4,454 results match your criteria Glomus Tumor

Renin Production by Juxtaglomerular Cell Tumors and Clear Cell Renal Cell Carcinoma and the Role of Angiotensin Signaling Inhibitors.

Mayo Clin Proc 2022 Jun 23. Epub 2022 Jun 23.

Department of Urology, Mayo Clinic, Rochester, MN. Electronic address:

Objective: To profile juxtaglomerular cell tumors (JXG) and histologic mimics by analyzing renin expression; to identify non-JXG renin-producing tumors in The Cancer Genome Atlas (TCGA) data sets; and to define the prevalence of hypertension (HTN) and patient outcomes with angiotensin signaling inhibitor (ASI) use in tumors of interest.

Patients And Methods: Thirteen JXGs and 10 glomus tumors (GTs), a histologic mimic, were evaluated for clinicopathologic features; TCGA data were analyzed to identify non-JXG renin-overexpressing tumors. An institutional registry was queried to determine the incidence of HTN, the use of ASIs in hypertensive patients, and the impact of ASIs on outcomes including progression-free survival (PFS) in a tumor type with high renin expression (clear cell renal cell carcinoma [CC-RCC] diagnosed between January 1, 2005, and December 31, 2012). Read More

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Glomus tumor of the stomach: a systematic review and illustrative case report.

Dig Dis 2022 Jun 26. Epub 2022 Jun 26.

Introduction Glomus tumor is a rare mesenchymal neoplasm that can be found anywhere throughout the body, includ-ing the stomach. Our goal was to present a case and a systematic review of the literature, reporting clinical, radiological, surgical, and pathological features of the disease. Methods We reviewed Pubmed and SCOPUS for all case reports and case series published after 2000. Read More

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Tracheal Glomus Tumor: A Case Report with CT Imaging Features.

Medicina (Kaunas) 2022 Jun 13;58(6). Epub 2022 Jun 13.

Department of Radiology, Biomedical Research Institute, Pusan National University Hospital, Pusan National University School of Medicine, Busan 49241, Korea.

Background And Objectives: Glomus tumors are rare benign tumors. The majority of them affect the skin the most and are rarer in the trachea, where the glomus bodies may not be present. Only scarce reports of tracheal glomus tumors have been reported solely with case reports of relevant articles. Read More

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causing vascular malformations: the clinical and genetic differentiation of cutaneous venous malformations.

BMJ Case Rep 2022 Jun 22;15(6). Epub 2022 Jun 22.

Oncology & Metabolism, University of Sheffield, Sheffield, Sheffield, UK

Cutaneous venous malformations frequently present with blue-pink lesions on the skin or mucosal surfaces. They can be problematic for patients who experience pain or unsightly lesions and can also be associated with significant bleeding. A proportion of venous malformations have been noted to occur in families, in particular glomuvenous malformations (GVMs). Read More

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Risk Factors Associated With Misdiagnosis of Digital Glomus Tumor: A Retrospective Cohort Study.

Ann Plast Surg 2022 Jun 11. Epub 2022 Jun 11.

Department of Orthopedics (Division of Hand Surgery), The Second Affiliated Hospital and Yuying Children' Hospital of Wenzhou Medical University, Key Laboratory of Orthopedics of Zhejiang Province, The Second School of Medicine, Wenzhou Medical University, Wenzhou, China.

Objective: Glomus tumors are benign with unique triad of symptoms; however, the delayed diagnosis of these tumors is common. We investigated the possible risk factors for the misdiagnosis of digital glomus tumors, with an aim to treat these patients on time.

Methods: We conducted a retrospective cohort study of 104 patients with digital glomus tumors from October 2009 to February 2021. Read More

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Gastroesophageal Glomus Tumors: Clinicopathologic and Molecular Genetic Analysis of 26 Cases With a Proposal for Malignancy Criteria.

Am J Surg Pathol 2022 Jun 15. Epub 2022 Jun 15.

Department of Pathology, Brigham and Women's Hospital, and Harvard Medical School, Boston, MA.

Although criteria for malignancy have been established for glomus tumors of soft tissue, there are no accepted criteria for gastroesophageal glomus tumors, the behavior of which is considered to be unpredictable. Recently, both benign and aggressive gastroesophageal glomus tumors have been shown to harbor CARMN::NOTCH2 fusions, but, as yet, there are no described genetic features that predict clinical behavior. Here, we evaluated 26 gastroesophageal glomus tumors to investigate histologic and genetic features that might predict malignant behavior. Read More

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Gastric Glomus Tumor: A Rare Cause of Acute Blood Loss Anemia.

Cureus 2022 Apr 26;14(4):e24511. Epub 2022 Apr 26.

Hospital Medicine, Albert Einstein College of Medicine, New York City, USA.

Gastric glomus tumors (GGTs) are rare mesenchymal neoplasms that arise from cells of the glomus body. These occur in the submucosa of the gastric wall and are usually benign in nature. However, it is difficult to predict tumor behavior due to the lack of reliable histological features. Read More

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[Glomus tumors of the fingers].

Rev Prat 2022 Mar;72(3):313-316

"Clinique Jouvenet, Capio-Ramsay Santé, Paris Hôpital privé Paul-d'Égine, SOS Mains, Val-de-Marne, Capio-Ramsay Santé, Champigny-sur-Marne Maison de santé pluridisciplinaire " La Francilienne ", SOS Mains, antenne Seine-et-Marne, Pontault-Combault".

"Glomus tumors of the fingers. Glomus tumors of the fingers are benign lesions. The main symptom is a paroxysmal pain with particular hypersensiti¬vity to temperature changes. Read More

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Unusual glomus tumor of the lower leg: A case report.

World J Clin Cases 2022 Apr;10(11):3485-3489

Department of Orthopedics, Zhongnan Hospital of Wuhan University, Wuhan 430000, Hubei Province, China.

Background: Glomus tumors are rare neoplasms, usually found on the fingers or toes. Glomus tumours that occur in the lower leg are even rarer and is likely to be misdiagnosed or underdiagnosed. This article will document the diagnosis, treatment, and follow-up of a rare glomus tumor of the lower leg, which had been misdiagnosed for up to 15 years. Read More

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Sellar Glomus Tumor Misdiagnosed as Pituitary Adenoma: A Case Report and Review of the Literature.

Front Endocrinol (Lausanne) 2022 4;13:895054. Epub 2022 May 4.

Department of Neurosurgery, Center of Pituitary Tumor, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Glomus tumor is a rare mesenchymal tumor with an organ-like structure. Sellar glomus tumors are extremely rare with only six reported cases in the literature. Because of the lack of special clinical manifestations and imaging features, the disorder may be easily misdiagnosed as other sellar tumors, especially pituitary adenomas. Read More

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A Four-Generational Report on Hereditary Head and Neck Paraganglioma.

Cureus 2022 Apr 14;14(4):e24143. Epub 2022 Apr 14.

Otolaryngology - Head and Neck Surgery, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, DEU.

Background This article investigates the inheritance, penetrance, clinical presentation, and therapeutic outcomes of hereditary head and neck paragangliomas (HNPGLs) by offering a four-generational report of an 18-member family affected by this rare condition. Methodology Information was compiled by examination of patients and a review of medical records and correspondence (retrospective case series). Results Six members of the 18-member family were diagnosed with HNPGL between 2002 and 2018. Read More

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Rare malignant glomus tumor of the esophagus with pulmonary metastasis: a case report.

AME Case Rep 2022 25;6:20. Epub 2022 Apr 25.

Department of Medicine, University of California Los Angeles, Los Angeles, CA, USA.

Background: Glomus tumors are typically benign soft tissue neoplasms that arise in peripheral cutaneous structures. Visceral organ involvement is exceedingly rare.

Case Description: Here we present a case of malignant glomus tumor of the esophagus with pulmonary metastases in a 57-year-old woman presenting with three weeks of progressive dysphagia, epigastric pain, and 35-pound weight loss. Read More

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Identifying the uncommon solitary fibrous tumour in a rare location - A case report.

Int J Surg Case Rep 2022 May 8;94:107058. Epub 2022 Apr 8.

Department of Surgery, Armidale Rural Referral Hospital, 226 Rusden street, Armidale, NSW 2350, Australia.

Introduction And Importance: The authors describe a case work up of an unusual natal cleft soft tissue tumour which eventually was concluded as solitary fibrous tumour. Solitary fibrous tumour is an uncommon fibroblastic tumour which commonly presents in pleural region and very rarely in extrapleural location such as natal cleft. Accurate identification of this tumour, considering the indeterminate nature of the tumour irrespective of the location, avoided misdiagnosis and played a vital role in follow up management of the patient. Read More

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Computed tomography features and clinicopathological characteristics of gastric glomus tumor.

BMC Gastroenterol 2022 Apr 9;22(1):174. Epub 2022 Apr 9.

Department of Radiology, The First Affiliated Hospital of Zhengzhou University, No. 1, East Jianshe Road, Zhengzhou, 450052, Henan Province, China.

Background: Gastric glomus tumor (GGT) is a rare neoplasm that is difficult to distinguish from other gastric submucosal tumors due to a lack of diagnostic experience. The goal of this study was to better understand GGT by looking at its clinicopathological features, computed tomography (CT) features, and differential diagnosis.

Methods: The clinical data and CT findings of 21 pathologically confirmed GGT patients were examined. Read More

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Total-Body Irradiation Is Associated With Increased Incidence of Mesenchymal Neoplasia in a Radiation Late Effects Cohort of Rhesus Macaques (Macaca mulatta).

Int J Radiat Oncol Biol Phys 2022 Mar 28. Epub 2022 Mar 28.

Department of Pathology, Section on Comparative Medicine; Department of Radiation Oncology, Wake Forest School of Medicine, Winston-Salem, North Carolina. Electronic address:

Purpose: Cancer is a severe delayed effect of acute radiation exposure. Total-body irradiation has been associated with an increased risk of solid cancer and leukemia in Japanese atomic bomb survivors, and secondary malignancies, such as sarcoma, are a serious consequence of cancer radiation therapy. The radiation late effects cohort (RLEC) of rhesus macaques (Macaca mulatta) is a unique resource of more than 200 animals for studying the long-term consequences of total-body irradiation in an animal model that closely resembles humans at the genetic and physiologic levels. Read More

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Incidental superficial soft tissue epithelioid angioleiomyoma.

J Cutan Pathol 2022 Mar 31. Epub 2022 Mar 31.

Service of Anatomical Pathology, Marqués de Valdecilla University Hospital-IDIVAL, Santander, Spain.

Epithelioid angioleiomyoma (EALM) is rare in the skin and subcutaneous tissues. To the best of our knowledge, only two previous cases of this tumor have been reported. We document here the case of an 83-year-old woman who underwent complete removal of a squamous cell carcinoma of the retromolar trigone and lymph node dissection of the neck. Read More

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Mesenchymal tumors of the stomach: radiologic and pathologic correlation.

Abdom Radiol (NY) 2022 Jun 26;47(6):1988-2003. Epub 2022 Mar 26.

Department of Pathology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, 10029, India.

Mesenchymal tumors of the stomach are uncommon, with gastrointestinal stromal tumor (GIST) being the most common among them. Majority of the tumors may arise from cells of Cajal, smooth muscle cells, neural cells, totipotent stem cells, adipocytes or fibroblasts. Imaging plays an important role not only in staging but also in characterizing these tumors. Read More

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Unusual Location of Pulp Glomus Tumor: A Case Study and Literature Review.

Plast Reconstr Surg Glob Open 2022 Mar 17;10(3):e4206. Epub 2022 Mar 17.

Division of Plastic Surgery, Department of Surgery, King Saud University Medical City, King Saud University, Riyadh, Saudi Arabia.

Glomus tumors are painful, benign tumors that develop from the glomus bodies. They account for less than 1% of tumors in hand, and less than 10% present in the pulp of the digits. Cold hypersensitivity, increased pinprick sensitivity, and paroxysmal pain are common glomus tumor symptoms. Read More

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Glomus tumors around or in the knee: a case report and literature review.

BMC Surg 2022 Mar 16;22(1):97. Epub 2022 Mar 16.

Department of Orthopedic Surgery, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Peking Union Medical College & Chinese Academy of Medical Sciences, No. 1 Shuaifuyuan Rd, Beijing, 100730, China.

Background: Glomus tumors commonly affect the extremities, especially subungual. And glomus tumors rarely occur around knee, which are often misdiagnosed. A lack of experience with glomus tumors is likely the cause. Read More

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Extraskeletal Mesenchymal Chondrosarcoma of Central Nervous System - A Rare but Aggressive Tumor: Analysis of Five Cases.

Neurol India 2022 Jan-Feb;70(1):285-288

Department of Neurosurgery, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.

Background: Extraskeletal mesenchymal chondrosarcoma (MCS) of the central nervous system (CNS) is extremely rare. Herein, we present the clinicopathological features of five CNS extraskeletal MCS.

Material And Methods: Over the past 10 years, five cases of CNS MCS have been retrieved from in the archives of histopathology department. Read More

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Recurrent Glomus Jugulare Tumor Invading the Cerebellum on 68Ga-DOTATATE PET/CT.

Clin Nucl Med 2022 May;47(5):e406-e407

From the Department of Nuclear Medicine, Marmara University Pendik Training and Research Hospital, Istanbul, Turkey.

Abstract: Glomus tumors are rare, slow-growing extra-adrenal paragangliomas of the head and neck. Treatment and prevention of neurological deficits become more difficult as these tumors aggressively grow in size and infiltrate adjacent anatomical structures. Because glomus tumors are paragangliomas of neuroendocrine origin, 68Ga-DOTATATE PET/CT can be used as imaging method in the diagnosis and follow-up. Read More

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HyperArc VMAT stereotactic radiotherapy for locally recurrent previously-irradiated head and neck cancers: Plan quality, treatment delivery accuracy, and efficiency.

J Appl Clin Med Phys 2022 May 7;23(5):e13561. Epub 2022 Mar 7.

Medical Physics Graduate Program, Department of Radiation Medicine, University of Kentucky, Lexington, Kentucky, USA.

Purpose: This paper demonstrates the clinical feasibility and efficacy of HyperArc VMAT treatments for locally recurrent, locally advanced, or previously irradiated head and neck cancers treated with stereotactic radiotherapy (SRT).

Materials/methods: First, an anthropomorphic SRS head phantom from the MD Anderson's IROC credentialing laboratory containing a 1.9 cm diameter spherical target, including in vivo dosimetry system, was imaged, planned, and irradiated (25 Gy in 1 fraction) using HyperArc VMAT with a 6 MV flattening filter free (FFF) beam. Read More

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Post-Embolization Excision of Glomus Tympanicum: A Case Report.

Cureus 2022 Jan 19;14(1):e21414. Epub 2022 Jan 19.

Otorhinolaryngology Head Neck Surgery, Florence Hospital, Srinagar, IND.

Glomus tympanicum is a slow-growing benign tumor that can be locally destructive, spreading along the path of least resistance. Conventionally seen as soft tissue mass in the middle ear, it is difficult to distinguish glomus tympanicum from other soft tissue masses of the tympanic cavity, especially as it hides behind an intact tympanic membrane. The primary diagnostic modalities are CT scan and MRI for evaluation of the exact anatomical extent and size of the glomus tumors. Read More

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January 2022

Stereotactic Radiosurgery for Glomus Jugulare Tumors: Systematic Review and Meta-Analysis.

World Neurosurg 2022 Jun 19;162:e49-e57. Epub 2022 Feb 19.

Department of Neurosurgery, Ronald Reagan UCLA Medical Center, Los Angeles, California, USA; Department of Radiation Oncology, Ronald Reagan UCLA Medical Center, Los Angeles, California, USA; Department of Head and Neck Surgery, Ronald Reagan UCLA Medical Center, Los Angeles, California, USA; Office of the Patient Experience, Ronald Reagan UCLA Medical Center, Los Angeles, California, USA; UCLA Jonsson Comprehensive Cancer Center, Ronald Reagan UCLA Medical Center, Los Angeles, California, USA; Department of Neurosurgery, Harbor-UCLA Medical Center, Torrance, California, USA; Los Angeles Biomedical Research Institute, Harbor-UCLA Medical Center, Torrance, California, USA. Electronic address:

Background: Glomus jugulare tumors (GJTs) are benign paragangliomas of the jugular foramen. Traditional management of these tumors involves surgical resection; however, considering the proximity of these tumors to important neurovasculature, stereotactic radiosurgery (SRS) may be an appropriate noninvasive treatment to consider. The aim of this meta-analysis was to evaluate SRS as a treatment option for GJTs. Read More

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Endoscopic management of subepithelial lesions including neuroendocrine neoplasms: European Society of Gastrointestinal Endoscopy (ESGE) Guideline.

Endoscopy 2022 04 18;54(4):412-429. Epub 2022 Feb 18.

Department of Gastroenterology and Hepatology, Leiden University Medical Center, Leiden, The Netherlands.

1: ESGE recommends endoscopic ultrasonography (EUS) as the best tool to characterize subepithelial lesion (SEL) features (size, location, originating layer, echogenicity, shape), but EUS alone is not able to distinguish among all types of SEL.Strong recommendation, moderate quality evidence. 2: ESGE suggests providing tissue diagnosis for all SELs with features suggestive of gastrointestinal stromal tumor (GIST) if they are of size > 20 mm, or have high risk stigmata, or require surgical resection or oncological treatment. Read More

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Paragangliomas of the head and neck.

J Oral Pathol Med 2022 Feb 18. Epub 2022 Feb 18.

Head and Neck Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA.

Paragangliomas are rare neuroendocrine tumors that can be found from the skull base to the pelvis. Head and neck paragangliomas have been historically treated with surgery. However, surgical resection adds risk of injury to vascular structures and cranial nerves that can lead to morbidity such as hoarseness, dysarthria, dysphagia, or aspiration. Read More

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February 2022

Contemporary management of paragangliomas of the head and neck.

Laryngoscope Investig Otolaryngol 2022 Feb 26;7(1):93-107. Epub 2021 Nov 26.

Department of Otolaryngology-Head and Neck surgery Beaumont Hospital Dublin Ireland.

Head and neck paragangliomas (HNPGLs) are rare neuroendocrine tumors typically arising from nonsecretory head and neck parasympathetic ganglia. Historically thought of as aggressive tumors that warranted equally aggressive surgical intervention, evidence has emerged demonstrating that the vast majority of HNPGLs are slow growing and indolent. It is also now recognized that a large proportion of HNPGLs are hereditary with succinate dehydrogenase gene mutations typically implicated. Read More

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February 2022

Cytologic analysis of a glomus tumor in the left second toe: Case report.

Diagn Cytopathol 2022 Jun 9;50(6):E170-E173. Epub 2022 Feb 9.

Department of Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston, South Carolina, USA.

We present a 66-year-old female with a glomus tumor diagnosed by fine-needle aspiration (FNA) at the subungual region of her left second toe. Cytologic findings include cohesive clusters of round, uniform cells with scant cytoplasm. Nuclei were monotonous with fine chromatin. Read More

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Three-Corridors Procedure to Operate in the Infralabyrinthine Cervico-Jugulo-Carotico-Tympanic Area.

ORL J Otorhinolaryngol Relat Spec 2022 3;84(2):147-152. Epub 2022 Feb 3.

Department of Otolaryngology Head and Neck Surgery, Faculty of Medicine, Istanbul Medipol University, Istanbul, Turkey.

Introduction: The aim of the study was to present the results of our experience in three-corridors procedures applied for the tumors and inflammatory lesions of the infralabyrinthine cervico-jugulo-carotico-tympanic area.

Methods: The lesions located in the infralabyrinthine cervico-jugulo-carotico-tympanic area were operated in 13 patients using the 3-corridors technique. The anatomical and functional integrity of the external and middle ears and the facial nerve (FN) could be preserved. Read More

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