Search our Database of Scientific Publications and Authors

I’m looking for a

    36316 results match your criteria Goiter

    1 OF 727

    Metformin and thyroid disease.
    J Endocrinol 2017 Feb 14. Epub 2017 Feb 14.
    C Liu, Endocrinology, Jiangsu Province Hospital of Integration on Chinese and Western Medicine, Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing University of Traditional Chinese Medicine, Nanjing, China
    An intriguing area of research in thyroidology is the recently discovered association of insulin resistance with thyroid functional and morphological abnormalities. Individuals with hyperinsulinemia have larger thyroid gland and a higher prevalence of thyroid nodules and cancer. Accordingly, patients treated with metformin have a smaller thyroid volume and a lower risk of incident goiter, thyroid nodule and cancer. Read More

    Primary Thyroid Lymphoma: Clinicopathologic Characteristics and Therapeutic Outcomes of Six Cases in Morocco.
    • Authors:
    Gulf J Oncolog 2016 Sep;1(22):11-15
    Background: Primary non-Hodgkin lymphomas of the thyroid are uncommon and account for 1-5% of all thyroid malignancies and less than 2% of extranodal lymphomas. The aim of the present study was to review our experience and management of primary thyroid lymphoma and to discuss the diagnostic and therapeutic considerations.

    Methods: All non-Hodgkin lymphoma diagnosed at our institution between 2007 and 2011 were reviewed, six cases of primary thyroid lymphoma were identified. Read More

    Diffuse Follicular Variant of Papillary Thyroid Carcinoma: A Case Report with a Revision of Literature.
    Rare Tumors 2016 Nov 20;8(4):6536. Epub 2016 Dec 20.
    Department of Pathology, Sant'Andrea Hospital, University Sapienza of Rome , Italy.
    The diffuse follicular variant of papillary thyroid carcinoma (DFV-PTC) is a rare malignant thyroid condition. It represents an uncommon variant of papillary carcinoma characterized by a diffuse involvement of thyroid parenchyma, follicular architecture and nuclear features of PTC in absence of a surrounding capsule. Up to date few data have been collected about this entity and, at the best of our knowledge, only 24 cases have been reported in the literature. Read More

    Low Iodine in the Follicular Lumen Caused by Cytoplasm Mis-localization of Sodium Iodide Symporter may Induce Nodular Goiter.
    Biol Trace Elem Res 2017 Feb 12. Epub 2017 Feb 12.
    Department of Endocrinology, The Second Affiliated Hospital of Fujian Medical University, No. 34 North Zhongshan Road, Quanzhou, Fujian, 362000, People's Republic of China.
    Iodine is a key ingredient in the synthesis of thyroid hormones and also a major factor in the regulation of thyroid function. A local reduction of iodine content in follicular lumen leads to overexpression of local thyroid-stimulating hormone receptor (TSHr), which in turn excessively stimulates the regional thyroid tissue, and result in the formation of nodular goiter. In this study, we investigated the relationship between iodine content and sodium iodide symporter (NIS) expression by using the clinical specimens from patients with nodular goiter and explored the pathogenesis triggered by iodine deficiency in nodular goiter. Read More

    Perioperative determinants of transient hypocalcemia after pediatric total thyroidectomy.
    J Pediatr Surg 2017 Jan 27. Epub 2017 Jan 27.
    Division of Pediatric Surgery, Department of Surgery, Texas Children's Hospital and Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX 77030. Electronic address:
    Purpose: We seek to identify risk factors associated with hypocalcemia after pediatric total thyroidectomy.

    Methods: We retrospectively reviewed patients younger than 21years undergoing total thyroidectomy between January 2002 and January 2016. We defined hypocalcemia as any serum calcium <8mg/dl or ionized calcium <1. Read More

    How "suspicious" is that nodule? Review of "suspicious" Afirma gene expression classifier in high risk thyroid nodules.
    Diagn Cytopathol 2017 Feb 11. Epub 2017 Feb 11.
    Department of Pathology, Hofstra Northwell Health School of Medicine, Lake Success, New York.
    Background: The Afirma gene expression classifier (GEC) is being increasingly utilized to confirm the benign nature of indeterminate FNA cytology results thus avoiding unnecessary surgical procedures. However the "suspicious" result of the Afirma GEC does not classify these indeterminate nodules further in determining appropriate management. This study investigated the outcome of the thyroid nodules deemed to be "suspicious" by the Afirma GEC in a high risk population. Read More

    Transoral Endoscopic Thyroidectomy Vestibular Approach (TOETVA): From A to Z.
    Surg Technol Int 2017 Feb 7;30. Epub 2017 Feb 7.
    Minimally Invasive and Endocrine Surgery Division, Department of Surgery Police General Hospital, Bangkok, Thailand.
    We depict the transoral endoscopic thyroidectomy vestibular approach (TOETVA). Patient selection criteria are (1) ultrasonographically (US) estimated thyroid diameter no larger than 10cm, (2) US estimated gland volume ≥45mL, (3) nodule size ≥5mm, (4) a benign tumor, such as a thyroid cyst, single-nodular goiter, or multinodular goiter, (5) follicular neoplasm, and (6) papillary microcarcinoma without evidence of metastasis. TOETVA is carried out through a three-port technique placed at the oral vestibule, one 10mm port for 30° endoscope and two additional 5mm ports for dissecting and coagulating instruments. Read More

    Association between single nucleotide variants of vascular endothelial growth factor a and the risk of thyroid carcinoma and nodular goiter in a Han Chinese population.
    Oncotarget 2017 Feb 2. Epub 2017 Feb 2.
    Department of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun 130021, China.
    The aim of the present study was to investigate whether genetic variants in the vascular endothelial growth factor A gene (VEGFA) were risk factors for papillary thyroid carcinoma (PTC) or nodular goiter (NG) in Han Chinese. A total of 2,319 subjects (861 PTC patients, 562 NG patients, and 896 healthy controls) were included. Five tag single nucleotide polymorphisms (tagSNPs: rs3024997, rs3025040, rs833070, rs25648, and rs10434) in VEGFA were genotyped. Read More

    Anaplastic thyroid carcinoma and foscarnet use in a multitarget treatment documented by 18F-FDG PET/CT: A case report.
    Medicine (Baltimore) 2017 Feb;96(6):e5621
    aDepartment of Experimental Medicine bDepartment of Internal Medicine and Clinical Specialities cDepartment of Radiology, Anatomopathology and Oncology, Sapienza University of Rome, Rome dNuclear Medicine Unit, Department of Interventional Oncology, Azienda Ospedaliera Ospedale di Circolo di Busto Arsizio Varese, Busto Arsizio, Varese, Italy.
    Rationale: The case reported the rapid remission of disease recurrence achieved adding foscarnet, a DNA polymerase inhibitor that interacts with fibroblast growth factor 2, to low molecular weight heparin and sunitinib for the first time in a patient with an anaplastic thyroid cancer (ATC).

    Patient Concerns: A 65-year-old woman with a multinodular goiter referred for a rapid enlargement of a nodule. Histological examination revealed an ATC with a little area of papillary thyroid cancer (PTC). Read More

    Treatment of an aortic arch aneurysm with scalloped and fenestrated thoracic stent-graft and left carotid to subclavian artery bypass.
    Ann Vasc Surg 2017 Feb 2. Epub 2017 Feb 2.
    Department of Vascular Surgery, Singapore General Hospital. Electronic address:
    We report a successful treatment of thoracic arch aneurysm using a combination of hybrid approach and a customized stent graft in a frail patient with challenging anatomy and concomitant large retrosternal goiter. The patient is an 82-year-old lady with multiple comorbidities who presented to her general practitioner for anorexia and significant weight loss. She was incidentally found to have a 6. Read More

    [Epidemiological, clinical, therapeutic and evolutive aspects of Basedow-Graves disease in the Depatment of Internal Medicine at CHU Aristide Le Dantec, Dakar (Senegal)].
    Pan Afr Med J 2016 14;25. Epub 2016 Sep 14.
    Médecine Interne, Centre Hospitalier Universitaire Aristide Le Dantec, Dakar, Sénégal.
    Basedow-Graves disease is an autoimmune affection characterized by the association of thyrotoxicosis with variable frequency events such as goiter, ophthalmopathy and pretibial myxedema. Its diagnosis is often easy, while its management remains difficult. A simple medical treatment exposes patient to recurrence risk. Read More

    Trans-oral glasses-free three-dimensional endoscopic thyroidectomy-preliminary single center experiences.
    Gland Surg 2016 Dec;5(6):628-632
    Department of Thoracic Surgery, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou 510120, China.
    Glass-free three-dimensional (3D) endoscopic provide excellent depth perception without decreasing light quality and fog formation. Herein we report our first case-serial of trans-oral endoscopic thyroidectomy by means of our newly developed glasses-free 3D endoscopic system. Four patients with thyroid goiter undergone trans-oral glasses-free 3D endosocpic thyroidectomy were reviewed. Read More

    Transoral endoscopic thyroidectomy via vestibular approach: operative steps and video.
    Gland Surg 2016 Dec;5(6):625-627
    Department of Surgery, Police General Hospital, Faculty of Medicine, Siam University, Pathumwan, Bangkok, Thailand.
    In this video we describe transoral endoscopic thyroidectomy vestibular approach (TOETVA). Inclusion criteria are (I) patients who had a ultrasonographically (US) estimated thyroid diameter not larger than 10 cm; (II) US estimated gland volume ≤45 mL; (III) nodule size ≤50 mm; (IV) a benign tumor, such as a thyroid cyst, single-nodular goiter, or multinodular goiter; (V) follicular neoplasm; (VI) papillary microcarcinoma without evidence of metastasis. The procedure is carried out through three-port technique placed at the oral vestibule, one 10-mm port for 30° endoscope and two additional 5-mm ports for dissecting and coagulating instruments. Read More

    Evaluation of thyroid lesions by fine-needle aspiration cytology based on Bethesda system for reporting thyroid cytopathology classification among the population of South Bihar.
    Indian J Med Paediatr Oncol 2016 Oct-Dec;37(4):265-270
    Department of Pathology, Patna Medical College and Hospital, Patna, Bihar, India.
    Background: Fine-needle aspiration (FNA) of the thyroid gland has proven to be an important and widely accepted, cost-effective, simple, safe, and accurate method triaging patients with thyroid nodules. Awareness and understanding of wide spectrum thyroid disorders are of great value because most lesions are treatable by medical or surgical management.

    Aim: The aim of this study is to determine the accuracy of FNA cytology (FNAC) in the diagnosis of thyroid lesion using the Bethesda system for reporting thyroid cytopathology nomenclature (BSRTC) and to correlate these with histopathological findings. Read More

    Early Predictors of Post - Thyroidectomy Hypoparathyroidism.
    Pol Przegl Chir 2016 Dec;88(6):305-314
    Thyroid surgery is the most commonly performed procedure in the field of endocrine surgery. Studies are still ongoing on the development of a single algorithm for diagnosis and care of patients at risk of postoperative hypoparathyroidism. The aim of the study was to determine the biochemical marker that would allow the most accurate diagnosis of patient groups at risk of developing hypoparathyroidism and to identify risk factors for this disorder. Read More

    Vasorelaxant and cardiovascular properties of the essential oil of Pogostemon elsholtzioides.
    J Ethnopharmacol 2017 Jan 26. Epub 2017 Jan 26.
    School of Chemical and Biotechnology, SASTRA University, Thanjavur 613401, Tamil Nadu, India. Electronic address:
    Ethnobotanical Relevance: Pogostemon elsholtzioides Benth. (Lamiaceae) is an aromatic shrub, endemic to eastern Himalaya region. The leaves are used for treating goiter and high blood pressure (BP) by indigenous people in Arunachal Pradesh, India. Read More

    Limited cutaneous systemic sclerosis arising in a patient with Graves' disease.
    BMJ Case Rep 2017 Jan 27;2017. Epub 2017 Jan 27.
    Department of Medicine, University of the Philippines-Philippine General Hospital, Manila, Philippines.
    Although Graves' disease and systemic sclerosis are both autoimmune disorders, their relationship is rarely reported. We present the case of a Filipino woman with goitre and thyrotoxic signs and symptoms. Diagnosed with Graves' disease at the outpatient clinic, she took antithyroid medications and underwent radioactive iodine ablation with resultant hypothyroidism after 6 months, during which she began to experience skin tightness over the face, neck and fingers. Read More

    Prevalence of thyroid disorders in elderly people in Germany. A screening study in a country with endemic goitre.
    Nuklearmedizin 2017 Feb 26;56(1):9-13. Epub 2017 Jan 26.
    Prof. Dr. Markus Luster, University Hospital Marburg, Department of Nuclear Medicine, Baldingerstraße, 35043 Marburg Tel: +49-6421-5862815, Fax: +49-6421-5867025, E-Mail:
    Aim: In a screening study on people of working age the prevalence of morphological thyroid disorders was 33.1 %. It is not known precisely whether this further increases after retirement. Read More

    Otorhinolaryngology/Head and Neck Surgery in a low income country: The Haitian experience.
    Int J Pediatr Otorhinolaryngol 2017 Feb 30;93:128-132. Epub 2016 Dec 30.
    Department of Otolaryngology/Head & Neck Surgery, Stanford University, Stanford, CA, USA.
    Objective: Little is known regarding the diagnosis and management of pediatric surgical conditions of the head and neck in low-income countries. Haiti, the western hemisphere's poorest country, recently developed its first Otorhinolaryngology (ORL) department at the Hopital de L'Universite d'Etat d'Haiti (HUEH). This manuscript assesses the caseload at HUEH with a special emphasis on pediatric cases, with the aim of characterizing ORL related conditions and their treatments in low-income countries. Read More

    Role Of Iodine In Metabolism.
    Recent Pat Endocr Metab Immune Drug Discov 2017 Jan 19. Epub 2017 Jan 19.
    Chair and Department of Endocrinology, Jagiellonian University Collegium Medicum 31-501 Krakow, 17 Kopernika St., Poland.
    The natural resources of iodine are seawater, seaweeds and saltpeter-nitrate deposits in Chile. Over 1/3 of the global population is exposed to iodine deficiency, especially in the mountains. Iodine is a component of the thyroid hormones and a strong antioxidant with electric potential of -0. Read More

    External validation of the GREAT score to predict relapse risk in Graves' disease: results from a multicenter, retrospective study with 741 patients.
    Eur J Endocrinol 2017 Apr 18;176(4):413-419. Epub 2017 Jan 18.
    Medical University DepartmentClinic for Endocrinology, Diabetes & Metabolism.
    Context: First-line treatment in Graves' disease is often done with antithyroid agents (ATD), but relapse rates remain high making definite treatment necessary. Predictors for relapse risk help guiding initial treatment decisions.

    Objective: We aimed to externally validate the prognostic accuracy of the recently proposed Graves' Recurrent Events After Therapy (GREAT) score to predict relapse risk in Graves' disease. Read More

    Monitoring the effects of iodine prophylaxis in the adult population of southern Italy with deficient and sufficient iodine intake levels: a cross-sectional, epidemiological study.
    Br J Nutr 2017 Jan 18;117(1):170-175. Epub 2017 Jan 18.
    1Department of Pharmacy, Health and Nutritional Sciences,University of Calabria,87036 Arcavacata di Rende (CS),Italy.
    I prophylaxis is the most effective strategy to eradicate I deficiency disorders, but it has been shown to affect the thyroid disease pattern. In this study, we assessed the frequency of thyroid disorders in an adult population living in two areas of southern Italy after implementing I prophylaxis. To this aim, a cross-sectional, population-based study including 489 subjects from an I-deficient rural and an I-sufficient urban area of southern Italy was conducted. Read More

    Metastasis of Renal Clear Cell Carcinoma to Thyroid Gland Mimicking Adenomatous Goiter.
    Pol J Radiol 2016 25;81:618-621. Epub 2016 Dec 25.
    Department of Radiology, Ataturk Training and Research Hospital, Izmir Katip Celebi University, Izmir, Turkey.
    Background: Renal cell carcinoma is an interesting tumor due to its unpredictable behavior. Common metastatic sites of renal cell carcinoma are the lungs, lymph nodes, bones and liver. Concurrent thyroid metastasis of clear cell carcinoma is uncommon but it can appear as a rapidly growing cervical, painless nodular mass. Read More

    Patient-tailored management of an asymptomatic massive substernal goiter presenting as brachiocephalic vein occlusion. Report of a case and review of sternotomy indications.
    Int J Surg Case Rep 2017 Jan 4;31:35-38. Epub 2017 Jan 4.
    1st Department of Surgery, 401 Army General Hospital of Athens, Greece.
    Introduction: Substernal goiters are characterized by the protrusion of at least 50% of the thyroid mass below the level of the thoracic inlet. Still their definition is controversial.

    Case Presentation: The case refers to a 44year old male who presented to our department due to swelling and a feeling of 'heaviness' of his left upper extremity for the past 6 months. Read More

    [The clinical definition and etiology of Pendred syndrome (a review of the literature and clinical observations)].
    Vestn Otorinolaringol 2016 ;81(6):25-31
    National Research Centre for Audiology and Hearing Rehabilitation, Russian Medico-Biological Agency, Moscow, Russia, 117513; Russian Medical Academy of Post-Graduate Education, Moscow, Russia, 125993.
    The aim of this work was a clinical study of the patients with mutations in the SLC26A4 gene and clinical diagnosis of the Pendred syndrome. The Pendred syndrome is a hereditary autosomal recessive disorder characterized by combined pathology of the inner ear and the thyroid gland. CT of the temporal bones demonstrates the Mondini-type structural anomaly in the inner ear and enlarged vestibular aqueduct. Read More

    [Surgical and combined correction of tracheal and laryngotracheal cicatricial stenosis and restenosis].
    Khirurgiia (Mosk) 2016 (12):31-36
    University's Clinical Hospital #4 of the Chair of Faculty Surgery #2, Medical Faculty of the Sechenov First Moscow State Medical University, Moscow, Russia.
    Aim: To improve treatment of patients with cicatricial tracheal stenosis using different methods of recanalization and circular resection.

    Material And Methods: Analysis involved 57 patients with cicatricial tracheal stenosis including 2 post-traumatic cases, 27 post-intubation cases, 25 cases after tracheostomy and 3 restenoses after previous circular resection. There were 5 cases of tracheal stenosis combined with tracheoesophageal fistula, 1 patient with chest nodular goiter, 8 cases of unclosed tracheostomy and 3 patients with long-existing laryngotracheal fissure. Read More

    A systematic review of combinatorial treatment with warming and invigorating drugs and levothyroxine for hypothyroidism caused by Hashimoto disease.
    Ann Transl Med 2016 Dec;4(23):459
    Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing 100091, China.
    Background: We used the systematic review method to evaluate the clinical efficacy and safety of combinatorial treatment with warming and invigorating drugs and levothyroxine on hypothyroidism caused by Hashimoto thyroiditis (HT).

    Methods: We set inclusion and exclusion criteria, searched for studies using electronic databases and manual retrieval, selected studies according to the inclusion and exclusion criteria, and assessed the qualities of the included studies according to the Jadad scale. We performed a meta-analysis and analyzed the biases and sensitivities of the results using Revman 5. Read More

    Expressions of miRNAs in papillary thyroid carcinoma and their associations with the clinical characteristics of PTC.
    Cancer Biomark 2017 ;18(1):87-94
    Endocrinology Department, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
    Background: The sensitivity and specificity of biomarkers which have been used in clinical practice for diagnosis of papillary thyroid carcinoma (PTC) are low, it is essential to develop novel diagnostic and prognostic biomarkers for PTC.

    Objective: To explore the expressions of miR-940, miR-15a, miR-16 and IL-23 in PTC tissues and plasma and their associations with the clinical characteristics of PTC.

    Methods: We investigated the expressions of miR-940, miR-15a, miR-16 and IL-23 in plasma and thyroid tissues of PTC, nodular goiter and healthy people with qRT-PCR, and further analyzed the associations between their levels and the clinical characteristics of PTC. Read More

    The way forward in Italy for iodine.
    Minerva Med 2017 Jan 12. Epub 2017 Jan 12.
    Endocrinology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
    Italy is dealing with iodine deficiency since ancient times. Indeed, iodine deficiency disorders, specifically goiter and cretinism, have been reported in some regions of Northern Italy already in the first century AD. However, a clear relationship between endemic goiter and endemic cretinism was recognized only in 1848 by an "ad hoc" committee appointed by the king of Sardinia, which identified extensive areas afflicted by these disorders in Piedmont, Liguria and Sardinia. Read More

    Fine needle aspiration cytology of 650 thyroid nodules operated for multinodular goiter: a cyto-histological correlation based on the new Italian cytological classification (siapec 2014).
    J Biol Regul Homeost Agents 2016 Oct-Dec;30(4):1187-1193
    Department of Surgical Sciences, “Sapienza” University of Rome, Rome, Italy.
    The new Italian cytological classification (SIAPEC 2014) of thyroid nodules, in line with those of Bethesda and BTA-RCPath, replaces the previous TIR3 class with two new classes (TIR3A and TIR3B), which correspond to different risks of malignancy and clinical actions required. The present study was conducted to evaluate the diagnostic accuracy of the new SIAPEC classification as opposed to its previous version (SIAPEC 2007). Preoperative cytology was compared with the final histology obtained from 650 consecutive patients who underwent total thyroidectomy for multinodular goiter. Read More

    Pattern of clinical benign euthyroid goitre in a tertiary care center in the Central Province of Sri Lanka from 1981-2011
    Ceylon Med J 2016 12;61(4):176-180
    Department of Surgery, Faculty of Medicine, University of Peradeniya, Sri Lanka.
    Objectives: To describe the pattern of clinical euthyroidgoitre in a tertiary care unit in Sri Lanka before and after iodination of salt in Sri Lanka.

    Methods: We reviewed our thirty-one year computerised database of patients with goitres, spanning iodination in 1995.

    Results: Prevalence of euthyroid clinical simple diffuse goitre did not reduce during the first thirteen years (p=0. Read More

    Differentiated thyroid cancer in Iran - initial observations, histological features, management of the disease, and tumor recurrence: A review of 1689 cases.
    Indian J Cancer 2016 Apr-Jun;53(2):261-264
    Students' Research Center, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
    Aim: The main objective of this study was to define some histopathological aspects of differentiated thyroid cancer (DTC), describe the disease management, and evaluate potential predicting factors for tumor recurrence in Iran.

    Materials And Methods: Medical records of 1689 patients of DTC treated over a 15-year period at a referral hospital located in the central region of Iran were reviewed retrospectively.

    Results: The female/male ratio was 3. Read More

    Poor dietary diversity, wealth status and use of un-iodized salt are associated with goiter among school children: a cross-sectional study in Ethiopia.
    BMC Public Health 2017 Jan 7;17(1):44. Epub 2017 Jan 7.
    Department of Human Nutrition, Institute of Public Health, College of Medicine and Health Sciences, University of Gondar, P.O. Box: 196, Gondar, Ethiopia.
    Background: Globally, more than two billion people are at risk of iodine deficiency disorders, 32% of which are school children. Iodine deficiency has been recognized as a severe public health concern in Ethiopia, however little is known about the problem. Therefore, this study aimed to assess the prevalence of goiter and associated factors among school children (6 to 12 years) in Dabat District, northwest Ethiopia. Read More

    Primary thyroid lymphoma: A case report and review of the literature.
    Ann Med Surg (Lond) 2017 Jan 21;13:29-33. Epub 2016 Dec 21.
    Endocrine Surgical Unit of Pedro Hispano Hospital, Matosinhos, Portugal; Faculdade de Medicina da Universidade do Porto, Alameda Professor Hernâni Monteiro, 4200-319, Porto, Portugal.
    Introduction: A rapidly enlarging mass of the anterior compartment of the neck with compressive symptoms may represent, among other diagnosis, a neoplasm of the thyroid gland.

    Presentation Of Case: We describe the case of a 59-year-old woman referred to the endocrine surgical unit because of compressive cervical symptoms for 3 months. The cervical ultrasound revealed a sub-sternal goiter with heterogeneous echo structure and the fine-needle aspirating cytology was inconclusive. Read More

    Bilateral brachiocephalic vein compression: an unusual and rare presentation of multinodular goitre.
    BMJ Case Rep 2016 Oct 8;2016. Epub 2016 Oct 8.
    Department of Radiology, Eastbourne District General Hospital, Eastbourne, UK.
    An interesting and rare case where a longstanding multinodular goitre causes sudden onset symptoms of superior vena cava obstruction. The symptoms were caused by bilateral brachiocephalic vein compression against the first rib. The patient's symptoms included upper limb and facial swelling, whereas her lower limbs were not oedematous (figure 1). Read More

    Clinicopathological Analysis of Mediastinal Masses: A Mixed Bag of Non-Neoplastic and Neoplastic Etiologies.
    Turk Patoloji Derg 2017 ;33(1):37-46
    1Department of Pathology, Vardhman Mahavir Medical College & Safdarjung Hospital, New DELHI, INDIA.
    Objective: The mediastinum is the central portion of the thoracic cavity, housing numerous organs and harbouring a mixed bag of non-neoplastic and neoplastic lesions. Accurate diagnosis is essential owing to the widely variable therapeutic and prognostic implications.

    Material And Method: Cases of mediastinal masses were retrospectively reviewed from January 2011 till January 2016. Read More

    A 33-Year-Old Man with Gynaecomastia and Galactorrhea as the First Symptoms of Graves Hyperthyroidism.
    Case Rep Endocrinol 2016 1;2016:1946824. Epub 2016 Dec 1.
    Division of Endocrinology and Metabolism, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
    Graves' hyperthyroidism has a various number of well-recognized manifestations. Galactorrhea is a rare manifestation in this disease. We describe a 33-year-old man who presented with the symptoms of hyperthyroidism, gynaecomastia, and galactorrhea for 2 months. Read More

    Content of RNA originating from thyroid in washouts from fine-needle and core-needle aspiration biopsy - preliminary study.
    Endokrynol Pol 2016 ;67(6):550-553
    Department of Endocrinology, Metabolism and Internal Medicine Poznan University of Medical Sciences.
    Introduction: In the evaluation of molecular markers in washouts from fine-needle aspiration biopsy (FNAB) the extremely small amount of material can be a major problem. Some authors tried to use washouts from core-needle aspiration biopsy (CNABs) to gain more material from larger needles. However, according to some studies, CNAB samples are commonly contaminated with blood. Read More

    Prophylactic oral calcium supplementation therapy to prevent early post thyroidectomy hypocalcemia and evaluation of postoperative parathyroid hormone levels to detect hypocalcemia: A prospective randomized study.
    Int J Surg 2017 Feb 27;38:9-14. Epub 2016 Dec 27.
    Baskent University Adana Teaching and Research Center, Department of General Surgery, Adana, Turkey. Electronic address:
    Background: Postoperative hypocalcemia is the most common complication after total thyroidectomy. Postoperative parathyroid hormone (PTH) measurement is one of the methods to detect or prevent postoperative hypocalcemia. Prophylactic oral calcium supplementation is another method to prevent early postoperative hypocalcemia. Read More

    Systematic review and meta-analysis on intra-operative neuro-monitoring in high-risk thyroidectomy.
    Int J Surg 2017 Feb 26;38:21-30. Epub 2016 Dec 26.
    Division of Endocrine Surgery, Department of Surgery, The University of Hong Kong, Queen Mary Hospital, Hong Kong Special Administrative Region.
    Introduction: Use of intra-operative neuro-monitoring (IONM) during high-risk thyroidectomy has been suggested to decrease the rate of recurrent laryngeal nerve (RLN) palsy. However, current evidences were mixed and there was no large-scale study concluding its benefit. We evaluated the role of IONM in reducing RLN palsy during high-risk thyroidectomy and identified which high-risk subgroup would be most benefited. Read More

    Infiltrative thyrotoxicosis: an unusual case of diffuse large B cell lymphoma.
    Oxf Med Case Reports 2016 Nov 4;2016(11):omw082. Epub 2016 Nov 4.
    Consultant Medical Oncologist, University Hospital Limerick , Limerick , Ireland.
    Thyrotoxicosis is most commonly caused by Graves' disease, toxic multinodular goitre, a functioning thyroid adenoma, or thyroiditis. Extrinsic infiltrative conditions affecting the thyroid gland are typically destructive, and associated with thyroid hypofunction. We describe the case of a 61-year-old woman who presented to our hospital with symptoms of thyrotoxicosis, neck swelling and thyroid function tests consistent with hyperthyroidism. Read More

    Takotsubo Cardiomyopathy Associated with Primary Hyperthyroidism Secondary to Toxic Multinodular Goiter.
    Int J Angiol 2016 Dec 23;25(5):e121-e122. Epub 2015 Mar 23.
    Department of Endocrinology, Gold Coast University Hospital, Gold Coast, Australia; School of Medicine, Griffith University, Gold Coast, Australia.
    Takotsubo cardiomyopathy is increasingly recognized as a distinct clinical entity. An association with thyroid disease has been identified in several case reports, mostly in the context of Grave disease. We report the case of a 67-year-old woman presenting with takotsubo cardiomyopathy and thyrotoxicosis secondary to toxic multinodular goiter. Read More

    Knowledge and Perception of Consumption of Iodized Salt Among Food Handlers in Southern Ethiopia.
    Food Nutr Bull 2016 Jan 1:379572116684909. Epub 2016 Jan 1.
    2 Wolaita Sodo University, WolaitaSodo, Ethiopia.
    Background: Iodine deficiency is the world's single most important cause of preventable mental retardation. In Ethiopia, the knowledge and perception of food handlers toward the iodized salt consumption (ISC) was very low.

    Objective: To assess knowledge and perception of food handlers toward consumption of iodized salt in Wolaita Sodo town and Sodo Zuria woreda, 2014. Read More

    Thyroid Surgery in a Resource-Limited Setting.
    Otolaryngol Head Neck Surg 2016 Dec 1:194599816684097. Epub 2016 Dec 1.
    6 Department of Surgery, Indiana University School of Medicine, Indianapolis, Indiana, USA.
    Objective The present study reviews a series of patients who underwent thyroid surgery in Eldoret, Kenya, to demonstrate the feasibility of conducting long-term (>1 year) outcomes research in a resource-limited setting, impact on the quality of life of the recipient population, and inform future humanitarian collaborations. Study Design Case series with chart review. Setting Tertiary public referral hospital in Eldoret, Kenya. Read More

    New Daily Persistent Headache Caused by a Multinodular Goiter and Headaches Associated With Thyroid Disease.
    Headache 2017 Feb 27;57(2):285-289. Epub 2016 Dec 27.
    Neuroradiology Private Practice.
    A 33-year-old female is presented with the first case to our knowledge of new daily persistent headache (NDPH) with a large right benign non-toxic multinodular goiter causing carotid and vertebral compression with complete resolution of the headache immediately after thyroidectomy. Although this may be quite rare, hypothyroidism or hyperthyroidism causing NDPH, migraine, or an exacerbation of pre-existing migraine is not. Clinicians should consider routinely obtaining serum thyroid-stimulating hormone (TSH) and free T4 in patients with new onset frequent headaches or an exacerbation of prior primary headaches. Read More

    Evaluation of Fetal Thyroid with 3D Gradient Echo T1-weighted MR Imaging.
    Magn Reson Med Sci 2016 Dec 26. Epub 2016 Dec 26.
    Division of Radiology, Department of Pathophysiological and Therapeutic Science, Faculty of Medicine, Tottori University.
    Purpose: The characteristics of fetal thyroid on magnetic resonance (MR) imaging, including normal thyroid and disorders other than goiter have not been fully evaluated. Our aim was to assess fetal thyroid using three dimensional (3D) gradient echo (GRE) T1-weighted MR imaging and to examine the usefulness of this modality.

    Materials And Methods: The study included 27 3D GRE T1-weighted images from 26 fetuses. Read More

    1 OF 727