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    [Gastric glomus tumors expressing synaptophysin: clinicopathologic and immunohistochemical analyses].
    Zhonghua Bing Li Xue Za Zhi 2017 Nov;46(11):756-759
    Department of Pathology, Taizhou Hospital, Wenzhou Medical University, Taizhou 317000, China.
    Objective: To investigate the clincopathologic and immunohistochemical features of gastric glomus tumors and their differences from gastric neuroendocrine neoplasms. Methods: Six cases of gastric glomus tumors, 8 cases of glomus tumors in other sites and 7 cases of gastric neuroendocrine neoplasms were collected from the Department of Pathology, Taizhou Hospital. The clinicopathological and immunohistochemical characteristics of these tumors were analyzed retrospectively. Read More

    Glomangiomyoma of the neck in a child in Nepal: a rare case report and literature review.
    BMC Ear Nose Throat Disord 2017 2;17. Epub 2017 Nov 2.
    Department of ENT - Head and Neck Studies, Universal College of Medical Sciences, Tribhuvan University Teaching Hospital, Bhairahawa, Nepal.
    Background: Glomangiomyoma is a rare histological variant of glomus tumour. Clinically, it mimicks as a haemangioma and is challenging to diagnose. Its occurrence in the neck of a child has not been previously described. Read More

    Acquired Vascular Tumors of the Head and Neck.
    Otolaryngol Clin North Am 2017 Oct 26. Epub 2017 Oct 26.
    Department of Otolaryngology-Head and Neck Surgery, NYU School of Medicine, New York, NY, USA. Electronic address:
    Vascular neoplasms of the head and neck present with a wide spectrum of signs and symptoms. Diagnosis requires a high index of suspicion and is usually made after tumors are large enough to be visually apparent or cause symptoms. This article discusses the most common acquired benign and malignant vascular tumors, with an emphasis on their evaluation and treatment. Read More

    Successful Resection of locally infiltrative Glomus Tumor without pulmonary resection.
    Int J Surg Case Rep 2017 Sep 23;41:191-193. Epub 2017 Sep 23.
    Departments of Surgery, Nagasaki University Graduate School of Biological Sciences, Japan. Electronic address:
    Introduction: Extracutaneous glomus tumors occurring in the bronchus is very rare. Complete resection is basic procedure for treatment of glomus tumor. We present a glomus tumor of the left main bronchus that was successfully treated with rigid bronchoscopy followed by sleeve resection of the left main bronchus. Read More

    Atypically localized glomus tumor causing anterior interosseous nerve syndrome: A case report.
    Acta Orthop Traumatol Turc 2017 Oct 19. Epub 2017 Oct 19.
    Metin Sabanci Baltalimani Bone Diseases Training and Research Hospital, Istanbul, Turkey.
    This article presents a 48-year-old male patient who presented with pain in the left forearm and weakness and clumsiness in the left hand of 6 months' duration. Flexor motor strength loss of the thumb and the index finger was present and neurophysiologic tests showed findings compatible with axonal injury in the anterior interosseous nerve (AIN) innervated muscles. Magnetic resonance imaging revealed a space-occupying lesion in the proximal forearm resembling a glomus tumor. Read More

    Multiple glomus tumours in multidigit nail bed.
    Handchir Mikrochir Plast Chir 2017 Oct 17;49(5):321-325. Epub 2017 Oct 17.
    Bundang CHA Medical Center, Department of Orthopaedic Surgery.
    Glomus tumours are lesions of the glomus body. A solitary glomus tumour is a more common, characteristically painful lesion, frequently located under the nail, whereas multiple glomus tumours are a rare clinical and genetic entity. Multiple glomus tumours are rarely subungual and do not show preference for any particular region of the body. Read More

    A gastric glomus tumor resected using non-exposed endoscopic wall-inversion surgery.
    Clin J Gastroenterol 2017 Oct 16. Epub 2017 Oct 16.
    Departments of Gastroenterology, Aichi Medical University School of Medicine, 1-1 Yazakokarimata, Nagakute, Aichi, 480-1195, Japan.
    Gastric glomus tumors are extremely rare, constituting approximately 1% of gastric mesenchymal tumors. We report the case of a 45-year-old female patient in whom upper gastrointestinal endoscopy revealed a 3-cm submucosal tumor with a bridging fold in the posterior wall of the antrum of the stomach. Contrast-enhanced computed tomography revealed the tumor to be hypervascular in the arterial phase and exhibit continuous enhancement in the post-venous phase. Read More

    Glomus Tumor of the Sciatic Nerve: An Extraspinal Cause of Sciatica.
    Orthopedics 2017 Sep 21:1-3. Epub 2017 Sep 21.
    Glomus tumors are small, benign tumors that arise from glomus bodies, structures found normally within the dermis that assist in temperature regulation via their vasoconstrictive response to sympathetic stimuli. Glomus tumors are found typically in the hand and are classically a cause of focal pain and temperature sensitivity. They often present as a small blue lesion seen under the nail bed of a finger or a toe and cause point tenderness. Read More

    Extradigital glomic tumor of the forearm. About a case and review of literature.
    Ann Chir Plast Esthet 2017 Sep 15. Epub 2017 Sep 15.
    Service de chirurgie plastique et reconstructrice, centre des brûlés, hôpital Hôtel-Dieu, CHU de Nantes, place Alexis-Ricordeau, 44093 Nantes cedex 01, France. Electronic address:
    We report the clinical case of a 72-year-old man followed for 10years by a specialized pain center, for neuropathic pain poorly systematized, triggered by the contact of the anteromedial face of the right forearm. After surgical excision, histological analysis indicated a well-circumscribed nodule in the subcutaneous region, confirming that the mass was a glomus tumor. In this clinical case, surgical excision allowed an immediate disappearance of the pains without recurrence to this day. Read More

    [Primary tracheal malignant glomus tumor with lung metastasis diagnosed by pathological analysis: a case report and literature review].
    Zhonghua Jie He He Hu Xi Za Zhi 2017 Sep;49(9):697-702
    Department of Respiratory Medicine, Affiliated Shantou Hospital of Sun Yat-sen University, Shantou 515000, China.
    Objective: To study the clinical manifestations, pathological features, diagnosis, differential diagnosis, treatment and prognosis of primary tracheobronchial or pulmonary malignant glomus tumor (MGT). Methods: A case of primary tracheal MGT with lung metastasis diagnosed by pathological analysis admitted to Affiliated Shantou Hospital of Sun Yat-sen University in May. 2015 was analyzed, and the related literatures were reviewed. Read More

    An Extradigital Glomus Tumor of the Median Antebrachial Vein.
    J Hand Surg Am 2017 Sep 6. Epub 2017 Sep 6.
    Department of Plastic Surgery, Cleveland Clinic Florida, Weston, FL.
    Glomus tumors are benign vascular neoplasms that arise from specialized dermal arteriovenous anastomoses called glomus bodies. These tumors are most often found in the digital pulp and subungual region of the fingertips; however, a review of the literature suggests that extradigital glomus tumors may occur more often than is generally recognized. Although most extradigital glomus tumors arise within subcutaneous tissues, glomus tumors have occasionally been found within bones, nerves, and blood vessels. Read More

    Primary Intracranial Extraskeletal Mesenchymal Chondrosarcoma: Clinical Mimicry as Glomus Jugulare.
    Ann Neurosci 2017 Jul 24;24(3):181-186. Epub 2017 Jul 24.
    Department of Neurosurgery, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
    Background: Extraskeletal mesenchymal chondrosarcoma (ESMCS) is an unusual pathologic variant of chondrosarcoma. There are no specific clinicoradiographic parameters to distinguish it from other intracranial pathologies. The diagnosis can be established only on the basis of histopathology, which may pose significant challenges in certain unusual locations. Read More

    BRAF V600E Mutations Occur in a Subset of Glomus Tumors, and Are Associated With Malignant Histologic Characteristics.
    Am J Surg Pathol 2017 Nov;41(11):1532-1541
    *Mayo Clinic, Rochester, MN †St Jude Children's Research Hospital, Memphis, TN ‡Johns Hopkins Hospital, Baltimore, MD.
    Glomus tumors are rare mesenchymal neoplasms with a phenotype akin to the modified smooth muscle cells of the glomus body. Most are benign, but rare examples show malignant histologic characteristics and aggressive behavior. We recently encountered a malignant glomus tumor with BRAF V600E mutation. Read More

    Glomus Tumor of the Neck Detected With 99mTc EDDA HYNIC-TOC.
    Clin Nucl Med 2017 Oct;42(10):758-760
    From the *Clinical Department of Nuclear Medicine, and †Clinical Department of Radiology, Clinical Hospital Centre Rijeka, Krešimirova 42, Rijeka, Croatia.
    A 54-year-old woman was referred to thyroid evaluation because of a lump on the left side of the neck. Ultrasound exam did not show any thyroid abnormality, but highly perfused nodule at the left common carotid artery bifurcation was found. Because of the specific location, somatostatin receptor scintigraphy with Tc EDDA HYNIC-TOC was performed, starting with perfusion images and followed with SPECT/CT imaging at 2 and 4 hours. Read More

    Nonintubated Spontaneous Respiration Anesthesia for Tracheal Glomus Tumor.
    Ann Thorac Surg 2017 Aug;104(2):e161-e163
    Department of Thoracic Surgery, The First Affiliated Hospital of Guangzhou Medical University, Guangdong, China; Guangzhou Research Institute of Respiratory Disease, China Key Laboratory of Respiratory Disease, Guangdong, China; National Center for Clinical Trials on Respiratory Diseases, Guangdong, China. Electronic address:
    Previous tracheal surgeries were performed under tracheal and cross-field intubation. However, the intubation would lead to bleeding if the tumors were large or hemorrhagic. Moreover, the tracheal intubation might interfere the surgical vision and anastomosis during the reconstruction process. Read More

    Percutaneous Trans-Tracheal Endoscopic Approach: A Novel Technique for the Excision of Benign Lesions of Thoracic Trachea.
    J Laparoendosc Adv Surg Tech A 2017 Jul 19. Epub 2017 Jul 19.
    Department of Otorhinolaryngology and Head and Neck Surgery, All India Institute of Medical Sciences , New Delhi, India .
    Introduction: Currently, neoplasms of the trachea and lower airway demand open transcervical approach with or without thoracotomy. We describe here a novel, minimally invasive approach for an intraluminal lesion of the thoracic trachea, called percutaneous trans-tracheal endoscopic approach (PTEA). Apart from obvious advantages over potentially morbid open procedures, this technique has certain peculiar benefits over rigid or flexible bronchoscopic approach. Read More

    Glomangioma of the Kidney: A Rare Case of Glomus Tumor and Review of the Literature.
    Case Rep Pathol 2017 18;2017:7423642. Epub 2017 Jun 18.
    Department of Pathology, King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia.
    Background: Glomus tumors are rare mesenchymal tumors originating from glomus bodies in the skin. Glomus tumors of the kidney are rare tumors and only a few cases have been reported in the medical literature. An extensive search revealed a very limited number of primary renal glomus tumors. Read More

    Functional Ulnar Nerve Paraganglioma: First Documented Occurrence in the Extremity With Hitherto Undescribed Associated Extensive Glomus Cell Hyperplasia and Tumorlet Formation.
    Int J Surg Pathol 2017 Jul 1:1066896917720750. Epub 2017 Jul 1.
    2 Prince of Wales Hospital, New Territory, Hong Kong.
    Extra-adrenal paraganglioma has never been described in the extremities. A 34-year-old woman complained of an enlarging mass in the right forearm for 18 months. Imaging showed a circumscribed vascular tumor attached to the ulnar nerve; biopsy revealed features of paraganglioma. Read More

    Endovascular Approach to Glomus Jugulare Tumors.
    Pol J Radiol 2017 19;82:322-326. Epub 2017 Jun 19.
    Department of Neurosurgery, Medical University of Silesia, School of Medicine in Katowice, Katowice, Poland.
    Background: Paragangliomas are benign neuroendocrine tumors derived from the glomus cells of the vegetative nervous system. Typically, they are located in the region of the jugular bulb and middle ear. The optimal management is controversial and can include surgical excision, stereotactic radiosurgery and embolization. Read More

    Glomus Tumor of the Larynx: A Rare Synchronous Paraganglioma in a Patient with Bilateral Carotid Body Tumor Detected on (68)Ga-DOTANOC PET/CT.
    Indian J Nucl Med 2017 Jul-Sep;32(3):241-242
    Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India.
    Paragangliomas are neoplasms arising from extra-adrenal chromaffin tissue. They frequently cause symptoms by overproduction of catecholamines with known predilection to multicentricity. We describe the case of a patient with bilateral carotid body tumor who underwent a baseline 68 Gallium labeled [1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid]-1-NaI3-Octreotide. Read More

    Mandibular Lytic Lesion in Familial Paraganglioma Syndrome Type I: A Clinical Conundrum.
    Ann Otol Rhinol Laryngol 2017 Aug 1;126(8):615-618. Epub 2017 Jul 1.
    3 Department of Head and Neck Surgery, Florida Hospital Celebration Health, Celebration, Florida, USA.
    Objective: The entity of primary mandibular paraganglioma (PGL) is not well accepted within the head and neck. Mandibular PGLs hitherto reported in literature are malignant metastatic lesions, mostly from a pheochromocytoma.

    Methods: We report a case of mandibular lytic lesion in a young female with multifocal PGLs but no family history of PGLs. Read More

    Bilateral Solitary Glomus Tumour of Thumb: A Case Report.
    J Clin Diagn Res 2017 May 1;11(5):RD04-RD06. Epub 2017 May 1.
    Registrar, Department of Orthopaedics, Sunshine Hospital, Secunderabad, Andhra Pradesh, India.
    Glomus tumours are benign neoplastic lesions of glomus body, a thermoregulatory apparatus of cutaneous microvasculature. These tumours can arise at any location of the body but most commonly seen in subungual region of fingers. Bilateral solitary glomus tumour of hand is a rare entity. Read More

    Gastric Glomus Tumour Misdiagnosed as Gastric Carcinoid: An Unfamiliar Entity with Aids to Diagnosis and Review of Literature.
    J Clin Diagn Res 2017 May 1;11(5):ED32-ED33. Epub 2017 May 1.
    Professor, Department of Nephrology, Christian Medical College and Hospital, Vellore, Tamil Nadu, India.
    Glomus tumour (GT) is a rare mesenchymal tumour of the stomach with Gastrointestinal Stromal Tumour (GIST), leiomyoma and schwannoma being far more common and comprising more than 90% of all gastric mesenchymal tumours. As glomus bodies are located in the peripheral parts of the human body, these tumours are peripherally located, classically the subungual region, hands, feet and trunk. While being evaluated for renal problems, a middle aged lady was incidentally found to have a gastric tumour. Read More

    Glomangiomatosis: a case report.
    Skeletal Radiol 2017 Jun 27. Epub 2017 Jun 27.
    Department of Radiology, Rutgers, the State University of New Jersey-New Jersey Medical School, Newark, NJ, USA.
    Glomangiomatosis is a benign vascular variant of a glomus tumor. The lesion represents only 5% of glomus tumors with unusual or atypical features and even fewer glomus tumors with typical features. The lesions are most commonly located in the distal extremities and are multiple, deep, extensive, and often pain producing. Read More

    Glomus Tumor of the Toe.
    J Am Podiatr Med Assoc 2017 May;107(3):257-260
    A glomus tumor is an uncommon, predominantly benign, neoplastic lesion that primarily involves a thermoregulatory microvascular apparatus, the glomus body. Although these lesions can occur anywhere in the body, the subungual tissue of the hand represents the most common presentation site. Glomus tumors are not often encountered in the foot. Read More

    Glomus Tumor in the Tarsal Tunnel: A Case Report.
    J Foot Ankle Surg 2017 Jul - Aug;56(4):865-867
    Professor, Department of Orthopaedic Surgery, Nara Medical University, Nara, Japan.
    Glomus tumors are painful benign neoplasms. They commonly present in the hand and are mostly solitary lesions. We report a rare case of multiple glomus tumors in the lower leg. Read More

    Transducing-Like Enhancer of Split 1: A Potential Immunohistochemical Marker for Glomus Tumor.
    Am J Dermatopathol 2017 Jul;39(7):524-527
    *Pathology Department, Dr. Abdurrahman Yurtaslan Onkoloji Education and Research Hospital, Ankara, Turkey; and †Department of Pathology, Numune Education and Research Hospital, Ankara, Turkey.
    Glomus tumors (GTs) are rare, perivascular soft tissue tumors. Although GTs are usually found in the subcutaneous tissue, they may be detected in extracutaneous sites and mucosal areas. Transducing-like enhancer of split 1 (TLE1) is a highly useful immunohistochemical marker, which basically helps in differential diagnosis of synovial sarcoma. Read More

    Metastatic Renal Cell Carcinoma Masquerading as Jugular Foramen Paraganglioma: A Role for Novel Magnetic Resonance Imaging.
    Ann Otol Rhinol Laryngol 2017 Aug 10;126(8):606-610. Epub 2017 Jun 10.
    1 Division of Otolaryngology-Head and Neck Surgery, Department of Surgery, University of Utah, Salt Lake City, Utah, USA.
    Objectives: To describe a case of metastatic renal cell carcinoma (RCC) masquerading as a jugular foramen paraganglioma (JP). To compare imaging findings between skull base metastatic RCC and histologically proven paraganglioma.

    Methods: A case of unexpected metastatic skull base RCC is reviewed. Read More

    Glomangiomyoma of the Vagina: A Report of 2 Cases and Literature Review.
    Int J Gynecol Pathol 2017 Jul;36(4):334-338
    Department of Histopathology (S.R.), Queen Alexandra Hospital, Cosham, PortsmouthPan-Birmingham Gynaecological Cancer Centre (J.B.), City HospitalDepartment of Cellular Pathology (L.H.), Birmingham Women's NHS Trust, Birmingham, UKHistopathology Division (C.M.), Ospedale San Carlo Di Nancy, Rome, Italy.
    We report 2 cases of vaginal glomangiomyoma in a 53-year-old who presented with a painful vaginal mass, and a 56-year-old who had postmenopausal bleeding and in whom an incidental vaginal mass was identified and resected at the time of hysterectomy. Histologic examination of the resected masses showed solid, circumscribed, benign, smooth muscle-predominant tumors with interspersed small islands of epithelioid glomus cells. The glomus cells were intimately related to small-caliber blood vessels and showed no cytologic atypia or mitotic activity. Read More

    Comparative Neurologic Outcomes of Salvage and Definitive Gamma Knife Radiosurgery for Glomus Jugulare: A 20-Year Experience.
    J Neurol Surg B Skull Base 2017 Jun 23;78(3):251-255. Epub 2017 Jan 23.
    Department of Radiation Oncology, University of Tennessee Health Science Center, Memphis, Tennessee, United States.
    Objective  This case series investigates management of glomus jugulare (GJ) tumors utilizing definitive and salvage Gamma Knife stereotactic radiosurgery (GKSRS). Methods  A retrospective chart review was performed to collect data. Statistical analysis included patient, tumor, and treatment information. Read More

    Utility and tolerability of the long-pulsed 1064-nm neodymium:yttrium-aluminum-garnet (LP Nd:YAG) laser for treatment of symptomatic or disfiguring vascular malformations in children and adolescents.
    J Am Acad Dermatol 2017 Sep 1;77(3):473-479. Epub 2017 Jun 1.
    Department of Dermatology, University of California, San Francisco, California. Electronic address:
    Background: Vascular malformations manifest with pain, bleeding, disability, and disfigurement in a subset of children. There are scant data available on the utility and tolerability of laser surgery for symptomatic or disfiguring non-port-wine stain vascular malformations in children.

    Objective: The objective of this study was to determine the utility and tolerability of the 1064-nm long-pulsed neodymium:yttrium-aluminum-garnet (LP Nd:YAG) laser for treatment of symptomatic or disfiguring vascular malformations in children. Read More

    Tumors Presenting as Multiple Cranial Nerve Palsies.
    Case Rep Neurol 2017 Jan-Apr;9(1):54-61. Epub 2017 Apr 3.
    Department of Medicine, Bronx Lebanon Hospital Center, Bronx, NY, USA.
    Cranial nerve palsy could be one of the presenting features of underlying benign or malignant tumors of the head and neck. The tumor can involve the cranial nerves by local compression, direct infiltration or by paraneoplastic process. Cranial nerve involvement depends on the anatomical course of the cranial nerve and the site of the tumor. Read More

    Glomus tumors of the upper limb: Single-center retrospective study of clinical and functional outcomes.
    Hand Surg Rehabil 2017 Sep 23;36(4):290-295. Epub 2017 May 23.
    Department of Reconstructive and Plastic Surgery, University Hospital Nice, Pasteur 2, 30, avenue de la Voie-Romaine, 06000 Nice, France.
    Glomus tumors are rare and benign hamartomas, arising from neuro-myo-arterial proliferation and deriving from mesenchymal origin. As they have a long-term impact on the individual's quality of life, the primary complaint is unbearable pain. The aim of this study was to assess the clinical and functional outcomes of their surgical treatment, and to review their clinical, radiological and therapeutic features. Read More

    Robotic radiosurgery of head and neck paragangliomas: a single institution experience.
    Asia Pac J Clin Oncol 2017 May 24. Epub 2017 May 24.
    Department of Radiation Oncology, Acibadem University, Istanbul, Turkey.
    Aim: CyberKnife(®) is a robotic stereotactic radiotherapy system. The aim of this study is to evaluate the effectiveness and the safety of CyberKnife(®) on treating head and neck paragangliomas and to report our results.

    Methods: Between March 2009 and June 2014, 12 patients with head and neck paragangliomas have been referred to our clinic: in three cases had jugular paragangliomas, five cases had carotid body paragangliomas and three cases had tympanic paragangliomas. Read More

    Dumbbell-Shaped Jugular Foramen Tumors Extending to the Neck: Surgical Considerations Based on Imaging Findings.
    World Neurosurg 2017 Aug 9;104:14-23. Epub 2017 May 9.
    Department of Neurosurgery, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
    Objective: Dumbbell-shaped jugular foramen tumors (DSJFTs) extending to the neck present diagnostic and management difficulties because of their rarity, various pathologies, and multidisciplinary involvement. Accurate imaging findings are of great importance for surgical planning and clinical outcomes. However, few articles have discussed this issue to date. Read More

    Characteristics and prognosis of glomangiopericytomas: A systematic review.
    Head Neck 2017 Sep 12;39(9):1897-1909. Epub 2017 May 12.
    Department of Pathology, Incheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Incheon, Republic of Korea.
    Background: Glomangiopericytoma belongs to the category of borderline/low-malignant-potential tumors of the sinonasal tract, but no studies about prognosis have been reported.

    Methods: To define the characteristics of glomangiopericytoma and to identify its prognostic factors, a systematic review was performed. A total of 337 cases of glomangiopericytomas were analyzed. Read More

    Brace yourself: an unusual case of knee pain, an extradigital glomangioma of the knee.
    Radiol Case Rep 2017 Jun 8;12(2):357-360. Epub 2017 Apr 8.
    Department of Pathology, University of Florida College of Medicine-Jacksonville, Jacksonville, FL 32209, USA.
    The differential diagnosis for knee pain is extensive. Glomus tumors comprise approximately 1.6% of soft-tissue tumors in the extremities. Read More

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