Search Our Scientific Publications & Authors

Int J Pediatr Otorhinolaryngol 2021 Mar 29;145:110687. Epub 2021 Mar 29.

Department of Paediatric Otolaryngology, The Children's Hospital at Westmead, The University of Sydney, Westmead, NSW, Australia; Discipline of Child and Adolescent Health, Faculty of Medicine and Health, University of Sydney, NSW, Australia. Electronic address:

Objective: To report on our experience with open pediatric laryngotracheal reconstruction (LTR) with cartilage interposition grafts over the past 15 years and document setbacks and factors that affect postoperative outcomes.

Method: A retrospective chart review was performed on all pediatric patients who underwent single and double-stage LTR at The Children's Hospital in Westmead between August 2004 and July 2019. The outcomes measured include the overall decannulation rate, rates of postoperative complications, need for subsequent procedures and postoperative functional results (dyspnea, stridor, voice impairment). Read More

Otolaryngol Head Neck Surg 2021 Apr 13:1945998211004264. Epub 2021 Apr 13.

Department of Otolaryngology-Head and Neck Surgery, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.

Objective: Subglottic stenosis (SGS) is a known complication of granulomatosis with polyangiitis (GPA). We investigated the impact of medical and surgical interventions on the surgical dilation interval and characterized patients with glottic involvement.

Study Design: A retrospective chart review of patients with GPA-associated SGS was performed from 2010 to 2019. Read More

Burns 2021 Feb 27. Epub 2021 Feb 27.

US Army Institute of Surgical Research, Joint Base San Antonio, Fort Sam Houston, TX, USA. Electronic address:

Laryngeal inhalation injury carries a significant increase in mortality rate and often indicates immediate airway evaluation. This may be difficult in the setting of clinical deterioration necessitating immediate intubation, which itself can synergistically cause mucosal damage. Prior studies do not encompass predictive factors or long-term outcomes for the laryngotracheal complex. Read More

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2021 Mar;56(3):256-262

Department of Otorhinolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University,Beijing 100730,China.

To investigate the clinical characteristics, diagnosis, endoscopic surgical procedures, and therapeutic effect of blunt laryngeal trauma with arytenoid injury. We retrospectively reviewed 12 patients who suffered blunt laryngeal trauma with laryngeal mucosa avulsion and arytenoid region injury at the Department of Otorhinolaryngology Head and Neck Surgery, Beijing Tongren Hospital from April 2007 to December 2018. Among the 12 patients, 10 were males, 2 were females, aged from 7 to 48 years old, with a median age of 21 years old. Read More

Oral Oncol 2021 Feb 26;116:105230. Epub 2021 Feb 26.

Department of Radiation Oncology, Eye, Ear, Nose & Throat Hospital of Fudan University, Shanghai 200031, China. Electronic address:

Objectives: The study was intended to compare the outcomes for T1-T2N0M0 glottic squamous cell carcinoma with anterior commissure involvement who had undergone partial laryngectomy (PL) or radiotherapy (RT).

Materials And Methods: We retrospectively analyzed 256 patients who were treated by RT (n = 70) or PL (n = 186). Patients received prophylactic irradiation of the neck in RT group whereas PL was not associated with lymphadenectomy. Read More

Front Pediatr 2021 10;9:594832. Epub 2021 Feb 10.

Head and Neck Surgery Department, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.

Laryngeal intubation related lesions (LIRL) in pediatric patients cause extreme morbidity in both elective and emergency settings. It has a wide range of presentations from minor laryngeal edema to a life-threatening airway obstruction. We report here our units' experience with LIRL in neonates, infants, and small children. Read More

Ann Otol Rhinol Laryngol 2021 Mar 1:3489421997278. Epub 2021 Mar 1.

Division of Otolaryngology, Department of Surgery, Yale University School of Medicine, New Haven, CT, USA.

Objectives: To investigate surgical adjuncts (stents) and previous surgeries on outcomes from posterior glottic stenosis (PGS).

Methods: PubMED/Medline, CINAHL, EMBASE, and Web of Science were searched for publications on adult patients undergoing surgery for PGS. Decannulation and need for additional surgeries were evaluated as outcomes. Read More

BMJ Case Rep 2021 Feb 26;14(2). Epub 2021 Feb 26.

ENT/Otolaryngology, Royal Perth Hospital, Perth, Western Australia, Australia.

Glottic stenosis can be an unexpected finding during an intubation, causing difficulties that may result in a 'can't intubate, can't ventilate' situation. We present a case of a patient who required an emergency tracheostomy, in the setting of a failed intubation secondary to glottic stenosis. The patient underwent open laryngotracheal reconstruction, followed by tracheostomy decannulation 2 months post-surgery. Read More

Laryngoscope 2021 Feb 17. Epub 2021 Feb 17.

Department of Otolaryngology, Columbia University Medical Center, New York, New York, U.S.A.

Endoscopic posterior cricoid split and rib grafting (EPCS/RG) for the treatment of posterior laryngeal stenosis has some advantages over traditional open approaches, including improved surgical visualization and decreased morbidity. Many pediatric patients who undergo EPCS/RG have indwelling tracheostomy, which may be utilized to help manage the airway perioperatively. The role for de novo tracheostomy placement at the time of EPCS/RG is less clear. Read More

Postgrad Med 2021 Mar 2:1-4. Epub 2021 Mar 2.

Department of Anesthesiology, General Hospital of Ningxia Medical University, Yinchuan, Ningxia, China.

Severe postintubation tracheal stenosis (PITS) is a rare iatrogenic complication after endotracheal intubation. A case of PITS in a 51-year-old male undergoing partial pericardiectomy with a principal diagnosis of tuberculous constrictive pericarditis. Within 6 hours of extubation, a second emergency intubation lasting 120 hours was performed. Read More

Ann Otol Rhinol Laryngol 2021 Feb 15:3489421995285. Epub 2021 Feb 15.

Department of Otolaryngology, University of Maryland School of Medicine, Baltimore, MD, USA.

Objectives: To identify the incidence and risk factors for intubation-related laryngeal lesions that preclude tracheostomy decannulation in a large population.

Methods: A 3-year retrospective case-control study was performed of tracheotomized adults in acute rehabilitation facilities who underwent routine endoscopic evaluation of the airway as part of the facilities' decannulation protocol. Patients with known upper airway pathology, external laryngeal trauma, cricothyrotomy or emergent tracheostomy, prior head and neck radiation, isolated tracheal lesions, and patients with incomplete reports were excluded. Read More

Laryngoscope 2021 Feb 12. Epub 2021 Feb 12.

Department of Otolaryngology-Head and Neck Surgery, University of North Carolina, Chapel Hill, North Carolina, U.S.A.

Objectives/hypothesis: Glottic stenosis is a discrete cause of airway compromise. We aimed to determine the surgical outcomes of transverse cordotomy with anteromedial arytenoidectomy (TCAMA), performed in the setting of isolated glottic stenosis resulting from two discrete etiologies: bilateral vocal fold paralysis (BVFP) and posterior glottic stenosis (PGS).

Study Design: Retrospective, analytic cohort study. Read More

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2021 01;35(1):49-51

Department of Otorhinolaryngology Head and Neck Surgery，First Affiliated Hospital of Anhui Medical University，Hefei，230022，China.

To explore the value of endoscopic-assisted modified cricothyroid membrane approach laryngeal surgery in patients with difficult airways and evaluate its safety. All patients with laryngeal surgery who were hospitalized were evaluated. For the patients with difficult airways those could not be exposed through routine surgical approach, after full communication, we carried out the endoscope-assisted modified loop thyroscopic approach to the thyroid membrane. Read More

JAMA Otolaryngol Head Neck Surg 2021 03;147(3):232-237

Department of Otolaryngology-Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, Tennessee.

Importance: Patients with laryngeal injury after endotracheal intubation often present long after initial injury with mature fibrosis compromising cricoarytenoid joint mobility and glottic function.

Objective: To compare functional outcomes between early and late intervention for intubation-related laryngeal injury.

Design, Setting, And Participants: This retrospective cohort study involved 29 patients with laryngeal injury resulting from endotracheal intubation who were evaluated at a tertiary care center between May 1, 2014, and June 1, 2018. Read More

Am J Case Rep 2021 Jan 18;22:e928743. Epub 2021 Jan 18.

Department of Anesthesiology and Critical Care Medicine, Kyushu University Graduate School of Medicine, Fukuoka City, Fukuoka, Japan.

BACKGROUND Tracheobronchopathia osteochondroplastica (TO) is a rare disorder characterized by cartilaginous or ossified submucosal nodules of unknown etiology that project into the tracheobronchial lumen. TO is often accompanied by endotracheal stenosis from cartilage proliferation and is often detected by difficult endotracheal intubation incidence. CASE REPORT Here we report the case of a patient (67-year-old man) with TO scheduled to undergo robot-assisted total prostatectomy for prostate cancer. Read More

J Thorac Cardiovasc Surg 2021 Mar 14;161(3):845-852. Epub 2020 Dec 14.

Division of Thoracic Surgery, Sant'Andrea Hospital, Sapienza University of Rome, Rome, Italy.

Objective: Laryngotracheal resection is still considered a challenging operation and few high-volume institutions have reported large series of patients in this setting. During the 5 years, novel surgical techniques as well as new trends in the intra- and postoperative management have been proposed. We present results of our increased experience with laryngotracheal resection for benign stenosis. Read More

Laryngoscope Investig Otolaryngol 2020 Dec 30;5(6):1117-1124. Epub 2020 Oct 30.

Department of Otolaryngology-Head and Neck Surgery Massachusetts Eye and Ear Infirmary Boston Massachusetts USA.

Objective: To describe and visually depict laryngeal complications in patients recovering from coronavirus disease 2019 (COVID-19) infection along with associated patient characteristics.

Study Design: Prospective patient series.

Setting: Tertiary laryngology care centers. Read More

J Voice 2020 Dec 23. Epub 2020 Dec 23.

Department of Otolaryngology - Head and Neck Surgery, Drexel University College of Medicine, and Lankenau Institute for Medical Research, Philadelphia, Pennsylvania. Electronic address:

Objectives: To introduce a novel surgical technique for the management of posterior glottic stenosis (PGS).

Methods: Literature review (PubMed 1973-2020) and case example of a patient treated with novel technique by principal investigator (R.T. Read More

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2020 Dec;55(12):1131-1136

Otorhinolaryngology Hospital, First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, China.

To investigate the clinical efficacy of acellular dermis matrix combined with cervical strap muscle (ADM-CSM) as a composite tissue flap for repairing the laryngeal defect after partial laryngectomy. The medical records of 33 patients with laryngeal cancer who were diagnosed and treated at the First Affiliated Hospital of Sun Yat-sen University from January 2014 to December 2016 were retrospectively reviewed. The patients consisted of 32 males and 1 female with age range from 39 to 76 years. Read More

BMJ Case Rep 2020 Dec 17;13(12). Epub 2020 Dec 17.

Department of ENT & Head and Neck Surgery, All India Institute of Medical Sciences, New Delhi, Delhi, India.

A 29-year-old male patient presented with a history of voice change and feeling of a lump in throat for the last 20 years. He was tracheostomised at the age of 10 years. Endolaryngeal examination showed a mucosal bulge in supraglottic region arising predominantly from right side. Read More

Otolaryngol Head Neck Surg 2020 Dec 8:194599820978276. Epub 2020 Dec 8.

Department of Otorhinolaryngology-Head and Neck Surgery, University of Maryland School of Medicine, Baltimore, Maryland, USA.

Objective: Predictors of tracheostomy decannulation in patients with laryngotracheal stenosis are not fully known, making prognosis difficult. The aim was to identify predictors of tracheostomy decannulation in adult patients with acquired stenosis of the larynx and/or trachea who were tracheostomy dependent.

Study Design: Case series. Read More

Laryngoscope 2021 04 14;131(4):E1220-E1226. Epub 2020 Oct 14.

Center for Pulmonary Imaging Research, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, U.S.A.

Objectives: Subglottic stenosis (SGS) is the most common type of laryngeal stenosis in neonates. SGS severity is currently graded based on percent area of obstruction (%AO) via the Myer-Cotton grading scale. However, patients with similar %AO can have widely different clinical courses. Read More

Laryngoscope 2021 05 2;131(5):E1633-E1637. Epub 2020 Dec 2.

UCSF Voice and Swallowing Center, Division of Laryngology, Department of Otolaryngology - Head and Neck Surgery, University of California, San Francisco, California, U.S.A.

J Thorac Dis 2020 Oct;12(10):6152-6162

Lung Clinic, Hospital of Cologne, Chair of Thoracic Surgery, Private University of Witten/Herdecke, Köln, Germany.

Cervical stenosis of the trachea caused by tracheotomy, tumor or induced by inflammatory disease can be treated by resection and anastomosis with good early and long-term results. Involvement of the ring cartilage makes the procedure technical demanding and increases the risk of morbidity. We describe our technique of laryngotracheal resection and reconstruction and compare the perioperative results with standard trachea resection. Read More

Front Pediatr 2020 19;8:555040. Epub 2020 Oct 19.

Division of Pediatric Otolaryngology, Aerodigestive and Esophageal Center, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States.

Congenital webs are rare and represent <5% of all congenital laryngeal anomalies. They are usually a partial laryngeal atresia rather than a true web, and present as a thick and fibrotic web with subglottic extension and associated subglottic stenosis. All patients with a congenital anterior glottic web should be evaluated for chromosome 22q11. Read More

Int J Pediatr Otorhinolaryngol 2020 Dec 28;139:110474. Epub 2020 Oct 28.

Naval Medical Center San Diego Department of Otolaryngology-Head and Neck Surgery, San Diego, CA, USA. Electronic address:

Introduction: Several animal models of subglottic stenosis (SGS) have been described in the literature, however many result in severe stenosis that requires early intervention and carry a high mortality rate. This limits the application of the model and may require the use of additional animals to achieve desired results due to procedural complications. A novel endoscopic method of inducing SGS in a rabbit model was developed as part of a larger investigation on the treatment of this condition. Read More

Thorax 2021 01 29;76(1):44-52. Epub 2020 Oct 29.

Department of Pediatric Othorhinolaryngology, Erasmus MC Sophia, Rotterdam, The Netherlands.

Rationale: Paediatric laryngotracheal stenosis (LTS) is often successfully corrected with open airway surgery. However, respiratory and vocal sequelae frequently remain. Clinical care and surgical interventions could be improved with better understanding of these sequelae. Read More

Intern Emerg Med 2020 Oct 23. Epub 2020 Oct 23.

Department of Respiratory Medicine, Beijing Tian Tan Hospital, Capital Medical University, No. 119, South Fourth Ring West Road, Fengtai District, Beijing, 100070, China.

The purpose of this study is to report our experiences over 12 years with bronchoscopic interventions in patients with benign central airway stenosis using three types of working channels (rigid bronchoscope, laryngeal mask, and endotracheal intubation), with a focus on their related advantages, disadvantages, and postoperative complications. We analyzed the clinical data from 273 patients with benign central airway stenosis who underwent a bronchoscopic intervention. The Wilcoxon rank-sum test was used to analyze the immediate results after the first bronchoscopic intervention, and the Chi-square test was used to analyze the correlation between glottic edema and operation time. Read More

Int J Pediatr Otorhinolaryngol 2020 Dec 13;139:110409. Epub 2020 Oct 13.

University of Central Florida College of Medicine, University of Central Florida, Orlando, FL, USA; Department of Pediatric Otolaryngology, Nemours Children's Hospital, Orlando, FL, USA. Electronic address:

Laryngotracheobronchitis is a common, typically self-limiting viral infection. However, severe laryngotracheobronchitis can require urgent intubation to prevent imminent airway obstruction. The concurrent inflammation and urgency make laryngeal trauma more likely. Read More

Curr Opin Otolaryngol Head Neck Surg 2020 Dec;28(6):414-424

Department of Pediatric Otolaryngology - Head and Neck Surgery, Arkansas Children's Hospital, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.

Purpose Of Review: Pediatric posterior glottic stenosis (PGS) is a challenging clinical entity with multiple treatment options. This review describes the evaluation of patients with PGS and discusses existing surgical techniques.

Recent Findings: PGS secondary to a distinct scar band between the vocal folds can often be effectively managed with endoscopic division and surveillance. Read More