Crit Rev Oncol Hematol 2021 Apr 11;160:103298. Epub 2021 Mar 11.
Department of Otorhinolaryngology, Careggi University Hospital, Largo Brambilla 3, 50134, Florence, Italy; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Introduction: Recurrent early glottic cancer (rEGC) poses several issues in terms of timely diagnosis, correct re-staging, and treatment. We want to critically review the latest evidence about rEGC considering its epidemiology, biology, diagnostic challenges, and treatment strategies.
Methods: A systematic search of the literature using PubMed from 1990 to October 31, 2020 was performed. Read More