277 results match your criteria Granuloma Faciale

A rare case of granuloma faciale presenting with ulceration: A case report.

SAGE Open Med Case Rep 2022 24;10:2050313X221093150. Epub 2022 Apr 24.

Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada.

Granuloma faciale is an uncommon inflammatory dermatosis characterized by persistent dermal plaques, typically on the face, that mimic granulomatous disorders like sarcoidosis. Ulceration of granuloma faciale has very rarely been reported, and the plaques are usually asymptomatic and of cosmetic impact. We present a case of an 83-year-old male with recurrent granuloma faciale with spontaneous ulceration and monoclonal gammopathy of undetermined significance. Read More

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Identifying histopathologic features of erythema elevatum diutinum and granuloma faciale.

J Cutan Pathol 2022 03 4;49(3):323-326. Epub 2022 Jan 4.

Department of Dermatology, University of Florida College of Medicine, Gainesville, Florida, USA.

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Intralesional biologics for inflammatory dermatoses: A systematic review.

Dermatol Ther 2022 02 8;35(2):e15234. Epub 2021 Dec 8.

Department of Dermatology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.

Biologic medications are systemic therapeutic options for inflammatory dermatoses. Local forms of administration are less well-studied. To provide a summary of intralesional (IL) administration of biologics for various non-malignant inflammatory dermatologic conditions reported in the literature. Read More

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February 2022

Successful Novel Treatment of Granuloma Faciale Using CO Emulated Er:YAG Laser Ablation.

Plast Reconstr Surg Glob Open 2021 Oct 7;9(10):e3847. Epub 2021 Oct 7.

Department of Plastic Surgery, St. Elizabeth Boardman Hospital, Boardman, Ohio.

Granuloma faciale is a rare, benign inflammatory skin disease that has multiple medical treatment modalities due to its frequent unresponsiveness to treatment. This skin disease presents as a single, well-demarcated red-brown to violaceous, raised lesion, most commonly on the face, in middle-aged White men. Its etiology is unknown; sun exposure is thought to have some implications in its formation. Read More

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October 2021

Intralesional rituximab treatment for atypical refractory granuloma faciale.

Ann Dermatol Venereol 2021 12 26;148(4):272-274. Epub 2021 Aug 26.

Dermatology Department, CHU Caen, 14033 Caen, France; Université de Caen Basse-Normandie, Faculté de médecine, 14000 Caen, France.

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December 2021

Extrafacial granuloma faciale presenting as an annular plaque of the scalp.

Int J Dermatol 2022 Apr 5;61(4):e144-e146. Epub 2021 Jul 5.

Dermatology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.

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Granuloma Faciale Involving the Tarsoconjunctival Surface of the Eyelid.

Ophthalmic Plast Reconstr Surg 2021 Jul-Aug 01;37(4):e148-e149

South Australian Institute of Ophthalmology, Royal Adelaide Hospital, Adelaide, South Australia, Australia.

We present the case of a Caucasian woman with a histology-confirmed granuloma faciale of the tarsoconjunctival surface of the eyelid. A 66-year-old female patient presented with a 1-week history of painless left upper eyelid mass without history of allergy, trauma, or ocular surgery. There was an elevated well-demarcated flesh-colored lesion within the tarsus. Read More

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Basal cell carcinoma associated with non-neoplastic cutaneous conditions: a comprehensive review.

Philip R Cohen

Dermatol Online J 2021 Feb 15;27(2). Epub 2021 Feb 15.

San Diego Family Dermatology, National City, CA Touro University California College of Osteopathic Medicine, Vallejo, CA.

Basal cell carcinoma (BCC) can be a component of a collision tumor in which the skin cancer is present at the same cutaneous site as either a benign tumor or a malignant neoplasm. However, BCC can also concurrently occur at the same skin location as a non-neoplastic cutaneous condition. These include autoimmune diseases (vitiligo), cutaneous disorders (Darier disease), dermal conditions (granuloma faciale), dermal depositions (amyloid, calcinosis cutis, cutaneous focal mucinosis, osteoma cutis, and tattoo), dermatitis, miscellaneous conditions (rhinophyma, sarcoidal reaction, and varicose veins), scars, surgical sites, systemic diseases (sarcoidosis), systemic infections (leischmaniasis, leprosy and lupus vulgaris), and ulcers. Read More

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February 2021

Rhinophyma-like granuloma faciale.

Dermatol Ther 2021 03 24;34(2):e14772. Epub 2021 Jan 24.

Department of Dermatology, Hospital do Meixoeiro EOXI, Vigo, Spain.

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[Association of borderline tuberculoid leprosy and tuberculosis: A case report and review of the literature].

Ann Dermatol Venereol 2020 Dec 27;147(12):886-891. Epub 2020 Oct 27.

Service de dermatologie, Hôpital Saint-Louis, Assistance Publique des Hôpitaux de Paris (AP-HP), 75010 Paris, France; Service d'anatomie et cytologie pathologique, Hôpital Saint-Louis, Assistance Publique des Hôpitaux de Paris (AP-HP), 75010 Paris, France.

Introduction: In metropolitan France, nearly 20 new cases of leprosy are diagnosed each year. The incidence of tuberculosis in France is 8/100,000 inhabitants and there are very few accounts of association of these two mycobacteria. Herein we report a case of co-infection with borderline tuberculoid (BT) leprosy and disseminated tuberculosis diagnosed in metropolitan France. Read More

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December 2020

Eosinophilic Dermatoses: Recognition and Management.

Am J Clin Dermatol 2020 Aug;21(4):525-539

Dermatology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

Eosinophilic dermatoses encompass a broad spectrum of diseases of different etiologies hallmarked by eosinophilic infiltration of the skin and/or mucous membranes, with or without associated blood eosinophilia. The wide range of dermatological manifestations of this spectrum, including nodules and plaques, pustules, blisters, ulcers, and urticarial lesions, is reflected in a non-univocal classification system. We identified six groups of eosinophilic dermatoses based on the predominant anatomic level of involvement: (1) epidermal; (2) of the dermal-epidermal junction; (3) dermal; (4) of the hypodermis and muscle fascia; (5) of the pilosebaceous unit; and (6) vascular/perivascular. Read More

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Granuloma faciale arising on a scar after Mohs surgery for basal cell carcinoma.

J Cosmet Dermatol 2020 Jul 16;19(7):1807-1809. Epub 2020 Mar 16.

Department of Pathology, School of Medicine, Hacettepe University, Ankara, Turkey.

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Harefuah 2020 Jan;159(1):34-37

Department of Dermatology, Emek Medical Center, Afula, Israel.

Aims: This study aims to critically review the pros and cons of biological drugs as treatments and triggers of eosinophilic dermatoses.

Background: Eosinophilic dermatoses syndromes are rare diseases with a prominent eosinophilic infiltration mechanism. These syndromes have several known treatments with limited success. Read More

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January 2020

[A case report of granuloma faciale, an uncommon cutaneous vasculitis].

Medwave 2019 Dec 6;19(11):e7740. Epub 2019 Dec 6.

Servicio de Anatomía Patológica, Hospital Clínico San Borja Arriarán, Santiago, Chile. ORCID: 0000-0002-3044-1849.

Granuloma faciale is an uncommon benign dermatosis, with unknown etiology, usually asymptomatic, characterized by chronic inflammation localized in sun-exposed areas of the face with a characteristic histological pattern. Although response to treatment is variable, there are multiple therapeutic alternatives that have been reported to be effective in some patients, including systemic treatments with steroids and dapsone or also topical treatments like intralesional corticosteroid, cryotherapy and calcineurin inhibitors, such as tacrolimus. We present the case of an adult patient with an asymptomatic erythematous-violet plaque on the right cheek, with progressive slow growth over two years, clinically and histologically and pathologically compatible with a facial granuloma. Read More

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December 2019

A case of granuloma faciale successfully treated with systemic dapsone.

Dermatol Ther 2020 01 17;33(1):e13162. Epub 2019 Nov 17.

Department of Dermatology and Venereology, Sapienza University of Rome, Rome, Italy.

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January 2020

Resolution of granuloma faciale with topical tacrolimus.

Int J Dermatol 2020 Feb 30;59(2):e29-e31. Epub 2019 Sep 30.

Dermatology Department, Hospital de Santarém EPE, Santarém, Portugal.

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February 2020

Eosinophilic dermatoses.

J Dtsch Dermatol Ges 2019 10 27;17(10):1039-1051. Epub 2019 Sep 27.

Department of Dermatology, University Hospital, Jena, Germany.

Eosinophilic dermatoses are a heterogeneous group of diseases, characterized by an eosinophil-rich infiltrate and/or degranulation of eosinophils. Blood eosinophilia may be an associated feature. Typical, albeit not specific histological findings include 'flame figures', which are caused by the accumulation of cationic proteins released by eosinophils and subsequent collagen denaturation. Read More

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October 2019

[Langerhans cell histiocytosis revealed by a temporomandibular joint disorder: Report of a case and review of the craniofacial expressions].

Rev Med Interne 2020 Jan 29;41(1):50-53. Epub 2019 Aug 29.

Service de chirurgie maxillo-faciale et stomatologie, centre hospitalo-universitaire de Rouen, 1, rue de Germont, 76000 Rouen, France; Laboratoire d'anatomie, faculté de médecine de Rouen, 22, boulevard Gambetta, 76000 Rouen, France; Institut national de la santé et de la recherche médicale (Inserm), LIMICS UMR-1142, 76000 Rouen, France. Electronic address:

Introduction: Langerhans cell histiocytosis (HL) is a rare disease that can affect all tissues. Oral manifestations such as mucosal ulcer and tooth mobility are often the first signs of the disease. We report a rare case of mandibular condyle unifocal HL mimicking a temporomandibular joint disorder. Read More

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January 2020

Granuloma Faciale Treated Successfully with Colchicine.

Acta Derm Venereol 2019 Jul;99(9):833-834

Department of Dermatology, Kurume University School of Medicine, 67 Asahimachi, Kurume, Fukuoka 830-0011, Japan.

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Molecular and cellular characterizations of human cherubism: disease aggressiveness depends on osteoclast differentiation.

Orphanet J Rare Dis 2018 09 20;13(1):166. Epub 2018 Sep 20.

INSERM, UMRS 1138 Equipe 5, Laboratoire de Physiopathologie Orale Moléculaire, Centre de Recherche de Cordeliers, 75006, Paris, France.

Background: Cherubism is a rare autosomal dominant disorder of the jaws caused by mutation of the SH3BP2 gene. The bone is replaced by a fibrous granuloma containing multinucleated giant cells. Cells of the cherubism granuloma have never been systematically analyzed. Read More

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September 2018

[Cutaneous foreign body granulomas following cervico-facial arterial embolization: Three cases].

Ann Dermatol Venereol 2018 Nov 11;145(11):659-664. Epub 2018 Sep 11.

Service de dermatologie, hôpital Saint-Joseph, 26, boulevard de Louvain, 13285 Marseille, France.

Background: Foreign body granuloma is an inflammatory tissue reaction to exogenous material. Classically it appears on the face after aesthetic procedures. Herein we report for the first time three cases of facial granulomatous reactions to microbeads after arterial cervico-facial embolization. Read More

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November 2018

Assessment of Treatment of Refractory Granuloma Faciale With Intralesional Rituximab.

JAMA Dermatol 2018 11;154(11):1312-1315

Department of Dermatology, Hospital Clínic de Barcelona, Universitat de Barcelona, Barcelona, Spain.

Importance: Granuloma faciale (GF) is a rare, benign inflammatory dermatosis of unknown cause. Some reports have suggested that it could be part of the spectrum of IgG4-related sclerosing diseases. Granuloma faciale is characterized by single or multiple red-brown nodules, most frequently occurring on the face, and it can produce severe disfigurement. Read More

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November 2018

Dermoscopy of granuloma faciale: a description of a new finding.

An Bras Dermatol 2018 Jul-Aug;93(4):587-589

Service of Dermatology, Hospital do Servidor Público Estadual de São Paulo, São Paulo (SP), Brazil.

Granuloma faciale is a rare, chronic dermatologic disorder, which mainly affects the face. Recently, dermoscopy has been demonstrated as an important ancillary tool on the clinical diagnosis of facial dermatoses. We report two cases of granuloma faciale with yellow areas on dermoscopy that was not yet described in the literature, corresponding to abundant hemosiderin on histopathological examination. Read More

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September 2018

Chronological observation of surgically-treated granuloma faciale implies the necessity of circumspect management for perinasal nodular subset.

J Dermatol 2018 Sep 15;45(9):1122-1125. Epub 2018 Jun 15.

Department of Dermatology, Kyorin University School of Medicine, Tokyo, Japan.

Granuloma faciale (GF) is a rare chronic dermatosis with still unknown etiopathology, which usually presents a solitary, asymptomatic, smooth reddish-brown to violaceous plaques or nodules on the face. Various therapeutic approaches, including topical application of corticosteroid or tacrolimus and removal with laser, cryotherapy and surgery have been attempted; however, the outcome has been inconsistent. Herein, we report a case of perinasal nodular GF who repeatedly underwent surgical excisions after the failure of laser treatment. Read More

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September 2018

Image Gallery: Concomitant eosinophilic angiocentric fibrosis and granuloma faciale.

Br J Dermatol 2018 06;178(6):e395

Department of Dermatology, Peking Union Medical College Hospital, Dongcheng District, Beijing, 100730,, China.

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[Extra-facial Lever granuloma on a herpes zoster scar: Wolf's isotopic response].

Ann Dermatol Venereol 2018 May 17;145(5):354-358. Epub 2018 Apr 17.

Service de dermatologie, CHR Metz-Thionville, 1, allée du Château, 57245 Ars-Laquenexy, France.

Background: Granuloma faciale (GF), or facial granuloma of Lever, is an uncommon dermatosis occurring classically on the face. We report a case of a GF on zoster scars located on the trunk, which is a highly particular isotopic response.

Patients And Methods: A 60-year-old man with a sole history of left lumbar zoster presented with a skin lesion present for two months. Read More

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A case of granuloma faciale successfully treated with oral prednisone, tranilast and thalidomide.

Postepy Dermatol Alergol 2018 Feb 20;35(1):109-112. Epub 2018 Feb 20.

Institute of Dermatology, Jiangsu Key Laboratory of Molecular Biology for Skin Diseases and STIs, Chinese Academy of Medical Science and Peking Union Medical College, Nanjing, China.

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February 2018

Cholesterol granuloma of the maxilla.

Morphologie 2018 Mar 13;102(336):41-43. Epub 2018 Feb 13.

Service de chirurgie maxillo-faciale et stomatologie, CHU d'Angers, 4, rue Larrey, 49933 Angers cedex, France; Groupe études remodelage osseux et biomatériaux (GEROM) - LHEA, IRIS-Institut de biologie en santé (IBS), université d'Angers, CHU d'Angers, 49933 Angers cedex, France. Electronic address:

Intra-osseous cholesterol granuloma (CG) is a rare and benign lesion. Very few cases of CG of the jaws have been described in the literature. CG of the jaws seems to be due to the accumulation of cholesterol of hematogenous origin in odontogenic cysts. Read More

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