who underwent intravesical BCG therapy after transurethral resection of bladder tumor (TURBt) cancer. All these eight patients received 12-core transrectal ultrasound-guided prostate systemic biopsies. Read More

View Article and Full-Text PDF

Editorial Comment to Granulomatous prostatitis with high suspicion of prostatic adenocarcinoma on radiological imaging.

IJU Case Rep 2021 Jul 16;4(4):250. Epub 2021 May 16.

Department of Urology Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Okayama University Okayama Japan.

View Article and Full-Text PDF

Granulomatous prostatitis with high suspicion of prostatic adenocarcinoma on radiological imaging.

IJU Case Rep 2021 Jul 6;4(4):247-249. Epub 2021 May 6.

Departments of Department of Urology NTT Medical Center Hospital Shinagawa-ku Japan.

Introduction: Granulomatous prostatitis is a benign inflammatory condition of the prostate that may mimic prostatic adenocarcinoma on magnetic resonance imaging findings. Even in the era of multiparametric magnetic resonance imaging, the differential diagnosis of granulomatous prostatitis from malignancy remains difficult.

Case Presentation: A 69-year-old man with abnormal magnetic resonance imaging and positron emission tomography/magnetic resonance imaging findings, and a prostate-specific antigen value of 2. Read More

View Article and Full-Text PDF

Differential diagnosis of uncommon prostate diseases: combining mpMRI and clinical information.

Insights Imaging 2021 Jun 16;12(1):79. Epub 2021 Jun 16.

Department of Radiology, Peking University First Hospital, No. 8 Xishiku Street, Xicheng District, Beijing, 100034, China.

The differential diagnosis of abnormalities in the prostate is broad, covering common (acinar adenocarcinoma, benign prostatic hyperplasia, chronic prostatitis, hemorrhage, cysts, calcifications, atrophy and fibrosis) and less common conditions (tumors other than acinar adenocarcinoma, granulomatous prostatitis containing tuberculosis, abscesses and other conditions, and idiopathic disorders such as amyloidosis and exophytic benign prostatic hyperplasia). Recent advances in magnetic resonance imaging (MRI) of the prostate gland and imaging guidelines, such as the Prostate Imaging Reporting and Data System version 2.1 (PI-RADS v2. Read More

View Article and Full-Text PDF

Prostatitis: imaging appearances and diagnostic considerations.

Clin Radiol 2021 Jun 22;76(6):416-426. Epub 2021 Feb 22.

Department of Radiology, Division of Abdominal Imaging, Massachusetts General Hospital, 55 Fruit Street, Boston, MA, 02114, USA.

Acute and chronic inflammation of the prostate gland can be attributed to several underlying aetiologies, including but not limited to, bacterial prostatitis, granulomatous prostatitis, and Immunoglobulin G4-related prostatitis. In this review, we provide an overview of the general imaging appearances of the different types of prostatitis, their distinguishing features and characteristic appearances at cross-sectional imaging. Common imaging pitfalls are presented and illustrated with examples. Read More

View Article and Full-Text PDF

Comparative prostate MRI before and after chronic granulomatous prostatitis following intravesical bacillus Calmette-Guérin therapy.

Future Sci OA 2020 Oct 20;7(2):FSO637. Epub 2020 Oct 20.

Department of Urology, Saint Joseph Hospital, Beirut, Lebanon.

Background: Granulomatous prostatitis (GnP) is an interesting complication of bacillus Calmette-Guérin (BCG) therapy as it mimics prostate cancer on clinical, biochemical and imaging examinations. In the era of multiparametric prostate MRI (mpMRI), differentiation of GnP from prostate cancer on imaging is essential.

Case Presentation: We report a case of post-BCG GnP in a patient with nonmuscle invasive bladder cancer, presenting with a prostate-specific antigen level of 21. Read More

View Article and Full-Text PDF
October 2020

Epidemiological study of granulomatous prostatitis in a tertiary hospital: Associated risk factors and relationship with prostate cancer.

Urologia 2022 May 10;89(2):257-260. Epub 2020 Dec 10.

Department of Urology, Son Espases University Hospital, Palma de Mallorca, Baleares, Spain.

Objective: The primary objective was to estimate the incidence of granulomatous prostatitis (GP) in Son Espases University Hospital, a tertiary care hospital, in Palma de Mallorca (Spain). As secondary objectives, presence of concomitant PCa in the biopsy was analyzed, as well as the history of previous BCG instillations, biopsy origin, urinary symptoms, and cardiovascular risk (CV) factors.

Methods: A descriptive retrospective study of GP and the aforedescribed variables were carried out from 2010 to 2017. Read More

View Article and Full-Text PDF

Prostate tuberculosis complicated by huge prostatic abscess: A rare case report from Nepal.

Int J Surg Case Rep 2020 2;77:152-156. Epub 2020 Nov 2.

Department of Pathology, Lumbini Medical College and Teaching Hospital Ltd Tansen-11, Pravas, Palpa, Nepal. Electronic address:

Introduction: Prostatic tuberculosis is one of the rarest findings in clinical practice and associated prostatic abscess is even scarce, described in literatures. We present a rare case of prostatic tuberculosis complicated by huge prostatic abscess.

Presentation Of A Case: A 68-year-old male with no any comorbidity presented with history of increased frequency of micturition along with poor flow, urgency and nocturia for 17 days. Read More

View Article and Full-Text PDF
November 2020

Prediction of clinically significant prostate cancer after negative prostate biopsy: The current value of microscopic findings.

Urol Oncol 2021 07 5;39(7):432.e11-432.e19. Epub 2020 Nov 5.

Department of Urology, Vall d´Hebron Hospital, Barcelona, Spain; Research group in Urology. Vall d´Hebron Research Institute; Universitat Autònoma de Barcelona, Barcelona, Spain.

Objective: To assess the current ability of atypical small acinar proliferation (ASAP), multifocal high-grade prostatic intraepithelial neoplasia (mHGPIN), HGPIN with atypia (PINATYP) and other non-malignant lesions to predict clinically significant prostate cancer (csPCa) in repeat prostate biopsies.

Methods: This retrospective study analyzed 377 repeat prostate biopsies, carried out between 2.014 and 2. Read More

View Article and Full-Text PDF

A Case of Burkholderia Prostatitis in a Patient with Chronic Granulomatous Disease.

J Clin Immunol 2020 11 16;40(8):1204-1206. Epub 2020 Sep 16.

Department of Immunology, Royal Free Hospital, Pond Street, Hampstead, London, UK.

View Article and Full-Text PDF
November 2020

Varied Presentation of Fulminant Blastomycosis with Prostatitis and Acute Respiratory Distress Syndrome in a Patient With High Inoculum Inhalation: A Review of Diagnosis and Management.

Cureus 2020 Aug 12;12(8):e9686. Epub 2020 Aug 12.

Internal Medicine, SVS Medical College, Hyderabad, IND.

Blastomycosis is an uncommon granulomatous disease caused by infection with thermally dimorphic fungi of the genus Blastomyces. Although pulmonary infections from Blastomyces dermatitidis are uncommon, it is important to understand the geographical distribution, presentation, diagnosis, and management of treating this condition. We report a case of fulminant blastomycosis after high inoculum inhalation, with involvement of the prostate on presentation, which progressed to acute respiratory distress syndrome. Read More

View Article and Full-Text PDF

Granulomatous prostatitis mimicking prostate cancer in a patient with psoriatic arthritis: a case report.

Future Sci OA 2020 Jun 17;6(7):FSO591. Epub 2020 Jun 17.

Department of Neuroscience, Reproductive Sciences & Odontostomatology, University of Naples Federico II, Naples, Italy.

Granulomatous prostatitis (GP) is an unusual and benign inflammatory condition of the prostate, where autoimmunity has been recognized as a key factor in the pathogenesis of GP in a subset of patients. Clinically, GP poses diagnostic challenges as it may strongly mimic prostate cancer from a clinical, biochemical and radiological point of view. The occurrence of GP in patients suffering from psoriasis, a systemic autoimmune disease, has never been investigated. Read More

View Article and Full-Text PDF

[An abscessed granulomatous prostatitis].

Rev Med Interne 2020 Aug 13;41(8):562-566. Epub 2020 Jul 13.

Service de Médecine Interne, Hôpital Ambroise Paré, Université Paris Saclay, 9 Avenue Charles de Gaulle, 92100 Boulogne-Billancourt, France.

Introduction: Prostatic abscesses are usually diagnosed in the setting of bacterial prostatitis. Rarely, they reveal or complicate granulomatous prostatitis.

Case Report: A 55-year-old man was admitted for acute urinary retention. Read More

View Article and Full-Text PDF

Fungal prostatitis due to endemic mycoses and Cryptococcus: A multicenter case series.

Prostate 2020 09 22;80(12):1006-1011. Epub 2020 Jun 22.

Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, Maryland.

Background: Fungal prostatitis is exceedingly rare with mostly case reports.

Methods: Electronic medical records at three medical centers were searched for cases of fungal prostatitis due to endemic mycoses and Cryptococcus over the preceding 10 years.

Results: Seven cases were identified from 105 600 prostate biopsies within the Southern California Permanente Medical Group for an incidence of 0. Read More

View Article and Full-Text PDF
September 2020

Negative Biopsy Histology in Men With PI-RADS Score 5 in Daily Clinical Practice: Incidence of Granulomatous Prostatitis.

Clin Genitourin Cancer 2020 12 14;18(6):e684-e687. Epub 2020 Apr 14.

Urology Unit, Cannizzaro Hospital, Catania, Italy.

Introduction: The purpose of this study was to evaluate the biopsy histology of men who underwent transperineal multi-parametric magnetic resonance imaging (mpMRI)/transrectal ultrasound fusion biopsy for Prostate Imaging Reporting and Data System (PI-RADS) score 5 lesions.

Patients And Methods: From January 2016 to June 2019, 105 men with PI-RADS score 5 underwent mpMRI/transrectal ultrasound fusion biopsy combined with systematic prostate biopsy. All the patients underwent a 3. Read More

View Article and Full-Text PDF
December 2020

Granulomatous prostatitis: a challenging differential diagnosis to take into consideration.

Future Oncol 2020 May 17;16(13):805-806. Epub 2020 Mar 17.

Department of Neurosciences, Reproductive Sciences & Odontostomatology, University of Naples Federico II, Naples, Italy.

View Article and Full-Text PDF

Histopathology of nonspecific granulomatous prostatitis with special reference to eosinophilic epithelial metaplasia: Pathophysiologic, diagnostic and differential diagnostic correlations.

Indian J Pathol Microbiol 2020 Feb;63(Supplement):S34-S40

Department of Medical Biology, Medical University of Plovdiv; Technological Center for Emergency Medicine, Plovdiv, Bulgaria.

Background: Recently, we publish two case reports about association of nonspecific granulomatous prostatitis (NSGP) and eosinophilic metaplasia (EM) in benign prostatic epithelium. There is no investigation of large series of this association in medical literature. Aim of the current study is to investigate the frequency of association of NSGP and prostatic EM in a large series of cases and their relationship with the basic prostate pathology: benign prostatic hyperplasia (BPH), National Institutes of Health-category IV prostatitis (so-called histologic prostatitis (HP)), and prostatic adenocarcinoma (PCa). Read More

View Article and Full-Text PDF
February 2020


AACE Clin Case Rep 2019 Jan-Feb;5(1):e44-e49. Epub 2019 Jan 30.

Objective: Hypercalcemia with suppressed parathyroid hormone (PTH) levels is mostly due to granulomatous disease (GD) or neoplastic disease. In GD, autonomous activity of extra-renal 1α-hydroxylase enzyme is usually the underlying cause. We describe a pair of cases where hypercalcemia resulted from GD of unusual sites posing significant diagnostic challenges. Read More

View Article and Full-Text PDF
January 2019


Nihon Hinyokika Gakkai Zasshi 2019 ;110(1):65-69

Department of Urology, Yokosuka-Kyosai Hospital.

We report non-specific granulomatous prostatitis in a 58-year-old man who visited a Urology clinic with fever and dysuria. Digital rectal examination revealed prostatic tenderness, and laboratory examination of the urinary sediment revealed pyuria. Thus, he was diagnosed with acute bacterial prostatitis and treated with antibiotics. Read More

View Article and Full-Text PDF