1,672 results match your criteria Granuloma Annulare

Treatment of granuloma annulare with tofacitinib.

Australas J Dermatol 2022 May 23. Epub 2022 May 23.

Department of Dermatology, Hospital Clinic of Barcelona, University of Barcelona, Barcelona, Spain.

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Generalized Granuloma Annulare after COVID-19 vaccination.

JAAD Case Rep 2022 May 14. Epub 2022 May 14.

Department of Dermatology, Larkin Community Hospital, South Miami, Florida.

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Resolution of refractory generalized granuloma annulare after treatment with alitretinoin.

JAAD Case Rep 2022 Jun 14;24:38-41. Epub 2022 Apr 14.

Department of Dermatology, Seoul National University College of Medicine and Seoul Metropolitan Government Seoul National University Boramae Medical Center, Seoul, Korea.

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Granuloma annulare and necrobiosis lipoidica in a patient with -MODY.

Arch Endocrinol Metab 2022 May 12. Epub 2022 May 12.

Disciplina de Endocrinologia, Universidade Federal de São Paulo (Unifesp), São Paulo, SP, Brasil.

Maturity-onset diabetes of the young (MODY) is a heterogeneous group of monogenic forms of diabetes mellitus with distinct clinical features. Clinical dermatological phenotypes in MODY patients are very rare in literature. This report describes a patient with presenting with necrobiosis lipoidica (NL) and granuloma annulare (GA). Read More

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Treatment of generalized granuloma annulare with tildrakizumab.

Australas J Dermatol 2022 May 2. Epub 2022 May 2.

Sinclair Dermatology, East Melbourne, Victoria, Australia.

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Subtlety of Granulomatous Mycosis Fungoides: A Retrospective Case Series Study and Proposal of Helpful Multimodal Diagnostic Approach With Literature Review.

Am J Dermatopathol 2022 Apr 11. Epub 2022 Apr 11.

Department of Dermatopathology, Icahn School of Medicine at Mount Sinai, New York, NY.

Abstract: Granulomatous mycosis fungoides (GMF) harbors a worse prognosis compared with classic MF and remains a significant diagnostic dilemma. We analyzed clinicopathologic, immunophenotypic, and molecular characteristics of GMF to develop a diagnostic algorithm. Our methodology involved a retrospective case series study of patients with GMF from our database between 2014 and 2020. Read More

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The Clinical Presentation and Comorbidities Associated with Granuloma Annulare in the Pediatric Population: A Retrospective Study.

Skinmed 2022 28;20(1):24-28. Epub 2022 Feb 28.

2 Section of Dermatology, Departments of Medicine and Pediatrics, University of Chicago, Chicago, IL, USA.

Granuloma annulare (GA) is a cutaneous inflammatory disorder of unknown cause, typically characterized by an annular arrangement of dermal papules and nodules. While GA in adults has been linked to diabetes mellitus (DM) and other conditions, these associations have been less studied in children. A retrospective chart review was conducted of all pediatric patients diagnosed with GA at an urban academic institution over a 7-year period. Read More

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Rare Palisading Variant of Dermatofibroma.

Am J Dermatopathol 2022 Jun 6;44(6):439-441. Epub 2022 Apr 6.

Pathology, Kaiser Permanente Los Angeles, Medical Center, Los Angeles, CA.

Abstract: Dermatofibromas (DFs) are benign lesions that typically present as firm papules or nodules on the legs of young- to middle-aged adults. DFs are histologically characterized by a dermal proliferation of spindled fibrohistiocytic cells forming intersecting fascicles and showing collagen entrapment. The palisading variant of DF was first described in 1986 and often presents as a dome-shaped nodule on the digits. Read More

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The Immunogenetics of Granulomatous Diseases.

Adv Exp Med Biol 2022 ;1367:349-368

Department of Dermatology, Mersin University, Mersin, Turkey.

Non-infectious granulomatous skin diseases are a wide category of well-defined reactive inflammatory conditions that share main similarities. While cutaneous sarcoidosis is the prototype of non-infectious (sterile) granulomatous dermatitides, there are several other entities in this group including granuloma annulare and necrobiosis lipoidica. Non-infectious granulomatous diseases are caused by complex associations between genetic situations and environmental triggers resulting in a variety of cutaneous and systemic manifestations. Read More

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Interstitial Granulomatous Drug Reaction: A Case Report.

Cureus 2022 Feb 4;14(2):e21893. Epub 2022 Feb 4.

Dermatology Department, King Abdulaziz Hospital, Makkah, SAU.

Interstitial granulomatous drug reaction (IGDR) is a rare inflammatory reaction of the skin with an unknown etiology. Here, we report the case of a 55-year-old female with a history of diabetes mellitus and hypertension who presented with an asymptomatic persistent skin lesion over the left breast for more than one year. Skin examination revealed a single non-scaly, sharply demarcated, erythematous annular patch. Read More

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February 2022

Phototherapy in dermatological maladies (Review).

Exp Ther Med 2022 Apr 3;23(4):259. Epub 2022 Feb 3.

Department of Dermatology, 'Grigore T. Popa' University of Medicine and Pharmacy, 700115 Iasi, Romania.

Since the introduction of modern phototherapy in 1903 by Nobel Prize-winner Niels Ryberg Finsen, the usage of this therapy in the medical field has grown, techniques have been refined and developed, and it has gained widespread acceptance. Psoriasis vulgaris, parapsoriasis, lichen planus, atopic dermatitis, neonatal jaundice, urticaria, morphea, vitiligo, granuloma annulare and cutaneous T cell lymphoma are only a few dermatological indications that come along with satisfactory results. Most often, it is a 2nd or 3rd line therapy being an alternative in more severe or refractory diseases. Read More

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Periocular subcutaneous granuloma annulare in a child: A case report.

Am J Ophthalmol Case Rep 2022 Mar 24;25:101317. Epub 2022 Jan 24.

Oculoplasty, Dhahran Eye Specialist Hospital, Dhahran, Saudi Arabia.

Purpose: We describe a rare case of annular granuloma involving the eyelid of a child, a 6-year-old male, who presented with multiple subcutaneous nodular lesions involving the upper eyelid of the right eye.

Observations: The slit-lamp examination of the eye was normal. Extra-ocular examination showed a lesion on the dorsal aspect of the right foot, which was resistant to treatment with topical corticosteroids. Read More

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Successful treatment of generalized granuloma annulare with baricitinib.

J Eur Acad Dermatol Venereol 2022 07 3;36(7):e500-e502. Epub 2022 Mar 3.

Department of Dermatology, The Eighth Affiliated hospital of Sun Yat-sen University, Shenzhen, China.

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Erythematous brownish plaques with an annular configuration.

Clin Exp Dermatol 2022 May 23;47(5):995-998. Epub 2022 Feb 23.

Department of Dermatology, Coimbra University Hospital, Coimbra, Portugal.

Granuloma annulare (GA) and cutaneous sarcoidosis show clinicopathological overlap and they are also aetiopathogenically related. Given the similarities of sarcoidal GA and sarcoidosis, and the reports of association of sarcoidal GA with systemic sarcoidosis, this diagnosis should prompt further investigation to exclude systemic involvement. Being aware of the subtle histopathological clues is of the utmost importance for an accurate diagnosis of this rare variant, but correlation with the clinical setting and use of ancillary investigations are also warranted to confidently exclude sarcoidosis. Read More

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Generalized granuloma annulare resolution following biopsy: a remote reverse Koebner phenomenon.

Clin Exp Dermatol 2022 Jun 3;47(6):1194-1195. Epub 2022 Apr 3.

Department of Pathology, Amrita Institute of Medical Sciences and Research Centre, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India.

This generalized granuloma annulare case of palisading type, with extensive lesions of 10 months duration resolving 1 week post biopsy without any treatment is the most exceptional depiction of this poorly understood remote reverse Koebner phenomenon. Read More

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Eruptive Granuloma Annulare in an Elderly Man With Diabetes.

Cureus 2022 Jan 14;14(1):e21242. Epub 2022 Jan 14.

Department of Dermatology, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, SAU.

Although the etiology of granuloma annulare (GA) remains unknown, it has been associated with many reported triggers, including chronic medical illnesses and malignancy. Herein, we present a case of an elderly man with diabetes who has a generalized variant of granuloma annulare. The patient had a six-month history of multiple skin-colored, scattered, itchy papules disseminated over the trunk. Read More

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January 2022

The case of granuloma annulare associated with SARS-CoV-2 infection.

Dermatol Ther 2022 May 16;35(5):e15369. Epub 2022 Feb 16.

Department of Pathology, Ankara Yıldırım Beyazıt University, Medical School, Ankara, Turkey.

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Off-label uses of TNF-a inhibitors and IL-12/23 inhibitors in dermatology.

Dermatol Online J 2021 Nov 15;27(11). Epub 2021 Nov 15.

University of California San Francisco, Department of Dermatology, Psoriasis and Skin Treatment Center.

TNF-a inhibitors, which include adalimumab, infliximab, etanercept, certolizumab, and golimumab, and IL-12/23 inhibitor, ustekinumab, have been widely used as a U.S. Food and Drug Administration (FDA) approved for the treatment of psoriasis. Read More

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November 2021

Remote Reverse Koebner Phenomenon in Atypical Granuloma Annulare.

Indian J Dermatol 2021 Sep-Oct;66(5):551-552

Department of Obstetrics and Gynaecology, Government Medical College, Barmer, Rajasthan, India E-mail:

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January 2022

Pleomorphic Appearance of Breast Cancer Cutaneous Metastases.

Philip R Cohen

Cureus 2021 Dec 9;13(12):e20301. Epub 2021 Dec 9.

Dermatology, University of California, Davis Medical Center, Sacramento, USA.

Cutaneous metastases occur in approximately 10% of oncology patients as a feature of a persistent solid tumor or the harbinger of recurrent neoplastic disease. However, they can be the presenting manifestation of an unsuspected visceral malignancy in one percent of previously cancer-free individuals. Metastatic skin lesions from breast carcinoma are diverse in their appearance. Read More

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December 2021

Generalized Granuloma Annulare Successfully Treated with Ustekinumab.

J Clin Aesthet Dermatol 2021 Oct;14(10):17-18

Dr. Song is with North Sound Dermatology in Mill Creek, Washington.

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October 2021

Exploring the association between granuloma annulare and severity of type 2 diabetes in a large administrative database.

J Am Acad Dermatol 2021 Dec 30. Epub 2021 Dec 30.

Department of Dermatology, Brigham and Women's Hospital, Boston, Massachusetts.

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December 2021

Generalized granuloma annulare: Narrow-band UVB phototherapy combined with tacrolimus ointment.

Dermatol Ther 2022 02 15;35(2):e15250. Epub 2021 Dec 15.

SSD Dermatologia e Allergologia, Ospedale Beauregard, Aosta, Italy.

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February 2022

An evidence-based approach for malignancy-associated and paraneoplastic generalized granuloma annulare.

J Am Acad Dermatol 2021 Dec 4. Epub 2021 Dec 4.

Department of Dermatology, Wayne State University, Detroit, Michigan. Electronic address:

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December 2021

Light- and laser-based treatments for granuloma annulare: A systematic review.

Photodermatol Photoimmunol Photomed 2021 Dec 7. Epub 2021 Dec 7.

Department of Dermatology and Skin Science, University of British Columbia, Vancouver, British Columbia, Canada.

Background: Granuloma annulare (GA) is challenging to treat, especially when generalized. A systematic review to support the use of light- and laser-based treatments for GA is lacking.

Methods: We performed a systematic review by searching Cochrane, MEDLINE, and Embase. Read More

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December 2021

Paraneoplastic Granuloma Annulare Associated with Metastatic Lung Cancer.

Skinmed 2021 1;19(5):387-389. Epub 2021 Oct 1.

Department of Basic Medical Sciences at the University of Arizona College of Medicine-Phoenix, AZ.

A 60-year-old Caucasian woman with a 15-year smoking history presented with new, asymptomatic, pink lesions that gradually appeared over a period of 6 weeks. Physical examination revealed erythematous annular and nummular plaques on her upper and lower extremities, chest, and abdomen (Figure 1A and 1B). A shave biopsy from the right thigh revealed focal areas of necrobiotic collagen in the superficial portion of the dermis, surrounded by histiocytes, multinucleated giant cells, and lymphocytes, consistent with granuloma annulare (GA) (Figure 2). Read More

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January 2022

Hydroxychloroquine: An Essential Drug in Dermatology and Its Controversial Use in COVID-19.

Actas Dermosifiliogr 2021 Nov 26. Epub 2021 Nov 26.

Dermik, Clínica Dermatológica Multidisciplinar, Barcelona, Spain.

Hydroxychloroquine is an antimalarial drug with immunomodulatory, anti-inflammatory, antibacterial, and antiviral properties. It has a good safety profile, can be used in children and in pregnant and breastfeeding women, and does not suppress the immune system. Regular screening for retinopathy, one of the drug's most feared adverse effects, is necessary. Read More

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November 2021