633 results match your criteria Glomerulonephritis Poststreptococcal


Glomerular Deposition of Nephritis-Associated Plasmin Receptor (NAPlr) and Related Plasmin Activity: Key Diagnostic Biomarkers of Bacterial Infection-related Glomerulonephritis.

Int J Mol Sci 2020 Apr 8;21(7). Epub 2020 Apr 8.

Kidney Disease Center, Department of Nephrology and Blood Purification, Tokyo Medical University Hachioji Medical Center, Hachioji, Tokyo 193-0998, Japan.

It is widely known that glomerulonephritis (GN) often develops after the curing of an infection, a typical example of which is GN in children following streptococcal infections (poststreptococcal acute glomerulonephritis; PSAGN). On the other hand, the term "infection-related glomerulonephritis (IRGN)" has recently been proposed, because infections are usually ongoing at the time of GN onset in adult patients, particularly in older patients with comorbidities. However, there has been no specific diagnostic biomarker for IRGN, and diagnosis is based on the collection of several clinical and pathological findings and the exclusion of differential diagnoses. Read More

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http://dx.doi.org/10.3390/ijms21072595DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7178002PMC

Influenza a H1N1 associated acute glomerulonephritis in an adolescent.

IDCases 2020 15;19:e00659. Epub 2019 Oct 15.

Department of Pediatrics, Thriasio General Hospital, Athens, Greece.

Influenza virus primarily affects the respiratory system. It rarely causes extrapulmonary complications, with otitis media and febrile seizures being the most common in children. Acute glomerulonephritis as a complication of H1N1 influenza virus infection has been described only sporadically. Read More

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http://dx.doi.org/10.1016/j.idcr.2019.e00659DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7093738PMC
October 2019

[Infections-associated Glomerulonephritis].

Authors:
Martin Kimmel

Dtsch Med Wochenschr 2020 Feb 18;145(4):240-247. Epub 2020 Feb 18.

Glomerulonephritis, secondary to bacterial, or, more rarely, viral or parasitic infections, is called infection-associated. The epidemiology of infection-associated glomerulonephritis has changed in recent decades. For a long time, the classic form has been acute poststreptococcal glomerulonephritis (APGN), but in developed countries its incidence has declined sharply. Read More

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http://dx.doi.org/10.1055/a-0974-9420DOI Listing
February 2020

Crescentic poststreptococcal acute glomerulonephritis accompanied by small vessel vasculitis: case report of an elderly male.

BMC Nephrol 2019 12 18;20(1):471. Epub 2019 Dec 18.

Department of Nephrology and Dialysis, Kitano Hospital, Tazuke Kofukai Medical Research Institute, 2-4-20 Ohgimachi, Kita-ku, Osaka, 530-8480, Japan.

Background: Poststreptococcal acute glomerulonephritis (PSAGN) in the elderly tends to have a severe clinical course and often presents with crescentic necrotizing glomerulonephritis in the renal biopsy. However, vasculitis lesions are unusual.

Case Presentation: We present a 71-year-old man who was admitted to our hospital for a recurrent gout attack with a rapid decline of renal function. Read More

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http://dx.doi.org/10.1186/s12882-019-1663-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921464PMC
December 2019

Prevalence, Clinical Features and Antibiotic Susceptibility of Group A Streptococcal Skin Infections in School Children in Urban Western and Northern Uganda.

Pediatr Infect Dis J 2019 12;38(12):1183-1188

Heart Institute, Cincinnati Children's Hospital Medical Center.

Background: Group A Streptococcus (GAS) skin infections can lead to invasive sepsis, poststreptococcal glomerulonephritis, and potentially rheumatic heart disease (RHD). Within a study to identify predisposing factors of RHD in Ugandan schoolchildren, we determined the prevalence of skin infections and assessed the clinical features and antibiotic susceptibility of GAS skin infection.

Methods: Cross-sectional study conducted at 3 urban primary schools in Western and Northern Uganda in March 2017. Read More

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http://dx.doi.org/10.1097/INF.0000000000002467DOI Listing
December 2019
7 Reads

Glyceraldehyde-3-phosphate dehydrogenase of induces infection-related glomerulonephritis
.

Clin Nephrol 2019 Nov;92(5):263-272

Infection-related glomerulonephritis (IRGN) was previously thought to be due mostly to species, but is now known to be caused by a variety of other pathogens. Nephritis-associated plasmin receptor (NAPlr) was originally isolated from group A streptococci as the protein responsible for acute poststreptococcal glomerulonephritis, and was shown to be identical to streptococcal glyceraldehyde-3-phosphate dehydrogenase (GAPDH). Here, we describe a 7-year-old boy diagnosed with IRGN presenting with acute nephritic syndrome. Read More

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http://dx.doi.org/10.5414/CN109786DOI Listing
November 2019
2 Reads

Post-Streptococcal Reactive Arthritis.

Curr Rheumatol Rev 2020 ;16(1):2-8

Department of Rheumatology, Queen's University, Kingston, ON, Canada.

Introduction: Post-Streptococcal Reactive Arthritis (PSRA) is defined as inflammatory arthritis of ≥1 joint associated with a recent group A streptococcal infection in a patient who does not fulfill the Jones criteria for the diagnosis of Acute Rheumatic Fever (ARF).

Methods: In this narrative review, we conducted a systematic search on MEDLINE, EMBASE, Cochrane Library and Google Scholar using the words poststreptococcal reactive arthritis. The search covered the time period between 1982 and 2016. Read More

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http://www.eurekaselect.com/174188/article
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http://dx.doi.org/10.2174/1573397115666190808110337DOI Listing
January 2020
4 Reads

Extrarenal Immune-Mediated Disorders Linked with Acute Poststreptococcal Glomerulonephritis: a Systematic Review.

Clin Rev Allergy Immunol 2019 Oct;57(2):294-302

Pediatric Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

Streptococcus A infections have been associated with immune-mediated sequelae including acute glomerulonephritis, acute rheumatic fever, thrombocytopenia, hemolytic anemia, Henoch-Schönlein purpura, arthritis, uveitis, guttate psoriasis, and erythema nodosum. Available reviews do not report the occurrence of acute poststreptococcal glomerulonephritis in association with one of the mentioned conditions. We performed a systematic review of the literature on extrarenal immune-mediated disorders associated with acute poststreptococcal glomerulonephritis. Read More

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http://dx.doi.org/10.1007/s12016-019-08761-wDOI Listing
October 2019
9 Reads

Ectoparasites: Scabies.

J Am Acad Dermatol 2020 Mar 13;82(3):533-548. Epub 2019 Jul 13.

Department of Dermatology, University of California, San Francisco, San Francisco, California; International Alliance for the Control of Scabies, Parkville, Australia. Electronic address:

Scabies is an ectoparasitic dermatosis caused by Sarcoptes scabiei var. hominis and is a public health issue in all countries regardless of socioeconomic status. In high-income countries, delays in diagnosis can lead to institutional outbreaks; in low- and middle-income countries, poor access to health care contributes to disease undertreatment and long-term systemic sequelae. Read More

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http://dx.doi.org/10.1016/j.jaad.2019.05.109DOI Listing
March 2020
15 Reads

A Presumed Etiology of Kawasaki Disease Based on Epidemiological Comparison With Infectious or Immune-Mediated Diseases.

Front Pediatr 2019 21;7:202. Epub 2019 May 21.

Department of Pediatrics, College of Medicine, The Catholic University of Korea, Seoul, South Korea.

Kawasaki disease (KD) may be associated with infection of unknown pathogen(s). For predicting of the etiology of KD, we evaluated epidemiological characteristics in KD, common infectious diseases and immune-mediated diseases in childhood. We respectively, reviewed the data of patients with KD, influenza, aseptic meningitis, exanthem subitum (ES), (MP) pneumonia, acute pyelonephritis (APN), Henoch-Schönlein purpura (HSP), acute poststreptococcal glomerulonephritis (APSGN), and childhood asthma. Read More

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http://dx.doi.org/10.3389/fped.2019.00202DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536658PMC
May 2019
27 Reads

Potential for Molecular Testing for Group A Streptococcus to Improve Diagnosis and Management in a High-Risk Population: A Prospective Study.

Open Forum Infect Dis 2019 Apr 26;6(4):ofz097. Epub 2019 Feb 26.

Menzies School of Health Research, Charles Darwin University.

Background: In high-burden settings, guidelines recommend antibiotic treatment for all suspected group A (GAS) infections to prevent rheumatic fever and poststreptococcal glomerulonephritis. Highly sensitive rapid GAS tests could reduce unnecessary antibiotic use in these settings.

Methods: This was a prospective study of the Xpert Xpress Strep A (Cepheid) molecular test compared with culture of throat swab samples collected at a referral hospital in northern Australia. Read More

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http://dx.doi.org/10.1093/ofid/ofz097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469435PMC
April 2019
11 Reads

Infections Caused by Group C and G Streptococcus ( subsp. and Others): Epidemiological and Clinical Aspects.

Authors:
Gio J Baracco

Microbiol Spectr 2019 03;7(2)

University of Miami Miller School of Medicine and Miami Veterans Affairs Healthcare System, Miami, FL 33125.

Streptococci carrying serogroup C and G antigens, and in particular, subsp. (SDSE), are emerging human pathogens that are increasingly isolated from patients with a myriad of infections that range from mundane to life-threatening. SDSE is microbiologically similar to . Read More

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http://dx.doi.org/10.1128/microbiolspec.GPP3-0016-2018DOI Listing
March 2019
12 Reads

[Zwiększenie częstości zachorowania na ostre popaciorkowcowe kłębuszkowe zapalenie nerek w pierwszej połowie roku 2018 - doświadczenie jednego ośrodka].

Pol Merkur Lekarski 2019 Mar;46(273):115-121

Medical University of Warsaw: Department of Pediatrics and Nephrology.

Acute poststreptococcal glomerulonephritis (APSGN) is a complication of infection with group A beta-hemolytic streptococcus. The disease manifests as microscopic/gross hematuria, arterial hypertension, edema, and acute kidney injury and has most commonly self-limiting course.

Aim: The aim of study was the analysis of clinical course of APSGN in period of increased incidence in the first half of 2018. Read More

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March 2019
12 Reads

A Controlled Human Infection Model of Group A Pharyngitis: Which Strain and Why?

mSphere 2019 02 13;4(1). Epub 2019 Feb 13.

Tropical Diseases, Murdoch Children's Research Institute, Melbourne, Victoria, Australia

Group A (GAS) is a major cause of global infection-related morbidity and mortality. A modern controlled human infection model (CHIM) of GAS pharyngitis can accelerate vaccine development and pathogenesis research. A robust rationale for strain selection is central to meeting ethical, scientific, and regulatory requirements. Read More

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http://dx.doi.org/10.1128/mSphere.00647-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374595PMC
February 2019
25 Reads

Spectrum of glomerular diseases in Arab countries: A systematic review.

Saudi J Kidney Dis Transpl 2018 Nov-Dec;29(6):1256-1266

Department of Allied Health Sciences, College of Medicine and Health Sciences, Sultan Qaboos University, Muscat, Sultanate of Oman.

According to the best of our knowledge, there is no review compiling incidence of glomerular disease in all Arab countries. Most of the Arab countries do not have a national renal biopsy registry. In addition, there is scanty data available on the epidemiology of glomerular diseases in Arab countries. Read More

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http://www.sjkdt.org/text.asp?2018/29/6/1256/248285
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http://dx.doi.org/10.4103/1319-2442.248285DOI Listing
October 2019
38 Reads

Infection-Related Glomerulonephritis.

Pediatr Clin North Am 2019 02;66(1):59-72

Division of Nephrology, Boston Children's Hospital, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA.

Acute postinfectious glomerulonephritis or infection-related glomerulonephritis has been associated with several viral or bacterial infections. Group A beta-hemolytic streptococcal infection is the prototypical cause of postinfectious glomerulonephritis and the main focus of this discussion. The clinical spectrum can vary widely, from asymptomatic microscopic hematuria incidentally detected on routine urinalysis to rapidly progressive glomerulonephritis with acute kidney injury requiring emergent dialysis. Read More

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http://dx.doi.org/10.1016/j.pcl.2018.08.005DOI Listing
February 2019
45 Reads

Poststreptococcal Glomerulonephritis and Antibiotics: A Fresh Look at Old Data.

Clin Pediatr (Phila) 2019 01 10;58(1):10-12. Epub 2018 Aug 10.

2 West Virginia University, Morgantown, WV, USA.

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http://dx.doi.org/10.1177/0009922818793345DOI Listing
January 2019
18 Reads

Outbreak of Glomerulonephritis Caused by Streptococcus zooepidemicus SzPHV5 Type in Monte Santo de Minas, Minas Gerais, Brazil.

J Clin Microbiol 2018 10 25;56(10). Epub 2018 Sep 25.

Laboratório de Toxina de Alimentos, Fundação Ezequiel Dias, Belo Horizonte, MG, Brazil.

is an emerging and opportunistic zoonotic pathogen which plays an important role in the development of severe and life-threatening diseases and is potentially capable of triggering large glomerulonephritis outbreaks. Between December 2012 and February 2013, 175 cases of glomerulonephritis were confirmed in the town of Monte Santo de Minas, MG, Brazil. During the outbreak, 19 isolates of were recovered, 1 from ice cream, 2 from the oropharynx of food handlers, and 16 from patients affected by acute poststreptococcal glomerulonephritis (APSGN). Read More

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http://dx.doi.org/10.1128/JCM.00845-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156306PMC
October 2018
15 Reads

Peritoneal Infections in Children Undergoing Acute Peritoneal Dialysis at a Tertiary/Quaternary Central Hospital in Kwazulu-Natal, South Africa.

Perit Dial Int 2018 Nov-Dec;38(6):413-418. Epub 2018 Jul 31.

Department of Paediatrics and Child Health, Nelson R Mandela School of Medicine, Faculty of Health Sciences, University of KwaZulu-Natal, Durban, South Africa.

Background: In a resource-limited setting, acute peritoneal dialysis (APD) is the modality of choice as a form of renal replacement therapy in children with acute kidney injury (AKI). However, there is a high risk of peritonitis that causes significant morbidity and mortality. Data on PD and peritonitis in developing countries are scarce. Read More

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http://www.pdiconnect.com/lookup/doi/10.3747/pdi.2017.00284
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http://dx.doi.org/10.3747/pdi.2017.00284DOI Listing
March 2019
21 Reads

Acute infection-related glomerulonephritis with disseminated gonococcal infection in a 13-year-old girl.

BMJ Case Rep 2018 Jul 18;2018. Epub 2018 Jul 18.

Department of Pediatrics, NYU Winthrop Hospital, Mineola, New York, USA.

Infection-related glomerulonephritis results from glomerular immune complex deposition due to a variety of potential pathogens. Poststreptococcal glomerulonephritis is the best known example. We present a case of acute infection-related glomerulonephritis associated with disseminated gonococcal infection in a sexually active 13-year-old girl, the first report of such an association in the absence of endocarditis. Read More

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http://dx.doi.org/10.1136/bcr-2018-225371DOI Listing
July 2018
18 Reads

Poststreptococcal glomerulonephritis with atypical hemolytic uremic syndrome: An unusual presentation.

Saudi J Kidney Dis Transpl 2018 May-Jun;29(3):728-731

Department of Nephrology, Muljibhai Patel Urological Hospital, Nadiad, Gujarat, India.

A 14-year-old female presented with oliguric dialysis requiring kidney injury due to acute poststreptococcal glomerulonephritis (PSGN) with hypertension strongly suggestive of atypical hemolytic uremic syndrome (aHUS) with microangiopathic hemolytic anemia and elevated factor H antibody levels. Renal biopsy revealed crescentic glomerulonephritis with typical subepithelial, intramembranous and mesangial electron-dense deposits (humps) on electron microscopy. She was treated with glucocorticoids following which she recovered, remained dialysis free and her Factor H antibody levels and depressed complement 3 levels normalized. Read More

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http://www.sjkdt.org/text.asp?2018/29/3/728/235201
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http://dx.doi.org/10.4103/1319-2442.235201DOI Listing
October 2019
47 Reads

De Novo Postinfectious Glomerulonephritis Secondary to Nephritogenic Streptococci as the Cause of Transplant Acute Kidney Injury: A Case Report and Review of the Literature.

Case Rep Transplant 2018 31;2018:2695178. Epub 2018 May 31.

Division of Nephrology-Hypertension, University of California San Diego, San Diego, CA, USA.

Acute kidney injury is common among kidney transplant recipients. Postinfectious glomerulonephritis secondary to nephritogenic streptococci is one of the oldest known etiologies of acute kidney injury in native kidneys but rarely reported among kidney transplant recipients. This report is of a biopsy-proven case of acute kidney injury in a renal allograft recipient caused by de novo poststreptococcal glomerulonephritis. Read More

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http://dx.doi.org/10.1155/2018/2695178DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6000912PMC
May 2018
44 Reads

Poststreptococcal Illness: Recognition and Management.

Am Fam Physician 2018 04;97(8):517-522

University of Tennessee Family Medicine Residency Program, Jackson, TN, USA.

Group A beta-hemolytic streptococcus can cause several postinfectious, nonsuppurative immune- mediated diseases including acute rheumatic fever, poststreptococcal reactive arthritis, pediatric autoimmune neuropsychiatric disorders, and poststreptococcal glomerulonephritis. Except for sporadic outbreaks, poststreptococcal autoimmune syndromes occur most commonly in sub-Saharan Africa, India, Australia, and New Zealand. Children younger than three years are rarely affected by group A streptococcus pharyngitis or rheumatic fever, and usually do not require testing. Read More

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April 2018
18 Reads

Poststreptococcal Glomerulonephritis With Unusual Lung Involvement.

J Clin Rheumatol 2019 09;25(6):e87-e89

Department of Rheumatology, University Hospital Basel, Basel, Switzerland Department of Laboratory Medicine, University Hospital Basel, Basel, Switzerland Department of Pathology, University Hospital Basel, Basel, Switzerland Department of Radiology, University Hospital Basel Basel, Switzerland Department of Nephrology and Transplantation Medicine, University Hospital Basel, Basel, Switzerland Department of Rheumatology, University Hospital Basel, Basel, Switzerland.

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http://dx.doi.org/10.1097/RHU.0000000000000734DOI Listing
September 2019
19 Reads

Anticardiolipin antibodies in concurrent poststreptococcal glomerulonephritis and autoimmune hemolytic anemia: A case report.

Arch Argent Pediatr 2018 Apr;116(2):e288-e291

Department of Pedi-Nephrology, Xinhua Hospital affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China.

We present a case of acute post-streptococcal glomerulonephritis (APSGN) with autoimmune hemolytic anemia (AIHA). Along with the classic findings of APSGN, the patient had a positive direct antiglobulin test and an anticardiolipin antibody without any typical clinical manifestations of antiphospholipid syndrome (APS). This case raises questions of the relationship between Streptococcus and the development of autoimmune hemolytic anemia in children. Read More

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http://www.sap.org.ar/docs/publicaciones/archivosarg/2018/v1
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http://dx.doi.org/10.5546/aap.2018.eng.e288DOI Listing
April 2018
19 Reads

A Pediatric Case of Diffuse Alveolar Hemorrhage Secondary to Poststreptococcal Glomerulonephritis.

Case Rep Crit Care 2017 20;2017:1050284. Epub 2017 Dec 20.

Division of Pediatric Respirology, University of Saskatchewan, Saskatoon, SK, Canada.

This report summarizes a case of a 4-year-old girl with poststreptococcal glomerulonephritis and diffuse alveolar hemorrhage, an atypical presentation in this age group and type of vasculitic disease. We propose that her rapid improvement in clinical status was due to her treatment, continuous renal replacement therapy (CRRT). This mechanism would have impacted recovery by removing factors such as endothelial microparticles, superantigens, and immune complexes that have been postulated as the pulmonary-renal link. Read More

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http://dx.doi.org/10.1155/2017/1050284DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5750514PMC
December 2017
18 Reads

Effect of the 2015 earthquake on pediatric inpatient pattern at a tertiary care hospital in Nepal.

BMC Pediatr 2018 02 5;18(1):28. Epub 2018 Feb 5.

American International Medical University, Gros Islet, Saint Lucia.

Background: Earthquakes impact child health in many ways. Diseases occurring immediately following an earthquake have been studied in field based hospitals but studies on the inpatient disease pattern among children without trauma in a permanent hospital setup is lacking.

Methods: We examined the diagnoses of all children without trauma, admitted to Kanti Children's Hospital, Kathmandu for fifteen-week duration (from 4th week to end of the 18th week) following the 7. Read More

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http://dx.doi.org/10.1186/s12887-018-1008-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800012PMC
February 2018
19 Reads

Posterior reversible encephalopathy syndrome secondary to asymptomatic poststreptococcal glomerulonephritis in a child with sickle cell anemia: a case report.

J Med Case Rep 2018 Feb 1;12(1):24. Epub 2018 Feb 1.

Prince Sultan Oncology Center, King Salman Armed Forces Hospital, Tabuk, 100, Kingdom of Saudi Arabia.

Background: Posterior reversible encephalopathy syndrome is a neurotoxic condition that occurs as a result of the failure of posterior circulatory autoregulation in response to acute changes in blood pressure. Overperfusion with resultant disruption of the blood-brain barrier results in vasogenic edema, but not infarction. Posterior reversible encephalopathy syndrome can be the presenting feature of postinfectious glomerulonephritis, which has been reported in approximately 5% of hospitalized children, and it has been reported in very few cases of adult patients with sickle cell anemia. Read More

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http://dx.doi.org/10.1186/s13256-017-1559-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793438PMC
February 2018
17 Reads

Posterior Reversible Encephalopathy Syndrome Secondary to Acute PostStreptococcal Glomerulonephritis in a 12-year-old Girl.

J Coll Physicians Surg Pak 2018 Jan;28(1):80-81

Department of Pediatric Medicine Unit-1, Nishtar Hospital, Multan.

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http://dx.doi.org/10.29271/jcpsp.2018.01.80DOI Listing
January 2018
25 Reads

Infection-related glomerulonephritis in a renal allograft.

Saudi J Kidney Dis Transpl 2017 Nov-Dec;28(6):1421-1426

Department of Nephrology, Madras Medical College and Rajiv Gandhi Government General Hospital, Chennai, Tamil Nadu, India.

Infection-related glomerulonephritis (IRGN) is an immune-mediated glomerulo-nephritis, most commonly caused by bacterial infections. Although there is an increased incidence of infectious episodes in renal transplant recipients, IRGN as a cause of de novo glomerulonephritis is rarely seen probably due to impaired immunity. We hereby report a 28-year-old male renal transplant recipient, who developed IRGN following impetigenous skin lesions after six years of transplant. Read More

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http://dx.doi.org/10.4103/1319-2442.220864DOI Listing
July 2019
18 Reads

Clinical characteristics of hypertensive encephalopathy in pediatric patients.

Korean J Pediatr 2017 Aug 14;60(8):266-271. Epub 2017 Aug 14.

Department of Pediatrics, Chonbuk National University Medical School, Jeonju, Korea.

Purpose: The aim of this study was to assess the clinical characteristics of hypertensive encephalopathy according to the underlying etiologies in children.

Methods: We retrospectively evaluated 33 pediatric patients who were diagnosed as having hypertensive encephalopathy in Chonbuk National University Children's Hospital. Among the patients, 18 were excluded because of incomplete data or because brain magnetic resonance imaging (MRI) was not performed. Read More

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http://dx.doi.org/10.3345/kjp.2017.60.8.266DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638725PMC
August 2017
27 Reads

Group A streptococcal pharyngitis: Immune responses involved in bacterial clearance and GAS-associated immunopathologies.

J Leukoc Biol 2018 02 29;103(2):193-213. Epub 2017 Dec 29.

School of Chemistry and Molecular Biosciences, Australian Infectious Diseases Research Centre, The University of Queensland, Brisbane, Australia.

Streptococcus pyogenes, the Group A Streptococcus (GAS), is the most common cause of bacterial pharyngitis in children and adults. Innate and adaptive host immune responses are fundamental for defense against streptococcal pharyngitis and are central to the clinical manifestation of disease. Host immune responses also contribute to the severe poststreptococcal immune diseases that constitute the major disease burden for this organism. Read More

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http://doi.wiley.com/10.1189/jlb.4MR0617-227RR
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http://dx.doi.org/10.1189/jlb.4MR0617-227RRDOI Listing
February 2018
26 Reads

Concurrent Acute Glomerulonephritis and Retropharyngeal Abscess in 10 Year Boy: A Case Report.

J Clin Diagn Res 2017 Jul 1;11(7):SD13-SD14. Epub 2017 Jul 1.

Professor, Department of Radiodiagnosis, Pt B D Sharma PGIMS, Rohtak, Haryana, India.

Postinfectious Glomerulonephritis (PIGN) usually follows 1-2 weeks after respiratory tract infection and 4-6 weeks after skin infection. Acute Glomerulonephritis (AGN) is uncommon with simultaneous severe throat infections. We describe a 10-year-old boy who was presented with high grade fever, dysphagia and tender swelling over left side of neck. Read More

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http://dx.doi.org/10.7860/JCDR/2017/26421.10299DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5583899PMC
July 2017
41 Reads

Cardiac status in children with acute poststreptococcal glomerulonephritis.

Saudi J Kidney Dis Transpl 2017 Jul-Aug;28(4):830-835

Department of Pediatrics, Division of Pediatric Nephrology, Lokmanya Tilak Municipal Medical College and General Hospital, Mumbai, Maharashtra, India.

Acute poststreptococcal glomerulonephritis (PSGN) is the most common type of glomerulonephritis seen in children. It can affect multiple organs with heart being frequently involved. Yet, there are very few studies on cardiac status in children with PSGN and hence this study was conducted. Read More

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July 2019
20 Reads

A rare adult case of poststreptococcal acute glomerulonephritis with a retropharyngeal abscess.

CEN Case Rep 2017 May 27;6(1):118-123. Epub 2017 Mar 27.

Division of Nephrology, Department of Internal Medicine, Saga University Faculty of Medicine, 5-1-1 Nabeshima, Saga, Saga, 849-8501, Japan.

Retropharyngeal abscess is an infection involving the retropharyngeal space which is posterior to the pharynx and oesophagus, and it results as a complication of a primary infection elsewhere in the head and neck including the nasopharynx, paranasal sinuses, or middle ear, which drain lymph to the retropharyngeal lymph nodes. Their lymph nodes are prominent in children and atrophy with age. Therefore, retropharyngeal abscess is most frequently encountered in children, with 75% of cases occurring before the age of 5 years, and often in the first year of life. Read More

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http://dx.doi.org/10.1007/s13730-017-0256-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438820PMC
May 2017
42 Reads

Posterior reversible encephalopathy in an adult patient with poststreptococcal glomerulonephritis.

BMJ Case Rep 2017 Apr 17;2017. Epub 2017 Apr 17.

Department of Medicine, Metropolitan Hospital Center, New York, New York, USA.

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http://dx.doi.org/10.1136/bcr-2017-220043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5534978PMC
April 2017
14 Reads

Multiple Causes of Hyponatremia: A Case Report.

Med Princ Pract 2017 7;26(3):292-295. Epub 2017 Mar 7.

Clinic of Endocrinology, Diabetes and Metabolic Diseases, Clinical Center of Vojvodina, Novi Sad, Serbia.

Objective: To present a case with 4 different potential causes of hyponatremia.

Clinical Presentation And Intervention: The patient presented with the following symptoms: nausea, vomiting, diarrhea, and dark urine after drinking large amounts of fluids that included alcohol and caffeine. Laboratory, microbiological, and morphological examinations revealed the existence of severe hyponatremia and acute poststreptococcal glomerulonephritis. Read More

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http://dx.doi.org/10.1159/000468938DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5588416PMC
March 2018
17 Reads

Posterior reversible encephalopathy syndrome in children: a case series.

Turk Pediatri Ars 2016 Dec 1;51(4):217-220. Epub 2016 Dec 1.

Division of Pediatric Hematology, Necmettin Erbakan University Meram School of Medicine, Konya, Turkey.

Posterior reversible encephalopathy syndrome is characterized by hypertension, seizure, headache, clouding of consciousness, and visual disturbance, and is diagnosed in the presence of typical lesions on magnetic resonance imaging. We retrospectively evaluated five patients who were diagnosed as having posterior reversible encephalopathy syndrome and followed up in Meram Medical Faculty, Pediatric Intensive Care and Hematology wards, between January 2010 and January 2014. We reviewed the demographic and clinical data, and neuroimaging findings. Read More

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http://dx.doi.org/10.5152/TurkPediatriArs.2016.2192DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5242250PMC
December 2016
47 Reads

A Case of Thyroid Storm Associated with Cardiomyopathy and Poststreptococcal Glomerulonephritis.

Case Rep Pediatr 2016 27;2016:7192359. Epub 2016 Oct 27.

Department of Pediatric Endocrinology and Diabetes and Department of Pediatric Nephrology, The Children's Hospital at Montefiore, 3415 Bainbridge Ave., Bronx, NY 10467, USA.

Thyroid storm has a high mortality rate and is often associated with a precipitating factor such as intercurrent illness or infection. It is rare in pediatric patients. Cardiac disease in hyperthyroidism mostly manifests itself as tachycardia but more serious cardiac findings have also been described. Read More

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http://dx.doi.org/10.1155/2016/7192359DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5102721PMC
October 2016
48 Reads

Acute Cardiac Tamponade in a 58-Year-Old Male with Poststreptococcal Glomerulonephritis.

Methodist Debakey Cardiovasc J 2016 Sep;12(3):175-176

Virginia Commonwealth University Health System, Richmond, Virginia; Hunter Holmes McGuire VA Medical Center, Richmond, Virginia.

Pericarditis in conjunction with nephritis is an uncommon clinical scenario with a broad differential diagnosis. We present the case of a 58-year-old male who developed nephritis and pericardial effusion with tamponade physiology. In the following, we discuss the differential diagnosis for concomitant nephritis and pericarditis and discuss the work-up performed on our patient. Read More

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http://journal.houstonmethodist.org/doi/10.14797/mdcj-12-3-1
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http://dx.doi.org/10.14797/mdcj-12-3-175DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098576PMC
September 2016
36 Reads

Staphylococcus Infection-Associated GN - Spectrum of IgA Staining and Prevalence of ANCA in a Single-Center Cohort.

Clin J Am Soc Nephrol 2017 01 7;12(1):39-49. Epub 2016 Nov 7.

Department of Pathology, and.

Background And Objectives: Staphylococcus infection-associated GN (SAGN) is a well recognized disease entity, particularly because of the frequent IgA-dominant glomerular immunoglobulin staining on kidney biopsy. Biopsy features can resemble two other disease entities - primary IgA nephropathy and Henoch-Schönlein purpura nephritis - posing a diagnostic pitfall. This is clinically relevant because of the crucial difference in the therapeutic approach. Read More

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http://dx.doi.org/10.2215/CJN.05070516DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5220658PMC
January 2017
55 Reads

Serum myeloid-related protein 8/14 in minimal change- and glomerulonephritis-related nephrotic syndrome.

Pediatr Int 2016 Oct 26;58(10):998-1002. Epub 2016 Apr 26.

Department of Pediatrics, Fukushima Medical University School of Medicine, Fukushima City, Fukushima, Japan.

Background: Myeloid-related protein 8/14 (MRP8/14) forms stable heterodimers and is the major calcium-binding protein secreted by activated granulocytes and monocytes. We evaluated whether serum MRP8/14 level is a useful indicator for a differential diagnosis of glomerulonephritis (GN)- and minimal change disease (MC)- related nephrotic syndrome (NS).

Methods: Serum MRP8/14 complex was evaluated in 37 NS patients with MC or GN. Read More

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http://dx.doi.org/10.1111/ped.12947DOI Listing
October 2016
54 Reads

Acute Kidney Injury and Atypical Features during Pediatric Poststreptococcal Glomerulonephritis.

Int J Nephrol 2016 23;2016:5163065. Epub 2016 Aug 23.

Division of Nephrology, Department of Pediatrics, Nationwide Children's Hospital, Columbus, OH, USA.

The most common acute glomerulonephritis in children is poststreptococcal glomerulonephritis (PSGN) usually occurring between 3 and 12 years old. Hypertension and gross hematuria are common presenting symptoms. Most PSGN patients do not experience complications, but rapidly progressive glomerulonephritis and hypertensive encephalopathy have been reported. Read More

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http://www.hindawi.com/journals/ijn/2016/5163065/
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http://dx.doi.org/10.1155/2016/5163065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011525PMC
September 2016
31 Reads

Acute poststreptococcal glomerulonephritis and acute rheumatic fever: An uncommon coincidence.

Ann Pediatr Cardiol 2016 Sep-Dec;9(3):268-9

Center of Pediatrics, Children's Hospital, Affiliate of Vilnius University Hospital Santariskiu Klinikos, Vilnius, Lithuania; Clinic of Pediatrics, Faculty of Medicine, Vilnius University, Vilnius, Lithuania E-mail:

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http://dx.doi.org/10.4103/0974-2069.189115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007941PMC
September 2016
17 Reads

Post-streptococcal glomerulonephritis associated with atypical hemolytic uremic syndrome: to treat or not to treat with eculizumab?

Clin Kidney J 2016 Feb 26;9(1):90-6. Epub 2015 Nov 26.

Division of Nephrology, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.

A 7-year-old male with poststreptococcal glomerulonephritis (PSGN) developed hemolytic uremic syndrome (HUS) and achieved remission. He was treated with eculizumab for 1 year. The eculizumab was discontinued and the patient remained in remission. Read More

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http://dx.doi.org/10.1093/ckj/sfv119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720198PMC
February 2016
66 Reads

IgA-dominant acute poststreptococcal glomerulonephritis with concomitant rheumatic fever successfully treated with steroids: a case report.

Croat Med J 2015 Dec;56(6):567-72

Rina R. Rus, Division of Nephrology, University Children's Hospital, Bohoričeva 20, 1000 Ljubljana, Slovenia,

There are only a few reports of the co-occurrence of acute poststreptococcal glomerulonephritis (APGN) and acute rheumatic fever. We report an unusual case of a 3-year-old boy with nephrotic syndrome and acute renal failure with the transitional need for peritoneal dialysis, biopsy-proven atypical IgA-dominant APGN, and concomitant acute rheumatic fever, successfully treated by steroids. Aggressive treatment with pulses of methylprednisolone proved to be successful and we recommend its use in this type of cases. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4707928PMC
http://dx.doi.org/10.3325/cmj.2015.56.567DOI Listing
December 2015
16 Reads

Poststreptococcal acute glomerulonephritis presenting as posterior reversible encephalopathy syndrome in an eleven-year-old boy.

Minerva Pediatr 2015 Dec;67(6):531-3

Department of Pediatrics, S. Chiara University Hospital, Pisa, Italy -

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December 2015
12 Reads