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    Robotic radiosurgery of head and neck paragangliomas: a single institution experience.
    Asia Pac J Clin Oncol 2017 May 24. Epub 2017 May 24.
    Department of Radiation Oncology, Acibadem University, Istanbul, Turkey.
    Aim: CyberKnife(®) is a robotic stereotactic radiotherapy system. The aim of this study is to evaluate the effectiveness and the safety of CyberKnife(®) on treating head and neck paragangliomas and to report our results.

    Methods: Between March 2009 and June 2014, 12 patients with head and neck paragangliomas have been referred to our clinic: in three cases had jugular paragangliomas, five cases had carotid body paragangliomas and three cases had tympanic paragangliomas. Read More

    Characteristics and prognosis of glomangiopericytomas: A systematic review.
    Head Neck 2017 May 12. Epub 2017 May 12.
    Department of Pathology, Incheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Incheon, Republic of Korea.
    Background: Glomangiopericytoma belongs to the category of borderline/low-malignant-potential tumors of the sinonasal tract, but no studies about prognosis have been reported.

    Methods: To define the characteristics of glomangiopericytoma and to identify its prognostic factors, a systematic review was performed. A total of 337 cases of glomangiopericytomas were analyzed. Read More

    Brace yourself: an unusual case of knee pain, an extradigital glomangioma of the knee.
    Radiol Case Rep 2017 Jun 8;12(2):357-360. Epub 2017 Apr 8.
    Department of Pathology, University of Florida College of Medicine-Jacksonville, Jacksonville, FL 32209, USA.
    The differential diagnosis for knee pain is extensive. Glomus tumors comprise approximately 1.6% of soft-tissue tumors in the extremities. Read More

    [Endovascular treatment of complex vascular pathology in neck and brain region. Case report].
    Orv Hetil 2017 May;158(18):706-710
    Borsod-Abaúj-Zemplén Megyei Kórház és Egyetemi Oktató Kórház Miskolc, Szentpéteri kapu 72-76., 3501.
    Authors present complex multistage endovascular treatment of female patient with an intradural infiltrative, inoperable tumor of the glomus jugulare, a stenosis of the internal carotid artery and an aneurysm of middle cerebri artery. In the literature our case report is the first announcement in which three pathology coexist ipsilateral in one patient and the patient has been treated step by step by endovascular procedures. Beside the endovascular treatment steps they display glomus jugulare tumor's symptoms, staging, treatment options and also the current treatment guidelines of internal carotid artery stenosis and intracranial aneurysms. Read More

    Breast Cancer Metastasis on the Neck Mimicking a Glomus Tumor.
    J Craniofac Surg 2017 May;28(3):e271-e273
    *Department of Otorhinolaryngology, Head and Neck Surgery, Istanbul Medical Faculty, University of Istanbul †Department of Pathology, Istanbul Medical Faculty, University of Istanbul, Istanbul, Turkey.
    Cervical metastases from breast carcinoma are extremely rare after several years of disease-free survival. In this article, a metastatic tumor of the neck originating from a breast carcinoma, which has been treated 14 years ago, is discussed. A case is presented of a 48-year-old female patient with a history of breast carcinoma, which was surgically treated approximately 14 years ago. Read More

    Unusual gastric tumors and tumor-like lesions: Radiological with pathological correlation and literature review.
    World J Gastroenterol 2017 Apr;23(14):2493-2504
    Yuan-Mao Lin, Nai-Chi Chiu, Chien-An Liu, Yi-Hong Chou, Yi-You Chiou, Division of Gastrointestinal Radiology, Department of Radiology, Taipei Veterans General Hospital, Taipei 11217, Taiwan.
    Although gastric tumors have overlapping radiologic appearances, some unusual tumors may present specific imaging features. Using multidetector computed tomography (MDCT), with water as a negative oral contrast agent and intravenous contrast medium, can provide critical information for the diagnosis of gastric diseases. In addition, MDCT can evaluate the involvement of the gastric wall and extragastric extent of the disease, as compared with gastroenteroscopy and double-contrast upper gastrointestinal study. Read More

    Tracheal Glomus Tumor: A Case Report and Review of the Literature.
    Rare Tumors 2017 Mar 28;9(1):6848. Epub 2017 Mar 28.
    Division of Thoracic Surgery, Department of Surgery, University of Pennsylvania, Philadelphia, PA, USA.
    Glomus tumors are rare neoplasms that typically occur within the dermis or subcutis of the subungual space. Primary glomus tumors of the thorax are exceedingly uncommon, thus standard-of-care management is lacking. In this report we describe the management of a patient presenting with a symptomatic glomus tumor of the posterior trachea, and provide a comprehensive review including all documented tracheal glomus tumor reports. Read More

    Pericytic Tumors of the Kidney - A Clinicopathologic Analysis of 17 Cases.
    Hum Pathol 2017 Apr 21. Epub 2017 Apr 21.
    Department of Pathology and Laboratory Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA; Department of Pathology and Laboratory Medicine, University of Tennessee Health Sciences. Electronic address:
    The pericytic (perivascular myoid cell) family of tumors is a distinctive group of mesenchymal neoplasms encountered in superficial sites and only rarely seen in viscera. The pericytic family subtends a spectrum of lesions, namely, glomus tumors and variants; myopericytoma, including myofibroma; and angioleiomyoma. In light of the contemporary classification of pericytic lesions, we identified and reviewed 17 cases of renal pericytic tumors from the files of 6 referral centers. Read More

    Intraneural glomus tumor of "uncertain malignant potential" and with BRAF mutation in the median nerve - an unusual case.
    Clin Neuropathol 2017 Apr 25. Epub 2017 Apr 25.
    A glomus tumor of uncertain malignant potential is defined as a glomus tumor with some, but not all, criteria for malignancy and without a known metastasis. Here, we present a rare example presenting in the median nerve in a 40-year-old woman with a long history of severely impaired left median nerve function. A large panel of immunohistochemical stains excluded other diagnoses, and the designation of a "uncertain malignant potential" was based on the high proliferative activity, the tumor size and location, and the lack of WHO malignancy criteria such as marked nuclear atypia, necrosis, or atypical mitoses. Read More

    Subungual Glomus Tumours: Is Magnetic Resonance Imaging or Ultrasound Necessary for Diagnosis?
    Malays Orthop J 2017 Mar;11(1):47-51
    Department of Orthopaedics, Grande International Hospital Kathmandu, Nepal.
    Introduction: Diagnosis of subungual glomus tumour is mostly based on detailed history and clinical examination. Recently, Magnetic Resonance Imaging (MRI) and Ultrasound have been proposed as the imaging modality to confirm the clinical diagnosis and in planning the surgical management of these tumours. However, these imaging modalities are not routinely available in rural setting and also are expensive. Read More

    Glomus faciale tumors: A report of 3 cases and literature review.
    Ear Nose Throat J 2017 Mar;96(3):E7-E12
    Department of Otolaryngology-Head and Neck Surgery, Loyola University Medical Center, 2160 S. First Ave., Maywood, IL 60153, USA.
    Our objectives in reporting this case series are to familiarize readers with the rare occurrence of paragangliomas originating along the facial nerve and to provide a literature review. We describe 3 such cases that occurred at our tertiary care academic medical center. Two women and 1 man presented with a tumor adjacent to the vertical segment of the facial nerve. Read More

    Intravenous Glomus Tumor Masquerading as Lateral Antebrachial Cutaneous Neuroma.
    Hand (N Y) 2017 Mar 22;12(2):NP19-NP21. Epub 2016 Oct 22.
    New York University, USA; Miami Children's Hospital, FL, USA.
    Background: Intravenous glomus tumors are extremely rare. Methods: We report a patient with an intravenous glomus tumor within a venous aneurysm misdiagnosed as a neuroma of the lateral antebrachial cutaneous nerve, based on clinical exam, electrodiagnostic studies, and findings on a magnetic resonance imaging neurogram. Results: After surgical resection, the patient's symptoms, including pain and localized hypersensitivity, totally resolved. Read More

    The Risk of Radiation-Induced Tumors or Malignant Transformation After Single-Fraction Intracranial Radiosurgery: Results Based on a 25-Year Experience.
    Int J Radiat Oncol Biol Phys 2017 Apr 9;97(5):919-923. Epub 2017 Jan 9.
    Department of Radiation Oncology, Mayo Clinic College of Medicine, Rochester, Minnesota.
    Purpose: To determine the risk of radiation-induced tumors or malignant transformation after single-fraction intracranial stereotactic radiosurgery (SRS).

    Methods And Materials: We performed a retrospective review of 1837 patients who received single-fraction SRS for arteriovenous malformation or benign tumor (meningioma, vestibular schwannoma, pituitary adenoma, glomus tumor) at a single center between 1990 and 2009. Patients were excluded if they refused research authorization (n=31), had a genetic predisposition to tumor development (n=84), received prior or concurrent radiation therapy (n=79), or had less than 5 years of imaging follow-up after SRS (n=501). Read More

    Glomangiomatosis of the sciatic nerve: a case report and review of the literature.
    Skeletal Radiol 2017 Jun 17;46(6):807-815. Epub 2017 Mar 17.
    Department of Orthopedic Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 1448, Houston, TX, 77030, USA.
    Glomus tumors are hamartomas, which tend to occur in sites rich in glomus bodies, such as the subungual regions of digits or the deep dermis of the palm, wrist, forearm, and foot. Very rarely, they may involve peripheral nerves. We describe a patient, who, following surgical resection of a solitary glomus tumor of the left distal sciatic nerve in his teens, had recurrence with development of multiple tumors in the course of the nerve over several years. Read More

    Glomus vagale tumour, can it be diagnosed only on sonography?
    J Ultrasound 2017 Mar 13;20(1):73-79. Epub 2017 Jan 13.
    Department of Pathology, University College of Medical Sciences (University of Delhi) and GTB Hospital, Dilshad Garden, Delhi, 110095 India.
    Vagal paragangliomas are rare benign tumors accounting for only 3% of head and neck paragangliomas and arise from vagal ganglions, predominately the nodose ganglion in the carotid sheath. Imaging plays an important role in their diagnosis, differentiation from more common lesions presenting in the carotid space, and management. MRI is the method of choice for investigation when paragangliomas are clinically suspected. Read More

    Malignant glomus tumors of the head and neck in children and adults: Evaluation and management.
    Laryngoscope 2017 Mar 14. Epub 2017 Mar 14.
    Department of Otolaryngology and Communication Enhancement, Boston Children's Hospital, Boston, Massachusetts, U.S.A.
    Objectives/hypothesis: To describe our current multidisciplinary approach to pediatric malignant glomus tumors of the head and neck and review the current literature.

    Study Design: Retrospective chart review at a tertiary referral children's hospital and a comprehensive literature review.

    Methods: A comprehensive literature search of PubMed, Embase, Web of Science, Google Scholar, and EBSCO with respect to malignant glomus tumors of the head and neck was conducted. Read More

    Pituitary Carcinoma in a Patient with an SDHB Mutation.
    Endocr Pathol 2017 Mar 10. Epub 2017 Mar 10.
    Centre of Endocrinology, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London, EC1M 6BQ, UK.
    We present the first case of pituitary carcinoma occurring in a patient with a succinate dehydrogenase subunit B (SDHB) mutation and history of paraganglioma. She was initially treated for a glomus tumour with external beam radiotherapy. Twenty-five years later, she was diagnosed with a non-functioning pituitary adenoma, having developed bitemporal hemianopia. Read More

    DIAGNOSIS OF ENDOCRINE DISEASE: Expanding the cause of hypopituitarism.
    Eur J Endocrinol 2017 Jun 3;176(6):R269-R282. Epub 2017 Mar 3.
    School of MedicineUniversity of Belgrade, Belgrade, Serbia
    Hypopituitarism is defined as one or more pituitary hormone deficits due to a lesion in the hypothalamic-pituitary region. By far, the most common cause of hypopituitarism associated with a sellar mass is a pituitary adenoma. A high index of suspicion is required for diagnosing hypopituitarism in several other conditions such as other massess in the sellar and parasellar region, brain damage caused by radiation and by traumatic brain injury, vascular lesions, infiltrative/immunological/inflammatory diseases (lymphocytic hypophysitis, sarcoidosis and hemochromatosis), infectious diseases and genetic disorders. Read More

    Overt and Subclinical Baroreflex Dysfunction After Bilateral Carotid Body Tumor Resection: Pathophysiology, Diagnosis, and Implications for Management.
    World Neurosurg 2017 May 27;101:559-567. Epub 2017 Feb 27.
    Department of Neurosurgery, Baylor College of Medicine, Houston, Texas, USA; Department of Neurosurgery, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, USA. Electronic address:
    Background: Carotid body paragangliomas are rare, usually benign, tumors arising from glomus cells of the carotid body. Bilateral involvement is present in ∼5% of sporadic cases and up to one third of familial cases. In most patients undergoing bilateral resection of carotid body tumors, a condition known as baroreflex failure syndrome (BFS) develops after resection of the second tumor characterized by headache, anxiety, emotional lability, orthostatic lightheadedness, hypertension, and tachycardia. Read More

    Glomangiosarcoma Arising from a Prior Biopsy Site.
    Plast Reconstr Surg Glob Open 2017 Jan 25;5(1):e1219. Epub 2017 Jan 25.
    Department of Surgery, New York Presbyterian-Brooklyn Methodist Hospital, Brooklyn, N.Y.; and The Combined Division of Plastic Surgery, New York-Presbyterian Hospital (Weill Cornell Medicine), New York, N.Y.
    Glomangiosarcoma represents a rare malignant variant of the benign glomus tumor that typically presents as a tender, slowly growing nodule with a predilection for the lower extremities. Unlike their benign counterparts, glomangiosarcomas may display aggressive characteristics such as large size, local invasion, and a tendency to recur after excision. Although wide local excision remains the treatment of choice, rare cases of systemic metastasis have been previously reported. Read More

    Unusual Volar Pulp Location of Glomus Tumor.
    Plast Reconstr Surg Glob Open 2017 Jan 30;5(1):e1215. Epub 2017 Jan 30.
    Departments of Plastic Surgery and Orthopedic Surgery, University of Pittsburgh, Pittsburgh, Pa.; and VA Pittsburgh Healthcare System, Pittsburgh, Pa.
    Glomus tumors are benign, painful growths originating from glomus bodies and comprise just 1% of tumors arising in the hand, with fewer than 10% in the volar pulp of digits. Hallmark symptoms of glomus tumors include hypersensitivity to cold, heightened pinprick sensitivity, and paroxysmal pain. We report a 72-year-old, right-hand dominant man who presented with pain in the left middle finger, localized to the tip. Read More

    Endoscopic Management of Middle Ear Paragangliomas: A Case Series.
    Otol Neurotol 2017 Mar;38(3):408-415
    *Department of Otolaryngology-Head and Neck Surgery, University of Texas Southwestern Medical Center, Dallas, Texas†Department of Otolaryngology-Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, Tennessee‡Department of Otolaryngology, Universidade Estadual do Ceará, Ceará, Brazil.
    Objective: To investigate the efficacy and safety of endoscopic middle ear paraganglioma (glomus tympanicum) resection.

    Study Design: Case series with chart review.

    Setting: Multi-institutional tertiary university medical centers. Read More

    Anterior Skull Base Glomangioma-Induced Osteomalacia.
    J Neurol Surg Rep 2017 Jan;78(1):e9-e11
    Department of Otolaryngology-Head and Neck Surgery, Baylor College of Medicine, Houston, Texas, United States.
    Oncogenic osteomalacia (OO) is an uncommon but treatable cause of osteomalacia related to tumor production of FGF23, usually caused by benign mesenchymal neoplasms. Paranasal sinus glomangiomas are a rare cause of OO, with only one previously reported case. Here we describe a second case (first reported in English) of paranasal sinus glomangioma-induced osteomalacia in a 42-year-old man. Read More

    Utility of an Ultrasonic Aspirator in Transcanal Endoscopic Resection of Temporal Bone Paraganglioma.
    J Neurol Surg B Skull Base 2017 Feb 26;78(1):96-98. Epub 2016 Jul 26.
    Department of Otolaryngology - Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, United States; Department of Neurosurgery, Vanderbilt University Medical Center, Nashville, Tennessee, United States.
    The objective of this study was to evaluate the role of removing middle ear paragangliomas using an ultrasonic aspirator (UA) through a transcanal, exclusively endoscopic approach. Three consecutive patients undergoing transcanal endoscopic resection of middle ear paragangliomas using an UA were retrospectively studied. The primary outcome measure was achieving gross total tumor resection. Read More

    Patients with benign hand tumors are indicated for surgery according to patient-rated outcome measures.
    J Plast Reconstr Aesthet Surg 2017 Apr 9;70(4):487-494. Epub 2017 Jan 9.
    Department of Hand Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan.
    Introduction: This study assessed the treatment outcomes of upper extremity benign tumors using the patient-rated outcome measures of Hand20 questionnaire.

    Methods: In total, 304 patients who underwent surgery for benign bone and soft tissue tumors of the upper limb were included. Tumors were classified into three size groups: <1 cm, 1-3 cm, and >3 cm. Read More

    Breast Cancer Metastasis on the Neck Mimicking a Glomus Tumor.
    J Craniofac Surg 2017 Jan 30. Epub 2017 Jan 30.
    *Department of Otorhinolaryngology, Head and Neck Surgery, Istanbul Medical Faculty, University of Istanbul †Department of Pathology, Istanbul Medical Faculty, University of Istanbul, Istanbul, Turkey.
    Cervical metastases from breast carcinoma are extremely rare after several years of disease-free survival. In this article, a metastatic tumor of the neck originating from a breast carcinoma, which has been treated 14 years ago, is discussed. A case is presented of a 48-year-old female patient with a history of breast carcinoma, which was surgically treated approximately 14 years ago. Read More

    Glomus Tumor of the Stomach - A Case Report and A Literature Review.
    Pol Przegl Chir 2016 Dec;88(6):356-358
    The study presented a case of a patient with a glomus tumor of the stomach, a mesenchymal neoplasm manifesting with upper gastrointestinal bleeding (Forrest IB). The patient was operated twice. First, he underwent elective laparotomy, during which Billroth I (Rydygier's method) gastric resection was performed. Read More

    Thoracoscopic Surgery for Glomus Tumor: An Uncommon Mediastinal Neoplasm and Iatrogenic Tracheal Rupture.
    Case Rep Surg 2017 4;2017:3621839. Epub 2017 Jan 4.
    Department of Pathology, Taizhou Hospital, Wenzhou Medical University, Linhai, Zhejiang, China.
    Mediastinal glomus tumors are rarely recognized, and only seven cases have been reported in the literature. Here, we describe a rare mediastinal glomus tumor and review the characteristics of this rare clinical case. The patient was a 50-year-old female who presented with coughing for 3 months. Read More

    Stereotactic Radiosurgical Treatment of Glomus Jugulare Tumors.
    Otol Neurotol 2017 Apr;38(4):555-562
    *Department of Otolaryngology †Charlotte Eye, Ear, Nose, and Throat Associates, Charlotte, North Carolina ‡Department of Radiation Oncology §Department of Neurosurgery, Wake Forest University Baptist Medical Center, Winston-Salem, North Carolina.
    Objective: Determine treatment outcomes of stereotactic radiosurgery (SRS) for glomus jugulare tumors (GJT), focusing on three-dimensional volume change and symptoms before and after SRS, as well as complications related to SRS.

    Study Design: Retrospective case review.

    Setting: Tertiary referral center. Read More

    A rare case of Glomus Tumor of the Thenar Eminence of the Hand Misdiagnosed as Carpal Tunnel Syndrome.
    J Orthop Case Rep 2016 Jul-Aug;6(3):43-45
    Department of Dermatology, JSS Hopsital & University. Mysore, India.
    Introduction: Glomus body is an apparatus present in the skin at the arterio-venous junction whose main function is to control the body temperature. Hyperplasia of the glomus body results in an entity called glomus tumor. Masson described this entity first in 1924, as a tumor of the neuromyoarterial body. Read More

    Glomus Tumor - A Rarity; M.R.I- A big help in early Diagnosis.
    J Orthop Case Rep 2016 Jul-Aug;6(3):38-39
    Department of Radiology, S.G.R.D Medical college, Amritsar, India.
    Introduction: Glomus tumor is a rare benign tumor arising from neuroarterial plexus concentrated beneath the nailbed usually in women of age group 20-40 yrs. The plexus is an arteriovenous anastomosis functioning without intermediary capillary bed, we report a case of glomus tumor affecting the nailbed of left little finger with characteristic periodic, spontaneous excruciating pain and temperature related algesia for the last 6 months. MRI helped in clinching the diagnosis at an early stage. Read More

    Symplastic glomus tumor of the urinary bladder treated by robot-assisted partial cystectomy: a case report and literature review.
    Urologia 2017 Jan 16. Epub 2017 Jan 16.
    Department of Urology, IRCCS Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan - Italy.
    Glomus tumors arising in the urinary bladder are extremely rare, and only two cases have been reported in the English Literature. We present a case of a 58-year-old man with an asymptomatic mass of the anterior wall of the bladder that measured 2.5 × 2. Read More

    Phenotypic characterization of perivascular myoid cell neoplasms, using myosin 1B, a newly identified human pericyte marker.
    Hum Pathol 2017 Apr 11;62:187-198. Epub 2017 Jan 11.
    Department of Regenerative and Infectious Pathology, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka 431-3192, Japan. Electronic address:
    Our aims were to identify pericyte-specific markers for the analysis of formalin-fixed, paraffin-embedded human tissue samples, and to characterize perivascular myoid cell neoplasms phenotypically. Previously identified pericyte markers failed to distinguish pericytes from other cellular types, such as vascular smooth muscle cells (vSMCs) and fibroblasts, in immunohistochemistry analysis. However, we compared gene expression profiles between pericytes, vSMCs, and fibroblasts, and performed human skin vasculature immunohistochemistry analysis, which led to the identification of myosin 1B (MYO1B) as a novel pericyte marker. Read More

    Anesthetic approaches in carotid body tumor surgery.
    North Clin Istanb 2016 21;3(2):97-103. Epub 2016 Nov 21.
    Department of Anesthesiology and Reanimation, Antalya Training and Research Hospital, Antalya, Turkey.
    Objective: Carotid body tumors (CBT) are benign tumors that originate from neural non-chromaffin cells that are typically localized near carotid bifurcation. Surgical removal of the tumor is the most appropriate treatment. General anesthesia is preferred anesthetic technique for CBT surgery. Read More

    Glomus tumors of the fingers: Expression of vascular endothelial growth factor.
    World J Orthop 2016 Dec 18;7(12):843-846. Epub 2016 Dec 18.
    Sittisak Honsawek, Pravit Kitidumrongsook, Pobe Luangjarmekorn, Kawee Pataradool, Adisorn Patradul, Vinai Parkpian Orthopaedic Research Center, Department of Orthopaedics, Faculty of Medicine, Chulalongkorn University, King Chulalongkorn Memorial Hospital, Thai Red Cross SocietyBangkok 10330, Thailand.
    Glomus tumors are uncommon, benign, small neurovascular neoplasms derived from glomus bodies in the reticular dermis. Glomus bodies are found throughout the body to regulate body temperature and skin circulation; however, they are concentrated in the fingers and the sole of the foot. The typical presentation is a solitary nodule in the subungual or periungual area of the distal phalanx. Read More

    A reddish pulsatile mass beyond tympanic membrane: think before act.
    Eur Rev Med Pharmacol Sci 2016 Dec;20(23):4837-4839
    Unit of Otolaryngology, University Campus Bio-Medico, Rome, Italy.
    We report a case of a 76-year-old man that referred to our hospital because of progressive mixed right hearing loss, aural fullness and pulsatile tinnitus synchronized with heart beats. Otoscopic examination revealed a reddish pulsatile mass beyond tympanic membrane. CT and MRI scans showed a class C glomus tumor. Read More

    Ang-2 but not Ang-1 expression in perivascular soft tissue tumors.
    J Orthop 2017 Mar 28;14(1):147-153. Epub 2016 Nov 28.
    School of Dentistry, University of California, Los Angeles, Los Angeles, CA 90095, USA; Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA; Orthopedic Hospital Research Center, University of California, Los Angeles, Los Angeles, CA 90095, USA; Department of Pathology, Johns Hopkins University, Baltimore, MD 21279, USA.
    Perivascular soft tissue tumors are relatively uncommon neoplasms of unclear line of differentiation, although most are presumed to originate from pericytes. Previously, we reported a shared immunophenotype across these related tumor types. Here, we extend these findings to examine the expression of the pericyte markers angiopoietin-1 and -2 (Ang-1 and -2) among perivascular soft tissue tumors. Read More

    A blue middle ear mass: Cholesterol granuloma mimicking a glomus tumor and endolymphatic sac tumor.
    Am J Otolaryngol 2017 Jan - Feb;38(1):100-102. Epub 2016 Sep 28.
    Otolaryngology-Head and Neck Surgery, Eastern Virginia Medical School, 600 Gresham Drive Suite 1100, VA, Norfolk, VA, United States.
    Cholesterol granuloma (CG) is the most common benign lesion of the petrous apex, however, it can grow significantly large and become destructive causing a diagnostic dilemma. This case presents a 25-year-old female with 2-year history of left-sided progressive and profound hearing loss, a transient left-sided facial paralysis and cranial nerve 10 palsy who presented with a blue middle ear mass. Her diagnosis did not become apparent until direct visualization intraoperatively. Read More

    Long Distance Endovascular Growth of Jugulotympanic Paraganglioma Evident in 68Ga-DOTATATE PET but Concealed on CT.
    Clin Nucl Med 2017 Feb;42(2):135-137
    From the Departments of *Nuclear Medicine, †Clinical Radiology-Neuroradiology, and ‡Otorhinolaryngology, Head and Neck Surgery, University Hospital Münster, Münster, Germany.
    A 60-year-old woman was referred to contrast-enhanced CT for evaluation of jugular vein thrombosis incidentally detected by ultrasound. Contrast-enhanced CT showed an enhanced tumor of the right skull base highly suspicious of jugulotympanic paraganglioma. However, the jugular veins showed a nearly symmetric contrast enhancement without clear evidence of thrombosis. Read More

    Color Doppler Sonography of Extradigital Glomus Tumors.
    J Ultrasound Med 2017 Jan 3;36(1):231-238. Epub 2016 Dec 3.
    Departments of Radiology and Dermatology, Institute for Diagnostic Imaging and Research of the Skin and Soft Tissues Clinica Servet, University of Chile, Santiago, Chile.
    We retrospectively collected cases of surgically proven extradigital glomus tumor (EDGT) and reviewed their demographic, clinical, and sonography features. A total of 18 single, subcutaneous EDGTs were gathered. All but one were located in the extremities. Read More

    Gastric glomus tumor.
    J Surg Case Rep 2016 Nov 24;2016(11). Epub 2016 Nov 24.
    Crittenton Hospital Medical Center, Rochester Hills, MI 48307, USA.
    Gastric glomus tumors are rare, mesenchymal neoplasms, generally described as benign and account for nearly 1% of all gastrointestinal soft tissue tumors. The most common gastrointestinal site of involvement is the stomach, particularly the antrum. Gastric glomus tumors are submucosal tumors that lack specific clinical and endoscopic characteristics, and are often mistaken for the more common gastrointestinal stromal tumors. Read More

    Unusual Glomus Tumor of the Penis.
    Curr Urol 2016 Oct 20;9(3):113-118. Epub 2016 Sep 20.
    Department of Physiology and Biophysics, SUNY at Stony Brook, New York, USA; Department of Urology, SUNY at Stony Brook, New York, USA.
    Introduction: Glomus tumors are benign neoplasms commonly found in subungual regions of the extremities and rarely located in the penis. Misdiagnosis of glomus tumors is common; therefore, symptoms and clinical presentations should be reviewed.

    Objective: The primary objective of this review article is to emphasize the pathogenesis, pathology, clinical presentation, symptoms, diagnosis, and treatment methods of glomus tumors in order to better identify and manage the condition. Read More

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