922 results match your criteria Glottic Stenosis


Emergency tracheotomy and subsequent tracheal resection and anastomosis in a blue crane ().

J Am Vet Med Assoc 2020 Jun;256(11):1262-1267

Case Description: A 7-year-old female blue crane () was initially evaluated after it had suddenly developed signs of respiratory distress following aspiration of a rock. Emergency tracheotomy had been performed, and the rock had been removed from the proximal cervical portion of the trachea. Fifty-one days later, the clinical signs had returned and the crane was reevaluated. Read More

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http://dx.doi.org/10.2460/javma.256.11.1262DOI Listing

Idiopathic subglottic stenosis: a review.

J Thorac Dis 2020 Mar;12(3):1100-1111

Department of Pulmonary Medicine, Respiratory Institute, Cleveland Clinic, Cleveland, OH, USA.

Idiopathic subglottic stenosis (iSGS) is a fibrotic disease of unclear etiology that produces obstruction of the central airway in the anatomic region under the glottis. The diagnosis of this entity is difficult, usually delayed and confounded with other common respiratory diseases. No apparent etiology is identified even after a comprehensive workup that includes a complete history, physical examination, pulmonary function testing, auto-antibodies, imaging studies, and endoscopic procedures. Read More

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http://dx.doi.org/10.21037/jtd.2019.11.43DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139051PMC

Evone® Flow-Controlled Ventilation During Upper Airway Surgery: A Clinical Feasibility Study and Safety Assessment.

Front Surg 2020 28;7. Epub 2020 Feb 28.

Otorhinolaryngology, Head and Neck Surgery, University Hospitals Leuven, Leuven, Belgium.

During upper airway surgery in a narrowed airway due to tumor or stenosis, safe ventilation, good laryngotracheal exposure, and preservation of an adequate surgical working space are of paramount importance. This can be achieved by small-lumen ventilation such as High Frequency Jet Ventilation (HFJV). However, this technique has major drawbacks, such as air-trapping and desaturation in patients with poor pulmonary reserve. Read More

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http://dx.doi.org/10.3389/fsurg.2020.00006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058692PMC
February 2020

Posterior Glottic Stenosis Type I: Clinical Presentation and Postoperative Course.

Ear Nose Throat J 2020 Mar 6:145561320908482. Epub 2020 Mar 6.

Department of Otolaryngology-Head and Neck Surgery, Virginia Commonwealth University, Richmond, VA, USA.

Posterior glottic stenosis (PGS) is a process that results in partial or total fixation of the vocal folds. Type I PGS (PGS-1) is an uncommon clinical entity that results from an interarytenoid adhesion/scar band that is separate from the posterior interarytenoid mucosa. We present a case series of patients with PGS-1 treated at our institution to contribute to the understanding of this complex clinical entity. Read More

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http://dx.doi.org/10.1177/0145561320908482DOI Listing

Bilateral vocal fold immobility: Clinical findings of ten cases and suggested treatment options.

Auris Nasus Larynx 2020 Feb 26. Epub 2020 Feb 26.

Department of Otolaryngology-Head and Neck Surgery, Yokohama City University School of Medicine, Kanagawa, Japan.

Objective: To present the clinical findings of 10 cases of bilateral vocal fold immobility (adducted type) and suggest potential treatment options.

Methods: This retrospective study included 10 patients who underwent tracheostomy for restricted airway due to bilateral vocal fold immobility of the adducted type during the period from 2007 to 2017. All 10 patients underwent unilateral laterofixation surgery with or without additional arytenoidectomy using a CO laser. Read More

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http://dx.doi.org/10.1016/j.anl.2020.02.005DOI Listing
February 2020

[Effect of partial cricotracheal resection and extended cricotracheal resection for severe laryngotracheal stenosis].

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2020 Feb;55(2):94-97

Department of Otorhinolaryngology Head and Neck Surgery, Tangdu Hospital, Air Force Medical University, Xi'an 710038, China.

To assess the outcomes of partial cricotracheal resection (CTR) and extended cricotracheal resection (ECTR) for severe laryngotracheal stenosis. From November 2009 to September 2017, 18 patients underwent CTR and ECTR at the Department of Otorhinolaryngology Head and Neck Surgery, Tangdu Hospital, Air Force Medical University for severe laryngotracheal stenosis were reviewed retrospectively. There were 12-male and 6-female patients, with the age ranged from 4 to 56 years (median 25 years). Read More

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http://dx.doi.org/10.3760/cma.j.issn.1673-0860.2020.02.003DOI Listing
February 2020

Endoscopic Preoperative Assessment, Classification of Stenosis, Decision-Making.

Front Pediatr 2019 8;7:532. Epub 2020 Jan 8.

IRCCS Ospedale Policlinico San Martino, Genoa, Italy.

Pediatric Laryngo-Tracheal Stenosis (LTS) comprises different conditions that require precise preoperative assessment and classification. According to the guidelines, the optimal diagnostic work-up of LTS patients relies both on a comprehensive anamnesis and on endoscopic and radiological assessments. All the causes of LTS result in an impairment in airflow, mucociliary clearance, phonation, and sometimes in swallowing disorders. Read More

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http://dx.doi.org/10.3389/fped.2019.00532DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6960172PMC
January 2020

Effect of Unilateral Cordotomy on Perception of Dysphagia.

Ann Otol Rhinol Laryngol 2020 Jun 30;129(6):536-541. Epub 2019 Dec 30.

Department of Otolaryngology, School of Medicine, University of Colorado, Aurora, CO, USA.

Objectives: CO laser medial transverse cordotomy is a permanent static procedure performed to achieve adequate functional airway in cases of posterior glottic stenosis and bilateral vocal fold paralysis. Although it is the preferred method to manage long-term bilateral vocal fold immobility, it is widely believed that cordotomy has the potential to cause aspiration. The minimal existing data on the effect surgical enlargement of the glottic airway on swallowing function is heterogeneous. Read More

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http://dx.doi.org/10.1177/0003489419898711DOI Listing

Laryngeal Web in the Pediatric Population: Evaluation and Management.

Otolaryngol Head Neck Surg 2020 Feb 17;162(2):234-240. Epub 2019 Dec 17.

Department of Otolaryngology, Children's National Medical Center, Washington, DC, USA.

Objective: To discuss the presentation, evaluation, and management of pediatric laryngeal web.

Study Design: Retrospective case series.

Setting: Single tertiary care center. Read More

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http://dx.doi.org/10.1177/0194599819893985DOI Listing
February 2020

Glottic adhesion and stenosis in a patient with systemic lupus erythematosus.

Lupus 2020 Jan 12;29(1):98-99. Epub 2019 Dec 12.

Department of Otorhinolaryngology/Head and Neck Surgery, Hamamatsu University School of Medicine, Japan.

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http://dx.doi.org/10.1177/0961203319894386DOI Listing
January 2020

Surveillance endoscopy after tracheostomy placement in children: Findings and interventions.

Laryngoscope 2020 May 31;130(5):1327-1332. Epub 2019 Oct 31.

Department of Pediatric Otolaryngology-Head and Neck Surgery, Virginia Mason Medical Center, Seattle, Washington, U.S.A.

Objectives/hypothesis: The Seattle Children's Hospital implemented the Trach Safe Initiative to improve airway safety in tracheostomy-dependent children (TDC). A key tenet of this initiative is surveillance endoscopy. The objectives of this study were to describe the prevalence of abnormal airway changes in TDC, identify risk factors for these changes, and describe the frequency of airway interventions. Read More

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http://dx.doi.org/10.1002/lary.28247DOI Listing
May 2020
1 Read

A Modified Laryngeal Stent for Glotto-Subglottic Stenosis: A Novel Stent for Better Outcomes.

Ear Nose Throat J 2019 Oct 22:145561319883074. Epub 2019 Oct 22.

Department of Otorhinolaryngology-Head and Neck Surgery, Montefiore Medical Center, Einstein College of Medicine, Bronx, NY, USA.

Management of laryngotracheal stenosis is challenging and laryngotracheal stenosis is generally managed with laryngotracheal reconstruction. Stents are often used as part of the reconstructive surgery. Although most stents adequately stabilize the reconstruction during healing, they often do a poor job of mimicking glottic anatomy, particularly the anterior glottis. Read More

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http://dx.doi.org/10.1177/0145561319883074DOI Listing
October 2019
8 Reads

[Clinical study about anatomical and functional reconstruction for frontolateral vertical partial laryngectomy with ultrathin titanium mesh and fascia flap from the strap muscles].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2019 Oct;33(10):958-960

Department of Otorhinolaryngology Head and Neck Surgery,the First Affiliated Hospital of Nanchang University,Nanchang,330006,China.

To investigate the effect of laryngeal reconstruction in functional and anatomical aspect with ultrathin titanium mesh and myofascial flap in patients underwent frontolateral vertical partial laryngectomy with T2 and T3 glottic laryngeal carcinoma. Ten patients with T2 and T3 glottic laryngeal carcinoma underwent frontolateral vertical partial laryngectomy in different range. The ultrathin titanium mesh was shaped up according to the form of thyroid cartilage in operation while the thyroid perichondrium membrane combined with straped myofascial flap was lined under the titanium mesh to restore the laryngeal cavity space. Read More

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http://dx.doi.org/10.13201/j.issn.1001-1781.2019.10.014DOI Listing
October 2019
1 Read

Decoding supraglottic stenosis.

Eur Arch Otorhinolaryngol 2020 Jan 10;277(1):293-300. Epub 2019 Oct 10.

Department of Otorhinolaryngology, Lausanne University Hospital, Rue du Bugnon, 1005, Lausanne, Switzerland.

Objective: Supraglottic stenosis (SPGS) is a rare condition and little is known about its optimal management. Its etiologies are varied and depend on the age group. Here, we review our institution's series of patients and propose treatment strategies for SPGS. Read More

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http://dx.doi.org/10.1007/s00405-019-05677-1DOI Listing
January 2020

Surgical management of acquired anterior glottic web: a systematic review.

J Laryngol Otol 2019 Sep 18:1-8. Epub 2019 Sep 18.

Department of Otolaryngology, University Hospital of Ferrara, Italy.

Background: Acquired anterior glottic web poses a significant challenge to laryngologists given its propensity to recur following treatment, and there are a wide variety of described techniques.

Methods: A systematic review of the medical literature was undertaken in order to identify all articles pertaining to the management of acquired anterior glottic web.

Results: Thirteen studies meeting the inclusion criteria were identified and analysed. Read More

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http://dx.doi.org/10.1017/S0022215119001920DOI Listing
September 2019

Cricotracheal resection for adult subglottic stenosis: Factors predicting treatment failure.

Laryngoscope 2019 Sep 9. Epub 2019 Sep 9.

Department of Otolaryngology-Head and Neck Surgery, University Health Network, Toronto, Ontario, Canada.

Objectives/hypothesis: Identify predictors of decannulation failure after cricotracheal resection (CTR) and thyrotracheal anastomosis (TTA) in patients with subglottic stenosis (SGS).

Study Design: Retrospective cohort study.

Methods: Charts of patients undergoing CTR and TTA for SGS at the University Health Network, Toronto, Ontario, Canada between 1988 and 2017 were reviewed. Read More

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http://dx.doi.org/10.1002/lary.28273DOI Listing
September 2019
4 Reads

Unconventional delivery of inhaled nitric oxide during endoscopic laryngeal tracheal reconstruction in a child with pulmonary arterial hypertension: A case report.

Paediatr Anaesth 2019 11 17;29(11):1146-1147. Epub 2019 Sep 17.

Division of Pediatric Otolaryngology, Department of Otolaryngology, Columbia University Medical Center, New York, NY, USA.

Endoscopic laryngeal tracheal reconstruction was performed on a child with glottic stenosis and pulmonary arterial hypertension. The surgical repair was performed while delivering inhaled nitric oxide via the ventilating port of a suspension laryngoscope with the patient maintaining spontaneous respirations. The surgery was accomplished without complications. Read More

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http://dx.doi.org/10.1111/pan.13732DOI Listing
November 2019
2 Reads

Early medical therapy for acute laryngeal injury (ALgI) following endotracheal intubation: a protocol for a prospective single-centre randomised controlled trial.

BMJ Open 2019 07 27;9(7):e027963. Epub 2019 Jul 27.

Department of Otolaryngology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.

Introduction: Respiratory failure requiring endotracheal intubation accounts for a significant proportion of intensive care unit (ICU) admissions. Little attention has been paid to the laryngeal consequences of endotracheal intubation. Acute laryngeal injury (ALgI) after intubation occurs at the mucosal interface of the endotracheal tube and posterior larynx and although not immediately manifest at extubation, can progress to mature fibrosis, restricted glottic mobility and clinically significant ventilatory impairment. Read More

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http://dx.doi.org/10.1136/bmjopen-2018-027963DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6661707PMC
July 2019
2 Reads

Feasibility and potential of three-dimensional printing in laryngotracheal stenosis.

J Laryngol Otol 2019 Jun 24;133(6):530-534. Epub 2019 Jun 24.

Department of Pediatric Otolaryngology,Louisiana State University,Children's Hospital New Orleans,USA.

Background: The use of three-dimensional printing has been rapidly expanding over the last several decades. Virtual surgical three-dimensional simulation and planning has been shown to increase efficiency and accuracy in various clinical scenarios.

Objectives: To report the feasibility of three-dimensional printing in paediatric laryngotracheal stenosis and discuss potential applications of three-dimensional printed models in airway surgery. Read More

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http://dx.doi.org/10.1017/S0022215119001208DOI Listing
June 2019
13 Reads

Vocal fold fixation due to proximal stenosis progression complicating idiopathic subglottic stenosis.

Eur Arch Otorhinolaryngol 2019 Aug 11;276(8):2293-2300. Epub 2019 Jun 11.

Department of Otorhinolaryngology-Head and Neck Surgery, Auckland City Hospital, Auckland, New Zealand.

Purpose: This study examined the incidence and risk factors for vocal fold fixation due to proximal progression of idiopathic subglottic stenosis (ISS) over the course of serial treatments.

Methods: Records of 22 consecutive patients with ISS treated between 2004 and 2016 were retrospectively reviewed. Patient, stenosis, and treatment details were recorded. Read More

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http://dx.doi.org/10.1007/s00405-019-05494-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6616212PMC
August 2019
9 Reads

Unilateral vs Bilateral Supraglottoplasty: A Meta-analysis of Rates of Return to Surgery and Supraglottic Stenosis.

Otolaryngol Head Neck Surg 2019 11 11;161(5):742-753. Epub 2019 Jun 11.

Otolaryngology-Head and Neck Surgery, Division of Sleep Surgery and Medicine, Tripler Army Medical Center, Honolulu, Hawaii, USA.

Objective: To perform a systematic review with meta-analysis of data to determine the rates of repeat surgery and supraglottic stenosis in unilateral versus bilateral supraglottoplasty for laryngomalacia.

Data Sources: PubMed/Medline, Cochrane Central, Scopus, Google Scholar, Web of Science, and Embase.

Review Methods: Databases were searched through January 30, 2018. Read More

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http://dx.doi.org/10.1177/0194599819847644DOI Listing
November 2019
1 Read

Type I Posterior Glottic Stenosis: Natural History and In-Office Management.

Ann Otol Rhinol Laryngol 2019 Nov 4;128(11):1073-1077. Epub 2019 Jun 4.

Sean Parker Institute for the Voice, Department of Otolaryngology-Head and Neck Surgery, Weill Cornell Medical College/New York-Presbyterian Hospital, New York, NY, USA.

Objectives: To review the natural history of type I posterior glottic stenosis (PGS-I) and its treatment outcomes through a case presentation and demonstrate the feasibility of in-office management of PGS-I.

Methods: The case of a middle-aged woman who developed PGS-I after prolonged intubation is presented. A review of the literature on management and treatment outcomes of PGS-I is also performed. Read More

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http://dx.doi.org/10.1177/0003489419854777DOI Listing
November 2019
4 Reads
1.054 Impact Factor

[Minimally invasive treatment of postintubation stenosis by use of Ultra Dream Pulse Laser and steroid-mitomycin in a 4-year-old girl].

Orv Hetil 2019 May;160(20):792-796

Fül-Orr-Gégészeti és Fej-Nyaksebészeti Klinika, Szegedi Tudományegyetem, Általános Orvostudományi Kar Szeged.

Postintubation stenosis is a frequent complication of long-term endotracheal anesthesia. In the last few decades, its incidence showed an increasing tendency particularly among children and premature infants. It mostly affects the subglottic area and avoidance of a tracheotomy could lead to better life quality of the patient. Read More

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http://dx.doi.org/10.1556/650.2019.31361DOI Listing
May 2019
6 Reads

Laryngotracheal Microbiota in Adult Laryngotracheal Stenosis.

mSphere 2019 05 1;4(3). Epub 2019 May 1.

Department of Surgery, University of Wisconsin-Madison, Madison, Wisconsin, USA

Laryngotracheal stenosis is an obstructive respiratory disease that leads to voicing difficulties and dyspnea with potential life-threatening consequences. The majority of incidences are due to iatrogenic etiology from endotracheal tube intubation; however, airway scarring also has idiopathic causes. While recent evidence suggests a microbial contribution to mucosal inflammation, the microbiota associated with different types of stenosis has not been characterized. Read More

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http://dx.doi.org/10.1128/mSphereDirect.00211-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6495342PMC
May 2019
16 Reads

Computational Fluid Dynamics Analysis of Surgical Approaches to Bilateral Vocal Fold Immobility.

Laryngoscope 2020 Feb 18;130(2):E57-E64. Epub 2019 Mar 18.

Department of Mechanical Engineering, School of Engineering, Vanderbilt University, Nashville, Tennessee.

Objectives: Bilateral vocal fold immobility (BVFI) is a rare and life-threatening condition in which both vocal folds are fixed, resulting in airway obstruction associated with life-threatening respiratory compromise. Treatment of BVFI is largely surgical and remains an unsatisfactory compromise between voice, breathing, and swallowing. No comparisons between currently employed techniques currently exist. Read More

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http://dx.doi.org/10.1002/lary.27925DOI Listing
February 2020
4 Reads

A Method for Reconstruction of Anterior Commissure Glottal Webs With Endoscopic Fibro-Mucosal Flaps.

Ann Otol Rhinol Laryngol 2019 Mar;128(3_suppl):82S-93S

1 Department of Surgery, Harvard Medical School, Boston, MA, USA.

Background:: Anterior-commissure (AC) cicatrization and web formation is a difficult problem that can result from a variety of clinical scenarios. An advancement-rotation flap utilizing papillomatous epithelium and subepithelial fibrous tissue has been previously described. For patients in whom there was not excessive redundant papillomatosis covering the AC web, including other clinical scenarios, a microlaryngoscopic procedure was designed to lengthen the glottal/subglottal aperture using substantial local fibro-mucosal tissue. Read More

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http://dx.doi.org/10.1177/0003489418820031DOI Listing
March 2019
33 Reads

Glottic Stenosis: An Anatomic Analysis and New Treatment With a Self-Retaining Interarytenoid Spring.

Ann Otol Rhinol Laryngol 2019 Mar;128(3_suppl):94S-105S

1 Department of Surgery, Harvard Medical School, Boston, MA, USA.

Introduction:: Endotracheal (ET) intubation is a common cause of acquired glottic stenosis. Severe cases often require an irreversible arytenoidectomy/cordectomy, which typically results in poor voice quality. Adult human cadaver larynges were studied to gain insights about ET tube-induced posterior glottic injuries, hoping to create a less invasive remedy. Read More

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http://dx.doi.org/10.1177/0003489418802284DOI Listing
March 2019
17 Reads

An evaluation of arytenoid prolapse following laryngotracheal reconstruction.

Laryngoscope 2020 Jan 5;130(1):247-251. Epub 2019 Mar 5.

Department of Otolaryngology, Children's National Health System, Washington, DC, U.S.A.

Objectives/hypothesis: Laryngotracheal reconstruction (LTR) is a collection of procedures used to treat pediatric laryngotracheal stenosis. Arytenoid prolapse is a potential postoperative complication that may lead to upper airway obstruction. This study investigates the incidence, risk factors, and need for surgical intervention for post-LTR arytenoid prolapse. Read More

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http://dx.doi.org/10.1002/lary.27864DOI Listing
January 2020
12 Reads

Implementation of the European Laryngological Society classification for pediatric benign laryngotracheal stenosis: a multicentric study.

Eur Arch Otorhinolaryngol 2019 Mar 22;276(3):785-792. Epub 2019 Feb 22.

Department of Otorhinolaryngology Head and Neck Surgery, Katharinenhospital, Kriegsbergstrasse 60, 70174, Stuttgart, Germany.

Purpose: The European Laryngological Society (ELS) has published a revised classification for benign laryngotracheal stenosis (LTS), based on their degree, longitudinal extension, and associated comorbidities. We retrospectively applied this classification to pediatric patients treated in four referral centers to assess its reliability in predicting surgical outcomes.

Methods: We included 191 pediatric LTS patients treated by segmental resection, restaged according to the degree of stenosis (I-IV according to Myer-Cotton grading system), number of subsites involved ("a" to "d" for 1-4 subsites among supraglottis, glottis, subglottis and trachea), and presence of systemic comorbidity ("+" sign). Read More

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http://dx.doi.org/10.1007/s00405-019-05353-4DOI Listing
March 2019
7 Reads

Clinical outcomes of end-flexible-rigidscopic transoral surgery (E-TOS) in patients with T1-selected T3 pharyngeal and supraglottic cancers.

Acta Otolaryngol 2019 Feb 21;139(2):187-194. Epub 2019 Feb 21.

a Otolaryngology-Head & Neck Surgery , Osaka Red Cross Hospital , Osaka , Japan.

Background: Endoscopic laryngo-pharyngeal surgery (ELPS), which is a transoral minimally invasive surgery using a gastrointestinal endoscope and a curved laryngopharyngeal retractor, is effective to treat primary lesions of superficial laryngopharyngeal cancers. To extend concepts of ELPS to invasive laryngopharyngeal cancers, we developed end-flexible-rigidscopic transoral surgery (E-TOS) from ELPS by changing a gastrointestinal endoscope to a flexible-tip rigid endoscope.

Aims/objectives: To retrospectively evaluate oncological outcomes and laryngopharyngeal functional preservation of E-TOS in patients with T1-selected T3 laryngopharyngeal cancers. Read More

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http://dx.doi.org/10.1080/00016489.2018.1532106DOI Listing
February 2019
9 Reads

Novel, anatomically appropriate balloon dilation technique of the glottis to treat posterior glottic stenosis in a 3D-printed model.

Laryngoscope 2019 10 18;129(10):2239-2243. Epub 2019 Feb 18.

Department of Otolaryngology, University of Pittsburgh, Pittsburgh, Pennsylvania, U.S.A.

Objective: Posterior glottic stenosis (PGS) often requires a destructive surgical treatment. Early PGS treatment involves glottic dilation to reduce airway constriction associated with chronic PGS. Round laryngeal dilation may not optimize posterior glottic dilation due to the teardrop shape of the glottis and may injure vocal fold tissue. Read More

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http://dx.doi.org/10.1002/lary.27524DOI Listing
October 2019
7 Reads

Radiotherapy in advanced glottic laryngeal carcinoma in a patient with Wegener's granulomatosis: how much radiation dose is needed?

Onco Targets Ther 2019 23;12:753-757. Epub 2019 Jan 23.

Radiation Oncology Unit, San Giuseppe Moscati Hospital, Taranto, Italy,

Wegener's granulomatosis (WG) is an autoimmune disorder characterized by necrotizing granulomas involving mainly the upper-lower respiratory and renal tracts, albeit a potentially life-threatening involvement of other body parts is not rare. Furthermore, there are several reports accounting for an increased risk of solid malignancies due to the autoimmune disease per se, or the immunosuppressive therapies. Among treatments, radiotherapy could be a therapeutic option as proven by its use in typical WG lesions such as solitary granulomas or subglottic stenosis, successfully treated with low radiation dose. Read More

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http://dx.doi.org/10.2147/OTT.S182011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352862PMC
January 2019
7 Reads

Association Between Red Blood Cell Distribution Width and Outcomes of Open Airway Reconstruction Surgery in Adults.

JAMA Otolaryngol Head Neck Surg 2019 03;145(3):210-215

Surgical Outcomes Center for Kids, Vanderbilt University Medical Center. Nashville, Tennessee.

Importance: Airway reconstruction for adults with laryngotracheal stenosis (LTS) is directed toward improving airway caliber to mitigate the patient's dyspnea and achieve prosthesis-free breathing (ie, without tracheostomy, intraluminal stent, or T-tube). Despite the importance of preoperative risk stratification to minimize postoperative complications, consensus on an objective predictive algorithm for open airway reconstruction is lacking.

Objective: To determine whether the ability to achieve a prosthesis-free airway in adults after open airway reconstruction is associated with red blood cell distribution width (RDW) at the time of surgery. Read More

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http://dx.doi.org/10.1001/jamaoto.2018.3793DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6439750PMC
March 2019
10 Reads

Establishment of an immortalized human subglottic epithelial cell line.

Laryngoscope 2019 11 8;129(11):2640-2645. Epub 2019 Jan 8.

Institute of Cellular Medicine, Newcastle upon Tyne, United Kingdom.

Objective: Translational research into subglottic disease is restricted by the availability of primary human tissue originating from this subsite. Primary epithelial cells are also limited by their inability to survive beyond several divisions in culture outside of the body. Specific subglottic cell lines, useful for in vitro studies, have not yet been described. Read More

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http://dx.doi.org/10.1002/lary.27761DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6849794PMC
November 2019
1 Read

Antifibrotic effect of mitomycin-C on human vocal cord fibroblasts.

Laryngoscope 2019 07 7;129(7):E255-E262. Epub 2019 Jan 7.

Department of Oto-Rhino-Laryngology and Head & Neck Surgery, Szeged, Hungary.

Objective: Acquired laryngotracheal stenosis is a potentially life-threatening situation and a very difficult and challenging problem in laryngology. Therefore, new trends and innovative approaches based on antifibrotic drugs and minimally invasive regimens are being developed to attenuate laryngotracheal fibrosis and scarring. The purpose of this study was to examine the efficacy of mitomycin-C (MMC) to reverse the transforming growth factor (TGF)-β-induced differentiation of MRC-5 fibroblast and human primary vocal cord fibroblasts to reveal the possible applicability of MMC to laryngotracheal fibrotic conditions. Read More

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http://dx.doi.org/10.1002/lary.27657DOI Listing
July 2019
5 Reads

The glottis is not round: Teardrop-shaped glottic dilation for early posterior glottic stenosis.

Laryngoscope 2019 06 27;129(6):1428-1432. Epub 2018 Dec 27.

Department of Otolaryngology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, U.S.A.

Objectives: Posterior glottic stenosis (PGS) results in severe derangement of laryngeal configuration and function with significant morbidity as a sequalae. Presently, there is no treatment for patients with "early" PGS. Dilation is often used for stenotic disease, but present dilation methods are limited to a round shape and the glottis is a sector (teardrop-shaped). Read More

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http://dx.doi.org/10.1002/lary.27594DOI Listing
June 2019
3 Reads

Systemic safety of serial intralesional steroid injection for subglottic stenosis.

Laryngoscope 2019 07 24;129(7):1634-1639. Epub 2018 Dec 24.

Department of Otolaryngology-Head and Neck Surgery, Monash Health, Clayton, Victoria, Australia.

Objectives/hypothesis: Serial intralesional steroid injection (SILSI) has recently been proposed as an effective scar-modifying therapy for subglottic stenosis (SGS). We aimed to explore the systemic absorption of steroid following SILSI and to characterize the magnitude and chronicity of any effect observed. Specifically, we aimed to show that any effect resolves prior to the next intralesional injection. Read More

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http://dx.doi.org/10.1002/lary.27673DOI Listing
July 2019
3 Reads

Voice Outcomes in Laryngotracheal Stenosis: Impact of the Montgomery T-tube.

Clin Surg 2018 Jan 10;3. Epub 2018 Jan 10.

Department of Otolaryngology, Johns Hopkins University, USA.

Objectives: Montgomery T-tubes enable patients with laryngotracheal stenosis to maintain airway patency. They also restore the ability to phonate in many patients. The primary objective is to compare voice quality of life outcomes in patients before and after Montgomery T-tube placement. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291003PMC
January 2018
3 Reads

Isolated Recovery of Adductor Muscle Function Following Bilateral Recurrent Laryngeal Nerve Injuries.

Laryngoscope 2019 10 13;129(10):2334-2340. Epub 2018 Dec 13.

Department of Otorhinolaryngology-Head and Neck Surgery, University of Szeged, Szeged, Hungary.

Objectives/hypothesis: The aim of this study was to analyze the phoniatric and respiratory outcomes of a subset of bilateral vocal cord paralysis (BVCP) patients who were all treated with unilateral endoscopic arytenoid abduction lateropexy (EAAL). EAAL is a nondestructive, minimally invasive glottis widening operation, which does not damage either the surgically treated or the contralateral vocal cord. Therefore, it does not impair the regeneration potential of the recurrent laryngeal nerve. Read More

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http://dx.doi.org/10.1002/lary.27718DOI Listing
October 2019
8 Reads

Impact of Balloon Diameter on Dilation Outcomes in a Model of Rabbit Subglottic Stenosis.

Laryngoscope 2019 10 13;129(10):2409-2413. Epub 2018 Dec 13.

the Division of Pediatric Otolaryngology-Head and Neck Surgery, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, U.S.A.

Objective: To determine the appropriate balloon size for dilation using a previously described reproducible survival animal model of subglottic stenosis.

Study Design: Prospective animal study.

Methods: We conducted a prospective study including 16 New Zealand White rabbits. Read More

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http://dx.doi.org/10.1002/lary.27574DOI Listing
October 2019
4 Reads
2.032 Impact Factor

Airway Anomalies.

Clin Perinatol 2018 12 11;45(4):597-607. Epub 2018 Sep 11.

Department of Otolaryngology Head and Neck Surgery, University of Cincinnati, 3333 Burnet Avenue, Cincinnati, OH 45229, USA.

This article reviews congenital anomalies involving the larynx and trachea, including congenital subglottic stenosis, laryngeal webs, laryngeal cleft, and tracheal stenosis. Presenting signs and symptoms, prevailing surgical repair techniques, and postoperative care are discussed. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00955108183138
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http://dx.doi.org/10.1016/j.clp.2018.07.002DOI Listing
December 2018
8 Reads

Utility of Routine Spirometry Measures for Surveillance of Idiopathic Subglottic Stenosis.

JAMA Otolaryngol Head Neck Surg 2019 01;145(1):21-26

Department of Otolaryngology-Head and Neck Surgery, University of Virginia, Charlottesville.

Importance: Because of the recurrent nature of idiopathic subglottic stenosis, routine follow-up is necessary for monitoring progression of stenosis. However, no easily accessible, standardized objective measure exists to monitor disease progression.

Objective: To determine whether peak expiratory flow (PEF) can be used as a reliable and easily accessible biometric indicator of disease progression relative to other validated spirometry measures in patients with idiopathic subglottic stenosis. Read More

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http://archotol.jamanetwork.com/article.aspx?doi=10.1001/jam
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http://dx.doi.org/10.1001/jamaoto.2018.2717DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6439814PMC
January 2019
9 Reads

Vocal Fold Motion Recovery in Patients With Iatrogenic Unilateral Immobility: Cervical Versus Thoracic Injury.

Ann Otol Rhinol Laryngol 2019 Jan 20;128(1):44-49. Epub 2018 Oct 20.

1 Department of Surgery, Harvard Medical School, Center for Laryngeal Surgery and Voice Rehabilitation, Massachusetts General Hospital, Boston, MA, USA.

Objectives:: Prognostic information about the return of vocal fold mobility in patients with iatrogenic unilateral vocal fold immobility (UVFI) can help with informed decisions about temporary and permanent treatment options. Although many variables can influence the likelihood of recovery, clinical experience suggests that cervical versus thoracic injury is a determining factor. The purpose of this study was to compare recovery rates from UVFI between cervical and thoracic injuries. Read More

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http://dx.doi.org/10.1177/0003489418808306DOI Listing
January 2019
39 Reads

[Trans-vocal cord prostheses - preliminary experience treating benign laryngotracheal stenosis in adults].

Rev Mal Respir 2019 Jan 16;36(1):49-56. Epub 2018 Oct 16.

Service d'oncologie thoracique, maladies de la Plèvre, pneumologie interventionnelle, hôpital Nord Aix-Marseille université, 13000 Marseille, France; Aix-Marseille université, 13000 Marseille, France.

Introduction: Benign laryngotracheal stenosis is a rare pathology with multiple etiologies, the management of which is complex. This is because of the configuration and proximity of the larynx and the difficulty with surgical approaches, which are potentially mutilating, especially for the management of a benign disease. When surgery is challenging, iterative dilatations of the stricture or the fashioning of a definitive tracheotomy are therapeutic alternatives. Read More

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http://dx.doi.org/10.1016/j.rmr.2018.01.015DOI Listing
January 2019
3 Reads

Height is an independent risk factor for postintubation laryngeal injury.

Laryngoscope 2018 12 16;128(12):2811-2814. Epub 2018 Oct 16.

Department of Otolaryngology Head and Neck Surgery, Nashville, Tennessee.

Objectives/hypothesis: Intubation is an essential component of intensive care, yet it does have potential complications. Posterior glottic stenosis (PGS) is among the most severe sequela. Risk factors are poorly understood. Read More

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http://doi.wiley.com/10.1002/lary.27237
Publisher Site
http://dx.doi.org/10.1002/lary.27237DOI Listing
December 2018
31 Reads

Airway Management During Anesthetic Induction of Secondary Laryngectomy for Recurrent Laryngeal Cancer: Three Cases of Report and Analysis.

Front Med (Lausanne) 2018 19;5:264. Epub 2018 Sep 19.

Department of Anesthesiology, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.

Surgery for laryngeal cancer and the following recurrent tumor growth may further change the anatomy of the airway. Airway management during anesthesia induction is challenging for the patients undergoing secondary surgery due to recurrence of laryngeal cancer or its postoperative complication, but it has never been reported. In this report, we described three cases of anesthetic induction which had different process of airway events. Read More

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https://www.frontiersin.org/article/10.3389/fmed.2018.00264/
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http://dx.doi.org/10.3389/fmed.2018.00264DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157329PMC
September 2018
13 Reads

Surgical Treatment Modalities for Iatrogenic Anterior Glottic Stenosis.

Ann Otol Rhinol Laryngol 2018 Dec 29;127(12):946-952. Epub 2018 Sep 29.

1 Department of Otorhinolaryngology-Head and Neck Surgery, Huashan Hospital, Fudan University, Shanghai, China.

Objectives:: The aim of this study was to describe common iatrogenic causes of anterior glottic stenosis and to investigate the surgical treatment outcomes of 3 different techniques aimed at repairing stenoses and preventing web reformation.

Methods:: Clinical information regarding patient demographics, presentation, etiology, treatment, and follow-up outcomes was obtained retrospectively through a review of patients' records between April 2010 and April 2017. Voice quality was evaluated using grade, roughness, breathiness, asthenia, and strain scale and Voice Handicap Index scores. Read More

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http://journals.sagepub.com/doi/10.1177/0003489418803651
Publisher Site
http://dx.doi.org/10.1177/0003489418803651DOI Listing
December 2018
7 Reads

A novel surgical treatment for posterior glottic stenosis using thyroid ala cartilage - A case report and literature review.

Int J Pediatr Otorhinolaryngol 2018 Nov 1;114:129-133. Epub 2018 Aug 1.

University of Arkansas for Medical Sciences, Department of Otolaryngology, Head and Neck Surgery, Division of Pediatric Otolaryngology, United States.

Posterior glottic stenosis (PGS) describes a laryngeal disorder in which worsening degrees of scarring limit abduction of the vocal folds and/or arytenoids. It can be congenital or acquired. Generally, the acquired form is the result of chronic endotracheal tube trauma to the posterior larynx. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01655876183034
Publisher Site
http://dx.doi.org/10.1016/j.ijporl.2018.07.025DOI Listing
November 2018
9 Reads