16,688 results match your criteria Glottic Stenosis


Molecular and immunologic analysis of laryngeal squamous cell carcinoma in smokers and non-smokers.

Am J Otolaryngol 2018 Nov 22. Epub 2018 Nov 22.

Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins Hospital, Baltimore, MD, USA.

Background: Laryngeal squamous cell carcinoma (LSCC) is strongly associated with tobacco use, but recent reports suggest an increasing incidence of LSCC in patients without traditional risk factors, suggesting an alternative etiology of tumorigenesis. The purpose of this study is to characterize this non-smoking population and to compare immunohistochemical markers in tumor specimens from non-smokers and smokers with LSCC.

Methods: A retrospective chart review of patients with LSCC at Johns Hopkins Hospital (JHH) was performed. Read More

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November 2018

[Endoscopic keel placementto treat and prevent-bilateral vocal cord adhension].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Dec;32(23):1821-1825

Department of Otorhinolaryngology Head and Neck Surgery, Eye Ear Nose Throat Hospital of Fudan University, Shanghai, 200031, China.

To investigate the effectiveness of endoscopic keel placement for the prevention and treatment of bilateral vocal cord adhesion. There are 47 cases with bilateral vocal cord lesions and 38 cases with laryngeal adhesion in this study. Bilateral vocal cord lesions were removed and laryngeal adhesion was cut and divided. Read More

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December 2018
1 Read

[Analysis of infants with moderate to severe laryngomalacia].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Sep;32(18):1406-1409

Department of Otolaryngology Head and Neck Surgery, the First Affiliated Hospital of Xiamen University, Xiamen, 361003, China.

To investigate the clinical features and the treatment of moderate-severe laryngeallacia, and the application of CO₂laser supraglotation in laryngeallacia.Collecting the clinical data of 18 infants with moderate-to-severe laryngeallacia diagnosed in our hospital,10 cases were moderate. Eight cases were severe children; according to the classification of laryngeallacia, most of them were mixed type, including 2 cases of type Ⅱ, 3 cases of type Ⅲ, 5 cases of typeⅠ + type Ⅱ, 7 cases of typeⅡ+ type Ⅲ, and 1 case of typeⅠ+ typeⅡ + type Ⅲ. Read More

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September 2018

Isolated Recovery of Adductor Muscle Function Following Bilateral Recurrent Laryngeal Nerve Injuries.

Laryngoscope 2018 Dec 13. Epub 2018 Dec 13.

Department of Otorhinolaryngology-Head and Neck Surgery, University of Szeged, Szeged, Hungary.

Objectives/hypothesis: The aim of this study was to analyze the phoniatric and respiratory outcomes of a subset of bilateral vocal cord paralysis (BVCP) patients who were all treated with unilateral endoscopic arytenoid abduction lateropexy (EAAL). EAAL is a nondestructive, minimally invasive glottis widening operation, which does not damage either the surgically treated or the contralateral vocal cord. Therefore, it does not impair the regeneration potential of the recurrent laryngeal nerve. Read More

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December 2018

Long-term changes in vocal function after supracricoid partial laryngectomy with cricohyoidoepiglottopexy for laryngeal cancer.

Head Neck 2018 Dec 12. Epub 2018 Dec 12.

Department of Otolaryngology-Head and Neck Surgery, Graduate School of Medicine, Kumamoto University, Kumamoto, Japan.

Background: The purpose of this study was to assess changes in vocal function over time following supracricoid partial laryngectomy with cricohyoidoepiglottopexy (SCL-CHEP).

Methods: A total of 17 patients who underwent SCL-CHEP for laryngeal squamous cell carcinoma between 2007 and 2015 were reviewed. We examined maximum phonation time (MPT), mean airflow rate (MFR), voice intensity, the grade, roughness, breathiness, asthenia, and strain (GRBAS) scale, Voice Handicap Index-10 (VHI-10), and voice-related quality of life (V-RQOL) scores. Read More

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December 2018

Phonosurgical Resection Using Submucosal Infusion Technique for Early Glottic Lesions: Diagnostic and Therapeutic Procedure?

Ann Otol Rhinol Laryngol 2018 Dec 14:3489418819544. Epub 2018 Dec 14.

1 Clinic of Otolaryngology, Head and Neck Surgery, Department of Translational Surgery and Medicine, Careggi University Hospital, Florence, Italy.

Objectives:: The aim of this study was to assess the feasibility of the submucosal infusion combined with microflap dissection via laser CO2 as both a diagnostic and therapeutic procedure for superficial glottic lesions. To define a safe surgical procedure in terms of local control, a morphometric study of surgical margins was performed.

Methods:: From January 2011 to January 2016, we treated 122 patients with early glottic lesions with phonomicrosurgery. Read More

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December 2018

[Feasibility of supraglottic tracheal tube ventilation during painless fiberbronchoscopy].

Zhonghua Yi Xue Za Zhi 2018 Dec;98(46):3767-3772

Department of Anesthesiology, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou 310006, China.

To evaluate the feasibility and safety of supraglottic tracheal tube ventilation by comparing with modified laryngeal mask airway ventilation during painless fiberbronchoscopy. This was a prospective study. Twenty-eight patients undergoing painless fiberbronchoscopy in Hangzhou First People's Hospital were randomly divided into 2 groups(=14): supraglottic tracheal tube ventilation(group A) and modified laryngeal mask airway(group B). Read More

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December 2018

Efficacy of laser surgery versus radiotherapy for treatment of glottic carcinoma: a systematic review and meta-analysis.

Lasers Med Sci 2018 Dec 6. Epub 2018 Dec 6.

Nursing College of Shanxi Medical University, Taiyuan, 030001, Shanxi, People's Republic of China.

Laser surgery and radiotherapy are the two most common ways to treat glottic carcinomas, which is more efficacious and remains controversial. PubMed, Embase, and Cochrane Library were searched to identify relevant studies of laser surgery versus radiotherapy in patients with glottic carcinomas through April 2017. Sensitivity analysis and subgroup analysis were performed to evaluate heterogeneity. Read More

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December 2018

Importance of glottis landmarks for the assessment of cleft lip and palate speech intelligibility.

J Acoust Soc Am 2018 Nov;144(5):2656

Department of Electronics and Electrical Engineering, Indian Institute of Technology Guwahati, Guwahati, Assam 781039, India.

The present work explores the acoustic characteristics of articulatory deviations near g(lottis) landmarks to derive the correlates of cleft lip and palate speech intelligibility. The speech region around the g landmark is used to compute two different acoustic features, namely, two-dimensional discrete cosine transform based joint spectro-temporal features, and Mel-frequency cepstral coefficients. Sentence-specific acoustic models are built using these features extracted from the normal speakers' group. Read More

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November 2018

Completion Total Laryngectomy Ten Years After Near Total Laryngectomy for Radiorecurrent Cancer of the Glottis.

Indian J Surg Oncol 2018 Dec 9;9(4):605-608. Epub 2018 Aug 9.

Division of Surgical Oncology (Head and Neck Services), Regional Cancer Centre, Trivandrum, Kerala 695011 India.

Near total laryngectomy (NTL) is a safe alternative to total laryngectomy in salvaging lateralized radiation failures. A 65-year-old gentleman with radiorecurrent T1 vocal cord cancer was salvaged successfully by NTL. Ten years later, he presented with a strained shunt speech which was treated judiciously, with the aid of a positron emission tomography (PET) scan, by a (completion) total laryngectomy (TL), bilateral selective neck dissection, and pharyngeal resurfacing with pectoralis major myocutaneous (PMMC) flap. Read More

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December 2018

Sclerosis of the arytenoid cartilage and glottic carcinoma: A clinical-pathological study.

Head Neck 2018 Dec 7. Epub 2018 Dec 7.

Otolaryngology Unit, Vittorio Veneto Hospital, Treviso, Italy.

Background: Given the relevance of any tumor invasion of the arytenoid cartilage or crico-arytenoid unit to the planning open partial horizontal laryngectomy (OPHL) for laryngeal squamous cell carcinoma (LSCC), it is important to have a reliable radiological test to assess impairments of these structures.

Methods: We retrospectively compared the endoscopic, radiological, and pathological findings in patients with glottic LSCC who underwent OPHL.

Results: The endoscopic finding of a reduced (impaired or absent) vocal cord motility proved more sensitive, with better positive and negative predictive values, but less specific than the radiological finding of complete arytenoid sclerosis in detecting histologically assessable infiltration of the arytenoid cartilage. Read More

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December 2018
1 Read

Epiglottopexy by external puncture for epiglottic prolapse in severe laryngomalacia. A novel technique.

Eur Ann Otorhinolaryngol Head Neck Dis 2018 Dec 4. Epub 2018 Dec 4.

Department of pediatric thoracic surgery, Hospital Infantil de México, Federico Gómez, Mexico.

Introduction: Laryngomalacia (LM) is the first cause of stridor in infants. 10 to 20% of patients with LM may require surgery due to the development of severe symptoms. Supraglottoplasty is the most commonly performed surgery for severe LM. Read More

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December 2018

Treatment of early-stage laryngeal cancer: A comparison of treatment options.

Oral Oncol 2018 Dec 16;87:8-16. Epub 2018 Oct 16.

Stanford University School of Medicine, Department of Otolaryngology Head and Neck Surgery, USA.

Over the course of the last several decades, the treatment options for early laryngeal cancers (T1 and T2) have evolved; however, simultaneously the mortality rate has increased. As larynx preservation approaches have become the standard of care, the selection of the proper treatment modality has become paramount. Radiation therapy or transoral laser microsurgery are the most common options for treatment of these early lesions. Read More

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December 2018
1 Read

Multi-institutional Evaluation of Medialization Laryngoplasty in the Elderly.

Otolaryngol Head Neck Surg 2018 Dec 11:194599818817762. Epub 2018 Dec 11.

3 Department of Otolaryngology-Head and Neck Surgery, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.

Objective: To evaluate voice outcomes of medialization laryngoplasty in the elderly population (65 years and older) and to identify swallow outcomes, complication rates, and predictors of voice outcomes.

Study Design: Case series with chart review.

Setting: Two tertiary academic medical centers. Read More

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December 2018
2 Reads

Outcomes of Treating Early Glottic Neoplasms With a Potassium Titanyl Phosphate Laser.

Ann Otol Rhinol Laryngol 2018 Dec 11:3489418806914. Epub 2018 Dec 11.

2 Auckland City Hospital, Auckland, New Zealand.

Objectives:: The aim of this study was to assess the outcome of treating glottic dysplasia and early squamous cell carcinoma (SCC) with potassium titanyl phosphate (KTP) photoangiolytic laser ablation.

Methods:: Patient demographics, comorbidities, and tumor characteristics were recorded. Perceptual, patient-reported, and objective voice outcomes were assessed. Read More

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December 2018
2 Reads

Carbon Dioxide Laser Microsurgery versus Low-Temperature Plasma Radiofrequency Ablation for T1a Glottic Cancer: A Single-Blind Randomized Clinical Trial.

Biomed Res Int 2018 1;2018:4295960. Epub 2018 Nov 1.

Department of Otolaryngology, The Third Hospital of Wuhan City, Wuhan, Hubei Province, China.

Background: Very few studies have been conducted to compare carbon dioxide laser microsurgery (CO2-LS) with low-temperature plasma radiofrequency ablation (LTP-RFA) in treating T1a glottic cancer. Therefore, we conducted this study to compare the efficacy of CO2-LS and LTP-RFA to define a superior therapeutic modality for T1a glottic cancer.

Methods: Patients (n=131) with T1a glottic cancer were recruited between January 2010 and September 2014. Read More

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November 2018
1 Read

Impact of the anterior commissure involvement on the survival of early glottic cancer treated with cricohyoidoepiglottopexy: a retrospective study.

Cancer Manag Res 2018 8;10:5553-5558. Epub 2018 Nov 8.

Otolaryngology, Department of Health Sciences, University of Catanzaro, Catanzaro, Italy,

Background: Laryngeal early glottic tumors can benefit from different treatment modalities, including transoral laser microsurgery, open partial horizontal laryngectomy (OPHL), and radiotherapy. However, the treatment of early glottic tumors with the involvement of the anterior commissure remains controversial. The studies about the role of anterior commissure involvement in oncologic outcomes in patients with early glottic cancer treated with supracricoid laryngectomy (SCL) are very few. Read More

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November 2018
1 Read

A Lodged Barramundi Fish-Bone Stabbing the Piriform Fossa in a Child.

Pediatr Emerg Care 2018 Dec;34(12):e243-e245

Pediatric Otolaryngology-Head & Neck Surgery, BC Children's Hospital, Vancouver, British Columbia, Canada.

Unintentional ingestion of a fish bone is common in children, especially among families with high consumption of seafood. Complications in children are extremely rare. We describe a 3-year-old healthy boy who had a large bone of Barramundi fish lodged in his upper esophagus causing significant distress. Read More

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December 2018
1 Read

Haemodynamic Response to Four Different Laryngoscopes.

Turk J Anaesthesiol Reanim 2018 Dec 6;46(6):434-440. Epub 2018 Sep 6.

Department of Anaesthesiology and Reanimation, İstanbul University İstanbul School of Medicine, İstanbul, Turkey.

Objective: In this prospective randomized study, we aimed to evaluate the effect of tracheal intubation with four different laryngoscopes [Macintosh direct laryngoscope-classic laryngoscope (CL), McCoy (MC), C-Mac video-laryngoscope (CM) and McGrath video-laryngoscope (MG)] on haemodynamic responses in patients with a normal airway.

Methods: One hundred and sixty patients were included. Succeeding haemodynamic measurements were performed immediately after intubation (T2) and for 5 min with 1-min intervals (T3-T4-T5-T6-T7). Read More

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December 2018
1 Read

Treatment of Patients with Vocal Fold Atrophy and Comorbid Essential Voice Tremor: Long-Term Injection Augmentation Outcomes After Successful Diagnostic Vocal Fold Injection Augmentation.

J Voice 2018 Nov 29. Epub 2018 Nov 29.

Division of Otolaryngology, Department of Surgery, Brigham and Women's Hospital, Boston, Massachusetts. Electronic address:

Objective: Vocal fold injection augmentation (VFIA) is employed diagnostically for patients with subtle glottic insufficiency. Its use in patients with both vocal fold atrophy and benign essential voice tremor (EVT) has been reported but not after durable augmentation. This study intends to evaluate the success of durable VFIA using either autologous fat or calcium hydroxylapatite in patients with both vocal fold atrophy and comorbid EVT. Read More

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November 2018

Use of bovine pericardium for the treatment of anterior iatrogenic glottic web.

Laryngoscope 2018 Dec 4. Epub 2018 Dec 4.

Ear, Nose, and Throat Department, Valencia University General Hospital and Valencia Medical School, Valencia, Spain.

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December 2018
2 Reads

Omitting the lower neck and sparing the glottic larynx in node-negative nasopharyngeal carcinoma was safe and feasible, and improved patient-reported voice outcomes.

Clin Transl Oncol 2018 Dec 4. Epub 2018 Dec 4.

Department of Oral and Maxillofacial-Head Neck Oncology, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, 639 Zhizaoju Road, Shanghai, 200011, People's Republic of China.

Background: Worsening voice and speech quality was frequently reported in head-and-neck patients after radiotherapy to the neck; omitting the lower neck and sparing the glottic larynx in node-negative nasopharyngeal carcinoma (NPC) patients might be safe and feasible, and improve voice and speech outcomes.

Methods: From January 2009 to January 2013, 71 patients were analyzed. All patients received bilateral neck irradiation. Read More

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December 2018
4 Reads

Recurrent oedema of the uvula in a patient with chronic spontaneous urticaria successfully treated with omalizumab.

Authors:
A Pannofino

J Dermatolog Treat 2018 Dec 4:1-4. Epub 2018 Dec 4.

a Allergology and Immunology Clinic , Operative Unit of Medicine , Policoro Hospital, Matera , Italy .

Uvula oedema is a condition characterized by a sensation of a foreign body in the oropharynx and difficulty to speak; sometimes, if associated to glottis oedema, difficulty to breathe and dysphonia are also present. Urticaria is a disease characterized by itching wheals on the skin, and sometimes angioedema. Chronic urticaria is spontaneous when the aetiology is unknown. Read More

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December 2018
3 Reads

Comparative evaluation of CMAC and Truview picture capture device for endotracheal intubation in neonates and infants undergoing elective surgeries: A prospective randomized control trial.

Paediatr Anaesth 2018 Dec;28(12):1148-1153

Scientist (Statistician), DRBRAIRCH, AIIMS, New Delhi, India.

Background: Videolaryngoscopy has an established role in difficult airway management in adults. However, there is limited literature to support their efficacy in children. The Truview Picture Capture Device has shown promising results for endotracheal intubation in infants in the past. Read More

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December 2018
3 Reads

Airtraq DL and AWS-200 for Double-lumen Endotracheal Tube Intubation: A Prospective Randomized Clinical Trial.

Tokai J Exp Clin Med 2018 Dec 20;43(4):161-167. Epub 2018 Dec 20.

Department of Anesthesiology, Hachioji-hospital, Tokai University School of Medicine, 1838 Ishikawamachi, Hachioji, Tokyo 192-0032, Japan:

Objective: This prospective randomized study aimed to assess the usefulness of two videolaryngoscopes with a side channel, the Airtraq DL and the AWS-200, for intubation with a double-lumen tube (DLT).

Methods: In 60 patients with an American Society of Anesthesiologists physical status of 1-3 who were not expected to have difficult airway, the Airtraq DL and the AWS-200 were randomly used for DLT intubation. The primary outcome was intubation time. Read More

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December 2018

Glottic configuration changes and outcomes of endoscopic arytenoid abduction lateropexy.

Eur Arch Otorhinolaryngol 2018 Nov 27. Epub 2018 Nov 27.

Department of Otorhinolaryngology-Head and Neck Surgery, University of Szeged, 111. Tisza L. krt, Szeged, 6725, Hungary.

Introduction: Endoscopic arytenoid abduction lateropexy (EAAL) is an effective glottis enlarging procedure for the treatment of bilateral vocal cord palsy (BVCP). The postoperative glottic configuration changes can be evaluated by modern, high-resolution, 3D image reconstructions. Functional results are described by spirometry as well as objective and subjective phoniatric tests. Read More

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November 2018
3 Reads

A comparison of the Macintosh laryngoscope, McGrath video laryngoscope, and Pentax Airway Scope in paediatric nasotracheal intubation.

Sci Rep 2018 Nov 26;8(1):17365. Epub 2018 Nov 26.

Department of Anesthesiology and Pain Medicine, Ajou University School of Medicine, Suwon, Republic of Korea.

We evaluated the performance of the McGrath video laryngoscope and Pentax Airway Scope in comparison with the Macintosh laryngoscope for nasotracheal intubation in paediatric patients. For this, 108 patients were enrolled in an open-label, randomized controlled trial. Patients were randomly allocated to one of three groups based on use of the Macintosh laryngoscope, McGrath video laryngoscope, or Pentax Airway Scope. Read More

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November 2018
4 Reads

Fundamental Frequency in Excised Human Larynges after Anterior Glottic Web Formation of Various Extents.

Otolaryngol Head Neck Surg 2018 Nov 27:194599818813007. Epub 2018 Nov 27.

1 Department of Otorhinolaryngology, School of Medicine, Universidade de São Paulo, São Paulo, Brazil.

Objective: To determine the effect of vocal fold anterior web formation on fundamental frequency with a cadaveric excised larynx model.

Study Design: Experimental study with excised human larynges.

Setting: Academic tertiary care hospital. Read More

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November 2018
1 Read

Mucosal bridges (MB): a 9-year retrospective study of their incidence with a third variant proposed.

Eur Arch Otorhinolaryngol 2018 Nov 26. Epub 2018 Nov 26.

Bombay Hospital and Medical Research Center, Mumbai, India.

Background: Mucosal bridges (MBs) are rare laryngeal lesions that may cause dysphonia of varying degrees. We propose the existence of a third variant of MB besides thin and thick MBs, and have termed this as an incomplete mucosal bridge (IMB). The concept of an IMB has not been previously discussed in literature. Read More

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November 2018
1.608 Impact Factor

Isolated Paresis of Laryngeal Adduction: What Are the Laryngoscopic and Stroboscopic Findings?

Laryngoscope 2018 Nov 25. Epub 2018 Nov 25.

Department of Otorhinolaryngology, School of Medicine, University of Sao Paulo, Sao Paulo, Brazil.

Objectives/hypothesis: This study aimed to describe the videolaryngostroboscopic (VLS) findings in a cohort of patients with isolated paresis of laryngeal adduction and identify predictive variables that may be related to voice recovery.

Study Design: Chart review and VLS analysis of dysphonic patients diagnosed with isolated paresis of laryngeal adduction by laryngeal electromyography (LEMG).

Methods: Demographic, clinical, VLS, and LEMG findings were analyzed according to the outcome of dysphonia. Read More

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November 2018
4 Reads

Fibreoptic-guided tracheal intubation through i-gel and LMA Protector supraglottic airway devices - a randomised comparison.

Anaesthesia 2018 Nov 22. Epub 2018 Nov 22.

Nuffield Department of Anaesthetics, Oxford University Hospitals NHS Foundation Trust.

Fibreoptic-guided tracheal intubation using a supraglottic airway device as a conduit is a technique that can be used in anticipated and unanticipated difficult airway management. Although the i-gel supraglottic airway device has been examined for this purpose, the LMA Protector , a recently introduced second-generation supraglottic airway device, has not been evaluated for this use in clinical trials. This prospective, randomised clinical trial compared fibreoptic-guided tracheal intubation via i-gel and LMA Protector supraglottic airway devices in two UK hospitals. Read More

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November 2018

"Hanger" in Intubation and Laryngoscopy.

Indian J Otolaryngol Head Neck Surg 2018 Dec 3;70(4):591-596. Epub 2018 Apr 3.

Grant Medical College and Sir JJ Group of Hospitals, Room No 216, 300 Resident Hostel, Byculla, Mumbai, Maharashtra 400008 India.

Achieving an adequate exposure in laryngoscopy is an extremely tedious task for the operating surgeon, especially for the anterior commissure lesions. Various maneuvers have been described to overcome this difficulty, but failed in providing an adequate exposure leading to a poor outcome. To create a device that can deliver uniform pressure over the laryngeal cartilage and succeed in providing an adequate exposure of the glottic lesion. Read More

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December 2018
2 Reads

Long Term Oncological Results of Transoral Laser Microsurgery for Early and Moderately Advanced Glottic Carcinoma in Primary and Salvage Settings.

Indian J Otolaryngol Head Neck Surg 2018 Dec 29;70(4):463-470. Epub 2018 Sep 29.

1Department of Otolaryngology and Head & Neck Surgery, All India Institute of Medical Sciences, New Delhi, 110029 India.

The aim of the study is to document the long term oncological results of trans-oral laser microsurgery (TLM) for early and moderately advanced glottic cancer in primary and salvage settings. In this prospective cohort study 43 consecutive patients of glottic cancer (T1-30, T2-7, and selected T3 with mobile cords-6) were recruited. TLM was performed in these 35 primary and 8 previously treated cases. Read More

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December 2018
1 Read

[Impact of Respiratory Motion on Dose Variation in Radiation Therapy for Glottic Cancer].

Nihon Hoshasen Gijutsu Gakkai Zasshi 2018 ;74(11):1269-1274

Department of Radiation Therapy, Cancer Institute Hospital.

In radiation therapy for glottic cancer, respiratory motion of larynx may change the dose variation in the target. The purpose of this study is to measure the respiratory motion of the larynx, and quantify the impact of the motion on the dose variation. This study included 10 patients treated by opposing portal irradiation for glottic cancer. Read More

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January 2018
1 Read

Narrow band imaging in transoral laser microsurgery (TLM) in moderately advanced (T2, T3) glottic cancer.

Otolaryngol Pol 2018 Aug;72(5):17-23

Department of Otolaryngology, Head and Neck Surgery, Poznań University of Medical Sciences, Poznań, Poland.

Introduction: Treatment planning in T2, T3 laryngeal carcinoma is based on clinical assessment and radiological imaging. However, to delineate precise mucosal margins for transoral laser microsurgery (TLM), a high class, sophisticated endoscopy is indispensable. Narrowband imaging (NBI) which is an optical filter technology, seems to be a useful adjunctive tool in marking superficial margins. Read More

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August 2018
7 Reads

Immunohistochemical analysis of vocal cord polyps applying markers of squamous cell carcinogenesis.

Pathol Res Pract 2018 Nov 10. Epub 2018 Nov 10.

Faculty of Medicine, University of Rijeka, Rijeka, Croatia.

Objective: The aim of the study was to perform a pathohistological and immunohistochemical analysis of squamous cell (SC) carcinogenesis markers on epithelial linings of vocal cord polyps. The vocal box, being a heavily burdened organ with intensive cell renewal and regenerative processes, is therefore a favourable environment for constant epithelial growth and hyperplasia. In our ongoing projects on laryngeal carcinogenesis and research on laryngeal tissue, we encountered atypia on diagnosed nodules and polyps that are usually considered as benign formations, resulting from the above-mentioned cell renewal and regeneration, which lead to further investigation. Read More

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November 2018
4 Reads

Comparison of I-gel for general anesthesia in obese and nonobese patients.

Saudi J Anaesth 2018 Oct-Dec;12(4):535-539

Department of Emergency Medicine, King George's Medical University, Lucknow, Uttar Pradesh, India.

Context: I-gel is a second-generation supraglottic airway device. Despite several studies on i-gel, there are very few studies on the use of i-gel in obese patients.

Aims: The aim of the study was to compare the clinical performance of i-gel between obese and nonobese patients. Read More

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November 2018
5 Reads

Use of the C-MAC Macintosh 0 Blade for Intubation of Infants in the Emergency Department.

Pediatr Emerg Care 2018 Nov 12. Epub 2018 Nov 12.

From the Division of Emergency Medicine, Boston Children's Hospital, Harvard Medical School, Boston, MA.

First-pass success rates during intubation of infants in the emergency department have been shown to be low. Video laryngoscopy is being increasingly used during advanced airway management in the emergency department, but available data have not supported improved outcomes with use in pediatrics. The newly available Macintosh size 0 (curved) blade for the C-MAC video laryngoscope offers a narrower blade for use in infants. Read More

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November 2018
1 Read

NSAIDs-hypersensitivity often induces a blended reaction pattern involving multiple organs.

Sci Rep 2018 Nov 12;8(1):16710. Epub 2018 Nov 12.

Allergy Unit, IBIMA-Regional University Hospital of Malaga-UMA, Malaga, Spain.

Non-steroidal anti-inflammatory drugs (NSAIDs)-induced hypersensitivity reactions are classified by the European Network on Drug Allergy (ENDA) as either cross-reactive or selective. The former is the most frequent type and includes patients with exclusively respiratory symptoms (NSAIDs-exacerbated respiratory disease, NERD) or exclusively cutaneous symptoms: NSAIDs-induced urticaria/angioedema (NIUA); and NSAIDs-exacerbated cutaneous disease (NECD). However, although not reflected in the current classification scheme (ENDA), in clinical practice a combination of both skin and respiratory symptoms or even other organs such as gastrointestinal tract symptoms (mixed or blended reactions) is frequently observed. Read More

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November 2018
4 Reads

Endoscopic lateralization of the vocal fold.

Eur Ann Otorhinolaryngol Head Neck Dis 2018 Nov 9. Epub 2018 Nov 9.

Clinique universitaire d'ORL et chirurgie cervico-faciale, hôpital Nord Michallon, CHU de Grenoble, CS 10217, 38043 Grenoble cedex 9, France; Faculté de médecine, université Grenoble Alpes, Domaine de la Merci, BP 170, 38042 Grenoble cedex 9, France; UGA, UMR, CNRS 5309, Inserm 1209, institut pour l'avancée des Biosciences, site Santé, Allée des Alpes, 38700 La Tronche, France; Division of Otolaryngology, Department of Surgery, University of Alabama at Birmingham, Alabama, USA. Electronic address:

Vocal fold paralysis in adduction can result in significant breathing difficulties. Techniques such as vocal fold lateralization and/or arytenoidopexy help to improve respiratory function in this setting. These techniques require open approach or specific instruments. Read More

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November 2018
6 Reads

Erratum of "Laryngeal electromyography in dysphonic patients with incomplete glottic closure".

Braz J Otorhinolaryngol 2018 Nov - Dec;84(6):806

Professor Titular pelo Departamento de Otorrinolaringologia e Cirurgia de Cabeça e Pescoço da Universidade Federal de São Paulo/Escola Paulista de Medicina (Presidente da IFOS (International Federation of ORL Societies)), Universidade Federal de São Paulo/Escola Paulista de Medicina.

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November 2018

Glottic exposure for transoral laser microsurgery: Proposal of a mini-version of the laryngoscore.

Laryngoscope 2018 Nov 8. Epub 2018 Nov 8.

Department of Otorhinolaryngology-Head and Neck Surgery, University of Genoa, Genoa, Italy.

Objectives: Good laryngeal exposure (GLE) is typically regarded as an essential prerequisite for transoral laser microsurgery (TLM). The Laryngoscore is a preoperative scoring system aimed at predicting glottic visualization through the laryngoscope using easy patient-derived parameters. However, the presence of subjective variables may hamper its reliability and reproducibility. Read More

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November 2018
5 Reads

[Vocal Changes and Laryngeal Modifications in the Elderly (Presbyphonia and Presbylarynx)].

Laryngorhinootologie 2018 Nov 7;97(11):772-776. Epub 2018 Nov 7.

In about 20 % of the population older than 60 years of age, voice problems (presbyphonia) are manifest, often combined with hearing deficits (presbyacusis), swallowing disorders (presbyphagia), dizziness (presbyvertigo) and/or impaired vision (presbyopia).The singing voice is afflicted more often, earlier and more severely than the speaking voice. But it is not just the vocal quality and capacity that are affected. Read More

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November 2018
4 Reads

[The morphplogical and its influencing factors research after supracricoid partial laryngectory with cricohyoidoepiglottopexy].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Oct;32(20):1584-1587

Department of Otolaryngology Head and Neck Surgery, the First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, China.

The aim of this study for observing laryngeal morphology, and motion characteristics after supracricoid partial laryngectomy with cricohyoidoepiglottopexy(SCPL-CHEP),exploring the relevant factors affecting the morphology of new laryngeal. Choose 46 cases of patients with laryngeal cancer for SCPL-CHEP as the object of study, dynamic laryngoscope were performed in all the patients, to observe the movement of laryngeal pronunciation (neoglottis closure , supraglottic situation) . Combined with the patient's clinical data, the relevant factors that may affect the pronunciation and movement characteristics of the new throat were analyzed. Read More

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October 2018
3 Reads

Airway Anomalies.

Clin Perinatol 2018 Dec 11;45(4):597-607. Epub 2018 Sep 11.

Department of Otolaryngology Head and Neck Surgery, University of Cincinnati, 3333 Burnet Avenue, Cincinnati, OH 45229, USA.

This article reviews congenital anomalies involving the larynx and trachea, including congenital subglottic stenosis, laryngeal webs, laryngeal cleft, and tracheal stenosis. Presenting signs and symptoms, prevailing surgical repair techniques, and postoperative care are discussed. Read More

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December 2018
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Transoral Robotic Surgery Total Laryngectomy.

ORL J Otorhinolaryngol Relat Spec 2018 5;80(3-4):171-177. Epub 2018 Nov 5.

Department of Otolaryngology Head and Neck Surgery, CHU UCL Dinant Godinne, Yvoir, Belgium.

Objective: The aim of our study is to demonstrate our technique for performing transoral robotic surgical total laryngectomy (TORS-TL) with the use of the da Vinci robotic system.

Materials And Methods: We provide a comprehensive description of the TORS-TL operative techniques. Two fresh-frozen human cadavers were selected after ethics approval to describe the appropriate step-by-step surgical resection. Read More

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November 2018
4 Reads

Tracheal intubation with channeled vs. non-channeled videolaryngoscope blades.

Rom J Anaesth Intensive Care 2018 Oct;25(2):97-101

Institute of Anaesthesiology, Institute of Physiology, University and University Hospital Zurich, Switzerland.

Study Objective: Videolaryngoscopes can be fitted either with channeled or non-channeled blades, which may result in a different performance and success of tracheal intubation. We investigated the characteristics of the two different blade types of the commercially available KingVision™ videolaryngoscope.

Design: A prospective, randomized, single center investigation study in a urological operation unit of a tertiary hospital. Read More

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October 2018

Lethal manifestations of angioedema.

Forensic Sci Med Pathol 2018 Nov 3. Epub 2018 Nov 3.

Forensic Science SA, 21 Divett Place, Adelaide, 5000, Australia.

An 86-year-old woman with a history of angioedema was found dead at her home address. She had recently complained of a swollen tongue. At autopsy the tongue was grossly edematous, protruding from the mouth. Read More

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November 2018
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Comparison of video laryngoscopy versus direct laryngoscopy for intubation in emergency department patients with cardiac arrest: A multicentre study.

Resuscitation 2018 Oct 29. Epub 2018 Oct 29.

Department of Emergency Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA; Harvard Medical School, Boston, Massachusetts, USA.

Aim: To compare the tracheal intubation performance between video laryngoscopy (VL) and direct laryngoscopy (DL) in patients with cardiac arrest in the ED.

Methods: This is an analysis of the data from a prospective, multicentre study of 15 EDs in Japan. We included consecutive adult patients with cardiac arrest who underwent intubation with VL or DL from 2012 through 2016. Read More

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October 2018

Utility of Routine Spirometry Measures for Surveillance of Idiopathic Subglottic Stenosis.

JAMA Otolaryngol Head Neck Surg 2018 Nov 1. Epub 2018 Nov 1.

Department of Otolaryngology-Head and Neck Surgery, University of Virginia, Charlottesville.

Importance: Because of the recurrent nature of idiopathic subglottic stenosis, routine follow-up is necessary for monitoring progression of stenosis. However, no easily accessible, standardized objective measure exists to monitor disease progression.

Objective: To determine whether peak expiratory flow (PEF) can be used as a reliable and easily accessible biometric indicator of disease progression relative to other validated spirometry measures in patients with idiopathic subglottic stenosis. Read More

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November 2018
3 Reads