17,251 results match your criteria Gout and Pseudogout


Gout in the Gilded Age: The Case of Richard Morris Hunt.

Authors:
Robert S Pinals

J Clin Rheumatol 2018 Dec 5. Epub 2018 Dec 5.

From the Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ.

Richard Morris Hunt, a distinguished American architect of the late 19th century (the Gilded Age), had onset of gout at age 41 years. His attacks became more frequent and severe, eventually leading to chronic pain and disability. His medical care by highly regarded physicians resulted in very limited benefit, but through his dedication and work ethic, he remained productive until his death at age 67 years. Read More

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December 2018

Knowledge and practice in the management of asymptomatic hyperuricemia among primary health care physicians in Jeddah, Western Region of Saudi Arabia.

Saudi Med J 2018 Dec;39(12):1218-1225

Joint Program of Family Medicine, King Fahad Armed Forces Hospital, Jeddah, Kingdom of Saudi Arabia. E-mail.

Objectives: To assess knowledge and practice levels in asymptomatic hyperuricemia (AH) and investigate predictors of urate-lowering therapy (ULT) misprescribing among primary health care (PHC) physicians.

Methods: A cross-sectional study was conducted among 201 PHC physicians from December 2017 to May 2018. A based clinical guidelines for hyperuricemia management from American Professional Organizations, a semi-structured questionnaire was administered to collect demographic and professional data; knowledge and practice levels in management of AH; and barriers to the management of hyperuricemia and gout, with focus of the misprescribing of ULT in AH. Read More

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December 2018

Does interindividual variability of saliva affect the release and metabolisation of aroma compounds ex-vivo? The particular case of elderly suffering or not from hyposalivation.

J Texture Stud 2018 Dec 5. Epub 2018 Dec 5.

Centre des Sciences du Goût et de l'Alimentation, UMR1324 INRA, UMR6265 CNRS Université de Bourgogne, Agrosup Dijon, F-21000 Dijon, France.

The aim of this work was to study the effects of interindividual variability of human elderly saliva on aroma release and metabolisation by ex vivo approaches. Thirty individuals suffering or not from hyposalivation were selected from a panel formed by 110 elderly people (aged >65 years old) that were matched by age and sex. Then, their stimulated saliva samples were independently incubated in presence of three aroma compounds (ethyl hexanoate, octanal, 2-nonanone) to perform headspace-gas chromatography (HS-GC) and liquid/liquid extraction-gas chromatography mass spectrometry (LLE-GC/MS) analyses. Read More

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December 2018

How Would You Manage This Patient With Gout?: Grand Rounds Discussion From Beth Israel Deaconess Medical Center.

Ann Intern Med 2018 Dec;169(11):788-795

Beth Israel Deaconess Medical Center, Boston, Massachusetts (R.B.B., C.C.S., R.H.S., A.T.).

Gout is the most common form of inflammatory arthritis. In 2012, the American College of Rheumatology (ACR) issued a guideline, which was followed in 2017 by one from the American College of Physicians (ACP). The guidelines agree on treating acute gout with a corticosteroid, nonsteroidal anti-inflammatory drug, or colchicine and on not initiating long-term urate-lowering therapy (ULT) for most patients after a first gout attack and in those whose attacks are infrequent (<2 per year). Read More

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December 2018

Antioxidant and xanthine oxidase inhibitory activities of total polyphenols from onion.

Saudi J Biol Sci 2018 Nov 18;25(7):1509-1513. Epub 2017 Aug 18.

School of Materials Science and Engineering, Central South University of Forestry and Technology, Changsha 410004, China.

Onions ( L.) comprise a valuable vegetable crop in many countries. Modern scientific research has shown that onions possess many biological activities, including antibacterial, anticancer, hypoglycemic, hypolipidemic, antiplatelet aggregation, and antioxidant activities. Read More

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November 2018

A Pharmacist-Led Intervention to Improve Gout Medication Adherence and Outcomes with Urate Lowering Therapy: A Site Randomized Trial.

Am J Med 2018 Nov 29. Epub 2018 Nov 29.

Division of Rheumatology, University of Alabama at Birmingham, Birmingham, AL.

Purpose: To test a pharmacist-led intervention to improve gout treatment adherence and outcomes.

Methods: We conducted a site-randomized trial (n=1,463 patients) comparing a one-year, pharmacist-led intervention to usual care in gout patients initiating allopurinol. The intervention was delivered primarily through automated telephone technology. Read More

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November 2018

Impact of Non-Adherence and Flare Resolution on the Cost-Effectiveness of Treatments for Gout: Application of a Linked Pharmacometric/Pharmacoeconomic Model.

Value Health 2018 Dec 26;21(12):1373-1381. Epub 2018 Jul 26.

Centre for Health Economics and Medicines Evaluation, Bangor University, Bangor, UK. Electronic address:

Background: Dual urate-lowering therapy (ULT) with lesinurad in combination with either allopurinol or febuxostat is an option for patients with gout unsuccessfully treated on either monotherapy. Treatment failure is often a result of poor medication adherence. Imperfect adherence in clinical trials may lead to biased estimates of treatment effect and confound the results of cost-effectiveness analyses. Read More

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December 2018

ASSOCIATION OF DYSADIPOKINEMIA WITH TLR4 SERUM CONCENTRATION IN GOUT PATIENTS.

Georgian Med News 2018 Oct(283):59-62

National Pirogov Memorial Medical University, Vinnytsya, Ukraine.

Study objective was to estimate the levels of TLR4 in gout patients and evaluate their association with the dysadipokinemia. The study involved 65 gout patients and 24 healthy individuals. All study subjects proceeded clinical and laboratory examination. Read More

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October 2018

Effectiveness of healthcare educational and behavioral interventions to improve gout outcomes: a systematic review and meta-analysis.

Ther Adv Musculoskelet Dis 2018 Dec 19;10(12):235-252. Epub 2018 Nov 19.

Division of Clinical Immunology and Rheumatology, University of Alabama, Birmingham VA Medical Center, Faculty Office Tower 805B, 510 20th Street South, Birmingham, AL, 35294, USA.

Background: We aimed to systematically review the effectiveness of healthcare behavioral and education interventions for gout patients on clinical outcomes.

Methods: We searched multiple databases to identify trials or observational studies of educational or behavioral interventions in gout. Risk of bias was assessed with the Cochrane tool for randomized control trials (RCTs) and the Newcastle-Ottawa Scale for observational studies. Read More

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December 2018
1 Read

Sclérose en plaques et vaccins : quels risques ?

Authors:
Olivier Gout

Rev Prat 2015 Nov;65(9):1127-1129

Service de neurologie, Fondation ophtalmologique A. de Rothschild, Paris, France.

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November 2015

Un gain d’efficacité mais des effets indésirables parfois graves.

Rev Prat 2016 Jan;66(1):44-50

Service de neurologie, Fondation ophtalmologique Adolphe-de-Rothschild, Paris, France.

New treatments and strategy in multiple sclerosis. Currently, ten drugs are approved for the relapsing-remitting form of multiple sclerosis (MS). Since 2007, 4 new disease-modifying therapies (DMT) have been approved and several DMT will soon be commercialized including new galenic forms of self-injectable DMTs (pegylated interferon beta 1a and glatiramer acetate). Read More

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January 2016

Sclérose en plaques.

Authors:
Olivier Gout

Rev Prat 2016 Jan;66(1):31

Service de neurologie, Fondation ophtalmologique Adolphe de Rothschild, Paris, France.

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January 2016

[A woman with a white skin lesion of her toe].

Ned Tijdschr Geneeskd 2018 11 27;163. Epub 2018 Nov 27.

Huisartsenpraktijk Vondelplein, Amersfoort.

A 78-year-old woman visited her general practitioner with a sharply bounded white lesion of her toe. We diagnosed it as gouty tophus, which was confirmed by a high serum urate level. Gout is a chronic disease, characterised by deposition of monosodium urate crystals in joints and tissues. Read More

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November 2018
3 Reads

Inquiry Concerning Cold Water in Gout.

Authors:
William Norman

Lond Med Phys J 1816 Mar;35(205):203

Langport, Somerset.

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On the Cooling Treatment of Gout.

Authors:
Robert Kinglake

Lond Med Phys J 1815 Jul;34(197):6-10

Taunton.

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On the Effects of Tincture of Colchicum in Gout.

Authors:
John Lignum

Lond Med Phys J 1815 Apr;33(194):264-265

Member of the Royal College of Surgeons in London. Manchester.

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Theory of Gout.

Authors:

Med Phys J 1814 Jan;31(179):15-17

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January 1814

Additional Cases Illustrating the Modus Operandi of Colchicum in the Cure of Gout.

Authors:
John Want

Med Phys J 1814 Dec;32(190):491-493

Surgeon to the Northern Dispensary. North Crescent.

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December 1814

Case of the Paroxysm of Gout Removed by the Tincture of Colchicum.

Authors:
John Want

Med Phys J 1814 Oct;32(188):312-314

Surgeon to the Northern Dispensary. North Crescent.

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October 1814

Cases Illustrative of the Modus Operandi of Colchicum in the Cure of Gout.

Authors:
John Want

Med Phys J 1814 Nov;32(189):393-395

Surgeon to the Northern Dispensary. North Crescent.

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November 1814

Mr. Freake on the Use of Humulus in Gout.

Authors:

Med Phys J 1813 Apr;29(170):294-296

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Mr. Want, on the Treatment of Gout.

Authors:
John Want

Med Phys J 1811 Sep;26(151):188-203

Surgeon to the Northern Dispensary.

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September 1811

Mr. Ring on Cathartics in Gout.

Authors:
J Ring

Med Phys J 1811 Nov;26(153):380-382

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November 1811

Dr. Harrison, on Ginger in Rheumatic Gout.

Authors:
J E Harrison

Med Phys J 1808 Jun;19(112):527-528

Thornbury 11 Miles from Bristol.

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Observations on Cold Water in Gout.

Authors:

Med Phys J 1808 Jun;19(112):535-538

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Dr. Kinglake, in Reply to Verax, on Gout.

Authors:
Robert Kinglake

Med Phys J 1808 Jul;20(113):65-69

Taunton.

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Dr. Kinglake, in Reply to Mr. Pope, on the Gout.

Authors:
Robert Kinglake

Med Phys J 1807 Sep;18(103):240-242

Taunton.

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September 1807

On the Treatment of Gout.

Authors:

Med Phys J 1807 Aug;18(102):163-169

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Mr. Pope, on Dr. Kinglake's Treatment of Gout.

Authors:
T Pope

Med Phys J 1807 Jul;18(101):52-55

Cleobury, Salop.

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Mr. Mantal, in Reply to Dr. Kinglake, on Gout.

Authors:
James Mantal

Med Phys J 1805 Dec;14(82):497-506

Bromley, High Elms.

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December 1805

Mr. Shearly's Case of Gout.

Authors:
William Shearly

Med Phys J 1805 Aug;14(78):120-122

Member of the Royal College of Surgeons, London. Royal Naval Hospital, Deal.

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Mr. Mantal, in Reply to Dr. Kinglake, on Gout.

Authors:

Med Phys J 1805 Nov;14(81):455-461

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November 1805

Dr. Kinglake, in Reply to Mr. Mantal, on Gout.

Authors:
Robert Kinglake

Med Phys J 1805 Sep;14(79):215-226

Taunton.

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September 1805

Mr. Mantal, on Gout.

Authors:
James Mantal

Med Phys J 1804 Dec;12(70):500-503

Bromley High Elms.

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December 1804

On Gout.

Authors:

Med Phys J 1804 Sep;12(67):216-219

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September 1804

Dr. Blegborough, on Gout.

Med Phys J 1804 Oct;12(68):375-380

Margaret Street.

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October 1804

Dr. Blegborough, on the Gout.

Med Phys J 1804 Jul;12(65):62-68

Margaret Street, Cavendish Square.

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