J Am Podiatr Med Assoc 2008 Jan-Feb;98(1):42-4

Department of Dermatology, Afyon Kocatepe University, School of Medicine, Afyon, Turkey.

Background: Foot intertrigo, occurring in the interdigital space, is mostly caused initially by dermatophytes and yeasts and less frequently by gram-negative and gram-positive bacteria. With time, a "complex" may develop in the setting of moisture and maceration that contains multiple fungal and bacterial organisms.

Methods: We examined and sampled 84 patients with toe web intertrigo for bacteriologic and mycologic studies. Read More

Arch Dermatol 2005 May;141(5):658

Duke University Medical Center, Durham, NC, USA.

J Am Acad Dermatol 2001 Oct;45(4):537-41

Dermatology Department, Cagliari University Hospital San Giovanni di Dio, Cagliari, Italy.

Background: Foot intertrigo is mostly caused by dermatophytes and yeasts, less frequently by gram-positive and gram-negative bacteria. Nevertheless, the importance of polymicrobial infections and especially colonizations of Pseudomonas aeruginosa can cause therapy problems in relation to antibiotic resistance and the risk of potentially lethal complications.

Objective: The aim of this study was to evaluate the main epidemiologic and clinical features of intertrigo from gram-negative bacteria, the function of promoting factors, and the measures taken to treat and prevent this disorder. Read More

J Am Acad Dermatol 1990 Apr;22(4):583-6

Department of Dermatology, School of Medicine, University of Pennsylvania, Philadelphia.

Twenty-four patients with severe interdigital toe web infections and no evidence of dermatophyte colonization received randomized treatment with either econazole nitrate (Spectazole) or its vehicle. Of the patients treated with econazole nitrate, 88% had good to excellent responses, whereas no patient treated with the vehicle showed improvement. The total aerobic flora in the econazole group decreased 93%, with decreases in the large-colony diphtheroids, lipophilic diphtheroids, and gram-negative bacteria. Read More

J Med Assoc Thai 1989 Jul;72 Suppl 2:33-8

Bacterial colonization was studied in 12 non-infected female patients admitted into one medical ward, Siriraj hospital, Bangkok, from March to June 1988. Swabs were taken on the first day of admission, then every other day until discharge, from six sites; i.e. Read More

Z Hautkr 1988 Nov;63(11):958-65

Zentrum für Dermatologie, Andrologie und Venerologie, Abt. klin. u. exp. Dermatologie, Justus-Liebig-Universität Giessen.

Referring to recent studies, we discuss the epidemiology of tinea pedis and its position within the range of polyetiological foot infections caused by microbial agents. 201 industrial workers used to wear rubber boots because of moist working conditions were examined with regard to their feet. 107 of them showed clinically altered toe web; in 45 cases, we found ringworm infection (22. Read More

J Am Acad Dermatol 1986 Feb;14(2 Pt 1):278-9

J Am Acad Dermatol 1983 Feb;8(2):225-8

Fifteen patients with gram-negative bacterial toe web infections were treated for 1 week with intramuscular cefoperazone, a broad-spectrum third generation cephalosporin. Initial bacterial cultures in eleven patients (73%) grew more than one gram-negative organism. Pseudomonas aeruginosa was the most frequent isolate. Read More